Relevant bibliographies by topics / Laryngopharyngeal sensitivity

Academic literature on the topic 'Laryngopharyngeal sensitivity'

Author: Grafiati
Published: 4 June 2021
Last updated: 21 February 2023

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Journal articles on the topic "Laryngopharyngeal sensitivity"

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Masaany, M., M. B. Marina, W. P. Sharifa Ezat, and A. Sani. "Empirical treatment with pantoprazole as a diagnostic tool for symptomatic adult laryngopharyngeal reflux." Journal of Laryngology & Otology 125, no. 5 (February 28, 2011): 502–8. http://dx.doi.org/10.1017/s0022215111000120.

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AbstractObjective:To determine the sensitivity and specificity of intensive empirical treatment with pantoprazole in diagnosing laryngopharyngeal reflux in adults.Study design:This was a prospective, double-blind study.Subjects and methods:Fifty-five patients with either a Reflux Symptom Index of more than 13 or a Reflux Finding Score of more than 7 were enrolled. All patients underwent 24-hour, double-probe pH monitoring before commencing pantoprazole 40 mg twice daily; both investigators and patients were blinded to pH monitoring results. The Reflux Symptom Index and Reflux Finding Score were reassessed during the second, third and fourth month of follow up.Results:The sensitivity of empirical pantoprazole treatment in diagnosing laryngopharyngeal reflux was 92.5 per cent. The specificity was 14.2 per cent, the positive predictive value 86 per cent and the negative predictive value 25 per cent. There was significant reduction in the total Reflux Symptom Index and Reflux Finding Score after the second, third and fourth month of treatment. There was no correlation between laryngopharyngeal reflux and body mass index.Conclusion:Our results suggest that intensive empirical treatment with proton pump inhibitors is effective in diagnosing laryngopharyngeal reflux.
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Ni, X.-G., Q.-Q. Zhang, and G.-Q. Wang. "Narrow band imaging versus autofluorescence imaging for head and neck squamous cell carcinoma detection: a prospective study." Journal of Laryngology & Otology 130, no. 11 (October 6, 2016): 1001–6. http://dx.doi.org/10.1017/s0022215116009002.

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AbstractObjectives:This study aimed to compare the diagnostic effectiveness of narrow band imaging and autofluorescence imaging for malignant laryngopharyngeal tumours.Methods:Between May 2010 and October 2010, 50 consecutive patients with suspected laryngopharyngeal tumour underwent endoscopic laryngopharynx examination. The morphological characteristics of laryngopharyngeal lesions were analysed using high performance endoscopic systems equipped with narrow band imaging and autofluorescence imaging modes. The diagnostic effectiveness of white light image, narrow band imaging and autofluorescence imaging endoscopy for benign and malignant laryngopharyngeal lesions was evaluated.Results:Under narrow band imaging endoscopy, the superficial microvessels of squamous cell carcinomas appeared as dark brown spots or twisted cords. Under autofluorescence imaging endoscopy, malignant lesions appeared as bright purple. The sensitivity of malignant lesion diagnosis was not significantly different between narrow band imaging and autofluorescence imaging modes, but was better than for white light image endoscopy (χ2 = 12.676, p = 0.002). The diagnostic specificity was significantly better in narrow band imaging mode than in both autofluorescence imaging and white light imaging mode (χ2 = 8.333, p = 0.016).Conclusion:Narrow band imaging endoscopy is the best option for the diagnosis and differential diagnosis of laryngopharyngeal tumours.
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Zelchan, Roman, Vladimir Chernov, Anna Titskaya, Ivan Sinilkin, Svetlana Chizhevskaya, and Yevgeniy Ts Choynzonov. "Diagnostic Efficiency of Single-Photon Emission Computed Tomography with 99MTc-MIBI in Visualization of Malignant Tumors of the Larynx and Laryngopharynx." Advanced Materials Research 1084 (January 2015): 373–76. http://dx.doi.org/10.4028/www.scientific.net/amr.1084.373.

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To study the diagnostic efficiency of single-photon emission computed tomography (SPECT) with 99mTc-MIBI 40 patients were chosen for diagnosing primary and recurrence of laryngeal or laryngopharyngeal cancer and as well as patients with benign diseases of the larynx. All patients underwent SPECT with 99mTc-MIBI. As a result it has been found that the sensitivity, specificity and accuracy of SPECT with 99mTc-MIBI in the diagnostics of primary tumors of the larynx are 95%, 80% and 92%, respectively. The visualization of recurrent tumors of the larynx and laryngopharynx has showed 100% sensitivity. The obtained results have proved the consistency of SPECT with 99mTc-MIBI as an additional method of diagnostics of <em>laryngeal and laryngopharyngeal</em> cancer.
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Clayton, Nicola A., Giselle D. Carnaby-Mann, Matthew J. Peters, and Alvin J. Ing. "The Effect of Chronic Obstructive Pulmonary Disease on Laryngopharyngeal Sensitivity." Ear, Nose & Throat Journal 91, no. 9 (September 2012): 370–82. http://dx.doi.org/10.1177/014556131209100907.

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Powell, Jason, and Helen C. Cocks. "Mucosal changes in laryngopharyngeal reflux-prevalence, sensitivity, specificity and assessment." Laryngoscope 123, no. 4 (December 3, 2012): 985–91. http://dx.doi.org/10.1002/lary.23693.

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Zeleník, Karol, Viktória Hránková, Adéla Vrtková, Lucia Staníková, Pavel Komínek, and Martin Formánek. "Diagnostic Value of the PeptestTM in Detecting Laryngopharyngeal Reflux." Journal of Clinical Medicine 10, no. 13 (July 5, 2021): 2996. http://dx.doi.org/10.3390/jcm10132996.

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Background: The PeptestTM is a non-invasive diagnostic test for measuring the pepsin concentration in saliva, which is thought to correlate with laryngopharyngeal reflux (LPR). The aim of this study was to investigate the diagnostic value of the Peptest in detecting LPR based on 24-h multichannel intraluminal impedance-pH (MII-pH) monitoring using several hypopharyngeal reflux episodes as criterion for LPR. Methods: Patients with suspected LPR were examined with the Reflux Symptom Index (RSI), Reflux Finding Score (RFS), fasting Peptest, and MII-pH monitoring. We calculated the accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the Peptest, RSI, and RFS based on the threshold of one and six hypopharyngeal reflux episodes. Results: Altogether, the data from 46 patients were analyzed. When one hypopharyngeal reflux episode was used as a diagnostic threshold for LPR, the accuracy, sensitivity, specificity, PPV, and NPV were, respectively, as follows: 35%, 33%, 100%, 100%, and 3%, for the Peptest; 39%, 40%, 0%, 95%, and 0%, for the RSI; and 57%, 58%, 0%, 96%, and 0%, for the RFS. The accuracy, sensitivity, specificity, PPV, and NPV of the Peptest for diagnosing gastroesophageal reflux disease (GERD) were 46%, 27%, 63%, 40.0%, and 48%, respectively. Conclusions: A positive Peptest is highly supportive of a pathological LPR diagnosis. However, a negative test could not exclude LPR.
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Son, Joseph, Jana Havranova, and Aaron Jaworek. "3095 Non-Celiac Gluten Sensitivity (NCGS) Presenting as Laryngopharyngeal Reflux (LPR)." American Journal of Gastroenterology 114, no. 1 (October 2019): S1663—S1664. http://dx.doi.org/10.14309/01.ajg.0000601912.80809.d4.

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Clayton, Nicola A., Giselle D. Carnaby, Matthew J. Peters, and Alvin J. Ing. "Impaired laryngopharyngeal sensitivity in patients with COPD: The association with swallow function." International Journal of Speech-Language Pathology 16, no. 6 (February 24, 2014): 615–23. http://dx.doi.org/10.3109/17549507.2014.882987.

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9

Zhou, Yu, Ruixia Ma, Jiangbo Luo, Zhikai Wang, and Pei Yang. "Role of Laryngopharyngeal Reflux Changes in Children with Adenoid Hypertrophy: A Randomized Controlled Prospective Study." Evidence-Based Complementary and Alternative Medicine 2023 (February 6, 2023): 1–6. http://dx.doi.org/10.1155/2023/5628551.

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Objectives. This prospective randomized controlled analysis aimed to assess the changes in laryngopharyngeal reflux (LPR) in children with adenoid hypertrophy (AH). Study design: a prospective, randomized, and controlled analysis. Methods. The reflux symptom index (RSI) and the reflux finding score (RFS) scores were used to evaluate the laryngopharyngeal reflux changes in children diagnosed with adenoid hypertrophy. The pepsin concentration in salivary samples was examined, and the positive pepsin was used to assess the sensitivity and specificity of RSI, RFS, and RSI combined with RFS in forecasting LPR. Results. In 43 children with AH, the sensitivity of the RSI and RFS scale (used alone or in combination) in diagnosing pharyngeal reflux in children with adenoid hypertrophy was lower. Pepsin expression was identified in 43 items of salivary samples, with a total positive rate of 69.77%, most of which were optimistic. The expression level of pepsin was positively correlated with the grade of adenoid hypertrophy (r = 0.576, P < 0.01 ). Based on the positive rate of pepsin, we found that the sensitivity and specificity of RSI and RFS were 5.77%, 35.03%, and 91.74%, 55.89%. Moreover, there was a noticeable distinction in the number of acid reflux episodes between the LPR-positive and LPR-negative groups. Conclusion. There is a special connection between LPR change and children’s AH. LPR exerts a crucial role in the progression of children’s AH. Because of the low sensitivity of RSI and RFS, it is not suitable for LPR children to choose AH.
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Belafsky, Peter C., Gregory N. Postma, and James A. Koufman. "The Association between Laryngeal Pseudosulcus and Laryngopharyngeal Reflux." Otolaryngology–Head and Neck Surgery 126, no. 6 (June 2002): 649–52. http://dx.doi.org/10.1067/mhn.2002.125603.

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BACKGROUND: A pattern of edema on the ventral surface of the vocal fold, called pseudosulcus vocalis, was described in 1995. It refers to infraglottic edema extending from the anterior commissure to the posterior larynx. It can be differentiated from sulcus vergeture, which is caused by adhesion of the vocal fold epithelium to the vocal ligament. Although it has been related to laryngopharyngeal reflux (LPR), this has not been thoroughly investigated. PURPOSE: Our goal was to evaluate the association between pseudosulcus and LPR. METHODS: Thirty patients with a clinical diagnosis of LPR confirmed by double-probe pH monitoring and 30 controls without LPR were enrolled. The prevalence of pseudosulcus was determined with fiberoptic laryngoscopy. RESULTS: Seventy percent (21 of 30) of patients with LPR and 30% (9 of 30) of controls had pseudosulcus. Patients with pseudosulcus were 2.3 times more likely to have pH-documented LPR (95% confidence interval 1.3–4.2). The sensitivity and specificity of pseudosulcus in the diagnosis of LPR are 70% and 77%, respectively. CONCLUSIONS: Pseudosulcus is highly correlated with pH-documented LPR ( P < 0.001). The presence of pseudosulcus is suggestive of LPR.
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Dissertations / Theses on the topic "Laryngopharyngeal sensitivity"

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Clayton, Nicola. "The effect of COPD on laryngopharyngeal sensitivity and swallow function." Connect to full text, 2007. http://hdl.handle.net/2123/2236.

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Thesis (M. Sc. Med.)--University of Sydney, 2008.
Title from title screen (viewed 29 July 2008). Submitted in fulfilment of the requirements for the degree of Master of Science in Medicine to the Discipline of Medicine, Faculty of Medicine. Degree awarded 2008; thesis submitted 2007. Includes bibliographical references. Also available in print form.
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Clayton, Nicola Ann. "The Effect of Chronic Obstructive Pulmonary Disease on Laryngopharyngeal Sensitivity and Swallow Function." Thesis, The University of Sydney, 2007. http://hdl.handle.net/2123/2236.

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The relationship between COPD and laryngopharyngeal sensitivity has not been previously determined. Limited research into the relationship between COPD and swallow function suggests that patients with COPD are at increased risk of aspiration. One possible mechanism for this is a reduction in laryngopharyngeal sensitivity (LPS). Reduced laryngopharyngeal sensitivity (LPS) has been associated with an increased risk of aspiration in pathologies such as stroke, however impaired LPS has not been examined with respect to aspiration risk in COPD. The Aims of this study were to investigate the effect of COPD on laryngopharyngeal sensation using Laryngopharyngeal Sensory Discrimination Testing (LPSDT) and to determine whether a relationship between LPS and swallow function in patients with proven COPD exists. Method: 20 patients with proven COPD and 11 control subjects underwent LPSDT utilising an air-pulse stimulator (Pentax AP4000) via a nasendoscope (Pentax FNL10AP). The threshold of laryngopharyngeal sensation was measured by the air pressure required to elicit the laryngeal adductor reflex (LAR). A number of further examinations were also completed for COPD subjects. These included respiratory function testing, self-reporting questionnaire on swallowing ability (SSQ), bedside clinical examination of swallowing (MASA) and endoscopic assessment of swallowing (EAS). Results: subjects with COPD had a significantly higher LAR threshold when compared to their normal healthy counterparts (p<0.001). Positive correlations were identified for the relationships between MASA score and EAS results for presence of laryngeal penetration / aspiration (p<0.04), vallecular residue (p<0.01) and piriform residue (p<0.01). Conclusion: Patients with COPD have significantly reduced mechanosensitivity in the laryngopharynx. Patients with COPD also have impaired swallow function characterised primarily by pharyngeal stasis. These changes may place patients with COPD at increased risk of aspiration.
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Clayton, Nicola Ann. "The Effect of Chronic Obstructive Pulmonary Disease on Laryngopharyngeal Sensitivity and Swallow Function." University of Sydney. Faculty of Medicine, 2007. http://hdl.handle.net/2123/2236.

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Masters of Science in Medicine
The relationship between COPD and laryngopharyngeal sensitivity has not been previously determined. Limited research into the relationship between COPD and swallow function suggests that patients with COPD are at increased risk of aspiration. One possible mechanism for this is a reduction in laryngopharyngeal sensitivity (LPS). Reduced laryngopharyngeal sensitivity (LPS) has been associated with an increased risk of aspiration in pathologies such as stroke, however impaired LPS has not been examined with respect to aspiration risk in COPD. The Aims of this study were to investigate the effect of COPD on laryngopharyngeal sensation using Laryngopharyngeal Sensory Discrimination Testing (LPSDT) and to determine whether a relationship between LPS and swallow function in patients with proven COPD exists. Method: 20 patients with proven COPD and 11 control subjects underwent LPSDT utilising an air-pulse stimulator (Pentax AP4000) via a nasendoscope (Pentax FNL10AP). The threshold of laryngopharyngeal sensation was measured by the air pressure required to elicit the laryngeal adductor reflex (LAR). A number of further examinations were also completed for COPD subjects. These included respiratory function testing, self-reporting questionnaire on swallowing ability (SSQ), bedside clinical examination of swallowing (MASA) and endoscopic assessment of swallowing (EAS). Results: subjects with COPD had a significantly higher LAR threshold when compared to their normal healthy counterparts (p<0.001). Positive correlations were identified for the relationships between MASA score and EAS results for presence of laryngeal penetration / aspiration (p<0.04), vallecular residue (p<0.01) and piriform residue (p<0.01). Conclusion: Patients with COPD have significantly reduced mechanosensitivity in the laryngopharynx. Patients with COPD also have impaired swallow function characterised primarily by pharyngeal stasis. These changes may place patients with COPD at increased risk of aspiration.
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