Academic literature on the topic 'Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)'

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Journal articles on the topic "Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)"

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Scheffler, G. L., and D. Pozebon. "Advantages, drawbacks and applications of mixed Ar–N2 sources in inductively coupled plasma-based techniques: an overview." Anal. Methods 6, no. 16 (2014): 6170–82. http://dx.doi.org/10.1039/c4ay00178h.

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This review deals with mixed gas Ar–N2 plasmas, highlighting advantages, limitations and applications of them in inductively coupled plasma optical emission spectrometry (ICP OES), inductively coupled plasma mass spectrometry (ICP-MS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) techniques, covering publications in the last three decades.
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Luo, Wenhe, Tao Li, Meng Wang, Wanqin Dai, Chunlei Jiao, Yuhui Ma, Yayun Ding, Fang Yang, Xiao He, and Zhiyong Zhang. "Nanoparticles Determination by Laser Ablation Inductively Coupled Plasma Mass Spectrometry." Journal of Nanoscience and Nanotechnology 21, no. 11 (November 1, 2021): 5436–42. http://dx.doi.org/10.1166/jnn.2021.19476.

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Quantitatively studying the biodistribution and transformation of nanomaterials is of great importance for nanotoxicological evaluation. Recently, laser ablation inductively coupled plasma mass spectrometry has been employed to distinguish nanoparticles (NPs) with their dissolved ions in biological samples. The principle of the proposal is based on a hypothesis that the intact NPs sampled by laser ablation will generate discrete sharp pulses of signals in ICP-MS measurement, being totally different from the continuous, relatively lower signals generated by ions. However, it is still a controversy whether NPs could maintain their intactness during the laser ablation. This work found a way to exactly determine the number of NPs sampled for each LA-ICP-MS measurement. It made possible to reveal the signal profile of a single NP in LA-ICP-MS analysis. The results suggest that AuNR, AgNP and TIO2 NP were broken into much smaller secondary NPs during the laser ablation, therefore generating continuous signals in the analyzer. There was a certain probability that the fragmentation of large-sized NP or multiple NPs by laser ablation was not sufficient, leaving some NPs unbroken or some secondary NPs with relatively large sizes to generate discrete pulses of signals in the analyzer. When the intactness of NPs during laser ablation cannot be assured, it is impossible to determine the attribution of mass spectrum signals. These findings compromise the reliability of distinguishing NPs from their dissolved ions by LA-ICP-MS.
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Neff, Christoph, Pascal Becker, Bodo Hattendorf, and Detlef Günther. "LA-ICP-MS using a nitrogen plasma source." Journal of Analytical Atomic Spectrometry 36, no. 8 (2021): 1750–57. http://dx.doi.org/10.1039/d1ja00205h.

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Castellanos-Garcia, Laura J., Kristen N. Sikora, Jeerapat Doungchawee, and Richard W. Vachet. "LA-ICP-MS and MALDI-MS image registration for correlating nanomaterial biodistributions and their biochemical effects." Analyst 146, no. 24 (2021): 7720–29. http://dx.doi.org/10.1039/d1an01783g.

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Laser ablation inductively-coupled plasma mass spectrometry (LA-ICP-MS) imaging and matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) can measure distributions of elements and biomolecules in tissue sections.
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Petibon, Caroline M., Henry P. Longerich, Ingo Horn, and Mike N. Tubrett. "Neon Inductively Coupled Plasma for Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry." Applied Spectroscopy 56, no. 5 (May 2002): 658–64. http://dx.doi.org/10.1366/0003702021955231.

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The use of a neon inductively coupled plasma (Ne ICP) in place of an argon inductively coupled plasma (Ar ICP) for laser ablation microprobe-inductively coupled plasma-mass spectrometry (LAM-ICP-MS) is demonstrated. Gas blank mass spectra were obtained comparing the signals obtained with an Ar ICP with the Ne ICP. Sensitivity (signal/concentration) data were also obtained for a number of analytes using solid reference materials. The sensitivity data is complicated by significant changes in optimum Ne ICP parameters (especially nebulizer gas flow) for analytes of varying mass. The sensitivity of the Ne ICP is in general also lower than that obtained for the Ar ICP. The potential for the Ne ICP to reduce the formation of argides, both in the background and from sample induced interferences, is demonstrated. Clearly shown is the reduction of the interferences of 63Cu40Ar and 65Cu40Ar on 103Rh and 105Pd in a Cu2S sample, as well as the reduction of the interferences of 58Ni40Ar and 60Ni40Ar on 98Ru and 100Ru in a NiS sample.
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Miliszkiewicz, Natalia, Stanisław Walas, and Anna Tobiasz. "Current approaches to calibration of LA-ICP-MS analysis." Journal of Analytical Atomic Spectrometry 30, no. 2 (2015): 327–38. http://dx.doi.org/10.1039/c4ja00325j.

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For solid sample quantitative analysis by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) the main analytical problems are adequate standards preparation and signals standardization.
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Faltusová, Veronika, Tomáš Vaculovič, Markéta Holá, and Viktor Kanický. "Ilaps – python software for data reduction and imaging with LA-ICP-MS." Journal of Analytical Atomic Spectrometry 37, no. 4 (2022): 733–40. http://dx.doi.org/10.1039/d1ja00383f.

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In the past couple of years, laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has been widely used for trace element analysis in solid samples and the study of their distribution.
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Moreda-Piñeiro, Jorge, Alicia Cantarero-Roldán, Antonio Moreda-Piñeiro, José Ángel Cocho, and Pilar Bermejo-Barrera. "Laser ablation inductively coupled plasma mass spectrometry for multi-elemental determination in dried blood spots." Journal of Analytical Atomic Spectrometry 32, no. 8 (2017): 1500–1507. http://dx.doi.org/10.1039/c7ja00168a.

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Manard, Benjamin T., C. Derrick Quarles, E. Miller Wylie, and Ning Xu. "Laser ablation – inductively couple plasma – mass spectrometry/laser induced break down spectroscopy: a tandem technique for uranium particle characterization." Journal of Analytical Atomic Spectrometry 32, no. 9 (2017): 1680–87. http://dx.doi.org/10.1039/c7ja00102a.

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Laser ablation – inductively coupled plasma – mass spectrometry (LA-ICP-MS) in tandem with laser induced breakdown spectroscopy (LIBS) was employed to chemically map and characterize uranium particles.
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Pozebon, D., G. L. Scheffler, and V. L. Dressler. "Recent applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for biological sample analysis: a follow-up review." Journal of Analytical Atomic Spectrometry 32, no. 5 (2017): 890–919. http://dx.doi.org/10.1039/c7ja00026j.

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Dissertations / Theses on the topic "Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)"

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Castro, Waleska. "Elemental Analysis of Biological Matrices by Laser Ablation High Resolution Inductively Coupled Plasma Mass Spectrometry (LA-HR-ICP-MS) and High Resolution Inductively Coupled Plasma Mass Spectrometry (HR-ICP-MS)." FIU Digital Commons, 2008. http://digitalcommons.fiu.edu/etd/185.

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The need for elemental analysis of biological matrices such as bone, teeth, and plant matter for sourcing purposes has emerged within the forensic and geochemical laboratories. Trace elemental analyses for the comparison of aterials such as glass by inductively coupled plasma mass spectrometry (ICP-MS) and laser ablation ICP-MS has been shown to offer a high degree of discrimination between different manufacturing sources. Unit resolution ICP-MS instruments may suffer from some polyatomic interferences including 40Ar16O+, 40Ar16O1H+, and 40Ca16O+ that affect iron measurement at trace levels. Iron is an important element in the analysis of glass and also of interest for the analysis of several biological matrices. A comparison of the nalytical performance of two different ICP-MS systems for iron analysis in glass for determining the method detection limits (MDLs), accuracy, and precision of the measurement is presented. Acid digestion and laser ablation methods are also compared. Iron polyatomic interferences were reduced or resolved by using dynamic reaction cell and high resolution ICP-MS. MDLs as low as 0.03 ìg g-1 and 0.14 ìg g-1 for laser ablation and solution based analyses respectively were achieved. The use of helium as a carrier gas demonstrated improvement in the detection limits of both iron isotopes (56Fe and 57Fe) in medium resolution for the HR-ICP-MS and with a dynamic reaction cell (DRC) coupled to a quadrupole ICP-MS system. The development and application of robust analytical methods for the quantification of trace elements in biological matrices has lead to a better understanding of the potential utility of these measurements in forensic chemical analyses. Standard reference materials (SRMs) were used in the development of an analytical method using HR-ICP-MS and LA-HR-ICP-MS that was subsequently applied on the analysis of real samples. Bone, teeth and ashed marijuana samples were analyzed with the developed method. Elemental analysis of bone samples from 12 different individuals provided discrimination between individuals, when femur and humerus bones were considered separately. Discrimination of 14 teeth samples based on elemental composition was achieved with the exception of one case where samples from the same individual were not associated with each other. The discrimination of 49 different ashed plant (cannabis)samples was achieved using the developed method.
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Subedi, Kiran. "Elemental Analysis of Printing Inks Using Tandem Laser- Induced Breakdown Spectroscopy and Laser Ablation Inductively Coupled Plasma Mass Spectrometry." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2263.

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As a consequence of the widespread use of computers coupled to high-quality printers and different types of papers, forgery, counterfeiting, change of wills, anonymous letter writing and felonious use of the documents have become serious problems. Forensic analysts are always seeking methods that can provide reliable information on whether a specimen collected at the crime scene is linked to the crime or to a source of known origin. Sensitive methods that can provide more detailed characterization of natural or man-made materials or even provide information not previously available to forensic examiners. Recent advances in rapid solid sampling of materials using laser ablation (LA) coupled to inductively coupled plasma mass spectroscopy (ICP-MS) have led to this analytical method to be regarded as the “gold standard” in the field of elemental analysis for trace level components in solids. Another, emerging, analytical technique that uses the same laser pulse to generate a plasma that can be interrogated with spectroscopy is laser induced break down spectroscopy (LIBS). The analysis of ink and paper is also possible because of the surface removal effect of laser interactions with the samples. In the present study, printing inks were analyzed using LIBS, LA-ICP-MS and both of them in tandem mode. In the tandem setup, the light generated during the relaxation of the excited species (LIBS) was used to create a spectral signature of the elements, and the mass-to-charge ratio of the ejected particles (ICP-MS) was used to create a mass spectrum. For a set of 319 printing ink samples, LA-ICP-MS alone provided discrimination greater than 99%. A subset of 43 printing inks, having a very similar elemental profile, was analyzed by tandem LIBS/LA-ICP-MS. The fusion of LIBS and LA-ICP-MS provided additional discrimination through the detection of elements like Ca, Si, Fe, and K by LIBS, that are difficult to detect and confirm using standalone ICP-MS because of the spectral interferences (isobaric and polyatomic) involved. The combination of these two sensors was found to minimize the individual limitations and provide a more complete and representative chemical characterization of printing inks.
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Douglas, David N. "Development of a high speed, high efficiency LA-ICP-MS interface." Thesis, Loughborough University, 2013. https://dspace.lboro.ac.uk/2134/12164.

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Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) is now a well established analytical technique used to sample solid materials and determine their elemental composition. Two areas that are becoming increasingly important, and for which LA-ICP-MS is a key tool, are bio-imaging and the analysis of micro-particulates. However, current instrumental designs limit the practicality of the technique for these applications. This study investigates the development of a high speed, high efficiency LA-ICP-MS interface through modelling of the flow dynamics of a newly designed laser ablation cell and experimental investigation of single laser pulse response. Through this work the Sniffer-Dual Concentric Injector interface was realised. This interface reduced particle residence times within the laser cell and transport tubing. The interface was also used to investigate turbulence related aerosol dispersion within the ICP and potential designs to overcome this. The resulting design yields an interface with improved sensitivity and reduced aerosol dispersion such that a lower limit of detection is achieved, important when considering the mass of analyte in a single cell or micro-particulate, compared to existing designs. Thus the interface can be used to improve image spatial resolution as the ablation spot size, and thus pixel information, can be reduced; and also reduces total analysis time. The calibration technique Laser Ablation of a Sample In Liquid (LASIL) was also investigated as a means of calibration for solid samples. The investigation lead to the development of LASIL in a droplet, a technique that can be used to calibrate solid samples when a matrix matched standard is unavailable. The mechanism of the technique resulted in an improved laser-energy sample coupling efficiency and a reduction in the liquid to ablated mass ratio, thus decreasing sampling time. As the technique captures the ablated particulate in solution, post chemistry techniques can be used to remove analyte interferences.
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Gorishek, Emma Lee. "Laser Ablation Inductively Coupled Plasma Mass Spectrometry and Raman Spectroscopy Imaging of Biological Tissues." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc849725/.

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Laser Ablation Inductively coupled plasma mass spectrometry (LA-ICP-MS) and Raman spectroscopy are both powerful imaging techniques. Their applications are numerous and extremely potential in the field of biology. In order to improve upon LA-ICP-MS an in-house built cold cell was developed and its effectiveness studied by imaging Brassica napus seeds. To further apply LA-ICP-MS and Raman imaging to the field of entomology a prong gilled mayfly (Ephemeroptera: Leptophlebiidae) from the Róbalo River, located on Navarino Island in Chile, was studied. Analysis of both samples showcased LA-ICP-MS and Raman spectroscopy as effective instruments for imaging trace elements and larger molecules in biological samples respectively.
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Managh, Amy J. "Single-cell tracking of therapeutic cells using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry." Thesis, Loughborough University, 2014. https://dspace.lboro.ac.uk/2134/16723.

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Cellular therapy is emerging as a clinically viable strategy in the field of solid organ transplantation, where it is expected to reduce the dependency on conventional immunosuppression. This has produced a demand for highly sensitive methods to monitor the persistence and tissue distribution of administered cells in vivo. However, tracking cells presents significant challenges. In many cases transplanted cells are autologous with the immune system of the transplant recipient, and hence are invisible to typical methods of detection. To enable their differentiation, the cells must be labelled with a suitable, non-toxic and long lifetime label, prior to their administration to patients. In addition, administered cells represent only a small fraction of the recipient's endogenous cells, which necessitates the use of an extremely sensitive detection method. Laser ablation – inductively coupled plasma – mass spectrometry (LA-ICP-MS) is an exquisitely sensitive analytical technique, capable of imaging trace elements in complex samples, at high spatial resolution.
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Naes, Benjamin E. "Elemental Analysis of Glass and Ink by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) and Laser Induced Breakdown Spectroscopy (LIBS)." FIU Digital Commons, 2009. http://digitalcommons.fiu.edu/etd/207.

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The necessity of elemental analysis techniques to solve forensic problems continues to expand as the samples collected from crime scenes grow in complexity. Laser ablation ICP-MS (LA-ICP-MS) has been shown to provide a high degree of discrimination between samples that originate from different sources. In the first part of this research, two laser ablation ICP-MS systems were compared, one using a nanosecond laser and another a femtosecond laser source for the forensic analysis of glass. The results showed that femtosecond LA-ICP-MS did not provide significant improvements in terms of accuracy, precision and discrimination, however femtosecond LA-ICP-MS did provide lower detection limits. In addition, it was determined that even for femtosecond LA-ICP-MS an internal standard should be utilized to obtain accurate analytical results for glass analyses. In the second part, a method using laser induced breakdown spectroscopy (LIBS) for the forensic analysis of glass was shown to provide excellent discrimination for a glass set consisting of 41 automotive fragments. The discrimination power was compared to two of the leading elemental analysis techniques, µXRF and LA-ICP-MS, and the results were similar; all methods generated >99% discrimination and the pairs found indistinguishable were similar. An extensive data analysis approach for LIBS glass analyses was developed to minimize Type I and II errors en route to a recommendation of 10 ratios to be used for glass comparisons. Finally, a LA-ICP-MS method for the qualitative analysis and discrimination of gel ink sources was developed and tested for a set of ink samples. In the first discrimination study, qualitative analysis was used to obtain 95.6% discrimination for a blind study consisting of 45 black gel ink samples provided by the United States Secret Service. A 0.4% false exclusion (Type I) error rate and a 3.9% false inclusion (Type II) error rate was obtained for this discrimination study. In the second discrimination study, 99% discrimination power was achieved for a black gel ink pen set consisting of 24 self collected samples. The two pairs found to be indistinguishable came from the same source of origin (the same manufacturer and type of pen purchased in different locations). It was also found that gel ink from the same pen, regardless of the age, was indistinguishable as were gel ink pens (four pens) originating from the same pack.
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Bartle, Emma Kathleen. "Provenance establishment and authentication of South-East Asian ceramics using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS)." University of Western Australia. Centre for Forensic Science, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0104.

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[Truncated abstract] The sale of fraudulent South-East Asian ceramics constitutes a large proportion of the illegal artefact and antique trade and threatens to undermine the legitimate international market. The sophistication and skill of forgers has reached a level where, using traditional appraisal by eye and hand, even the most experienced specialist is often unable to distinguish between a genuine and fraudulent piece. In addition, the current scientific method of authentication used by the international antiques and art industry, thermoluminescence (TL) dating, carries severe limitations. The technique has an error margin of +/-20 % and requires the removal of a significant piece of the sample being tested, which decreases both the monetary and cultural value of the artefact. Of more concern, forgers have developed methods which produce false test results and which appear to corroborate false claims for the age of artefacts. Consequently, the use of TL dating for authentication of ancient ceramics, especially those of South-East Asian origin, has now come into serious question. The most suitable method for authenticating ceramics is through provenance establishment. Studies published in the literature have investigated the application of various analytical techniques to provide this information for ceramic wares and have highlighted their potential to be used for provenance establishment. However, the value of each of these techniques is limited rendering them generally unsuitable for practical use in the international antiques and art world to authenticate high-value South-East Asian artefacts. Consequently, there is a desperate need for the development of a robust, accurate and non-destructive method which can be practically applied in the industry to authenticate South-East Asian ceramics. ... Minor variations between spectral profiles of artefacts produced in the same country have also been used to further provenance artefacts to a specific production region or kiln site. The results of analyses have been compiled to form a unique reference database which can be added to in the future and used by experts internationally. Adaptation of the developed sampling and analytical methodologies to allow in-situ sampling of large artefacts using the
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Jantzi, Sarah C. "Elemental Analysis and Forensic Comparison of Soils by Laser-Induced Breakdown Spectroscopy (LIBS) and Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS)." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/967.

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The elemental analysis of soil is useful in forensic and environmental sciences. Methods were developed and optimized for two laser-based multi-element analysis techniques: laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and laser-induced breakdown spectroscopy (LIBS). This work represents the first use of a 266 nm laser for forensic soil analysis by LIBS. Sample preparation methods were developed and optimized for a variety of sample types, including pellets for large bulk soil specimens (470 mg) and sediment-laden filters (47 mg), and tape-mounting for small transfer evidence specimens (10 mg). Analytical performance for sediment filter pellets and tape-mounted soils was similar to that achieved with bulk pellets. An inter-laboratory comparison exercise was designed to evaluate the performance of the LA-ICP-MS and LIBS methods, as well as for micro X-ray fluorescence (μXRF), across multiple laboratories. Limits of detection (LODs) were 0.01-23 ppm for LA-ICP-MS, 0.25-574 ppm for LIBS, 16-4400 ppm for µXRF, and well below the levels normally seen in soils. Good intra-laboratory precision (≤ 6 % relative standard deviation (RSD) for LA-ICP-MS; ≤ 8 % for µXRF; ≤ 17 % for LIBS) and inter-laboratory precision (≤ 19 % for LA-ICP-MS; ≤ 25 % for µXRF) were achieved for most elements, which is encouraging for a first inter-laboratory exercise. While LIBS generally has higher LODs and RSDs than LA-ICP-MS, both were capable of generating good quality multi-element data sufficient for discrimination purposes. Multivariate methods using principal components analysis (PCA) and linear discriminant analysis (LDA) were developed for discriminations of soils from different sources. Specimens from different sites that were indistinguishable by color alone were discriminated by elemental analysis. Correct classification rates of 94.5 % or better were achieved in a simulated forensic discrimination of three similar sites for both LIBS and LA-ICP-MS. Results for tape-mounted specimens were nearly identical to those achieved with pellets. Methods were tested on soils from USA, Canada and Tanzania. Within-site heterogeneity was site-specific. Elemental differences were greatest for specimens separated by large distances, even within the same lithology. Elemental profiles can be used to discriminate soils from different locations and narrow down locations even when mineralogy is similar.
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Reid, Joy Emily. "The development and geological application of a whole rock-LA-ICP-MS technique for the determination of high field strength elements." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0004/MQ42434.pdf.

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Veinott, G. "Elemental concentrations in the fin rays of white sturgeon, Acipenser transmontanus, by laser ablation sampling-inductively coupled plasma-mass spectrometry (LAS-ICP-MS)." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq40492.pdf.

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Books on the topic "Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)"

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1970-, Speakman Robert J., and Neff Hector, eds. Laser ablation ICP-MS in archaeological research. Albuquerque, [N.M.]: University of New Mexico Press, 2005.

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Hubbard, Dale A. A paleogeochemical investigation of ferromanganese oxyhydroxides from the Mendocino Ridge using laser ablation inductively-coupled plasma mass spectrometry (LA ICP-MS). 1999.

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Book chapters on the topic "Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)"

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Vogt, Carla, and Christopher Latkoczy. "Laser Ablation ICP-MS." In Inductively Coupled Plasma Mass Spectrometry Handbook, 228–58. Oxford, UK: Blackwell Publishing Ltd., 2009. http://dx.doi.org/10.1002/9781444305463.ch6.

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Becker, Sabine, and Susanne Becker. "Bioimaging of Metals and Proteomic Studies of Clinical Samples by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS)." In Analytical Techniques for Clinical Chemistry, 479–505. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118271858.ch17.

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Sonet, Jordan, Sandra Mounicou, and Laurent Chavatte. "Detection of Selenoproteins by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP MS) in Immobilized pH Gradient (IPG) Strips." In Methods in Molecular Biology, 205–17. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7258-6_15.

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Becker, J. Sabine, and J. Susanne Becker. "Imaging of Metals, Metalloids, and Non-metals by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) in Biological Tissues." In Methods in Molecular Biology, 51–82. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-746-4_3.

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Cruz, Elisa Castañeda Santa, J. Susanne Becker, J. Sabine Becker, and Alessandra Sussulini. "Imaging of Selenium by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) in 2-D Electrophoresis Gels and Biological Tissues." In Methods in Molecular Biology, 219–27. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7258-6_16.

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Walder, Heather. "Laser Ablation–Inductively Coupled Plasma–Mass Spectrometry (LA-ICP-MS) Analysis of Refired Glass Pendants from the North American Upper Great Lakes." In ACS Symposium Series, 365–95. Washington, DC: American Chemical Society, 2013. http://dx.doi.org/10.1021/bk-2013-1147.ch020.

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S. Amais, Renata, Danielle S. Francischini, Pedro S. Moreau, and Marco A.Z. Arruda. "Laser Chemical Elemental Analysis: From Total to Images." In Practical Applications of Laser Ablation. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.94385.

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This book chapter focuses on laser ablation employed in elemental analysis and discusses the fundamentals and instrumentation of the laser-induced breakdown spectroscopy (LIBS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) techniques. The analytical performance of such techniques, challenges related to calibration, and strategies to improve sensitivity are discussed. In addition, the processes involved in data acquisition and imaging for acquiring the elemental spatial distribution are highlighted, and some representative examples in environmental, biological, medical, and forensic researches are presented.
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"Appendix B: Laser Ablation-Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS)." In Thermal Ionization Mass Spectrometry (TIMS), 315–18. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527696413.app2.

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Huang, Boling, Xuan Wang, Tingting Yang, Jiani Shen, Qingzheng Ma, Yong Zhu, Lansen Li, and Xihan Yang. "Uncertainty Evaluation for Determination of Gold in High-Purity Gold by LA-ICP-MS." In Advances in Transdisciplinary Engineering. IOS Press, 2021. http://dx.doi.org/10.3233/atde210308.

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Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a new analytical method developed in recent years. The LA-ICP-MS is a quasi-non-destructive multi-elemental analytical method with low detection limits, high sensitivity and specificity. In this study, this method is applied to detecting high-purity gold. The micro-region information of high-purity gold can be analysed, and the original position information of the sample can be obtained in real time and accurately. In this study, the content of impurity elements in high-purity gold were determined by LA-ICP-MS, and the accuracy and reliability of the test results were improved by calculating the uncertainty. According to the test and analysis, the gold content of the high purity gold sample is (999.995 ± 0.003) ‰, so the gold content of the sample is more than 999.99 ‰. The result shows that the LA-ICP-MS has the advantages of fast, accurate and green, which is conducive to the rapid development of jewellery industry technology, and puts forward guiding suggestions for the production development direction, and promotes the green and healthy development of jewellery industry.
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Ghazi, A. Mohamad. "APPLICATIONS OF LASER ABLATION INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (LA-ICP-MS) IN ENVIRONMENTAL FORENSIC STUDIES." In Introduction to Environmental Forensics, 637–69. Elsevier, 2007. http://dx.doi.org/10.1016/b978-012369522-2/50015-4.

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Conference papers on the topic "Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)"

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Marzi, Anne, Ilona Nordhorn, Kai Eder, Antje Vennemann, Martin Wiemann, Uwe Karst, Björn Kemper, and Jürgen Schnekenburger. "Digital holographic microscopy complements mass spectrometry for label-free quantification of nanoparticles within single cells." In Digital Holography and Three-Dimensional Imaging. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/dh.2022.m4a.6.

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We combined laser ablation inductively coupled plasma-mass spectrometry (LA-ICP-MS) with volume measurement by digital holographic microscopy (DHM) to determine the concentration of CeO2 nanoparticles in single lung epithelial cells.
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Weiskirchen, R., P. Kim, S. Weiskirchen, R. Uerlings, A. Kueppers, F. Stellmacher, A. Viveiros, and H. Zoller. "Quantification of hepatic liver iron overload with laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)." In 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0038-1677110.

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Muñoz, Juan José Augusto Moyano, Sandra A. Drigo, Fabio Marchi, Gustavo Pessoa, Cristovam S. Neto, Gustavo Guimaraes, Marco A. Z. Arruda, and Silvia R. Rogatto. "Abstract 4303: Bioimaging of multiple elements by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) in penile carcinomas." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4303.

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Binder, Fritz, and Stefan L. Burtscher. "Improvements in chloride determination in reinforced concrete structures to find optimal time for remediation." In IABSE Symposium, Prague 2022: Challenges for Existing and Oncoming Structures. Zurich, Switzerland: International Association for Bridge and Structural Engineering (IABSE), 2022. http://dx.doi.org/10.2749/prague.2022.1942.

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<p>For a highway operator, such as ASFiNAG, bridges are very important assets. Despite all regular maintenance measures, these structures are strongly subjected to ageing and degradation, because of their exposure. Thus, leading to high maintenance expenditures. In Austria strong winters are obligatory and, therefore, de-icing measures are used for thawing. These substances contain chlorides, which are dissolved in water. Several elements of the bridges – especially the columns – are severely exposed. The exposure over many years leads to serious concrete degradation, depassivation of the rebars and pitting corrosion.</p><p>The LA-ICP-MS (Laser Ablation Inductively Coupled Plasma Mass Spectrometry) method presented in this paper is a fast and reliable analysis strategy for determination of the chloride content in the cement phase of existing concrete structures. The high accuracy and depth resolution of the chloride profiles enable a more precise data assessment for forecast models.</p><p>For this purpose, chloride profiles were taken from a retaining wall at different heights. The analysis shows significant deviations comparing traditional and new method concerning chloride contend. The challenges associated with such deviations in relation with the optimal time for remediation are shown in an example investigation.</p>
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Binder, Fritz, Stefan L. Burtscher, and Alfred Strauss. "Prediction of chloride profiles and discussion of time variant alterations." In IABSE Symposium, Guimarães 2019: Towards a Resilient Built Environment Risk and Asset Management. Zurich, Switzerland: International Association for Bridge and Structural Engineering (IABSE), 2019. http://dx.doi.org/10.2749/guimaraes.2019.1250.

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<p>For a highway operator, such as ASFiNAG, bridges are very important assets. Despite all regular maintenance measures, these structures are strongly subjected to ageing and degradation, because of their exposure. Thus, leading to high maintenance expenditures. In Austria strong winters are obligatory and, therefore, de-icing measures are used for thawing. These substances contain chlorides, which are dissolved in water. Several elements of the bridges – especially the columns – are severely exposed. The exposure over many years leads to serious concrete degradation, depassivation of the rebars and pitting corrosion.</p><p>The LA-ICP-MS (Laser Ablation Inductively Coupled Plasma Mass Spectrometry) method presented in this paper is a fast and reliable analysis strategy and a novel technique in terms determination the chloride content in the cement phase of existing concrete structures. The high accuracy and depth resolution of the chloride profiles enable a more precise data assessment for forecast models. For this purpose, chloride profiles were taken from a retaining wall at different heights in weekly intervals in the year 2016/2017 and in October of 2012. In conjunction with moisture monitoring and additional environmental data, as well as data from the de-icing salt deposit, it reveals important interrelations and dependencies to the measured profiles. This data enables new insight in the prediction of the development of the chloride profiles over time and depth. To apply the findings into practice, two analytical models were used to show the complexity and sensitivity of the derived input parameters.</p>
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Ellison, Sonia M., Yvette D. Kuiper, Jim L. Crowley, and Daniel P. Murray. "U-PB LASER ABLATION INDUCTIVELY COUPLED MASS SPECTROMETRY (U-PB LA-ICP-MS) ZIRCON AGE CONSTRAINTS ON THE TECTONIC ORIGIN OF THE AVALON TERRANE IN SOUTHEASTERN NEW ENGLAND." In GSA Annual Meeting in Phoenix, Arizona, USA - 2019. Geological Society of America, 2019. http://dx.doi.org/10.1130/abs/2019am-338684.

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Pan, Zixiao, Wei Wei, and Fuhe Li. "Fast Turn-around Failure Analysis of Metal Interconnection Using FIB and LA ICP-MS." In ISTFA 2010. ASM International, 2010. http://dx.doi.org/10.31399/asm.cp.istfa2010p0285.

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Abstract This paper introduces our effort in failure analysis of a 200 nm thick metal interconnection on a glass substrate and covered with a passivation layer. Structural damage in localized areas of the metal interconnections was observed with the aid of focused ion beam (FIB) cross-sectioning. Laser ablation inductively coupled plasma mass spectroscopy (LA ICP-MS) was then applied to the problematic areas on the interconnection for chemical survey. LA ICP-MS showed direct evidence of localized chemical contamination, which has likely led to corrosion (or over-etching) of the metal interconnection and the assembly failure. Due to the high detection sensitivity of LA ICP-MS and its compatibility with insulating material analysis, minimal sample preparation is required. As a result, the combination of FIB and LA ICP-MS enabled successful meso-scale failure analysis with fast turnaround and reasonable cost.
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de Villiers, Johan P. R., Noko Ngoepe, James Roberts, and Alison S. Tuling. "Evaluation of the Phase Composition, Crystallinity and Trace Isotope Variation of SiC in Experimental TRISO Coated Particles." In Fourth International Topical Meeting on High Temperature Reactor Technology. ASMEDC, 2008. http://dx.doi.org/10.1115/htr2008-58208.

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The silicon carbide layers in experimental TRISO coated particles with zirconia kernels were evaluated for their phase composition, their impurity levels and the crystal perfection and twinning of the crystallites in the layers. This evaluation was necessary to compare the different SiC layers and to relate these properties to various quality tests and ultimately to manufacturing parameters in the CVD coater. Identification of the various polytypes was done using electron diffraction methods. This is the only method for the unequivocal identification of the different polytypes. The 3C, and 6H polytypes were positively identified. A feature of the SiC in some samples is the disordered nature of the phase. The disorder is characterised by planar defects, of different width and periodicity, giving rise to streaking in the diffraction pattern along the [111] direction of the 3C polytype. Polarised light microscopy in transmission is a useful tool to easily distinguish between the cubic (beta) and non-cubic (alpha) SiC in the layers. It also provides valuable information about the distribution of these phases in the layers. Raman spectroscopy was used to examine the distribution of Si in the SiC layers of the different samples. Two samples contain elevated levels of Si, of the order of 50%, with the highest levels on the inside of the layers. The elevated Si levels also occur in most of the other samples, albeit at lower Si levels. This was also confirmed by use of SEM electron backscatter analysis. Rietveld analysis using X-ray diffraction is presently the only reliable method to quantify the polytypes in the SiC layer. It was found that the SiC layer consists predominantly (82% to 94%) of the 3C polytype, with minor amounts of the 6H and 8H polytypes. Impurities in the SiC and PyC could be measured with sufficient sensitivity using laser ablation inductively coupled mass spectrometry (LA-ICP-MS). The SiC and PyC layers are easily located from the intensity of the C13 and Si29 signals. In most cases the absolute values are of less concern than the variation of impurities in the samples. Elevated levels of the transition elements Cu, Ni, Co, Cr and Zn are present erratically in some samples. These elements, together with Ag107 and Ag109, correlate positively, indicating impurities, even metallic particles. Elevated levels of these transition elements are also present at the SiC/OPyC (Outer Pyrolytic Carbon) interface. The reasons for this are unknown at this stage. NIST standards were used to calibrate the impurity levels in the coated particles. These average from 1 to 18 ppm for some isotopes.
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Reports on the topic "Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)"

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Leybourne, M. I., J. M. Peter, M A Schmidt, D. Layton-Matthews, A. Voinot, and L. Mathieu. Geochemical evidence for a magmatic contribution to the metal budget of the Windy Craggy Cu-Co(±Zn) volcanogenic massive-sulfide deposit, northwestern British Columbia. Natural Resources Canada/CMSS/Information Management, 2022. http://dx.doi.org/10.4095/328018.

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Volcanogenic massive-sulfide (VMS) deposits may have had metal contributions from magmatic degassing and leaching of footwall rocks. The Windy Craggy Cu-Co-Zn VMS deposit in northwestern British Columbia may include magmatic contributions, based on laser-ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) of fluid inclusions (enriched in Sb, Sn, and Bi) and lithogeochemistry. Sulfide-mineral trace-element abundances in the massive-sulfide orebody, underlying stockwork zone, gold zone, and altered and unaltered mafic rock and argillite were analyzed by LA-ICP-MS. Elevated Au, W, As, Bi, Sb, Se, Te, Tl, Ag, Co, and Mo contents occur within the gold and/or stockwork zones. Increasing 'magmatic metals' with increasing Co/Ni values suggest direct magmatic contribution to the deposit. Covariation of Co with these so-called 'magmatic elements' indicates that it, too, may be of magmatic origin, sourced via fluids exsolved from a crystallizing magma; however, evidence from the composition of rocks and sulfide minerals from Windy Craggy and other VMS deposits suggests that there is probably no meaningful distinction between hydrothermal leaching and direct magmatic contributions and that most - if not all - fluids that form VMS deposits should be termed 'magmatic-hydrothermal'.
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