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1

Peter G. J. M. Janssen. Lactate threshold training. Champaign, IL: Human Kinetics, 2001.

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2

Janssen, Peter. Training lactate pulse rate. Oulu, Finland: Polar Electro Oy, 1989.

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3

The blood lactate response to exercise. Champaign, IL: Human Kinetics, 1995.

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4

Beaudoin, Marc. Glucose, lactate and lactate dehydrogenase levels in the human kidney carcinoma cell line A498 (ATCC HTB-44). Sudbury, Ont: Laurentian University, 1993.

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5

Boyce, Julian. Lactate dehydrogenase isoenzymes in malignant serous effusions. [s.l: The Author], 1989.

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6

Ogliaruso, Michael A. Synthesis of lactones and lactams. Chichester: Wiley, 1993.

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7

Lee, R. J. Lactic acid metabolism and lactate dehydrogenases of Vibrio species. Portsmouth: Portsmouth Polytechnic,School of Pharmacy..., 1987.

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8

Muldoon, Lori. Glucose, lactate, and lactate dehydrogenase activity of the small cell lung cancer line H-209 and the drug resistant variant H-209/V6. Sudbury, Ont: Laurentian University, 1992.

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9

Roberts, Philip Anthony. Differences in blood lactate concentrations as a measure of fitness between institute and club swimmers following a period of training: BA(Hons) Human Movement Studies dissertation. Cardiff: SGIHE, 1987.

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10

Urajnik, Diana J. The effects of lactate oxidase on human MCF7 breast cancer cells. Sudbury, Ont: Laurentian University, 1998.

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11

Kim, Tae-gwŏn. Sangji mit haji undong hu hoebok chokŏn i sinchʻe tallyŏn puwi ŭi yusan chegŏyul kwa subsequent performance e michʻinŭn hyokwa: Effects of recovery condition on blood lactate removal rate and subsequent performance of trained limbs after arm and leg exercise. Korea: s. n., 1986.

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12

Mulholland, Peter. M-subunit lactate dehydrogenase in aspirated fluids from benign and malignant lesions. [s.l: The Author], 1988.

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13

Woods, Trevor Alfred John. The effects of endurance training on ventilation, blood lactate and plasma potassium during incremental exercise. [s.l: The Author], 1996.

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14

Ostojic, Sandra. A study of the Michaelis constant for the H4 and M4 isoenzymes of lactate dehydrogenase. Sudbury, Ont: Laurentian University, 1994.

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15

Sada, Nagisa, and Tsuyoshi Inoue. Lactate Dehydrogenase. Edited by Detlev Boison. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0029.

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Glucose is transported into neurons and used as an energy source. It is also transported into astrocytes, a type of glial cell, and converted to lactate, which is then released to neurons and used as another energy source. The latter is called the astrocyte-neuron lactate shuttle. Although the lactate shuttle is a metabolic pathway, it also plays important roles in neuronal activities and brain functions. We recently reported that this metabolic pathway is involved in the antiepileptic effects of the ketogenic diet. Lactate dehydrogenase (LDH) is a metabolic enzyme that mediates the lactate shuttle, and its inhibition hyperpolarizes neurons and suppresses seizures. This enzyme is also a molecular target of stiripentol, a clinically used antiepileptic drug for Dravet syndrome. This review provides an overview of electrical regulation by the astrocyte-neuron lactate shuttle, and then introduces LDH as a metabolic target against epilepsy.
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16

Peter, M. D. Janssen. Lactate Threshold Training. Human Kinetics Publishers, 2001.

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17

Anderson, Owen. Lactate lift-off. SSS Pub, 1998.

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18

Training Lactate Pulse-Rate. Polar Electro, 1987.

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19

Jansen, Tim C., and Jan Bakker. Lactate monitoring in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0139.

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An increased blood lactate level (hyperlactataemia) is commonplace in critically-ill patients. Lactate is usually measured with the aim of detecting tissue hypoxia, but this is an oversimplification as aerobic processes can also result in increased levels. Understanding of the various anaerobic and aerobic mechanisms of production and clearance is essential for the correct interpretation of hyperlactataemia. Despite the broad differential diagnosis, hyperlactataemia generally predicts adverse outcomes. The consistency of its prognostic value emphasizes its place in the risk stratification of critically-ill patients. Lactate clearance was non-inferior to central venous oxygen saturation as a goal of early resuscitation in patients presenting to the emergency department with severe sepsis or septic shock. Therapy guidance by lactate monitoring significantly reduced hospital mortality in ICU patients admitted with hyperlactataemia after adjustment for predefined risk factors, a finding consistent with important secondary endpoints. These results confirm that lactate monitoring offers clinical benefit and should be incorporated within a goal-directed therapy strategy.
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20

Blokdijk, G. J. Sodium Lactate; A Complete Guide. CreateSpace Independent Publishing Platform, 2018.

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21

Chang, Jiang. Gender differences in peak blood lactate concentration and blood lactate removal following strenuous exercise. 1992.

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22

Jiang, Chang. Gender differences in peak blood lactate concentration and blood lactate removal following strenuous exercise. 1991.

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23

Gender differences in peak blood lactate concentration and blood lactate removal following strenuous exercise. 1991.

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24

J, Weber, H. Denolin, P. R. Moret, and J. C. Haissly. Lactate: Physiologic, Methodologic and Pathologic Approach. Springer London, Limited, 2012.

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25

Kumar, Vinita. Lactate Dehydrogenase: Biochemistry, Function and Clinical Significance. Nova Science Publishers, Incorporated, 2019.

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26

Rani, Reshma. Lactate Dehydrogenase: Biochemistry, Function and Clinical Significance. Nova Science Publishers, Incorporated, 2019.

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27

samuel, ramon. Lactaid Fast Act Lactose Intolerance Relief Caplets: Bactose Probiotics Digest Lactose - Produces Lactase. Independently Published, 2022.

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28

Determination of the lactate threshold by respiratory gas exchange measures and blood lactate levels during incremental-load work. 1989.

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29

Determination of the lactate threshold by respiratory gas exchange measures and blood lactate levels during incremental-load work. 1989.

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30

Determination of the lactate threshold by respiratory gas exchange measures and blood lactate levels during incremental-load work. 1987.

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31

Lambert, Karen, Bisbal Catherine, Philippe Connes, and Luc Pellerin, eds. Lactate as a Major Signaling Molecule for Homeostasis. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-474-7.

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32

Blood lactate responses for three competitive swimming strokes. 1988.

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33

Blood lactate responses for three competitive swimming strokes. 1990.

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34

Validation of equations to predict lactate threshold, fixed blood lactate concentrations, and peak values from a 3200 meter performance time. 1991.

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35

Stanley, William C. Lactate kinetics in man at rest and during exercise. 1986.

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36

Stanley, William C. Lactate kinetics in man at rest and during exercise. 1986.

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37

Stanley, William C. Lactate kinetics in man at rest and during exercise. 1986.

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38

Stanley, William C. Lactate kinetics in man at rest and during exercise. 1990.

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39

The objectivity and reproducibility of the lactate and ventilatory breakpoints. 1989.

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40

The relationship between muscle fiber type and serum lactate dehydrogenase. 1988.

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41

Effect of training on lactate utilization by rat muscle mitochondria. 1989.

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42

Comparison of the lactate and ventilatory thresholds during prolonged work. 1991.

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43

Effect of training on lactate utilization by rat muscle mitochondria. 1990.

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44

The objectivity and reproducibility of the lactate and ventilatory breakpoints. 1990.

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45

Plasma and erythrocyte lactate concentrations in humans after submaximal exercise. 1990.

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46

Comparison of the lactate and ventilatory thresholds during prolonged work. 1991.

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47

Plasma and erythrocyte lactate concentrations in humans after submaximal exercise. 1992.

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48

Comparison of the lactate and ventilatory thresholds during prolonged work. 1991.

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49

The determination of the lactate and ventilatory thresholds in the aged. 1988.

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50

Variations in the ventilatory and lactate thresholds with prolonged aerobic exercise. 1986.

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