Academic literature on the topic 'Late functionalization'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Late functionalization.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Late functionalization"
Börgel, Jonas, and Tobias Ritter. "Late-Stage Functionalization." Chem 6, no. 8 (August 2020): 1877–87. http://dx.doi.org/10.1016/j.chempr.2020.07.007.
Full textMcConnell, Cameron R., and Shih-Yuan Liu. "Late-stage functionalization of BN-heterocycles." Chemical Society Reviews 48, no. 13 (2019): 3436–53. http://dx.doi.org/10.1039/c9cs00218a.
Full textBellina, Fabio. "Late-stage Functionalization of (hetero)arenes." Current Organic Chemistry 25, no. 18 (October 22, 2021): 2045. http://dx.doi.org/10.2174/138527282518211007142734.
Full textMiller, Scott J., and Tobias Ritter. "Introduction: Remote and Late Stage Functionalization." Chemical Reviews 123, no. 24 (December 27, 2023): 13867–68. http://dx.doi.org/10.1021/acs.chemrev.3c00800.
Full textKumar Hota, Sudhir, Dilsha Jinan, Satya Prakash Panda, Rittwika Pan, Basudev Sahoo, and Sandip Murarka. "Organophotoredox‐Catalyzed Late‐Stage Functionalization of Heterocycles." Asian Journal of Organic Chemistry 10, no. 8 (June 7, 2021): 1848–60. http://dx.doi.org/10.1002/ajoc.202100234.
Full textCernak, Tim, Kevin D. Dykstra, Sriram Tyagarajan, Petr Vachal, and Shane W. Krska. "The medicinal chemist's toolbox for late stage functionalization of drug-like molecules." Chemical Society Reviews 45, no. 3 (2016): 546–76. http://dx.doi.org/10.1039/c5cs00628g.
Full textSon, Jongwoo. "Sustainable manganese catalysis for late-stage C–H functionalization of bioactive structural motifs." Beilstein Journal of Organic Chemistry 17 (July 26, 2021): 1733–51. http://dx.doi.org/10.3762/bjoc.17.122.
Full textBarham, Joshua P., and Jaspreet Kaur. "Site-Selective C(sp3)–H Functionalizations Mediated by Hydrogen Atom Transfer Reactions via α-Amino/α-Amido Radicals." Synthesis 54, no. 06 (October 25, 2021): 1461–77. http://dx.doi.org/10.1055/a-1677-6619.
Full textGreaney, Michael F., and David M. Whalley. "Recent Advances in the Smiles Rearrangement: New Opportunities for Arylation." Synthesis 54, no. 08 (December 1, 2021): 1908–18. http://dx.doi.org/10.1055/a-1710-6289.
Full textLiu, Zilei, Jie Li, Suhua Li, Gencheng Li, K. Barry Sharpless, and Peng Wu. "SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization." Journal of the American Chemical Society 140, no. 8 (February 16, 2018): 2919–25. http://dx.doi.org/10.1021/jacs.7b12788.
Full textDissertations / Theses on the topic "Late functionalization"
Brown, Alec Nathaniel. "Late-Stage Functionalization of 1,2-Dihydro-1,2-Azaborines." Thesis, Boston College, 2015. http://hdl.handle.net/2345/bc-ir:104564.
Full textDescribed herein are two distinct research projects focused on the development of metal-catalyzed late-stage functionalization strategies for 1,2-dihydro-1,2-azaborines separated into three chapters. The first chapter discusses the development, synthesis, and recent contributions to the field of azaborine chemistry. The second chapter details the development of rhodium catalyzed B-H bond activation for the synthesis of a new class of BN-stilbenes as well as the discovery of a novel B-H to B-Cl transformation that is successful both with B-H azaborines as well as other B-H containing compounds. The third chapter pertains to the development of a B-H and B-Cl tolerant C(3) functionalization strategy through the use of Negishi cross-coupling. Using this methodology, previously unreported isomers of BN-naphthalene and BN-indenyl have been synthesized and characterized
Thesis (PhD) — Boston College, 2015
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Chemistry
Canelli, Tommaso. "Development of tandem C-H borylation/functionalization procedures for late stage functionalization of compounds." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/9273/.
Full textBentley, Sierra Kathleen. "Selective Direct Borylation and Late-Stage Functionalization of 1,2-Azaborines:." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:109014.
Full textDescribed herein is the development of a method to directly borylate the C5-position of monocyclic 1,2-azaborines without the use of a metal catalyst, kinetic resolution or directing group. This method tolerates different substitution on the boron as well as at the C3-position of the azaborine. A new BN-isostere of the drug molecule, felbinac, was synthesized to demonstrate the application of this method
Thesis (MS) — Boston College, 2020
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Chemistry
Kaplaneris, Nikolaos [Verfasser]. "Resource-Economical C–H Activation for Late-Stage Functionalization / Nikolaos Kaplaneris." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2021. http://d-nb.info/1237128854/34.
Full textArmand, Jeremy Richard. "Late Stage Functionalization of 1,2-Azaborines for Application in Biomedical Research:." Thesis, Boston College, 2019. http://hdl.handle.net/2345/bc-ir:108646.
Full textChapter 1. Use of boron as a pharmacophore is as growing but still underdeveloped strategy for expanding chemical space in biomedical research. In addition to more established methods of incorporating boron in drug development, an attractive and emerging method of introducing boron into biologically active compounds is through boron-nitrogen containing heterocycles. In particular, the Liu group has focused on exploring the interactions of monocyclic 1,2-azaborines in biological space. In order to install complicated chemical functionality needed for further studies, methods for late stage functionalization of 1,2-azaborines must be developed. Described herein is a method for functionalizing 1,2-azaborine at the C3- and C5-positions, with bromine and iodine handles, respectively. Chapter 2. Described is the application of the turbo Grignard reaction to 1,2-azaborines bearing a B–Cl bond. The reaction utilizes iPrMgCl·LiCl to form aryl carbon nucleophiles and is tolerant of sensitive functional groups such as nitriles and esters. Development of the reaction obviates the need to use toxic organotin reagents to install aryl groups at the B-position that bear sensitive, electrophilic functionalities
Thesis (MS) — Boston College, 2019
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Chemistry
Chan, Jessica Zee. "Stereoselective Functionalization of Carbonyl Compounds and N-Alkylamines Promoted by Cooperative Catalysts:." Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:108940.
Full textThis dissertation describes the development of cooperative catalyst systems for the functionalization of monocarbonyl compounds and stereoselective transformations of alpha-C–H bonds of N-alkylamines, inspired by the concepts of frustrated Lewis pairs (FLPs). Prior to this dissertation research, practical and broadly applicable C–C and C–heteroatom bond forming reactions involving the FLP complexes that provide synthetically desirable products with high enantioselectivity remained to be developed. Chapter 1 of this dissertation describes the recent advances in the transformations involving FLPs and B(C₆F₅)₃-catalyzed reactions. Inspired by the unique capability of FLP catalysts to activate otherwise unreactive molecules, and circumvent undesirable acid–base complexation, we have developed potent cooperative acid/base catalysts for C–C bond forming reactions of various monocarbonyl compounds and an appropriate electrophile, which will be discussed in Chapter 2. Another reactivity of FLPs to be explored has to do with the catalytic and enantioselective reactions of N-alkylamines, where two Lewis acid catalysts with potentially overlapping functions, work cooperatively to activate alpha-amino C–H bonds and promote the enantioselective C–C bond forming reaction between N-alkylamines and a nucleophilic species. In Chapter 3, B(C₆F₅)₃-catalyzed union of N-alkylamines and silicon enolates followed by the enantioselective B(C₆F₅)₃/Mg–PyBOX-catalyzed alpha-alkylation of N-alkylamines and alpha,beta-unsaturated compounds to form beta-amino carbonyl compounds will be described. In Chapter 4, B(C₆F₅)₃/Cu–PyBOX-catalyzed alpha-C–H alkynylation of N-alkylamines and the applications in late-stage functionalization and stereoselective synthesis will be discussed
Thesis (PhD) — Boston College, 2020
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Chemistry
Schischko, Alexandra. "Late-Stage Peptide Functionalization by Ruthenium-Catalyzed C H Arylations and Alkylations." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2018. http://hdl.handle.net/11858/00-1735-0000-002E-E4F4-0.
Full textZhang, Zhuan. "Late Stage Modifications of Phosphines using Transition-Metal-Catalyzed C–H Bond Functionalization." Thesis, Rennes, Ecole nationale supérieure de chimie, 2020. http://www.theses.fr/2020ENCR0067.
Full textThe main objective of this PhD thesis deals with the preparation of polyfunctional phosphines by late-stage diversification of commercially available ligands. We have developed rhodium(I)-catalyzed ortho’- C–H bond alkylation of biarylphosphines. This new methodology provides a straightforward access to a large library of multifunctionalized phosphines. Some of these modified ligands outperformed commercially available phosphines in the Pd-catalyzed carboxylation of aryl bromides with carbon dioxide in the presence of a photoredox catalyst. To improve the diversity of biarylphosphines, we have also perfected the P(III)-directed C−H bond alkenylation of (dialkyl)- and (diaryl)biarylphosphines using internal alkynes. Chloride-free [Rh(OAc)(COD)]2 acts as a better catalyst than [RhCl(COD)]2. Conditions were developed to control the mono- and difunctionalization. One of these novel bisalkenylated (dialkyl)biarylphosphines was employed for the preparation of a palladium(II) complex, and some of these functionalized ligands outperformed their corresponding unfunctionalized phosphines in Pd-catalyzed amidation of sterically hindered aryl chlorides. Finally, we have also explored a novel protocol C–H bond alkylation of phosphines via 5- or 7- membered ring cyclometallated phosphineruthenium intermediates. These functionalized phosphines have potential to improve crosscoupling reactions of sterically hindered aryl (pseudo)halides
Poudel, Dhruba P. "Late-Stage Modification of Polyurethane Dendrimers Using Click Chemistry." Miami University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=miami1627490978861964.
Full textHanson, Susan Kloek. "Synthesis and reactivity studies of late transition metal complexes relevant to C-H bond activation and functionalization /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8631.
Full textBooks on the topic "Late functionalization"
Koepnick, Lutz. Culture in the Shadow of Trauma? Edited by Helmut Walser Smith. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780199237395.013.0031.
Full textBook chapters on the topic "Late functionalization"
Fujiwara, Yuta, and Phil S. Baran. "Radical-Based Late Stage C–H Functionalization of Heteroaromatics in Drug Discovery." In New Horizons of Process Chemistry, 103–20. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3421-3_8.
Full textNoisier, Anaïs F. M., and Ranganath Gopalakrishnan. "Oxime/Hydrazone Conjugation at Histidine: Late-Stage Functionalization Approach of Unprotected Peptides." In Methods in Molecular Biology, 35–48. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1617-8_4.
Full textKlopsch, Isabel, Ekaterina Yu Yuzik-Klimova, and Sven Schneider. "Functionalization of N2 by Mid to Late Transition Metals via N–N Bond Cleavage." In Nitrogen Fixation, 71–112. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/3418_2016_12.
Full textFriis, Stig D., Erik Weis, and Magnus J. Johansson. "HTE as a Tool in C–H Activation Reaction Discovery and Late-Stage Functionalization of Pharmaceuticals." In The Power of High-Throughput Experimentation: Case Studies from Drug Discovery, Drug Development, and Catalyst Discovery (Volume 2), 161–79. Washington, DC: American Chemical Society, 2022. http://dx.doi.org/10.1021/bk-2022-1420.ch010.
Full textTayeb, Azmil. "Overview of state functionalization of national education in Indonesia and Malaysia from the late 1800s to the present." In Islamic Education in Indonesia and Malaysia, 43–83. New York : Routledge, 2018. | Series: Routledge contemporary Southeast Asia series: Routledge, 2018. http://dx.doi.org/10.4324/9781351116862-2.
Full textPrato, Maurizio, Michele Maggini, and Gianfranco Scorrano. "Organic Functionalization of Fullerenes: Toward Materials and Biological Applications." In The Chemical Physics of Fullerenes 10 (and 5) Years Later, 285–94. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-015-8682-5_19.
Full textRubin, Yves. "Recent Aspects of the Functionalization Chemistry of Buckminsterfullerene (C60): Preparation of New materials and compounds of Biological Interest." In The Chemical Physics of Fullerenes 10 (and 5) Years Later, 295–328. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-015-8682-5_20.
Full textSberegaeva, Anna V., David Watts, and Andrei N. Vedernikov. "Oxidative Functionalization of Late Transition Metal–Carbon Bonds." In Advances in Organometallic Chemistry, 221–97. Elsevier, 2017. http://dx.doi.org/10.1016/bs.adomc.2017.03.001.
Full textLiao, Mengjie, and Bo Yao. "Late-Stage Peptide Modification Via Aspartic Acid as Endogenous Directing Group." In Studies in Health Technology and Informatics. IOS Press, 2023. http://dx.doi.org/10.3233/shti230825.
Full textRozman, Martin, and Miha Lukšič. "Morphology and Functionalization of Metal Foils and Other Surfaces for Electrochemical Applications." In Handbook of Research on Tribology in Coatings and Surface Treatment, 359–89. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-7998-9683-8.ch015.
Full textConference papers on the topic "Late functionalization"
Ahmad, Asad, Nathan Gallant, Rasim Guldiken, and Onursal Onen. "Surface Functionalization of an Ovarian Cancer Diagnostic Biosensor." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64311.
Full textKulcitki, Veaceslav, Catalina Cazacu, Olga Morarescu, Elena Pruteanu, Vladilena Girbu, Nicon Ungur, and Philippe Renaud. "Late stage functionalization of unactivated C-H bonds in terpenes – a fruitful field for free radical chemistry." In New frontiers in natural product chemistry, scientific seminar with international participation. Institute of Chemistry, 2021. http://dx.doi.org/10.19261/nfnpc.2021.ab13.
Full textBirca, Natalia, and Veaceslav Kulcitki. "Late stage functionalization of cyclic terpenoids by atom transfer radical addition. A convenient route towards nitrogen heterocycles." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab12.
Full textfruit, corinne, thierry besson, Marine Harari, and Florence Couly. "Late-Stage Sequential C-H Functionalization of Thiazolo[5,4-f]quina-zolin-9(8H)-one: Synthesis of a Library of Potential Kinase Inhibitors." In The 20th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-b002.
Full textLasagni, Andrés, Teja Roch, Matthias Bieda, Dimitri Benke, and Eckhard Beyer. "High speed surface functionalization using direct laser interference patterning, towards 1 m2/min fabrication speed with sub-μm resolution." In SPIE LASE, edited by Udo Klotzbach, Kunihiko Washio, and Craig B. Arnold. SPIE, 2014. http://dx.doi.org/10.1117/12.2041215.
Full textBittigkoffer, Lucas, Henry Roth, Martin Baumann, and Nils-Agne Feth. "Surface Functionalization of Nitinol Utilizing Ultrashort Laser Pulses." In SMST 2024. ASM International, 2024. http://dx.doi.org/10.31399/asm.cp.smst2024p0129.
Full textKowalczyk, T. C., T. Z. Kosc, K. D. Singer, A. J. Beuhler, D. A. Wargowski, P. A. Cahill, C. H. Seager, and M. B. Meinhardt. "Guest-Host Crosslinked Polyimides for Integrated Optics." In Organic Thin Films for Photonic Applications. Washington, D.C.: Optica Publishing Group, 1995. http://dx.doi.org/10.1364/otfa.1995.md.11.
Full text