Academic literature on the topic 'Lentiviral vector'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Lentiviral vector.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Lentiviral vector"
Yew, Chee-Hong Takahiro, Narmatha Gurumoorthy, Fazlina Nordin, Gee Jun Tye, Wan Safwani Wan Kamarul Zaman, Jun Jie Tan, and Min Hwei Ng. "Integrase deficient lentiviral vector: prospects for safe clinical applications." PeerJ 10 (August 12, 2022): e13704. http://dx.doi.org/10.7717/peerj.13704.
Full textLi, Chen, Biao Qian, Zhao Ni, Qinzhang Wang, Zixiong Wang, Luping Ma, Zhili Liu, Qiang Li, and Xinmin Wang. "Construction of recombinant lentiviral vector containing human stem cell leukemia gene and its expression in interstitial cells of cajal." Open Life Sciences 15, no. 1 (March 25, 2020): 83–91. http://dx.doi.org/10.1515/biol-2020-0010.
Full textPerry, Christopher, and Andrea C. M. E. Rayat. "Lentiviral Vector Bioprocessing." Viruses 13, no. 2 (February 9, 2021): 268. http://dx.doi.org/10.3390/v13020268.
Full textWang, Nan, Narendiran Rajasekaran, Tieying Hou, and Elizabeth Mellins. "Comparison of protein expression by different lentiviral vectors (51.12)." Journal of Immunology 188, no. 1_Supplement (May 1, 2012): 51.12. http://dx.doi.org/10.4049/jimmunol.188.supp.51.12.
Full textNguyen, Tuan Huy, Tatiana Khakhoulina, Andrew Simmons, Philippe Morel, and Didier Trono. "A Simple and Highly Effective Method for the Stable Transduction of Uncultured Porcine Hepatocytes Using Lentiviral Vector." Cell Transplantation 14, no. 7 (August 2005): 489–96. http://dx.doi.org/10.3727/000000005783982828.
Full textKubo, Shuji, and Kohnosuke Mitani. "A New Hybrid System Capable of Efficient Lentiviral Vector Production and Stable Gene Transfer Mediated by a Single Helper-Dependent Adenoviral Vector." Journal of Virology 77, no. 5 (March 1, 2003): 2964–71. http://dx.doi.org/10.1128/jvi.77.5.2964-2971.2003.
Full textSakuma, Toshie, Michael A. Barry, and Yasuhiro Ikeda. "Lentiviral vectors: basic to translational." Biochemical Journal 443, no. 3 (April 16, 2012): 603–18. http://dx.doi.org/10.1042/bj20120146.
Full textBreckpot, Karine, David Escors, Frederick Arce, Lucienne Lopes, Katarzyna Karwacz, Sandra Van Lint, Marleen Keyaerts, and Mary Collins. "HIV-1 Lentiviral Vector Immunogenicity Is Mediated by Toll-Like Receptor 3 (TLR3) and TLR7." Journal of Virology 84, no. 11 (March 17, 2010): 5627–36. http://dx.doi.org/10.1128/jvi.00014-10.
Full textPark, Frank. "Lentiviral vectors: are they the future of animal transgenesis?" Physiological Genomics 31, no. 2 (October 2007): 159–73. http://dx.doi.org/10.1152/physiolgenomics.00069.2007.
Full textLucke, Susann, Thomas Grunwald, and Klaus Überla. "Reduced Mobilization of Rev-Responsive Element-Deficient Lentiviral Vectors." Journal of Virology 79, no. 14 (July 2005): 9359–62. http://dx.doi.org/10.1128/jvi.79.14.9359-9362.2005.
Full textDissertations / Theses on the topic "Lentiviral vector"
Trimby, Christopher Matthew. "STRATEGIES FOR TARGETING LENTIVIRAL VECTORS." UKnowledge, 2011. http://uknowledge.uky.edu/gradschool_diss/157.
Full textIngrao, Dina. "Etude de l'étape d'entrée des vecteurs lentiviraux dérivés du VIH-1 dans les cellules hématopoïétiques humaines." Thesis, Evry-Val d'Essonne, 2013. http://www.theses.fr/2013EVRY0021/document.
Full textLentiviral vectors (LV) are used for various gene transfer applications, notably for hematopoietic gene therapy, but methods are lacking to precisely evaluate parameters that control the efficiency of transduction in relation with the entry of vectors into target cells. We adapted a fluorescence resonance energy transfer (FRET)-based HIV-1 fusion assay to measure the entry of non-replicative recombinant LV in various cell types, including primary human hematopoietic stem and progenitor cells, and to quantify the level of transduction of he same initially-infected cells. The assay utilizes recombinant LV containing betalactamase (BLAM)-Vpr chimeric proteins (BLAM-LV) and encoding a truncated form of thelow affinity nerve growth factor receptor (DELTA-NGFR). This LV-based fusion/transduction assay is a dynamic and versatile tool, revealing for instance the extent of lentiviral post-entry restrictions occuring in cells of hematopoietic origin. The assay also shows that transduction enhancers like Vectofusin®-1 or Retronectin® can partially relieve this post-entry block but their effects differ in the way to promote LV entry. Furthermore, our results show that Vectofusin®-1 acts at the entry step by promoting the adhesion and the fusion between lentiviral and cellular membranes. In conclusion, one such assay should be useful to study hematopoietic post-entry restrictions directed against LV and should allow improvements in various LV-based gene therapy protocols
Thomas, Joan Helen. "Studies in gene transfer using pseudotyped lentiviral vector systems." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621818.
Full textGelinas, Jean-Francois. "Enhancement of lentiviral vector production through alteration of virus-cell interactions." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:9921b8b4-e2b5-4eec-9efc-6036765c8d55.
Full textZhang, Bing. "Lentiviral vector-mediated gene transfer in vitro and in vivo /." St. Lucia, Qld, 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18024.pdf.
Full textBooth, C. A. "Lentiviral vector mediated gene therapy for X-linked lymphoproliferative disease." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1356299/.
Full textMacdonald, D. "Lentiviral vector vaccines for T-cell-mediated protection against influenza." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1417882/.
Full textOakland, Mayumi. "Improving lentiviral vector-mediated gene transfer by understanding cellular barriers." Diss., University of Iowa, 2013. https://ir.uiowa.edu/etd/4709.
Full textMekkaoui, Leila. "Lentiviral vector purification using genetically encoded biotin mimic in packaging cell." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10053191/.
Full textFIRRITO, CLAUDIA. "Targeted Gene Correction and Reprogramming of SCID-X1 Fibroblasts to Rescue IL2RG Expression in iPSC-derived Hematopoietic Cells." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2015. http://hdl.handle.net/10281/94656.
Full textGene replacement by integrating vectors has been successfully used to treat several inherited diseases, such as Lysosomal Storage Disorders (LSD), Thalassemia and Primary Immunodeficiencies (PIDs). X-linked Combined Immunodeficiency (SCID-X1) is a fatal monogenic disorder, caused by mutation of the Interleukin 2 Receptor common γ-chain (IL2RG) gene. For SCID-X1, the early clinical studies have clearly shown the therapeutic potential of integrating vector based gene replacement therapy, which achieved efficient lymphoid reconstitution thanks to the selective growth advantage of the genetically modified cells. However, these studies also highlighted the potential risk of insertional mutagenesis due to random integration of the vector into the host cell genome and to unregulated transgene expression, thus calling for the development of safer gene therapy approaches. Here, by combining the Zinc Finger Nuclease (ZFNs) technology to induce site-specific DNA double-strand breaks (DSB) and of Integrase-Defective Lentiviral Vector (IDLV) to deliver a corrective donor template, we exploited Homology Driven Repair (HDR) to correct SCID-X1 mutation in situ, restoring both physiological expression and function of the IL2RG gene . By knocking-in a corrective IL2RG cDNA transgene downstream of its endogenous promoter in B-lymphoblastoid cells, which constitutively express IL2RG, and in primary T-lymphocytes, which requires IL2RG for their survival and growth, we provide evidence of physiologic activity of the gene-edited IL2RG gene. By including an excisable GFP- or a Puromycin Resistance (PuroR) expression cassette downstream of the corrective cDNA, we coupled correction with exogenous selection of corrected SCID-X1 primary fibroblasts, which do not physiologically express IL2RG, and obtained an enriched population of gene-corrected cells. We then reverted this population to pluripotency by using a novel reprogramming vector that expresses OCT4, SOX2, KLF4 and microRNA cluster 302-367 to obtain a potentially unlimited source of gene-corrected induced pluripotent stem cells (iPSC). We thus generated several gene-corrected bona-fide iPSCs, as confirmed by molecular analyses for targeted integration, which were characterized for their pluripotent state. IDLV-mediated transient delivery of the Cre-recombinase resulted in the co-excision of the reprogramming vector together with the selector cassette, thus allowing the generation of several gene-corrected, reprogramming-factor free iPSCs with normal karyotypes. Finally, by differentiating corrected iPSC to T-lymphoid progenitor cells, which are lacking in SCID-X1 patients, and showing a selective growth advantage of those derived from corrected iPSCs, we provide evidence of the functional correction of the IL2RG mutant allele. Overall these data demonstrate the feasibility of our targeted gene editing strategy, which couples gene correction with cell reprogramming to generate disease-free IPSC, thus paving the way for the development of novel and safer therapeutic approaches for SCID-X1.
Books on the topic "Lentiviral vector"
Lentiviral vector systems for gene transfer. Georgetown, TX: Eurekah.com, 2003.
Find full textTrono, Didier, ed. Lentiviral Vectors. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56114-6.
Full textEscors, David, Karine Breckpot, Frederick Arce, Grazyna Kochan, and Holly Stephenson. Lentiviral Vectors and Gene Therapy. Basel: Springer Basel, 2012. http://dx.doi.org/10.1007/978-3-0348-0402-8.
Full textEscors, David. Lentiviral Vectors and Gene Therapy. Basel: Springer Basel, 2012.
Find full textMaurizio, Federico, ed. Lentivirus gene engineering protocols. Totowa, N.J: Humana Press, 2003.
Find full textFederico, Maurizio, ed. Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3753-0.
Full textMaurizio, Federico, ed. Lentivirus gene engineering protocols. 2nd ed. New York: Humana Press, 2010.
Find full textLentiviral Vector Systems for Gene Transfer (Medical Intelligence Unit, 31). Springer, 2003.
Find full textLentiviral Vector Systems for Gene Transfer (Medical Intelligence Unit, 31). Eurekah.com, 2001.
Find full textBuchschacher, Gary L. Lentiviral Vector Systems for Gene Transfer (Medical Intelligence Unit, 31). Eurekah.com, 2001.
Find full textBook chapters on the topic "Lentiviral vector"
Larochelle, A., K. W. Peng, and S. J. Russell. "Lentiviral Vector Targeting." In Current Topics in Microbiology and Immunology, 143–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56114-6_7.
Full textSegura, María Mercedes, Alain Garnier, Yves Durocher, Sven Ansorge, and Amine Kamen. "New Protocol for Lentiviral Vector Mass Production." In Lentivirus Gene Engineering Protocols, 39–52. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-533-0_2.
Full textRamezani, Ali, and Robert G. Hawley. "Strategies to Insulate Lentiviral Vector-Expressed Transgenes." In Lentivirus Gene Engineering Protocols, 77–100. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-533-0_5.
Full textHan, Shuhong, and Lung-Ji Chang. "Immunity of Lentiviral Vector-Modified Dendritic Cells." In Gene Therapy of Cancer, 245–59. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-561-9_13.
Full textChong, Mark S. K., and Jerry Chan. "Lentiviral Vector Transduction of Fetal Mesenchymal Stem Cells." In Lentivirus Gene Engineering Protocols, 135–47. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-533-0_9.
Full textCui, Yan, and Lung-Ji Chang. "Detection and Selection of Lentiviral Vector-Transduced Cells." In Lentivirus Gene Engineering Protocols, 69–85. Totowa, NJ: Humana Press, 2003. http://dx.doi.org/10.1385/1-59259-393-3:69.
Full textScherr, Michaela, Letizia Venturini, and Matthias Eder. "Lentiviral Vector-Mediated Expression of pre-miRNAs and AntagomiRs." In Lentivirus Gene Engineering Protocols, 175–85. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-533-0_12.
Full textter Brake, Olivier, Jan-Tinus Westerink, and Ben Berkhout. "Lentiviral Vector Engineering for Anti-HIV RNAi Gene Therapy." In Lentivirus Gene Engineering Protocols, 201–13. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-533-0_14.
Full textDu, Zhong-Wei, and Su-Chun Zhang. "Lentiviral Vector-Mediated Transgenesis in Human Embryonic Stem Cells." In Lentivirus Gene Engineering Protocols, 127–34. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-533-0_8.
Full textVerhoeyen, Els, Caroline Costa, and Francois-Loic Cosset. "Lentiviral Vector Gene Transfer into Human T Cells." In Genetic Modification of Hematopoietic Stem Cells, 97–114. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-409-4_8.
Full textConference papers on the topic "Lentiviral vector"
Ranzani, Marco, Daniela Cesana, Cynthia C. Bartholomä, Francesca Sanvito, Michela Riba, Mauro Pala, Fabrizio Benedicenti, et al. "Abstract 3169: Lentiviral vector-based insertional mutagenesis identifies new clinically relevant liver cancer genes." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3169.
Full textAlbershardt, Tina C., David J. Campbell, Andrea J. Parsons, Jan H. ter Meulen, and Peter Berglund. "Abstract 2506: Preclinical characterization of LV305, a lentiviral vector targeting tumors expressing NY-ESO-1." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2506.
Full textDwivedi, Alka, Ling Su, Justin Mirazee, Mehdi Benzaoui, Christopher Chien, Nirali Shah, Xiaolin Wu, and Naomi Taylor. "327 Clonal expansion of CD22 CAR T-cells following lentiviral vector integration in the PWWP3A gene." In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.0327.
Full textQin, Shi, and Jie Wang. "The construction of RGD-TAT-KDR siRNA fusion gene lentiviral vector and the study of its antitumor activityin vitro." In International Conference on Medical Engineering and Bioinformatics. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/meb140171.
Full textBajaj, Anshika, Tsai-Yu Lin, Lisa Y. Ngo, Michele Murphy, Brenna Kelley-Clarke, Wayne R. Gombotz, Jan H. ter Meulen, and Peter Berglund. "Abstract 5919: Component-specific qPCR assays for characterization and identity testing of multigenome ZVex®, a dendritic cell-targeting lentiviral vector platform." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-5919.
Full textBajaj, Anshika, Lisa Y. Ngo, Peter Berglund, and Jan ter Meulen. "Abstract 5092: ZVex® lentiviral vector strongly activates pro-inflammatory, antigen processing, and anti-viral defense response pathways in monocyte-derived dendritic cells." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5092.
Full textRanzani, Marco, Daniela Cesana, Cynthia Bartholomae, Francesca Sanvito, Mauro Pala, Fabrizio Benedicenti, Lucia Sergi Sergi, et al. "Abstract 4982: Identification of new human liver cancer genes by a novel lentiviral vector-based insertional mutagenesis approach in three mouse models of hepatocarcinogenesis." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4982.
Full textRanzani, Marco, Daniela Cesana, Cynthia C. Bartholomae, Francesca Sanvito, Mauro Pala, Fabrizio Benedicenti, Pierangela Gallina, et al. "Abstract 104: New liver cancer genes identified by lentiviral vector-based insertional mutagenesis in mice are associated to differential survival in hepatocellular carcinoma patients." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-104.
Full textBryson, Paul D., Xiaolu Han, Norman Truong, and Pin Wang. "Abstract 2888: Dendritic cell-targeted lentiviral vector vaccines overcome tolerance to generate a protective T-cell immune response to breast cancer antigens ERBB2 and α-lactalbumin." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2888.
Full textNicolai, Chris, Jim Qin, Way Wu, Mollie McDonnell, Erica Shirazi, Greyson Hamilton, Max Chen, et al. "1230 VivoVec lentiviral vector particles surface-engineered with T cell activating and co-stimulatory ligands enhancein vivoCAR T cell generation and antitumor activity." In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.1230.
Full textReports on the topic "Lentiviral vector"
Yes, Jiing-Kuan. Anti-Angiogenic Gene Therapy of Prostate Cancer with Lentiviral Vectors. Fort Belvoir, VA: Defense Technical Information Center, July 2004. http://dx.doi.org/10.21236/ada428533.
Full textYee, Jiing-Kuan. Anti-Angiogenic Gene Therapy of Prostate Cancer With Lentiviral Vectors. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada410315.
Full textYee, Jiing-Kuan. Anti-Angiogenic Gene Therapy of Prostate Cancer with Lentiviral Vectors. Fort Belvoir, VA: Defense Technical Information Center, July 2003. http://dx.doi.org/10.21236/ada418264.
Full text