Academic literature on the topic 'Labour contract alteration'
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Journal articles on the topic "Labour contract alteration"
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Бочарников, Дмитрий, and Dmitriy Bocharnikov. "Specifics of Scientific Activity as a Ground of Differentiation of Legal Regulation of Labor Relations of Scientific Workers." Journal of Russian Law 2, no. 2 (January 20, 2014): 101–9. http://dx.doi.org/10.12737/2244.
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The article is dedicated to the detection of the specific features of scientific work which determine the specificity of the legal regulation of the labour relations of scientists and scholars. The author provides a general characteristic of the legal status of the researcher and analyses the exceptions from general rules stipulated by Russian legislation as well as the additional rules for the conclusion, alteration and termination of the labour contract with the said category of workers, their qualifications, working conditions and salaries.
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Al-Shebly, Mashael M., and Mahmoud A. Mansour. "Evaluation of Oxidative Stress and Antioxidant Status in Diabetic and Hypertensive Women during Labor." Oxidative Medicine and Cellular Longevity 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/329743.
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Pregnancy in insulin-dependent diabetes mellitus is associated with a greater incidence of fetal abnormality. Animal studies suggested that increased free-radical production and antioxidant depletion may contribute to this risk. The objective of this work was to evaluate oxidative stress and antioxidant capacity in hypertensive, diabetics, and healthy control women during labor. Simultaneous determination of antioxidant enzymes activities, namely glutathione peroxidase (GSH-Px), glutathione reductase (GSH-red), superoxide dismutase (SOD), total antioxidant, and lipid peroxides measured as thiobarbituric acid-reactive substances (TBARS) levels, were carried out in maternal plasma during labor. Plasma GSH-Px activity was found to be significantly increased as it doubled in hypertensive, and diabetic women when compared with healthy control women (P<0.05). In contrast, plasma SOD activity was significantly decreased in both groups when compared to the control group (P<0.05). No significant differences were detected in GSH-Red activity between diabetic, hypertensive and control groups. Alterations in antioxidant enzyme activities were accompanied by a significant increase in the levels of plasma lipid peroxides in hypertensive and diabetic women during labor. Plasma levels of total antioxidants were significantly increased in diabetic women as compared with the control group. Based on our results, it may be concluded that enhanced generation of oxidative stress causes alteration of antioxidant capacity in diabetic and hypertensive women during labor. Alterations in antioxidant and prooxidant components may result in various complications including peroxidation of vital body molecules which may be regarded as an increased risk factor for pregnant women as well as the fetus.
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Hamblin, Kate A. "Changes to policies for work and retirement in EU15 nations (1995–2005)." International Journal of Ageing and Later Life 5, no. 1 (October 13, 2010): 13–43. http://dx.doi.org/10.3384/ijal.1652-8670.105113.
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’’Active ageing’’ policies have been presented as a potential panacea for the conflict between generations many argue will result from demographic ageing. Indeed, as part of a new intergenerational contract, older individuals (here defined as those aged 50-64) are expected to re-engage with, and remain in, the labour market longer. However, this implies all individuals experience the same policy mix. This study uses micro-level data to address changes to work and retirement policies for older individuals from 1995 to 2005, and the resultant alterations to the degree of choice in terms of labour market participation different sub-groups within this age cohort had. The data demonstrate that the policy shift towards ’’active ageing’’ is not universally applied to all older individuals as some retain the ability to early exit from the labour market. Thus the notion of a single intergenerational contract is overly simplistic and neglects a great deal of intragenerational difference.
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Tezuka, N., M. Ali, K. Chwalisz, and R. E. Garfield. "Changes in transcripts encoding calcium channel subunits of rat myometrium during pregnancy." American Journal of Physiology-Cell Physiology 269, no. 4 (October 1, 1995): C1008—C1017. http://dx.doi.org/10.1152/ajpcell.1995.269.4.c1008.
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Extracellular Ca2+ is normally required for myometrial cells to contract. Ca2+ enters muscle cells mainly through voltage-dependent Ca2+ channels (VDCCs) that open in response to action potentials. The synthesis of myometrial VDCCs may change during pregnancy to alter excitation-contraction coupling. We investigated the mRNA levels for the alpha 1- and beta-subunits of the L-type VDCC in rat myometrium to determine whether alterations are associated with term or preterm labor. RNA isolated from myometrial tissues was analyzed by reverse transcription-polymerase chain reaction (PCR) using specific primers designed according to the published sequences of the VDCC subunits. From pregnant rat myometrium, two distinct PCR products were obtained for the alpha 1-subunit: one of the expected size at 372 bp and a smaller at 339 bp. Sequence analysis of the larger product revealed a 99.5 or 88% sequence homology between rat myometrium and rat aorta or rabbit heart, respectively, and the smaller product had an identical sequence to a 33-bp deletion. The two alpha 1-products followed the same trend throughout pregnancy. VDCC alpha 1-mRNA levels increased gradually to 6.9-fold just before labor on day 22 but decreased during labor. However, the beta-subunit mRNA level increased sharply on day 22 and then also declined during labor. Progesterone treatment from day 19 to day 22 inhibited term delivery and prevented the significant increase in alpha 1-mRNA levels. In contrast, antiprogesterone (onapristone, ZK-98.299) treatment on day 17 caused a statistically significant increase in the alpha 1- and beta-VDCC subunit mRNA after 8 and 15 h, respectively, then a decrease during preterm labor at 24 h. We conclude that mRNA levels for the VDCC subunits increase before term and preterm labor but decline during periods when VDCCs are likely at their peaks. The increase in levels of mRNA for VDCC likely reflects changes in expression of VDCCs during periods of term and preterm labor that may facilitate uterine contractility required for this process. Progesterone withdrawal or blockade appears to be responsible for regulating levels of mRNA for VDCC in the myometrium in preparation for labor.
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Sheldon, Rachel E., Chipo Mashayamombe, Shao-Qing Shi, Robert E. Garfield, Anatoly Shmygol, Andrew M. Blanks, and Hugo A. van den Berg. "Alterations in gap junction connexin43/connexin45 ratio mediate a transition from quiescence to excitation in a mathematical model of the myometrium." Journal of The Royal Society Interface 11, no. 101 (December 6, 2014): 20140726. http://dx.doi.org/10.1098/rsif.2014.0726.
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The smooth muscle cells of the uterus contract in unison during delivery. These cells achieve coordinated activity via electrical connections called gap junctions which consist of aggregated connexin proteins such as connexin43 and connexin45. The density of gap junctions governs the excitability of the myometrium (among other factors). An increase in gap junction density occurs immediately prior to parturition. We extend a mathematical model of the myometrium by incorporating the voltage-dependence of gap junctions that has been demonstrated in the experimental literature. Two functional subtypes exist, corresponding to systems with predominantly connexin43 and predominantly connexin45, respectively. Our simulation results indicate that the gap junction protein connexin45 acts as a negative modulator of uterine excitability, and hence, activity. A network with a higher proportion of connexin45 relative to connexin43 is unable to excite every cell. Connexin45 has much more rapid gating kinetics than connexin43 which we show limits the maximum duration of a local burst of activity. We propose that this effect regulates the degree of synchronous excitation attained during a contraction. Our results support the hypothesis that as labour approaches, connexin45 is downregulated to allow action potentials to spread more readily through the myometrium.
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Christman, John. "Analyzing Freedom from the Shadows of Slavery." Journal of Global Slavery 2, no. 1-2 (2017): 162–84. http://dx.doi.org/10.1163/2405836x-00201010.
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Philosophical treatments of core value concepts often abstract from the troubled history and fractured present of the societies to which those concepts are meant to apply. In the case of the political tradition of liberal democratic thought, stretching from the social contract theories of the seventeenth and eighteenth centuries up through contemporary writers, the notion of individual freedom or liberty is central. However, often that idea, and the assumption of its foundational value for persons, is specified from the perspective of those who enjoy it rather than those struggling to attain it. Moreover, the social spaces that theories of justice that locate freedom as a central value have continue to bracket out of existence the patterns of enslavement, oppression and domination that mark all social spaces. This article attempts a reappraisal of certain dominant understandings of the idea of freedom in both historical and contemporary philosophical discourse in light of this alteration of perspective. Specifically, the current practices of coercive labor, trafficking, irregular labor migration, and other forms of “marginal” social lives are brought into focus in order to guide this reappraisal. The article argues that if we assess these conditions as modes of unfreedom then we must utilize an account of freedom that diverges significantly from those dominant notions. A sketch of this alternative, positive, conception of freedom is then offered.
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Kusano, Miyako, Kanjana Worarad, Atsushi Fukushima, Ken Kamiya, Yuka Mitani, Yozo Okazaki, Yasuhiro Higashi, et al. "Transcriptomic, Hormonomic and Metabolomic Analyses Highlighted the Common Modules Related to Photosynthesis, Sugar Metabolism and Cell Division in Parthenocarpic Tomato Fruits during Early Fruit Set." Cells 11, no. 9 (April 22, 2022): 1420. http://dx.doi.org/10.3390/cells11091420.
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Parthenocarpy, the pollination-independent fruit set, can raise the productivity of the fruit set even under adverse factors during the reproductive phase. The application of plant hormones stimulates parthenocarpy, but artificial hormones incur extra financial and labour costs to farmers and can induce the formation of deformed fruit. This study examines the performance of parthenocarpic mutants having no transcription factors of SlIAA9 and SlTAP3 and sldella that do not have the protein-coding gene, SlDELLA, in tomato (cv. Micro-Tom). At 0 day after the flowering (DAF) stage and DAFs after pollination, the sliaa9 mutant demonstrated increased pistil development compared to the other two mutants and wild type (WT). In contrast to WT and the other mutants, the sliaa9 mutant with pollination efficiently stimulated the build-up of auxin and GAs after flowering. Alterations in both transcript and metabolite profiles existed for WT with and without pollination, while the three mutants without pollination demonstrated the comparable metabolomic status of pollinated WT. Network analysis showed key modules linked to photosynthesis, sugar metabolism and cell proliferation. Equivalent modules were noticed in the famous parthenocarpic cultivars ‘Severianin’, particularly for emasculated samples. Our discovery indicates that controlling the genes and metabolites proffers future breeding policies for tomatoes.
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Armin, Sabiha, and Kenneth Nugent. "Effects of COVID-19 infection during pregnancy." Southwest Respiratory and Critical Care Chronicles 9, no. 39 (April 19, 2021): 28–34. http://dx.doi.org/10.12746/swrccc.v9i39.851.
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Women develop important changes in their cardiovascular and respiratory systems during pregnancy. They also have important changes in their immune system which are necessary to tolerate foreign fetal tissue. These expected alterations can increase the likelihood of poor outcomes with certain respiratory infections, especially viral infection. There is extensive literature describing COVID-19 in pregnant women, and there is evidence that this virus can infect the placenta, raising implications for maternal-fetal transmission. Women who contract COVID-19 during pregnancy are at increased risk of preterm labor and other perinatal complications when compared to non-pregnant women. Trials on the safety and efficacy of the COVID-19 vaccines during pregnancy are in progress; several reproductive societies have recommended that women who are planning to get pregnant or are pregnant should get vaccination since there are few reports of adverse events in pregnant women who have received vaccines. Healthcare providers will need to address concerns of infertility, the possibility of vertical transmission, and neonatal infection with women regarding timely vaccination against this disease and other necessary precautions.
Keywords: coronavirus, COVID-19, pregnancy, placental pathology, vertical transmission
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Castillo-Ruiz, Alexandra, Morgan Mosley, Andrew J. Jacobs, Yarely C. Hoffiz, and Nancy G. Forger. "Birth delivery mode alters perinatal cell death in the mouse brain." Proceedings of the National Academy of Sciences 115, no. 46 (October 15, 2018): 11826–31. http://dx.doi.org/10.1073/pnas.1811962115.
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Labor and a vaginal delivery trigger changes in peripheral organs that prepare the mammalian fetus to survive ex utero. Surprisingly little attention has been given to whether birth also influences the brain, and to how alterations in birth mode affect neonatal brain development. These are important questions, given the high rates of cesarean section (C-section) delivery worldwide, many of which are elective. We examined the effect of birth mode on neuronal cell death, a widespread developmental process that occurs primarily during the first postnatal week in mice. Timed-pregnant dams were randomly assigned to C-section deliveries that were yoked to vaginal births to carefully match gestation length and circadian time of parturition. Compared with rates of cell death just before birth, vaginally-born offspring had an abrupt, transient decrease in cell death in many brain regions, suggesting that a vaginal delivery is neuroprotective. In contrast, cell death was either unchanged or increased in C-section–born mice. Effects of delivery mode on cell death were greatest for the paraventricular nucleus of the hypothalamus (PVN), which is central to the stress response and brain–immune interactions. The greater cell death in the PVN of C-section–delivered newborns was associated with a reduction in the number of PVN neurons expressing vasopressin at weaning. C-section–delivered mice also showed altered vocalizations in a maternal separation test and greater body mass at weaning. Our results suggest that vaginal birth acutely impacts brain development, and that alterations in birth mode may have lasting consequences.
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Cheng, Z., M. Elmes, SE Kirkup, DR Abayasekara, and DC Wathes. "Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes." Journal of Endocrinology 182, no. 2 (August 1, 2004): 249–56. http://dx.doi.org/10.1677/joe.0.1820249.
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We investigated the effect of n-6 polyunsaturated fatty acids (PUFAs) on prostaglandin (PG) production by the uterus. A mixed population of endometrial cells (epthelium and stroma) from late-gestation ewes were cultured in defined medium containing linoleic acid (LA, 18:2, n-6), gamma-linolenic acid (GLA, 18:3, n-6) or arachidonic acid (AA, 20:4, n-6) in concentrations of 0 (control), 20 or 100 microM. After 45 h in test medium with or without added PUFAs, cells were challenged with control medium (CM), oxytocin (OT, 250 nM), lipopolysaccharide (LPS, 0.1 micro g/ml) or dexamethasone (DEX, 5 microM) for 22 h in the continued presence of the same concentration of PUFA and the medium was collected for measurement of PGF(2alpha) and PGE(2). Supplementation with LA inhibited the production of PGF(2alpha) but did not alter PGE(2), whereas GLA and AA increased production of both PGs. All PUFA supplements thus increased the ratio of PGE(2) to PGF(2alpha) (E:F ratio) two- to threefold. In control cells, OT and LPS challenges stimulated the production of PGF(2alpha) and PGE(2). In all challenge groups, the concentrations of PGF(2alpha) in response to PUFAs followed the same pattern - LA<control<;GLA<AA - but there were significant alterations in responsiveness as a result of PUFA treatment. In the cells supplemented with 100 microM AA, there was no further increase in PGF(2alpha) output in the presence of OT or LPS and when 100 microM GLA was present neither LPS nor OT stimulated PGE(2) significantly. When LPS was given to AA-supplemented cells, the E:F ratio was increased. DEX did not change PGE(2) production in control or LA-treated cells, but the cells produced significantly less PGF(2alpha), so the E:F ratio was increased. In contrast, in GLA- and AA-treated cells, DEX reduced the production of both PGF(2alpha) and PGE(2), so the E:F ratio was unaltered. In summary, the study showed altered production of PGs in the presence of different PUFAs according to their position in the n-6 metabolic pathway. The type of PUFA present affected responsiveness to OT, LPS and DEX and also changed the ratio of PGE(2) to PGF(2alpha) produced. The possible implications of this work are discussed in relation to the effect of diet on term and pre-term labour, which both require upregulation of the endometrial PG synthetic pathway.
Dissertations / Theses on the topic "Labour contract alteration"
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Tykha, A. P. "Legal Regulation of Amendment of Labour Contract. –." Thesis, Київський національний університет імені Тараса Шевченка, 2017. http://openarchive.nure.ua/handle/document/7670.
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The thesis enabled the resolving of the scientific problem regarding the necessity of the existing theoretical doctrine on the labour contract alterations deepen and adjustment according to the modern needs in consideration of latest changes in the economic and social life of the Ukrainian state. The specifics of labour contract alteration legal regulation under the current and draft labour laws of Ukraine are disclosed. The whole set of problems of labour contract alterations legal regulation is singled out and a number of actual proposals concerning sophistication of the current labour legislation in the appropriate part are formulated. The thesis consists of introduction, 3 sections, divided on 9 sub-sections, conclusions and references. Дисертаційне дослідження дало змогу вирішити наукову проблему, яка полягала у необхідності поглиблення та уточнення існуючого теоретичного вчення про зміни трудового договору відповідно до сучасних потреб з урахуванням останніх змін в економічному та суспільному житті української держави. Розкрито специфіку правового регулювання змін трудового договору за діючим та проектним законодавством України про працю. Виокремлено сукупність проблем правового регулювання змін трудового договору та сформульовано низку актуальних пропозицій щодо вдосконалення чинного законодавства про працю у відповідній частині. Дисертація складається із вступу, трьох розділів, які включають дев’ять підрозділів, висновків, списку використаних джерел.
Books on the topic "Labour contract alteration"
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Mauldin, Erin Stewart. Accelerating Change. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190865177.003.0005.
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Emancipation proved to be a far-reaching ecological event. Whereas the ecological regime of slavery had reinforced extensive land-use practices, the end of slavery weakened them. Freedpeople dedicated less time to erosion control and ditching and used contract negotiations and sharecropping arrangements to avoid working in a centrally directed gang. Understandably, freedpeople preferred to direct their own labor on an individual plot of land. The eventual proliferation of share-based or tenant contracts encouraged the physical reorganization of plantations. The combination of these two progressive alterations to labor relations tragically undermined African Americans’ efforts to achieve economic independence by tightening natural limits on cotton production and reducing blacks’ access to the South’s internal provisioning economy. The cessation, or even reduced frequency, of land maintenance on farms exacerbated erosion, flooding, and crops’ susceptibility to drought.
Book chapters on the topic "Labour contract alteration"
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Carson, Matter. "Epilogue." In A Matter of Moral Justice, 213–24. University of Illinois Press, 2021. http://dx.doi.org/10.5622/illinois/9780252043901.003.0013.
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The epilogue examines the state of the laundry industry in the twenty-first century, arguing that power laundries have not disappeared but rather adapted to the changing needs of the customers. Laundries that had offered family service returned to the industry’s roots by branching out into institutional work and offering new services such as dry cleaning, carpet cleaning, and alterations. In the early 2000s the majority of laundry workers labor for corporations such as Cintas and Aramark, companies that provide and launder linen, uniforms, and other products for hospitals, hotels, restaurants, and other businesses that, in line with neoliberal ideologies and practices, have been outsourcing their work. The epilogue demonstrates that the industry continues to rely on low-wage female and racialized labor, including significant numbers of Latinx workers, some of whom are undocumented. The epilogue briefly discusses a recent campaign led by workers and UNITE HERE to organize laundry workers at Cintas, the nation’s largest uniform rental provider and launderer. The chapter argues that the campaign did not lead to unionization--in contrast to the 1930s--because of fears of employer retaliation as a result of capital’s increasingly sophisticated antiunion tactics and the evisceration of labor law protections; because of feelings of “do-nothing unionism” among workers disenchanted with what they see as a bureaucratic, top-heavy, and sometimes ineffective labor movement; and finally because of fears of job loss and deportation. The final section discusses what laundry workers today can learn from the laundry workers in this book who organized in the 1930s and subsequently led a militant battle for economic dignity and racial justice.
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Tribe, Keith. "The Scientisation of Economics." In Constructing Economic Science, 333–68. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780190491741.003.0012.
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Lionel Robbins was appointed head of the Department of Economics at the London School of Economics (LSE) in 1929 following the sudden death of Allyn Young, the incumbent professor. Young had not made any significant alteration to the teaching at LSE, but from the very first Robbins set about reorganising the profile of economics teaching. The framework within which he did this was one of a ‘science’ based upon ‘economic principles’, and in 1932 his Essay on the Nature and Significance of Economic Science provided the methodological template for his project. This work appears to owe a great deal to Austrian economics, but it can be demonstrated that this was indirect, chiefly through the work of Wicksteed and Wicksell, hence reflecting economics where it had stood in the 1880s. Nonetheless, Robbins was successful in repackaging this work, and his Essay stimulated the development of discussions of economic method. In addition, Robbins’s lectures provided the template for the textbook literature of the 1950s, cementing the influence of the LSE on the training of young economists. However, this training remained at the undergraduate level for the most part due to the lack of labour market demand for economists in Britain; in the United States, by contrast, graduate teaching became the motor through which American economics came to dominate the international teaching of economics.