Journal articles on the topic 'KIT tyrosine kinase'
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Heinrich, Michael C., Diana J. Griffith, Brian J. Druker, Cecily L. Wait, Kristen A. Ott, and Amy J. Zigler. "Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor." Blood 96, no. 3 (August 1, 2000): 925–32. http://dx.doi.org/10.1182/blood.v96.3.925.
Full textHeinrich, Michael C., Diana J. Griffith, Brian J. Druker, Cecily L. Wait, Kristen A. Ott, and Amy J. Zigler. "Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor." Blood 96, no. 3 (August 1, 2000): 925–32. http://dx.doi.org/10.1182/blood.v96.3.925.015k50_925_932.
Full textLedoux, Julie, and Luba Tchertanov. "Does Generic Cyclic Kinase Insert Domain of Receptor Tyrosine Kinase KIT Clone Its Native Homologue?" International Journal of Molecular Sciences 23, no. 21 (October 25, 2022): 12898. http://dx.doi.org/10.3390/ijms232112898.
Full textMarmigère, Frédéric, Frédérique Scamps, and Jean Valmier. "Le récepteur tyrosine kinase c-Kit." médecine/sciences 24, no. 5 (May 2008): 464–66. http://dx.doi.org/10.1051/medsci/2008245464.
Full textBandi, Srinivasa Rao, Christian Brandts, Marion Rensinghoff, Rebekka Grundler, Lara Tickenbrock, Gabriele Köhler, Justus Duyster, et al. "E3 ligase–defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease." Blood 114, no. 19 (November 5, 2009): 4197–208. http://dx.doi.org/10.1182/blood-2008-12-190934.
Full textKinashi, T., JA Escobedo, LT Williams, K. Takatsu, and TA Springer. "Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-gamma 1 pathways." Blood 86, no. 6 (September 15, 1995): 2086–90. http://dx.doi.org/10.1182/blood.v86.6.2086.bloodjournal8662086.
Full textSun, Jianmin, Malin Pedersen, and Lars Rönnstrand. "The D816V Mutation of C-Kit Circumvents a Requirement for Src Family Kinases in C-Kit Mediated Signal Tranduction and Transformation." Blood 112, no. 11 (November 16, 2008): 2849. http://dx.doi.org/10.1182/blood.v112.11.2849.2849.
Full textPan, Jingxuan, Hagop Kantarjian, Jorge Cortes, Francis Giles, and Srdan Verstovsek. "Effect of Tyrosine Kinase Inhibitor INNO-406 on Human Mast Cells Bearing Mutated c-KIT Tyrosine Kinase." Blood 108, no. 11 (November 16, 2006): 4890. http://dx.doi.org/10.1182/blood.v108.11.4890.4890.
Full textKornbluth, S., K. E. Paulson, and H. Hanafusa. "Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries." Molecular and Cellular Biology 8, no. 12 (December 1988): 5541–44. http://dx.doi.org/10.1128/mcb.8.12.5541-5544.1988.
Full textKornbluth, S., K. E. Paulson, and H. Hanafusa. "Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries." Molecular and Cellular Biology 8, no. 12 (December 1988): 5541–44. http://dx.doi.org/10.1128/mcb.8.12.5541.
Full textMasson, Kristina, Elke Heiss, Hamid Band, and Lars Rönnstrand. "Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation." Biochemical Journal 399, no. 1 (September 13, 2006): 59–67. http://dx.doi.org/10.1042/bj20060464.
Full textMasson, Kristina, Elke Heiss, and Lars Ronnstrand. "Negative Regulation of c-Kit Is Dependent on Direct Binding of Cbl to Tyrosines 568 and 936." Blood 106, no. 11 (November 16, 2005): 2288. http://dx.doi.org/10.1182/blood.v106.11.2288.2288.
Full textDeBERRY, Candy, Sherry MOU, and Diana LINNEKIN. "Stat1 associates with c-kit and is activated in response to stem cell factor." Biochemical Journal 327, no. 1 (October 1, 1997): 73–80. http://dx.doi.org/10.1042/bj3270073.
Full textKoltai, Zsófia, Bernadett Szabó, Judit Jakus, and Péter Vajdovich. "Tyrosine kinase expression analyses in canine mammary gland tumours – A pilot study." Acta Veterinaria Hungarica 66, no. 2 (June 2018): 294–308. http://dx.doi.org/10.1556/004.2018.027.
Full textRottapel, R., M. Reedijk, D. E. Williams, S. D. Lyman, D. M. Anderson, T. Pawson, and A. Bernstein. "The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor." Molecular and Cellular Biology 11, no. 6 (June 1991): 3043–51. http://dx.doi.org/10.1128/mcb.11.6.3043-3051.1991.
Full textRottapel, R., M. Reedijk, D. E. Williams, S. D. Lyman, D. M. Anderson, T. Pawson, and A. Bernstein. "The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor." Molecular and Cellular Biology 11, no. 6 (June 1991): 3043–51. http://dx.doi.org/10.1128/mcb.11.6.3043.
Full textTsujimura, T., T. Furitsu, M. Morimoto, K. Isozaki, S. Nomura, Y. Matsuzawa, Y. Kitamura, and Y. Kanakura. "Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation." Blood 83, no. 9 (May 1, 1994): 2619–26. http://dx.doi.org/10.1182/blood.v83.9.2619.2619.
Full textTsujimura, T., T. Furitsu, M. Morimoto, K. Isozaki, S. Nomura, Y. Matsuzawa, Y. Kitamura, and Y. Kanakura. "Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation." Blood 83, no. 9 (May 1, 1994): 2619–26. http://dx.doi.org/10.1182/blood.v83.9.2619.bloodjournal8392619.
Full textBarnett, Christine M., and Michael C. Heinrich. "Management of Tyrosine Kinase Inhibitor–Resistant Gastrointestinal Stromal Tumors." American Society of Clinical Oncology Educational Book, no. 32 (June 2012): 663–68. http://dx.doi.org/10.14694/edbook_am.2012.32.66.
Full textChan, Perry M., Subburaj Ilangumaran, Jose La Rose, Avijit Chakrabartty, and Robert Rottapel. "Autoinhibition of the Kit Receptor Tyrosine Kinase by the Cytosolic Juxtamembrane Region." Molecular and Cellular Biology 23, no. 9 (May 1, 2003): 3067–78. http://dx.doi.org/10.1128/mcb.23.9.3067-3078.2003.
Full textAnzai, Naoyuki, Younghee Lee, Byung-S. Youn, Seiji Fukuda, Young-June Kim, Charlie Mantel, Makoto Akashi, and Hal E. Broxmeyer. "c-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors." Blood 99, no. 12 (June 15, 2002): 4413–21. http://dx.doi.org/10.1182/blood.v99.12.4413.
Full textTang, B., H. Mano, T. Yi, and J. N. Ihle. "Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding." Molecular and Cellular Biology 14, no. 12 (December 1994): 8432–37. http://dx.doi.org/10.1128/mcb.14.12.8432-8437.1994.
Full textTang, B., H. Mano, T. Yi, and J. N. Ihle. "Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding." Molecular and Cellular Biology 14, no. 12 (December 1994): 8432–37. http://dx.doi.org/10.1128/mcb.14.12.8432.
Full textGalanis, A., and M. Levis. "Inhibition of c-Kit by tyrosine kinase inhibitors." Haematologica 100, no. 3 (November 25, 2014): e77-e79. http://dx.doi.org/10.3324/haematol.2014.117028.
Full textTaniguchi, Yoshitaka, Roanna London, Karin Schinkmann, Shuxian Jiang, and Hava Avraham. "The Receptor Protein Tyrosine Phosphatase, PTP-RO, Is Upregulated During Megakaryocyte Differentiation and Is Associated With the c-Kit Receptor." Blood 94, no. 2 (July 15, 1999): 539–49. http://dx.doi.org/10.1182/blood.v94.2.539.
Full textTaniguchi, Yoshitaka, Roanna London, Karin Schinkmann, Shuxian Jiang, and Hava Avraham. "The Receptor Protein Tyrosine Phosphatase, PTP-RO, Is Upregulated During Megakaryocyte Differentiation and Is Associated With the c-Kit Receptor." Blood 94, no. 2 (July 15, 1999): 539–49. http://dx.doi.org/10.1182/blood.v94.2.539.414k40_539_549.
Full textShi, Xiarong, Leiliane P. Sousa, Elizabeth M. Mandel-Bausch, Francisco Tome, Andrey V. Reshetnyak, Yaron Hadari, Joseph Schlessinger, and Irit Lax. "Distinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibition." Proceedings of the National Academy of Sciences 113, no. 33 (August 1, 2016): E4784—E4793. http://dx.doi.org/10.1073/pnas.1610179113.
Full textDastych, Jaroslaw, Dennis Taub, Mary C. Hardison, and Dean D. Metcalfe. "Tyrosine kinase-deficient Wvc-kit induces mast cell adhesion and chemotaxis." American Journal of Physiology-Cell Physiology 275, no. 5 (November 1, 1998): C1291—C1299. http://dx.doi.org/10.1152/ajpcell.1998.275.5.c1291.
Full textHeinrich, Michael C., Charles D. Blanke, Brian J. Druker, and Christopher L. Corless. "Inhibition of KIT Tyrosine Kinase Activity: A Novel Molecular Approach to the Treatment of KIT-Positive Malignancies." Journal of Clinical Oncology 20, no. 6 (March 15, 2002): 1692–703. http://dx.doi.org/10.1200/jco.2002.20.6.1692.
Full textRoberts, Riyaadh, and Dhirendra Govender. "Gene of the month: KIT." Journal of Clinical Pathology 68, no. 9 (July 1, 2015): 671–74. http://dx.doi.org/10.1136/jclinpath-2015-203207.
Full textIqbal, Nida, and Naveed Iqbal. "Imatinib: A Breakthrough of Targeted Therapy in Cancer." Chemotherapy Research and Practice 2014 (May 19, 2014): 1–9. http://dx.doi.org/10.1155/2014/357027.
Full textMiyazawa, K., DA Williams, A. Gotoh, J. Nishimaki, HE Broxmeyer, and K. Toyama. "Membrane-bound Steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form." Blood 85, no. 3 (February 1, 1995): 641–49. http://dx.doi.org/10.1182/blood.v85.3.641.bloodjournal853641.
Full textVoisset, Edwige, Sophie Lopez, Patrice Dubreuil, and Paulo De Sepulveda. "The tyrosine kinase FES is an essential effector of KITD816V proliferation signal." Blood 110, no. 7 (October 1, 2007): 2593–99. http://dx.doi.org/10.1182/blood-2007-02-076471.
Full textSamayawardhena, Lionel, and Andrew W. B. Craig. "Involvement of Fps/Fes and Fer Kinases in c-Kit Signalling in Mast Cells and Mast Cell Leukemias." Blood 106, no. 11 (November 16, 2005): 3887. http://dx.doi.org/10.1182/blood.v106.11.3887.3887.
Full textLoriaux, Marc, Ross Levine, Jeffrey Tyner, Stephan Frohling, Claudia Scholl, Eric Stoffregen, Gerlinde Wernig, et al. "High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia." Blood 110, no. 11 (November 16, 2007): 886. http://dx.doi.org/10.1182/blood.v110.11.886.886.
Full textLAM, Lily P. Y., Rowena Y. K. CHOW, and Stuart A. BERGER. "A transforming mutation enhances the activity of the c-Kit soluble tyrosine kinase domain." Biochemical Journal 338, no. 1 (February 8, 1999): 131–38. http://dx.doi.org/10.1042/bj3380131.
Full textZeng, Shan, Zhiheng Xu, Stan Lipkowitz, and Jack B. Longley. "Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl)." Blood 105, no. 1 (January 1, 2005): 226–32. http://dx.doi.org/10.1182/blood-2004-05-1768.
Full textReboll, Marc R., Stefanie Klede, Manuel H. Taft, Chen-Leng Cai, Loren J. Field, Kory J. Lavine, Andrew L. Koenig, et al. "Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase." Science 376, no. 6599 (June 17, 2022): 1343–47. http://dx.doi.org/10.1126/science.abn3027.
Full textHirata, T., E. Morii, M. Morimoto, T. Kasugai, T. Tsujimura, S. Hirota, Y. Kanakura, S. Nomura, and Y. Kitamura. "Stem cell factor induces outgrowth of c-kit-positive neurites and supports the survival of c-kit-positive neurons in dorsal root ganglia of mouse embryos." Development 119, no. 1 (September 1, 1993): 49–56. http://dx.doi.org/10.1242/dev.119.1.49.
Full textFawzy, Ahmed, Samira Mahmoud Abd Allah, Mostafa Mohammed Salem, and Lobna Omar Al Farouk. "Immunohistochemical and Histopathological Study of Anaplastic Lymphoma Kinase and Tyrosine-kinase Receptor Expression in Bronchogenic Carcinoma." Open Access Macedonian Journal of Medical Sciences 9, A (February 18, 2021): 106–13. http://dx.doi.org/10.3889/oamjms.2021.5671.
Full textFunasaka, Y., T. Boulton, M. Cobb, Y. Yarden, B. Fan, S. D. Lyman, D. E. Williams, D. M. Anderson, R. Zakut, and Y. Mishima. "c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas." Molecular Biology of the Cell 3, no. 2 (February 1992): 197–209. http://dx.doi.org/10.1091/mbc.3.2.197.
Full textKlug, Lillian Rose, Jeffrey Tyner, and Michael C. Heinrich. "LMTK3 as a novel regulator of oncogenic KIT in KIT-mutant cancers." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 11044. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.11044.
Full textTyner, Jeffrey W., Denise K. Walters, Stephanie G. Willis, Mary Luttropp, Jason Oost, Marc Loriaux, Heidi Erickson, et al. "RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia." Blood 111, no. 4 (February 15, 2008): 2238–45. http://dx.doi.org/10.1182/blood-2007-06-097253.
Full textDhillon, Sohita. "Ripretinib: First Approval." Drugs 80, no. 11 (June 23, 2020): 1133–38. http://dx.doi.org/10.1007/s40265-020-01348-2.
Full textGrowney, Joseph D., Jennifer J. Clark, Jennifer Adelsperger, Richard Stone, Doriano Fabbro, James D. Griffin, and D. Gary Gilliland. "Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412." Blood 106, no. 2 (July 15, 2005): 721–24. http://dx.doi.org/10.1182/blood-2004-12-4617.
Full textTaylor, Marcia L., Jaroslaw Dastych, Devinder Sehgal, Magnus Sundstrom, Gunnar Nilsson, Cem Akin, Rose G. Mage, and Dean D. Metcalfe. "The Kit-activating mutation D816V enhances stem cell factor–dependent chemotaxis." Blood 98, no. 4 (August 15, 2001): 1195–99. http://dx.doi.org/10.1182/blood.v98.4.1195.
Full textMcGlade, C. J., C. Ellis, M. Reedijk, D. Anderson, G. Mbamalu, A. D. Reith, G. Panayotou, P. End, A. Bernstein, and A. Kazlauskas. "SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors." Molecular and Cellular Biology 12, no. 3 (March 1992): 991–97. http://dx.doi.org/10.1128/mcb.12.3.991-997.1992.
Full textMcGlade, C. J., C. Ellis, M. Reedijk, D. Anderson, G. Mbamalu, A. D. Reith, G. Panayotou, P. End, A. Bernstein, and A. Kazlauskas. "SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors." Molecular and Cellular Biology 12, no. 3 (March 1992): 991–97. http://dx.doi.org/10.1128/mcb.12.3.991.
Full textEdling, Charlotte E., and Bengt Hallberg. "c-Kit—A hematopoietic cell essential receptor tyrosine kinase." International Journal of Biochemistry & Cell Biology 39, no. 11 (January 2007): 1995–98. http://dx.doi.org/10.1016/j.biocel.2006.12.005.
Full textVerstovsek, Srdan, Cem Akin, Giles J. Francis, Manshouri Taghi, Ly Huynh, Paul W. Manley, Leila Alland, Margaret Dugan, Jorge E. Cortes, and Kantarjian M. Hagop. "Effects of AMN107, a Novel Aminopyrimidine Tyrosine Kinase Inhibitor, on Human Mast Cells Bearing Wild-Type or Mutated Codon 816 c-kit." Blood 106, no. 11 (November 16, 2005): 3528. http://dx.doi.org/10.1182/blood.v106.11.3528.3528.
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