Relevant bibliographies by topics / Lactate

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  2. Dissertations / Theses
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Academic literature on the topic 'Lactate'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 July 2024

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Journal articles on the topic "Lactate"

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Opdahl, Lee J., Ricky W. Lewis, Lee A. Kalcsits, Tarah S. Sullivan, and Karen A. Sanguinet. "Plant Uptake of Lactate-Bound Metals: A Sustainable Alternative to Metal Chlorides." Biomolecules 11, no. 8 (July 23, 2021): 1085. http://dx.doi.org/10.3390/biom11081085.

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Global agricultural intensification has prompted investigations into biostimulants to enhance plant nutrition and soil ecosystem processes. Metal lactates are an understudied class of organic micronutrient supplement that provide both a labile carbon source and mineral nutrition for plant and microbial growth. To gain a fundamental understanding of plant responses to metal lactates, we employed a series of sterile culture-vessel experiments to compare the uptake and toxicity of five metals (Zn, Mn, Cu, Ni, and Co) supplied in lactate and chloride salt form. Additionally, primary root growth in plate-grown Arabidopsis thaliana seedlings was used to determine optimal concentrations of each metal lactate. Our results suggest that uptake and utilization of metals in wheat (Triticum aestivum L.) when supplied in lactate form is comparable to that of metal chlorides. Metal lactates also have promotional growth effects on A. thaliana seedlings with optimal concentrations identified for Zn (0.5–1.0 µM), Mn (0.5–1.0 µM), Cu (0.5 µM), Ni (1.0 µM), and Co (0.5 µM) lactate. These findings present foundational evidence to support the use of metal lactates as potential crop biostimulants due to their ability to both supply nutrients and stimulate plant growth.
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Nikseresht, Asghar, Iman Yabande, Karamatollah Rahmanian, and Abdolreza Sotoodeh Jahromi. "Blood lactate level in Elite boy swimmers after lactate tolerance exercise test." Biomedical Research and Therapy 4, no. 05 (May 22, 2017): 1318. http://dx.doi.org/10.15419/bmrat.v4i05.170.

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Introduction: To avoid injuries during high-intensity sports training, it is important to recognize conditions of bodily consumption and production of adequate energy; exercise increases the concentration of the blood lactate. This paper is an attempt to compare pre and post lactate tolerance exercise test - blood lactate concentrations - of elite boy swimmers. Methods: Blood lactates are measured by an enzymatic method on 12 subjects 30 minutes before and adjust and 24 hours after the test. Results: The mean lactate concentration of 30.35±12.16 mg/dl is observed in swimmers 30 minutes before the test. Swimmers adjust after the test show mean blood lactate concentration of 108.52±18.17 mg/dl that is significantly higher than 30 minutes before the test (p<0.001). Then blood lactate level decreases below baseline level at 24 hours after the test. Conclusion: Blood lactate increases with the test and decreases below baseline within 24 hours after the test.
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Zitek, Tony, Zachary D. Skaggs, Aryan Rahbar, Jayme Patel, and Memona Khan. "Does Intravenous Lactated Ringer’s Solution Raise Serum Lactate?" Journal of Emergency Medicine 55, no. 3 (September 2018): 313–18. http://dx.doi.org/10.1016/j.jemermed.2018.05.031.

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Shephard, R. J. "Evaluation of three portable blood lactate analysers: Lactate Pro, Lactate Scout and Lactate Plus." Yearbook of Sports Medicine 2011 (January 2011): 153–54. http://dx.doi.org/10.1016/s0162-0908(10)79751-8.

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Tanner, Rebecca K., Kate L. Fuller, and Megan L. R. Ross. "Evaluation of three portable blood lactate analysers: Lactate Pro, Lactate Scout and Lactate Plus." European Journal of Applied Physiology 109, no. 3 (February 10, 2010): 551–59. http://dx.doi.org/10.1007/s00421-010-1379-9.

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Balakrishnan, Vamsi, John Wilson, Brent Taggart, James Cipolla, and Rebecca Jeanmonod. "Impact of Phlebotomy Tourniquet Use on Blood Lactate Levels in Acutely Ill Patients." CJEM 18, no. 5 (February 11, 2016): 358–62. http://dx.doi.org/10.1017/cem.2016.6.

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AbstractObjectiveLactate levels are increasingly used to guide resuscitation efforts. Some surgical literature suggests that tourniquet use during phlebotomy falsely elevates results, although studies in healthy volunteers have not demonstrated this. The purpose of this study was to determine in clinical practice whether tourniquet use during the drawing of a lactate results in significantly altered levels compared to the result of a level drawn without a tourniquet.MethodsA prospective cohort study was carried out on emergency department patients whose clinical presentation led a physician to order a lactate level. Written informed consent was obtained from patients or their proxies. Study lactates were obtained using a tourniquet during the draw sequence of other laboratory studies. Lactate levels for clinical use were drawn per hospital protocol with no tourniquet. The time of lactate measurements and patient demographic information were recorded. Lactate levels for each patient were compared with the Wilcoxon Rank-Sum Test.Results40 patients were consented and enrolled. The median clinical lactate level was 1.9 (interquartile range 1.5-2.6), and the median study lactate level was 1.9 (interquartile range 1.4-2.7). There was no difference between paired lactate values (p=0.95).ConclusionsTourniquet use appears to have no impact on measured lactate levels. Our findings suggest that current practices at many institutions regarding lactate collection are likely too stringent and should be changed.
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Wu, Yuhan, Hui Hu, Weiwei Liu, Yun Zhao, Fang Xie, Zhaowei Sun, Ling Zhang, Huafeng Dong, Xue Wang, and Lingjia Qian. "Hippocampal Lactate-Infusion Enhances Spatial Memory Correlated with Monocarboxylate Transporter 2 and Lactylation." Brain Sciences 14, no. 4 (March 28, 2024): 327. http://dx.doi.org/10.3390/brainsci14040327.

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Lactate has emerged as a key player in regulating neural functions and cognitive processes. Beyond its function as an energy substrate and signal molecule, recent research has revealed lactate to serve as an epigenetic regulator in the brain. However, the molecular mechanisms by which lactate regulates spatial memory and its role in the prevention of cognitive disorders remain unclear. Herein, we injected L-lactate (10 μmol/kg/d for 6 d) into the mouse’s hippocampus, followed by the Morris water maze (MWM) test and molecular analyses. Improved spatial memory performances were observed in mice injected with lactate. Besides, lactate upregulated the expression of synaptic proteins post-synaptic density 95 (PSD95), synaptophysin (SYP), and growth associated protein 43 (GAP43) in hippocampal tissues and HT22 cells, suggesting a potential role in synaptic transmission and memory formation. The facilitative role of monocarboxylate transporter 2 (MCT2), a neuron-specific lactate transporter, in this process was confirmed, as MCT2 antagonists attenuated the lactate-induced upregulation of synaptic proteins. Moreover, lactate induced protein lactylation, a post-translational modification, which could be suppressed by MCT2 inhibition. RNA sequencing of lactated-injected hippocampal tissues revealed a comprehensive gene expression profile influenced by lactate, with significant changes in genes associated with transcriptional progress. These data demonstrate that hippocampal lactate injection enhances spatial memory in mice, potentially through the upregulation of synaptic proteins and induction of protein lactylation, with MCT2 playing a crucial role in these processes. Our findings shed light on the multi-faceted role of lactate in neural function and memory regulation, opening new avenues for therapeutic interventions targeting cognitive disorders.
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Brooks, George A. "Lactate." Sports Medicine 37, no. 4 (2007): 341–43. http://dx.doi.org/10.2165/00007256-200737040-00017.

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Gollnick, Philip D. "LACTATE." Medicine & Science in Sports & Exercise 17, no. 2 (April 1985): 258. http://dx.doi.org/10.1249/00005768-198504000-00342.

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Tomis, Claire, and Anne Vassault. "Lactate." EMC - Biologie Médicale 1, no. 1 (January 2006): 1–4. http://dx.doi.org/10.1016/s2211-9698(06)76089-7.

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Dissertations / Theses on the topic "Lactate"

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Weihrer, Sylvia J. "Changes in blood lactate concentration during active recovery at sub-lactate threshold, lactate threshold, and supra-lactate threshold exercise intensities." Thesis, University of Ottawa (Canada), 1991. http://hdl.handle.net/10393/7892.

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The purpose of this investigation was to identify the intensity of recovery exercise, relevant to endurance event performance, that would result in the most rapid times for half decrease in blood lactate concentration, following 2 minutes of cycling at maximal rates. Three recovery exercise intensities were investigated: (a) 7% of the maximal rate of oxygen consumption (VO$\sb2$) (LT $-$7%), (b) lactate threshold VO$\sb2$ ( LT), and (c) 7% of VO$\sb2$max above lactate threshold VO$\sb2$ (LT +7%). Seven well-trained male cyclists (mean VO$\sb2$max 4.6 $\pm$ 0.49 L $\times$ min$\sp{-1}$ participated as subjects in the investigation. Each subject completed seven separate cycling tests: (a) one combined lactate threshold-VO$\sb2$max test, (b) three constant work rate tests, and (c) three tests of recovery following supra-lactate threshold exercise (surge-recovery tests). The absolute values of blood lactate concentration were significantly different across the three recovery intensities (p .01). At the end of the 20 minute recovery period the mean blood lactate concentrations were 1.57, 2.49, and 4.17 mmol $\times$ L$\sp{-1}$ for the LT $-$7%, LT%, and LT +7% recovery intensities, respectively. Times for half decrease in blood lactate concentration were calculated. There were no significant differences in these half decrease times between the three recovery intensities (p .01). (Abstract shortened by UMI.)
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Lowinsohn, Denise. "Desenvolvimento de um sensor para análise de lactato em amostras alimentares e biológicas." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/46/46133/tde-14082007-111340/.

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Neste trabalho são apresentados resultados relacionados a estudos sobre o comportamento eletroquímico do lactato e do peróxido de hidrogênio em diversos eletrodos em meio de diferentes pHs utilizando voltametria cíclica. Também foi investigado o comportamento eletroquímico do peróxido de hidrogênio em eletrodos modificados com filmes de hexacianoferratos utilizando eletrodos de platina e carbono vítreo. A vantagem do uso do CTAB na modificação da superfície de carbono vítreo com Azul da Prússia foi confirmada no que se refere à melhora da sensibilidade e da estabilidade das medidas. Numa etapa posterior desenvolveu-se um biossensor para a determinação de lactato pelo monitoramento de peróxido de hidrogênio produzido na reação catalisada de lactato com oxigênio na presença da enzima lactato oxidase. Nessa etapa, o trabalho consistiu em imobilizar a enzima lactato oxidase na superfície do eletrodo, previamente, modificado com Azul da Prússia, com o auxílio de Nafion®. Após a construção do biossensor e a otimização das condições de análise (pH, quantidade de enzima, volume da amostra e vazão) para obtenção de maior sinal analítico no desenvolvimento do método para a determinação de lactato por análise em fluxo, averiguou-se a repetibilidade das medidas (Clactato = 0,28 mmol L-1) obtendo-se um desvio padrão de 2,2% para 18 repetições. A freqüência analítica foi estimada em 160 injeções por hora com limite de detecção de 0,84 µmol L-1 e linearidade até 0,28 mmol L-1 de lactato. O biossensor foi aplicado na quantificação de lactato em amostras alimentares (cervejas alcoólicas e não alcoólicas) e biológicas (sangue liofilizado e recém coletado). Por fim, realizaram-se estudos envolvendo a variação da concentração de lactato sanguíneo em função da intensidade de atividade esportiva. Os resultados obtidos pelo método proposto foram comparados com aqueles oriundos do uso de método de referência.
Results on the investigation of the electrochemical behavior of lactate and hydrogen peroxide at various electrodic surfaces at different pHs using cyclic voltammetry are presented. Experiments were also carried out with platinum and glassy carbon electrodes modified with hexacyanoferrate films. The advantage of using CTAB in the electrodeposition step of Prussian Blue films onto glassy carbon surfaces was confirmed taking into account both the stability and sensitivity of measurements. The immobilization of lactate oxidase onto glassy carbon electrodes modified with a Prussian Blue layer using Nafion® was performed to fabricate a biosensor for lactate. The biosensor was used in the development of a FIA amperometric method for the determination of lactate. Under optimal operating conditions (pH = 6.9, E = -0.1 V), the linear response of the method was extended up to 0.28 mmol L-1 lactate with a limit of detection of 0.84 µmol L-1. The repeatability of the method for injections of a 0.28 mmol L-1 lactate solution was 2.2 % (n = 18). The analytical frequency was calculated as 160 injections h-1. The usefulness of the method was demonstrated by determining lactate in beer (alcoholic and nonalcoholic beers) and blood samples (lyophilized and freshly collected). Finally, the influence of physical exercise on the blood lactate level was studied. Results obtained by using the proposed amperometric detector compared well with the reference method.
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Feringer, Júnior Walter Heinz [UNESP]. "Expressão dos transportadores de monocarboxilatos de equinos e cães." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/153171.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
O principal mecanismo de transporte dos íons lactato e H+ em equinos e cães é o complexo transportador formado pelos transportadores de monocarboxilatos, isoformas 1 (MCT1) e 4 (MCT4) juntamente com a proteína auxiliar CD147. Objetivando identificar diferenças entre equinos com desempenho distinto, 16 equinos da raça Brasileiro de Hipismo (BH) foram distribuídos em dois grupos, desempenho inferior (DI, n=8) e desempenho superior (DS, n=8) que foram submetidos a teste de salto incrementai (TSI). Realizou-se biópsia do músculo Gluteus medius para tipificação e análise das expressões das isoformas MCT1, MCT4 e CD147. Amostras sanguíneas foram colhidas para avaliar as expressões MCT1 e CD147 das hemácias. Aplicaram-se testes de normalidade de Shapiro Wilk e homogeneidade de Levene. As medidas morfométricas foram submetidas ao teste de Tukey. Teste “t” de Student não pareado para a comparação das médias dos grupos DI e DS. Aplicou-se correlação de Spearman para as expressões dos transportadores. Para todas as análises utilizou-se p≤0,05. Não houve diferença entre os grupos quanto à frequência de cada tipo de fibra e constatou-se maior quantidade das fibras tipo I em relação às fibras IIA e IIX em todos os equinos avaliados. Não houve diferença entre os pesos moleculares e a expressão das proteínas MCT1, MCT4, e CD147 musculares ou sanguíneas. Houve correlações positivas entre MCT1 vs. CD147 e MCT4 vs. CD147 musculares dos grupos DI e DS. As correlações encontradas foram esperadas uma vez que as isoformas estudadas dependem intimamente da proteína auxiliar CD147 para o transporte. Os equinos BH não apresentaram diferenças nas expressões dos MCT1,4 e CD147, musculares ou sanguíneos, mesmo com níveis de condicionamento diferentes. Com o objetivo de investigar as concentrações de lactato plasmático e das hemácias e avaliar as expressões eritrocitáras do complexo transportador MT1/CD147, 6 cães da raça American Pitbull Terrier (APBT) foram submetidos ao teste de esforço incremental (TEI) em esteira. No final de cada incremento de velocidade foi coletado sangue da veia cefálica. Foram mensuradas concentrações de lactato sanguíneo (LS), plasmático (LP), pH e hematócrito (Ht). A concentração do lactato dentro das hemácias (LH) foi estimada e estabeleceu-se a relação LH:LP. As expressões sanguíneas do complexo MCT1/CD147 foram avaliadas por Western Bloting. Aplicou-se análise de variância de uma via seguido pelo teste de Dunn’s. Para pH e Ht aplicou-se teste t de student para amostras pareadas e a correlação de Pearson foi utilizada para MCT1 e CD147, estabeleceu-se nível de significância P≤0,05. LS, LP e LH e pH não apresentaram diferenças entre si, a relação LH:LP foi próxima de 1 com tendência de aumento. MCT1 e CD147 apresentaram 48 e 59 kDa de peso molecular e 1,27 e 1,05 de unidades ópticas arbitrárias (UOA). Não foram encontradas correlações entre MCT1 e CD147. A grande velocidade de transporte do MCT1/CD147 explica a relação LP:LH próxima de 1, esta velocidade e o mecanismo de arquejo podem explicar os valores de pH constantes. A raça APBT, quando submetidos à atividade física apresentaram tendência de aumento da relação LH:LP e expressam de maneira homogênea o complexo MCT1/CD147.
The central transport mechanism of lactate and H+ ions in horses and dogs is the carrier complex formed by the monocarboxylate, isoform 1 (MCT1) and 4 (MCT4) associated with the ancillary protein CD147. This study aimed to identify possible differences between horses with different performances levels, 16 horses of the Brazilian Sport Horse breed (BH) were distributed in two groups, inferior performance (IP, n = 8) and superior performance (SP, n = 8). A Gluteus medius muscle biopsy was performed for cellular typing and analysis of MCT1, MCT4, and CD147 muscle expressions. By jugular venipuncture, blood samples were collected to evaluate MCT1 and CD147 expressions in the red blood cells (RBC). Normality Shapiro Wilk test and homogeneity of Levene were applied. The morphometric measurements were submitted to the Tukey test, and not paired Student's t-test were applied to compare the mean of the IP and SP groups for all variables and was used Spearman's correlation for isoform expressions, for all analyzes, p≤0.05. There were no differences between the groups regarding the frequency of each type of fiber and a higher number of type I fibers were observed about the IIA and IIX fibers in all groups. There was no difference between molecular weights and expressions of MCT1, MCT4, and CD147 in muscle or blood. There were positive correlations between muscles MCT1 vs CD147 and MCT4 vs CD147 in both groups. The relationships found were expected since the MCT1 and 4 depended on the CD147 ancillary protein for correct functioning. The BH horses do not present differences in the muscle or RBC expressions of MCT1, 4 and CD147, even with different conditioning levels. To investigate plasma and erythrocyte lactate concentrations and to evaluate erythrocyte expression of the MT1/CD147 transporter complex, six dogs of the American Pit Bull Terrier breed (APBT) were submitted to a treadmill incremental effort test (IET). At the end of each increment of speed, blood was collected from the cephalic vein. Concentrations of blood (BL) and plasma lactate (PL), pH and hematocrit (Ht) were measured. The concentration of lactate inside the red blood cells (LC) was estimated and the LC: PL ratio was established, the blood expressions of the MCT1/CD147 transporter complex were evaluated by western blot. Data were submitted to the Shapiro-Wilks normality test, one-way ANOVA and Dunn's test. For pH and Ht, paired Student's t-test was applied, and Pearson's correlation was used for MCT1 and CD147 analysis, for all analyzes, p≤0.05. BL, PL, LC, pH showed no differences, the LC: PL ratio was close to 1 with an increasing tendency. MCT1 and CD147 presented 48 and 59 kDa of molecular weight and 1.27 and 1.05 of arbitrary optical units (AOU). No correlations were found between MCT1 and CD147. The high transport velocity of the MCT1/CD147 could explain the LC: PL ratio close to 1, this velocity plus the grasping mechanism may explain the constant of pH values. The APBT submitted to intense physical activity showed a tendency to increase the LC: PL ratio, and homogeneously express the MCT1/CD147 complex
FAPESP: 11/11080-0
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Nel, Mirinda. "Serum lactate in canine babesiosis." Diss., University of Pretoria, 2005. http://hdl.handle.net/2263/22944.

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Canine babesiosis typically causes a haemolytic anemia and results in hypoxia and sepsis, which can eventually result in multiple organ dysfunction. Human patients with severe injury or disease such as shock, sepsis and malaria often have persistent hyperlactataemia, and there is a correlation between blood lactate and survival rate. There are various similarities between human malaria and canine babesiosis, eg. anaemia, renal failure, cerebral forms, coagulopathy, hepatopathy, pulmonary oedema, and shock. In severe malaria, lactate levels in blood rise in direct proportion to the severity of the disease. Venous lactate concentrations measured at 4 hours after admission appears to be the best prognostic indicator in severe malaria. In dogs blood lactate has been shown to be of prognostic value in patients with gastric dilatationvolvulus and in dogs admitted to intensive care units. Blood lactate has also been shown to be of prognostic value in equine colic. Blood lactate was determined in ninety dogs with naturally occurring canine babesiosis. Forty-five dogs (50%) presented with hyperlactataemia (blood lactate > 2.5mmol/L) and 20 (22.2%) with hypoglycaemia (blood glucose < 3.3 mmol/L). Measurements significantly associated with mortality were hypoglycaemia on admission, blood lactate > 5mmol/L on admission, blood lactate > 2.5 mmol/L at 8, 16 and 24 hours after admission, and increase or < 50% decrease in blood lactate within 8 and 16 hours after admission. Blood lactate persistently > 4.4 mmol/L indicated a very poor prognosis. The study concluded that serial blood lactate measurements are useful in predicting survival in dogs with severe and complicated canine babesiosis.
Dissertation (MMed Vet (Med))--University of Pretoria, 2004.
Companion Animal Clinical Studies
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Buckley, Jonathan David. "Human lactate kinetics : training effects /." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phb924.pdf.

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Preneta, A. Z. "Studies on lactate oxidising enzymes and their application to ferrocene-based enzyme electrodes for lactate." Thesis, Cranfield University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376191.

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Soares, Otávio Augusto Brioschi [UNESP]. "Comparação de diferentes métodos lactacidêmicos e glicêmicos de determinação do limiar anaeróbio em eqüinos." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/89221.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O esporte eqüestre vem exigindo um grau crescente de profissionalismo no mundo todo. Testes de desempenho, como a aferição do Limiar anaeróbio (LA), inserem-se neste contexto. Este trabalho comparou sete protocolos de mensuração do LA, cinco lactacidêmicos (V2, V4, LAI, LAI0,5, Lacmin) e dois glicêmicos (LGI e Glicmin). Todos foram comparados a Máxima fase estável do lactato (MFEL), protocolo padrão de aferição do LA. Catorze eqüinos Puro Sangue Árabe foram utilizados, entre machos e fêmeas. As médias e desvios-padrão das velocidades associadas aos testes foram: V2 = 9,49 ± 0,83 m/s, V4 = 10,83 ± 0,71 m/s, VLAI = 9,62 ± 0,91 m/s, VLAI0,5 = 10,21 ± 0,80 m/s, VLacmin = 7,49 ± 0,55 m/s, VLGI = 7,69 ± 1,68 m/s, VGlicmin = 8,31 ± 1,64 m/s e VMFEL = 6,06 ± 0,51 m/s. Somente a VLacmin não diferiu da VMFEL, além de obter correlação significativa com a mesma de ρ = 0,76 (Correlação de Spearman). A Tendência e os Limites de Concordância entre a VLacmin e a VMFEL foram de 1,43; 0,79 e 2,05. Além de predizer velocidades diferentes da VMFEL, os limiares LAI, LGI e Glicmin apresentaram dificuldades operacionais. As diferenças entre as velocidades preditas pelos protocolos V2, V4, LAI e LAI0,5, LGI e Glicmin a VMFEL podem ser parcialmente explicadas por variações de composição de protocolo e dificuldades operacionais. Apesar de não diferirem estatisticamente, as VLacmin e as VMFEL apresentaram baixa concordância, o que provavelmente pode ser melhorado com ajustes finos no protocolo do Lacmin.
Equestrian sports are demanding a growing degree of professionalism all over the world. Performance tests, as Anaerobic threshold (AT) assessment, are inserted in that context. The present study compared seven protocols for anaerobic threshold assessment: five of them using the lactacidemia (V2, V4, IAT, IAT0.5 and Lacmin) and two glicemia (IGT and Glicmin). All of them were compared to the Maximal Lactate Steady State (MLSS), the gold standard for AT assessment. Fourteen Arabian horses, males and females were submitted to the protocols. Velocity means and standard deviation associated to each protocol were: V2 = 9.49 ± 0.83; V4 = 10.83 ± 0.71; VIAT = 9.62 ± 0.91; VIAT0,5 = 10.21 ± 0.80; VLacmin = 7.49 ± 0.55; VIGT = 7.69 ± 1.68; VGlicmin = 8.31 ± 1.64 e VMLSS = 6.06 ±0.51. Only VLacmin did not differ from VMLSS, moreover, they correlate significantly with ρ = 0.76 (Spearman correlation). Bias ant Limits of Agreement of the two methods were 1.43; 0.79 and 2.05. Besides they predicted different velocities when compared to VMLSS, IAT, IGT and Glicmin showed operational difficulties. The differences between the velocities associated with the several protocols and the VMLSS could be partially attributed to protocol components variations and some operational difficulties. Regardless the statistical equality, VLacmin and VMLSS revealed poor agreement, what could probably be improved with adjustments in the Lacmin protocol.
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Barros, Luis Fernando Nogueira Paes de. ""Limiar de lactato em teste de quadra: validade em jogadores de futsal"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/39/39132/tde-13072006-111624/.

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O objetivo deste estudo foi a validação da medida de limiar anaeróbio com o teste escalonado intermitente de 20 m de ida-e-volta em quadra, comparando-o com teste escalonado em esteira e com o máximo “steady state” de lactato (MLSS) em teste retangular simulado, em jogadores de Futsal. Para isso, nove jogadores de Futsal (16,8 ± 1,27 anos) realizaram um teste incremental em esteira (protocolo de HECK, 1985) para determinação da velocidade de 3,5 mmol.l-1 de lactato (V3,5Heck). Também para determinação da V3,5 (V3,5leger), os atletas realizaram teste progressivo de 20 m de ida-e-volta, com velocidade inicial de 8,5 km.h-1, com incremento de 1 km.h-1 a cada três minutos. Após a determinação da V3,5leger, os atletas retornaram à quadra e realizaram (pelo menos) três testes para a determinação do MLSS. O MLSS foi determinado através de corrida intermitente (20 m de ida-e-volta) e definido como a maior velocidade em que o lactato sanguíneo não aumentou mais que 1 mmol.l-1 de lactato entre o 10 e 30 minutos com velocidade constante. As velocidades correspondentes à V3,5leger e MLSS tiveram correlação de r = 0,86. O teste de comparações múltiplas TURKEY TEST detectou que existe diferença (p<0,05) entre as médias de intensidade de MLSS e V3,5Heck e entre V3,5Heck e V3,5leger. Já entre V3,5leger e MLSS, o teste não detectou diferença. A correlação entre a F.C. no V3,5leger e o MLSS foi de r = 0,70. O teste de comparações múltiplas TURKEY TEST detectou que existe diferença (p<0,05) entre as médias de F.C. entre V3,5leger e MLSS e entre V3,5Heck e MLSS. Já entre V3,5leger e V3,5Heck, o teste não detectou diferença. Portanto, nós concluímos que a V3,5leger é um instrumento válido para se estimar o MLSS em jogadores de Futsal.
The objective of this study was to investigate the validity of the anaerobic threshold in the 20 m shuttle run test in the determination of the maximal lactate steady state (MLSS) in Futsal players. Nine male futsal players (16,8 ± 1.27 years) performed an incremental treadmill test for the determination of the velocity corresponding of 3.5 mmol.l-1 of lactate (HECK et alii, 1985) (V3.5Heck). Also for the determination of the V3.5 (V3.5leger), the Futsal players performed the 20 m shuttle run test, with the initial running speed of 8.5 km.h-1 and increment of 1 km.h-1 each three minutes. After the determination of the V3.5 the athletes performed at least three tests to determine the MLSS. The MLSS was determined through intermittent running (20 m shuttle run) and defined as the highest velocity at which blood lactate did not increase by more than 1 mmol.l-1 between the minutes 10 and 30 of the constant velocity runs. There was a significant correlation between the velocities of V3.5leger and MLSS (r = 0.86). Analysis of variance revealed significant difference (p<0.05) between the intensities of the MLSS and V3.5Heck and between V3.5Heck e V3.5leger, but the analysis did not reveal difference between V3.5leger and the MLSS. The correlation between the heart frequency (F.C.) in the V3.5 Leger and MLSS was r=0.70. The analysis of variance revealed significant differences (p<0.05) between F.C. in V3.5leger and MLSS and between V3.5Heck and MLSS. The analysis did not revealed differences between V3.5leger and V3.5Heck. We conclude that OBLA can be utilized in Futsal players to estimate the MLSS.
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Funari, Sabrina. "Avaliação da suplementação com dimetilglicina sobre o desempenho atlético de cavalos de enduro." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-29082012-160647/.

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O exercício de enduro é caracterizado por um esforço aeróbico prolongado, de intensidade variável em que o cavalo é submetido a um trabalho permanente o qual exige dos sistemas orgânicos a manutenção da homeostasia. A habilidade dos músculos em gerar energia rapidamente via produção de lactato, é essencial para o desempenho em exercícios de elevada intensidade. Entretanto, a produção de lactato pode também suprimir muitos dos processos vitais necessários pra sustentar a atividade muscular. A associação de lactato com a fadiga muscular tem levado à busca de suplementos alimentares que reduzem o acúmulo de lactato. N,N-Dimetilglicina (DMG), um intermediário do metabolismo da colina, é um suplemento atualmente comercializado, porém não há dados consistentes na literatura sobre sua eficácia para equinos atletas. Objetivando avaliar o efeito da DMG, utilizou-se 12 animais em treinamento para provas de enduro, dos quais seis receberam suplementação oral; utilizou-se delineamento inteiramente casualizado, com medidas repetidas no tempo. Foram coletadas amostras de sangue em sete tempos diferentes, a cada 15 dias; dessas amostras obteve-se valores das enzimas creatina quinase e aspartato aminotransferase e também valores de glicose e lactato, além de medições de freqüência cardíaca e respiratória. Após 30 dias da última amostragem, realizaram-se coletas de sangue em intervalos curtos de tempo, após exercício, a fim de se realizar uma curva de lactato, e também comparar dados analisados em laboratório com analisados via lactímetro. Dos dados analisados, houve interação entre tempo e aumento da enzima creatina quinase, o que pode ser justificado pelo aumento da demanda muscular durante exercício físico constante. A enzima aspartato aminotransferase diminuiu com o passar do tempo, em ambos os grupos, porém oscilou dentro da normalidade, o que pode caracterizar baixa permeabilidade da membrana celular, comum em animais condicionados. A alteração da glicose foi a mesma ao longo do tempo para ambos os grupos. As médias de lactato não diferiram no grupo suplementado, mas sua variação dentro do grupo não suplementado sugere que a suplementação com DMG pode influenciar na manutenção da integridade muscular. Em comparação entre as formas de dosagem do lactato plasmático, pode-se concluir que o lactímetro é uma ferramenta eficaz na obtenção de dados a campo, pois suas médias não diferiram das médias de lactato obtidas através de análise laboratorial. A suplementação oral com dimetilglicina não influenciou o desempenho atlético de cavalos em treinamento para enduro equestre.
The exercise endurance is characterized by a prolonged aerobic work, of varying intensity in which the horse is subjected to a permanent job which requires organ systems maintain homeostasis. The ability of muscles to generate energy quickly via production of lactate is essential for the performance of high intensity exercise. However, the production of lactate may also suppress many of the vital processes necessary to sustain muscle activity. The combination of lactate in muscle fatigue has led to the search for dietary supplements that reduce the accumulation of lactate. N, N-dimethylglycine (DMG), an intermediate in the metabolism of choline, is a supplement currently marketed, but there is no consistent data in the literature on its effectiveness for equine athletes. In order to evaluate the effect of DMG, we used 12 animals in training for endurance events, of which six received oral supplementation, we used a completely randomized design with repeated measures on time. Blood samples were collected in seven different times, every 15 days, these samples gave values of the enzymes creatine kinase and aspartate aminotransferase values as well as glucose and lactate, and easurements of heart rate and breathing. After 30 days the last sampling, there were blood samples at short intervals of time after exercise in order to perform a lactate curve, and also compare data analyzed in laboratory and analyzed via lactimeter. Of the data analyzed, there was interaction between time and increased the enzyme creatine kinase, which can be explained by increased demand constant muscle during exercise. The enzyme aspartate aminotransferase decreased over time in both groups, but varied within the normal range, which can characterize low permeability of the cell membrane, which is common in animals conditioned. The change in glucose was the same over time for both groups. The mean lactate did not differ in the supplemented group, but the variation in the unsupplemented group suggests that supplementation with DMG can influence the maintenance of muscle integrity. In comparison dosage forms of lactate, it can be concluded that the lactimeter is an effective tool for getting data into the field, because their means did not differ from average lactate obtained through laboratory analysis. Oral supplementation with dimethylglicine did not influence athletic performance of horses in training for endurance riding.
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Costa, Samuel André Bailador. "Maneio do paciente politraumatizado na clínica de animais de companhia." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2014. http://hdl.handle.net/10400.5/7577.

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Dissertação de Mestrado Integrado em Medicina Veterinária
Resumo: O politraumatismo consiste em múltiplas lesões orgânicas causadas por um mesmo acidente, com pelo menos uma delas a causar risco de vida. A pesquisa bibliográfica pretende demonstrar a importância da abordagem de urgência nestes pacientes segundo o ABCDE, que é o sistema universalmente aceite para diagnosticar e corrigir estas lesões e também da correta monitorização para evitar as complicações que surgem mais frequentemente. São também abordados os tipos de trauma mais importantes e o tratamento comum a todos. Finalmente são analisados os indicadores de trauma que dão uma noção da gravidade do processo e do prognóstico, permitindo a adoção de medidas precoces que visam reduzir a mortalidade. O estudo clínico realizado propõe a caraterização de uma população de pacientes politraumatizados principalmente quanto às suas causas mais frequentes e tipos de trauma. Para além disso é determinado o valor na triagem do lactato e, de forma inovadora, do índice de choque, como indicadores da mortalidade nesta população. Observou-se que o trauma cutâneo e músculo-esquelético apresentaram maiores prevalências, alertando a importância da deteção e correção destas lesões, para além das que causam risco de vida eminente. Mesmo com uma única medição na triagem, o lactato apresentou uma relação fiável com a mortalidade, sendo valores superiores a 6 mmol/L associados prognósticos mais reservados. O índice de choque não demonstrou uma correlação clara com a mortalidade sendo de interesse explorar mais a sua função como indicador do prognóstico.
ABSTRACT - MANAGEMENT OF POLYTRAUMA IN THE SMALL ANIMAL CLINICAL PRACTICE - Polytrauma refers to multiple organ systems injuries caused by a single accident, with at least one of them being life threatening. The bibliographic research intents to show the importance of the emergency approach to these patients according to the ABCDE witch is the universally accepted system to diagnose and correct these injuries. Additionally, there must be an adequate monitoring to avoid the complications witch frequently arise. The most important types of trauma and their common treatment are also mentioned. The indicators of trauma are finally analyzed, giving a notion of gravity and prognosis, allowing precocious measures to be taken to reduce mortality. The clinical study conducted characterizes a population of polytrauma patients by causes and types of trauma. In addition, lactate and innovatively, shock index, are determined as indicators of mortality in this population. Cutaneous and musculoskeletal were the most prevalent traumas, alerting the importance of detecting and correcting these lesions, besides the ones that are life threatening. Lactate was showed to be related with mortality in polytrauma even with a single measurement during triage, with values greater than 6 mmol/L associated with worst prognosis. Shock index didn’t show a clear correlation with mortality but it might be of interest to further explore its role as a prognostic indicator.
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Books on the topic "Lactate"

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Peter G. J. M. Janssen. Lactate threshold training. Champaign, IL: Human Kinetics, 2001.

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Janssen, Peter. Training lactate pulse rate. Oulu, Finland: Polar Electro Oy, 1989.

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The blood lactate response to exercise. Champaign, IL: Human Kinetics, 1995.

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Beaudoin, Marc. Glucose, lactate and lactate dehydrogenase levels in the human kidney carcinoma cell line A498 (ATCC HTB-44). Sudbury, Ont: Laurentian University, 1993.

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Boyce, Julian. Lactate dehydrogenase isoenzymes in malignant serous effusions. [s.l: The Author], 1989.

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Ogliaruso, Michael A. Synthesis of lactones and lactams. Chichester: Wiley, 1993.

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Lee, R. J. Lactic acid metabolism and lactate dehydrogenases of Vibrio species. Portsmouth: Portsmouth Polytechnic,School of Pharmacy..., 1987.

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Muldoon, Lori. Glucose, lactate, and lactate dehydrogenase activity of the small cell lung cancer line H-209 and the drug resistant variant H-209/V6. Sudbury, Ont: Laurentian University, 1992.

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Roberts, Philip Anthony. Differences in blood lactate concentrations as a measure of fitness between institute and club swimmers following a period of training: BA(Hons) Human Movement Studies dissertation. Cardiff: SGIHE, 1987.

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Urajnik, Diana J. The effects of lactate oxidase on human MCF7 breast cancer cells. Sudbury, Ont: Laurentian University, 1998.

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Book chapters on the topic "Lactate"

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Bährle-Rapp, Marina. "lactate." In Springer Lexikon Kosmetik und Körperpflege, 308. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_5749.

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Poblete, Glenn Hernández, Maarten W. Nijsten, and Jan Bakker. "Lactate." In Monitoring Tissue Perfusion in Shock, 131–42. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-43130-7_9.

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Castro, Ricardo, David Carpio, and Glenn Hernández. "Lactate." In Hemodynamic Monitoring, 191–201. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-69269-2_17.

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Bährle-Rapp, Marina. "Zinc Lactate." In Springer Lexikon Kosmetik und Körperpflege, 600. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_11313.

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Bährle-Rapp, Marina. "Butyl Lactate." In Springer Lexikon Kosmetik und Körperpflege, 79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_1426.

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Bährle-Rapp, Marina. "Calcium Lactate." In Springer Lexikon Kosmetik und Körperpflege, 82. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_1498.

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Bährle-Rapp, Marina. "Cetyl Lactate." In Springer Lexikon Kosmetik und Körperpflege, 99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_1813.

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Bährle-Rapp, Marina. "Chitosan Lactate." In Springer Lexikon Kosmetik und Körperpflege, 103. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_1885.

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Levraut, J., F. Lemoël, and T. Leplatois. "Le lactate." In Les biomarqueurs en médecine d’urgence, 171–77. Paris: Springer Paris, 2012. http://dx.doi.org/10.1007/978-2-8178-0297-8_22.

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Bährle-Rapp, Marina. "Stearyl Lactate." In Springer Lexikon Kosmetik und Körperpflege, 531. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_10060.

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Conference papers on the topic "Lactate"

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Miesse, Peyton, and Gymama Slaughter. "Flexible Electrochemical Lactate Biosensor." In 2020 IEEE 15th International Conference on Nano/Micro Engineered and Molecular System (NEMS). IEEE, 2020. http://dx.doi.org/10.1109/nems50311.2020.9265579.

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Tong Jijun, Hu Jie, Huang Zhongchao, Pan Min, and Chen Yuquan. "A Novel Lactate Biosensor." In 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. IEEE, 2005. http://dx.doi.org/10.1109/iembs.2005.1616391.

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Ramadan, L., J. Kaidbey, and J. Bakker. "Lactate Levels Require Context." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2909.

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Taertulakarn, Somchat, Adisorn Tuantranont, Pussadee Tobanluepop, and Chuchart Pintavirooj. "The preliminary study of lactate detection based on lactate dehydrogenase/nictotinamide adenine dinucleotide." In 2012 5th Biomedical Engineering International Conference (BMEiCON). IEEE, 2012. http://dx.doi.org/10.1109/bmeicon.2012.6465514.

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Rohrer, Amber, Daniel Conde, Samuel Montalvo, Manuel Gomez, Jennica Juarez, and Gabriel Ibarra-Mejia. "Changes in Lactate After the Completion of Repetitive Cycle Exercises with and without Compression Arm Sleeves." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1002617.

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Occupational compression sleeves are commonly used to relieve pain in the upper and lower extremities. Anecdotal data agree on the benefits of using compression sleeves while performing physical work. The purpose of this study was to assess the effects of wearing compression sleeves on the upper limbs on blood lactate concentration while completing a physically demanding activity. This study included six college-age participants from the University of Texas at El Paso. Anthropometric measurements were taken before the beginning of the study. Afterward, each participant’s basal capillary blood lactate level was established by averaging lactate concentration from three consecutive days. Capillary blood samples were taken from the participant’s earlobe, and lactate concentration (mmol/L) was assessed using the Lactate Plus Lactate Analyzer (Nova Biomedical). After obtaining all the baseline measurements, each participant completed six simulated work sessions, one with sleeves and another without sleeves, at an intensity of 25 Watts, 50 Watts, and 75 Watts a cadence of 60 RPM, and 10 minutes of duration. All participants rested for at least 72 hours between sessions to prevent muscular fatigue effects of lactate concentrations. The use of compression sleeves showed an average reduction of lactate concentration of 0.2 mmol/L. This study shows the potential benefits of wearing compression sleeves while performing activities involving the upper limbs by helping prevent lactate accumulation, a common indicator of muscular effort.
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Habes, Maria, Rachel Salvador, Erica Dijkers, and R. P. Van Steenwijk. "Arterial lactate vs venous lactate as indicator of metabolic limitation during cardiopulmonary exercise testing." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa1408.

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Serganova, Inna, Asif Rizwan, Xiaohui Ni, Sunitha Thakur, Ronald Blasberg, and Jason Koutcher. "Abstract 1003: A link between lactate dehydrogenase A, lactate and tumor phenotype identified by imaging." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1003.

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Sarreal, Ressa, and Gymama Slaughter. "Dual Glucose and Lactate Electrochemical Biosensor." In 2018 IEEE 13th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2018. http://dx.doi.org/10.1109/nems.2018.8556860.

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Huang, Zhihong, Jing Gao, Tiantao Zhao, Weijie Li, Liya Zhou, and Ying He. "Lipase Catalyzed Synthesis of Ethyl Lactate." In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2009). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5163016.

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KITAGAWA, KAORU. "MEASUREMENT OF BLOOD LACTATE DURING SPORTS." In 2008 Access Conference in Sport Science. WORLD SCIENTIFIC, 2010. http://dx.doi.org/10.1142/9789814304092_0006.

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Reports on the topic "Lactate"

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Mosher, Jennifer J., Meghan M. Drake, Susan L. Carroll, Zamin K. Yang, Christopher W. Schadt, Stephen D. Brown, Mircea Podar, et al. Microbial Community Dynamics of Lactate Enriched Hanford Groundwaters. Office of Scientific and Technical Information (OSTI), May 2010. http://dx.doi.org/10.2172/986244.

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Meyer, Birte, and David Stahl. Syntrophic Degradation of Lactate in Methanogenic Co-cultures. Office of Scientific and Technical Information (OSTI), May 2010. http://dx.doi.org/10.2172/986317.

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Ma, Lianjia. Multichannel Simultaneous Determination of Activities of Lactate Dehydrogenase. Office of Scientific and Technical Information (OSTI), September 2000. http://dx.doi.org/10.2172/764689.

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Piper, Robert C. Parasite Lactate Dehydrogenase for Diagnosis of Plasmodium Falciparum. Phase II. Fort Belvoir, VA: Defense Technical Information Center, April 1997. http://dx.doi.org/10.21236/adb230017.

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Kim, Yuan, Edward M. Steadham, Steven M. Lonergan, and Elisabeth J. Huff-Lonergan. Antioxidant Capacity of Calcium Lactate on m-Calpain Activity In Vitro. Ames (Iowa): Iowa State University, January 2009. http://dx.doi.org/10.31274/ans_air-180814-1237.

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Reeves, John T. Beta-Adrenergic Blockade and Lactate Metabolism during Exercise at High Altitude. Fort Belvoir, VA: Defense Technical Information Center, January 1993. http://dx.doi.org/10.21236/ada263544.

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Li, Fenglei. Automated High Throughput Protein Crystallization Screening at Nanoliter Scale and Protein Structural Study on Lactate Dehydrogenase. Office of Scientific and Technical Information (OSTI), August 2006. http://dx.doi.org/10.2172/892735.

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Qian, Chengliang. Structurally Integrated Photoluminescence-Based Lactate Sensor Using Organic Light Emitting Devices (OLEDs) as the Light Source. Office of Scientific and Technical Information (OSTI), January 2006. http://dx.doi.org/10.2172/892736.

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Li, Zhizhuo, Chengxin Li, guangxue Wang, Tengqi Li, Xiaoyu Fan, Xin Xu, Peixu Wang, and Wei Sun. Diagnostic accuracy of synovial fluid D-lactate for periprosthetic joint infection: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2021. http://dx.doi.org/10.37766/inplasy2021.9.0036.

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Thakur, Sunitha B. Noninvasive Detection of Lactate as a Biomarker of Response Using Spectral-Selective Multiple Quantum Editing Sequence (SS-SelMQC). Fort Belvoir, VA: Defense Technical Information Center, May 2010. http://dx.doi.org/10.21236/ada534912.

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