Relevant bibliographies by topics / Kinogid / Journal articles

Journal articles on the topic 'Kinogid'

To see the other types of publications on this topic, follow the link: Kinogid.
Author: Grafiati
Published: 30 May 2022
Last updated: 31 May 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Kinogid.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Ritsou, E., H. Le Buanec, F. Haghighi Rad, P. Larcier, D. Zagury, and G. Uzan. "VEGF kinoid vaccine, a therapeutic arm against tumor angiogenesis and metastases." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 3018. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.3018.

Full text
Abstract:
3018 Background: Vascular endothelial growth factor (VEGF) plays a central role in neoangiogenesis and thus represents an important therapeutic target in antiangiogenic cancer therapy strategies. We have developed an anti-VEGF vaccine VEGF kinoid that elicits high titres of neutralizing anti-VEGF antibodies in mice. In this study we have evaluated the immunogenicity, safety and efficacy of VEGF kinoid in preventing tumor growth and metastases in mice. Methods: The efficacy of VEGF kinoid was evaluated in a model of active immunization (CT26 colon carcicoma lung metastases model) and in two models of passive immunization. On the passive immunization setting two VEGF secreting xenograft tumor models, A673 rhabdomyosarcoma and HT29 colon carcinoma, were used to evaluate the ability of IgGs derived from kinoid immunized mice to inhibit tumor growth in comparison with bevacizumab. Results: Active immunization with autologous VEGF Kinoid (mVEGF kinoid) triggered a strong anti-VEGF antibody but no cellular immune response in mice. The anti-VEGF Abs exhibited high neutralizing capacity as assessed via inhibition of human umbilical vein endothelial cell proliferation in the presence of VEGF and binding to the Flk-1 receptor. In mVEGF kinoid immunized BALB/c mice challenged with syngeneic CT26 colorectal tumor cells the lung metastases were inhibited. In human VEGF (hVEGF) kinoid immunized Balb/c mice neutralizing anti-hVEGF Abs were elicited. Purified IgG from these mice inhibited tumor growth of human A673 rhabdomyosarcoma and HT29 colon carcinoma cells xenografted in Swiss nude and NOD/SCID mice respectively as assessed by T/C% measurements. Tumor cell growth inhibition was similar to that in mice receiving therapeutic doses of bevacizumab. Active immunization against VEGF showed an excellent safety profile in mice and no impairment of would healing processes was observed after surgical interventions in immunized mice. Conclusions: These experiments show that active immunization with VEGF kinoid elicits polyclonal neutralizing anti-VEGF Abs that inhibit metastases and tumor growth in mice. It may thus represent an alternative strategy to safely combat VEGF-dependent neovascularization and metastases occurring in malignant tumors. No significant financial relationships to disclose.
APA, Harvard, Vancouver, ISO, and other styles
2

Romankiewicz, Tanja, Richard Bradley, Amanda Clarke, Jamie Quartermaine, Irvine Ross, Veronica Ross, Derek Hamilton, and Rick Schulting. "Old Kinord, Aberdeenshire." Proceedings of the Society of Antiquaries of Scotland 149 (November 16, 2020): 221–47. http://dx.doi.org/10.9750/psas.149.1293.

Full text
Abstract:
The paper reports on research at two well-preserved Iron Age settlement sites in north-east Scotland, occupied between the 2nd century BC and 2nd century AD. At Old Kinord, trenches first excavated in 1903 were reopened, shedding new light on the chronology and structural history of a pair of stone roundhouses and two souterrains. The project extended to new surveys of this site and its neighbour at New Kinord. It investigated the character of the unusually large stone structures found there and the ways in which they were built and used. This report also considers the character of the original excavation, which was conducted by the future Lord Abercromby, a significant figure in the history of Scottish archaeology. Canmore ID 17072 Canmore ID 17065 Canmore ID 33981 Canmore ID 16972 Canmore ID 17057 Canmore ID 33980
APA, Harvard, Vancouver, ISO, and other styles
3

Ökten, Salih. "Kinolin temelli yeni antikanser ajanlar." Academic Perspective Procedia 2, no. 3 (November 22, 2019): 538–43. http://dx.doi.org/10.33793/acperpro.02.03.46.

Full text
Abstract:
Kinolin çekirdeği, geniş bir spektrumda biyolojik aktivite sergileyen birçok doğal ve farmakolojik açıdan aktif bileşiğin ana iskeletini oluşturur. Sübstitüe edilmiş siyano kinolin bileşikleri, büyüme faktörü reseptörü protein tirozin kinaz aktivitesini inhibe edebilmektedir. Farklı gruplara sahip ajanlar ayrıca biyolojik sistemler arasında bağlanan küçük molekül inhibitörleri olarak da işlev görür. Son zamanlarda, sübstitüe edilmiş veya sübstitüe edilmemiş 1,2,3,4-tetrahidrokinolinin bromlama reaksiyonu temelli 6-bromo-, 6,8-dibromo- ve 3,6,8-tribromokinolinlerin sentezi için yeni bir sentetik stratejiler keşfettik. Metal-brom değişimi reaksiyonlarıyla bromlu kinolinlerden 6,8-disübstitüe edilmiş kinolin türevlerinin uygun sentez yollarını ve bromlu ürünlerin disübstitüe kinolinler için öncü bileşikler olduğu rapor edildi. Bu çalışmaların akabinde, 6,8-dibromokinolin, kenetleme ve yer değiştirme reaksiyonları ile fenil, siyano, metoksi ve hidroksi türevlerine dönüştürüldü. Bu strateji ile sentezlenen kinolin türevleri, spesifik antikanser aktiviteleri gösterdi. Yapı aktivite çalışmalarına uygun olarak, fenil, siyano, nitro, metoksi gruplarına sahip kinolin türevlerinin kolon, servikal, akciğer, göğüs kanser hücre hatlarına karşı etkili bir inhibisyon gösterdiği tespit edilmiştir.
APA, Harvard, Vancouver, ISO, and other styles
4

Anshari, Irham Nur. "Sistem Klasifi kasi dalam Pemutaran Film: Studi Kasus Klasifi kasi Film di Kinoki." Jurnal Ilmu Sosial dan Ilmu Politik 17, no. 3 (September 21, 2016): 220. http://dx.doi.org/10.22146/jsp.13087.

Full text
Abstract:
This article concerns with the background, implementation, public acceptance and evaluation of theapplication of classification system as film regulation by Kinoki, an alternative screening space inYogyakarta (2005-2011). The research adopted in this article is case studies. From the studies it is seenthat the implementation of classifi cation system at Kinoki is an eff ort to protect fi lm viewers, while theapplication itself is more as a guideline for the viewers, yet so far public awareness and acceptance to thissystem is limited.
APA, Harvard, Vancouver, ISO, and other styles
5

Miliaras, Nicholas. "Survey Kinase Activity from Kinomic Heights." Genetic Engineering & Biotechnology News 34, no. 10 (May 15, 2014): 12, 14–15. http://dx.doi.org/10.1089/gen.34.10.07.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

ABITBOL, B., A. PROVOST, G. GROUART-VOGEL, S. BERNIER, E. ADAM-BUCZKOWSKI, D. ZAGURY, and M. ABITBOL. "Encouraging results of a VEGF kinoid against experimental choroidal neovascularization." Acta Ophthalmologica 87 (September 2009): 0. http://dx.doi.org/10.1111/j.1755-3768.2009.4352.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Semerano, Luca, Eric Assier, Laure Delavallée, and Marie-Christophe Boissier. "Kinoid of human tumor necrosis factor-alpha for rheumatoid arthritis." Expert Opinion on Biological Therapy 11, no. 4 (March 9, 2011): 545–50. http://dx.doi.org/10.1517/14712598.2011.566856.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Rurangwa, Edouard, Bernard Vanlauwe, and Ken E. Giller. "The response of climbing bean to fertilizer and organic manure in the Northern Province of Rwanda." Experimental Agriculture 56, no. 5 (October 2020): 722–37. http://dx.doi.org/10.1017/s0014479720000277.

Full text
Abstract:
AbstractClimbing beans play a central role in food security of rural households in the densely populated highlands of East and Central Africa. Soil fertility degradation and the lack of nutrient inputs are major limitations to yield of beans and other crops. We conducted field trials in Northern Rwanda in Kinoni and Muko villages to evaluate the effect of mineral N, P, and K fertilizers (both alone and in combination) and farmyard manure on nitrogen fixation and grain yields of climbing bean in smallholder farmers’ fields. The trials were laid down in a randomized complete block design with seven replicate blocks in each village. Manure and fertilizer application led to greater yields in all fields, and the largest yields were achieved when manure was combined with NPK. Large variability in yield between fields was observed. Application of fertilizer together with manure increased the grain yield from 1.5 to 3.9 t ha−1 in Kinoni and from 2.6 to 5.4 t ha−1 in Muko. Fertilizer and/or manure increased stover yield from 0.8 to 2.3 t ha−1 in Kinoni and from 1.5 to 3.4 t ha−1 in Muko. Application of 30 kg P ha−1 and 5 t manure ha−1 led to increased N and P uptake (from 49 to 106 kg N ha−1 and from 6.1 to 12.4 kg P ha−1 in Kinoni and from 46 to 128 kg N ha−1 and from 5.3 to 17.9 kg P ha−1 in Muko). There was no clear relationship between soil fertility characteristics and the response of climbing bean to applied inputs at Muko site. However, at Kinoni site, limited response to manure and NPK application was observed in plots where soil available P and soil exchangeable K were relatively low. Our results show the benefits of using manure along with mineral fertilizers for increased climbing bean yields and nutrient uptake in smallholder farming systems.
APA, Harvard, Vancouver, ISO, and other styles
9

Määttänen, Pekka, Brett Trost, Erin Scruten, Andrew Potter, Anthony Kusalik, Philip Griebel, and Scott Napper. "Divergent Immune Responses to Mycobacterium avium subsp. paratuberculosis Infection Correlate with Kinome Responses at the Site of Intestinal Infection." Infection and Immunity 81, no. 8 (May 28, 2013): 2861–72. http://dx.doi.org/10.1128/iai.00339-13.

Full text
Abstract:
ABSTRACTMycobacterium aviumsubsp.paratuberculosisis the causative agent of Johne's disease (JD) in cattle.M. aviumsubsp.paratuberculosisinfects the gastrointestinal tract of calves, localizing and persisting primarily in the distal ileum. A high percentage of cattle exposed toM. aviumsubsp.paratuberculosisdo not develop JD, but the mechanisms by which they resist infection are not understood. Here, we merge an establishedin vivobovine intestinal segment model forM. aviumsubsp.paratuberculosisinfection with bovine-specific peptide kinome arrays as a first step to understanding how infection influences host kinomic responses at the site of infection. Application of peptide arrays toin vivotissue samples represents a critical and ambitious step in using this technology to understand host-pathogen interactions. Kinome analysis was performed on intestinal samples from 4 ileal segments subdivided into 10 separate compartments (6M. aviumsubsp.paratuberculosis-infected compartments and 4 intra-animal controls) using bovine-specific peptide arrays. Kinome data sets clustered into two groups, suggesting unique binary responses toM. aviumsubsp.paratuberculosis. Similarly, twoM. aviumsubsp.paratuberculosis-specific immune responses, characterized by different antibody, T cell proliferation, and gamma interferon (IFN-γ) responses, were also observed. Interestingly, the kinomic groupings segregated with the immune response groupings. Pathway and gene ontology analyses revealed that differences in innate immune and interleukin signaling and particular differences in the Wnt/β-catenin pathway distinguished the kinomic groupings. Collectively, kinome analysis of tissue samples offers insight into the complex cellular responses induced byM. aviumsubsp.paratuberculosisin the ileum and provides a novel method to understand mechanisms that alter the balance between cell-mediated and antibody responses toM. aviumsubsp.paratuberculosisinfection.
APA, Harvard, Vancouver, ISO, and other styles
10

Noé, Gaëlle, Audrey Bellesoeur, Lisa Golmard, Audrey Thomas-Schoemann, Pascaline Boudou-Rouquette, Manuela Tiako Meyo, Alicja Puszkiel, et al. "Differential Kinase Activation in Peripheral Blood Mononuclear Cells from Non-Small-Cell Lung Cancer Patients Treated with Nivolumab." Cancers 11, no. 6 (May 31, 2019): 762. http://dx.doi.org/10.3390/cancers11060762.

Full text
Abstract:
In the era of precision medicine, research of biomarkers for identification of responders to nivolumab therapy is a major challenge. Peripheral blood mononuclear cells (PBMC) could be an interesting surrogate tissue for identifying pharmacodynamic biomarkers. The aim of this exploratory study was to investigate the global serine/threonine kinase (STK) activity in PBMC from non-small-cell lung cancer (NSCLC) patients using a high throughput kinomic profiling method. PamChip® microarrays were used to explore the STK kinomic profile in PBMC from 28 NSCLC patients before nivolumab initiation (D0) and on day 14 (D14) of the first administration. Two clusters of patients (A and B) were identified at D0, median overall survival (OS) tended to be longer in cluster A than in B (402 vs. 112.5 days, respectively; p = 0.15). Interestingly, the PD-L1 tumor cell score (p = 0.045), the count of CD8+ cells (p = 0.023) and the total body weight (p = 0.038) were statistically different between the clusters. On D14, clusters C and D were identified. Greater activity of most STK, especially those of the PI3K/Akt signaling pathway, was noticed among cluster C. No significant difference between C and D was observed regarding OS. Considering the small number of patients, results from this preliminary study are not conclusive. However, the 4-fold longer median OS in cluster A paves the way to further investigate, in a larger cohort of NSCLC patients, the benefit of basal STK kinomic profile in PBMC to identify responders to nivolumab therapy.
APA, Harvard, Vancouver, ISO, and other styles
11

Rad, F. H., H. Le Buanec, S. Paturance, P. Larcier, P. Genne, B. Ryffel, A. Bensussan, et al. "VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases." Proceedings of the National Academy of Sciences 104, no. 8 (February 14, 2007): 2837–42. http://dx.doi.org/10.1073/pnas.0611022104.

Full text
APA, Harvard, Vancouver, ISO, and other styles
12

DUAN, YANI, YATING ZHANG, and CHRISTOPHER H. DIETRICH. "Six new species of Stenometopiini (Hemiptera: Cicadellidae: Deltocephalinae) with redescription of additional species and new distributional records." Zootaxa 4603, no. 2 (May 9, 2019): 201. http://dx.doi.org/10.11646/zootaxa.4603.2.1.

Full text
Abstract:
Six new species of Stenometopiini are described: Stirellus paracatalinus sp. nov. from Mexico, Stirellus lesioensis sp. nov. from Republic of Congo, Stirellus paralesioensis sp. nov. from South Africa, Stirellus kitwensis sp. nov. from Zambia, Stirellus madagascarensis sp. nov. from Madagascar, and Stirellus petfordensis sp. nov. from Australia. Ten species are redescribed: Kinonia elongata Ball, Stirellus catalinus (Beamer & Tuthill), Stirellus labiatus (Gillette), Stirellus mexicanus (Osborn & Ball), Stirellus picinus (Berg), Stirellus laetus (Melichar), Stirellus multipunctatus Duan, Webb & Zhang, Stirellus neospeciosus Duan, Webb & Zhang, Stirellus rubrolineatus (Distant), and Stirellus sagittarius (Naudé). Kinonia elongata Ball, S. catalinus (Beamer & Tuthill) and S. labiatus (Gillette), all described from the Southwestern USA, are recorded from Mexico for the first time. Stirellus picinus (Berg) is recorded from the Virgin Islands (Guana Island) for the first time. Stirellus laetus (Melichar), S. multipunctatus Duan, Webb & Zhang, S. neospeciosus Duan, Webb & Zhang, and S. rubrolineatus (Distant) are recorded from Thailand for the first time.
APA, Harvard, Vancouver, ISO, and other styles
13

Weckert, Edgar, Kurt Hümmer, Xorge A. Dominguez, Konrad Horn, and Hans Achenbacht. "The absolute configuration of kinoin C." Phytochemistry 33, no. 2 (May 1993): 447–48. http://dx.doi.org/10.1016/0031-9422(93)85536-z.

Full text
APA, Harvard, Vancouver, ISO, and other styles
14

Nair, Jayakumar R., Sanjay Bansal, and Kelvin P. Lee. "Putting the brakes on angiogenesis through a novel VEGF–KLH (kinoid) vaccine." Expert Review of Vaccines 6, no. 4 (August 2007): 491–96. http://dx.doi.org/10.1586/14760584.6.4.491.

Full text
APA, Harvard, Vancouver, ISO, and other styles
15

Trapido, Joseph. "Love and money in Kinois popular music." Journal of African Cultural Studies 22, no. 2 (November 15, 2010): 121–44. http://dx.doi.org/10.1080/13696815.2010.491316.

Full text
APA, Harvard, Vancouver, ISO, and other styles
16

van den Toren, Dr Benno. "Teaching Ethics in the Face of Africa’s Moral Crisis: Reflections from a Guest." Transformation: An International Journal of Holistic Mission Studies 30, no. 1 (January 2013): 1–16. http://dx.doi.org/10.1177/0265378812468405.

Full text
Abstract:
Though the Christian faith has in recent years increasingly shown itself to be a truly African religion, a variety of African authors such as Kä Mana, George Kinoti, Hannah Kinoti, August Shutte and Efoé Julien Penoukou have noted that sub-Saharan Africa is facing a moral crisis. This article explores this crisis in as far as it is caused by difficulties in the reception of the (Western) Christian ethic by African Christian communities. It points out that this crisis is visible in (a) double morality, (b) immorality and (c) legalism. It shows that it is both caused by rapid social change in contemporary Africa and by the way the Christian ethic was introduced with a lack of attention for (a) the relationship between worldview and ethics, (b) the social impact of changing cultural practices and (c) the importance of virtue ethics. In this way it also points to the shape Christian moral education for present-day Africa should take.
APA, Harvard, Vancouver, ISO, and other styles
17

Romano, David. "Relevance of neuroendocrine tumours models assessed by kinomic profiling." Annales d'Endocrinologie 80, no. 3 (June 2019): 144–48. http://dx.doi.org/10.1016/j.ando.2019.04.008.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

Ibrahim, Ahmed N., Daisuke Yamashita, Joshua C. Anderson, Moaaz Abdelrashid, Amr Alwakeal, Dagoberto Estevez-Ordonez, Svetlana Komarova, et al. "Intratumoral spatial heterogeneity of BTK kinomic activity dictates distinct therapeutic response within a single glioblastoma tumor." Journal of Neurosurgery 133, no. 6 (December 2020): 1683–94. http://dx.doi.org/10.3171/2019.7.jns191376.

Full text
Abstract:
OBJECTIVEDespite significant recent efforts applied toward the development of efficacious therapies for glioblastoma (GBM) through exploration of GBM’s genome and transcriptome, curative therapeutic strategies remain highly elusive. As such, novel and effective therapeutics are urgently required. In this study, the authors sought to explore the kinomic landscape of GBM from a previously underutilized approach (i.e., spatial heterogeneity), followed by validation of Bruton’s tyrosine kinase (BTK) targeting according to this stepwise kinomic-based novel approach.METHODSTwelve GBM tumor samples were obtained and characterized histopathologically from 2 patients with GBM. PamStation peptide-array analysis of these tissues was performed to measure the kinomic activity of each sample. The Ivy GBM database was then utilized to determine the intratumoral spatial localization of BTK activity by investigating the expression of BTK-related transcription factors (TFs) within tumors. Genetic inhibition of BTK family members through lentiviral short hairpin RNA (shRNA) knockdown was performed to determine their function in the core-like and edge-like GBM neurosphere models. Finally, the small-molecule inhibitor of BTK, ONO/GS-4059, which is currently under clinical investigation in nonbrain cancers, was applied for pharmacological inhibition of regionally specified newly established GBM edge and core neurosphere models.RESULTSKinomic investigation identified two major subclusters of GBM tissues from both patients exhibiting distinct profiles of kinase activity. Comparatively, in these spatially defined subgroups, BTK was the centric kinase differentially expressed. According to the Ivy GBM database, BTK-related TFs were highly expressed in the tumor core, but not in edge counterparts. Short hairpin RNA–mediated gene silencing of BTK in previously established edge- and core-like GBM neurospheres demonstrated increased apoptotic activity with predominance of the sub-G1 phase of core-like neurospheres compared to edge-like neurospheres. Lastly, pharmacological inhibition of BTK by ONO/GS-4059 resulted in growth inhibition of regionally derived GBM core cells and, to a lesser extent, their edge counterparts.CONCLUSIONSThis study identifies significant heterogeneity in kinase activity both within and across distinct GBM tumors. The study findings indicate that BTK activity is elevated in the classically therapy-resistant GBM tumor core. Given these findings, targeting GBM’s resistant core through BTK may potentially provide therapeutic benefit for patients with GBM.
APA, Harvard, Vancouver, ISO, and other styles
19

JING, QIUPING, TAO YIN, YANG WAN, HUASHAN SHI, SHUNTAO LUO, MENG LI, HAILONG ZHANG, et al. "Interleukin-13 peptide kinoid vaccination attenuates allergic inflammation in a mouse model of asthma." International Journal of Molecular Medicine 30, no. 3 (June 19, 2012): 553–60. http://dx.doi.org/10.3892/ijmm.2012.1036.

Full text
APA, Harvard, Vancouver, ISO, and other styles
20

Bizzini, B., I. Volpato, A. Lachgar, P. Cohen, and A. Gringeri. "IFNα kinoid vaccine in conjunction with tritherapy, a weapon to combat immunopathogenesis in AIDS." Biomedicine & Pharmacotherapy 53, no. 2 (March 1999): 87–89. http://dx.doi.org/10.1016/s0753-3322(99)80064-x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
21

Jarboe, John S., Jerry J. Jaboin, Joshua C. Anderson, Somaira Nowsheen, Jennifer A. Stanley, Faris Naji, Rob Ruijtenbeek, et al. "Kinomic profiling approach identifies Trk as a novel radiation modulator." Radiotherapy and Oncology 103, no. 3 (June 2012): 380–87. http://dx.doi.org/10.1016/j.radonc.2012.03.014.

Full text
APA, Harvard, Vancouver, ISO, and other styles
22

Omadjela, OA, TD Nyembue, WEP Okitolonda, NH Situakibanza, and NR Matanda. "Connaissances, attitudes et pratiques des kinois sur l'otite moyenne chronique suppurée / République Démocratique du Congo (RDC)." Revue Malienne d'Infectiologie et de Microbiologie 15, no. 2 (November 27, 2020): 53–61. http://dx.doi.org/10.53597/remim.v15i2.1733.

Full text
Abstract:
Objectifs : Analyser les connaissances, attitudes et pratiques des kinois sur l'otite moyenne chronique suppurée (OMCS) et en identifier les facteurs associés.Méthodes : Il s'agit d'une étude transversale analytique réalisée dans les communautés de Kinshasa du 1er Mars au 30 Avril 2018. Les données sociodémographiques, celles liées à la connaissance de la maladie et aux attitudes ainsi qu'aux pratiques ont été collectées. La régression logistique a été réalisée.Résultats : Sur 488 participants sélectionnés et interviewés, 261 (53,3%) n'avaient pas d'otorrhée et 227 (46,5%) avaient une otorrhée chronique suppurée. Soixante-six pourcent d'entre eux n'avaient pas accès à l'éducation sanitaire. Les deux groupes ignoraient que l'OMCS peut être causée par une infection des voies respiratoires supérieures (p = 0,144) tandis que ceux non malades ignoraient les complications de l'OMCS contrairement au groupe des malades (p < 0,0005). Les malades recouraient à la fois au traitement moderne, traditionnel et à l'automédication. Le risque d'ignorance sur les causes et complications a été multiplié par 3 chez les kinois non scolarisés et chez ceux des niveaux primaire et secondaire.Conclusion : La présente étude montre l'existence d'un réel besoin d'éducation sanitaire sur les pathologies de la sphère oto-rhino-laryngologie, particulièrement les OMCS à Kinshasa.
APA, Harvard, Vancouver, ISO, and other styles
23

Zagury, D., H. Le Buanec, A. Mathian, P. Larcier, R. Burnett, Z. Amoura, D. Emilie, et al. "IFN kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model." Proceedings of the National Academy of Sciences 106, no. 13 (March 11, 2009): 5294–99. http://dx.doi.org/10.1073/pnas.0900615106.

Full text
APA, Harvard, Vancouver, ISO, and other styles
24

Creeden, Justin F., Khaled Alganem, Ali S. Imami, F. Charles Brunicardi, Shi-He Liu, Rammohan Shukla, Tushar Tomar, Faris Naji, and Robert E. McCullumsmith. "Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases." International Journal of Molecular Sciences 21, no. 22 (November 17, 2020): 8679. http://dx.doi.org/10.3390/ijms21228679.

Full text
Abstract:
Pancreatic cancer remains one of the most difficult malignancies to treat. Minimal improvements in patient outcomes and persistently abysmal patient survival rates underscore the great need for new treatment strategies. Currently, there is intense interest in therapeutic strategies that target tyrosine protein kinases. Here, we employed kinome arrays and bioinformatic pipelines capable of identifying differentially active protein tyrosine kinases in different patient-derived pancreatic ductal adenocarcinoma (PDAC) cell lines and wild-type pancreatic tissue to investigate the unique kinomic networks of PDAC samples and posit novel target kinases for pancreatic cancer therapy. Consistent with previously described reports, the resultant peptide-based kinome array profiles identified increased protein tyrosine kinase activity in pancreatic cancer for the following kinases: epidermal growth factor receptor (EGFR), fms related receptor tyrosine kinase 4/vascular endothelial growth factor receptor 3 (FLT4/VEGFR-3), insulin receptor (INSR), ephrin receptor A2 (EPHA2), platelet derived growth factor receptor alpha (PDGFRA), SRC proto-oncogene kinase (SRC), and tyrosine kinase non receptor 2 (TNK2). Furthermore, this study identified increased activity for protein tyrosine kinases with limited prior evidence of differential activity in pancreatic cancer. These protein tyrosine kinases include B lymphoid kinase (BLK), Fyn-related kinase (FRK), Lck/Yes-related novel kinase (LYN), FYN proto-oncogene kinase (FYN), lymphocyte cell-specific kinase (LCK), tec protein kinase (TEC), hemopoietic cell kinase (HCK), ABL proto-oncogene 2 kinase (ABL2), discoidin domain receptor 1 kinase (DDR1), and ephrin receptor A8 kinase (EPHA8). Together, these results support the utility of peptide array kinomic analyses in the generation of potential candidate kinases for future pancreatic cancer therapeutic development.
APA, Harvard, Vancouver, ISO, and other styles
25

Anderson, Joshua C., Christine W. Duarte, Karim Welaya, Timothy D. Rohrbach, Markus Bredel, Eddy S. Yang, Nirmal V. Choradia, et al. "Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines." Radiotherapy and Oncology 111, no. 3 (June 2014): 468–74. http://dx.doi.org/10.1016/j.radonc.2014.04.010.

Full text
APA, Harvard, Vancouver, ISO, and other styles
26

Mahmud, Hasan, Pariya Bezrouzi, Arja ter Elst, Frank J. G. Scherpen, Kim R. Kampen, Valerie De Haas, Victor Guryev, et al. "Kinomic Profiling of Pediatric Acute Myeloid Leukemia for Detailed Cellular Insights." Blood 124, no. 21 (December 6, 2014): 1046. http://dx.doi.org/10.1182/blood.v124.21.1046.1046.

Full text
Abstract:
Abstract Acute myeloid leukemia (AML) remains a life threatening malignancy in children. Considerable progress has been made in elucidating the new diagnostic and prognostic markers over the past decades. The precise etiology remains unclear. Therefore, it is essential to evaluate the activation of the components of cellular signaling pathways to understand AML signaling and to design the most successful approach for combinational therapies and new kinase inhibitors. In this study, we used a high-throughput PepChipTMKinomics microarray system containing 976 different kinase substrates and assayed primary leukemic samples of 96 AML patients to produce an exceptionally detailed map of kinome enzymatic activities towards predefined peptide substrates. The generated profiles provide a comprehensive insight in signaling pathways active in AML patients. As expected the activation of proteins belonging to MAPK signaling, PI3K/AKT signaling, cell cycle regulation, apoptosis and insulin signaling pathways along with the signaling receptors and immune system regulators were found. Unsupervised hierarchical cluster analysis separates the AML blast profiles based on 192 peptide activities into two clusters. Cumulative incidence of relapse (CIR) was significantly higher in the patients of cluster-2. Peptide activity patterns were independent of patient characteristics. In addition, with Gaussian network modeling, a total of 540 peptides (55%) showed at least one peptide-peptide association without a prior assumptions whereas 74 peptides (7.5%) had >39 nodes suggesting to be potential interesting signaling hubs. Among these 74 peptides, 10 peptides were identified in cluster-1 and 50 peptides were in cluster-2. Thus, this total analysis defined peptides correlated to low incidence for relapse, for examples AKT1, HGFR, RGS7 and to high incidence for relapse for instance, proteins involve in MAPK pathways (RAF1, RAC1,14-3-3 eta) and cell cycle regulation and cellular growth (c-Myc, FOXO3A, RBL1). In conclusion, our study demonstrates the feasibility of peptide activity profiling to identify two active signaling network clusters in pediatric AML correlated to CIR. Highly correlated peptides belonging to cluster-2 provide stronger leads for selection of novel targets in future therapeutics. Disclosures No relevant conflicts of interest to declare.
APA, Harvard, Vancouver, ISO, and other styles
27

Willey, C. D., J. C. Anderson, C. W. Duarte, D. Zhi, X. Cui, N. V. Choradia, V. Srinivasasainagendra, J. Wang, and G. Gillespie. "Kinomic Proband Model of Radiation Response From Patient-derived GBM Xenolines." International Journal of Radiation Oncology*Biology*Physics 84, no. 3 (November 2012): S178—S179. http://dx.doi.org/10.1016/j.ijrobp.2012.07.462.

Full text
APA, Harvard, Vancouver, ISO, and other styles
28

Vandepapeliere, Pierre, François Malan, Gerhard Rogler, Anina van der Bijl, Frederik C. Kruger, Dawid S. Kruger, Geraldine Grouard-Vogel, Olivier Dhellin, Bernard Fanget, and Pierre F. Michetti. "Safety, Immunogenicity and Clinical Phase I-II Results of TNFα-Kinoid Immunotherapeutic in Crohn's Disease Patients." Gastroenterology 140, no. 5 (May 2011): S—123. http://dx.doi.org/10.1016/s0016-5085(11)60501-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
29

Houssiau, Frederic A., Aikaterini Thanou, Minodora Mazur, Edgar Ramiterre, Danny Alexis Gomez Mora, Maria Misterska-Skora, Risto Alfredo Perich-Campos, et al. "IFN-α kinoid in systemic lupus erythematosus: results from a phase IIb, randomised, placebo-controlled study." Annals of the Rheumatic Diseases 79, no. 3 (December 23, 2019): 347–55. http://dx.doi.org/10.1136/annrheumdis-2019-216379.

Full text
Abstract:
ObjectiveTo evaluate the efficacy and safety of the immunotherapeutic vaccine interferon-α kinoid (IFN-K) in a 36-week (W) phase IIb, randomised, double-blind, placebo (PBO)-controlled trial in adults with active systemic lupus erythematosus (SLE) despite standard of care.MethodsPatients with SLE (185) with moderate to severe disease activity and positive interferon (IFN) gene signature were randomised to receive IFN-K or PBO intramuscular injections (days 0, 7 and 28 and W12 and W24). Coprimary endpoints at W36 were neutralisation of IFN gene signature and the BILAG-Based Composite Lupus Assessment (BICLA) modified by mandatory corticosteroid (CS) tapering.ResultsIFN-K induced neutralising anti-IFN-α2b serum antibodies in 91% of treated patients and reduced the IFN gene signature (p<0.0001). Modified BICLA responses at W36 did not statistically differ between IFN-K (41%) and PBO (34%). Trends on Systemic Lupus Erythematosus Responder Index-4, including steroid tapering at W36, favoured the IFN-K and became significant (p<0.05) in analyses restricted to patients who developed neutralising anti-IFN-α2b antibodies. Attainment of lupus low disease activity state (LLDAS) at W36 discriminated the two groups in favour of IFN-K (53% vs 30%, p=0.0022). A significant CS sparing effect of IFN-K was observed from W28 onwards, with a 24% prednisone daily dose reduction at W36 in IFN-K compared with PBO (p=0.0097). The safety profile of IFN-K was acceptable.ConclusionsIFN-K induced neutralising anti-IFN-α2b antibodies and significantly reduced the IFN gene signature with an acceptable safety profile. Although the clinical coprimary endpoint was not met, relevant secondary endpoints were achieved in the IFN-K group, including attainment of LLDAS and steroid tapering.Trial registration numberNCT02665364.
APA, Harvard, Vancouver, ISO, and other styles
30

Ducreux, Julie, Frédéric A. Houssiau, Pierre Vandepapelière, Christian Jorgensen, Estibaliz Lazaro, François Spertini, Fabien Colaone, et al. "Interferon α kinoid induces neutralizing anti-interferon α antibodies that decrease the expression of interferon-induced and B cell activation associated transcripts: analysis of extended follow-up data from the interferon α kinoid phase I/II study." Rheumatology 55, no. 10 (June 28, 2016): 1901–5. http://dx.doi.org/10.1093/rheumatology/kew262.

Full text
APA, Harvard, Vancouver, ISO, and other styles
31

Lauwerys, Bernard R., Eric Hachulla, François Spertini, Estibaliz Lazaro, Christian Jorgensen, Xavier Mariette, Edwige Haelterman, et al. "Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid." Arthritis & Rheumatism 65, no. 2 (January 28, 2013): 447–56. http://dx.doi.org/10.1002/art.37785.

Full text
APA, Harvard, Vancouver, ISO, and other styles
32

Assier, Eric, Luca Semerano, Emilie Duvallet, Laure Delavallée, Emilie Bernier, Marion Laborie, Géraldine Grouard-Vogel, Patrick Larcier, Natacha Bessis, and Marie-Christophe Boissier. "Modulation of Anti-Tumor Necrosis Factor Alpha (TNF-α) Antibody Secretion in Mice Immunized with TNF-α Kinoid." Clinical and Vaccine Immunology 19, no. 5 (March 21, 2012): 699–703. http://dx.doi.org/10.1128/cvi.05649-11.

Full text
Abstract:
ABSTRACTTumor necrosis factor alpha (TNF-α) blockade is an effective treatment for patients with TNF-α-dependent chronic inflammatory diseases, such as rheumatoid arthritis, Crohn's disease, and psoriasis. TNF-α kinoid, a heterocomplex of human TNF-α and keyhole limpet hemocyanin (KLH) (TNF-K), is an active immunotherapy targeting TNF-α. Since the TNF-K approach is an active immunization, and patients receiving this therapy also receive immunosuppressant treatment, we evaluated the effect of some immunosuppressive drugs on the generation of anti-TNF-α antibodies produced during TNF-K treatment. BALB/c mice were injected intramuscularly with TNF-K in ISA 51 adjuvant. Mice were also injected intraperitoneally with one of the following: phosphate-buffered saline, cyclophosphamide, methylprednisolone, or methotrexate. Anti-TNF-α and anti-KLH antibody levels were assessed by enzyme-linked immunosorbent assay and the anti-TNF-α neutralizing capacity of sera by L929 bioassay. Our results showed that current treatments used in rheumatoid arthritis, such as methylprednisolone and methotrexate, do not significantly alter anti-TNF-α antibody production after TNF-K immunization. In contrast, the administration of cyclophosphamide (200 mg/kg) after immunization significantly reduced anti-TNF-α antibody titers and their neutralizing capacity.
APA, Harvard, Vancouver, ISO, and other styles
33

Anderson, Joshua C., Douglas J. Minnich, M. Christian Dobelbower, Alexander J. Denton, Alex M. Dussaq, Ashley N. Gilbert, Timothy D. Rohrbach, et al. "Kinomic Profiling of Electromagnetic Navigational Bronchoscopy Specimens: A New Approach for Personalized Medicine." PLoS ONE 9, no. 12 (December 30, 2014): e116388. http://dx.doi.org/10.1371/journal.pone.0116388.

Full text
APA, Harvard, Vancouver, ISO, and other styles
34

Ferguson, B. D., R. S. Kanteti, Y. Tan, R. Liu, M. J. Gayed, E. E. Vokes, M. K. Ferguson, A. J. Iafrate, P. S. Gill, and R. Salgia. "Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer." International Journal of Radiation Oncology*Biology*Physics 90, no. 5 (November 2014): S76. http://dx.doi.org/10.1016/j.ijrobp.2014.08.318.

Full text
APA, Harvard, Vancouver, ISO, and other styles
35

Berger, Joanna, Henrike Barbara Zech, Konstantin Hoffer, Clara Marie von Bargen, Lena Nordquist, Lara Bussmann, Fruzsina Gatzemeier, et al. "Kinomic comparison of snap frozen and ex vivo-cultured head and neck tumors." Oral Oncology 123 (December 2021): 105603. http://dx.doi.org/10.1016/j.oraloncology.2021.105603.

Full text
APA, Harvard, Vancouver, ISO, and other styles
36

CAILLOT, NOÉMIE, FABIEN COLAONE, ROMAIN BERTRAND, JENNIFER DA SILVA, SAMIR HAMDI, JONATHAN BONNEFOY, AGNES LEHUEN, BOITARD F. BOITARD, and GÉRALDINE GROUARD-VOGEL. "1190-P: IFN-Alpha Kinoid: A Promising Vaccine against Type 1 Diabetes Targeting IFN-alpha in NOD Mice." Diabetes 68, Supplement 1 (June 2019): 1190—P. http://dx.doi.org/10.2337/db19-1190-p.

Full text
APA, Harvard, Vancouver, ISO, and other styles
37

Durez, Patrick, Pierre Vandepapeliere, Pedro Miranda, Antoaneta Toncheva, Alberto Berman, Tatjana Kehler, Eugenia Mociran, et al. "Therapeutic Vaccination with TNF-Kinoid in TNF Antagonist-Resistant Rheumatoid Arthritis: A Phase II Randomized, Controlled Clinical Trial." PLoS ONE 9, no. 12 (December 17, 2014): e113465. http://dx.doi.org/10.1371/journal.pone.0113465.

Full text
APA, Harvard, Vancouver, ISO, and other styles
38

Le Buanec, H., L. Delavallee, N. Bessis, S. Paturance, B. Bizzini, R. Gallo, D. Zagury, and M. C. Boissier. "TNF kinoid vaccination-induced neutralizing antibodies to TNF protect mice from autologous TNF -driven chronic and acute inflammation." Proceedings of the National Academy of Sciences 103, no. 51 (December 8, 2006): 19442–47. http://dx.doi.org/10.1073/pnas.0604827103.

Full text
APA, Harvard, Vancouver, ISO, and other styles
39

Rogler, Gerhard, Pierre F. Michetti, Frederik C. Kruger, Anina van der Bijl, Dawid S. Kruger, François Malan, Geraldine Grouard-Vogel, Olivier Dhellin, Bernard Fanget, and Pierre Vandepapeliere. "T1234 Active Therapeutic Immunization Against TNF With a TNF-Kinoid in Crohn's Disease Patients: A Phase 1-2 Study." Gastroenterology 138, no. 5 (May 2010): S—517. http://dx.doi.org/10.1016/s0016-5085(10)62389-x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
40

Anderson, Joshua C., Douglas J. Minnich, M. Christian Dobelbower, Alexander J. Denton, Alex M. Dussaq, Ashley N. Gilbert, Timothy D. Rohrbach, et al. "Correction: Kinomic Profiling of Electromagnetic Navigational Bronchoscopy Specimens: A New Approach for Personalized Medicine." PLOS ONE 11, no. 8 (August 24, 2016): e0161986. http://dx.doi.org/10.1371/journal.pone.0161986.

Full text
APA, Harvard, Vancouver, ISO, and other styles
41

Shott, Rory H., Cathy Appanah, Catherine Grenier, Guillaume Tremblay, Xavier Roucou, and Luis M. Schang. "Development of kinomic analyses to identify dysregulated signaling pathways in cells expressing cytoplasmic PrP." Virology Journal 11, no. 1 (2014): 175. http://dx.doi.org/10.1186/1743-422x-11-175.

Full text
APA, Harvard, Vancouver, ISO, and other styles
42

Meijering, Roelien A. M., Marit Wiersma, Deli Zhang, Eva A. H. Lanters, Femke Hoogstra-Berends, Jetse Scholma, Sander Diks, et al. "Application of kinomic array analysis to screen for altered kinases in atrial fibrillation remodeling." Heart Rhythm 15, no. 11 (November 2018): 1708–16. http://dx.doi.org/10.1016/j.hrthm.2018.06.014.

Full text
APA, Harvard, Vancouver, ISO, and other styles
43

Dussaq, Alex M., Timothy Kennell, Nicholas J. Eustace, Joshua C. Anderson, Jonas S. Almeida, and Christopher D. Willey. "Kinomics toolbox—A web platform for analysis and viewing of kinomic peptide array data." PLOS ONE 13, no. 8 (August 21, 2018): e0202139. http://dx.doi.org/10.1371/journal.pone.0202139.

Full text
APA, Harvard, Vancouver, ISO, and other styles
44

Pype, Katrien. "Beads, Pixels, and Nkisi: Contemporary Kinois Art and Reconfigurations of the Virtual." African Studies Review 64, no. 1 (March 2021): 23–40. http://dx.doi.org/10.1017/asr.2020.74.

Full text
Abstract:
AbstractIn the 2016 Abiola Lecture, Mbembe argued that “the plasticity of digital forms speaks powerfully to the plasticity of African precolonial cultures and to ancient ways of working with representation and mediation, of folding reality.” In her commentary, Pype tries to understand what “speaking powerfully to” can mean. She first situates the Abiola Lecture within a wide range of exciting and ongoing scholarship that attempts to understand social transformations on the continent since the ubiquitous uptake of the mobile phone, and its most recent incarnation, the smartphone. She then analyzes the aesthetics of artistic projects by Alexandre Kyungu, Yves Sambu, and Hilaire Kuyangiko Balu, where wooden doors, tattoos, beads, saliva, and nails correlate with the Internet, pixels, and keys of keyboards and remote controls. Finally, Pype asks to whom the congruence between the aesthetics of a “precolonial” Congo and the digital speaks. In a society where “the past” is quickly demonized, though expats and the commercial and political elite pay thousands of dollars for the discussed art works, Pype argues that this congruence might be one more manifestation of capitalism’s cannibalization of a stereotypical image of “Africa.”
APA, Harvard, Vancouver, ISO, and other styles
45

Pype, Katrien. "Becoming a Diplômé in Kinshasa. Education at the Intersection of Politics and Urban Livelihoods." Diversité urbaine 15, no. 1 (November 7, 2016): 5–26. http://dx.doi.org/10.7202/1037869ar.

Full text
Abstract:
Like other cities around the globe where the state organizes exams, Kinshasa’s exétat shows the degree to which social difference and urban livelihood are intimately connected. However, despite the assumption that diplômés master book knowledge, recent changes in the practice of the exétat have transformed the meaning of a diplômé, turning that figure into a yankee, i.e., someone who possesses street knowledge that comes from experience with the informal and the illegal. More abstractly, the identity of a diplômé has become a signifier for the opposite of its taken-for-granted signified. Kinois society publicly acclaims the social and cultural capital attached to school degrees; however, most recent diplômés have obtained their degree through bribes and organized cheating.
APA, Harvard, Vancouver, ISO, and other styles
46

Grouard-Vogel, G., B. R. Lauwerys, P. Vandepapeliere, F. Colaone, P. Blanco, T. Defrance, C. Roucairol, and F. A. Houssiau. "FRI0378 Potent, Broad, and Specific Neutralizing Capacities of Polyclonal Anti-Interferon Alpha Antibodies Induced by IFN Kinoid in SLE Patients." Annals of the Rheumatic Diseases 73, Suppl 2 (June 2014): 524.1–524. http://dx.doi.org/10.1136/annrheumdis-2014-eular.3726.

Full text
APA, Harvard, Vancouver, ISO, and other styles
47

Chyuan, I.-Tsu, Hong-Tai Tzeng, and Ji-Yih Chen. "Signaling Pathways of Type I and Type III Interferons and Targeted Therapies in Systemic Lupus Erythematosus." Cells 8, no. 9 (August 23, 2019): 963. http://dx.doi.org/10.3390/cells8090963.

Full text
Abstract:
Type I and type III interferons (IFNs) share several properties in common, including the induction of signaling pathways, the activation of gene transcripts, and immune responses, against viral infection. Recent advances in the understanding of the molecular basis of innate and adaptive immunity have led to the re-examination of the role of these IFNs in autoimmune diseases. To date, a variety of IFN-regulated genes, termed IFN signature genes, have been identified. The expressions of these genes significantly increase in systemic lupus erythematosus (SLE), highlighting the role of type I and type III IFNs in the pathogenesis of SLE. In this review, we first discussed the signaling pathways and the immunoregulatory roles of type I and type III IFNs. Next, we discussed the roles of these IFNs in the pathogenesis of autoimmune diseases, including SLE. In SLE, IFN-stimulated genes induced by IFN signaling contribute to a positive feedback loop of autoimmunity, resulting in perpetual autoimmune inflammation. Based on this, we discussed the use of several specific IFN blocking strategies using anti-IFN-α antibodies, anti-IFN-α receptor antibodies, and IFN-α-kinoid or downstream small molecules, which intervene in Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathways, in clinical trials for SLE patients. Hopefully, the development of novel regimens targeting IFN signaling pathways will shed light on promising future therapeutic applications for SLE patients.
APA, Harvard, Vancouver, ISO, and other styles
48

Mathian, Alexis, Zahir Amoura, Estelle Adam, Fabien Colaone, Marco F. M. Hoekman, Olivier Dhellin, Pierre Vandepapelière, et al. "Active immunisation of human interferon α transgenic mice with a human interferon α Kinoid induces antibodies that neutralise interferon α in sera from patients with systemic lupus erythematosus." Annals of the Rheumatic Diseases 70, no. 6 (March 9, 2011): 1138–43. http://dx.doi.org/10.1136/ard.2010.141101.

Full text
Abstract:
ObjectivesInterferon α (IFNα) plays a central role in the pathogenesis of systemic lupus erythematosus (SLE) and is considered a target for its treatment. In the current study, the ability of active immunisation with a human (hu) IFNα2b Kinoid (IFN-K) to break B cell tolerance to IFNα and to induce huIFNα-neutralising antibodies in mice immunotolerant to huIFNα2b was assessed.MethodsIFN-K was manufactured by crosslinking huIFNα2b to keyhole limpet haemocyanin (KLH). Transgenic mice expressing huIFNα2b received by intramuscular injection either saline or polymerised huIFNα2b as controls, or IFN-K, emulsified in ISA51vg adjuvant.ResultsAll of the huIFNα2b-expressing mice immunised with IFN-K generated neutralising antibodies against huIFNα2b. In addition, these antibodies neutralised all 13 subtypes of huIFNα. They also neutralised IFNα activity in sera collected from 10 different patients with active SLE. However, the antibodies did not bind to huIFNγ or huIFNβ. Finally, cellular activation assays showed that immunisation with IFN-K did not induce memory T cells reactive to native huIFNα2b, whereas it did induce memory cells reactive to KLH.ConclusionThese results show that active immunisation with IFN-K induces polyclonal antibodies that neutralise all subtypes of huIFNα as well as IFNα in sera from patients with SLE by breaking humoral but not cellular tolerance to IFNα. This suggests that immunisation with IFN-K is a promising new therapeutic strategy for the treatment of SLE.
APA, Harvard, Vancouver, ISO, and other styles
49

Bizzini, Bernard, Béatrice Drouet, Daniel Zagury, Marc Abitbol, Arsène Burny, and Marie-Christophe Boissier. "Kinoids: a family of immunogens for active anticytokine immunotherapy applied to autoimmune diseases and cancer." Immunotherapy 2, no. 3 (May 2010): 347–65. http://dx.doi.org/10.2217/imt.10.16.

Full text
APA, Harvard, Vancouver, ISO, and other styles
50

Hao, Zhi-Ming, Xiao-Bao Fan, Shuang Li, Yi-Fei Lv, Hou-Qiang Su, Hui-Ping Jiang, and Hong-Hong Li. "Vaccination with Platelet-Derived Growth Factor B Kinoids Inhibits CCl4-Induced Hepatic Fibrosis in Mice." Journal of Pharmacology and Experimental Therapeutics 342, no. 3 (June 18, 2012): 835–42. http://dx.doi.org/10.1124/jpet.112.194357.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the bibliographies on the topic 'Kinogid' for other source types:
Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography