Academic literature on the topic 'Kinase inhibitor treatments'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Kinase inhibitor treatments.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Kinase inhibitor treatments"
Gäbler, Karoline, Catherine Rolvering, Valérie Palissot, Guy J. Berchem, Iris Behrmann, and Claude Haan. "Combined Inhibition of Janus and Aurora Kinase Effectively Suppresses Proliferation of JAK2 V617F-expressing Cells." Blood 118, no. 21 (November 18, 2011): 2813. http://dx.doi.org/10.1182/blood.v118.21.2813.2813.
Full textLin, Yipeng. "Kinase inhibitor therapies for Chronic lymphocytic leukaemia (CLL): SYK, BTK and PI3K inhibitors." Highlights in Science, Engineering and Technology 19 (November 17, 2022): 30–35. http://dx.doi.org/10.54097/hset.v19i.2691.
Full textTokuyama, Michio, and Tomotaka Mabuchi. "New Treatment Addressing the Pathogenesis of Psoriasis." International Journal of Molecular Sciences 21, no. 20 (October 11, 2020): 7488. http://dx.doi.org/10.3390/ijms21207488.
Full textAhmadu, Augustine A., Claire Delehouzé, Anas Haruna, Lukman Mustapha, Bilqis A. Lawal, Aniefiok Udobre, Blandine Baratte, et al. "Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor." Molecules 26, no. 15 (July 29, 2021): 4599. http://dx.doi.org/10.3390/molecules26154599.
Full textFlis, Sylwia, Ewelina Bratek, Tomasz Chojnacki, Marlena Piskorek, and Tomasz Skorski. "Simultaneous Inhibition of BCR-ABL1 Tyrosine Kinase and PAK1/2 Serine/Threonine Kinase Exerts Synergistic Effect against Chronic Myeloid Leukemia Cells." Cancers 11, no. 10 (October 12, 2019): 1544. http://dx.doi.org/10.3390/cancers11101544.
Full textGrisouard, Jean, Elisa Bouillet, Katharina Timper, Tanja Radimerski, Kaethi Dembinski, Daniel M. Frey, Ralph Peterli, et al. "Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes." Innate Immunity 18, no. 1 (November 18, 2010): 25–34. http://dx.doi.org/10.1177/1753425910386632.
Full textOkabe, Seiichi, Tetsuzo Tauchi, Seiichiro Katagiri, Yuko Tanaka, and Kazuma Ohyashiki. "Combining ABL1 Kinase Inhibitor, Imatinib and the Jak Kinase Inhibitor TG101348: A Potential Treatment for Residual BCR-ABL Positive Leukemia Cells." Blood 120, no. 21 (November 16, 2012): 3737. http://dx.doi.org/10.1182/blood.v120.21.3737.3737.
Full textBoland, Sonja, Véronique Bonvallot, Thierry Fournier, Armelle Baeza-Squiban, Michel Aubier, and Francelyne Marano. "Mechanisms of GM-CSF increase by diesel exhaust particles in human airway epithelial cells." American Journal of Physiology-Lung Cellular and Molecular Physiology 278, no. 1 (January 1, 2000): L25—L32. http://dx.doi.org/10.1152/ajplung.2000.278.1.l25.
Full textOsses, Nelson, and Enrique Brandan. "ECM is required for skeletal muscle differentiation independently of muscle regulatory factor expression." American Journal of Physiology-Cell Physiology 282, no. 2 (February 1, 2002): C383—C394. http://dx.doi.org/10.1152/ajpcell.00322.2001.
Full textBilodeau-Goeseels, Sylvie, Nora Magyara, and Coralie Collignon. "Characterization of the effects of metformin on porcine oocyte meiosis and on AMP-activated protein kinase activation in oocytes and cumulus cells." Zygote 22, no. 2 (April 12, 2013): 275–85. http://dx.doi.org/10.1017/s0967199413000075.
Full textDissertations / Theses on the topic "Kinase inhibitor treatments"
Losson, Hélène. "Combinaisons de nouveaux inhibiteurs de désacétylase d’histones 6 avec des inhibiteurs de tyrosine kinase pour le traitement de la leucémie myéloïde chronique." Thesis, Université de Lorraine, 2020. http://www.theses.fr/2020LORR0003.
Full textBreakpoint cluster region-Abelson (BCR-ABL)+ chronic myeloid leukemia (CML) patients receive tyrosine kinase inhibitors (TKIs) such as imatinib as the first-line treatment; however, some patients develop resistances and severe adverse effects. Combination treatments, especially with histone deacetylase (HDAC)6 inhibitors (HDAC6i), appear as an attractive option to prevent TKI resistances considering the capacity of HDAC6i to downregulate BCR-ABL. Moreover, HDAC6 is implicated in protein degradation pathways, so that its inhibition combined with that of the proteasome could sensitize cells to TKIs. Thus, we hypothesized that HDAC6i combined to TKIs could be effective for CML treatment. In the first part, we compared the anti-CML effects of a HDAC6i identified in our laboratory, compound 7b, to the reference HDAC6i tubacin, in combination with imatinib. Results showed that the imatinib-7b combination generated stronger anti- CML effects than imatinib-tubacin. Especially, the imatinib-7b combination elicited a potent synergistic caspase- dependent apoptotic cell death and drastically reduced the proportion of cancer stem cells in K562 CML cells, whereas it only moderately impacted various healthy cell models. Ultimately, the imatinib-7b combination decreased more potently the colony forming capacities and tumor mass formation of CML cells in a semisolid methylcellulose medium and in xenografted zebrafishes, respectively, compared to each compound alone. Mechanistically, the combination induced BCR-ABL ubiquitination and downregulation leading to a dysregulation of multiple key proteins of its downstream pathways involved in CML proliferation and survival. Results tend to demonstrate that 7b could target the second site. In the second part, we initiated a study of a novel hydroxamate-based HDAC6i, MAKV-15, and preliminary results demonstrated it triggered BCR-ABL downregulation. Accordingly, in pre-treatment with bortezomib it sensitizes CML cells to imatinib leading to enhanced caspase-dependent apoptotic death in imatinib-sensitive and imatinib-resistant CML cells. Considering that HDAC6 is reported to possess two functional catalytic sites, we finally attempted to determine which catalytic site is targeted by these HDAC6i. Taken together, our results suggest that HDAC6i potentiate the effect of imatinib and could overcome TKI resistance in CML cells and therefore such combination may represent a promising therapeutic approach for CML patients
Shor, Audrey Cathryn. "Src kinase inhibitors for the treatment of sarcomas : cellular and molecular mechanisms of action." [Tampa, Fla] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0001906.
Full textZhang, Wen. "Identification of novel pyruvate dehydrogenase kinase 1 (PDK1) inhibitors for anticancer therapeutics." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3953604.
Full textAlsfouk, Aisha. "Synthesis and biological evaluation of selective inhibitory kappa B kinase-alpha (IKKa) inhibitors for the treatment of prostate and pancreatic cancer." Thesis, University of Strathclyde, 2018. http://digitool.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=29272.
Full textD'Cunha, Ronilda Raymond. "Treatment strategies to reverse efflux transporter-mediated resistance to Tyrosine kinase inhibitors." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6563.
Full textPadi, Sathish K. R., Libia A. Luevano, Ningfei An, Ritu Pandey, Neha Singh, Jin H. Song, Jon C. Aster, Xue-Zhong Yu, Shikhar Mehrotra, and Andrew S. Kraft. "Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset." IMPACT JOURNALS LLC, 2017. http://hdl.handle.net/10150/624055.
Full textMcIntyre, Neil A. "Synthesis of ring-constrained thiazolylpyrimidines : inhibitors of cyclin-dependent kinases." Thesis, University of St Andrews, 2006. http://hdl.handle.net/10023/353.
Full textHaaning, Kelsey L. "Deletion of the phosphoinositide-3-kinase RhoGAP domain to assess inhibition of Staphylococcus aureus infection." Virtual Press, 2008. http://liblink.bsu.edu/uhtbin/catkey/1398713.
Full textDepartment of Biology
Deininger, Michael Werner Nikolaus. "STI571, a novel tyrosine kinase inhibitor : pre-clinical evaluation and application to identify downstream targets of BCR-ABL." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325912.
Full textTrousil, Sebastian. "Choline kinase inhibition as a treatment strategy of cancers with deregulated lipid metabolism." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/25146.
Full textBooks on the topic "Kinase inhibitor treatments"
Gaestel, Matthias, and K. Asadullah. Kinase targets and inhibitors in inflammation, 2007. Trivandrum, India: Transworld Research Network, 2007.
Find full textMüller, Gerhard, and Bert Klebl. Protein kinases as drug targets. Weinheim: Wiley-VCH, 2011.
Find full textHoughton, Peter J., and V. A. Polunovskiĭ. mTOR pathway and mTOR inhibitors in cancer therapy. New York: Humana Press, 2010.
Find full textservice), SpringerLink (Online, ed. Small Molecules in Oncology. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2010.
Find full textFleischmann, Roy. Signalling pathway inhibitors. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0081.
Full textMease, Philip. Biologic treatments for psoriatic arthritis apart from TNF inhibition. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198737582.003.0030.
Full textMcCormick, Frank, and Doriano Fabbro. Protein Tyrosine Kinases: From Inhibitors to Useful Drugs. Humana Press, 2010.
Find full textMcCormick, Frank. Protein Tyrosine Kinases: From Inhibitors to Useful Drugs. Humana Press, 2005.
Find full textMannhold, Raimund, Hugo Kubinyi, Michael Hamacher, Bert Klebl, and Gerhard Müller. Protein Kinases As Drug Targets. Wiley & Sons, Incorporated, John, 2011.
Find full textCyclin Dependent Kinase 5 Cdk5. Springer, 2008.
Find full textBook chapters on the topic "Kinase inhibitor treatments"
Colinge, Jacques, Uwe Rix, Keiryn L. Bennett, and Giulio Superti-Furga. "Systems Biology Analysis of Kinase Inhibitor Protein Target Profiles in Leukemia Treatments." In Information Processign in Cells and Tissues, 62–66. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-28792-3_9.
Full textHeron, Courtney E., Lindsay C. Strowd, and Steven R. Feldman. "Janus Kinase (JAK) Inhibitors." In Handbook of Systemic Drug Treatment in Dermatology, 170–76. 3rd ed. London: CRC Press, 2022. http://dx.doi.org/10.1201/9781003016786-25.
Full textRoden, Dylan F., Jennifer M. Johnson, Petr Szturz, Paolo Bossi, and Athanassios Argiris. "New and Promising Targeted Therapies in First and Second-Line Settings." In Critical Issues in Head and Neck Oncology, 277–96. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63234-2_18.
Full textRadich, Jerald, and Daniel Egan. "Goals of CML Treatment in the Tyrosine Kinase Inhibitor Era." In Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia, 53–67. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55714-2_4.
Full textGopalakrishna, R., U. Gundimeda, and Z. Chen. "Vitamin E Succinate Inhibits Protein Kinase C: Correlation with its Unique Inhibitory Effects on Cell Growth and Transformation." In Nutrients in Cancer Prevention and Treatment, 21–37. Totowa, NJ: Humana Press, 1995. http://dx.doi.org/10.1007/978-1-4612-0237-0_2.
Full textHughes, Timothy P., David M. Ross, and Junia V. Melo. "Challenges of Treatment: Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia." In Handbook of Chronic Myeloid Leukemia, 53–65. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08350-6_5.
Full textHeron, Nicola. "From Discovery to Clinic: Aurora Kinase Inhibitors as Novel Treatments for Cancer." In Protein Kinases as Drug Targets, 195–228. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527633470.ch7.
Full textLang, Gabriele E. "Treatment of Diabetic Retinopathy with Protein Kinase C Subtype &Bg;; Inhibitor." In Developments in Ophthalmology, 157–65. Basel: KARGER, 2007. http://dx.doi.org/10.1159/000098506.
Full textWilson, S. "The Role of Tyrosine Kinase Inhibitors in the Treatment of ALL." In New Agents for the Treatment of Acute Lymphoblastic Leukemia, 203–19. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-8459-3_11.
Full textDadu, Ramona, Mimi N. Hu, Elizabeth G. Grubbs, and Robert F. Gagel. "Use of Tyrosine Kinase Inhibitors for Treatment of Medullary Thyroid Carcinoma." In Medullary Thyroid Carcinoma, 227–49. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22542-5_11.
Full textConference papers on the topic "Kinase inhibitor treatments"
Polo, Maria Laura, Marina Riggio, Victoria Wargon, Sebastian Giulianelli, Silvia I. Vanzulli, Claudia Lanari, and Virginia Novaro. "Abstract 1319: Early tumor regression after endocrine and kinase inhibitor treatments in mammary carcinomas with different hormonal requirements." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1319.
Full textSantos, Tabata M., Elaine C. Campos, Renato F. Riguetti, Leandro N. Camargo, Silvia Fukuzaki, Bianca G. Rezende, Beatriz M. Saraiva-Romanholo, et al. "Effect of anti-IL17 and/or Rho-kinase inhibitor treatments on vascular remodelling in an asthma model in mice." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa4219.
Full textSwearingen, Amanda E. D. Van, Maria J. Sambade, Marni B. Siegel, Shivani Sud, Samantha M. Bevill, Brian T. Golitz, Ryan E. Bash, et al. "Abstract A03: Several rational combination kinase inhibitor treatments identified by synthetic lethality screens are efficacious in intracranial triple negative breast cancer models." In Abstracts: AACR Precision Medicine Series: Opportunities and Challenges of Exploiting Synthetic Lethality in Cancer; January 4-7, 2017; San Diego, CA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-8514.synthleth-a03.
Full textKheraldine, Hadeel, Ishita Gupta, Farhan Cyprian, Semir Vranic, and Ala-Eddin Al Moustafa. "The Combination of Dasatinib and PD L1 inhibitor prevents the progression of epithelial mesenchymal transition and dramatically blocks cell invasion of HER2 positive breast cancer cells." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0105.
Full textHenzler, Tanja, Stefanie Pohl, Nicole Schneiderhan-Mara, Stefanie Rimmele, April Livengood, Robert Kovelman, and Thomas Herget. "Abstract LB-227: Receptor tyrosine kinase phosphorylation: Simultaneous detection of 10 kinases upon inhibitor treatment." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-lb-227.
Full textNomanbhoy, Tyzoon K., Heidi E. Brown, Jiangyue Wu, Subha Vogeti, Arwin Aban, Wendy Grant, Alemayehu Senait, Shuzhen Wu, Christa Dias, and Geeta Sharma. "Abstract B23: Chemoproteomic profiling of native kinases during the treatment of cells with kinase inhibitors." In Abstracts: Fourth AACR International Conference on Frontiers in Basic Cancer Research; October 23-26, 2015; Philadelphia, PA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.fbcr15-b23.
Full textYamaguchi, A., H. Azuma, S. Sekizaki, K. Tanoue, and H. Yamazaki. "ROLE OF MEMBRANE DEPOLARIZATION IN PLATELET ACTIVATION INDUCED BY THROMBIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644473.
Full textBjerregaard, Anne-Mette, Michael V. Grandal, Camilla Frohlich, Trine Lindsted, Christina Egebjerg, Ivan D. Horac, Michael Kragh, and Mikkel W. Pedersen. "Abstract 5455: Surface accumulation of receptor tyrosine kinases upon treatment with tyrosine kinase inhibitors and resulting enhancement of activity upon treatment cessation." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-5455.
Full textLee, Kwangho, Hyoung Rae Kim, Sung Yun Cho, Hee Jung Jung, Jae D. Ha, Chang-Soo Yun, Pilho Kim, Chi Hoon Park, and Chong Ock Lee. "Abstract A284: Anaplastic lymphoma kinase (ALK) inhibitors for cancer treatment." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Oct 19-23, 2013; Boston, MA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1535-7163.targ-13-a284.
Full textKowalczyk, Piotr, Paulina Wegrzyn, Przemyslaw Zawadzki, Edyta Palacz, Ewa Trebacz, Katarzyna Wiklik, Mariusz Milik, Adrian Zarebski, Karolina Krawczynska, and Krzysztof Brzózka. "Abstract 2160: Development of selective MELK kinase inhibitors for cancer treatments." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2160.
Full textReports on the topic "Kinase inhibitor treatments"
Zheng, Jiaxi, and Haihua Yang. Clinical Benefits of Immune Checkpoint Inhibitors and Predictive Value of Tumor Mutation Burden in Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2022. http://dx.doi.org/10.37766/inplasy2022.1.0008.
Full textReiss, Michael. Type I Receptor Kinase Inhibitors - A Novel Treatment for Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, June 2002. http://dx.doi.org/10.21236/ada408030.
Full textReise, Michael. TGF-beta Type I Receptor Kinase Inhibitors - A Novel Treatment for Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, June 2003. http://dx.doi.org/10.21236/ada416442.
Full textSong, Yaowen, Shuiyu Lin, Jun Chen, Silu Ding, and Jun Dang. First-line treatment with TKI plus brain radiotherapy vs TKI alone in EGFR-mutated non-small-cell lung cancer with brain metastases: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2023. http://dx.doi.org/10.37766/inplasy2023.1.0013.
Full textEdelman, Arthur. Study of Inhibitors of Neu and Related Tyrosine-Specific Protein Kinases: Implications for the Treatment of Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 1998. http://dx.doi.org/10.21236/ada360940.
Full textEdelman, Arthur. Study of Inhibitors of Neu and Related Tyrosine-Specific Protein Kinases: Implications for the Treatment of Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 1997. http://dx.doi.org/10.21236/ada338938.
Full textPhilosoph-Hadas, Sonia, Peter Kaufman, Shimon Meir, and Abraham Halevy. Signal Transduction Pathway of Hormonal Action in Control and Regulation of the Gravitropic Response of Cut Flowering Stems during Storage and Transport. United States Department of Agriculture, October 1999. http://dx.doi.org/10.32747/1999.7695838.bard.
Full textEhrlich, Marcelo, John S. Parker, and Terence S. Dermody. Development of a Plasmid-Based Reverse Genetics System for the Bluetongue and Epizootic Hemorrhagic Disease Viruses to Allow a Comparative Characterization of the Function of the NS3 Viroporin in Viral Egress. United States Department of Agriculture, September 2013. http://dx.doi.org/10.32747/2013.7699840.bard.
Full text