Journal articles on the topic 'Keywords: spina bifida'
To see the other types of publications on this topic, follow the link: Keywords: spina bifida.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 23 journal articles for your research on the topic 'Keywords: spina bifida.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Faesal Atsani, Genta, Zanetha Mauly Ilawanda, and Ilma Fahira Basyir. "Mengenal Spina Bifida dan Pencegahannya." Jurnal Syntax Fusion 1, no. 12 (December 20, 2021): 896–903. http://dx.doi.org/10.54543/fusion.v1i12.119.
Full textAbstract:
Neural tube defects (NTD) are one of the birth defects or congenital abnormalities that occur in the brain and spine, and commonly find in newborns worldwide. Anencephaly and spina bifida are the two prevalent forms of NTD. The incidence of spina bifida happen on average 1 in 1000 cases of birth worldwide and there are 140,000 cases per year worldwide. Source searches were carried out on the online portal of journal publications as many as 20 sources from MedScape, Google Scholar and the Nation Center for Biotechnology Information / NCBI with the keywords “Neural tube defects (NTD), prevention, and spina bifida”. Spina bifida is a congenital abnormality that occurs in the womb due to a failure of closing process the neural tube during the first few weeks of embryonic development which causes the spine not completely close around the developing spinal cord nerves. NTD can ensue multifactorial conditions such as genetic, environmental, and folate deficiency. The use of folic acid supplementation starting at least 3 months before pregnancy, those are 400 mcg (0.4 mg) per day and 800 mcg per day during pregnancy can reduce the risk of developing neural tube defects such as spina bifida. Generally, spina bifida is undertaking by surgery and the regulation of patients comorbid. Public can find out prevention to avoid or reduce the risk of spina bifida so that the incidence of spina bifida can decrease along with the increasing awareness of the community regarding this disease.
2
Marshalita, Nadya. "Percutaneous Minimally Invasive Fetoscopic Surgery: Ramah Ibu dan Janin." Malang Journal of Midwifery (MAJORY) 1, no. 2 (October 30, 2019): 64. http://dx.doi.org/10.31290/majory.v1i2.1431.
Full textAbstract:
Spina bifida is a neural tube defect in which incomplete closing of the spine membrane that occurs in the lumbar and sacral. The defect of spina bifida can be motoric defect or sensoric defect. Clinical manifestation of spina bifida can be appear as limb anaesthesia, total paralysis, incontinensia urine and alvi that can cause recurrent uronary tract infection, renal insufficiency, and nephropathy reflux. Spina bifida can cause hindbrain herniation and hydrocephalus. Diagnosis of spina bifida can use 2D ultrasonography, 3D ultrasonography, and MRI. Procedure surgery of spina bifida can be done with postnatal surgery, prenatal surgery, or percutaneous minimally invasive fetoscopic surgery. Percutaneous minimally invasive fetoscopic surgery is a procedure to close the defect of fetus while intrauterine using minimal access with three or four trocar and using partial amniotic carbon dioxide insufflation (PACI) without laparotomy or hysterectomy. The adventage of percutaneous minimally invasive fetoscopic surgery compare with postnatal surgery and prenatal surgery is improve baby’s motoric function, decrease risk of ventriculoperitoneal (VP) shunt, decrease hindbrain herniation, decrease fluid in hydrocephalus, decrease risk of preterm birth, decrease risk of spontaneous membrane rupture, oligohydramnione, uterine dehiscence, uterine rupture, less pain in two days, and mother can go home from the hospital in a weeks.
Keywords: Spina bifida, percutaneous minimally invasive fetoscopic surgery, partial amniotic carbon dioxide insufflation (PACI)
3
Hukamdeen, Sajida, Muhammad Arsalan, Sidra ,. Seyal, Zahra Nasrullah, Sidra Ali, and Humna Ashraf. "Diagnostic Accuracy of Ultrasound in Detection of Spina Bifida in the First and Second Trimester Using Post-Natal MRI as Gold Standard." Pakistan Journal of Medical and Health Sciences 16, no. 7 (July 30, 2022): 909–12. http://dx.doi.org/10.53350/pjmhs22167909.
Full textAbstract:
Introduction: Antenatal ultrasound has been reported to be an effective tool for detecting neural tube defects including spina bifida. Moreover, major structural abnormalities can be detected by ultrasound examination, depending on the time of ultrasound scan. Objectives: To determine the diagnostic accuracy of ultrasound in detection of spina bifida in the first and second trimester using post-natal MRI as gold standard. Study Design: Descriptive, Cross-sectional study Study duration: 11th February 2019 to 10th August 2019 Settings: Department of Radiology, Jinnah Hospital, Lahore. Materials & Methods: A total of 125 pregnant patients/Gravida presenting in first trimester (11 to 13 weeks) & second trimester (14 to 22 weeks) assessed on dating scan, at risk for spina bifida were included. Women with pre-eclempsia and eclempsia determined on systolic BP > 140 and protein urea and history of congenital heart defects were excluded. A standard ultrasound scan was performed by the same Radiologist on the same ultrasound machine and any findings associated with the spina bifida would be noted & recorded on a predesigned Performa (Attached). Patients were followed till delivery and post-natal MRI was done to evaluate spina bifida. Presence of absence of spina bifida on USG & MRI was noted. Results: All the patients were subjected to first ultrasonography and then MRI. USG supported the diagnosis of spina bifida in 62 patients. MRI confirmed spina bifida in 63 cases. In USG positive cases, 58 were true positive and 04 were false positive. While in USG negative patients, 58 were true negative and 05 were false negative. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of ultrasound in detection of spina bifida in the first and second trimester using post-natal MRI as gold standard is 92.06%, 93.55%, 93.55%, 92.06% and 92.80% respectively. Conclusion: This study concludes that ultrasonography is a highly sensitive and accurate modality for diagnosing spina bifida, and has not only dramatically improved our ability of diagnosing spina bifida but also be a simple, economical and readily available alternative to MRI. Keywords: Spina Bifida, Ultrasonography, Sensitivity
4
Nahra, Riasat Ali, Areeba Riasat Nahra, Noor ul Mobeen, Arif Gulzar, Hafsa Riasat, and Ali Zafar. "Association of folic Acid deficiency with Central Nervous System Anomalies, Anencephaly, Spina bifida and Hydrocephalous Diagnosed by Ultrasonography during Embryonic and Fetal period." Pakistan Journal of Medical and Health Sciences 16, no. 1 (January 18, 2022): 224–26. http://dx.doi.org/10.53350/pjmhs22161224.
Full textAbstract:
Aim: To see central nervous system anomaly during pregnancy (anencephaly, hydrocephalus and spina bifida) by ultrasonography associated with folic acid deficiency/ low intake. Study design: cross sectional Site and duration: one year from Jan 2021 to Dec 2021 at Pak Red Crescent Medical & Dental College and teaching Hospital Dina Nath Multan Road Kasur. Method: There was convenient sampling. Written Consent was taken from mothers for participation in study. Pregnant mothers were examined by ultrasonography and color Doppler Machine. Designated proforma was filled by taking history of pregnant mother. Results: The mean age of mothers was 25.oo + 5.00. Most of mothers were in 3rd trimester and Gravida 2. In eleven percent cases CNS anomalies were seen among these 6% were anencephaly and 5% were Spina bifida and hydrocephalus. Conclusion: Central nervous system anomalies were found associated with folic acid low intake by mothers during pregnancy. Keywords: Anencephaly, Hydrocephalus, Spina bifida, Folic acid intake, Ultrasonography.
5
Rupcich G, Marcel, and Ricardo J Bravo. "Spina Bifida: alternative approaches and treatment, based on evidence through gait analysis." Clinical Surgery Research Communications 5, no. 1 (March 29, 2021): 01–12. http://dx.doi.org/10.31491/csrc.2021.03.067.
Full textAbstract:
Myelomeningocele results from failure of the neural tube to close in the developing fetus and is associated with neurological impairment (Incidence 1:1000 births). The level of the anatomic lesion generally correlates with the neurological deficit and ranges from complete paralysis to minimal or in some cases no motor involvement. Myelomeningocele or Spina bifida can lead to health problems, physical disabilities, and learning problems. Most commonly, associated with paralysis of the lower extremities and neurogenic bladder. Treatment requires multidisciplinary participation. The functional classification that concerns us in this review includes three types and were obtained through gait analysis. Keywords: Spina bifida; instrumental; gait analysis; kinematics and kinetics; orthotics
6
Ahmad, Shafiq, Shakeel Ahmed, Mahreen Zahra, Amir Hanif, Bilal Hussain, and Muhammad Kashif. "Management of Spina Bifida Related Non Idiopathic Club-Foot with Ponseti's Method." Pakistan Journal of Medical and Health Sciences 16, no. 5 (May 26, 2022): 278–80. http://dx.doi.org/10.53350/pjmhs22165278.
Full textAbstract:
Objective: To determine the outcome of Ponseti’s method among children with spina bifida related non-idiopathic clubfoot at a leading pediatric tertiary care children hospital of South Punjab, Pakistan. Study Design: A retrospective cohort. Place and Duration of the Study:Department of Pediatric Orthopedic Surgery, The Children’s Hospital and Institute of Child Health, Multan Pakistan from 1st January 2016 to 31st March 2022. Material and Methods: A total of 24 children (41 feet)of both genders aged up to 3 months presenting with non-idiopathic clubfoot related to spina bifida who underwent Ponseti’s method for treatment of clubfoot, with a minimum post-treatment follow up of 3 years were included. Demographic data, severity of clubfoot disease along outcomes in terms of successful correction, unsuccessful correction, relapse were noted during the study period. Results: In a total of 24 children, 15 (62.5%) were boys. Overall, mean age was calculated to be 2.6±2.2 weeks while 14 (58.3%) children were aged between 0-2 weeks. Bilateral feet were involved in 17 (70.8%) children while unilateral feet involvement was noted in 7 (29.2%) cases so total number of feet were 41. Out of these 41 feet, 38 (92.7%) had severity of clubfoot as per Pirani Score as 6. Number of casts performed were 8 or below in 39 (95.1%). Mean duration of follow up was 3.8±0.6 years. Correction of clubfoot was achieved in 36/41 (87.8%) feet. During the follow-ups, recurrence occurred in 11 (26.8%) feet. Conclusion:Initial clubfeet correction in the spina bifida cases achieved good correction rates. Rate of recurrence was considerably high with a minimum follow up period of 3 years among spina bifida associated clubfeet. Keywords: Achilles tendon, clubfoot, Pensoti’s method, spina bifida.
7
Hassaan Zahid, Lubna Ijaz, Amna Malik, Laeeq Ur Rehman, Malik M, and Nadeem Khan. "Incidence of Development of Hydrocephalus after Excision and Repair of Spina Bifida Aperta in Infants." Pakistan Journal Of Neurological Surgery 26, no. 3 (September 30, 2022): 529–35. http://dx.doi.org/10.36552/pjns.v26i3.789.
Full textAbstract:
Objective: To find out the incidence of hydrocephalus after excision and repair in infants presenting with Spina Bifida Aperta.
Materials & Methods: This prospective cohort study was conducted at the Pediatric Neurosurgery Department, Children Hospital & The Institute of Child Health, Lahore, Pakistan, from January 2021 to October 2021. A total of 62 infants of both genders presenting with spina bifida Aperta undergoing repair were included. Data of the patients, i.e., name, age, gender, head circumference, location, and width of the defect, accompanying bladder, limb anomalies, radiological, laboratory findings, and diagnosis (meningocele or meningomyelocele) were noted. Patients were followed postoperatively for 1-month, and the incidence of post-surgery hydrocephalus was noted.
Results: Out of 62 children, 36 (58.1%) were male and 24 (41.9%) female. The mean age was noted to be 138.82 days. Most children, 36 (58.1%), were found to have meningocele. The most frequent local meningocele/meningomyelocele was noted to be lumbosacral, 22 (35.5%). Post-surgery hydrocephalus was noted among 11 (17.1%) cases. No significant association of gender, age, head circumference, defect size, the maximum dimension, diagnosis (meningocele or meningomyelocele), or location was noted with post-surgery hydrocephalus among study cases (p > 0.05). No mortality was reported.
Conclusion: Meningomyelocele and lumbosacral location of the defect were among the prominent factors affecting the incidence of post-surgery hydrocephalus.
Keywords: Spina Bifida Aperta, Meningiocele, Myelomeningocele, hydrocephalus, lumbosacral
8
Malheiro, Maria Isabel Dias Costa. "Lay-leds as Educators: A self-Management Educational Programme for Adolescents with Chronic Conditions." New Trends and Issues Proceedings on Advances in Pure and Applied Sciences, no. 8 (December 22, 2017): 68–75. http://dx.doi.org/10.18844/gjapas.v0i8.2818.
Full textAbstract:
Current health guidelines aim to increase the responsibility of people with chronic conditions to self-care. Literature studies highlight educational programmes for self-management of chronic conditions as a holistic approach, involving special health needs and emotional, psychological and social needs. Lorig and Holman (with adults and the elderly population) and Malheiro (with adolescent’s with spina bifida) have proposed self-management educational programmes, using ‘Lay-leds’, as mentors on programmes. These programmes have proven effective, with positive health outcomes, such as improvement on adherence to therapy, functionality and decrease of use of emergency services and hospitalisations and reducing health costs. Thus, we propose to adapt and implement this education programme for self-management of adolescents with diabetes type 1, using Lay-leds as educators, and evaluate their effectiveness on self-management competences, quality of life, self-efficacy, physical activity motivation, self-concept, HbA1c, variability in heart rate, blood pressure, body mass index and anthropometric profile. Keywords: Self-management programme, adolescents, chronic conditions, Lay-leds.
9
Billah, Motasim, Amir Hamza, Muhammad Ali Anjum, Sarah Yunus, Sabika Hussain, and Nadia Majeed. "Variable Morphology of Sacrum in General Population." Pakistan Journal of Medical and Health Sciences 16, no. 10 (October 30, 2022): 538–40. http://dx.doi.org/10.53350/pjmhs221610538.
Full textAbstract:
Background: One of the large trilateral bones present at the base of the vertebral column is named as sacrum. The body weight transfers from trunk to pelvis and lower extremities. Different studies considering sacral morphological variations are conducted in the western world. The scope and knowledge of these studies in the eastern world is limited. Different sacral anatomies are reported by the scientists. Objective: The purpose of the study was to investigate and measure thoroughly the variable morphologies of sacrum. Study design: It is an investigational and cross-sectional study facilitated by statistical approach. Material and Methods: The study was conducted on 223 skeleton samples. These samples were preserved in the anatomy department of Mufti Mehmood Teaching Hospital Dera Ismail Khan and Bacha Khan Medical Complex Swabi during the period from October 2021 to June 2022. The human research ethical committee of the hospital approved the study. The vernier caliper was used to measure the correlation parameters of variability. The morphological features were calculated. The study also calculated the sacral variation incidence. The sacra with any kind of bony defects were excluded from the study. Results: The anatomical differences reported in the 223 samples were observed to be 59%. Out of the 223 patients the 81 were females and 142 were males. The five variations were reported in the sacral regions, while two samples have the rare sacral variations. The mean age of the included sample was observed to be 44 years. The age of the people whose sacral samples were included in the study was between 21-72 years. The percentage incidence of accessory auricular faces was observed to be 12.5%. The sacral skewness was observed in 24% cases. The 17% showed the transitional vertebra, while sacral spina bifida occulta was seen in 28% samples. Conclusion: This large scale anatomical study provides information about the apparent changes in the morphology of different sacral variables. This study provides comprehensive data about the different sacral variations. The detailed information about the human sacrum is provided. The apparent identification methods by western medical officers are also considered in this work which may help our medical staff to identify the sacral variations. Keywords: Sacrum variations, Sacrum morphology, Accessory auricular faces, Transitional vertebra and Sacral spina bifida occulta
10
Neves, Isabela Callou Sampaio, Ana Beatriz Callou Sampaio Neves, Antonio Marlos Duarte de Melo, Ana Beatriz Sousa Nunes, and Renata Sá Ferreira Brasileiro. "Fatores Maternos associados à ocorrência de Mielomeningocele: Uma Revisão Bibliográfica / Maternal Factors Associated with the Occurrence of Myelomeningocele: A Literature Review." ID on line. Revista de psicologia 15, no. 58 (December 30, 2021): 617–25. http://dx.doi.org/10.14295/idonline.v15i58.3349.
Full textAbstract:
Resumo- A mielomeningocele configura um defeito primário do tubo neural mais comum, tal defeito constitui uma das malformações congênitas mais graves do recém-nascido, uma vez que o sistema nervoso central tem início em um tubo que se desenvolve nas estruturas mais complexas do corpo humano. O defeito pode ocorrer na sua porção cranial, resultando em malformações como anencefalia e encefalocele ou na porção caudal resultando em malformações que em grupo são conhecidas como espinha bífida. A mielomeningocele é classificada como espinha bífida aberta e ocorre nas primeiras quatro semanas de gestação. O objetivo deste estudo foi identificar na literatura fatores maternos associados ao aparecimento da mielomeningocele. A coleta de dados foi realizada em outubro a novembro de 2021, nas bases de dados SciELO, Google acadêmico e BVS – Brasil utilizando as palavras chaves: “mielomeningocele”, “malformação tubo neural” e “fatores maternos”, sendo necessária também a pesquisa em livros específicos, constituindo uma amostra de 13 publicações. A deficiência de ácido fólico destacou-se como principal fator materno associado à ocorrência da mielomeningocele; além da ingestão materna de anticonvulsivantes, ingestão de fármacos antagonistas do ácido fólico, doenças como o diabetes e a obesidade, deficiência de zinco, baixas condições socioeconômicas e influências perturbadoras como a irradiação e a hipertermia materna. Conclui-se que medidas públicas no combate aos fatores maternos preveníveis são necessárias, uma vez que a mielomeningocele é uma patologia limitante, complexa, com impacto na qualidade de vida dos pacientes e de seus familiares além de requerer equipe especializada e multidisciplinar.Palavras-Chave: Mielomeningocele; Malformações; Espinha bífida. Abstract- Myelomeningocele is a primary defect of the most common neural tube, this defect is one of the most serious congenital malformations in newborns, since the central nervous system starts in a tube that develops in the most complex structures of the human body. The defect can occur in its cranial portion, resulting in malformations such as anencephaly and encephalocele, or in the caudal portion, resulting in malformations that, in group, are known as spina bifida. Myelomeningocele is classified as open spina bifida and occurs within the first four weeks of pregnancy. The aim of this study was to identify maternal factors associated with the onset of myelomeningocele in the literature. Data collection was carried out from October to November 2021, in the SciELO, Google Academic and BVS – Brazil databases using the keywords: “myelomeningocele”, “neural tube malformation” and “maternal factors”, also requiring the research in specific books, constituting a sample of 13 publications. Folic acid deficiency stood out as the main maternal factor associated with the occurrence of myelomeningocele; in addition to maternal intake of anticonvulsants, intake of drugs that are antagonists to folic acid, diseases such as diabetes and obesity, zinc deficiency, low socioeconomic conditions and disturbing influences such as radiation and maternal hyperthermia. It is concluded that public measures to combat preventable maternal factors are necessary, since myelomeningocele is a limiting and complex pathology, with an impact on the quality of life of patients and their families, in addition to requiring a specialized and multidisciplinary team.Keywords: Myelomeningocele. Malformations. Spina bifida.
11
Skryabin, E. G. "Sacralization of the L5 vertebra (Bertolotti syndrome): literature review." Genij Ortopedii 28, no. 5 (October 2022): 726–33. http://dx.doi.org/10.18019/1028-4427-2022-28-5-726-733.
Full textAbstract:
Introduction The resultant cause of pain syndrome in the lumbosacral spine in the contemporary population are dysplasia and anomalies of the development of vertebral segments, among which the sacralization of the L5 vertebra (Bertolotti syndrome) is often diagnosed. In the domestic medical literature, few publications on this pathology have been found. Methods Scientific studies for this literature review were obtained from PubMed, eLIBRARY, CYBERLENINNKA. Eighty scientific articles were used. The search for literature sources was carried out with the following keywords: sacralization of the L5 vertebra, Bertolotti Syndrome. Results and discussion In the course of the analysis, it was established that the rate of diagnosis of sacralization of the L5 vertebra ranges from 4 to 36 % of cases. It is equally detected among males and females. This pathology is frequently found in children and adolescents. Pain in the lumbar spine and sacrum is the leading clinical symptom of the disease. The severity of pain on the visual analogue scale mainly corresponds to 5 points. Scoliosis, spondylolistesis, herniated disks, spina bifida posterior may exacerbate the clinical symptoms of the associated sacralization of the L5 vertebra. During the examination of patients, plain radiography, computed tomography and magnetic resonance imaging are used. Cases of sacralization of the L5 vertebra are divided into 7 types, according to the classification of A.E. Castellvi et al. (1984). Treatment of vertebrogenic pain syndrome is carried out both conservatively (drug therapy, therapeutic blockades) and surgically (resection of the L5 transverse process, decompression of the stenotic intervertebral foramina, transpedicular fusion, radiofrequency ablation).
12
Bauer, David F., Alexandra D. Beier, Dimitrios C. Nikas, Nadege Assassi, Jeffrey Blount, Susan R. Durham, Ann Marie Flannery, et al. "Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Management of Patients With Myelomeningocele: Whether Prenatal or Postnatal Closure Affects Future Ambulatory Status." Neurosurgery 85, no. 3 (August 16, 2019): E409—E411. http://dx.doi.org/10.1093/neuros/nyz263.
Full textAbstract:
Abstract BACKGROUND Myelomeningocele (MM) is an open neural tube defect treated by pediatric neurosurgeons with prenatal or postnatal closure. OBJECTIVE The objective of this systematic review was to answer the question: What is the evidence for the effectiveness of prenatal vs postnatal closure of MM regarding short and long-term ambulatory status? Treatment recommendations were provided based on the available evidence. METHODS The National Library of Medicine PubMed database and Embase were queried using MeSH headings and keywords relevant to ambulatory status after prenatal or postnatal closure of MM. Abstracts were reviewed to identify which studies met the inclusion criteria. An evidence table was assembled summarizing the studies and the quality of evidence (Classes I-III). Based on the quality of the literature, a recommendation was rendered (Level I, II, or III). RESULTS One randomized controlled trial (Class II) and 3 retrospective cohort studies (Class III) were included as evidence. Initial ambulatory status depended on anatomic level of the neural tube defect. In the short term, prenatal closure may improve ambulatory status compared to postnatal closure. Spinal cord tethering or dermoid inclusion cyst has been associated with neurologic deterioration in infants closed in utero and after birth. Ambulation may cease in both groups over time. No long-term studies evaluated whether there is a difference in the ability to ambulate upon reaching adulthood. CONCLUSION Prenatal closure of MM may improve ambulatory status in the short term (Level II). Spinal cord tethering in both groups caused deterioration in the ability to walk. Evaluation and treatment of spinal cord tethering may help maintain ambulatory status (Level III). No studies evaluate whether prenatal or postnatal repair provides improved ability to ambulate upon reaching adulthood. The full guideline can be found at https://www.cns.org/guidelines/guidelines-spina-bifida-chapter-3.
13
Shahid Bokhari, Syed, and Muhammad Asif Qureshi. "Incidence and Trends of Neural Tube Defects in Babies Delivered at Dera Ghazi Khan Tertiary Care Center." Pakistan Journal Of Neurological Surgery 24, no. 4 (January 1, 2021): 399–404. http://dx.doi.org/10.36552/pjns.v24i4.496.
Full textAbstract:
Objective: A cross-section study was conducted to determine the incidence and trends of neural tube defects in babies delivered at a tertiary care center. And those babies who were delivered elsewhere and were brought to a tertiary care center for treatment.
Material and Methods: The Study was conducted at neurosurgery and pediatric surgery departments, Ghazi Khan Medical College and Teaching Hospital. Two thousand (n = 2000) women delivered their babies at a tertiary care hospital were enrolled, out of them 52 women who delivered babies with neural tube defects (NTDs) were further assessed. Women were interviewed and history of folic acid intake, previous baby with NTDs and family history were recorded. Tests of significance were applied to assess the significant results.
Results: Folic acid intake was occurred in n = 298 (14.9%) subjects. Association of folic acid on neural tube defects. Odds ratio showed that if a baby without intake of folic acid had 7.8 times at risk to suffer from a neural tube defect. The association was also significant (p = 0.000).
Conclusion: Neural tube defects are common in tertiary care centers its incidence was 2%. Increased incidence of NTDs was observed in babies who delivered by folic acid deficit mothers. Early childhood marriages in rural areas and cousin marriages are the main contributing factors.
Keywords: Neural tube defect, Anencephaly, Spina bifida, Hydrocephalus, Meningocele.
14
Blount, Jeffrey P., Susan R. Durham, Paul Klimo Jr, Nadege Assassi, David F. Bauer, Alexandra D. Beier, Ann Marie Flannery, et al. "Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Management of Patients With Myelomeningocele: Whether Persistent Ventriculomegaly Adversely Impacts Neurocognitive Development." Neurosurgery 85, no. 3 (August 16, 2019): E414—E416. http://dx.doi.org/10.1093/neuros/nyz265.
Full textAbstract:
Abstract BACKGROUND Myelomeningocele (MM) is the most common congenital anomaly to affect the nervous system and affects 1500-2000 newborn infants per year in the United States. It is accompanied by symptomatic hydrocephalus in approximately 70%-80% of patients. Different treatment strategies for hydrocephalus characteristically result in different effects on the size of the ventricles. OBJECTIVE The objective of this systematic review was to determine whether persistent ventricular enlargement adversely impacts neurocognitive development in patients with MM. METHODS The PubMed National Library of Medicine Medline database and Embase were queried using MeSH headings and keywords relevant to neurocognitive or intellectual development and ventricular size or morphology. Abstracts were reviewed by the authors to identify which studies met strict inclusion criteria. An evidence table was constructed that summarized the included studies and reflected the quality of evidence (Classes I–III) that each represented. A recommendation was made that is based on the quality of the evidence. RESULTS An initial abstract review utilizing strict inclusion/exclusion criteria yielded 48 studies, 9 of which underwent full-text review. There is limited and conflicting Class III evidence from 2 studies. CONCLUSION Currently, there is insufficient data to conclude that ventricular size and morphology impact neurocognitive development. The full guideline can be found at https://www.cns.org/guidelines/guidelines-spina-bifida-chapter-5.
15
Rehman, Shafiq-Ur, and Muhammad Anwar. "To Study the Outcome of Posterior Sagittal Anorectoplasty in Anorectal Malformations." Pakistan Journal of Medical and Health Sciences 15, no. 9 (September 30, 2021): 2245–47. http://dx.doi.org/10.53350/pjmhs211592245.
Full textAbstract:
Aim: To assess the effectiveness of posterior sagittal anorectplasty for the repair of anorectal malformations in terms of postoperative complications and functional outcomes. Study design: Descriptive prospective study. Place and duration of study: Sahiwal Teaching Hospital, Sahiwal. From 1st January 2016 to 31st December 2019. Methodology: Forty-two children with high/intermediate anorectal malformations, who underwent posterior sagittal anorectoplasty, were included in the study. Patients with low variety anorectal malformations, recto vestibular/ano vestibular fistula, persistent cloaca and patients with sacral dysraphism, spinal dysraphism, myelomeningocele spina bifida occulta and menifesta were excluded. Demographic information included age, gender, weight, type of anorectal malformation, type of surgery performed, operation time and hospital stay. Immediate post-operative complications were also noted. Bowel habits, constipation and faecal incontinence were evaluated in all patients during the follow up period. Results: Thirty-one (73.80%) were males and 11(26.19%) were females and mean age was 1.72 years. The mean weight at the time of operation was 11.00 kg. High variety anorectal malformations were 14(33.33%) and intermediate were 28(66.66%). Rectourethral fistula 25(59.52%) was most common variety seen in males. Recto bulber urethral fistula in 17(40.47%) and recto prostatic urethral fistula in 8(19.04%) patients were seen. Anal agenesis without fistula 7(16.66%) was most common anomaly in females. Overall complication rate was 15(35.71%). Constipation 11(26.19%) was most common post-operative complication. True fecal incontinence was seen in 3(7.14%) patients. Strong and effective squeeze of anal sphincter was seen in 39 (92.85%) patients and satisfactory bowel habits were present in 37 (88.08%) patients. Conclusion: Posterior sagittal anorectplasty is a useful procedure in the management of high/intermediate anorectal malformations, precise identification and reconstruction of muscle complex result in good anatomical and functional outcome. Immediate post-operative complication rate is also low. Keywords: Anorectal malformations, Posterior Sagittal Anorectoplasty, Postoperative complications, Functional outcomes
16
nissa, Fakharu, Rasheeda Hingoro, and Waqarunissa Ahmed. "Factors Associated with Iron and Folic Acid Deficiency Among Pregnant Women a Cross-Sectional Hospital-Based Study." Pakistan Journal of Medical and Health Sciences 16, no. 2 (February 26, 2022): 537–39. http://dx.doi.org/10.53350/pjmhs22162537.
Full textAbstract:
Current study is a cross-sectional hospital-based study and its comparative results were highly significant (<0.005). When 200 pregnant women after dividing into two different groups compared with each other regarding their folic acid and iron intake during three trimesters of their pregnancies results were significant (<0.005). In the multiple regression analysis three variables iron, folic acid and hemoglobin levels were analyzed. In Group X, and Group Y the levels of iron (167.2± 3.12, 165.12±4.11, 164.33±2.13), (67.1± 4.12, 15.12±6.11, 14.33±2.13) folic acid (16.4±2.4, 16.4±1.5, 17.1±2.3), (6.4±1.4, 10.4±1.8, 5.1±1.3) and hemoglobin (15.2±3.6, 15.5±2.11, 15.5±3.12) (10.2±3.6, 7.5±32.10, 8.5±11.12) were calculated respectively. The percentage mean standard deviation of Spinal bifida, Anencephaly and Premature birth in Group X and Group Y was (1.21±1.01, 1.11±1.11, 1.22±2.2 ), (7.41±5.3, 3.17±2.14, 17.12±12.22). Keywords: Spinal bifida, Anencephaly, anemia, folic acid, iron
17
Tahapary, Prisca A., and Putri Nilasari. "PENGGUNAAN ELECTRONIC PAIN DIARY DALAM PENGKAJIAN NYERI KRONIS PADA ANAK: KAJIAN LITERATUR SISTEMATIK [THE USE OF AN ELECTRONIC PAIN DIARY IN THE ASSESSMENT OF CHRONIC PAIN IN CHILDREN: A STUDY OF THE SYSTEMATIC LITERATURE]." Nursing Current: Jurnal Keperawatan 10, no. 1 (June 21, 2022): 51. http://dx.doi.org/10.19166/nc.v10i1.4895.
Full textAbstract:
<p><em>The provision of nursing care to children has an important component, namely assessment and adequate pain management. Children and adolescents can experience chronic pain due to the type of disease they suffer from such as juvenile idiopathic arthritis, sickle cell anemia, cancer, spina bifida, hemophilia, and others. The complexity of chronic pain requires a quantifiable and valid assessment in order to evaluate comprehensive pain management. One method of assessing pain in children that can incorporate technological advances is the use of an electronic pain diary. The use of this technology can be applied to clinical practice for pain assessment that has a proven quality index. The purpose of this study was to determine the use of electronic pain diaries in the assessment of chronic pain in children from various article sources. The method used in this systematic literature review process is a simplified approach. The databases used in the literature search consisted of Science Direct, Proquest, Scopus, Ebsco, Scholar, Wiley, and Pubmed. Inclusion criteria are articles in full text, in Indonesian and English, year of publication for the last five years from 2017 to 2021. Exclusion criteria are article topics on electronic health records, article topics on portable monitors, and literature review articles. During the search process, the author uses several keywords such as; “electronic pain diary”, pediatric pain assessment, pain diary. The search found eight articles with the result that the pain assessment method in children can be collaborated with technology, namely the electronic pain diary. Deviceelectronic pain diary can assist in the treatment process for chronic pain in children and canused as a standard in collecting data related to chronic pain experienced by children and adolescents. The device has been integrated with a software program that has been adapted to the age and development of children and adolescents.</em> </p><p><strong>BAHASA INDONESIA ABSTRAK </strong>Nyeri merupakan bentuk pengalaman sensorik dan emosional yang tidak menyenangkan dan berhubungan dengan adanya suatu jaringan yang mengalami kerusakan secara aktual maupun potensial. Untuk mendokumentasikan dan mengobati nyeri kronis secara efektif membutuhkan cara pengukuran yang valid dan dapat digunakan dalam praktik klinik. Penggunaan <em>electronic pain diary</em> ini menjadi salah satu inovasi modern yang memiliki kemudahan pemantauan data elektronik untuk mengidentifikasi faktor-faktor yang memperburuk atau menghilangkan rasa nyeri, serta mendorong pasien atau dokter untuk memodifikasi pengobatan dan lebih memahami gejala dan manajemen nyeri. Tujuan penelitian ini untuk mengetahui penggunaan <em>electronic pain diary</em> dalam pengkajian nyeri kronis pada anak dari berbagai sumber artikel. Metode yang digunakan dalam proses pencarian kajian literatur sistematik ini dengan pendekatan simplified approach. Adapun tujuh database yang digunakan terdiri dari <em>Science Direct, Proquest, Scopus, Ebsco, Scholar, Wiley,</em> dan Pubmed sejak tahun 2017 sampai 2021 dengan total yang didapatkan berjumlah delapan artikel. Selama proses pencarian, penulis menggunakan beberapa kata kunci seperti; “<em>electronic pain diary</em>”, <em>pediatric pain assessment, pain diary</em>. Setelah didapatkan artikel yang relevan kemudian dilakukan analisis. Metode pengkajian nyeri pada anak dapat dikolaborasikan dengan teknologi yaitu electronic pain diary dan ditemukan bahwa dapat membantu dalam proses penanganan untuk nyeri kronis pada anak. <strong> </strong></p><p> </p>
18
Choudhary, Richa, and Dr Rishikant Sinha. "STUDY OF FOETAL ULTRASOUND OF NEUROECTODERMAL ANOMALIES IN ANTENATAL MOTHERS." International Journal of Medical and Biomedical Studies 3, no. 11 (December 11, 2019). http://dx.doi.org/10.32553/ijmbs.v3i11.791.
Full textAbstract:
Objectives: This study was to evaluate the incidence, prevalence and various types of neuroectodermal anomalies of foetuses in antenatal mothers.
Methods: All pregnant women with intrauterine pregnancy of gestational age ranging from 12 weeks to Post-term cases were included for this study. We were studied on 21450 ultrasound scan of antenatal mothers, who were come for routine check up. Among them 50 foetuses anomalies were found.
Results: Data was analyzed by using simple statistical methods with the help of MS-office software. All data was tabulated, and percentage was calculated.
Conclusions: Neuroectodrmal anomalies of foetuses were commonly seen in maternal age group of 30-40 years and prevalence was 0.23%. Anencephaly and hydrocephalus associated with spina bifida were seen in most of the CNS anomalies foetuses. Spina bifida in the lower lumbar region associated with a meningocoele or myelomeningocoele was the most common. Hence, ultrasound is an effective investigative modality for in utero screening of congenital anomalies. Ultrasound imaging in antenatal period practically gives an anatomical record of the developing foetus. So that early detection of anomalies especially in first and early second trimester helps in planning termination, interventions and further management of neuroectodermal anomalies foetus.
Keywords: Antenatal mothers, Ultrasound scan, Neuroectodermal anomalies
19
Espín, Gabriela, Alicia Torres, José Rodolfo Bernal, Jesús Castro, Andrea Paez, Byron Sanunga, Carlos Morales, and Enrique Castro. "Giant occipital encephalocele in a newborn; surgical treatment. Case report." Peruvian Journal of Neurosurgery 4, no. 1 (January 1, 2022). http://dx.doi.org/10.53668/2022.pjns41073.
Full textAbstract:
Introduction: Neural tube defects (NTD) are congenital malformations that are caused by the lack of fusion of the neural tube during the embryonic period, exposing the nervous tissue to the outside. There are different types, and they can be cranial (anencephaly and encephalocele) and spinal (spina bifida). The encephalocele is a protrusion or herniation of the intracranial content, through the bony defect of the skull. In this article, we report the case of a patient diagnosed with occipital encephalocele, while reviewing the neurosurgical treatment performed in our hospital. Clinical Case: We present the case of an 8-day-old male neonate, the son of a 36-year-old diabetic mother, with a prenatal ultrasound diagnosis of occipital encephalocele, evidenced at 16 weeks of gestational age. The patient underwent surgery, performing a plasty of the occipital encephalocele; he presented as a mediate complication infection of the surgical wound that was resolved with antibiotic treatment, later presenting a favorable evolution. Conclusion: The extension and nature of the hernial content of the encephalocele determine its prognosis, as well as immediate treatment, which can reduce postoperative complications. Keywords: Encephalocele, Neural Tube, Spinal Dysraphism, Nerve Tissue (Source: MeSH NLM)
20
MAO, Baohong, Chichen ZHANG, Liping YANG, Yanxia WANG, Chunhui SU, Huining ZHAO, Yawen SHAO, and Qing LIU. "Visualizing the Research Hotspots and Emerging Trends in Neural Tube Defects: A Review." Iranian Journal of Public Health, June 13, 2020. http://dx.doi.org/10.18502/ijph.v49i3.3122.
Full textAbstract:
Background: Neural tube defects (NTDs) are among the second most common serious birth defects and constitute a major cause of infant death. Research about NTDs has achieved tremendous progress over the last 50 years. Methods: Visualization analysis has been used to explore the hot topic and their emerging trends in NTDs research domain. The scientific literature of research for NTDs has been retrieved from Web of Science™ Core Collection (1966–2014) databases, and final acquire 9125 related bibliographic records, then analyze time trend, distribution of journals, hot keywords, and try to explore the hot topic and their emerging trends in NTDs research domain using Histcite and CiteSpace. Results: The number of publications about NTDs have shown an increased tendency over the last 50 years although there was on a slight decline. Birth Defects Research Part A published the most articles on NTDs research, followed by Lance and Teratology, and the Lancet had the greatest number of total citations. The largest cited frequency keywords was the “Folate”, followed by “Pregnancy”, “Prevention”, and “Spina bifida”. The research hotspots in NTDs research were homocysteine, anencephaly, and screening. Conclusion: With the help of visualization analysis, we explore a quantitative and efficient way of understanding the NTDs knowledge field.
Keywords: Visualization analysis; Neural tube defects; Scientometrics; CiteSpace
21
Satyawan, Yopie T., Arry Rodjani, and Irfan Wahyudi. "URINARY CONTINENCE DIVERSION IN CHILDREN WITH NEUROGENIC BLADDER." Indonesian Journal of Urology 22, no. 1 (April 1, 2015). http://dx.doi.org/10.32421/juri.v22i1.98.
Full textAbstract:
Objective: We evaluate the initial experience of the implementation of the urinary diversion procedure in patients with neurogenic bladder continence in children. Material & method: The study was conducted retrospectively by collecting data contained in patient medical records of patients who come for treatment to Cipto Mangunkusumo Hospital Jakarta, from 2003 to 2012, and by interviews with parents of patients over the phone or when the patients control to the clinic. The patient is a child (age 0-18 years), diagnosed with congenital neurogenic bladder, and had urinary diversion continence procedure. Results: There are eight cases with urinary diversion continence undertaken in Cipto Mangunkusumo Hospital and found only 7 cases met the inclusion criteria with more girls than boys. Common etiology was spina bifida (57%). Most of the patients complained of recurrent UTI, and the most techniques used are Mitrofanoff (72%) with complications 33%. Conclusion: Urinary diversion continence procedure that has been done in Urology of Cipto Mangunkusumo Hospital is Mitrofanoff-Monti. Of the total of seven cases performed, the initial evaluation gives good results after urinary diversion continence procedure. Improved quality of life of patients with the achievement continence, overcome recurrent UTI problems and kidney function can be retained.
Keywords: Neurogenic bladder, Mitrofanoff techniques, Yang-Monti.
22
Abedalrahman, Sarab K., Fatima K. Khalid, Mahabad S. Ali, and Sheelan MS Hasan. "Concomitant COVID 19 Infection And NTDS: 68 Patient Case Series." World Family Medicine Journal /Middle East Journal of Family Medicine 20, no. 9 (September 2022). http://dx.doi.org/10.5742/mewfm.2022.9525142.
Full textAbstract:
Introduction: Documented articles have determined that viral illness during early pregnancy and several antiviral drugs are associated with an increased risk for neurodevelopmental congenital anomalies of the newborn. These include NTDs, the most common and severe malformations of spinal cord (spina bifida) or brain (anencephaly, encephalocele, hydrocephalus), which develop within 6 weeks of pregnancy with an incidence of one in 1000 neonates worldwide and they cause lifelong neurological complications. The aim of this study is to describe the clinical characteristics of simultaneous cases of COVID 19 in pregnant women with neural tube defects in their newborns. Patient and methods: This is descriptive study case series including cases of Neural Tube Defects when their mothers were affected with COVID-19 infection that was reported in Zahko Maternity hospital. Those in the labour unit were enrolled in this study and the cases was collected during the period 1st January 2020 and 1st January 2022. The information collected through direct interview with the mothers through questionnaire includes the information about the socio-demographic, obstetrical history and history of COVID 19 infection, severity presence of fever and type of medication received. Results: Regarding the general and obstetrical history of the patients, the current study revealed that the affected age group of mothers was as follows; 28 (41.2%) of them (26-30 years), and 15 (22.1) of them (> 35). Anemia and fever in the 1st trimester were found in 54 (79.4%) of them. Alcohol intake was reported in 2 (2.9%) of them, consanguinity in 19 (27.9%) of them, female newborns constituted 38 (55.9%), gestational diabetes mellitus in 1 (1.5%), diabetes mellitus in 6 (8.8%), and hypertension in 5 (7.4%). The drugs received during pregnancy, were as follows; antibiotics; all patients 100%; antihypertensive drugs received by 14 (20.6%), antipyretics 29 (42.6%), antacids 21 (30.9%), and antifungals 16 (23.5%). Conclusions: the COVID19 infection may be blamed as a cause of NTDs, and further research about the pathophysiology is needed. Keywords: Concomitant COVID 19 & Neural Tube Defects, Case Series of COVID 19 & Neural Tube Defects
23
Jha, Dr Anju, Dr Sovendu Jha, Dr Amit Kumar, Dr Madhushree Mukhopadhyay, Dr Anupriya Jha, and Dr Kumar Anand. "EVALUATION OF ASSOCIATION OF CLEFT LIP AND CLEFT PALATE WITH CERVICAL VERTEBRAL ANOMALIES: A LATERAL CEPHALOGRAPH STUDY." International Journal of Medical and Biomedical Studies 3, no. 8 (September 5, 2019). http://dx.doi.org/10.32553/ijmbs.v3i8.511.
Full textAbstract:
The precise origin of cervical vertebral anomalies is still unstated, but it has been suggested that the association between abnormal development of cervical vertebrae and the maxilla and the mandible might be caused by a developmental fault of the mesenchyme as these structures might be dependent on the similar para-axial mesoderm. Hence it is appropriate to focus on this area of research and to consider the craniofacial morphology as an important diagnostic tool in Orthodontic treatment planning. The present study was planned to evaluate the association of Cleft lip and Cleft palate with cervical vertebral anomalies.
The present study was planned in Department of Pediatric and Preventive Dentistry, Buddha Institute of Dental Sciences & Hospital, Patna, Bihar, India. Thirty cases of Cleft Lip and Cleft Palate (CLCP) patients were enrolled in the present study. The age of the patients ranged from 5 years to 15 years. The cleft sample were subdivided into patients with CP only, and unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP). Radiographs were examined on a film viewer by a single examiner. The profile of first four cervical vertebrae and Atlanto Occipital Articulation were structurally traced on an acetate paper with 3H lead pencil under optimum illumination and Cervical Vertebral Anomalies (CVA) were registered and categorized into Posterior Arch Deficiencies - PAD (dehiscence and spina bifid) and fusion.
The present study concludes the association between cleft lip and palate and Cervical Vertebral Anomalies indicating that CVA may be implicated as the etiology of cleft lip and palate. The present study showed a specific relation between the Cleft Palate and cervical anomalies and the vertebral anomalies following a specific pattern in different types of cleft was found to be PAD which occurred more frequently in UCLP and CP only and fusion occurring significantly more often in BCLP.
Keywords: Cleft Lip and Cleft Palate; Cervical Vertebral Anomalies; Dehiscence; Fusion; Lateral Cephalograph