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Journal articles on the topic 'Lateral interaction'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 March 2023

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1

Huang, Cheng-Hsin, Tong Wai Wong, Chen-Hsu Yu, Jing-Yuan Chang, Shing-Jong Huang, Shou-Ling Huang, and Richard P. Cheng. "Swapping the Positions in a Cross-Strand Lateral Ion-Pairing Interaction between Ammonium- and Carboxylate-Containing Residues in a β-Hairpin." Molecules 26, no. 5 (March 3, 2021): 1346. http://dx.doi.org/10.3390/molecules26051346.

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Cross-strand lateral ion-pairing interactions are important for antiparallel β-sheet stability. Statistical studies suggested that swapping the position of cross-strand lateral residues should not significantly affect the interaction. Herein, we swapped the position of ammonium- and carboxylate-containing residues with different side-chain lengths in a cross-strand lateral ion-pairing interaction in a β-hairpin. The peptides were analyzed by 2D-NMR. The fraction folded population and folding free energy were derived from the chemical shift data. The ion-pairing interaction energy was derived using double mutant cycle analysis. The general trends for the fraction folded population and interaction energetics remained similar upon swapping the position of the interacting charged residues. The most stabilizing cross-strand interactions were between short residues, similar to the unswapped study. However, the fraction folded populations for most of the swapped peptides were higher compared to the corresponding unswapped peptides. Furthermore, subtle differences in the ion-pairing interaction energy upon swapping were observed, most likely due to the “unleveled” relative positioning of the interacting residues created by the inherent right-handed twist of the structure. These results should be useful for developing functional peptides that rely on lateral ion-pairing interactions across antiparallel β-strands.

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2

Delpiano, R., J. C. Herrera M., and J. E. Coeymans A. "Characteristics of lateral vehicle interaction." Transportmetrica A: Transport Science 11, no. 7 (July 20, 2015): 636–47. http://dx.doi.org/10.1080/23249935.2015.1059377.

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3

Kuo, Rachel, Mon Mohapatra, and Rigoberto Lara Guzmán. "Lateral violences." Interactions 28, no. 6 (November 2021): 46–49. http://dx.doi.org/10.1145/3488714.

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4

Chen, Jin, Yaofeng Liu, and Jinglong Bo. "Numerical Simulation of Lateral Jet Interaction." Journal of Applied Mathematics and Physics 05, no. 09 (2017): 1686–93. http://dx.doi.org/10.4236/jamp.2017.59141.

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5

El Naggar, M. H., and M. Novak. "Nonlinear lateral interaction in pile dynamics." Soil Dynamics and Earthquake Engineering 14, no. 2 (January 1995): 141–57. http://dx.doi.org/10.1016/0267-7261(94)00028-f.

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6

Arias, Diana Jimena, Anthony Hosein, and Dave Saint-Amour. "Assessing Lateral Interaction in the Synesthetic Visual Brain." Vision 3, no. 1 (February 8, 2019): 7. http://dx.doi.org/10.3390/vision3010007.

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In grapheme-color synesthesia, letters and numbers evoke abnormal colored perceptions. Although the underlying mechanisms are not known, it is largely thought that the synesthetic brain is characterized by atypical connectivity throughout various brain regions, including the visual areas. To study the putative impact of synesthesia on the visual brain, we assessed lateral interactions (i.e., local functional connectivity between neighboring neurons in the visual cortex) by recording steady-state visual evoked potentials (ssVEPs) over the occipital region in color-grapheme synesthetes (n = 6) and controls (n = 21) using the windmill/dartboard paradigm. Discrete Fourier Transform analysis was conducted to extract the fundamental frequency and the second harmonics of ssVEP responses from contrast-reversing stimuli presented at 4.27 Hz. Lateral interactions were assessed using two amplitude-based indices: Short-range and long-range lateral interactions. Results indicated that synesthetes had a statistically weaker signal coherence of the fundamental frequency component compared to the controls, but no group differences were observed on lateral interaction indices. However, a significant correlation was found between long-range lateral interactions and the type of synesthesia experience (projector versus associator). We conclude that the occipital activity related to lateral interactions in synesthetes does not substantially differ from that observed in controls. Further investigation is needed to understand the impact of synesthesia on visual processing, specifically in relation to subjective experiences of synesthete individuals.

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7

Bruton, David A. S., David J. White, Chi Yin Cheuk, Malcolm Bolton, and Malcolm Carr. "Pipe-Soil Interaction Behaviour during Lateral Buckling." SPE Projects, Facilities & Construction 1, no. 03 (September 1, 2006): 1–9. http://dx.doi.org/10.2118/106847-pa.

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8

Ansari, Yousef, George Kouretzis, and Scott William Sloan. "Physical modelling of lateral sand–pipe interaction." Géotechnique 71, no. 1 (January 2021): 60–75. http://dx.doi.org/10.1680/jgeot.18.p.119.

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9

Tan, S. A., S. Q. Luo, and K. Y. Yong. "Simplified models for soil-nail lateral interaction." Proceedings of the Institution of Civil Engineers - Ground Improvement 4, no. 4 (January 2000): 141–52. http://dx.doi.org/10.1680/grim.2000.4.4.141.

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10

Abedzadeh, Farzad, and Ronald Y. S. Pak. "Continuum Mechanics of Lateral Soil–Pile Interaction." Journal of Engineering Mechanics 130, no. 11 (November 2004): 1309–18. http://dx.doi.org/10.1061/(asce)0733-9399(2004)130:11(1309).

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11

Ochoa, Mauricio, and Michael W. O'Neill. "Lateral Pile Interaction Factors in Submerged Sand." Journal of Geotechnical Engineering 115, no. 3 (March 1989): 359–78. http://dx.doi.org/10.1061/(asce)0733-9410(1989)115:3(359).

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12

Anagnostopoulos, Christos, and Michael Georgiadis. "Interaction of Axial and Lateral Pile Responses." Journal of Geotechnical Engineering 119, no. 4 (April 1993): 793–98. http://dx.doi.org/10.1061/(asce)0733-9410(1993)119:4(793).

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13

Trojnar, Krzysztof. "SOIL – HYBRID PILE INTERACTION UNDER LATERAL LOAD." Journal of Civil Engineering, Environment and Architecture XXXII, no. 4/2015 (January 10, 2015): 435–46. http://dx.doi.org/10.7862/rb.2015.208.

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14

Nam, Chunghee, M. D. Mascaro, and C. A. Ross. "Lateral Interaction of transverse magnetic domain walls." Journal of Applied Physics 113, no. 17 (May 7, 2013): 17B903. http://dx.doi.org/10.1063/1.4794187.

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15

Tu, S. ‐H L., and R. O. Scattergood. "Interaction of lateral cracks and plastic zones." Journal of Applied Physics 68, no. 8 (October 15, 1990): 3983–89. http://dx.doi.org/10.1063/1.346260.

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16

Oliveira, José R. M. S., Márcio S. S. Almeida, Maria C. F. Almeida, and Ricardo G. Borges. "Physical Modeling of Lateral Clay-Pipe Interaction." Journal of Geotechnical and Geoenvironmental Engineering 136, no. 7 (July 2010): 950–56. http://dx.doi.org/10.1061/(asce)gt.1943-5606.0000311.

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17

DAI, H. "Affinity Based Lateral Interaction Artificial Immune System." IEICE Transactions on Information and Systems E89-D, no. 4 (April 1, 2006): 1515–24. http://dx.doi.org/10.1093/ietisy/e89-d.4.1515.

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18

Sweeny, Timothy D., Marcia Grabowecky, Yee Joon Kim, and Satoru Suzuki. "Internal curvature signal and noise in low- and high-level vision." Journal of Neurophysiology 105, no. 3 (March 2011): 1236–57. http://dx.doi.org/10.1152/jn.00061.2010.

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How does internal processing contribute to visual pattern perception? By modeling visual search performance, we estimated internal signal and noise relevant to perception of curvature, a basic feature important for encoding of three-dimensional surfaces and objects. We used isolated, sparse, crowded, and face contexts to determine how internal curvature signal and noise depended on image crowding, lateral feature interactions, and level of pattern processing. Observers reported the curvature of a briefly flashed segment, which was presented alone (without lateral interaction) or among multiple straight segments (with lateral interaction). Each segment was presented with no context (engaging low-to-intermediate-level curvature processing), embedded within a face context as the mouth (engaging high-level face processing), or embedded within an inverted-scrambled-face context as a control for crowding. Using a simple, biologically plausible model of curvature perception, we estimated internal curvature signal and noise as the mean and standard deviation, respectively, of the Gaussian-distributed population activity of local curvature-tuned channels that best simulated behavioral curvature responses. Internal noise was increased by crowding but not by face context (irrespective of lateral interactions), suggesting prevention of noise accumulation in high-level pattern processing. In contrast, internal curvature signal was unaffected by crowding but modulated by lateral interactions. Lateral interactions (with straight segments) increased curvature signal when no contextual elements were added, but equivalent interactions reduced curvature signal when each segment was presented within a face. These opposing effects of lateral interactions are consistent with the phenomena of local-feature contrast in low-level processing and global-feature averaging in high-level processing.

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19

Sirosh, Joseph, and Risto Miikkulainen. "Topographic Receptive Fields and Patterned Lateral Interaction in a Self-Organizing Model of the Primary Visual Cortex." Neural Computation 9, no. 3 (March 1, 1997): 577–94. http://dx.doi.org/10.1162/neco.1997.9.3.577.

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This article presents a self-organizing neural network model for the simultaneous and cooperative development of topographic receptive fields and lateral interactions in cortical maps. Both afferent and lateral connections adapt by the same Hebbian mechanism in a purely local and unsupervised learning process. Afferent input weights of each neuron self organize into hill-shaped profiles, receptive fields organize topographically across the network, and unique lateral interaction profiles develop for each neuron. The model demonstrates how patterned lateral connections develop based on correlated activity and explains why lateral connection patterns closely follow receptive field properties such as ocular dominance.

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20

Lindell, Annukka K. "Lateral thinkers are not so laterally minded: Hemispheric asymmetry, interaction, and creativity." Laterality: Asymmetries of Body, Brain and Cognition 16, no. 4 (December 6, 2010): 479–98. http://dx.doi.org/10.1080/1357650x.2010.497813.

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21

Chen, Zhou, Siyuan Chen, Xijun Ye, and Yunlai Zhou. "A Study on a Mechanism of Lateral Pedestrian-Footbridge Interaction." Applied Sciences 9, no. 23 (December 3, 2019): 5257. http://dx.doi.org/10.3390/app9235257.

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Based on the pedestrian lateral force hybrid Van der Pol/Rayleigh model, this study investigates the interaction dynamic model of a pedestrian-flexible footbridge lateral coupling system. A multi scale method is adopted to decouple the equation. The paper also studies the nonlinear dynamic response of the pedestrian-footbridge coupling system as well as the relationship between the lateral displacement of pedestrians and flexible footbridges, and the lateral interaction of the two variables. The results show that with the same frequency tuning parameters, when the mass ratio of pedestrians and footbridges is very small, the larger the mass ratio is, the larger the lateral response amplitude of pedestrians becomes. Conversely, when the mass ratio of pedestrians and footbridges is much larger, the larger the mass ratio is, the smaller the response amplitude becomes. When the natural frequency of a footbridge is larger, its Phase Angle becomes larger. As the lateral amplitude of pedestrians increases, the Phase Angle approaches zero. Moreover, regarding the variation of the Phase Angle between the interaction force and footbridge lateral vibration speed based on the lateral relative displacement of pedestrians, of which the variation range is (0, π ), as the pedestrians’ lateral amplitude increases, the Phase Angle approaches − π / 2 . The dynamic load coefficient varies linearly with the lateral amplitude of pedestrian vibrations.

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22

Klingelhofer, J., R. B. Troyanovsky, O. Y. Laur, and S. Troyanovsky. "Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions." Journal of Cell Science 113, no. 16 (August 15, 2000): 2829–36. http://dx.doi.org/10.1242/jcs.113.16.2829.

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Classic cadherins are transmembrane receptors involved in cell type-specific calcium-dependent intercellular adhesion. The specificity of adhesion is mediated by homophilic interactions between cadherins extending from opposing cell surfaces. In addition, classic cadherins can self-associate forming lateral dimers. Whereas it is widely excepted that lateral dimerization of cadherins is critical for adhesion, details of this process are not known. Yet, no evidence for physical association between different classic cadherins in cells expressing complex cadherin patterns has been reported. To study lateral and adhesive intercadherin interactions, we examined interactions between two classic cadherins, E- and P-cadherins, in epithelial A-431 cells co-producing both proteins. We showed that these cells exhibited heterocomplexes consisting of laterally assembled E- and P-cadherins. These complexes were formed by a mechanism involving Trp(156) of E-cadherin. Removal of calcium ions from the culture medium triggered a novel Trp(156)-independent type of lateral E-cadherin-P-cadherin association. Notably, an antiparallel (adhesive) mode of interaction between these cadherins was negligible. The specificity of adhesive interaction was localized to the amino-terminal (EC1) domain of both cadherins. Thus, EC1 domain of classic cadherins exposes two determinants responsible for nonspecific lateral and cadherin type-specific adhesive dimerization.

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23

Konuk, Ibrahim. "Coupled lateral and axial soil-pipe interaction and lateral buckling Part I: Formulation." International Journal of Solids and Structures 132-133 (February 2018): 114–26. http://dx.doi.org/10.1016/j.ijsolstr.2017.09.011.

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24

Konuk, Ibrahim. "Coupled lateral and axial soil-pipe interaction and lateral buckling Part II: Solutions." International Journal of Solids and Structures 132-133 (February 2018): 127–52. http://dx.doi.org/10.1016/j.ijsolstr.2017.09.012.

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25

Luo, Shi Jie. "Asymmetrical Lateral Jet Interaction on a Slender Body in Supersonic Flow." Applied Mechanics and Materials 565 (June 2014): 107–12. http://dx.doi.org/10.4028/www.scientific.net/amm.565.107.

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The lateral jet interaction on a slender body with rudders in supersonic flow had been investigated by numerical simulation, when the lateral jet is not in the longitudinal symmetry plane. It was called Asymmetrical lateral jet interaction in this paper. The flow features of jet interaction flowfield on the surface of the body or in the space far from the surface at different angles of attack and total pressure of jet was analyzed. As a result, the lateral jet interaction disturbed the pressure distributions of the slender body, and it was divided into near-field interaction near jet and far-field interaction aft-body on the basis of distance to jet. With the variety of the angle of attack and total pressure of jet, the pressure distributions at the aft-body change tempestuously, thereby the normal and lateral load will be from positive to negative, or reverse. The results also showed that the far-field interaction played a major role in the lateral jet interaction on a slender body in supersonic flow. The far-field interaction was caused by the changing of the outflow direction and intensity. Besides, the force/moment amplification factors presented highly nonlinear with the variety of angle of attack and total pressure of jet.

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26

Aslkhalili, Amin, Hodjat Shiri, and Sohrab Zendehboudi. "Probabilistic Assessment of Lateral Pipeline–Backfill–Trench Interaction." Journal of Pipeline Systems Engineering and Practice 12, no. 3 (August 2021): 04021034. http://dx.doi.org/10.1061/(asce)ps.1949-1204.0000564.

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27

Huckauf, Anke, Dieter Heller, and Tatjana A. Nazir. "Lateral masking: Limitations of the feature interaction account." Perception & Psychophysics 61, no. 1 (January 1999): 177–89. http://dx.doi.org/10.3758/bf03211958.

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28

Kemp, Alan R. "I Interaction of Plastic Local and Lateral Buckling." Journal of Structural Engineering 111, no. 10 (October 1985): 2181–96. http://dx.doi.org/10.1061/(asce)0733-9445(1985)111:10(2181).

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29

GOH, S. H., and T. D. O'ROURKE. "SOIL-PILE INTERACTION DURING LIQUEFACTION-INDUCED LATERAL SPREAD." Journal of Earthquake and Tsunami 02, no. 01 (March 2008): 53–85. http://dx.doi.org/10.1142/s1793431108000232.

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This paper describes a numerical model for the analysis of foundation piles subjected to large lateral ground deformation triggered by liquefaction. The model involves the use of p-y curves, but avoids the empiricism associated with the selection of degradation coefficients or reduction factors. To obtain a proper p-y characterization of the reaction between laterally deformed liquefied soil and an embedded pile, triaxial extension is recognized as the most appropriate analogue for the loading conditions. A suite of undrained triaxial extension tests was carried out using Nevada sand to establish the relevant strength and deformation parameters. Using the material parameters obtained from these tests, 2D FLAC analyses were performed to develop strain-softening p-y curves. Application of these p-y curves to the analyses of centrifuge experiments involving lateral spread effects on piles yields good agreement between the computed and measured responses. The strain-softening model provides excellent predictions of the measured peak and residual moments. Furthermore, the computed soil pressure diagrams agree well with the recommendations made by the Japan Road Association, which were calibrated using case histories from the 1995 Kobe earthquake. The same p-y curves were applied to the analysis of a field problem involving an actual pile foundation subjected to lateral spread effects during the 1964 Niigata earthquake.

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30

Fenz, Susanne F., Timo Bihr, Daniel Schmidt, Rudolf Merkel, Udo Seifert, Kheya Sengupta, and Ana-Sunčana Smith. "Membrane fluctuations mediate lateral interaction between cadherin bonds." Nature Physics 13, no. 9 (June 12, 2017): 906–13. http://dx.doi.org/10.1038/nphys4138.

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31

Chen, C. C., H. T. Chen, and T. Sato. "Interocular lateral interaction subserves dichoptic positive color aftereffects." Journal of Vision 14, no. 10 (August 22, 2014): 790. http://dx.doi.org/10.1167/14.10.790.

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32

Shinde, Santosh, and Utpal Bhadra. "MicroRNA Gene Interaction in Amyotrophic Lateral Sclerosis Dataset." Dataset Papers in Science 2014 (June 30, 2014): 1–24. http://dx.doi.org/10.1155/2014/780726.

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All microRNAs (miRNAs) in amyotrophic lateral sclerosis (ALS) study were collected from public databases such as miRBase, mir2Disease, and Human miRNA and Disease Database (HMDD). These miRNA datasets were used for target identification; these sets of miRNAs were expressed in brain specific parts of brain such as midbrain, cerebellum, frontal cortex, and hippocampus. Gene’s information and sequences were collected from NCBI and KEGG databases. All miRNAs were used for target prediction against 35 ALS associated genes. Three programs were used for target identification, namely, miRanda, TargetScan, and PicTar. The dataset contained information about miRNA targets sites identified by each program. Intersection studies of three programs such as miRanda versus TargetScan, miRanda versus PicTar, and TargetScan versus PicTar were carried out with all datasets. Target sites identified by each program were further explored for distribution of target sites across 35 genes in 5′ UTR, CDS, and 3′ UTR for miRNAs expressed in midbrain, cerebellum, frontal cortex, and hippocampus as predicted. Dataset was also used for calculation of multiplicity and coopretivity; this information was then used for construction of complex gene-microRNA interaction map.

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33

Katsanos, N. A., F. Roubani-Kalantzopoulou, E. Iliopoulou, I. Bassiotis, V. Siokos, M. N. Vrahatis, and V. P. Plagianakos. "Lateral molecular interaction on heterogeneous surfaces experimentally measured." Colloids and Surfaces A: Physicochemical and Engineering Aspects 201, no. 1-3 (March 2002): 173–80. http://dx.doi.org/10.1016/s0927-7757(01)01036-6.

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34

Pan, Xiaochuan, and Masamichi Sakagami. "Causal interaction between lateral prefrontal cortex and striatum." Neuroscience Research 68 (January 2010): e296-e297. http://dx.doi.org/10.1016/j.neures.2010.07.1317.

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35

Golubov, A. A., A. V. Ustinov, and S. Shokhor. "Interaction between fluxons in lateral Josephson junction stacks." Physica C: Superconductivity 258, no. 3-4 (February 1996): 379–83. http://dx.doi.org/10.1016/0921-4534(96)00017-2.

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36

Bouadi, M., K. Jetto, A. Benyoussef, and A. Kenz. "The effect of lateral interaction on traffic flow." Physica A: Statistical Mechanics and its Applications 460 (October 2016): 76–87. http://dx.doi.org/10.1016/j.physa.2016.04.039.

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37

He, P., H. Dietrich, and K. Jacobi. "Lateral interaction of CO chemisorbed on Ru(0001)." Surface Science 345, no. 3 (January 1996): 241–46. http://dx.doi.org/10.1016/0039-6028(95)00885-3.

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38

Hemmat, Mahya, Brian T. Castle, Jonathan N. Sachs, and David J. Odde. "Multiscale Computational Modeling of Tubulin-Tubulin Lateral Interaction." Biophysical Journal 117, no. 7 (October 2019): 1234–49. http://dx.doi.org/10.1016/j.bpj.2019.08.011.

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39

Tian, Shuling, and Zongzi Peng. "Mesh Adaptation for Simulating Lateral Jet Interaction Flow." Aerospace 9, no. 12 (December 1, 2022): 781. http://dx.doi.org/10.3390/aerospace9120781.

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Under the condition of supersonic incoming flow, a missile lateral jet flow field has complex flow structures, such as a strong shock wave, an unsteady vortex and flow separation. In order to improve ability to capture complex flow structures in numerical simulation of lateral jets, this paper proposes a combined-grid adaptive method. When combined with finite volume approximation of second-order and h-type adaptive technology, our method was verified by numerical experiments, which shows that wave structure and vortex structure in the jet flow field can be effectively captured at the same time. In comparison of uniformly refined mesh results, it was found that accuracy of computed results and resolution of characteristic flow structures were significantly improved after mesh adaptation. In comparison of the pressure coefficient, it was found that the error between the adaptive mesh and the uniformly refined mesh was smaller, and the maximum errors of the base grid, adaptive grid and uniformly refined grid were 92.1% and 12.3%.

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40

Kida, Yuichiro, and Masao Sakaguchi. "Interaction mapping of the Sec61 translocon identifies two Sec61α regions interacting with hydrophobic segments in translocating chains." Journal of Biological Chemistry 293, no. 44 (September 13, 2018): 17050–60. http://dx.doi.org/10.1074/jbc.ra118.003219.

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Many proteins in organelles of the secretory pathway, as well as secretory proteins, are translocated across and inserted into the endoplasmic reticulum membrane by the Sec61 translocon, a protein-conducting channel. The channel consists of 10 transmembrane (TM) segments of the Sec61α subunit and possesses an opening between TM2b and TM7, termed the lateral gate. Structural and biochemical analyses of complexes of Sec61 and its ortholog SecY have revealed that the lateral gate is the exit for signal sequences and TM segments of translocating polypeptides to the lipid bilayer and also involved in the recognition of such hydrophobic sequences. Moreover, even marginally hydrophobic (mH) segments insufficient for membrane integration can be transiently stalled in surrounding Sec61α regions and cross-linked to them, but how the Sec61 translocon accommodates these mH segments remains unclear. Here, we used Cys-scanned variants of human Sec61α expressed in cultured 293-H cells to examine which channel regions associate with mH segments. A TM segment in a ribosome-associated polypeptide was mainly cross-linked to positions at the lateral gate, whereas an mH segment in a nascent chain was cross-linked to the Sec61α pore-interior positions at TM5 and TM10, as well as the lateral gate. Of note, cross-linking at position 180 in TM5 of Sec61α was reduced by an I179A substitution. We therefore conclude that at least two Sec61α regions, the lateral gate and the pore-interior site around TM5, interact with mH segments and are involved in accommodating them.

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41

Dilliott, Allison A., Catherine M. Andary, Meaghan Stoltz, Andrey A. Petropavlovskiy, Sali M. K. Farhan, and Martin L. Duennwald. "DnaJC7 in Amyotrophic Lateral Sclerosis." International Journal of Molecular Sciences 23, no. 8 (April 7, 2022): 4076. http://dx.doi.org/10.3390/ijms23084076.

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Protein misfolding is a common basis of many neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Misfolded proteins, such as TDP-43, FUS, Matrin3, and SOD1, mislocalize and form the hallmark cytoplasmic and nuclear inclusions in neurons of ALS patients. Cellular protein quality control prevents protein misfolding under normal conditions and, particularly, when cells experience protein folding stress due to the fact of increased levels of reactive oxygen species, genetic mutations, or aging. Molecular chaperones can prevent protein misfolding, refold misfolded proteins, or triage misfolded proteins for degradation by the ubiquitin–proteasome system or autophagy. DnaJC7 is an evolutionarily conserved molecular chaperone that contains both a J-domain for the interaction with Hsp70s and tetratricopeptide domains for interaction with Hsp90, thus joining these two major chaperones’ machines. Genetic analyses reveal that pathogenic variants in the gene encoding DnaJC7 cause familial and sporadic ALS. Yet, the underlying ALS-associated molecular pathophysiology and many basic features of DnaJC7 function remain largely unexplored. Here, we review aspects of DnaJC7 expression, interaction, and function to propose a loss-of-function mechanism by which pathogenic variants in DNAJC7 contribute to defects in DnaJC7-mediated chaperoning that might ultimately contribute to neurodegeneration in ALS.

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42

Gophna, Uri, and Yanay Ofran. "Lateral acquisition of genes is affected by the friendliness of their products." Proceedings of the National Academy of Sciences 108, no. 1 (December 13, 2010): 343–48. http://dx.doi.org/10.1073/pnas.1009775108.

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A major factor in the evolution of microbial genomes is the lateral acquisition of genes that evolved under the functional constraints of other species. Integration of foreign genes into a genome that has different components and circuits poses an evolutionary challenge. Moreover, genes belonging to complex modules in the pretransfer species are unlikely to maintain their functionality when transferred alone to new species. Thus, it is widely accepted that lateral gene transfer favors proteins with only a few protein–protein interactions. The propensity of proteins to participate in protein–protein interactions can be assessed using computational methods that identify putative interaction sites on the protein. Here we report that laterally acquired proteins contain significantly more putative interaction sites than native proteins. Thus, genes encoding proteins with multiple protein–protein interactions may in fact be more prone to transfer than genes with fewer interactions. We suggest that these proteins have a greater chance of forming new interactions in new species, thus integrating into existing modules. These results reveal basic principles for the incorporation of novel genes into existing systems.

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43

Luo, Shi-Jie, Yao-Feng Liu, and Yu-Wei Liu. "Visualization of asymmetric separation induced by lateral jet interaction on a slender body in supersonic flow." International Journal of Modern Physics B 34, no. 14n16 (April 20, 2020): 2040081. http://dx.doi.org/10.1142/s0217979220400810.

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The lateral jet interaction on a slender body in supersonic flow was investigated by numerical simulation. The spatial and surface flow characteristics induced by jet interaction were shown. As a result, when the lateral jet is not in the longitudinal symmetry plane, the jet interaction causes asymmetric separation flow of surface and space, and destroys the pressure distributions of the slender body. With different angle of attack and circumferential positions of jet, the flow characteristic of the after body for jet in asymmetry plane changes greatly. The results with and without jet interaction also show that the far-field interaction played a major role in the lateral jet interaction.

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He, Yun Xiang, and Heng Bin Wu. "Ground-Liner Interaction Analysis in Underground Opening." Advanced Materials Research 261-263 (May 2011): 1044–48. http://dx.doi.org/10.4028/www.scientific.net/amr.261-263.1044.

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The ground-liner interaction research has important engineering value for the underground engineering design optimization and evaluation of construction safety. The interface between ground and liner is considered. In this paper, the effect of different ground-liner stiffness ratio, lateral pressure coefficient, thickness and different interface stiffness ratio and other factors on the support structure for internal forces and interface stress is analyzed. The analysis results show that liner internal force and interface stress increase with the increase of stiffness ratio between liner and ground, and the impact is very significant. Effect of lateral pressure coefficient on liner internal force and interface stress mainly reflects on laws around the cavern, where 1 is the limitation of lateral pressure coefficient. It presents symmetrical distribution. With the increase of liner thickness, the liner internal force and interface normal stress increase, but it make no difference to the contact interface tangential stress.

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Kulik, Andrzej J., Małgorzata Lekka, Kyumin Lee, Grazyna Pyka-Fościak, and Wieslaw Nowak. "Probing fibronectin–antibody interactions using AFM force spectroscopy and lateral force microscopy." Beilstein Journal of Nanotechnology 6 (May 15, 2015): 1164–75. http://dx.doi.org/10.3762/bjnano.6.118.

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The first experiment showing the effects of specific interaction forces using lateral force microscopy (LFM) was demonstrated for lectin–carbohydrate interactions some years ago. Such measurements are possible under the assumption that specific forces strongly dominate over the non-specific ones. However, obtaining quantitative results requires the complex and tedious calibration of a torsional force. Here, a new and relatively simple method for the calibration of the torsional force is presented. The proposed calibration method is validated through the measurement of the interaction forces between human fibronectin and its monoclonal antibody. The results obtained using LFM and AFM-based classical force spectroscopies showed similar unbinding forces recorded at similar loading rates. Our studies verify that the proposed lateral force calibration method can be applied to study single molecule interactions.

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Zhen, Bin, Liang Chang, and Zigen Song. "An Inverted Pendulum Model Describing the Lateral Pedestrian-Footbridge Interaction." Advances in Civil Engineering 2018 (November 1, 2018): 1–12. http://dx.doi.org/10.1155/2018/5730162.

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In this paper, the lateral pedestrian-footbridge interaction is investigated by using the model of an inverted pendulum on a cart. The inverted pendulum and the cart separately represent the synchronous pedestrians and the footbridge. The pivot point of the inverted pendulum is considered to vibrate harmonically to model the walking motion of the pedestrians. The proposed inverted pendulum model avoids the difficulty of the determination of the lateral force induced by the pedestrians applying to the footbridge, which was usually treated based on a semiempirical approach in previous works. Moreover, the model can describe the whole process: how the lateral amplitude of the bridge increases from small to large. Measurement data showed that a normal pedestrian always keeps the ratio of 1/2 between the lateral and vertical step frequencies. The theoretical analysis for the inverted pendulum model indicates that such walking habit of pedestrians is the root of the frequency-locking phenomenon, which eventually results in excessive lateral vibrations of the bridge. Furthermore, such walking habit also is a key factor in the occurrence of the “jump phenomenon” in the London Millennium Bridge.

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Zhao, Xia, Zhao Li, Rui Fu, Chang Wang, and Yingshi Guo. "Differences in Drivers’ Glance Behavior and Lateral Control Ability during Full-Touch Interaction Mode and Conventional Interaction Mode: A Case Study of Road Experiments." Journal of Advanced Transportation 2022 (September 21, 2022): 1–13. http://dx.doi.org/10.1155/2022/5774250.

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In recent years, the full-touch human–machine interaction (HMI) mode has gained popularity in the automotive market. However, little research has been conducted on how this interaction mode affects drivers’ glance behavior and lateral control ability. In this study, we evaluated the visual engagement and driving performance of 30 participants while driving two vehicles equipped with either the full-touch interaction mode (FTIM) or the conventional interaction mode (CIM) provided by the original equipment manufacturer (OEM). We found that both air conditioning–related tasks required more visual engagement, longer task completion time, and worse lateral vehicle control under FTIM. Furthermore, the gray correlation analysis demonstrated that FTIM exhibited slightly different disadvantages in the two secondary tasks. In the temperature adjustment task, the correlations of glance behavior and lateral control ability between the two interactive modes were 0.688 and 0.680, respectively. In the airflow adjustment task, the correlations of glance behavior and lateral control ability between the two interactive modes were 0.659 and 0.668, respectively. In addition, this study revealed that driving speed had significant effects on glance behavior and lateral driving performance in both interaction modes. As speed increased, self-adjusting glance behavior was evident in performing the secondary task; however, this behavior could not compensate for the deterioration in lateral driving performance caused by the increased speed. The findings will help improve drivers’ perception of FTIM and provide theoretical guidance for the design development of HMI mode.

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Daiyan, Nasser, Shawn Kenny, Ryan Phillips, and Radu Popescu. "Investigating pipeline–soil interaction under axial–lateral relative movements in sand." Canadian Geotechnical Journal 48, no. 11 (November 2011): 1683–95. http://dx.doi.org/10.1139/t11-061.

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This paper presents results from an experimental and numerical study on the axial–lateral interaction of pipes with dense sand. A series of centrifuge tests were conducted, with a rigid pipeline displaced in the horizontal plane in a cohesionless test bed. The relative pipe–soil interaction included axial, lateral, and oblique loading events. A three-dimensional continuum finite element model was developed using ABAQUS/Standard ( Hibbitt et al. 2005 ) software. The numerical model was calibrated against experimental results. A parametric study was conducted, using the calibrated finite element model to extend the investigations. The ultimate axial and lateral soil loading was found to be dependent on the angle of attack for relative movement between the pipe and soil. Two different failure mechanisms were observed for axial–lateral pipeline–soil interaction. This study confirms and improves on a two-part failure criterion that accounts for axial–lateral coupling during oblique soil loading events on buried pipelines.

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Chang, Jing-Yuan, Yen-Jin Pan, Pei-Yu Huang, Yi-Ting Sun, Chen-Hsu Yu, Zhi-Jun Ning, Shou-Ling Huang, Shing-Jong Huang, and Richard P. Cheng. "The Effects of Charged Amino Acid Side-Chain Length on Diagonal Cross-Strand Interactions between Carboxylate- and Ammonium-Containing Residues in a β-Hairpin." Molecules 27, no. 13 (June 29, 2022): 4172. http://dx.doi.org/10.3390/molecules27134172.

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The β-sheet is one of the common protein secondary structures, and the aberrant aggregation of β-sheets is implicated in various neurodegenerative diseases. Cross-strand interactions are an important determinant of β-sheet stability. Accordingly, both diagonal and lateral cross-strand interactions have been studied. Surprisingly, diagonal cross-strand ion-pairing interactions have yet to be investigated. Herein, we present a systematic study on the effects of charged amino acid side-chain length on a diagonal ion-pairing interaction between carboxylate- and ammonium-containing residues in a β-hairpin. To this end, 2D-NMR was used to investigate the conformation of the peptides. The fraction folded population and the folding free energy were derived from the chemical shift data. The fraction folded population for these peptides with potential diagonal ion pairs was mostly lower compared to the corresponding peptide with a potential lateral ion pair. The diagonal ion-pairing interaction energy was derived using double mutant cycle analysis. The Asp2-Dab9 (Asp: one methylene; Dab: two methylenes) interaction was the most stabilizing (−0.79 ± 0.14 kcal/mol), most likely representing an optimal balance between the entropic penalty to enable the ion-pairing interaction and the number of side-chain conformations that can accommodate the interaction. These results should be useful for designing β-sheet containing molecular entities for various applications.

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Chen, Pei, Suxun Li, Shijie Luo, and Zhaoyong Ni. "Flow Visualization on Lateral Multiple Jet Interaction with Freestream." Journal of Flow Control, Measurement & Visualization 02, no. 01 (2014): 7–11. http://dx.doi.org/10.4236/jfcmv.2014.21002.

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