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1

Zhao, Li-Quan, Huang Zhu, and Liang-Mao Li. "Laser-Assisted Subepithelial Keratectomy versus Laser In Situ Keratomileusis in Myopia: A Systematic Review and Meta-Analysis." ISRN Ophthalmology 2014 (June 12, 2014): 1–8. http://dx.doi.org/10.1155/2014/672146.

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This systematic review was to compare the clinical outcomes between laser-assisted subepithelial keratectomy (LASEK) and laser in situ keratomileusis (LASIK) for myopia. Primary parameters included mean manifest refraction spherical equivalent (MRSE), MRSE within ±0.50 diopters, uncorrected visual acuity (UCVA) ≥20/20, and loss of ≥1 line of best-corrected visual acuity (BCVA). Secondary parameters included flap complications and corneal haze. Twelve clinical controlled trials were identified and used for comparing LASEK (780 eyes) to LASIK (915 eyes). There were no significant differences in visual and refractive outcomes between the two surgeries for low to moderate myopia. The incidence of loss of ≥1 line of BCVA was significantly higher in moderate to high myopia treated by LASEK than LASIK in the mid-term and long-term followup. The efficacy (MRSE and UCVA) of LASEK appeared to be a significant worsening trend in the long-term followup. Corneal haze was more severe in moderate to high myopia treated by LASEK than LASIK in the mid-term and long-term followup. The flap-related complications still occurred in LASIK, but the incidence was not significantly higher than that in LASEK. LASEK and LASIK were safe and effective for low to moderate myopia. The advantage of LASEK was the absence of flap-related complications, and such procedure complication may occur in LASIK and affect the visual results. The increased incidence of stromal haze and regression in LASEK significantly affected the visual and refractive results for high myopia.
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2

Zhou, Jihong, Wei Gu, Shaowei Li, Lijuan Wu, Yan Gao, and Xiuhua Guo. "Predictors affecting myopic regression in − 6.0D to − 10.0D myopia after laser-assisted subepithelial keratomileusis and laser in situ keratomileusis flap creation with femtosecond laser-assisted or mechanical microkeratome-assisted." International Ophthalmology 40, no. 1 (September 30, 2019): 213–25. http://dx.doi.org/10.1007/s10792-019-01179-5.

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Abstract Purpose To investigate the predictive factors of postoperative myopic regression among subjects who have undergone laser-assisted subepithelial keratomileusis (LASEK), laser-assisted in situ keratomileusis (LASIK) flap created with a mechanical microkeratome (MM), and LASIK flap created with a femtosecond laser (FS). All recruited patients had a manifest spherical equivalence (SE) from − 6.0D to − 10.0D myopia. Methods This retrospective, observational case series study analyzed outcomes of refraction at 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively. Predictors affecting myopic regression and other covariates were estimated with the Cox proportional hazards model for the three types of surgeries. Results The study enrolled 496 eyes in the LASEK group, 1054 eyes in the FS-LASIK group, and 910 eyes in the MM-LASIK group. At 12 months, from − 6.0D to − 10.0D myopia showed that the survival rates (no myopic regression) were 52.19%, 59.12%, and 58.79% in the MM-LASIK, FS-LASIK, and LASEK groups, respectively. Risk factors for myopic regression included thicker postoperative central corneal thickness (P ≦ 0.01), older age (P ≦ 0.01), aspherical ablation (P = 0.02), and larger transitional zone (TZ) (P = 0.03). Steeper corneal curvature (Kmax) (P = 0.01), thicker preoperative central corneal thickness (P < 0.01), smaller preoperative myopia (P < 0.01), longer duration of myopia (P = 0.02), with contact lens (P < 0.01), and larger optical zone (OZ) (P = 0.02) were protective factors. Among the three groups, the MM-LASIK had the highest risk of postoperative myopic regression (P < 0.01). Conclusions The MM-LASIK group experienced the highest myopic regression, followed by the FS-LASIK and LASEK groups. Older age, aspheric ablation used, thicker postoperative central corneal thickness, and enlarging TZ contribute to myopic regression; steeper preoperative corneal curvature (Kmax), longer duration of myopia, with contact lens, thicker preoperative central corneal thickness, lower manifest refraction SE, and enlarging OZ prevent postoperative myopic regression in myopia from − 6.0D to − 10.0D.
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3

Yang, Aping, Shanshan Tian, and Ping Guo. "Relativistic density functional investigation of the mono-lanthanum silicide clusters LaSin (n=1-6): geometries, electronic properties and IR spectra." Journal of Physics: Conference Series 2393, no. 1 (December 1, 2022): 012023. http://dx.doi.org/10.1088/1742-6596/2393/1/012023.

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Abstract The mono-lanthanum silicide clusters LaSin (n=1-6) have been studied adopting the relativistic density functional calculation with generalized gradient approximation. Considering different spin configurations, we calculated and discussed the equilibrium geometries, charge populations, the HOMO-LUMO gaps, as well as infrared (IR) absorption spectra of LaSin (n=1-6) clusters. It is found that: the lowest-lying LaSin (n=1-6) clusters basically maintain a similar framework to the low-lying Sin+1 clusters, and the La atoms prefer the surface sites. The relative stabilities are investigated based on the calculation of fragmentation energies and, showing that LaSi2, LaSi4, and LaSi5 clusters have enhanced stabilities. Charge populations analysis shows that the charges transfer from La atom to Sin framework and the La atom acts as an electron donor. HOMO-LUMO gaps indicate that LaSi2 and LaSi5 clusters have higher chemical stabilities. IR absorption spectrum and vibrational mode analysis show that the highest frequency absorption peaks all correspond to the breathing mode of the silicon framework, and the characteristic infrared absorption peaks caused by La atom vibration, except for LaSi dimer, all appeared in the low-frequency region.
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4

Wyler, Daniel, and Massimo Camellin. "Epi-LASIK Versus Epi-LASEK." Journal of Refractive Surgery 24, no. 1 (January 1, 2008): S57—S63. http://dx.doi.org/10.3928/1081597x-20080101-11.

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5

de Benito-Llopis, Laura, and Miguel A. Teus. "Epi-LASIK versus LASEK and PRK." Journal of Cataract & Refractive Surgery 38, no. 4 (April 2012): 732. http://dx.doi.org/10.1016/j.jcrs.2012.01.021.

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6

Schlote, T., and M. Kynigopoulos. "LASIK und Femto-LASIK." Augenheilkunde up2date 6, no. 03 (August 5, 2016): 211–21. http://dx.doi.org/10.1055/s-0042-105221.

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7

Schlote, T., and M. Kynigopoulos. "LASIK und Femto-LASIK." Klinische Monatsblätter für Augenheilkunde 233, no. 09 (August 5, 2016): e29-e39. http://dx.doi.org/10.1055/s-0033-1358236.

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Die LASIK/Femto-LASIK stellt heutzutage das am meisten eingesetzte, laserchirurgische Verfahren zur Korrektur von Fehlsichtigkeiten weltweit dar. Im richtigen Indikationsbereich führt es zu hervorragenden Ergebnissen und ist mit einem niedrigen Langzeitrisiko verbunden. Trotzdem kann das Verfahren nicht bei jedem eingesetzt werden und setzt eine sorgfältige Diagnostik und Patientenselektion voraus. Auf Aspekte der präoperativen Diagnostik und Vorbereitung von Patienten für refraktive Lasereingriffe sei u. a. auf den in dieser Zeitschrift ebenfalls publizierten Beitrag „Diagnostik in der refraktiven Chirurgie“ verwiesen 1.
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8

Ye, Min-jie, Cai-yuan Liu, Rong-feng Liao, Zheng-yu Gu, Bing-ying Zhao, and Yi Liao. "SMILE and Wavefront-Guided LASIK Out-Compete Other Refractive Surgeries in Ameliorating the Induction of High-Order Aberrations in Anterior Corneal Surface." Journal of Ophthalmology 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/8702162.

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Purpose. To compare the change of anterior corneal higher-order aberrations (HOAs) after laser in situ keratomileusis (LASIK), wavefront-guided LASIK with iris registration (WF-LASIK), femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), and small incision lenticule extraction (SMILE).Methods. In a prospective study, 82 eyes underwent LASIK, 119 eyes underwent WF-LASIK, 88 eyes underwent FS-LASIK, and 170 eyes underwent SMILE surgery. HOAs were measured with Pentacam device preoperatively and 6 months after surgery. The aberrations were described as Zernike polynomials, and analysis focused on total HOAs, spherical aberration (SA), horizontal coma, and vertical coma over 6 mm diameter central corneal zone.Results. Six months postoperatively, all procedures result in increase of anterior corneal total HOAs and SA. There were no significant differences in the induced HOAs between LASIK and FS-LASIK, while SMILE induced fewer total HOAs and SA compared with LASIK and FS-LASIK. Similarly, WF-LASIK also induced less total HOAs than LASIK and FS-LASIK, but only fewer SA than FS-LASIK (P<0.05). No significant difference could be detected in the induced total HOAs and SA between SMILE and WF-LASIK, whereas SMILE induced more horizontal coma and vertical coma compared with WF-LASIK (P<0.05).Conclusion. FS-LASIK and LASIK induced comparable anterior corneal HOAs. Compared to LASIK and FS-LASIK, both SMILE and WF-LASIK showed advantages in inducing less total HOAs. In addition, SMILE also possesses better ability to reduce the induction of SA in comparison with LASIK and FS-LASIK. However, SMILE induced more horizontal coma and vertical coma compared with WF-LASIK, indicating that the centration of SMILE procedure is probably less precise than WF-LASIK.
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9

Taneri, Suphi, and Saskia Oehler. "Reply: Epi-LASIK versus LASEK and PRK." Journal of Cataract & Refractive Surgery 38, no. 4 (April 2012): 732–33. http://dx.doi.org/10.1016/j.jcrs.2012.01.022.

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10

AlArfaj, Khalid, and Mohamed M. Hantera. "Comparison of LASEK, mechanical microkeratome LASIK and Femtosecond LASIK in low and moderate myopia." Saudi Journal of Ophthalmology 28, no. 3 (July 2014): 214–19. http://dx.doi.org/10.1016/j.sjopt.2013.10.002.

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11

Low, Jin Rong, Li Lim, Jane Chwee Wah Koh, Daniel Kai Peng Chua, and Mohamad Rosman. "Simultaneous Accelerated Corneal Crosslinking and Laser In situ Keratomileusis for the Treatment of High Myopia in Asian Eyes." Open Ophthalmology Journal 12, no. 1 (July 23, 2018): 143–53. http://dx.doi.org/10.2174/1874364101812010143.

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Background: LASIK Xtra is a recently described technique which combines LASIK and accelerated corneal cross-linking(CXL) in the same setting. Its long-term outcome in Asians with high myopia is not well described. Objectives: To compare the efficacy, predictability and safety of LASIK Xtra with LASIK in patients with high myopia. Method: This is a retrospective study comparing 50 consecutive eyes undergoing LASIK Xtra for the correction of high myopia and/or myopic astigmatism (-6.63 to -15.50 D manifest spherical equivalent) with a matched control group of 50 eyes undergoing LASIK alone for correction of high myopia (-6.00 to -12.25 D manifest spherical equivalent). Mean follow-up was 5.7 months (range, 1.5-13.3 months) for LASIK Xtra and 3.6 months (range, 1.7-4.2 months) for LASIK only. Outcome measures included Uncorrected Distance Visual Acuity (UDVA), Corrected Distance Visual Acuity (CDVA), refraction and intraoperative and postoperative complications. Results: At post-operative 3 months, all eyes achieved UDVA of 20/40 or better, and 80.0% of LASIK Xtra eyes achieved UDVA of 20/20 or better, compared to 66.0% of LASIK only eyes (p = 0.115). Efficacy indices were 0.99±0.17 for LASIK Xtra and 0.94±0.17 for LASIK only (p = 0.164). The proportion of eyes within ±0.50 D of attempted correction was 84% in the LASIK only group and 72% in the LASIK Xtra group at post-operative 3 months (p = 0.148). Safety indices were 1.11±0.19 and 1.11±0.18 in the LASIK Xtra and LASIK only groups, respectively (p = 0.735). Conclusion: LASIK Xtra achieved comparable safety, predictability and efficacy as LASIK in patients with high myopia. Good refractive stability was attained at 6-12 months. Further long term studies are required to determine whether simultaneous CXL is able to reduce postoperative LASIK keratectasia in high-risk individuals.
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12

Fatima, Khushbu, Zahid Saddique, Syed Nishat Akram, and Aamir Furqan. "LASIK;." Professional Medical Journal 24, no. 02 (February 14, 2017): 293–95. http://dx.doi.org/10.29309/tpmj/2017.24.02.519.

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Objectives: To determine the effect of LASIK on tear film stability. Study Design:Cross sectional, prospective study. Setting: The study was conducted in D. G. Laser Vision andDiagnostic Center, D.G. Khan, South Punjab, Pakistan. Period: From March 2016 to September2016. Materials and Methods: One hundred patients (two hundred eyes) were selected forthis study. SPSS version 20 was used to analyze the data. Categorical variables presented asfrequency and percentages and numerical variables presented as mean ± standard deviation.Results: It is observed that values of tear break up time, Schimer I and Schimer II were decreasingat one week and one month post LASIK as compare to one week pre LASIK values. Mean tearbreak up time at one week of pre LASIK was 14.72 ± 1.08 seconds (P=0.000), at one week postLASIK was 13.64 ± 1.507 seconds (P=0.000) and at one month post LASIK was 13.02 ± 1.695seconds (P=0.000). Conclusion: Laser in situ keratomileusis (LASIK) significantly changestear film stability and tear secretions for at least one month post operatively.
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13

Bonita Asyigah and Ani Ismail. "Accommodation Amplitude Before and After Laser In Situ Keratomiletus (LASIK) In Myopic Patients." Sriwijaya Journal of Ophthalmology 3, no. 1 (June 20, 2020): 1–18. http://dx.doi.org/10.37275/sjo.v3i1.43.

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ABSTRACT Introductions: Laser in situ Keratomileusis (LASIK) is the most common refractive surgery to treat myopia. One of the most common complain after this procedure is blurry near- vision. Objectives: To evaluate the role of accommodation amplitude (AA) in myopic patients before and after LASIK and its effect to blurry near-vision in myopic patients after LASIK Methods: Patients with myopia who underwent LASIK procedure in Sriwijaya Eye Center Hospital from January to February 2018 studied prospectively. AA was assessed before and after LASIK with 1 day, 1 week and 1 month. Myopia degree, intraocular pressure (IOP), age, gender, ablation and corneal profile were also assessed. Results: A total 52 eyes from 32 patients were included. Visual acuity (VA) of all sample were significantly improve in 1 day after LASIK (p 0,001). Mean AA in myopic patients before LASIK 9,25 D and AA 1 day after LASIK were all significantly decrease into 9,00D (p 0,012) which can cause in blurry near- vision after LASIK. In 1 month followed-up, mean AA is significantly improved into 11,00 D (p 0,000) with no complain. Other factor that affect the changing AA were corneal cell density (CD), IOP and AA before LASIK. Conclusions: There is significant AA difference in myopic patients before and after LASIK. Blurry near-vision after LASIK is caused by AA adaptation mechanism after LASIK.
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14

Ambrósio, Renato, and Steven Wilson. "LASIK vs LASEK vs PRK: Advantages and indications." Seminars in Ophthalmology 18, no. 1 (March 1, 2003): 2–10. http://dx.doi.org/10.1080/08820530390897738.

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15

Ambrósio, Renato, and Steven E. Wilson. "LASIK vs LASEK vs PRK: Advantages and indications." Seminars in Ophthalmology 18, no. 1 (January 2003): 2–10. http://dx.doi.org/10.1076/soph.18.1.2.14074.

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16

Zhao, Li-Quan, and Huang Zhu. "Contrast Sensitivity after Zyoptix Tissue Saving LASIK and Standard LASIK for Myopia with 6-Month Followup." Journal of Ophthalmology 2011 (2011): 1–6. http://dx.doi.org/10.1155/2011/839371.

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This control-matched comparative study evaluated changes in contrast sensitivity after Zyoptix tissue-saving (TS) LASIK and Planoscan standard LASIK (Technolas 217z, Bausch & Lomb) for myopia 6 months postoperatively. 102 TS LASIK-treated eyes were matched with 102 standard LASIK-treated eyes (divided into low, moderate, and high groups). There were no significant differences in refraction outcomes between the groups postoperatively. In high group, a significant reduction in contrast sensitivity after TS LASIK was found at high spatial frequencies (P<.05) under photopic conditions and at middle to high spatial frequencies (P<.05) under mesopic conditions. And significant reduction was also found in standard LASIK at high spatial frequency (P<.05) under mesopic conditions. The reduction was significantly lower in TS LASIK than that in standard LASIK at high spatial frequencies (P<.05) under mesopic conditions. TS LASIK was prone to reduce mesopic contrast sensitivity of high myopia at high spatial frequencies.
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17

Wilson, Steven E. "LASIK." Cornea 17, no. 5 (September 1998): 459–67. http://dx.doi.org/10.1097/00003226-199809000-00001.

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18

Lawless, Michael, and Christopher Hodge. "LASIK." International Ophthalmology Clinics 53, no. 1 (2013): 111–28. http://dx.doi.org/10.1097/iio.0b013e318271346e.

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19

Tang, Maolong, Yan Li, and David Huang. "Corneal Epithelial Remodeling after LASIK Measured by Fourier-Domain Optical Coherence Tomography." Journal of Ophthalmology 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/860313.

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Purpose. To quantify corneal epithelial thickness changes after myopic LASIK by OCT.Methods.Epithelial thickness before and after myopic LASIK were measured by a Fourier-domain OCT system. Average central (within 1 mm diameter) and paracentral epithelial thickness (5~6 mm diameter) before and after LASIK were compared. Correlation between central epithelial thickness change and laser spherical equivalent setting was evaluated. An epithelial smoothing constant was estimated based on a mathematical model published previously.Results.Nineteen eyes from 11 subjects were included in the study. Eyes had myopic LASIK ranging from −1.69 D to −6.75 D spherical equivalent. The average central epithelial thickness was 52.6 ± 4.1 μm before LASIK and 56.2 ± 4.3 μm 3 months after LASIK (p=0.002). The average paracentral epithelial thickness was 51.6 ± 6.6 μm before LASIK and 54.8 ± 4.3 μm 3 months after LASIK (p=0.007). The change in average central epithelial thickness was correlated with laser spherical equivalent (R2= 0.40,p=0.028). The epithelial smoothing constant was estimated to be 0.46 mm.Conclusions. Corneal epithelial thickens centrally and paracentrally after myopic LASIK. The extent of epithelial remodeling correlated with the amount of LASIK correction and could be predicted by a mathematical model.
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20

Toth, Cynthia A., Ramin Mostafavi, Sharon Fekrat, Cynthia A. Toth, and Terry Kim. "LASIK and vitreous pathology after LASIK." Ophthalmology 109, no. 4 (April 2002): 624. http://dx.doi.org/10.1016/s0161-6420(02)00996-x.

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21

M, Hosny. "Comparing Corneal OCT Findings in High Irradiance Corneal Crosslinking Combined with Femtosecond Laser In Situ Keratomileusis versus Femtosecond Laser In Situ Keratomileusis." Open Access Journal of Ophthalmology 6, no. 1 (January 4, 2021): 1–12. http://dx.doi.org/10.23880/oajo-16000209.

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Objective: To study Corneal OCT findings in the interface and the demarcation line under or over the interface in patients that undergo Femtosecond laser in situ Keratomeulisis compared to patients that undergo Femtosecond laser in situ Keratomeulisis combined with high irradiance corneal cross linking (Femto-Lasik Xtra). Study Design: Prospective Randomized Comparative Study. Methods: Our study included 40 eyes of 20 patients divided into 2 groups, a group of 10 patients with 20 eyes underwent Femto-Lasik & the other group of 10 patients of 20 eyes underwent Femto-Lasik Xtra. The Femto Lasik procedure was done using Alcon Wave Light FS200 laser machine. The Femto-Lasik XTRA procedure entails the administration of half fluence high irradiance cross-linking subsequent to refractive correction. A higher concentration 0.25% riboflavin is applied on the stromal bed and the flap subsequent to laser ablation with a soak time of 90 seconds, UV-A irradiance is delivered as a homogenous beam of 30 mW/cm2 for 90 s to deliver a total fluence of 2.7J/cm2. Patients were randomly observed and HEIDELBERG ASOCT was performed after 1 week, 1 month & 3 months post-operative. Results: A demarcation line was noted in femto Lasik Xtra patients, appeared more evident in the peripheral cornea and faded as it approached the central cornea. It became less evident after 1 month and 3 months period respectively. Also the flap hinge was more hyper reflective and evident in femto Lasik Xtra patients when compared to femto Lasik patients. Anterior crosslinked stroma appeared more hyper reflective than posterior stroma in femto Lasik Xtra patients. Flap edge was also more hyper reflective and better demarked in femto Lasik Xtra treated corneas when compared to femto Lasik treated corneas. Conclusion: AS-OCT showed significant differences between femto Lasik and Femto Lasik Xtra treated corneas. Significant changes were noted in the demarcation line in Femto Lasik Xtra patients along different time periods post-operative.
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Wu, Ying, Lei Tian, Li-qiang Wang, and Yi-fei Huang. "Efficacy and Safety of LASIK Combined with Accelerated Corneal Collagen Cross-Linking for Myopia: Six-Month Study." BioMed Research International 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/5083069.

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This was a prospective controlled clinical trial. 48 myopia patients (96 eyes) were included in this study. After LASIK, accelerated corneal collagen cross-linking (ACXL) was used for myopia treatment. During 6-month follow-up, the results of LASIK-ACXL treatment were studied and compared to the LASIK-only procedure. The results showed that no statistically significant differences in UDVA, CDVA, MRSE,Kmean, pachymetry, or ECD were found between the two groups at the visit after 6 months of follow-up (allP>0.05). At 6 months postoperatively, 2 eyes lost one or more lines of visual acuity in the LASIK-ACXL group, whereas all LASIK-only treated eyes had a stable CDVA.In vivoconfocal microscopy showed a decrease of keratocyte density and appearance of honeycomb-like structures in the anterior residual stroma bed; the changes were similar but more pronounced following LASIK-only. None of the cases in both groups developed signs of significant keratitis, regression, or ectasia during the 6-month follow-up. LASIK-ACXL can effectively correct refractive error in patients with myopia, with no significant complications during 6-month follow-up, indicating stability and morphologic change similar to those with LASIK-only treatment.
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Oh, Dominique Clare, Yiong Huak Chan, Sao Bing Lee, and Jovina Li Shuen See. "Prophylactic corneal cross-linking in LASIK surgery: effects on visual outcome and recovery time." Asian Journal of Ophthalmology 17, no. 1 (January 17, 2020): 61–68. http://dx.doi.org/10.35119/asjoo.v17i1.451.

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Introduction: Collagen cross-linking is a useful adjunct in preventing corneal ectasia after laser-assisted in situ keratomileusis (LASIK). This study aimed to evaluate whether prophylactic cross-linking in IntraLase LASIK affects optimum visual outcome and recovery time in the immediate post-surgery period and is associated with any side effects. Methods: This was a retrospective case study on the right eyes of 100 Chinese subjects aged 18 to 40 years who underwent IntraLase LASIK. Fifty subjects who underwentcross-linking after completing LASIK (Group A) were compared with 50 subjects who did not undergo LASIK (Group B). Cases were evaluated for pre- and post-operative spherical equivalent, uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), recovery time and presence of side effects. Results: At 1 week post-LASIK, mean (SD) UDVA of Group A subjects was poorer than Group B, at 1.05 (0.19) vs 1.17 (0.19) (p = 0.036); however, there was no significant difference in CDVA (p = 0.095). By 1 month post-LASIK, differences in both UDVA and CDVA were insignificant (p = 0.055, 0.106, respectively). Mean recovery time was 2.72 (95% confidence interval [CI] = 0.64-4.7) days longer in Group A (p = 0.010), although by 1 month post-LASIK, both groups were able to achieve CDVA equal to or better than that achieved pre-LASIK. Incidence of mild inflammation and dry eyes post-LASIK was similar in both groups (p = 1.00, 0.749, respectively); no other complications were observed. Conclusion: No differences in visual outcomes at and occurrence of side effects at 1 month post-LASIK were observed between subjects who underwent cross-linking prior to refractive surgery and those who did not. However, the group that underwent cross-linking had a slightly longer mean recovery time. Our study supports prophylactic cross-linking as a safe procedure that does not affect immediate visual outcomes among the Chinese population when used in adjunct with LASIK surgery.
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Kohnen, Thomas, and Gernot Steinwender. "LASIK und Femto-LASIK 2019: eine Standortbestimmung." Spektrum der Augenheilkunde 33, no. 6 (September 9, 2019): 139–46. http://dx.doi.org/10.1007/s00717-019-00437-2.

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TEUS, MIGUEL A., LAURA DE BENITO-LLOPIS, and JOSE M. S??NCHEZ-PINA. "LASEK Versus LASIK for the Correction of Moderate Myopia." Optometry and Vision Science 84, no. 7 (July 2007): 605–10. http://dx.doi.org/10.1097/opx.0b013e3180dc9a4f.

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26

Spadea, Leopoldo, Francesca Verboschi, Stefano Valente, and Enzo Maria Vingolo. "Corneal Collagen Crosslinking for Keratectasia after Laser in situ Keratomileusis: A Review of the Literature." International Journal of Keratoconus and Ectatic Corneal Diseases 2, no. 3 (2013): 113–20. http://dx.doi.org/10.5005/jp-journals-10025-1063.

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ABSTRACT Corneal ectasia is a serious vision-threatening complication of laser in situ keratomileusis (LASIK). It is associated with progressive corneal steepening, an increase in myopia and astigmatism, and decrease in uncorrected visual acuity. Before LASIK presence of risk factors (corneal thickness, refractive error, presence of clinical and subclinical corneal pathologies) should be studied so patients should be risk-stratified. Forme fruste keratoconus or marginal pellucid degeneration should be investigated before LASIK in order to inform the patients of the possibility to develop a corneal complication. Management of post-LASIK ectasia enlists crosslinking, INTACTS, contact lenses and, in the most serious cases, lamellar keratoplasty and corneal transplantation. Crosslinking is a technique to treat and even prevent post-LASIK corneal ectasia. LASIK is a technique that reduces the corneal strength and stability. Crosslinking increases the number of collagen interfibrillar covalent bonds, using ultraviolet A and riboflavin. This result increases stability in corneal strength, reducing the risk to develop corneal ectasia (if performed simultaneously with LASIK) or it treats ectasia (if performed after LASIK keratectasia). How to cite this article Spadea L, Verboschi F, Valente S, Vingolo EM. Corneal Collagen Crosslinking for Keratectasia after Laser in situ Keratomileusis: A Review of the Literature. J Kerat Ect Cor Dis 2013;2(3):113-120.
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Hoffmann, E. M., H. B. Dick, F. H. Grus, and N. Pfeiffer. "Scanning Laser Polarimetry and Retinal Thickness Analysis before and after Laser in Situ Keratomileusis." European Journal of Ophthalmology 15, no. 4 (July 2005): 434–40. http://dx.doi.org/10.1177/112067210501500402.

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Purpose To evaluate changes in retinal nerve fiber layer (RNFL) thickness after laserin situ keratomileusis (LASIK) using a scanning laser Polarimeter with fixed corneal compensation (GDx) and the retinal thickness analyzer (RIA). Methods Thirty-eight eyes of 19 healthy subjects (10 female and 9 male; mean age 37.0±8.8 years) underwent GDx and RTA measurements before and after LASIK. All subjects revealed mild to high myopia (mean spherical refraction: −4.0±2.75 D). Measurements using GDx were followed by RTA measurements after pupil dilation. All measurements were performed the day before LASIK and 1 week postoperatively. Results GDX revealed a decrease in nerve fiber layer thickness measurements after LASIK, but did not reach statistical significance (p>0.05). Using RTA, mean RNFL thickness (MRNFL) and RNFL cross sectional area decreased significantly after LASIK (p=0.03 and p=0.02, respectively). Conclusions Scanning laser polarimetry revealed a slight decrease in RNFL thickness measurements after LASIK. MRNFL and RNFL cross section were significantly lower after LASIK using RTA. The changes might be artifacts in a small group of myopic subjects.
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28

Gui, Xiao, Sha Li, Na Zhao, Hao-Rui Zhang, Yu-Kun Zhou, Chen-Yang Huan, Chun-Yan Zhao, et al. "Comparative analysis of the clinical outcomes between wavefront-guided and conventional femtosecond LASIK in myopia and myopia astigmatism." International Journal of Ophthalmology 14, no. 10 (October 18, 2021): 1581–88. http://dx.doi.org/10.18240/ijo.2021.10.16.

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AIM: To compare the clinical outcomes of wavefront guided femtosecond LASIK (WFG LASIK) and conventional femtosecond LASIK (NWFG LASIK) in eyes with myopia and myopia astigmatism. METHODS: This was a retrospective, nonrandomized, comparative investigation enrolling 236 eyes of 122 patients (18-50y) with low & moderate and high myopia. The WFG group including 97 eyes (50 patients) undergone WFG LASIK and the NWFG group including 139 eyes (72 patients) undergone conventional LASIK. Mean efficacy index, high order aberrations (HOAs), pupil size and the quality of visual questionnaire were evaluated 6mo postoperatively. RESULTS: There is no difference between WFG group (-0.054±0.049 in logMAR) and NWFG group (-0.040±0.056) in uncorrected distance visual acuity (UDVA) postoperatively. The myopia astigmatism is higher in WFG group than that in NWFG group (P<0.05). However, the mean efficacy index (MEI) in the WFG group (1.09±0.106) is better than that in the NWFG group (1.036±0.124; P<0.001). Increased HOAs were observed in NWFG group (0.30±0.196) than that in WFG group (0.146±0.188; P<0.001). The pupil size is larger in WFG group (5.15±0.76 mm) than that in NWFG group (4.32±0.52 mm). The patients are satisfied with the clinical surgery, yet WFG group showed better visual quality using the questionnaire survey. Meanwhile, high myopia would result in worse MEI, HOAs and visual quality than low & moderate myopia. CONCLUSION: WFG and NWFG FS-LASIK are both effective and safe procedures to correct low & moderate and high myopia, but WFG FS-LASIK gives a better postoperative MEI, aberrometric control and predictable outcome. Meanwhile, WFG FS-LASIK is better than NWFG FS-LASIK in correction of myopia astigmatism. Low & moderate myopia allow better clinical outcomes than high myopia using any surgical method.
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29

Moshirfar, Majid, Noor F. Basharat, Nour Bundogji, Emilie L. Ungricht, Ines M. Darquea, Matthew E. Conley, Yasmyne C. Ronquillo, and Phillip C. Hoopes. "Laser-Assisted In Situ Keratomileusis (LASIK) Enhancement for Residual Refractive Error after Primary LASIK." Journal of Clinical Medicine 11, no. 16 (August 18, 2022): 4832. http://dx.doi.org/10.3390/jcm11164832.

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Background: To evaluate the safety, efficacy, and predictability of laser-assisted in situ keratomileusis (LASIK) enhancement after primary LASIK and compare to Food and Drug Administration (FDA) criteria. Methods: Patients who underwent LASIK enhancement after primary LASIK between 2002 and 2019 were compared to those who underwent LASIK without retreatment. Patient demographics, preoperative characteristics, visual outcomes, and postoperative complications were compared between groups. Epithelial ingrowth (EI) development was stratified based on duration between primary and secondary procedures. Results: We compared 901 eyes with LASIK enhancement to 1127 eyes without retreatment. Age, sex, surgical eye, sphere, cylinder, and spherical equivalent (SE) were significantly different between groups (p < 0.05). At 12 months post-enhancement, 86% of the eyes had an uncorrected distance visual acuity of 20/20 or better and 93% of eyes were within ±0.50 D of the target. Development of EI (6.1%) demonstrated an odds ratio of 16.3 in the long-term compared to the short-term (95% CI: 5.9 to 45.18; p < 0.0001). Conclusions: Older age at primary LASIK, female sex, right eye, and larger sphere, cylinder and SE were risk factors for enhancement. Risk of EI significantly increased when duration between primary and enhancement procedures exceeded five years. LASIK enhancements produce favorable outcomes and meet FDA benchmarks for safety, efficacy, and predictability.
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Bikbova, Guzel, Toshiyuki Oshitari, Madoka Sakurai, Takayuki Baba, and Shuichi Yamamoto. "Macular Hole after Laser In Situ Keratomileusis in a 26-Year-Old Patient." Case Reports in Ophthalmological Medicine 2013 (2013): 1–3. http://dx.doi.org/10.1155/2013/739474.

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The purpose of this study is to describe the 26-year-old patient with developed macular hole after bilateral laser in situ keratomileusis (LASIK). A macular hole with sharp margins and irregular surface of surrounding retina appeared in the left eye of the female 26-year-old patient two months after LASIK for correction of myopia (followup of 6 months). Although the best corrected visual acuity (BCVA) after LASIK was 1.0, after the macular hole has developed BCVA became 0.5. After surgery, the final visual acuity recovered to 0.7. Macular hole may develop after LASIK for myopia correction due to unknown changes of vitreoretinal interface. Complete informed consent must be obtained from patients with high myopic eyes before LASIK.
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31

Valbon, Bruno Freitas, Juliana Glicéria, Rodrigo Santos, and Milton Ruiz Alves. "Unilateral Corneal Ectasia after Bilateral LASIK: The Thick Flap Counts." International Journal of Keratoconus and Ectatic Corneal Diseases 2, no. 2 (2013): 79–83. http://dx.doi.org/10.5005/jp-journals-10025-1056.

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ABSTRACT Purpose To report a case of post-LASIK corneal ectasia due to a thick flap, while the contralateral eye did not develop ectasia after an incomplete deep flap cut, followed by a thinner flap LASIK procedure. Methods Case report Results This 45 years old female patient had bilateral myopic LASIK in 1999. Preoperative anterior curvature map was regular with no signs of keratoconus. Central keratometry was 42.88 × 44.70 @ 163 in OD and 43.43 × 45.24 @ 175 in OS. Ultrasound central corneal thickness was 586 μm and 619 μm in the right eye and left eye, respectively. Corneal OCT identified a deep meniscus-shaped LASIK flap, with a central thickness of a 392 μm in the right eye, and an incomplete deep peripheral cut in the left eye with a thinner meniscus-shaped LASIK flap. Conclusion Unilateral ectasia after LASIK may occur due to a thick flap which leads to biomechanical failure of the cornea. How to cite this article Valbon BF, Ambrosio R Jr, Glicéria J, Santos R, Luz A, Alves MR. Unilateral Corneal Ectasia after Bilateral LASIK: The Thick Flap Counts. Int J Kerat Ect Cor Dis 2013;2(2):79-83.
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32

Seven, Ibrahim, Joshua S. Lloyd, and William J. Dupps. "Differences in Simulated Refractive Outcomes of Photorefractive Keratectomy (PRK) and Laser In-Situ Keratomileusis (LASIK) for Myopia in Same-Eye Virtual Trials." International Journal of Environmental Research and Public Health 17, no. 1 (December 31, 2019): 287. http://dx.doi.org/10.3390/ijerph17010287.

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The use of computational mechanics for assessing the structural and optical consequences of corneal refractive procedures is increasing. In practice, surgeons who elect to perform PRK rather than LASIK must often reduce the programmed refractive treatment magnitude to avoid overcorrection of myopia. Building on a recent clinical validation study of finite element analysis (FEA)-based predictions of LASIK outcomes, this study compares predicted responses in the validated LASIK cases to theoretical PRK treatments for the same refractive error. Simulations in 20 eyes demonstrated that PRK resulted in a mean overcorrection of 0.17 ± 0.10 D relative to LASIK and that the magnitude of overcorrection increased as a function of attempted correction. This difference in correction closely matched (within 0.06 ± 0.03 D) observed differences in PRK and LASIK from a historical nomogram incorporating thousands of cases. The surgically induced corneal strain was higher in LASIK than PRK and resulted in more forward displacement of the central stroma and, consequently, less relative flattening in LASIK. This FE model provides structural confirmation of a mechanism of action for the difference in refractive outcomes of these two keratorefractive techniques, and the results were in agreement with empirical clinical data.
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33

Davis, Elizabeth A., David R. Hardten, and Richard L. Lindstrom. "LASIK Complications." International Ophthalmology Clinics 40, no. 3 (2000): 67–75. http://dx.doi.org/10.1097/00004397-200007000-00009.

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34

Durrie, Daniel S., and Trent L. Vande Garde. "LASIK Enhancements." International Ophthalmology Clinics 40, no. 3 (2000): 103–10. http://dx.doi.org/10.1097/00004397-200007000-00013.

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35

Knorz, Michael C. "TopoLink LASIK." International Ophthalmology Clinics 40, no. 3 (2000): 145–49. http://dx.doi.org/10.1097/00004397-200007000-00017.

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36

Estopinal, Christopher B., and Shahzad I. Mian. "LASIK Flap." International Ophthalmology Clinics 56, no. 2 (2016): 67–81. http://dx.doi.org/10.1097/iio.0000000000000107.

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37

Rosen, Emanuel S. "LASIK mania." Journal of Cataract & Refractive Surgery 26, no. 3 (March 2000): 303–4. http://dx.doi.org/10.1016/s0886-3350(00)00344-8.

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38

Dada, Tanuj. "Secondary LASIK." Journal of Cataract & Refractive Surgery 28, no. 2 (February 2002): 205. http://dx.doi.org/10.1016/s0886-3350(01)01335-9.

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39

Agarwal, Amar. "Secondary LASIK." Journal of Cataract & Refractive Surgery 28, no. 2 (February 2002): 205. http://dx.doi.org/10.1016/s0886-3350(01)01336-0.

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40

Lam, Dennis S. C., Arthur C. K. Cheng, and Alfred T. S. Leung. "LASIK complications1." Ophthalmology 106, no. 8 (August 1, 1999): 1455–56. http://dx.doi.org/10.1016/s0161-6420(99)90474-8.

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41

Gulani, Arun C. "LASIK complications." Ophthalmology 106, no. 8 (August 1, 1999): 1457. http://dx.doi.org/10.1016/s0161-6420(99)90476-1.

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42

Wilson, Theresa Supik. "LASIK Surgery." AORN Journal 71, no. 5 (May 2000): 960–83. http://dx.doi.org/10.1016/s0001-2092(06)61547-0.

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43

Melki, Samir A., and Dimitri T. Azar. "LASIK Complications." Survey of Ophthalmology 46, no. 2 (September 2001): 95–116. http://dx.doi.org/10.1016/s0039-6257(01)00254-5.

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44

Davis, Elizabeth A., David R. Hardten, Michelle Lindstrom, Thomas W. Samuelson, and Richard L. Lindstrom. "Lasik enhancements." Ophthalmology 109, no. 12 (December 2002): 2308–13. http://dx.doi.org/10.1016/s0161-6420(02)01245-9.

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45

Packer, Samuel. "LASIK reporting:." Journal of Cataract & Refractive Surgery 30, no. 8 (August 2004): 1609–10. http://dx.doi.org/10.1016/j.jcrs.2004.06.016.

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46

&NA;. "LASIK “DRY EYE”: LASIK-INDUCED NEUROTROPHIC EPITHELIOPATHY (LNE)." Cornea 20, no. 7 (October 2001): 780. http://dx.doi.org/10.1097/00003226-200110000-00040.

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47

Dhaliwal, Deepinder K. "Practical Advanced LASIK Skills and Advanced LASIK Technology." Cornea 21, no. 6 (August 2002): 635. http://dx.doi.org/10.1097/00003226-200208000-00030.

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48

Taneri, Suphi. "Epi-LASIK After Amputation of a LASIK Flap." Journal of Refractive Surgery 22, no. 6 (June 1, 2006): 613–16. http://dx.doi.org/10.3928/1081-597x-20060601-16.

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49

Chou, Chien-Chih, Po-Jen Shih, Hung-Chou Lin, Jun-Peng Chen, Jia-Yush Yen, and I.-Jong Wang. "Changes in Intraocular Pressure after Transepithelial Photorefractive Keratectomy and Femtosecond Laser In Situ Keratomileusis." Journal of Ophthalmology 2021 (March 10, 2021): 1–10. http://dx.doi.org/10.1155/2021/5592195.

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Purpose. To investigate the changes in intraocular pressure (IOP) and biomechanically corrected IOP (bIOP) in patients undergoing transepithelial photorefractive keratectomy (TPRK) and femtosecond laser in situ keratomileusis (FS-LASIK) and to determine the effects of preoperative biomechanical factors on IOP and bIOP changes after FS-LASIK and TPRK. Design. A retrospective comparative study. Methods. We retrospectively investigated the IOP and corneal biomechanical changes in 93 eyes undergoing FS-LASIK and 104 eyes undergoing TPRK in a clinical setting. Preoperative and postoperative data on ophthalmic and Corvis ST examinations, in vivo Young’s modulus, and noncontact tonometry were analyzed. Marginal linear regression models with generalized estimating equations were used for intragroup and intergroup comparisons of IOP and bIOP changes. Results. In the univariate model, IOP reduction after FS-LASIK was 2.49 mmHg higher than that after TPRK. In addition, bIOP reduction after FS-LASIK was 1.85 mmHg higher than that after TPRK. In the multiple regression model, we revealed that IOP reduction after FS-LASIK was 1.75 mmHg higher than that after TPRK. Additionally, bIOP reduction after FS-LASIK was 1.64 mmHg higher than that after TPRK. Postoperative changes in bIOP were less than those in IOP. In addition, Young’s modulus and CBI had no significant effect on postoperative IOP and bIOP changes. We establish a biomechanically predictive model using the available data to predict postoperative IOP and bIOP changes after TPRK and FS-LASIK. Conclusions. Reductions in IOP and bIOP after FS-LASIK were 1.75 mmHg and 1.64 mmHg, respectively, more than those after TPRK, after adjustment for confounders. We revealed that the type of refractive surgery and peak distance (PD) were significant predictors of postoperative IOP and bIOP changes. By contrast, depth of ablation showed a significant effect on only IOP changes.
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Jiang, Zheng, Dong-Qiang Luo, and Jiao Chen. "Optical and visual quality comparison of implantable collamer lens and femtosecond laser assisted laser in situ keratomileusis for high myopia correction." International Journal of Ophthalmology 14, no. 5 (May 18, 2021): 737–43. http://dx.doi.org/10.18240/ijo.2021.05.15.

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AIM: To compare clinical outcomes and refractive stability of implantable collamer lens (ICL) implantation and femtosecond laser assisted laser in situ keratomileusis (FS-LASIK) for high myopia correction. METHODS: The Optical Quality Analysis System (OQAS) was used to evaluate clinical outcomes objectively after operation for high myopia correction. We compared the two procedures in terms of 1-year changes in uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), safety index, efficacy index, spherical equivalent, modulation transfer function (MTF) cutoff frequency, strehl ratio (SR) and objective scatter index (OSI). RESULTS: At 1y postoperatively, the safety indices were 1.33±0.27 in ICL group, and 1.17±0.24 in FS-LASIK group. 39.58% in the ICL group and 27.59% in the FS-LASIK group gained CDVA in 2 lines or better than that in preoperative CDVA. The efficacy indices were 1.28±0.22 in ICL group, and 1.13±0.26 in FS-LASIK group. The changes of spherical equivalent from 1wk to 1y postoperatively was -0.12±0.37 D in ICL group, and -0.79±0.58 D in FS-LASIK group (P&#x003C;0.05). Spherical equivalent within ±0.50 D was achieved in 97.92% in ICL group and 68.97% in FS-LASIK group. MTF cutoff frequency were higher with ICL as compared to FS-LASIK (P&#x003C;0.05) at each postoperative follow-up stage; for postoperative 1mo later, SR was statistically significant difference between two groups (P&#x003C;0.05); with no statistically significant difference in OSI between two groups (P&#x003E;0.05) in postoperative 3mo later. CONCLUSION: ICL implantation and FS-LASIK procedures both provide good safety and predictability in high myopia correction. ICL implantation provides better clinical outcomes and refractive stability than FS-LASIK.
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