Journal articles on the topic 'Jaw muscle pain'

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1

Sae-Lee, Daraporn, Kamal Wanigaratne, Terry Whittle, Christopher C. Peck, and Greg M. Murray. "A method for studying jaw muscle activity during standardized jaw movements under experimental jaw muscle pain." Journal of Neuroscience Methods 157, no. 2 (October 2006): 285–93. http://dx.doi.org/10.1016/j.jneumeth.2006.05.005.

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2

Akhter, Rahena, Janet Benson, Peter Svensson, Michael K. Nicholas, Christopher C. Peck, and Greg M. Murray. "Experimental Jaw Muscle Pain Increases Pain Scores and Jaw Movement Variability in Higher Pain Catastrophizers." Journal of Oral & Facial Pain and Headache 28, no. 3 (June 2014): 191–204. http://dx.doi.org/10.11607/ofph.1211.

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3

Clark, G. T., R. W. Jow, and J. J. Lee. "Jaw Pain and Stiffness Levels After Repeated Maximum Voluntary Clenching." Journal of Dental Research 68, no. 1 (January 1989): 69–71. http://dx.doi.org/10.1177/00220345890680011101.

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Ten normal male volunteers performed six maximum voluntary isometric jaw-closing muscle contractions within an 80-minute experimental period. Each individual contraction was sustained until maximum pain tolerance was reached. Before and one, two, three, and seven days after the experiment, the following measures were made: (1) superficial masseter and anterior temporalis muscle tenderness (pain threshold), (2) jaw movement (opening and lateral excursion), and (3) current pain level for the right and left sides of the jaw. In this study, measures of current jaw pain, muscle pain threshold, maximum active opening, and maximum lateral excursions showed no significant post-experimental changes. These results challenge the idea that sustained isometric clenching in healthy male subjects could be used as a model for chronic or even subacute muscle pain, as has been suggested by previous investigators.
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4

Koutris, M., F. Lobbezoo, M. Naeije, K. Wang, P. Svensson, L. Arendt-Nielsen, and D. Farina. "Effects of Intense Chewing Exercises on the Masticatory Sensory-Motor System." Journal of Dental Research 88, no. 7 (July 2009): 658–62. http://dx.doi.org/10.1177/0022034509338573.

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Nociceptive substances, injected into the masseter muscle, induce pain and facilitate the jaw-stretch reflex. It is hypothesized that intense chewing would provoke similar effects. Fourteen men performed 20 bouts of 5-minute chewing. After each bout, 20 min and 24 hrs after the exercise, muscle fatigue and pain scores and the normalized reflex amplitude from the left masseter muscle were recorded. Before, 20 min, and 24 hrs after the exercise, signs of temporomandibular disorders and pressure-pain thresholds of the masticatory muscles were also recorded. Fatigue and pain scores had increased during the exercise (P < 0.001), but the reflex amplitude did not (P = 0.123). Twenty minutes after the exercises, 12 participants showed signs of myofascial pain or arthralgia. Pressure-pain thresholds were decreased after 20 min (P = 0.009) and 24 hrs (P = 0.049). Intense chewing can induce fatigue, pain, and decreased pressure-pain thresholds in the masticatory muscles, without concomitant changes in the jaw-stretch reflex amplitude.
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5

D’Attilio, Michele, Beatrice Di Carlo, Francesco Caroccia, Francesco Moscagiuri, Debora Mariarita d’Angelo, Francesco Chiarelli, Felice Festa, and Luciana Breda. "Clinical and Instrumental TMJ Evaluation in Children and Adolescents with Juvenile Idiopathic Arthritis: A Case—Control Study." Applied Sciences 11, no. 12 (June 10, 2021): 5380. http://dx.doi.org/10.3390/app11125380.

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To investigate temporomandibular joint (TMJ) involvement signs such as muscle pain, the ratio of masseter and temporal muscle activity, mouth opening width and jaw deviation during mouth opening in children and adolescents with juvenile idiopathic arthritis (JIA), a group of 32 subjects with JIA and a control group of 32 healthy subjects were evaluated. Data were collected clinically by muscle palpation (masseters, anterior temporalis and sternocleidomastoids) and instrumental analysis (electromyography and kinesiography). Higher pain was registered in the masseter and sternocleidomastoid muscles on both sides and in the right anterior temporalis in the JIA group compared to the control group (p < 0.05). Electromyography showed no statistically significant difference in the frequency of the pathological ratio of masseter and temporal muscle activity (MM/TA < 1) both in the JIA group and in the control group. Kinesiography showed a statistically significant difference in mouth opening width and jaw deviation during mouth opening between the groups (p < 0.05): JIA subjects showed lower mouth opening values and wider deviation on mouth opening; 29 out of 32 JIA subjects showed jaw deviation towards the right side. JIA affects the TMJ, causing myalgia in the head and neck muscles, a reduction in mouth opening width and an increase in jaw deviation during mouth opening.
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6

Yachida, W., E. E. Castrillon, L. Baad-Hansen, R. Jensen, T. Arima, A. Tomonaga, N. Ohata, and P. Svensson. "Craniofacial Pain and Jaw-muscle Activity during Sleep." Journal of Dental Research 91, no. 6 (April 18, 2012): 562–67. http://dx.doi.org/10.1177/0022034512446340.

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7

Stohler, Christian S., Xin Zhang, and James P. Lund. "The effect of experimental jaw muscle pain on postural muscle activity." Pain 66, no. 2 (August 1996): 215–21. http://dx.doi.org/10.1016/0304-3959(96)03026-6.

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8

Wang, K., B. J. Sessle, P. Svensson, and L. Arendt-Nielsen. "Glutamate evoked neck and jaw muscle pain facilitate the human jaw stretch reflex." Clinical Neurophysiology 115, no. 6 (June 2004): 1288–95. http://dx.doi.org/10.1016/j.clinph.2004.01.006.

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9

MOBILIO, N., and S. CATAPANO. "Effect of experimental jaw muscle pain on occlusal contacts." Journal of Oral Rehabilitation 38, no. 6 (November 5, 2010): 404–9. http://dx.doi.org/10.1111/j.1365-2842.2010.02173.x.

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10

Wiesinger, B., B. Häggman-Henrikson, F. Hellström, and A. Wänman. "Experimental masseter muscle pain alters jaw-neck motor strategy." European Journal of Pain 17, no. 7 (December 14, 2012): 995–1004. http://dx.doi.org/10.1002/j.1532-2149.2012.00263.x.

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11

Minami, I., R. Akhter, I. Albersen, C. Burger, T. Whittle, F. Lobbezoo, C. C. Peck, and G. M. Murray. "Masseter Motor Unit Recruitment is Altered in Experimental Jaw Muscle Pain." Journal of Dental Research 92, no. 2 (December 14, 2012): 143–48. http://dx.doi.org/10.1177/0022034512470832.

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Some management strategies for chronic orofacial pain are influenced by models ( e.g., Vicious Cycle Theory, Pain Adaptation Model) proposing either excitation or inhibition within a painful muscle. The aim of this study was to determine if experimental painful stimulation of the masseter muscle resulted in only increases or only decreases in masseter activity. Recordings of single-motor-unit (SMU, basic functional unit of muscle) activity were made from the right masseters of 10 asymptomatic participants during biting trials at the same force level and direction under infusion into the masseter of isotonic saline (no-pain condition), and in another block of biting trials on the same day, with 5% hypertonic saline (pain condition). Of the 36 SMUs studied, 2 SMUs exhibited a significant ( p < 0.05) increase, 5 a significant decrease, and 14 no significant change in firing rate during pain. Five units were present only during the no-pain block and 10 units during the pain block only. The findings suggest that, rather than only excitation or only inhibition within a painful muscle, a re-organization of activity occurs, with increases and decreases occurring within the painful muscle. This suggests the need to re-assess management strategies based on models that propose uniform effects of pain on motor activity.
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12

Peck, CC, GM Murray, and TM Gerzina. "How does pain affect jaw muscle activity? The Integrated Pain Adaptation Model." Australian Dental Journal 53, no. 3 (September 2008): 201–7. http://dx.doi.org/10.1111/j.1834-7819.2008.00050.x.

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13

Sherman, Richard A. "Relationships between jaw pain and jaw muscle contraction level: Underlying factors and treatment effectiveness." Journal of Prosthetic Dentistry 54, no. 1 (July 1985): 114–18. http://dx.doi.org/10.1016/s0022-3913(85)80084-6.

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14

Inamoto, Kyoko, Greg M. Murray, and Terry Whittle. "Effect of a brief episode of experimental muscle pain on jaw movement and jaw-muscle activity during chewing." European Journal of Oral Sciences 125, no. 1 (December 22, 2016): 34–43. http://dx.doi.org/10.1111/eos.12321.

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15

Arioğlu, Ender Ege, and Rory Molloy. "A comparative approach to treatment methods for myofacial pain and internal derangement of the temporomandibular joint." Morecambe Bay Medical Journal 8, no. 1 (August 1, 2018): 16–23. http://dx.doi.org/10.48037/mbmj.v8i1.52.

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The temporomandibular joint (TMJ) is the site of articulation between the mandibular fossa of the temporal bone and condylar head of the mandible. The TMJ is a synovial joint that has a cartilaginous disc between two articular surfaces. It can perform rotation and translation. A group of muscles (primarily masseter, temporalis and pterygoids) and ligaments are involved in jaw movement. The group of disorders that encompasses dysfunction of these structures is called “temporomandibular disorders (TMD)”. This research primarily focuses on myofacial pain, dysfunction and internal derangement of the TMJ (anterior disc displacement (ADD) with and without reduction). Treatments include conservative and invasive interventions. Conservative treatment consists of behavioural/psychosocial therapy, physiotherapy, pain management, occlusal splint therapy, low-level laser therapy and transcutaneous electric nerve stimulation therapy. Conservative treatment provides very effective results for pain relief and signifi cant improvement of jaw function, however follow-up periods in studies were short-term (not more than three months). Continuous improvement was observed in occlusal splint therapy as it leads to sustained behavioural change, helpful in alleviating pain by reducing stress put on the masticatory muscles and correcting jaw function. Exercise and physiotherapy have also resulted in considerable pain reduction and restoration of jaw function. Evidence showed that botulinum-toxin type A provided an immediate alleviation of pain effective for 3 months, however decreased maximal incisal opening as its mechanism of action is inhibiting muscle activity.
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16

Lavigne, G. J., T. Kato, A. Kolta, and B. J. Sessle. "Neurobiological Mechanisms Involved in Sleep Bruxism." Critical Reviews in Oral Biology & Medicine 14, no. 1 (January 2003): 30–46. http://dx.doi.org/10.1177/154411130301400104.

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Sleep bruxism (SB) is reported by 8% of the adult population and is mainly associated with rhythmic masticatory muscle activity (RMMA) characterized by repetitive jaw muscle contractions (3 bursts or more at a frequency of 1 Hz). The consequences of SB may include tooth destruction, jaw pain, headaches, or the limitation of mandibular movement, as well as tooth-grinding sounds that disrupt the sleep of bed partners. SB is probably an extreme manifestation of a masticatory muscle activity occurring during the sleep of most normal subjects, since RMMA is observed in 60% of normal sleepers in the absence of grinding sounds. The pathophysiology of SB is becoming clearer, and there is an abundance of evidence outlining the neurophysiology and neurochemistry of rhythmic jaw movements (RJM) in relation to chewing, swallowing, and breathing. The sleep literature provides much evidence describing the mechanisms involved in the reduction of muscle tone, from sleep onset to the atonia that characterizes rapid eye movement (REM) sleep. Several brainstem structures ( e.g., reticular pontis oralis, pontis caudalis, parvocellularis) and neurochemicals ( e.g., serotonin, dopamine, gamma aminobutyric acid [GABA], noradrenaline) are involved in both the genesis of RJM and the modulation of muscle tone during sleep. It remains unknown why a high percentage of normal subjects present RMMA during sleep and why this activity is three times more frequent and higher in amplitude in SB patients. It is also unclear why RMMA during sleep is characterized by co-activation of both jaw-opening and jaw-closing muscles instead of the alternating jaw-opening and jaw-closing muscle activity pattern typical of chewing. The final section of this review proposes that RMMA during sleep has a role in lubricating the upper alimentary tract and increasing airway patency. The review concludes with an outline of questions for future research.
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17

Hannam, Alan G., and Anne S. McMillan. "Internal Organization in the Human Jaw Muscles." Critical Reviews in Oral Biology & Medicine 5, no. 1 (January 1994): 55–89. http://dx.doi.org/10.1177/10454411940050010301.

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The human jaw muscles are essential to mastication and play an important part in craniofacial growth. They contribute to dental and articular forces, deform the mandible, and, like other tissues, are subject to disorders, often manifested as pain. The literature describes how their contraction is controlled by the nervous system, and how their general structure and function contribute to craniofacial biology, but there has been little appraisal of their internal organization. Most of these muscles are not simple; they are multipennate, complexly layered, and divided by aponeuroses. This arrangement provides substantial means for differential contraction. In many ways, jaw muscle fibers are intrinsically dissimilar from those found in other skeletal muscles, because they are arranged in homogeneous clusters and generally reveal type I or type II histochemical profiles. Most are type I and are distributed preferentially in the anterior and deeper parts of the jaw closers. Additionally, most motor unit (MU) territories are smaller than those in the limbs. There is circumstantial evidence for intramuscular partitioning based in part on innervation by primary muscle nerve branches. During normal function, MU recruitment and the rate coding of MU firing in human jaw muscles follow the general principles established for the limbs, but even here they differ in important respects. Jaw muscle MUs do not have stable force recruitment thresholds and seem to rely more on rate coding than on sequential unit recruitment to grade the amplitude of muscle contraction. Unlike those in the limbs, their twitch tensions correlate weakly with MU fatiguability and contraction speed, probably because there are so few slow, fatigue-resistant MUs in the jaw muscles. Moreover, the type I fibers that are present in such large numbers do not contract as slowly as normally expected. To complicate matters, estimation of jaw MU twitch tensions is extremely difficult, because it is affected by the location used to measure the twitch, the background firing rate, muscle coactivation, and regional, intramuscular mechanics. Finally, there have been very few systematic studies of jaw MU reflex behavior. The most recent have concentrated on exteroceptive suppression and suggest that MU inhibition following intra- and perioral stimulation depends on the location of the MU, its background firing rate, the timing of the stimulus, and the task used to drive the unit. Task dependency is a common feature of human jaw MU behavior, reflecting interaction between peripheral sensory information from orofacial and muscle afferents and corticobulbar drive. In summary, several lines of evidence, including intramuscular structure, the disposition and physiological behavior of the intrinsic MUs, strongly suggest that human jaw muscles are uniquely organized internally. Both structural and functional attributes need to be incorporated into a hypothetical model of each muscle in order to explain how it produces local tensions and displacements during normal use and the circumstances under which any disordered biomechanical events might be induced in it.
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18

Amhamed, M., T. Whittle, T. Maulina, J. Gal, R. Akhter, and G. M. Murray. "Effect of experimental anterior temporalis muscle pain on jaw movements." Journal of Oral Rehabilitation 43, no. 12 (November 1, 2016): 889–99. http://dx.doi.org/10.1111/joor.12449.

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19

Wang, K., T. Arima, L. Arendt-Nielsen, and P. Svensson. "EMG-force relationships are influenced by experimental jaw-muscle pain." Journal of Oral Rehabilitation 27, no. 5 (May 2000): 394–402. http://dx.doi.org/10.1046/j.1365-2842.2000.00617.x.

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20

Obrez, Ales, and Christian S. Stohler. "Jaw muscle pain and its effect on gothic arch tracings." Journal of Prosthetic Dentistry 75, no. 4 (April 1996): 393–98. http://dx.doi.org/10.1016/s0022-3913(96)90031-1.

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21

Castrillon, Eduardo E., Brian E. Cairns, Malin Ernberg, Kelun Wang, Barry Sessle, Lars Arendt-Nielsen, and Peter Svensson. "Glutamate-evoked jaw muscle pain as a model of persistent myofascial TMD pain?" Archives of Oral Biology 53, no. 7 (July 2008): 666–76. http://dx.doi.org/10.1016/j.archoralbio.2008.01.008.

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22

Sae-Lee, Daraporn, Terry Whittle, Anna R. C. Forte, Christopher C. Peck, Karen Byth, Barry J. Sessle, and Greg M. Murray. "Effects of experimental pain on jaw muscle activity during goal-directed jaw movements in humans." Experimental Brain Research 189, no. 4 (June 13, 2008): 451–62. http://dx.doi.org/10.1007/s00221-008-1439-0.

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23

Shimada, A., L. Baad-Hansen, and P. Svensson. "Effect of experimental jaw muscle pain on bite force during mastication." Scandinavian Journal of Pain 3, no. 3 (July 1, 2012): 190–91. http://dx.doi.org/10.1016/j.sjpain.2012.05.047.

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AbstractBackground/aimsMuscular pain often impairs masticatory function in Temporomandibular disorder patients. The specific aim of this study was to investigate how the bite force during mastication is influenced by experimental muscle pain caused by infusion of glutamate into the masseter muscle.Methods12 healthy adults participated, after providing informed consent. Customized metal frames of the intraoral bite force sensor were manufactured for all subjects, and placed on their preferred chewing side. To induce experimental pain, a sterile solution of glutamate (0.5 M) was infused into the posterior part of the masseter muscle. Isotonic saline (0.9%) was infused as a control (randomized, cross-over design). During chewing three different kinds of test food (two different size carrots and gummy), bite force, electromyographic (EMG) activity of bilateral masseter muscle and anterior temporalis muscle were recorded. The first and last five masticatory cycles were used for analyses. The outcome parameters were as follows; Visual Analog Scale (VAS) for pain, impulse and duration from the bite force signal, duration and amplitude of EMG. Three-way ANOVAs with food (3 levels), sessions (5 levels: baseline, during glutamate, baseline 2, during isotonic saline, follow-up), cycles (2 × 5 levels) were carried out.ResultsGlutamate caused moderate levels of pain (mean VAS: 2.4 ± 0.9) whereas isotonic saline only caused low levels of pain (Mean VAS: 0.7 ± 0.5). The ANOVA of impulse data, as well as most EMG data, demonstrated a significant effect of session. Post hoc tests showed significantly higher impulse values of both the first and last five cycles in the glutamate session compared to baseline whereas the EMG activity was significantly decreased (P < 0.05).ConclusionSurprisingly, experimental pain induced by glutamate increased the bite force during mastication coupled with a decrease in EMG activity. This indicates a major reorganization of the motor control during painful mastication.
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Van Der Spek, A. F. L., P. I. Reynolds, J. A. Ashton-Miller, C. S. Stohler, and M. A. Schork. "Differing Effect of Agonist and Antagonist Muscle Relaxants on Cat Jaw Muscles." Anesthesia & Analgesia 69, no. 1 (July 1989): 76???80. http://dx.doi.org/10.1213/00000539-198907000-00014.

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25

Sonmezocak, Temel, and Serkan Kurt. "Detection of EMG Signals by Neural Networks Using Autoregression and Wavelet Entropy for Bruxism Diagnosis." Elektronika ir Elektrotechnika 27, no. 2 (April 29, 2021): 11–21. http://dx.doi.org/10.5755/j02.eie.28838.

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Bruxism is known as the rhythmical clenching of the lower jaw (mandibular) by the contraction of the masticatory muscles and parafunctional grinding of the teeth. It affects patients’ quality of life adversely due to tooth wear, pain, and fatigue in the jaw muscles. Recently, effective diagnosis methods that use electromyography, electrocardiography, and electroencephalography have been developed for bruxism. However, these methods are not economical since they require specialization and can be performed in clinical conditions. Although using surface electromyography signals alone is an economical solution, it is difficult to identify fatigue and parafunctional movements of the jaw muscles via electromyography signals due to peripheral effects. In this study, to achieve an accurate diagnosis of bruxism economically with only electromyography measurements, a new approach based on Autoregression and Shannon Entropies of Discrete Wavelet Transform Energy Spectra to identify jaw muscle activities and fatigue conditions is proposed. By using Artificial Neural Networks in the proposed model, bruxism activities can be detected most accurately.
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Svensson, Peter, Kelun Wang, and Lars Arendt-Nielsen. "Effect of muscle relaxants on experimental jaw-muscle pain and jaw-stretch reflexes: a double-blind and placebo-controlled trial." European Journal of Pain 7, no. 5 (October 2003): 449–56. http://dx.doi.org/10.1016/s1090-3801(03)00013-2.

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27

Tello, Mónica, Mirian Pizarro, Doris Calderón, and Deniss Calderón. "Prevalence of temporomandibular disorders in a sample of Ecuadorian elderly." International Journal of Medical and Surgical Sciences 5, no. 2 (November 26, 2018): 67–70. http://dx.doi.org/10.32457/ijmss.2018.017.

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Abstract: The aim of this study was to determine the prevalence of temporomandibular disorders (TMDs) in a sample of Ecuadorian older adults in 2018. This is a cross-sectional study, which was conducted with a sample of 143 older adults of both sexes of the “Senderito de Amor” Elderly Home. The evaluation instrument was the Helkimo index, with the following parameters: presence of muscle pain, difficulty in opening and closing movement, joint pain, joint noises, limitation of mouth opening, limitation of lateral movement, and propulsion and deviation of the jaw. Overall, 88.8% of the population had TMDs, with 85.7% in the group of 60–70 years, 81.8% in the group of 71–80 years, 96.7% in those over 80 years, and 81.0% men and 92.1% women. Statistically significant differences were found by age (p = 0.035), but not by sex (p = 0.055). The most frequent signs and symptoms were joint noise (82.5%), followed by deviation of the jaw during opening (60.1%), reduction of the mouth opening (41.3%), difficulty of opening movements and closure (35.0%), reduction in movements of laterality and propulsion (29.4%), joint and muscle pain (24.5%), muscle pain (18.9%), and joint pain (16.8%). In conclusion, there is a high prevalence of temporomandibular disorders in older adults, and the most frequent signs and symptoms were joint sounds and deviation of the jaw during the mouth opening.
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Svensson, Peter, Lars Houe, and Lars Arendt-Nielsen. "Bilateral experimental muscle pain changes electromyographic activity of human jaw-closing muscles during mastication." Experimental Brain Research 116, no. 1 (August 18, 1997): 182–85. http://dx.doi.org/10.1007/pl00005738.

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Capra, Norman F., and Jin Y. Ro. "Experimental muscle pain produces central modulation of proprioceptive signals arising from jaw muscle spindles." Pain 86, no. 1 (May 2000): 151–62. http://dx.doi.org/10.1016/s0304-3959(00)00231-1.

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Cairns, Brian E., James W. Hu, Lars Arendt-Nielsen, Barry J. Sessle, and Peter Svensson. "Sex-Related Differences in Human Pain and Rat Afferent Discharge Evoked by Injection of Glutamate Into the Masseter Muscle." Journal of Neurophysiology 86, no. 2 (August 1, 2001): 782–91. http://dx.doi.org/10.1152/jn.2001.86.2.782.

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Animal studies have suggested that tissue injury–related increased levels of glutamate may be involved in peripheral nociceptive mechanisms in deep craniofacial tissues. Indeed, injection of glutamate (0.1–1 M, 10 μl) into the temporomandibular region evokes reflex jaw muscle responses through activation of peripheral excitatory amino acid receptors. It has recently been found that this glutamate-evoked reflex muscle activity is significantly greater in female than male rats. However, it is not known whether peripheral administration of glutamate, in the same concentrations that evoke jaw muscle activity in rats, causes pain in humans or activates deep craniofacial nociceptive afferents. Therefore we examined whether injection of glutamate into the masseter muscle induces pain in male and female volunteers and, since masseter afferent recordings were not feasible in humans, whether glutamate excites putative nociceptive afferents supplying the masseter muscle of male and female rats. Injection of glutamate (0.5 M or 1.0 M, 0.2 ml) into the masseter muscle of both men and women caused significantly higher levels of peak pain, duration of pain, and overall pain than injection of isotonic saline (0.2 ml). In addition, glutamate-evoked peak and overall muscle pain in women was significantly greater than in men. In rats of both sexes, glutamate (10 μl, 0.5 M) evoked activity in a subpopulation of masseter muscle afferents ( n = 36) that projected to the subnucleus caudalis, an important relay of noxious input from the craniofacial region. The largest responses to glutamate were recorded in muscle afferents with the slowest conduction velocities (2.5–5 m/s). Further, glutamate-evoked masseter muscle afferent activity was significantly greater in female than in male rats. These results indicate that glutamate injection into the masseter muscle evokes pain responses that are greater in women than men and that one possible mechanism for this difference may be a greater sensitivity to glutamate of masseter muscle afferents in females. These sex-related differences in acute experimental masseter muscle pain are particularly interesting given the higher prevalence of many chronic muscle pain conditions in women.
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Didenko, Natalya, Vladimir Gazinskiy, Oleg Nikitin, Evgeniy Mokrenko, Igor Kostritsky, Ivan Goncharov, Maria Suslikova, et al. "On Muscular Factor Question in the Correction of Transversal Incisor Occlusion." International Journal of Biomedicine 12, no. 1 (March 10, 2022): 147–50. http://dx.doi.org/10.21103/article12(1)_oa17.

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The aim of our study was to evaluate the role of the muscle factor and the effectiveness of manual treatment of masticatory muscle dysfunction in patients with transversal incisor occlusion (TIO). Methods and Results: We examined and treated 35 patients aged 18-25 years with clinical signs of TIO in the clinic of orthopedic dentistry. Diagnostic methods for TIO included an interview, face and oral cavity examination, and clinical functional tests. Occlusion was assessed using anthropometric measurements and examination of plaster jaw models in an articulator for additional diagnostics of the dental factor; a radiological method (jaw orthopantomography with the inclusion of articular joints) was also used for the articular factor diagnostics and examination of masticatory muscles and neck muscles. The treatment methods included manual treatment of masticatory muscle dysfunction: "myofascial trigger point release technique," "stretching-push," and "post-isometric relaxation." All patients' complaints were mainly confined to improper occlusion of the front teeth, namely, a misalignment of the centerline between the upper and lower anterior teeth. Moreover, 71.4% of patients noted intermittent clicking in one or both articular joints of the temporomandibular joint, 42.8% of patients reported pain in the region of one temporomandibular joint, 28.6% of patients noted noise in the ear of the same joint, as well as discomfort while chewing. On external examination, all patients had a slight asymmetry of the lips and cheeks on the habitual chewing side. The apex of the chin was positioned slightly to the side relative to the facial midline. All patients had a disturbed movement trajectory of the lower jaw. During mouth opening, the lower jaw trajectory changed relative to the facial midline: at first, it was straight, for a very short period, and then it deviated sideways, after which it returned to the center. There was a misalignment of the central line of the lower dentition relative to the midline of the face in the anterior region. The radiological picture showed signs of articular joint dysfunction: difference in the size of the articular gaps on the right and left sides. After a single session of manual treatment of masticatory muscles, all patients noted that the improper occlusion of the front teeth was corrected, pain and clicking sensations in the TMJ disappeared in 42.8% of patients, and pain disappeared in the area of one joint, along with noise in the ears and chewing discomfort. Headache in the parietal and temporal areas disappeared. The trajectory of lower jaw movements during mouth opening normalized in all patients after the performed manual treatment. Conclusion: We can conclude that when diagnosing and treating occlusal disorders, it is necessary to pay attention not only to the position of the teeth and the TMJ elements, but also to the muscular factor – the condition of the masticatory muscles. Special attention should be paid to the condition of the lateral wing muscles.
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Kim, Cheul, Ji Rak Kim, and Jin Woo Chung. "Gender Differences in Pressure Pain Thresholds during Sustained Jaw Muscle Contraction." Journal of Oral Medicine and Pain 39, no. 4 (December 30, 2014): 146–51. http://dx.doi.org/10.14476/jomp.2014.39.4.146.

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33

Arima, Taro, Lars Arendt-Nielsen, Shogo Minagi, and Peter Svensson. "Effect of capsaicin-evoked jaw-muscle pain on intramuscular blood-flow." Archives of Oral Biology 54, no. 3 (March 2009): 241–49. http://dx.doi.org/10.1016/j.archoralbio.2008.11.005.

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34

Koyano, Kiyoshi, Youn Joong Kim, and Glenn T. Clark. "Electromyographic signal changes during exercise in human chronic jaw-muscle pain." Archives of Oral Biology 40, no. 3 (March 1995): 221–27. http://dx.doi.org/10.1016/0003-9969(95)98811-c.

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35

Maulina, Tantry, Magda Amhamed, Terry Whittle, John Gal, Rahena Akhter, and Greg Murray. "The Effects of Experimental Temporalis Muscle Pain on Jaw Muscle Electromyographic Activity During Jaw Movements and Relationships with Some Psychological Variables." Journal of Oral & Facial Pain and Headache 32, no. 1 (January 2018): 29–39. http://dx.doi.org/10.11607/ofph.1821.

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Hsieh, Yueh-Ling, Chen-Chia Yang, and Nian-Pu Yang. "Ultra-Low Frequency Transcutaneous Electrical Nerve Stimulation on Pain Modulation in a Rat Model with Myogenous Temporomandibular Dysfunction." International Journal of Molecular Sciences 22, no. 18 (September 14, 2021): 9906. http://dx.doi.org/10.3390/ijms22189906.

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Masticatory myofascial pain (MMP) is one of the most common causes of chronic orofacial pain in patients with temporomandibular disorders. To explore the antinociceptive effects of ultra-low frequency transcutaneous electrical nerve stimulation (ULF-TENS) on alterations of pain-related biochemicals, electrophysiology and jaw-opening movement in an animal model with MMP, a total of 40 rats were randomly and equally assigned to four groups; i.e., animals with MMP receiving either ULF-TENS or sham treatment, as well as those with sham-MMP receiving either ULF-TENS or sham treatment. MMP was induced by electrically stimulated repetitive tetanic contraction of masticatory muscle for 14 days. ULF-TENS was then performed at myofascial trigger points of masticatory muscles for seven days. Measurable outcomes included maximum jaw-opening distance, prevalence of endplate noise (EPN), and immunohistochemistry for substance P (SP) and μ-opiate receptors (MOR) in parabrachial nucleus and c-Fos in rostral ventromedial medulla. There were significant improvements in maximum jaw-opening distance and EPN prevalence after ULF-TENS in animals with MMP. ULF-TENS also significantly reduced SP overexpression, increased MOR expression in parabrachial nucleus, and increased c-Fos expression in rostral ventromedial medulla. ULF-TENS may represent a novel and applicable therapeutic approach for improvement of orofacial pain induced by MMP.
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Carrillo, Ryner Jose C. "Pterygoid Botolinum Toxin Injection." Philippine Journal of Otolaryngology-Head and Neck Surgery 26, no. 1 (June 27, 2011): 55–56. http://dx.doi.org/10.32412/pjohns.v26i1.615.

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Botolinum is a toxic polypeptide produced by the gram-positive anaerobic bacterium Clostridium botulinum that inhibits acetylcholine release from nerve endings, resulting in reduced neuromuscular transmission and local muscle activity, as well as cholinergic mediated parasympathetic activities.1 Its name is derived from the Latin word botulus, meaning sausage, as its toxicity was initially attributed to the oil of spoiled sausages. Of late, botolinum, packaged in various commercial forms such as onabotulinumtoxinA (Botox® type A, Allergan, Irvine, CA), is popularly used in several medical applications such as blepharospasm, hyperhidrosis and strabismus, and most famously in cosmetic surgery, where Botox® injections are used to eliminate and/or smoothen wrinkles. In otolaryngology, common indications for Botox® injections include management of rhytids, cervical dystonia and spasmodic dysphonia. Another interesting application is pterygoid muscle injection. The lateral pterygoid muscles (LPM) pull the condylar head of the jaw forward, resulting in the opening of the jaw or displacement of the mandible anteriorly or towards the contralateral side, whereas the medial pterygoid muscles (MPM) pull the angle of the jaw upward and anteriorly to close or protrude the jaw, respectively. Increased or unequal activity of these muscles relative to other muscles of mastication and temporomandibular joint ligaments may result in asymmetry, malocclusion, temporo-mandibular joint (TMJ) dysfunction or dislocation.2 Indications for pterygoid muscle botox injection include neurogenic TMJ dislocation, recurrent TMJ dislocation, oromandibular dystonia (OMD) particularly LPM dystonia, LPM spasm in condylar fractures, TMJ clicking, bruxism with myofascial pain and stroke-induced trismus.3-20 Several patients with indications for Botox® injection of the pterygoid muscle have been seen by this author, including post cerebro-vascular disease (CVD) dystonia with recurrent TMJ dislocation, bruxism, condylar fracture and oromandibular dystonia, but only the latter had the opportunity to acquire Botox® and the electrode needle (Ambu® Neuroline Inoject 50mm/2” length x 0.50mm/25 Gauge Calibre, Ambu A/S, Denmark) due to cost constraints. We used a Caldwell Sierra Wave® V Electromyography (EMG) Machine with v. 10.0.125 software (Caldwell Laboratories, Inc., Kennewick, WA). The most exciting parts of performing the procedure are the anatomy and process of identifying the muscle with EMG guidance and the immediate results after injection. Electromyography (EMG) – guided botolinum injection can measure muscle activity by recording muscle depolarization or electrical activity. Using cannula needle electrodes with an open lumen, the muscles are identified by their activity during muscle contraction and then injected with Botox® to decrease muscle activity. Anatomically, the LPM is accessible through the mandibular notch which is directly anterior to the condylar head of the mandible. The latter is easily palpable and is anterior to the external auditory canal (Figure 1). Using a needle electrode, the LPM can be identified by opening the jaw or moving the jaw to the contralateral side.2,21 The MPM is less easily targeted because it generally closes the jaw. However, to further decrease anterior displacement of the jaw, both the LPM and the MPM activity can be decreased. The MPM can be targeted transorally by inserting the EMG electrode medial to the jaw and lateral to the pterygomandiular raphe, piercing through the buccinator muscle. Identifying MPM contraction can be done by biting to occlude the upper and lower jaw. With the cheeks retracted and needle inserted, Botox® injection can be done to lower MPM activity. Clinical outcome can be assessed by measuring inter-incisor distance, mandibular deviation and protrusion, decrease in pain, restoration of masticatory function and proper occlusion. The dosage of botolinum injection in the pterygoid muscles will vary between indications and the specific toxin product used, but is usually in the range of 20 – 30 U/ml. Injection dose is 10 U to 50 U per muscle every three months,20 with a total limit of 200 U for muscles of mastication. In the author’s experience, the 20 units of Botox® wear off at two months after injection in a patient with oromandibular dystonia. Pterygoid Botox® injection can be an important ancillary to rehabilitation disorders of mastication and the TMJ. However, it is not without risk. Various complications have been reported such as changes in salivary consistency, swallowing and speech and facial muscle weakness.20 These complications may be attributed to the toxin diffusing to untargeted adjacent structures such as the parotid gland, facial muscles and superior constrictors. Proper technique, sufficient knowledge of pterygoid anatomy and EMG guidance are important in preventing complications. Clinical outcomes for both short- and long-term goals still need to be standardized and defined to allow for approach cannot be overemphasized. Pearls: Short-term and long-term goals should be set. Zygomatic arch and condylar head are good landmarks for lateral pterygoid injection via extra-oral approach. Coronoid process and ramus can be palpated intra-orally when doing medial pterygoid muscle injection. The needle is guided medial to the bone, piercing the retromolar trigone. EMG guidance when using cannula electrodes to inject Botox will facilitate muscle identification. Proper dosing and frequency of Botox injection is individualized
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38

Svensson, P., Antoon De Laat, Thomas Graven-Nielsen, and Lars Arendt-Nielsen. "Experimental jaw-muscle pain does not change heteronymous H-reflexes in the human temporalis muscle." Experimental Brain Research 121, no. 3 (August 10, 1998): 311–18. http://dx.doi.org/10.1007/s002210050464.

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39

Rodrigues, Delaine, Anamaria Oliveira Siriani, and Fausto Bérzin. "Effect of conventional TENS on pain and electromyographic activity of masticatory muscles in TMD patients." Brazilian Oral Research 18, no. 4 (December 2004): 290–95. http://dx.doi.org/10.1590/s1806-83242004000400003.

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Temporomandibular disorders (TMD) are characterized by several signs and symptoms, such as pain and changes in the electrical activity of masticatory muscles. Considering that transcutaneous electrical nerve stimulation (TENS) is a resource indicated to promote analgesia, the objective of this study was to evaluate the effect of TENS on pain and electromyographic (EMG) activity of the jaw elevator muscles in TMD patients. This study evaluated 35 female volunteers: 19 TMD patients (mean age = 23.04 ± 3.5) and 16 normal subjects (mean age = 23.3 ± 3.0). Transcutaneous electrical nerve stimulation (conventional mode, 150 Hz) was applied once to each group for 45 minutes. Surface electromyography (gain of 100 times and 1 kHz sampling frequency) and the visual analogue scale (VAS) were applied before and immediately after TENS application. Both VAS data and root mean square (RMS) values were analyzed using Student's t-test. The TMD group, compared to the control group, showed higher EMG activity of the jaw elevator muscles at rest. No difference was observed between the groups regarding maximum voluntary clenching (MVC). In TMD patients, TENS reduced both pain and EMG activity of the anterior portion of the temporal muscle, increasing the activity of the masseter muscles during MVC. It is possible to conclude that a single TENS application is effective in pain reduction. However, it does not act homogeneously on the features of the electric activity of the muscles evaluated.
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40

Meijs, Suzan, Shaojun Liao, Lars Arendt-Nielsen, Kelun Wang, and Brian E. Cairns. "The pro-algesic effect of γ-aminobutyric acid (GABA) injection into the masseter muscle of healthy men and women." Scandinavian Journal of Pain 20, no. 1 (December 18, 2019): 139–50. http://dx.doi.org/10.1515/sjpain-2019-0056.

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AbstractBackground and aimsPreclinical studies have reported that activation of peripheral γ-aminobutyric acid A (GABAA) receptors may result in analgesia. The current study was conducted in young healthy men (n = 30) and women (n = 28) to determine whether injections of GABA into the masseter muscle reduce pain in a sex-related manner.MethodsThe effect of injection of GABA alone, or in combination with the non-inflammatory algogen glutamate, was assessed in two separate studies. Lorazepam, a positive allosteric modulator of the GABAA-receptor, was co-injected with GABA in both studies to explore the role of this receptor in muscle pain responses of healthy human volunteers. Masticatory muscle mechanical pain intensity was recorded on an electronic visual analogue scale (VAS) while muscle pain sensitivity was assessed by determining the pressure pain threshold (PPT), tolerance and maximal jaw opening (MJO) of the subjects prior to, and again after the various intramuscular injections.ResultsIntramuscular injection of GABA alone was reported to be significantly more painful, in a concentration related manner, than saline control injections, and this pain was further increased by co-injection of lorazepam with GABA. Co-injection of GABA with glutamate was found to significantly increase glutamate-evoked masseter muscle pain in men, but not in women. There was no effect of injections of either GABA alone, or GABA with glutamate, on PPT, tolerance or maximum jaw opening.ConclusionsInjection of GABA into the human masseter muscle appears to excite nociceptors to produce muscle pain without a longer term effect on mechanical pain sensitivity in the muscle. The findings suggest that GABA-mediated pain in humans is produced through peripheral GABAA receptor activation. The mechanism underlying the sex-related difference in the effect of GABA on glutamate-evoked muscle pain was speculated to be due to a methodological artifact.ImplicationsThis study was designed to detect analgesic rather than algesic effects of peripherally administered GABA, and as a result, the concentration of glutamate chosen for injection was close to the maximal pain response for healthy women, based on previously determined pain-concentration response relationships for glutamate. This may explain the finding of greater pain in men than women, when GABA and glutamate were co-injected. Overall, the findings suggest that activation of peripheral GABAA receptors in human masticatory muscle produces pain, possibly due to depolarization of the masticatory muscle afferent fibers.
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Gonzalez, Yoly, Jeffrey Nickel, JoAnna Scott, Hongzeng Liu, and Laura Iwasaki. "Psychosocial Scores and Jaw Muscle Activity in Women." Journal of Oral & Facial Pain and Headache 32, no. 4 (October 2018): 381–88. http://dx.doi.org/10.11607/ofph.2133.

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42

ERNBERG, M., J. H. SCHOPKA, N. FOUGERONT, and P. SVENSSON. "Changes in jaw muscle EMG activity and pain after third molar surgery." Journal of Oral Rehabilitation 34, no. 1 (January 2007): 15–26. http://dx.doi.org/10.1111/j.1365-2842.2006.01695.x.

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43

Horjales-Araujo, E., N. B. Finnerup, T. S. Jensen, and P. Svensson. "Differential effect of visual and gustatory stimuli on experimental jaw muscle pain." European Journal of Pain 17, no. 6 (November 30, 2012): 811–19. http://dx.doi.org/10.1002/j.1532-2149.2012.00253.x.

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44

Shimada, A., L. Baad-Hansen, and P. Svensson. "Effect of experimental jaw muscle pain on dynamic bite force during mastication." Archives of Oral Biology 60, no. 2 (February 2015): 256–66. http://dx.doi.org/10.1016/j.archoralbio.2014.11.001.

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45

Almășan, Oana, Mihaela Hedeșiu, Mihaela Băciuț, Smaranda Buduru, and Cristian Dinu. "Physiotherapy and occlusal splint treatment in myalgia, cervi-cogenic headache, and arthralgia: a case report." Balneo and PRM Research Journal 13, Vol.13, no.3 (September 5, 2022): 518. http://dx.doi.org/10.12680/balneo.2022.518.

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Abstract: The purpose of this study was to describe a rare case of myalgia, cervicogenic headache, and arthralgia in which interaction of physiotherapy, relaxation techniques, cognitive and behavioral counseling, psychosocial support, and occlusal splint treatment resulted in a positive outcome. A 27-year-old woman presented to our clinic with myalgia of the right side of the face, right temporomandibular joint arthralgia, right and left temple pain, jaw elevator muscle pain, and head and neck muscle soreness. The right and left joints' magnetic resonance imaging revealed anterior disc displacement without reduction. The treatment strategy aimed for a non-invasive treatment approach to relieve pain and restore functions. An occlusal appliance with an anterior bite plane was selected, along with counseling, psychosocial support, physiotherapy, posture self-control, massage of the head and neck muscles, mouth opening exercises, and self-massage. A temporomandibular specialist oversaw the splint treatment's progress, a maxillofacial surgeon managed the clinical signs and symptoms of the muscles and joints, and a physiotherapist provided the physiotherapy. Muscle stability in the head and neck has been related to temporomandibular disorders and may have repercussions on craniofacial structure and function. Keywords: physiotherapy; massage; relaxation techniques; oral splint; temporomandibular dis-order
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46

Bendtsen, Lars, Rigmor Jensen, Jannick Brennum, Lars Arendt-Nielsen, and Jes Olesen. "Exteroceptive Suppression Periods in Jaw-Closing Muscles. Variability and Relation to Experimental Pain and Sustained Muscle Contraction." Cephalalgia 13, no. 3 (June 1993): 184–91. http://dx.doi.org/10.1046/j.1468-2982.1993.1303184.x.

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The duration of the late exteroceptive suppression period (ES2) of temporal muscle EMG activity has been reported to be reduced in patients suffering from chronic tension-type headache. Methods of recording and analysing ES2 have varied between centers and reproducibility of results within subjects, although insufficiently studied, has generally been poor. ES2 was investigated in 30 healthy subjects, using a computerized technique of recording, rectifying and averaging the EMG signals. Hour to hour and week to week variations of ES2 durations were calculated, and the influence of pain during a cold pressor test and of sustained muscle contraction on ES2 durations was investigated. The intra-individual variation of ES2 durations was 16.0% from hour to hour and 20.7% from week to week. The inter-individual variation was 36.7%. The present method for analysis of ES2 periods proved to be reliable, as the intra-observer variation was 4.2% and the inter-observer variation 4.6%. ES2 periods were significantly shorter on the first compared to the second day of examination ( p = 0.006) and during experimental pain ( p = 0.0005). We recommend the use of the computerized averaging technique in future studies and caution against the dependence of results upon factors such as conditioning and pain.
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Câmara-Souza, Mariana Barbosa, Alessandro Bracci, Anna Colonna, Marco Ferrari, Renata Cunha Matheus Rodrigues Garcia, and Daniele Manfredini. "Ecological Momentary Assessment of Awake Bruxism Frequency in Patients with Different Temporomandibular Disorders." Journal of Clinical Medicine 12, no. 2 (January 7, 2023): 501. http://dx.doi.org/10.3390/jcm12020501.

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Self-reported awake bruxism (AB) has been associated with temporomandibular disorders (TMD). However, the daily amount of AB behavior has not been quantified in pain patients. Therefore, this study aimed to assess AB frequency in patients with myofascial pain and temporomandibular joint (TMJ) pain and compare it to a group of pain-free individuals. Eighty-four individuals belonging to either a TMD group (n = 54) or a healthy control group (n = 30) were selected. AB frequency was obtained by ecological momentary assessment with a dedicated smartphone application that sent sound alerts at random intervals during the day for one week. Upon receiving the alert, the volunteer reported the current muscular condition and/or the teeth position, i.e., relaxed jaw muscle, jaw bracing, teeth contact, teeth clenching, or teeth grinding. Data were evaluated by independent t-test (α = 0.05). During the seven days, AB frequency was 62.1% ± 26.8% for TMD patients and 36.2% ± 27.3% for pain-free subjects (p < 0.001). Mandible bracing was most common in the TMD group (p < 0.001), while teeth contact, clenching, and grinding did not differ between groups. Moreover, no differences were found in AB frequency between myofascial pain and TMJ pain patients. Therefore, TMD patients have higher AB frequency characterized by jaw bracing, irrespective of pain location.
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Patel, Amit A., Michael Z. Lerner, and Andrew Blitzer. "IncobotulinumtoxinA Injection for Temporomandibular Joint Disorder." Annals of Otology, Rhinology & Laryngology 126, no. 4 (February 1, 2017): 328–33. http://dx.doi.org/10.1177/0003489417693013.

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Objectives: Temporomandibular disorder (TMD) involves dysfunction of the temporomandibular joint and associated muscles of mastication causing pain with chewing, limitation of jaw movement, and pain. While the exact pathophysiology of TMD is not completely understood, it is thought that hyperfunction of the muscles of mastication places stress on the temporomandibular joint, leading to degeneration of the joint and associated symptoms. We hypothesize that chemodenervation of the muscles of mastication with IncobotulinumtoxinA (Xeomin) will decrease the stress on the temporomandibular joint and improve pain associated with temporomandibular joint and muscle disorder (TMJD). Methods: Twenty patients were randomized to IncobotulinumtoxinA (170 units) or saline injection of the masticatory muscles. Patient-reported pain scale (0-10) was recorded at 4-week intervals following injection for 16 weeks. Patients who received saline injection initially were assessed for reduction in pain at the first 4-week interval and if still had significant pain were rolled over into the IncobotulinumtoxinA arm. Results: Preinjection pain scores were similar between patients. While there was a statistically significant reduction in pain score in the placebo group one month, there was an overall larger drop in average pain scores in those patients injected with IncobotulinumtoxinA initially. All patients initially injected with placebo crossed over into the IncobotulinumtoxinA group. Similar results were seen when examining the composite masticatory muscle tenderness scores. There was no significant change in usage of pain medication. Conclusions: We demonstrate utility of IncobotulinumtoxinA in treating patients with TMD with pain despite pain medication usage and other conventional treatments.
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Torisu, Tetsurou, Kelun Wang, Peter Svensson, Antoon De Laat, Hiroyuki Fujii, and Lars Arendt-Nielsen. "Effect of low-level clenching and subsequent muscle pain on exteroceptive suppression and resting muscle activity in human jaw muscles." Clinical Neurophysiology 118, no. 5 (May 2007): 999–1009. http://dx.doi.org/10.1016/j.clinph.2006.11.311.

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50

Koc, Duygu, Arife Dogan, and Bulent Bek. "Bite Force and Influential Factors on Bite Force Measurements: A Literature Review." European Journal of Dentistry 04, no. 02 (April 2010): 223–32. http://dx.doi.org/10.1055/s-0039-1697833.

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Maximum voluntary bite force is an indicator of the functional state of the masticatory system and the level of maximum bite force results from the combined action of the jaw elevator muscles modified by jaw biomechanics and reflex mechanisms. The measurement of bite force can provide useful data for the evaluation of jaw muscle function and activity. It is also an adjunctive value in assessing the performance of dentures. Technological advances in signal detection and processing have improved the quality of the information extracted from bite force measurements. However, these measurements are difficult and the reliability of the result depends on a number of factors, such as presence of pain and temporomandibular disorders, gender, age, cranio-facial morphology, and occlusal factors. In addition to these physiological factors, recording devices and techniques are important factors in bite force measurement. Therefore, one should be careful when comparing the bite force values reported in the research. (Eur J Dent 2010;4:223-232)
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