Academic literature on the topic 'Kalimanta Tumor'

Background: Tumour is an uncontrolled swelling of tissue. Tumour caused by uncontrolled proliferation abnormal tissue and cell. Based on the nature of the tumour, there are two types of tumours, that is benign tumour and malignant tumour. The malignant tumour can cause death while benign tumour only aggravate the surrounding tissue.The high incidence of tumors in various countries, including Indonesia, rarely finds research on the prevalence of oral tumors, especially in East Kalimantan, especially the capital city of Samarinda. Objective: This research is to find out the incidence of oral cavity tumour at RSUD Abdoel Wahab Sjahranie periode 2016-2020 . Method: Used was a descriptive observational method retrieving secondary data in the form of medical records. The sampling method used in this research was the purposive sampling method. Results: the profile of patients with oral cavity tumour at Regional General Hospital Abdoel Wahab Sjahranie 2016-2020 are as follows the age group with the highest incidence is 46-55 years: 32 patients (24,8%), The highest incidence by gender were women: 78 patients (60.5%) and man: 51 patients (39,5%). Most of the tumour were found in the mandible: 65 patients (50,4%). Conclusion: The prevalence of oral cavity tumour is higher in female patients than male patients.

Lymphocystis virus has been implicated as the cause of severe infection, mortality, and economic loss in farmed giant snakehead (Channa striata) or gabus fish in Mandiangin South Kalimantan. In Kalimantan, the fish is locally known as Haruan fish and considered to have health-related benefits to human due to its high albumin content. This study aimed to determine the LCDV in gabus fish through histopathological and PCR investigation. Infected LCDV fish have a cluster of warts growths in the skin or fin of a walleye. Infected fishes with an average of total length of 15 cm and weight of 150 g were collected from local net cages and earthen ponds. They were transferred into a laboratory, anesthetized, and then subsequently killed by organ dissection. The infected fish tumors were aseptically cut out for histological study and PCR detection. Primer used was forward GII F: 5 ‘TGG GAT TCC AAY GGT CAA TTA-3’ with target band of 468 bp (for genotype-IIi LCDV) and primer reverse R: 5’TTA GAT TAT TGG GCA GCG TT-3' with target band of 250 bp (for genotype-II LCDV) and GIII F: 5' AGG AAA TAA CCG CAG TA GAA TGCA. Lymphocytosis in infected fish showed multifocal to diffuse white, round, firm, papilloma or tumor-like nodules on the skin of the body, fins, eyes, and mouth. The hypertrophied cell was surrounded by a thick smooth hyaline capsule. Stress condition caused by high population density, nutrition deficiencies, decreased dissolved oxygen, suboptimal water quality, and handling may increase the appearance of LCDV symptoms. The result of the present study revealed that histopathology and PCR could be used to diagnose LCDV infection.

Breast cancer is reported to rank fifth among all types of cancer with a case of death of 6.6%. In the Central Kalimantan region, early examinations of cancers including breast cancer were carried out and 247 tumors in the breast were identified (1.76%). Kelakai (Stenochlaena palustris) as one of the typical plants of Kalimantan which contain natural chemical constituents has been reported to be effective as an anti-inflammatory and antioxidant, so that with this potential can be developed to overcome diseases associated with it, one of them is breast cancer. This study aimed to examine the cytotoxicity of MCF-7 breast cancer cells using ethanol extract. The cytotoxicity assay of kelakai extract against MCF-7 cells conducted in vitro by the MTT reduction method. The variation of concentration used is 1000; 500; 250; 125; 62.5; 31.5; and 15.625 µg/ml, doxorubicin as a positive control was performed in a concentration of 1 μg / ml. The results of the cytotoxicity assay showed that the kelakai extract had a toxic effect on MCF-7 cells with an IC50 value of 493.57 µg / ml.

Latar Belakang. Pasien dengan tumor payudara palpabel yang datang berobat memerlukan diagnosis cepat dan akurat untuk membedakan tumor tersebut ganas atau jinak serta lebih menguntungkan secara finansial dibandingkan biopsi terbuka melalui prosedur operatif. Prosedur triple test yang terdiri dari pemeriksaan klinis payudara, mammografi dan biopsi aspirasi jarum halus, memberikan hasil akurasi diagnosis yang baik. Namun pada kenyataannya tidak semua rumah sakit terutama rumah sakit di daerah memiliki fasilitas mammografi. Untuk menegakkan diagnosis tumor payudara palpabel di rumah sakit daerah dilakukan pemeriksaan klinis payudara dan biopsi aspirasi jarum halus. Penelitian ini dilakukan untuk menilai akurasi kombinasi dua pemeriksaan yaitu pemeriksaan klinis payudara dan biopsi aspirasi jarum halus dalam menegakkan diagnosis tumor payudara palpabel. Metode. Dilakukan penelitian prospektif pada 393 pasien tumor payudara palpabel, dengan melakukan pemeriksaan klinis payudara, biopsi aspirasi jarum halus dan biopsi terbuka dengan pemeriksaan histopa- tologi sebagai pemeriksaan baku emas di RSUD dr Soedarso Pontianak, Kalimantan Barat selama 7 tahun (2006–2013). Hasil. Pemeriksaan klinis payudara menunjukkan sensitivitas 90,8%, spesifisitas 92,8%, nilai duga positif 95,2% dan akurasi 91,6%. Pemeriksaan biopsi aspirasi jarum halus menunjukkan sensitivitas 97.5%, spesifisitas 99,4%, nilai duga positif 99,6%, dan akurasi 98,2%. Pada kombinasi dua pemeriksaan yang keduanya positif (konkordan), menunjukkan sensitivitas 97,7%; spesifisitas 99,3%; nilai duga positif 99,5%, dan akurasi 98,3%. Likelihood ratio atau rasio kemungkinan positif/ RK+ sebesar 139,5 dan RK negatif /RK– sebesar 0,02. Kesimpulan. Akurasi dua pemeriksaan bila ke dua pemeriksaan positif (konkordan) dalam mendiagnosis tumor payudara palpabel adalah 98,3%. RK+ sebesar 139,5 dan RK negatif /RK– sebesar 0,02. Berdasarkan hasil penelitian ini, kombinasi dua pemeriksaan dapat direkomendasukan sebagai alat diagnosis alternatif untuk mendiagnosis tumor payudara palpabel

Pandemi Covid-19 menimbulkan dampak pada semua sendi kehidupan masyarakat, salah satunya adalah banyaknya fresh graduate lulusan strata 1 belum mendapatkan pekerjaan. Di sisi yang lain perubahan metode pembelajaran daring secara spontan untuk menekan penyebaran virus menimbulkan kendala dan hambatan bagi siswa dan orang tua dalam beradaptasi. Orang tua cenderung menggunakan tenaga bimbingan belajar nonformal untuk menunjang tingkat pemahaman materi yang diberikan di sekolah untuk mengatasi kendala tersebut. Bimbel Enggon Sin_Au_Qu merupakan lembaga penyedia jasa pendidikan nonformal dengan jangkauan wilayah Surabaya, Sidoarjo, Gresik, Malang, Semarang bahkan Kalimantan mendapatkan dampak positif dari pembelajaran daring dengan mengalami peningkatan permintaan jasa tutor sehingga menyerap tenaga terdidik tersebut. Penyerapan tenaga terdidik tersebut dengan basis metode sociopreneur. Permasalahan yang dialami oleh manajamen adalah tutor yang mayoritas berasal dari freshgreaduate. Bimbel Enggon Sin_Au_Qu melakukan metode pendampingan dengan memfasilitasi tutor untuk mengikuti training online pengembangan SDM, pembenahan manajemen Enggon Sin_Au_Qu dalam mengelola tutor dan pengguna jasa serta mengembangkan sistem promosi untuk memperluas pemasaran. Hasil yang dicapai sebagai sociopreneurship adalah : 1) Pengembangan potensi sumber daya tutor, 2) Sistem manajemen menjadi terkoordinir 3) Bimbel Enggon Sin_Au_Qu dikenal oleh masyarakat luas. Dengan demikian, Enggon Sin_Au_Qu sebagai wadah usaha yang mampu menumbuhkan potensi ekonomi yang dapat dinikmati berbagai pihak yang terlibat

Waterfront might be conceived as an entry to places where urbanity evolves. The physical process arises from the socio-political and economic development of its society. It entails a complex social and ecological processes constantly occur and how they interfere with each other. This paper analyses the ethnography of place in Tumok, a traditional floating kampung in Sambas, in the perspective of socio-ecology. This study is in an initial part of an ongoing Ph.D research on the urban political ecology of river settlements. Up to this stage, research findings have shown that becoming such a part of the past riverine culture in the context of present land-oriented urban culture has raised a new insight about how to view the urban waterfront.Keywords: riverine culture; socio-ecological process; spatial ethnography; urban kampung ISSN: 2398-4287© 2017. The Authors. Published for AMER ABRA by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, UniversitiTeknologi MARA, Malaysia.

Pandemi Covid-19 memberikan dampak pada sendi kehidupan, termasuk pendidikan. Pemerintah Indonesia menerapkan kebijakan PJJ (Pembelajaran Jarak Jauh) untuk menekan dampak lebih besa` PJJ membuat adaptasi lembaga pendidikan non formal Enggon Sin_Au_Qu yang merupakan lembaga penyedia jasa pendidikan non formal dengan jangkauan wilayah Surabaya, Sidoarjo, Gresik, Malang, Semarang bahkan Kalimantan. Enggon Sin_Au_Qu mengalami peningkatan permintaan jasa sehingga manajemen melakukan penambahan tutor. Dengan pengembangan yang terjadi maka perlu dilakukan analisa tentang kesetaraan gender di pendidikan non formal Enggon Sin_Au_Qu. Data yang digunakan adalah data sekunder dengan pendekatan deskriptif kuantitatif. Analisa yang dilakukan memberikan hasil berupa gambaran atau mapping peningkatan jumlah siswa yang termasuk Gen-Y dan I-Gen antara tahun 2019 sampai dengan tahun 2021. Dari sisi kuantitas tutor di Enggon Sin_Au_Qu sebanyak 18 orang, didominasi oleh tutor perempuan sebanyak 56% sedangkan sisanya adalah 44% orang adalah tutor laki-laki. Kuantitas tutor perempuan yang lebih besar tak terlepas secara psikologis perempuan berperan dalam membentuk kepribadian peserta didik dalam pembentukan sifat kejujuran, bersikap lemah lembut, memiliki rasa sabar, pantang menyerah dan menanamkan rasa adil, sehingga perempuan lebih dominan dalam peran membentuk dan mengembangkan peserta didik. Gambaran umum data peran tutor terhadap siswa yaitu peran tutor perempuan sebesar 39% terhadap perkembangan Gen-Y dan I-Gen di Enggon Sin_Au_Qu, sedangkan peran tutor laki-laki lebih besar yaitu 61%. Dengan data tersebut maka secara kuantitas tutor perempuan lebih banyak, tetapi secara kualitas tutor laki-laki mempunyai peran lebih besar dalam pengembangan pendidikan non formal Bimbel Enggon Sin_Au_Qu. Dengan demikian dapat disimpulkan bahwa kesetaraan gender merupakan kata kunci untuk pengembangan bisnis pendidikan non formal Enggon Sin_Au_Qu.

Pengabdian yang dilakukan ini terdiri dari tiga tahapan yaitu perencanaan, pelaksanaan, dan evaluasi. Pada tahap pertama atau tahap perencanaan, dilakukan penyusunan rencana sebelum pelaksanaan kegiatan dan mensosialisasikan kegiatan pengabdian kepada masyarakat berupa kewirausahaan ini kepada target sasaran tentang adanya produk es krim sehat dari ekstrak kayu bajakah. Lokasi pemasaran akan kami jangkau adalah kampus dan lingkungan masyarakat. Inovasi dalam pembuatan es krim ini diharapkan mampu menarik minat konsumen untuk membeli produk “es krim sehat dari ekstrak kayu bajakah” ini dan memiliki kepuasan tersendiri. Tumbuhan akar bajakah merupakan salah satu tumbuhan yang secara empiris dimanfaatkan oleh masyarakat pedalaman Kalimantan sebagai obat tradisional. Kandungan senyawa metabolit sekunder ini dapat mengobati berbagai penyakit degeneratif, seperti diabetes, kanker, tumor dan lain-lain. Inovasi yang dilakukan dalam es krim sehat dari ekstrak kayu bajakah memiliki keunggulan yang relatif dan sesuai dengan nilai serta kebiasaan masyaraka Indonesia yang menyukai es krim dengan kandungan yang menyehatkan

Bawang tiwai (Eleutherine bulbosa (Mill) Urb)a plant that originated from Kalimantan. This plant is traditionally used as a medicinal plant in the community. Bawang tiwai have bioactive compounds such as alkaloids, flavonoids, saponins which act as antioxidants. In addition bawang tiwai, turmeric (Curcuma domestica Val.)is a traditional medicinal plant used for seasoning and is a medicinal plant as antimicrobial, antioxidant, anti-tumor and anti-inflammatory. The aim of the research is to measure the antioxidant activity of the combination of extracts of bawang tiwai(Eleutherine bulbosa (Mill) Urb)and Turmeric (Curcuma domestica Val.). Antioxidant activity test used the DPPH (1,1-Diphenyl-2-picryl Hidrazil) measured absorption at a wavelength of 517 nm. Antioxidant activity was assessed based on% inhibition (IC50) which is the concentration of the sample solution is needed to reduce free radicals by 50%. The results obtained by measuring the antioxidant activity fromcombination extracts of IC50 was 185,118 ppm respectively.

Abstract: Malaria remains a major public health problem in most tropical and subtropical countries, including Indonesia. Severe malaria has a high mortality rate despite treatment with effective antimalarial drug. Pro-inflammatory cytokines such as Tumor Necrosis Factor-alfa (TNF-α) is raised in severe malaria. In South Kalimantan, the kelakai (Stenochlaena palustris (Burm.f) Bedd) has few uses for treat fever and infectious diseases. It contains bioactive substances, such as flavonoids, steroids, and alkaloids which have been reported to exert multiple biological effects, including anti-inflammatory action. The aim of this study is to find out the potential of kelakai extract (KE) againts TNF-α level in BALB/c mice infected P. berghei ANKA. The research is true experimental study, Posttest-only with Control Group Design. Teatment groups were devided into 4 groups treated with 10 mg/kg BW, 100 mg/kg BW of KE, and 36,4 mg/kg BW artesunate orally (positive control), 3 hours post infection and when parasitemia reached 15-20%. Negative controls were without KE treatment and P. berghei infection. Treatment were given for four days. Blood was collected 24 hours after the last treatment. Plasma TNF-α level were measured by sandwich ELISA. Data was analyzed by using Kruskal-Wallis Test, confidence rate at 95%. There was a significant different between treatment groups, where p = 0,000 (p < 0,05). KE potential to inhibit TNF-α production in Pb3K100A- group (p = 0,047).Keywords : Malaria, TNF-α, Stenochlaena palustris Abstrak: Malaria masih menjadi masalah kesehatan utama pada sebagian besar negara tropis dan subtropis, termasuk Indonesia. Malaria berat menyebabkan angka kematian yang tinggi meskipun telah mendapat obat anti malaria yang efektif. Sitokin pro-inflamasi seperti TNF-α meningkat pada malaria berat. Di Kalimantan Selatan, tanaman kelakai digunakan untuk mengobati demam dan penyakit infeksi. Kelakai mengandung senyawa-senyawa bioaktif antara lain flavonoid, steroid, dan alkaloid yang dilaporkan banyak memiliki efek biologis, termasuk aktivitas anti-inflamasi. Tujuan penelitian ini adalah untuk mengetahui potensi ekstrak kelakai terhadap kadar TNF-α pada mencit BALB/c yang diinfeksi P. berghei ANKA. Penelitian ini merupakan studi eksperimental murni dengan Posttest-only with Control Group Design. Kelompok perlakuan dibagi menjadi 4 yaitu kelompok yang mendapat ekstrak kelakai per oral 10 mg/kg BB, 100 mg/kg BB, artesunat 36,4 mg/kg BB (kontrol positif) 3 jam setelah infeksi dan pada saat parasitemia mencapai 15-20%. Kontrol negatif tidak mendapat ekstrak kelakai, artesunat, dan infeksi parasit. Perlakuan diberikan selama 4 hari. Sampel darah diambil 24 jam setelah perlakuan terakhir. Kadar TNF-α diukur dengan ELISA metode sandwich. Data dianalisa dengan Uji Kruskal-Wallis, dengan tingkat kepercayaan 95%. Terdapat perbedaan bermakna antar kelompok perlakuan, nilai p = 0,000 (p<0,05). Ekstrak kelakai berpotensi menghambat produksi TNF-α pada kelompok Pb3K100A- (p = 0,047). Kata-kata kunci : Malaria, TNF-α, Stenochlaena palustris

The Kelian gold deposit, located 250 km west of the provincial capital of Samarinda, East Kalimantan, is Indonesia's principal gold producer. The deposit is an intrusive-related low sulphidation system, situated within the Central Kalimantan Continental Arc, which consists of andesitic to rhyolitic volcanics and intrusives of Miocene age. Hydrothermal activity produced extensive brecciation, porphyry- to epithermal-style alteration and gold and base metals mineralisation. The nature of genetic relations is the main aspect of this study and is approached through the geochemical evolution of the calc-alkaline suites in relation to the metallic mineralisation. Geochemical evolution in the Miocence calc-alkaline suites from the Kalimantan volcanic arc exhibit two distinctive trends of magmatic differentiation The first trend is defined by a series of "productive" igneous suites such as Kelian, Muyup and Ritan, and is a "typical" calc-alkaline series characterised by low Mg, moderate K, relatively high Ti and Al and depletion in Cr and Sc. The second trend is defined by the chemical variations of the Magerang-Imang and Nakan suites which have remarkably high concentrations of MgO. Major and trace element geochemistry of the high Mg andesites from MagerangImang and Nakan is comparable with that of low-Ca type-2 boninites. The Kelian Igneous Complex is characterised by positive Zr and Hf anomalies in the trace element patterns which is uncommon for calc-alkaline subduction zone magmas. The chemical diversity in the Magerang-Imang and Nakan suite might have been generated by a combined wallrock assimilation and fractional crystallisation process involving a parental basaltic magma and a Zr-rich cumulate. It is suggested that the Magerang-lmang and Nakan high Mg andesites were fed by magma chambers that formed deep in the crust, and were emplaced into pre-existing intrusions of felsic composition that formed as part of the Kelian Igneous Complex cycle. The shallow level stocks at Magerang-1.mang and Nakan were generated by intrusions that melted the walls and roofs of related, but pre-existing intrusions, and extracted abundant xenocrystic zircons during the assimilation process. This study represents the first Platinum Group Element data for a fractionated suite of calc-alkaline andesite. The technique developed in this study represents a breakthrough in our ability to monitor important ore elements in felsic igneous system. The PGE distribution patterns in the Magerang-lmang hornblende andesite are subparallel to each other over a range of concentrations that vary by about a factor of 20. All the Magerang-lmang samples are depleted in Ru, Ir and Os concentrations relative to Re, Pd, Pt and Rh concentrations and have Pd/Ir values of 15 to 54 and Ru/Ir - 1. The PGE concentrations decrease with increasing Si02, showing that they are depleted by fractional crystallisation. Gold is depleted by an order of magnitude and relative to Re and Pd. The low concentration of gold in the igneous rocks associated with the Kelian gold deposit is unexpected. Most metal deposits are found in association with rocks that are already enriched in the metal of interest. It is therefore surprising to find a major gold deposit in host rocks that are depleted in Au. It is also interesting that Au and PGE ratios change little during fractionation. This is surprising because it implies either that the partition coefficients for the PGEs into the sulphides are similar, which seems unlikely, or that Au and the PGEs are not being depleted by simple equilibriwn fractional crystallisation of sulphide. Alternatively, the gold and PGE fractionation are due to the assimilation of crustal material. This appears to be the most plausible process for the gradual depletion of Au and all of the PGE at Kellan. It is suggested that simple dilution with crustal material that contains no Au or PGE is the most likely process that will decrease the abundance of all of the PGE equally. Zircon U-Th-Pb isotope dates were determined in situ using excimer laser ablation ICP-MS. The two different bodies of the Magerang hornblende andesite yielded a single age of 19.38 ± 0.12 Ma and 19.62 ± 0.21 Ma, while the Nakan andesite gave an age of 20.01± 0.15 Ma. The Central Andesite porphyry at Kelian gave 3 populations of U-Pb zircon dates: 21.2 ± 0.32 Ma, 20.5 ± 0.12 Ma and 19.7 ± 0.12 Ma. The youngest date (19.7 Ma) is interpreted as the emplacement age and the two older zircon populations represent the age of inherited zircons coming from the previous thermal event that affected the source region of the andesite. The U-Pb zircon dating for the Runcing Rhyolite porphyry also yielded 3 distinctive date populations: the youngest date of zircon population (19.3 ± 0.1 Ma) is interpreted as the emplacement age and the other two populations (20.0 ± 0.2 Ma and 20.8 ± 0.1 Ma) represent the ages of inherited zircons. The emplacement age of the Magerang-Imang andesite implies that the highsulphidation Cu-Au mineralisation at Magerang is younger than the low-sulphidation Au deposit at Kelian. The Kelian and Magerang andesites have a relatively short interval of emplacement ages suggesting that the duration of magmatism and related epitbermal mineralisation in the larger Kelian region was between 0.5 - 1 Ma. During this period, the magmatic-hydrothermal system has produced 2 distinctive types of epithermal mineralisation: firstly, low-sulphidation Au deposit at Kelian and secondly highsulphidation Cu-Au mineralisation at Magerang-Imang. Detrital zircons from the Mahakam and Kelian rivers were dated to obtain the overall duration of volcanism in the region. These zircons are dominated by Pliocene, Miocene, Cretaceous, Triassic, Permian and Carboniferous zircons. The youngest detrital zircon from the Kelian river gave an age of 1.7 ± 0.1 Ma and the oldest one gave an age of 373 Ma. Within the Tertiary zircon population, there are age spectra peaks at Pliocene (from 1.7 Ma to 2.8 Ma) and Miocene (from 15.8 Ma to 21.7 Ma). The Cretaceous zircon population ranges from 67 .6 to 126.3 Ma and peaks at l 05 Ma. The gold mineralisation at Kelian occurs toward the end of the Miocene volcanism and took place locally within the Kelian region as this Miocene volcanism is not recorded in the zircon component from the larger Mahakam river. The two large inheritance populations in both the Central Andesite and Runcing Rhyolite lie within the time range of the Kelian igneous complex as defined by the KeJian River detrital zircons. They must be derived from crustal intrusions that formed as part of the Kelian cycle. It is suggested that both the Kelian Andesite and Runcing Rhyolite were fed by 2 magma chambers that formed deep in the crust, each of which were long lived. The magma chambers that fed the Kelian Andesite and Runcing Rhyolite were emplaced into pre-existing intrusions of similar composition that formed as part of the Kelian igneous complex. The abundance of xenocrystic zircons in both units suggests that these earlier intrusions were still hot, or perhaps even partially molten, at the time of magma emplacement. That is the shallow level stocks and diatremes at Kelian were fed by nested, cannibalistic intrusions deep in the crust that melted the walls and roofs of related, but pre-existing intrusions, and inherited abundant xenocrystic zircons in the process. Both the Kelian Andesite and the Runcing Rhyolite have two populations of inherited zircons, which indicate that the pre-existing intrusions formed in two distinct episodes, 0.7 to 0.8 m.y. apart. The difference between the emplacement age and the age of the oldest of the inherited zircon populations shows that this cannibalistic activity took place over 1.5 m.y. The interval of magmatic activity in these chambers corresponds to the period of peak activity in the Kelian igneous complex as defined by the detrital zircons.