Academic literature on the topic 'Lateral interaction'

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Journal articles on the topic "Lateral interaction"

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Huang, Cheng-Hsin, Tong Wai Wong, Chen-Hsu Yu, Jing-Yuan Chang, Shing-Jong Huang, Shou-Ling Huang, and Richard P. Cheng. "Swapping the Positions in a Cross-Strand Lateral Ion-Pairing Interaction between Ammonium- and Carboxylate-Containing Residues in a β-Hairpin." Molecules 26, no. 5 (March 3, 2021): 1346. http://dx.doi.org/10.3390/molecules26051346.

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Cross-strand lateral ion-pairing interactions are important for antiparallel β-sheet stability. Statistical studies suggested that swapping the position of cross-strand lateral residues should not significantly affect the interaction. Herein, we swapped the position of ammonium- and carboxylate-containing residues with different side-chain lengths in a cross-strand lateral ion-pairing interaction in a β-hairpin. The peptides were analyzed by 2D-NMR. The fraction folded population and folding free energy were derived from the chemical shift data. The ion-pairing interaction energy was derived using double mutant cycle analysis. The general trends for the fraction folded population and interaction energetics remained similar upon swapping the position of the interacting charged residues. The most stabilizing cross-strand interactions were between short residues, similar to the unswapped study. However, the fraction folded populations for most of the swapped peptides were higher compared to the corresponding unswapped peptides. Furthermore, subtle differences in the ion-pairing interaction energy upon swapping were observed, most likely due to the “unleveled” relative positioning of the interacting residues created by the inherent right-handed twist of the structure. These results should be useful for developing functional peptides that rely on lateral ion-pairing interactions across antiparallel β-strands.
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Delpiano, R., J. C. Herrera M., and J. E. Coeymans A. "Characteristics of lateral vehicle interaction." Transportmetrica A: Transport Science 11, no. 7 (July 20, 2015): 636–47. http://dx.doi.org/10.1080/23249935.2015.1059377.

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Kuo, Rachel, Mon Mohapatra, and Rigoberto Lara Guzmán. "Lateral violences." Interactions 28, no. 6 (November 2021): 46–49. http://dx.doi.org/10.1145/3488714.

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Chen, Jin, Yaofeng Liu, and Jinglong Bo. "Numerical Simulation of Lateral Jet Interaction." Journal of Applied Mathematics and Physics 05, no. 09 (2017): 1686–93. http://dx.doi.org/10.4236/jamp.2017.59141.

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El Naggar, M. H., and M. Novak. "Nonlinear lateral interaction in pile dynamics." Soil Dynamics and Earthquake Engineering 14, no. 2 (January 1995): 141–57. http://dx.doi.org/10.1016/0267-7261(94)00028-f.

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Arias, Diana Jimena, Anthony Hosein, and Dave Saint-Amour. "Assessing Lateral Interaction in the Synesthetic Visual Brain." Vision 3, no. 1 (February 8, 2019): 7. http://dx.doi.org/10.3390/vision3010007.

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In grapheme-color synesthesia, letters and numbers evoke abnormal colored perceptions. Although the underlying mechanisms are not known, it is largely thought that the synesthetic brain is characterized by atypical connectivity throughout various brain regions, including the visual areas. To study the putative impact of synesthesia on the visual brain, we assessed lateral interactions (i.e., local functional connectivity between neighboring neurons in the visual cortex) by recording steady-state visual evoked potentials (ssVEPs) over the occipital region in color-grapheme synesthetes (n = 6) and controls (n = 21) using the windmill/dartboard paradigm. Discrete Fourier Transform analysis was conducted to extract the fundamental frequency and the second harmonics of ssVEP responses from contrast-reversing stimuli presented at 4.27 Hz. Lateral interactions were assessed using two amplitude-based indices: Short-range and long-range lateral interactions. Results indicated that synesthetes had a statistically weaker signal coherence of the fundamental frequency component compared to the controls, but no group differences were observed on lateral interaction indices. However, a significant correlation was found between long-range lateral interactions and the type of synesthesia experience (projector versus associator). We conclude that the occipital activity related to lateral interactions in synesthetes does not substantially differ from that observed in controls. Further investigation is needed to understand the impact of synesthesia on visual processing, specifically in relation to subjective experiences of synesthete individuals.
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Bruton, David A. S., David J. White, Chi Yin Cheuk, Malcolm Bolton, and Malcolm Carr. "Pipe-Soil Interaction Behaviour during Lateral Buckling." SPE Projects, Facilities & Construction 1, no. 03 (September 1, 2006): 1–9. http://dx.doi.org/10.2118/106847-pa.

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Ansari, Yousef, George Kouretzis, and Scott William Sloan. "Physical modelling of lateral sand–pipe interaction." Géotechnique 71, no. 1 (January 2021): 60–75. http://dx.doi.org/10.1680/jgeot.18.p.119.

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Tan, S. A., S. Q. Luo, and K. Y. Yong. "Simplified models for soil-nail lateral interaction." Proceedings of the Institution of Civil Engineers - Ground Improvement 4, no. 4 (January 2000): 141–52. http://dx.doi.org/10.1680/grim.2000.4.4.141.

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Abedzadeh, Farzad, and Ronald Y. S. Pak. "Continuum Mechanics of Lateral Soil–Pile Interaction." Journal of Engineering Mechanics 130, no. 11 (November 2004): 1309–18. http://dx.doi.org/10.1061/(asce)0733-9399(2004)130:11(1309).

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Dissertations / Theses on the topic "Lateral interaction"

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Dash, Suresh R. "Lateral pile soil interaction in liquefiable soils." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.543468.

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Christie, Robert. "Lateral jet interaction with a supersonic crossflow." Thesis, Cranfield University, 2010. http://dspace.lib.cranfield.ac.uk/handle/1826/6815.

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A lateral jet in a supersonic crossflow creates a highly complex three-dimensional flow field which is not easily predicted. The aim of this research was to assess the use of a RANS based CFD method to simulate a lateral jet in supersonic crossflow interaction by comparing the performance of available RANS turbulence models. Four turbulence models were trialled in increasingly complex configurations; a flat plate, a body of revolution and a body of revolution at incidence. The results of this numerical campaign were compared to existing experimental and numerical data. Overall the Spalart-Allmaras turbulence model provided the best fit to experimental data. The performance of the lateral jet as a reaction control system was assed by calculating the force and moment amplification factors. The predicted flowfield surrounding the interaction was analysed in detail and was shown to predict the accepted shock and vortical structures. The lateral jet interaction flowfield over a body of revolution was shown to be qualitatively the same as that over a flat plate. An experimental facility was designed and manufactured allowing the study of the lateral jet interaction in Cranfield University’s 2 ½” x 2 ½” supersonic windtunnel. The interaction was studied with a freestream Mach number of 1.8, 2.4 & 3.1 and over a range of pressure ratios (50≤PR≤200). Levels of unsteadiness in the interaction were measured using high bandwidth pressure transducers. The level of unsteadiness was quantified by calculating the OASPL of the pressure signal. OASPL was found to increase with increasing levels of PR or MPR and to decrease with increases of Mach number. The levels of unsteadiness found were low with the highest levels found downstream of the jet.
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Gong, Cencen. "The interaction between railway vehicle dynamics and track lateral alignment." Thesis, University of Huddersfield, 2013. http://eprints.hud.ac.uk/id/eprint/19755/.

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This thesis examines the effect of vehicle dynamics on lateral deterioration of the track alignment. As rail traffic runs along a route, the forces imposed upon the track cause the ballast to settle, and hence the track geometry deteriorates. At a specified value of deterioration the track geometry needs to be restored by tamping or other methods. As the deterioration is mainly in the vertical direction, this aspect has been more widely studied and models have been developed to predict vertical track geometry deterioration. On the other hand, lateral track deterioration is not as well understood, and this thesis aims to fill the gap in this knowledge. However, the understanding of the lateral deterioration mechanisms becomes more important as speed and capacity increase. This thesis describes statistical studies of track lateral deterioration, as well as the development and validation of a vehicle-track lateral dynamic interaction model. This work is undertaken to contribute to the fundamental understanding of the mechanisms of track lateral deterioration, therefore making the effective control and reduction of the lateral deterioration achievable. The statistical analysis provides a better understanding of three aspects of track lateral irregularities, namely: the relationship between vertical and lateral irregularities, the relationship between track curvature and track lateral irregularity and the change in track lateral deterioration over time. The vertical and lateral track irregularity magnitudes are clearly correlated. The track quality in the vertical direction is generally worse than in the lateral direction, however the number of track sections with lateral quality significantly worse than the vertical is non-negligible. The lateral irregularities tend to be larger on curves. It is notable that less than ten percent of the track studied has a constant lateral deterioration due to frequent maintenance activities and bidirectional lateral dynamic forces. Unlike vertical settlement, lateral deterioration develops exponentially in both magnitude and wavelength, and the major influences are found from the irregularities with wavelength longer than 10 m. The change in track lateral irregularity with different curve radii and the lateral deterioration rate are described in separate exponential power functions due to the limitation of the available track data. The parameters for these empirical equations do not remain constant due to the change in track conditions. Current track lateral models mainly focus on lateral failures such as buckling and lateral sliding. The development of lateral track irregularities tends to be studied using representative values of net lateral forces and net L/V (Lateral/Vertical) load ratios. Unlike other track lateral deterioration models, the model developed in this thesis focuses on the development of lateral irregularities based on the dynamic interactions between the vehicles and the track system. This model makes it possible to carry out more integrations and analysis of the track lateral deterioration in a realistic dynamic simulation, using vehicle models, contact conditions, track initial irregularities, and traffic mix more close to the reality. The vehicle-track lateral dynamic interaction model was validated against track geometry data measured on the West Coast Mainline (WCML) in England. It has been found that the model gives a reasonably accurate prediction of the development of lateral track irregularities. However, it also tends to predict a short wavelength deterioration that is not seen in the actual track deterioration. Improvements to the model are suggested by either adding more factors or simplifying the model depending on specific target application. Enhancing the model by including more details, such as longitudinal forces, temperature effect, more layered track systems, uneven track bed conditions and more representative wheel-rail contact conditions etc., may help understand the reason of the additional short wavelength. A sensitivity analysis was performed in order to identify the critical factors that influence lateral track deterioration. The track damage caused by specific vehicles can be controlled by understanding different vehicle dynamics behaviour on a particular track section or route. Vehicles with simple suspension design and heavy axle loads tend to cause more lateral track damage. Within a certain speed range, there will be a critical speed that generates the largest lateral deterioration. Vehicles with different dynamic behaviours can generate a potential offset of the lateral deterioration, so it is possible to design the traffic mix to cancel out the peak deterioration. However, it may not be very practical to redesign the traffic mix due to different traffic requirements. Subsequently, actions can be taken to effectively reduce track lateral deterioration, such as optimise the suspension design, vehicle weight, the selection of an optimal operation speed, and enhance the traffic mix design. As the most important interface between vehicle and track, the wheel-rail contact condition has an extremely large influence on lateral deterioration. Wheel and rail profiles with different wear conditions can cause altered vehicle-track lateral dynamic interaction. It is found that increasingly worn wheel/rail profiles within an acceptable tolerance can effectively reduce the lateral deterioration. Lateral deterioration can also be reduced by increasing all the track stiffness values, damping values and the mass of rails and sleepers, or alternatively, by decreasing the sleeper spacing. The sleeper-ballast interface is found to play the most important role in lateral deterioration. The interfaces between the sleeper and ballast shoulder, crib and base determines the non-linear characteristic such as hysteresis and sliding features. Improving the strength of the sleeper-ballast interface can improve the elastic limits and hysteresis characteristics, hence reducing the lateral deterioration. The findings of the investigation indicate that the model provides in-depth knowledge of the mechanisms influencing lateral deterioration and provides effective solutions with consideration of vehicles, wheel-rail contact and the track system. Further work would include track data with sufficient information in order to develop a more comprehensive empirical model that describes the lateral deterioration, inclusion of more potentially influential factors such as: temperature, ground condition, traffic etc. The model can be improved by taking into account additional factors such as the influence of longitudinal forces from the wheels to the rails, different weather and temperatures, subgrade and ground conditions, etc. The reason for the high frequency noise in the deterioration prediction is not understood yet and it should be discussed in terms of more accurate vehicle simulation results and more comprehensive rail and wheel worn profiles measured on the target track and vehicles. Furthermore, the sleeper-ballast lateral characteristics are not well understood and the previous research in this area is quite limited. To improve on the present work it would be useful to carry out laboratory tests in order to capture more accurately track lateral stiffness and damping values as well as the comprehensive non-linear characteristic of track lateral residual resistance behaviour.
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Pezzi, Luciano Ponzi. "Equatorial Pacific dynamics : lateral mixing and tropical instability waves." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274585.

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Dietrich, Undine. "Structural and dynamic studies of MARCKS interaction with PIP(2) containing lipid membranes." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-77727.

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MARCKS-Protein ist in den Signalübertragungsweg der Zelle involviert. Durch einen Adsorptions-/Desorptionszyklus mit der Zellmembran reguliert es die Konzentration bestimmter Botenmoleküle. Im Rahmen dieser Arbeit wurde untersucht, inwieweit strukturelle Änderungen der Membran, verursacht durch die Membran-Protein-Wechselwirkung, mit einem Reaktions-Diffusions-System korrelieren. Die elektrostatische Wechselwirkung von MARCKS-Protein mit negativ geladenen Membranlipiden geschieht an der inneren Seite der Zellmembran. Als Modellsystem lässt sich dies mit einer monomolekularen Lipidschicht an der Wasser-Luft-Grenzfläche realisieren. Anhand von oberflächensensitiven Messungen konnte gezeigt werden, dass die Wechselwirkung von MARCKS mit negativ geladenen Membranlipiden und damit die Adsorption an der Membran, zu einer Änderung der Membrantopologie führt. Damit verbundenen ist auch der partielle Einbau von MARCKS in die Membran, was zu einem größeren molekularen Flächenbedarf führt. Dieser korreliert mit dem Anstieg des lateralen Drucks der Lipidmonoschicht bei konstanter Fläche. Die Desorption von MARCKS kann durch die Wechselwirkung mit PKC induziert werden, detektierbar durch die Reduktion des lateralen Drucks. Bei Vorhandensein eines Reservoirs an MARCKS und PKC oszilliert der laterale Druck, was als zyklische Adsorption und Desorption von MARCKS an bzw. von der Lipidschicht interpretiert wird. Anhand der experimentellen Ergebnisse wurde ein mathematisches Modell entwickelt, dass dieses oszillierende Verhalten als ein Reaktions-Diffusions-System erklärt.
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Ahmed, Mahmoud Nasser Hussien. "Effects of Nonlinear Soil-Structure Interaction on Lateral Behavior of Pile Foundations." 京都大学 (Kyoto University), 2011. http://hdl.handle.net/2433/151949.

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Nemutudi, Rudzani. "Study of Pt-Ge interaction using thin film and lateral diffusion couples." Master's thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/17970.

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Bibliography: 104-107.
The formation of germanides of platinum has been investigated using both conventional thin films and lateral diffusion couples. The investigation was carried out using such established techniques as XRD, RBS and SEM. Using results from both thin film and lateral diffusion couples, a comparison has been made of the behaviour of Pt-Ge system in parameters such as phase formation sequence, growth kinetics and dominant diffusing species. In their sequential order of formation, three distinct phases, Pt₂Ge, PtGe and PtGe₂, have been identified in thin films in the temperature range 200 - 300°C. The first phase, Pt₂Ge, was found not to follow a layered mode of formation. Both PtGe and PtGe₂ phases were found to obey a (t)1/2 law, indicating a diffusion limited growth process. By employing Ti as an inert marker, platinum was observed as the dominant diffusing species during Pt₂Ge formation. On the dominant diffusing species during PtGe and PtGe₂ formation, the thin film results were but tentative. Upon annealing at 500°C/30,90,180min, lateral diffusion couples of Pt rich source (on Ge thin film) resulted in only a limited lateral growth, and multiple phases were not observed. However, when samples of Ge rich source (on Pt thin film) were annealed at the same temperature and times, lateral interaction was observed proceeding on a relatively large scale. Germanium atoms were found to have encroached into the surrounding Pt thin film as far as ±30μm away from the Ge source region, with multiple phases growing simultaneously, viz PtGe₂, PtGe and Pt₂Ge₃. Inside the source region, the composition of the innermost compound corresponded to PtGe₂ phase. Pt₂Ge₃ was located between PtGe₂ and the initial island/thin film interface line. The compound outside the source region was characterised as PtGe. Pt₂Ge₃ phase was observed to have resulted from PtGe₂ disintegration through the mechanism 2PtGe₂ -+ Pt₂Ge₃ + Ge. Plots obtained from μRBS and SEM lateral measurements indicate that the growth of observed phases (PtGe₂, Pt₂Ge₃ and PtGe) all follow a square-root-of-time law, a characteristic of diffusion limited growth process.
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Ahlberg, Eric Reid. "Interaction between soil and full scale drilled shafts under cyclic lateral loads." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1481677151&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Ramezanpanah, Zahra. "Bi-lateral interaction between a humanoid robot and a human in mixed reality." Electronic Thesis or Diss., université Paris-Saclay, 2020. http://www.theses.fr/2020UPASG039.

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Cette thèse peut être divisée en deux parties: la reconnaissance des actions et la reconnaissance des émotions. Chaque partie se fait selon deux méthodes, la méthode classique de Machine Learning et le réseau profond. Dans la section Reconnaissance des actions, nous avons d'abord défini un descripteur local basé sur la LMA, pour décrire les mouvements. LMA est un algorithme pour décrire un mouvement en utilisant ses quatre composants: le corps, l'espace, la forme et l'effort. Le seul objectif de cette partie étant la reconnaissance des gestes, seuls les trois premiers facteurs ont été utilisés. L'algorithme DTW, est implémenté pour trouver les similitudes des courbes obtenues à partir des vecteurs descripteurs obtenus par la méthode LMA. Enfin SVM, l'algorithme est utilisé pour former et classer les données. Dans la deuxième partie de cette section, nous avons construit un nouveau descripteur basé sur les coordonnées géométriques de différentes parties du corps pour présenter un mouvement. Pour ce faire, en plus des distances entre le centre de la hanche et les autres articulations du corps et les changements des angles de quaternion dans le temps, nous définissons les triangles formés par les différentes parties du corps et calculons leur surface. Nous calculons également l'aire de la seule frontière 3D conforme autour de toutes les articulations du corps. À la fin, nous ajoutons la vitesse de l'articulation différente dans le descripteur proposé. Nous avons utilisé LSTM pour évaluer ce descripteur. Dans la deuxième partie de cette thèse, nous avons d'abord présenté un module de niveau supérieur pour identifier les sentiments intérieurs des êtres humains en observant leurs mouvements corporels. Afin de définir un descripteur robuste, deux méthodes sont mises en œuvre: La première méthode est la LMA, qui en ajoutant le facteur «Effort» est devenue un descripteur robuste, qui décrit un mouvement et l'état dans lequel il a été effectué. De plus, le second sur est basé sur un ensemble de caractéristiques spatio-temporelles. Dans la suite de cette section, un pipeline de reconnaissance des mouvements expressifs est proposé afin de reconnaître les émotions des personnes à travers leurs gestes par l'utilisation de méthodes d'apprentissage automatique. Une étude comparative est faite entre ces 2 méthodes afin de choisir la meilleure. La deuxième partie de cette partie consiste en une étude statistique basée sur la perception humaine afin d'évaluer le système de reconnaissance ainsi que le descripteur de mouvement proposé
This thesis can be divided into two parts: action recognition and emotion recognition. Each part is done in two method, classic method of Machine Learning and deep network. In the Action Recognition section, we first defined a local descriptor based on the LMA, to describe the movements. LMA is an algorithm to describe a motion by using its four components: Body, Space, Shape and Effort. Since the only goal in this part is gesture recognition, only the first three factors have been used. The DTW, algorithm is implemented to find the similarities of the curves obtained from the descriptor vectors obtained by the LMA method. Finally SVM, algorithm is used to train and classify the data. In the second part of this section, we constructed a new descriptor based on the geometric coordinates of different parts of the body to present a movement. To do this, in addition to the distances between hip centre and other joints of the body and the changes of the quaternion angles in time, we define the triangles formed by the different parts of the body and calculated their area. We also calculate the area of the single conforming 3-D boundary around all the joints of the body. At the end we add the velocity of different joint in the proposed descriptor. We used LSTM to evaluate this descriptor. In second section of this thesis, we first presented a higher-level module to identify the inner feelings of human beings by observing their body movements. In order to define a robust descriptor, two methods are carried out: The first method is the LMA, which by adding the "Effort" factor has become a robust descriptor, which describes a movement and the state in which it was performed. In addition, the second on is based on a set of spatio-temporal features. In the continuation of this section, a pipeline of recognition of expressive motions is proposed in order to recognize the emotions of people through their gestures by the use of machine learning methods. A comparative study is made between these 2 methods in order to choose the best one. The second part of this part consists of a statistical study based on human perception in order to evaluate the recognition system as well as the proposed motion descriptor
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MIRRA, ALESSIA. "Functional interaction between FUS and SMN in the pathogenesis of amyotrophic lateral sclerosis." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2016. http://hdl.handle.net/2108/201799.

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Amyotrophic Lateral Sclerosis (ALS) is one of the most common motor neuron disease. ALS affects both upper and lower motor neurons, resulting in death within 3-5 years after symptoms onset. The recent identification of at least three RNA binding proteins as responsible for more than 60% of familiar cases of ALS highlighted the possibility that disturbed RNA metabolism could be a major pathogenic mechanism underlying the disease. Among all, FUS is an RNA binding protein, with a mainly nuclear localization, involved in several functions both in the nucleus, such as DNA transcription and RNA metabolism, and in the cytosol, as mRNA transport along the axons. Mutations of FUS, that account for about 5% of familial cases of ALS, mostly occur in the Nuclear Localization Domain (NLS) of the protein, thus inducing the formation of cytoplasmic aggregates, that are detectable in motor neurons of affected patients. FUS is part of the hnRNP family, a class of proteins able to directly bind intronic or exonic sequences to regulate splicing events. It is likely that FUS regulate alternative splicing also through the cooperation with SMN, a protein crucial for the maturation of the spliceosome. Indeed it has been demonstrated that FUS binds with components of the spliceosomalsnRNPs (small nuclear Ribonucleo Proteins, composed by small nuclear RNAs, snRNAU, and a set of different protein co-factors), such as SMN and proteins of the SMN-complex, thus contributing to the assembly and/or the maturation of the spliceosomal machinery. According to the role of FUS in the control of splicing, is not surprising that in FUS-related ALS impairment in the correct alternative splicing regulation occurs. Thisevidence suggests that alternative splicing defects could participate to the disease, linking ALS to another motor neuron disease where not only a deregulation of the splicing machinery occurs, but also, interestingly, SMN functions are directly involved: Spinal Muscular Atrophy (SMA). In SMA, similarly to what happens in ALS, the lower motor neurons are affected and patients, usually newborns, die for respiratory failure within few years after the diagnosis. SMA is caused by the depletion of Smn1gene, that encodes for SMN protein, the major constituent of the complex that mediates the maturation of spliceosomalsnRNPs. Indeed, in SMA patients and in animal models the correct assembly of snRNPs is affected, thus resulting in a general imbalance of the splicing regulation. Altogether these data suggest that FUS and SMN might cooperate to the same molecular pathway, i.e. alternative splicing regulation, and that disturbances in SMN-regulated functions, either caused by depletion of SMN protein (as in the case of SMA), or by pathogenic interactions between FUS and SMN (as in the case of ALS) might be a common theme in both ALS and SMA. This work was aimed at characterizing in vivo the role of SMN in the pathogenesis of FUS-related ALS. To this aim we used a mouse that overexpresses the human wild-type FUS (hFUS +/+) as ALS model, and we analyzed molecular phenotypes usually induced by SMN depletion. In particular, we observed the alteration of the splicing pattern of some target genes, whose splicing has been demonstrated affected in SMA models, that are particularly relevant for motor neuron viability. Furthermore we observed a decrease number of mature snRNPs from nuclei of motor neurons, that is a typical feature of tissues from SMA patients and models, thus suggesting a possible functional overlapping between FUS and SMN. However, molecular phenotypes induced by SMN lowering in SMA, such as the shortage of the RNAUs and their altered assembly in the core of the spliceosome, has not been observed in FUS mice. These data suggest that ALS and SMA converge in the alteration of the same pathway, but probably through different mechanisms. Yet, the shortage of SMN expression in this ALS model, obtained by crossing FUS mice (hFUS +/+) with SMN heterozygous knock-out mice (Smn +/-), did not modify the disease course nor the molecular phenotypes analyzed, thus reinforcing the existence of a complex interplay between FUS and SMN in the regulation of alternative splicing and gene expression.
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Books on the topic "Lateral interaction"

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Sundermeyer, Miles Aaron. Studies of lateral dispersion in the ocean. Woods Hole, Mass: Massachusetts Institute of Technology, Woods Hole Oceanographic Institution, Joint Program in Oceanography/Applied Ocean Science and Engineering, 1998.

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F, Van Impe W., ed. Single piles and pile groups under lateral loading. Rotterdam: Balkema, 2001.

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Johnson, D. E. Investigation of interactions between limb-manipulator dynamics and effective vehicle roll control characteristics. Edwards, Calif: Ames Research Center, 1986.

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Wang, Hsien-Yi Sabrina. Properties and interactions of the medial and the lateral perforant pathways in rat dentate gyrus. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1997.

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W, Boulanger Ross, Tokimatsu Kohji, University of California, Berkeley. Earthquake Engineering Research Center., American Society of Civil Engineers. Geo-Institute., and Tōkyō Kōgyō Daigaku. Toshi Jishin Kōgaku Sentā., eds. Seismic performance and simulation of pile foundations in liquefield and laterally spreading ground: Proceedings of a workshop, March 16-18, 2005, University of California, Davis, California. Reston, VA: American Society of Civil Engineers, 2005.

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Long Range Lateral Interaction in the On and Off Visual Pathways of Humans. Storming Media, 2004.

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Iskander, Magued, and Walid Aboumoussa. Rigidly Framed Earth Retaining Structures: Thermal Soil Structure Interaction of Buildings Supporting Unbalanced Lateral Earth Pressures. Springer, 2014.

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Iskander, Magued, and Walid Aboumoussa. Rigidly Framed Earth Retaining Structures: Thermal soil structure interaction of buildings supporting unbalanced lateral earth pressures. Springer, 2016.

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Iskander, Magued, and Walid Aboumoussa. Rigidly Framed Earth Retaining Structures: Thermal Soil Structure Interaction of Buildings Supporting Unbalanced Lateral Earth Pressures. Springer Berlin / Heidelberg, 2014.

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Reese, L. C., and William F. van Impe. Single piles and pile groups under lateral loading (HBK). Taylor & Francis, 2000.

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Book chapters on the topic "Lateral interaction"

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Danielsson, Lars, Henrik Lind, Evangelos Bekiaris, Maria Gemou, Angelos Amditis, Maurizio Miglietta, and Per Stålberg. "HMI Principles for Lateral Safe Applications." In Universal Access in Human-Computer Interaction. Ambient Interaction, 330–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-73281-5_35.

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Moody, John. "Dynamics of Lateral Interaction Networks." In International Neural Network Conference, 1001–4. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0643-3_165.

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Lazebnik, George E., and Gregory P. Tsinker. "Lateral Earth Pressure “At Rest”." In Monitoring of Soil-Structure Interaction, 165–83. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5979-5_10.

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Palmerius, Karljohan Lundin. "Adding Tangential Forces in Lateral Exploration of Stiffness Maps." In Haptic and Audio Interaction Design, 1–10. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-22950-3_1.

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Sirosh, Joseph, and Risto Miikkulainen. "Modeling Cortical Plasticity Based on Adapting Lateral Interaction." In The Neurobiology of Computation, 305–10. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2235-5_50.

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Fahmy, George S. "Reinforced Embankments on Soft Soil, Focus on Lateral Spreading." In Dynamic Soil-Structure Interaction for Sustainable Infrastructures, 53–61. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-01920-4_5.

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Chen, Shi-Ming, Yun-Feng Dong, and Xiao-Lei Wang. "Lateral Jet Interaction Model Identification Based on Genetic Programming." In Artificial Intelligence and Computational Intelligence, 484–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-23881-9_63.

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Fernández-Caballero, Antonio, Jose Mira, Ana E. Delgado, Miguel A. Fernández, and Maria T. López. "Lateral Interaction in Accumulative Computation: Motion-Based Grouping Method." In Brain, Vision, and Artificial Intelligence, 396–405. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/11565123_38.

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Dyer, K. R. "Estuarine Flow Interaction with Topography Lateral and Longitudinal Effects." In Estuarine Circulation, 39–59. Totowa, NJ: Humana Press, 1989. http://dx.doi.org/10.1007/978-1-4612-4562-9_2.

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Bonab, M. Hajialilue, J.-L. Chazelas, C. Favraud, and D. Levacher. "Simulation of soil-pile interaction under lateral impact loads." In Physical Modelling in Geotechnics, 415–19. London: Routledge, 2022. http://dx.doi.org/10.1201/9780203743362-76.

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Conference papers on the topic "Lateral interaction"

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Moody, J. "Dynamics of lateral interaction networks." In 1990 IJCNN International Joint Conference on Neural Networks. IEEE, 1990. http://dx.doi.org/10.1109/ijcnn.1990.137886.

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Zhou, Jing, Yuxiao Liu, and Xin Li. "Pipe Walking-Lateral Buckling Interaction." In 12th Biennial International Conference on Engineering, Construction, and Operations in Challenging Environments; and Fourth NASA/ARO/ASCE Workshop on Granular Materials in Lunar and Martian Exploration. Reston, VA: American Society of Civil Engineers, 2010. http://dx.doi.org/10.1061/41096(366)317.

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Bolt, G. "Fault tolerance of lateral interaction networks." In 1991 IEEE International Joint Conference on Neural Networks. IEEE, 1991. http://dx.doi.org/10.1109/ijcnn.1991.170654.

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Zhang, Xiao Xiao, Arthur Bradley, and Larry Thibos. "Interaction between longitudinal and lateral chromatic aberrations." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1988. http://dx.doi.org/10.1364/oam.1988.mr40.

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Human eyes exhibit both longitudinal and lateral chromatic aberration. Achromatizing lenses have been designed to correct longitudinal chromatic aberration. However, these lenses are not designed to correct for the lateral chromatic aberration of the eye. Based on optical models of human eyes and two different achromatizing lenses,1,2 we have evaluated the relative effects on retinal image quality of longitudinal and lateral chromatic aberrations separately and in combination. The eye’s 2 diopters of longitudinal chromatic aberration may seem large, but with a 5-mm pupil its effect in the retinal image quality for a white p4 phosphor is comparable with that for a monochromatic source with only 0.1-0.2 diopters of blur. Although correction of longitudinal chromatic aberration improves paraxial image quality, it can degrade off-axis image quality. This is because longitudinal chromatic aberration can protect the eye from the contrast degradation effect of lateral chromatic aberration. Also, special care is required when using achromatizing lenses to prevent the introduction of more lateral chromatic aberration in the retinal image than is normally present in the unaided eye.
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Candy, T. Rowan, Anthony M. Norcia, and Uri Polat. "Preferential Loss of Lateral Interaction in Amblyopia." In Vision Science and its Applications. Washington, D.C.: Optica Publishing Group, 1998. http://dx.doi.org/10.1364/vsia.1998.saa.1.

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Amblyopia is an abnormality of form perception that is classically defined in terms of a reduction in letter acuity. Losses of letter acuity and vernier acuity are well correlated in amblyopia, and both these acuities are more severely affected than grating acuity (Levi and Klein, 1982). Tests of vernier acuity are thus likely to be sensitive indicators of form vision losses in the treatment of amblyopia.
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Phillips, Ryan, Arash Nobahar, and Joe Zhou. "Combined Axial and Lateral Pipe-Soil Interaction Relationships." In 2004 International Pipeline Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/ipc2004-0144.

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A recent study recommended design guideline improvements to assess ground movement hazards for buried pipeline response. A review identified a wide variation of normalised axial resistance factors. This paper presents a three-dimensional finite element parametric study of pipe-soil interaction under combined axial and lateral loading. The normalised axial resistance is found to be very sensitive to the direction of pipe displacement and controlled by the interface friction near pure axial motion. An interaction diagram is developed and a design equation is proposed for combined axial and lateral loading.
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Yotsuji, J. "Interaction of lateral electromagnetic waves with metallic surfaces." In QUANTITATIVE NONDESTRUCTIVE EVALUATION. AIP, 2002. http://dx.doi.org/10.1063/1.1472837.

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Chee, Jayden, Alastair Walker, and David White. "Effect of Lateral Pipe-Soil Interaction on Controlled Lateral Buckling Using Pre-Deformed Pipeline." In ASME 2018 37th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/omae2018-77154.

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A novel approach to eliminate the onset of global buckling in pipelines is investigated in the paper. The method is based on pre-deforming a pipeline continuously with a specific wavelength and amplitude prior to installation on the seabed. The response of the pipeline to applied high temperature and pressure was studied in conjunction with variations in the lateral pipe-soil interaction (PSI) — both as uniform friction along the pipe and also with locally varying friction. Pipe and seabed parameters representing a typical wet-insulated infield flow line on soft clay are used. The pre-deformed pipeline has a higher buckle initiation temperature compared to a straight pipeline due to the reduced effective axial force build-up resulting from the low axial stiffness generated by the pre-deformed lobes along the pipeline. The results from this paper show that the strains in the pre-deformed pipeline are not significantly affected by the local variability of lateral PSI but rather by the global mean PSI. At a typical lateral soil resistance, i.e. a friction coefficient of 0.5, lateral buckling occurs at a very high temperature level that is not common in the subsea operation. At a very low friction, i.e. 0.1, lateral buckling occurs at a lower operating temperature but the strain is insignificant. The longitudinal strain of the pipeline is not highly sensitive to the lateral PSI, which is a quite different response to an initially straight pipeline. Therefore, this method could prove to be a valuable tool for the subsea industry as it enables the pipeline to be installed and operated safely at very high temperatures without the need for lateral buckling design and installation of expensive structures as buckle initiators. Even if the pre-deformed pipeline buckles at a very high temperature, during cycles of heat-up and cool-down the buckle shape ‘shakes down’ by geometric rearrangement to minimize the energy, and in doing so creates a series of ‘short pipelines’ in which the longitudinal strain is self-controlled. The system is therefore shown to be very robust in the conditions investigated and not affected by one of the biggest unknowns in seabed pipeline engineering, which is the local variability in lateral PSI.
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Brown, G., M. Brunner, X. Qi, and I. Stanley. "Lateral Buckling Reliability Calculation Methodology Accounting for Buckle Interaction." In Offshore Technology Conference. Offshore Technology Conference, 2006. http://dx.doi.org/10.4043/17795-ms.

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Low, Han Eng, Benjamin Anderson, and Fraser Branby. "Pipe-Soil Interaction at Engineered Lateral Buckle Touchdown Zones." In Offshore Technology Conference Asia. Offshore Technology Conference, 2018. http://dx.doi.org/10.4043/28511-ms.

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Reports on the topic "Lateral interaction"

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DeSpirito, James. Turbulence Model Effects on Cold-Gas Lateral Jet Interaction in a Supersonic Crossflow. Fort Belvoir, VA: Defense Technical Information Center, June 2014. http://dx.doi.org/10.21236/ada606669.

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DeSpirito, James. Lateral Reaction Jet Flow Interaction Effects on a Generic Fin-Stabilized Munition in Supersonic Crossflows. Fort Belvoir, VA: Defense Technical Information Center, November 2013. http://dx.doi.org/10.21236/ada592880.

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DeSpirito, James. Effects of Turbulence Model on Prediction of Hot-Gas Lateral Jet Interaction in a Supersonic Crossflow. Fort Belvoir, VA: Defense Technical Information Center, July 2015. http://dx.doi.org/10.21236/ada619525.

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Dahal, Sachindra, and Jeffery Roesler. Passive Sensing of Electromagnetic Signature of Roadway Material for Lateral Positioning of Vehicle. Illinois Center for Transportation, November 2021. http://dx.doi.org/10.36501/0197-9191/21-039.

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Autonomous vehicles (AV) and advanced driver-assistance systems (ADAS) offer multiple safety benefits for drivers and road agencies. However, maintaining the lateral position of an AV or a vehicle with ADAS within a lane is a challenge, especially in adverse weather conditions when lane markings are occluded. For significant penetration of AV without compromising safety, vehicle-to-infrastructure sensing capabilities are necessary, especially during severe weather conditions. This research proposes a method to create a continuous electromagnetic (EM) signature on the roadway, using materials compatible with existing paving materials and construction methods. Laboratory testing of the proposed concept was performed on notched concrete-slab specimens and concrete prisms containing EM materials. An induction-based eddy-current sensor and magnetometers were implemented to detect the EM signature. The detected signals were compared to evaluate the effects of sensor height above the concrete surface, type of EM materials, EM-material volume, material shape, and volume of EM concrete prisms. A layer of up to 2 in. (5.1 cm) of water, ice, snow, or sand was placed between the sensor and the concrete slab to represent adverse weather conditions. Results showed that factors such as sensor height, EM-material volume, EM dosage, types of the EM material, and shape of the EM material in the prism were significant attenuators of the EM signal and must be engineered properly. Presence of adverse surface conditions had a negligible effect, as compared to normal conditions, indicating robustness of the presented method. This study proposes a promising method to complement existing sensors’ limitations in AVs and ADAS for effective lane-keeping during normal and adverse weather conditions with the help of vehicle-to-pavement interaction.
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Wang, Yao, Jeehee Lim, Rodrigo Salgado, Monica Prezzi, and Jeremy Hunter. Pile Stability Analysis in Soft or Loose Soils: Guidance on Foundation Design Assumptions with Respect to Loose or Soft Soil Effects on Pile Lateral Capacity and Stability. Purdue University, 2022. http://dx.doi.org/10.5703/1288284317387.

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The design of laterally loaded piles is often done in practice using the p-y method with API p-y curves representing the behavior of soil at discretized points along the pile length. To account for pile-soil-pile interaction in pile groups, AASHTO (2020) proposes the use of p-multipliers to modify the p-y curves. In this research, we explored, in depth, the design of lateral loaded piles and pile groups using both the Finite Element (FE) method and the p-y method to determine under what conditions pile stability problems were likely to occur. The analyses considered a wide range of design scenarios, including pile diameters ranging from 0.36 m (14.17 inches) to 1.0 m (39.37 inches), pile lengths ranging from 10 m (32.81 ft) to 20 m (65.62 ft), uniform and multilayered soil profiles containing weak soil layers of loose sand or normally consolidated (NC) clay, lateral load eccentricity ranging from 0 m to 10 m (32.81 ft), combined axial and lateral loads, three different pile group configurations (1×5, 2×5, and 3×5), pile spacings ranging from 3 to 5 times the pile diameter, two different load directions (“strong” direction and “weak” direction), and two different pile cap types (free-standing and soil-supported pile caps). Based on the FEA results, we proposed new p-y curve equations for clay and sand. We also examined the behavior of the individual piles in the pile groups and found that the moment applied to the pile cap is partly transferred to the individual piles as moments, which is contrary to the assumption often made that moments are fully absorbed by axial loads on the group piles. This weakens the response of the piles to lateral loading because a smaller lateral pressure is required to produce a given deflection when moments are transferred to the head of the piles as moments. When the p-y method is used without consideration of the transferred moments, unconservative designs result. Based on the FEA results, we proposed both a new set of p-multipliers and a new method to use when moment distribution between piles is not known, using pile efficiency instead to calculate the total capacity of pile groups.
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Ori, Naomi, and Mark Estelle. Role of GOBLET and Auxin in Controlling Organ Development and Patterning. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7697122.bard.

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The size and shape of plant leaves are extremely diverse within and among species, and are also sensitive to growth conditions. Compound leaves, such as those of tomato, maintain morphogenetic activity during early stages of their development, enabling them to elaborate lateral appendages such as leaflets. The aim of the research project was to understand the interaction between the plant hormone auxin, the putative auxin response inhibitor ENTIRE (E, SlIAA9) and the NAM/CUC transcription factor GOBLET (GOB) in compound-leaf development in tomato (Solanum lycopersicum). The specific aims of the project were: 1. Investigation of the role of GOB in compound-leaf development. 2. Characterization of E function in auxin signaling. 3. Characterization of the role of auxin in compound-leaf development. 4. Investigation of the genetic and molecular interaction between E and GOB. 5. Investigate the role of these factors in fruit development. There were no major changes in these objectives. GOB was shown to mark and promote the boundaries between the leaf and initiating leaflets. Its accurate distribution was found to be required for proper leaflet initiation and separation. E was found to interact with the TIR1 and AFB6 proteins in an auxin-dependant manner, indicating that these are functional auxin receptors that mediate E degradation in the presence of auxin. This was further supported by the stabilization of E by a mutation in domain II of the protein, which is thought to mediate its auxin-dependant degradation. Over expression of this stabilized form in tomato leaves and characterization of the e mutant phenotype and the E expression domain indicated that E acts between initiating leaflets to inhibit auxin response and lamina growth. Generation and analysis of tomato plants expressing the auxin response reporter DR5::VENUS, and analysis of the effect of auxin microapplication or overexpression of an auxin biosynthesis gene, indicated that auxin marks the sites of leaflet initiation and promotes lamina growth. Investigation of the molecular and genetic interaction between auxin, GOB and E revealed a complex network of mutual regulation that is utilized to precisely pattern the leaf margin in a manner that enables the combination of tight control and flexibility. E, auxin and GOB were shown to affect fruit development and fruit set, and in an extension of the project are currently utilized to identify new players that affect these processes. The research project yielded enhanced understanding of the mechanisms of compound leaf patterning and provided tools that will enable the manipulation of leaf shape and fruit set.
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Reddy, P. H. A qualitative study of quality of care in rural Karnataka. Population Council, 1995. http://dx.doi.org/10.31899/rh1995.1018.

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The Third Five-Year Plan (1961–66) aimed at reducing the crude birth rate in India to 25 per 1,000 population by 1973, however this goal has not been achieved. Several other demographic goals were set later, to be achieved by specified years, but they were deferred or revised. One major reason for the failure to achieve these goals was thought to be the lack of adequate infrastructural facilities for the family welfare program, thus it was decided to improve the institution–population ratio. The primary objective of this study is to assess the quality of interaction between clients and providers, and the quality of family welfare services. More specifically, the study examines how family welfare program personnel interact with clients in a given setting, the quality of interaction, how frequently such interaction takes place, the provider's view of, and satisfaction with, the information and quality of family welfare services provided, and the client's view of, and satisfaction with, the information and quality of family welfare services received. The focus of the investigation is on the family welfare program—the maternal and child health and family planning programs.
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ADAS, RSK. Nitrate Surveillance Monitoring Program (Annual Report May 2021 - March 2022). Food Standards Agency, December 2022. http://dx.doi.org/10.46756/sci.fsa.uau489.

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Every Member State is required to monitor and report levels of nitrate in specified foodstuffs as part of the European Commission regulation and the UK also requires this information as part of the collection of data to support the review of retained EU law in the UK and inform the setting of policy around maximum nitrate levels. The requirement to carry out monitoring for nitrate in lettuce, spinach and rocket is being met by the UK Nitrate Surveillance Programme. Results are presented for the period between 1st April 2021 and 31st March 2022. A total of 202 samples were collected within the sampling period, comprising of 130 lettuce, 9 rocket, 26 spinach samples. A further 37 samples categorised at “Other Green Leafy Vegetables”, which comprised of samples including mustard, mizuna, celery, Pak Choi and cabbage. The lowest average nitrate concentration was recorded in summer-grown iceberg lettuce (935.2 mg/kg), and no iceberg samples exceeded the maximum nitrate concentration. The highest average nitrate concentration was seen in winter grown non-iceberg lettuce grown under protection within the lettuce group (3242.2 mg/kg), and in winter-grown rocket overall (4271.2 mg/kg). The number of samples exceeding the maximum threshold increased this year to 7 samples – 2 samples of open-air non-iceberg lettuce sampled in the summer, 1 sample of protected non-iceberg lettuce in the summer, and 3 samples of spinach. A further 4 samples were within 10% of the maximum threshold. Consistent with previous years of this project, a strong correlation was found between nitrate concentration and sampling date, with samples collected later in the season showing greater concentrations, indicating potential interactions between nitrate accumulation and climate – particularly light levels and available soil moisture and the accumulation of nitrate in the soil through subsequent fertiliser applications with successive planting. Furthermore, there was significant interaction between nitrate accumulation, product type and cultivation type, which could be further explored to better identify risk factors associated with nitrate accumulation in leafy vegetables grown in the UK.
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Felix, Meier, Wilfried Rickels, Christian Traeger, and Martin Quaas. Working paper published on NETs in strategically interacting regions based on simulation and analysis in an extended ACE model. OceanNets, 2022. http://dx.doi.org/10.3289/oceannets_d1.5.

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Net-zero climate policies foresee deployment of atmospheric carbon dioxide removal wit geological, terrestrial, or marine carbon storage. While terrestrial and geological storage would be governed under the framework of national property rights, marine storage implies that carbon is transferred from one global common, the atmosphere, to another global common, the ocean, in particular if storage exceeds beyond coastal applications. This paper investigates the option of carbon dioxide removal (CDR) and storage in different (marine) reservoir types in an analytic climate-economy model, and derives implications for optimal mitigation efforts and CDR deployment. We show that the introduction of CDR lowers net energy input and net emissions over the entire time path. Furthermore, CDR affects the Social Cost of Carbon (SCC) via changes in total economic output but leaves the analytic structure of the SCC unchanged. In the first years after CDR becomes available the SCC is lower and in later years it is higher compared to a standard climate-economy model. Carbon dioxide emissions are first higher and then lower relative to a world without CDR. The paper provides the basis for the analysis of decentralized and potentially non-cooperative CDR policies.
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Godenau, Dirk. Migration and the economy. Observatorio de la Inmigración de Tenerife. Departamento de Geografía e Historia. Universidad de La Laguna. Tenerife, 2020. http://dx.doi.org/10.25145/r.obitfact.2020.02.

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Economic reasons are among the basic explanatory factors of migration, whether international or internally within a country. In turn, migratory movements have effects on the economy in terms of economic growth in general, but also in the different markets (work, housing, consumer goods, etc.) and public services (education, health, social services, etc.). The purpose of this document is to offer an overview of these interactions between migration and the economy in the case of the Canary Islands. To do this, certain conceptual clarifications will be made initially involving the mutual determination of both processes, before later providing specifics with evidence on the Canarian case for the main issues considered: the economic reasons for migration, and its impact on economic growth, the labour market and the living conditions of the immigrant population. The final section alludes to the importance of the institutional framework that regulates these relations between migration and the economy, which are far from being interpretable as a mechanical relationship and isolated from the political sphere.
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