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1

Pereira Filho, José Lima, Pedro da Silva Gerônimo Neto, João Marcelo Saraiva Ferreira, Pablo de Matos Monteiro, Aglaete de Araújo Pinheiro, Bianca Noelle Batista Nascimento, Mauricio Costa Pinheiro Borralho, Mariele Borges Ferreira, and Crisálida Machado Vilanova. "Estudo morfoanatômico e prospecção fitoquímica de Jatropha multifida L." Research, Society and Development 9, no. 9 (August 20, 2020): e318997309. http://dx.doi.org/10.33448/rsd-v9i9.7309.

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Objetivo: Realizar um estudo morfoanatômico e fitoquímico das folhas de Jatropha multifida, por meio da análise das características macro e microscópicas, assim como a realização de testes para detecção de classes de metabólitos. Metodologia: A análise morfoanatômica da planta foi realizada por meio de secções das faces adaxial e abaxial do limbo foliar e secções transversais do terço médio incluindo a nervura central das folhas da planta, a mão livre, e, posteriormente, coradas com azul de metileno e fucsina e observadas em microscópio óptico. No estudo fitoquímico utilizou-se extrato hidroalcóolico das folhas de Jatropha multifida nos testes para detecção de fenóis, taninos, flavonoides, cumarinas, esteroides, triterpenos, saponinas, alcaloides e resinas. Resultados: A folha de Jatropha multifida apresentou-se verde concolor, acuminada, palmatipartida, hipoestomática com estômatos anomocíticos, epiderme de células com parede curva, mesofilo dorsiventral, feixe vascular colateral e drusas. Em relação aos testes fitoquímicos, foram detectadas as presenças de taninos, cumarinas, esteroides e triterpenos, saponinas e alcaloides. Conclusão: Mediante as observações e testes realizados foi possível caracterizar Jatropha multifida, o que pode auxiliar na diferenciação dessa espécie de outras semelhantes, assim como na padronização dessa matéria-prima vegetal.
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2

Farid, Nurfiddin. "Formulasi Sediaan Gel Basis HPMC Ekstrak Etanol Daun Jarak Cina (Jatropha multifida) Sebagai Penembuhan Luka Sayat pada Tikus Putih (Rattus norvegicus)." Sasambo Journal of Pharmacy 1, no. 2 (September 30, 2020): 57–62. http://dx.doi.org/10.29303/sjp.v1i2.25.

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Saat ini banyak penelitian yang mengembangkan tanaman berkhasiat untuk pengobatan tradisional. Salah satu tanaman yang dapat digunakan sebagai obat tradisional adalah tanaman Jarak cina (Jatropha multifida L). Berdasarkan pengalaman empiris secara turun temurun banyak digunakan oleh masyarakat khususnya Jeneponto, Desa Bulusibatang untuk menyembuhkan luka baru. Di Desa Bulusibatang lebih dikenal dengan tanaman ampicillin (Daun Jarak cina). Pemanfaatan tanaman obat masih perlu terus digali dan dikembangkan berdasarkan penelitian dan pengkajian secara mendalam seiring dengan kemajuan teknologi. Oleh karena itu, peneliti ingin melanjutkan penelitian dengan membuat sediaan farmasi untuk mempermudah penggunaannya secara topikal yaitu sediaan Gel ekstrak etanol Daun Jarak cina (Jatropha multifida L) untuk mengobati luka sayat pada tikus putih (Rattus novergecus). Penelitian ini merupakan penelitian Eksperimental Laboratorium yaitu Uji Efektivitas sediaan Gel ekstrak daun Jarak cina (Jatropha multifida L) terhadap penyembuhan luka sayat pada Tikus putih (Rattus norvegicus). Data hasil pengamatan dianalisis dengan menggunakan metode analisis statistic yaitu analysis of variance (ANOVA) untuk mengetahui rata-rata kelompok perlakuan dan kelompok kontrol. Berdasarkan hasil penelitian, kontrol positif Bioplacenton lebih efektif dibandingkan kontrol negatif. Dan konsentrasi sediaan gel Ekstrak daun Jarak cina (Jatropha multifida) pada konsetrasi 15% yg paling efektif dalam penyembuhan luka sayat dibandingkan dengan konsetrasi 5% dan 10%.
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3

Herwin, Herwin, Rachmat Kosman, and Sri Wahyuni. "ISOLATION AND ACTIVITY ANTIBACTERIAL OF ISOLATES ENDOPHYTE FUNGI OF JATROPH MULTIFIDA L. STEM." Journal Microbiology Science 1, no. 1 (May 19, 2022): 1–8. http://dx.doi.org/10.56711/jms.v1i1.815.

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Endophytic fungi that live on plant tissue has the potential to produce secondary metabolites, same as its host. This study aims to isolation endophyte fungi and antibacterial activity of isolate endophyte fungi of Jatropha multifida L. stem to Escheriacia coli and Staphylococcus aureus bacteria. The preliminary research was performed by isolation endophyte fungi of Jatropha multifida L. stem use PDAC medium and the result of isolation endophyte fungi Jatropha multifida L. stem obtained 6 isolates. Isolates endophyte fungi done examination morphology by microskopic method obtained that islolates have different carasteristic. Based on examination of antibacterial activity by agar diffusion method showed that isolates endophyte fungi that potential as antibacterial is isolate IFJT1 code where isolate IFJT1 code active to Escheriacia coli bacteria obtained inhibitory zone diameter of 17,7 mm and to Staphylococcus aureus bacteria.obtained inhibitory zone diameter of 16,7 mm
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4

KOLAWOLE, Opeyemi Saheed, Abdullahi Alanamu ABDULRAHAMAN, Mahboob Adekilekun JIMOH, and Felix Ayotunde OLADELE. "Morphometric Study of Several Species of the Genus Jatropha Linn. (Euphorbiaceae)." Notulae Scientia Biologicae 8, no. 2 (June 16, 2016): 211–15. http://dx.doi.org/10.15835/nsb829768.

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Morphological parameters of several Jatropha species, namely Jatropha curcas L., Jatropha gossypifolia L., Jatropha podagrica Hook., Jatropha integerrima Jacq. and Jatropha multifida L. were subjected to quantitative analysis within the present study. Twelve traits of the leaves, fruits and seeds were analysed: leaf length, leaf width, leaf length/width ratio, petiole length, petiole width, fruit length, fruit width, fruit length/width ratio, seed length, seed width, fruit stalk length and fruit stalk width were subjected to Principal Component Analysis (PCA) and cluster analysis. Highly significant positive correlations have been noted, while negative correlation was observed between leaf width and leaf length/width ratio, fruit width and leaf length/width ratio. Traits such as leaf length, leaf width and leaf length/width ratio contributed significantly along with other traits to discriminate the studied Jatropha species. J. podagrica and J. integerrima were found to have more similarities, with a stronger coefficient of agglomeration (69.072) than J. curcas and J. podagrica with 315.028 coefficient of agglomeration respectively. The generated dendrogram showed the relationship between the studied Jatropha species, whereas great affinity was noted between J. podagrica and J. multifida as compared with J. gossypifolia and J. integerrima which are distantly related. The closeness observed between J. podagrica and J. multifida is in line with their current sub-generic grouping.
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SAPTADI, DARMAWAN, R. R. SRI HARTATI, ASEP SETIAWAN, BAMBANG HELIYANTO, and SUDARSONO SUDARSONO. "PENGEMBANGAN MARKA SIMPLE SEQUENCE REPEAT UNTUK Jatropha spp." Jurnal Penelitian Tanaman Industri 17, no. 4 (June 19, 2020): 140. http://dx.doi.org/10.21082/jlittri.v17n4.2011.140-149.

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<p>ABSTRAK</p><p>Pemuliaan tanaman jarak pagar (Jatropha curcas L.) untukmenghasilkan varietas berdaya hasil dan berkadar minyak tinggi perludilakukan. Penggunaan marka molekuler dapat membantu mempercepattercapainya tujuan pemuliaan tanaman jarak pagar. Marka simple sequencerepeat (SSR) merupakan marka ko-dominan yang efektif untuk mendu-kung program pemuliaan tanaman, tetapi penerapannya pada jarak pagarmasih terbatas. Penelitian yang dilakukan bertujuan untuk : (i) merancangprimer spesifik SSR menggunakan aksesi DNA jarak pagar yang tersediadi GenBank DNA database dan (ii) mengevaluasi efektivitas pasanganprimer yang dirancang untuk menghasilkan marka SSR yang polimorfikuntuk jarak pagar dan J. multifida. Dua puluh delapan pasang primerspesifik SSR telah berhasil dirancang menggunakan aksesi DNA asal jarakpagar yang ada di GenBank DNA database. DNA genomik jarak pagar danJ. multifida yang diisolasi dapat digunakan sebagai templat untukamplifikasi PCR. Dari 28 pasang primer yang dikembangkan, semuanyamampu menghasilkan marka SSR dari genom jarak pagar dan hanya 19pasang primer yang menghasilkan marka SSR dari genom J. multifida.Dari 19 pasangan primer spesifik SSR yang dievaluasi mampu dihasilkan44 alel dengan ukuran produk amplifikasi berkisar antara 100-360 bp.Sebanyak 35 alel (79,5%) yang diamati merupakan alel yang polimorfik.Marka SSR yang didapatkan tidak polimorfik intra-aksesi jarak pagar atauintra-aksesi J. multifida tetapi polimorfik untuk inter-aksesi kedua spesies.Karena marka SSR yang dihasilkan bersifat polimorfik untuk aksesi jarakpagar dengan aksesi J. multifida maka dapat digunakan sebagai markauntuk mendeteksi hasil persilangan F 1 inter-spesies J. curcas x J. multifida.</p><p>Kata kunci : Jatropha curcas L., jarak pagar, J. multifida, DNA berulang,rancangan primer</p><p>ABSTRACT</p><p>Development of Simple Sequence Repeat Markers forJatropha spp.</p><p>Breeding of physic nut (Jatropha curcas L.) to obtain new varietiesthat are high in yield and oil content needs to be conducted. Molecularmarker could be used to assist breeding of physic nut (J. curcas). Simplesequence repeat (SSR) marker is a co-dominant marker and theoretically itcould be used to support physic nut breeding program. However, onlylimited information has been available regarding molecular analysis ofphysic nut. The objectives of this research were: (i) to design SSR specificprimer based on DNA sequences available in the GenBank DNA databaseand (ii) to evaluate effectiveness of the primer pairs to produce polymor-phic SSR markers for J. curcas and J. multifida. Twenty eight primer pairswere designed and developed using physic nut DNA available in theGenBank DNA database. Total genomic DNA isolated from J. curcas andJ. multifida could be used as DNA templates for PCR amplification. Of the28 primer pairs developed in this research yielded SSR marker using J.curcas genomic DNA, while only 19 out of 28 pairs yielded SSR markersusing J. multifida genomic DNA. As many as 44 alleles with the size ofamplified products ranged from 100-360 bp were identified. Thirty fivealleles (79.5%) out of 44 identified ones were polymorphic. Results ofanalysis indicated that identified SSR markers generated using thedesigned primers were not polymorphic intra accession of J. curcas norintra-accession of J. multifida either. However, the generated SSR markerswere polymorphic for inter-accession of the two Jatropha species. Sincethe generated markers were only polymorphic for J. curcas and J.multifida, they could be used as markers for identifying interspecific F 1hybrids derived from crossing between J. curcas and J. multifida.</p><p>Key words: Jatropha curcas L., physic nut, J. multifida, DNA repeatsequence, primer design</p>
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Lemos, Ari Sérgio de Oliveira, Naiara Norberto Tavares De Oliveira, Lívia Lacerda Netto, Samara Evangelista Reis, Valquíria Pereira De Medeiros, Rodrigo Luiz Fabri, and Luciana Moreira Chedier. "Avaliação do perfil químico e citotóxico de Jatropha multifida L. (Euphorbiaceae) / Chemical and citotoxic perfil evaluation of Jatropha multifida L. (Euphorbiaceae)." Brazilian Journal of Development 7, no. 10 (October 5, 2021): 94971–84. http://dx.doi.org/10.34117/bjdv7n10-010.

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Vieira, Daniglayse Santos, Irinaldo Diniz Basílio Junior, Rossana Teotonio de Farias Moreira, Rodrigo José Nunes Calumby, Rafael Aleixo dos Santos Silva, Valdemir da Costa Silva, and Maria Lysete de Assis Bastos. "Atividade antimicrobiana in vitro do látex da Jatropha multifida L." Research, Society and Development 10, no. 10 (August 12, 2021): e334101017511. http://dx.doi.org/10.33448/rsd-v10i10.17511.

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Jatropha multifida L., conhecida popularmente como mertiolate, é um arbusto, cujas flores vermelhas com anteras amareladas, parecem pequenas peças de coral e caule com presença de látex. É usada na medicina popular para tratar diversas afecções, como feridas infectadas, úlceras e dermatoses. O objetivo do estudo foi verificar a atividade antimicrobiana do látex in natura e liofilizado da J. multifida. Trata-se de pesquisa quantitativa, do tipo experimental. O látex foi coletado no município de Igreja Nova – Alagoas, utilizando-se o método de sangria, em que se realizou cortes oblíquos no caule, obtendo-se o extrato in natura. Já para obtenção do extrato em pó, utilizou-se a liofilização do material in natura. Para avaliação da atividade antimicrobiana foi empregado o método de microdiluição em caldo para determinação da Concentração Inibitória Mínima (CIM), seguido de plaqueamento em ágar para obtenção da Concentração Bactericida Mínima (CBM) dos extratos frente aos microrganismos padronizados pela American Type Culture Collection – ATCC: S. aureus (25923) S. epidermidis (31488), E. faecalis (29212), P. aeruginosa (27853), E. coli (25922), E. aerogenes (13048) e Concentração Fungicida Mínima (CFM) para C. albicans (24433). Os resultados apontaram que ambos os extratos do látex da J. multifida apresentaram uma atividade antimicrobiana moderada contra a maioria das cepas bacterianas testadas e uma atividade fúngica fraca frente a C. albicans, com destaque para o extrato liofilizado. Conclui-se que os extratos foram mais promissores contra as cepas de S. aureus, S. epidermidis, E. faecalis e P. aeruginosa, abrindo possibilidades para evolução de estudos complementares.
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8

N. Tavares de Oliveira, Naiara, Ari Sérgio Oliveira Lemos, Ana Patrícia de Oliveira Pereira, Rodrigo Luiz Fabri, and Luciana Moreira Chedier. "Antifungal Activity of Latex and Lupenonefrom Jatropha multifida L. (Euphorbiaceae)." Revista Virtual de Química 11, no. 5 (2019): 1579–90. http://dx.doi.org/10.21577/1984-6835.20190110.

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9

Syam, Akhirul Kahfi, Muhamad Insanu, and Komar Ruslan Wirasutisna. "ISOLATION OF 8-HIDROXY-6,7-DIMETHOXY COUMARIN FROM JARAK TINTIR STEM (Jatropha multifida L.) AND ITS TOXICITY VALUE USING BRINE SHRIMP LETHALITY TEST (BSLT)." Majalah Obat Tradisional 22, no. 1 (April 26, 2017): 21. http://dx.doi.org/10.22146/tradmedj.24303.

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Jatropha multifida L. (jarak tintir) was a shrub, annual, and had ± 2 m high. Empirically jarak tintir sap was used as traditional medicine by Indonesian people for a long time. Only limited studies were conducted regarding its chemical compound. It was reported that multifidone (diterpenoid compound from the stem) had an activity against cancer cells in vitro. This study aimed to test the toxicity of various extracts (n-hexane, ethyl acetate, and methanol) with Brine Shrimp Lethality Test (BSLT) of Jatropha multifida L. stem. A Fraxidin (8-hidroxy-6,7-dimethoxy coumarin) has been isolated from ethyl acetate fraction based on highest cytotoxic with LC50 value 3.69 µg/mL. The isolated compound was elucidated to gain chemical structure base on spectroscopic data (UV-Vis Spectrofotometric, IR Spectrofotometric, and NMR). Toxicity of fraxidin was tested on BSLT and showed no potential activity with LC50 value > 500 μg/mL.
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Syam, Akhirul Kahfi, Julia Ratnawati, Desti Hermawati, and Puspita Satriyani Permatasari Surasa. "Uji antioksidan dan bioaktivitas fraksi etil asetat batang jarak tintir (Jatropha multifia L.)." Riset Informasi Kesehatan 9, no. 1 (June 29, 2020): 64. http://dx.doi.org/10.30644/rik.v9i1.329.

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Abstrak Latar Belakang: Jatropha multifida L. atau jarak tintir merupakan tanaman yang digunakan secara empiris getahnya sebagai obat luka oleh masyarakat Indonesia sejak lama. Penelitian ini merupakan lanjutan dari penelitian sebelumnya mengenai batang jarak tintir yang telah diuji toksisitas dengan metode BSLT dan peredaman antioksidan dengan metode DPPH yang secara berturut memberikan nilai LC50 terendah 3,69 µg/mL dan IC50 56,85 µg/mL pada ekstrak etil asetat. Metode: Penelitian meliputi tahap-tahap pengumpulan bahan uji batang jarak tintir, penyiapan simplisia, pembuatan ekstrak dengan 3 pelarut yang berbeda kepolarannya penapisan fitokimia dari simplisia, fraksinasi menggunakan metode Kromatografi Cair Vakum (KCV) dari ekstrak etil asetat menjadi 4 fraksi. Hasil: Hasil pengujian antioksidan metode peredaman DPPH memberikan IC50 terhadap f1 (n-heksan 75%:etil asetat 25%), f2 (n-heksan 50%:etil asetat 50%), f3 (n-heksan 25%:etil asetat 75%), dan f4 (etil asetat 100%) secara berturut-turut adalah 3759,79 µg/mL; 790,94 µg/mL; 167,41 µg/mL; dan 164,82 µg/mL. Hasil pengujian BSLT terhadap fraksi etil asetat memberikan hasil LC50 sebesar f1 64,43 µg/mL; f2 37,54 µg/mL; f3 41,94 µg/mL; dan f4 25,70 µg/mL. Kesimpulan: F4 merupakan fraksi dengan nilai IC50 dan LC50 yang paling rendah dari seluruh fraksi, yang menunjukkan f4 merupakan fraksi yang paling aktif sebagai antioksidan dan BSLT serta diduga golongan flavonoid yang diketahui dari profil kromatogram KLT dengan Rf 0,57 yang memberikan hasil positif terhadap penampak bercak FeCl3 dan AlCl3 merupakan senyawa aktif dari kedua aktifitas tersebut. Kata kunci: Antioksidan, Brine Shrimp Lethality Test, DPPH, Jatropha multifida L. ANTIOXIDANT AND BIOACTIVITY ASSAYS OF ETHYL ACETATE FRACTION OF JARAK TINTIR STEM (Jatropha multifida L) Abstract Background: Jatropha multifida L. or jarak tintir was empirically used as wound treatment for the sap by Indonesian people for a long time ago. The toxicity and antioxidant capacity of the jarak tintir stem was done by brain shrimp lethality test (BSLT) with LC50 3,69 µg/mL and DPPH scavenging activity with IC50 56,85 µg/mL for ethyl acetate extract. Method: Extraction was performed by continuous extraction with Soxhlet apparatus using various polarity solvents (n-hexane, ethyl acetate, and methanol) and ethyl acetate extract was fractioned by vacuum liquid chromatography (VLC) into 4 fraction with gradien eluen of n-hexane and ethyl acetate. Results: Antioxidant assay gave IC50 for f1 (n-hexane 75%:ethyl acetate 25%), f2 (n-hexane 50%: ethyl acetate 50%), f3 (n-hexane 25%: ethyl acetate 75%), and f4 (ethyl acetate 100%) respectively as 3759,79 µg/mL; 790,94 µg/mL; 167,41 µg/mL; and 164,82 µg/mL. BSLT assays for each fractions gave LC50 as f1 64,43 µg/mL; f2 37,54 µg/mL; f3 41,94 µg/mL; and f4 25,70 µg/mL. Conclusion: Fraction 4 was the best fraction with the lowest IC50 and LC50 with flavonoid was suspected as responsible compound for both assays after TLC analysis that gave spot with Rf 0.57 and gave positive result after sprayed with FeCl3 dan AlCl3 spray reagent. Keywords: Antioxidant, Brine Shrimp Lethality Test, DPPH, Jatropha multifida L
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Fitria, Annisa. "The Bactericidal and Antibiofilm Activity of Stem Bark of Jatropha multifida L. Against Staphylococcus aureus and MRSA." JURNAL EKSAKTA 18, no. 1 (March 20, 2018): 42–55. http://dx.doi.org/10.20885/eksakta.vol18.iss1.art5.

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Chronical wound often caused by bacteria which has antibiotic resistance characteristic and presence of biofilm formation. This study aims to evaluate the bactericidal and antibiofilm activity of stem bark of Jatropha multifida L. against Staphylococcus aureus and MRSA (Methicillin-Resistant Staphylococcus aureus), as alternative antimicrobial agents. Examination of bactericidal activity of the extract was performed by time-kill assay to determine the speed of the extract to eradicate bacteria. The inhibitory activity of extract toward biofilm production was quantified using spectrophotometric method. The extract showed bactericidal activity which can be achieved at 8 hours and 12 hours against Staphylococcus aureus and MRSA in MBC value of 0.5 mg/mL and 1 mg/mL. The extract exhibited antibiofilm activity which indicates by its IC50 value of 0.3 mg/mL and 0.76 mg/mL against Staphylococcus aureus and MRSA. These experiments have shown the potential of the extract of  Jatropha multifida L. stem bark as a bioactive substance in a topical agent for chronical skin infection. Â
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Anani, Kokou, Yao Adjrah, Yaovi Ameyapoh, SimpliceDamintoti Karou, Amegnona Agbonon, Comlan de Souza, and Messanvi Gbeassor. "Antimicrobial, Anti-inflammatory and antioxidant activities of Jatropha multifida L. (Euphorbiaceae)." Pharmacognosy Research 8, no. 2 (2016): 142. http://dx.doi.org/10.4103/0974-8490.172657.

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Fitria, Annisa, Dina Nur Upziah, and Satria Lakna Widya Lestari. "STUDI AKTIVITAS DAN ANALISIS KANDUNGAN SENYAWA ANTIOKSIDAN BATANG JATROPHA MULTIFIDA L." Jurnal Ilmiah Farmasi 12, no. 2 (September 18, 2016): 15–26. http://dx.doi.org/10.20885/jif.vol12.iss2.art2.

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Christian Prasgi, Henokh, and Sri Kasmiyati. "Analisis Hubungan Kekerabatan Fenetik Famili Euphorbiaceae di Kota Salatiga berdasarkan Karakter Morfologi serta Sifat Kimia." Jurnal Biologi Indonesia 18, no. 1 (2022): 67–78. http://dx.doi.org/10.47349/jbi/18012022/67.

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Euphorbiaceae is the most diverse angiosperm plant with one of the largest number of species widely used in various industries. Exploration and inventory of the Euphorbiaceae family has not been maximized, including in Salatiga City. Its great potential requires an initial step, namely plant breeding, but knowledge of its phenetic relationships is needed so that plant breeding produces superior individuals. In addition to morphological characters, chemical properties such as milk clotting activity are important in understanding the phenetic relationships. This study aims to analyze the phenetic relationships of Euphorbiaceae members in Salatiga City based on their morphological and chemical characteristics as well as from the milk clotting activity. Twenty five individual members of the Euphorbiaceae were analyzed for their morphological and chemical characteristics, and 30 characters were obtained. The results of the study using Cluster Analysis method showed that 25 individuals formed cluster A which was divided into 2 parts (clusters C and D) and cluster B formed cluster G (consists of individuals of Codiaeum variegatum (L.) Bl.). The closest phenetic relationships between Jatropha multifida Sidomukti C09 and Jatropha multifida Sidorejo C18 with a dissimilarity index of 0.03% or the equation 99.97%. The most distant phenetic relationships in Codiaeum variegatum (L.) Bl. Sidorejo C11 and Codiaeum variegatum (L.) Bl. Sidomukti C03 with a dissimilarity index of 19.13% or the equivalent percentage of 80.87%. The genus Euphorbia formed cluster F. The genus Manihot and Jatropha formed cluster C, the genus Codiaeum formed clusters E and B. All individuals, except Codiaeum variegatum (L.) Bl. Sidorejo C11, can coagulate milk so that it has potential as a protease enzyme in various industries. The highest protease enzyme activity value was in Codiaeum variegatum (L.) Bl. Sidorejo C11 (15.84 U/mg) and the lowest was in Euphorbia tirucalli Sidomukti C07 (2.34 U/mg).
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Christian Prasgi, Henokh, and Sri Kasmiyati. "Analisis Hubungan Kekerabatan Fenetik Famili Euphorbiaceae di Kota Salatiga berdasarkan Karakter Morfologi serta Sifat Kimia." Jurnal Biologi Indonesia 18, no. 1 (2022): 67–78. http://dx.doi.org/10.47349/jbi/18012022/67.

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Euphorbiaceae is the most diverse angiosperm plant with one of the largest number of species widely used in various industries. Exploration and inventory of the Euphorbiaceae family has not been maximized, including in Salatiga City. Its great potential requires an initial step, namely plant breeding, but knowledge of its phenetic relationships is needed so that plant breeding produces superior individuals. In addition to morphological characters, chemical properties such as milk clotting activity are important in understanding the phenetic relationships. This study aims to analyze the phenetic relationships of Euphorbiaceae members in Salatiga City based on their morphological and chemical characteristics as well as from the milk clotting activity. Twenty five individual members of the Euphorbiaceae were analyzed for their morphological and chemical characteristics, and 30 characters were obtained. The results of the study using Cluster Analysis method showed that 25 individuals formed cluster A which was divided into 2 parts (clusters C and D) and cluster B formed cluster G (consists of individuals of Codiaeum variegatum (L.) Bl.). The closest phenetic relationships between Jatropha multifida Sidomukti C09 and Jatropha multifida Sidorejo C18 with a dissimilarity index of 0.03% or the equation 99.97%. The most distant phenetic relationships in Codiaeum variegatum (L.) Bl. Sidorejo C11 and Codiaeum variegatum (L.) Bl. Sidomukti C03 with a dissimilarity index of 19.13% or the equivalent percentage of 80.87%. The genus Euphorbia formed cluster F. The genus Manihot and Jatropha formed cluster C, the genus Codiaeum formed clusters E and B. All individuals, except Codiaeum variegatum (L.) Bl. Sidorejo C11, can coagulate milk so that it has potential as a protease enzyme in various industries. The highest protease enzyme activity value was in Codiaeum variegatum (L.) Bl. Sidorejo C11 (15.84 U/mg) and the lowest was in Euphorbia tirucalli Sidomukti C07 (2.34 U/mg).
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Franyoto, Yuvianti Dwi, Lia Kusmita, Mutmainah, and Riega Demma Angrena. "Total flavonoid content and formulation antioxidant cream stem of jatropha multifida l." Journal of Physics: Conference Series 1025 (May 2018): 012130. http://dx.doi.org/10.1088/1742-6596/1025/1/012130.

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OLADIPO, Olaniran Temitope, and Herbert Chukwuma ILLOH. "Leaf Protein Electrophoresis and Taxonomy of Species of Jatropha L. (Euphorbiaceae)." Notulae Scientia Biologicae 4, no. 3 (August 30, 2012): 92–96. http://dx.doi.org/10.15835/nsb437601.

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The systematic relationship existing among members of the all important genus Jatropha was studied using leaf protein electrophoresis. The aim was to identify possible taxonomic importance of the protein profile in the estimation and elucidation of the taxonomic affinity of the six species of Jatropha (Jatropha curcas Linn., J. podagrica Hook., J. gossypifolia Linn., J. mutifida Linn., J. tanjorensis Ellis & Saroja and J. integerrima Linn.) found in Nigeria. The species were screened for total protein banding patterns using gel electrophoresis. Young leaves (0.8 g) of the plants were washed with distilled water and macerated with sterile mortar and pestle in 0.8% Phosphate Buffer-Saline (PBS) containing 0.4 M NaCl at pH 8.0. Results reveal that protein banding pattern was taxon specific. Generic band occurs at 8.3. The highest number of interspecific bands (4) exists between J. podagrica and J. multifida. Variations exist not only in the number of bands but also in the intensity of the bands. Sokal and Sneath coefficient of similarity ranges between 11.1-44.4 %. Single linkage Cluster Analysis (SLCA) of the relative mobility values of the protein in the taxa shows partial agreement with current sub generic and sectional delimitation of the species based on morphology and anatomy of the species.
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Enderlei Dec and Denise Monique Dubet da Silva Mouga. "Contribuição à morfologia polínica de plantas medicinais apícolas (Euphorbiaceae Juss. & Lamiaceae Martinov)." Acta Biológica Catarinense 1, no. 1 (June 23, 2014): 44–52. http://dx.doi.org/10.21726/abc.v1i1.601.

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Em função da variabilidade dos tipos polínicos, sua descrição morfológica constitui suporte para diversas finalidades e estudos. Estão descritas neste trabalho 13 espécies polínicas de interesse apícola, sendo seis da família Euphorbiaceae (Euphorbia milii des Moul., E. pulcherrima Willd. ex Klotzsch, Jatropha curcas L., J. gossypiifolia L., J. multifida L. e Ricinus communis L.) e sete de Lamiaceae (Solenostemon scutellarioides (L.) Codd., Mentha x villosa Huds., Ocimum basilicum L., O. gratissimum L., Plectranthus grandis (L. H. Cramer) R. Willemse, P. neochilus Schlechter e Tetradenia riparia (Hochst.) Codd.). Os grãos foram preparados por acetólise, fotografados e caracterizados quanto a tamanho, forma, aberturas e ornamentação externa. A família Euphorbiaceae mostrou-se euripalinológica com grãos isopolares, de simetria radial, próximos da forma esferoidal, 3-colporados ou atremados (gênero Jatropha), com endoaberturas lalongadas em Euphorbia milii, E. pulcherrima e Ricinus communis, além de exina variando entre fina e espessa, bem como ornamentação reticulada, exceto para Ricinus (psilado). Em Lamiaceae, os grãos apresentaram-se isopolares, com simetria radial, formas que variavam de oblato a prolato, 6-colpados, com exina pouco variável, ornamentação sempre reticulada, sem endoaberturas, caracterizando uma família estenopalinológica.
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Silvia, Mega, Aditya Fridayanti, and Laode Rijai. "Kajian Stabilitas Fisika dan Aktivitas Sebagai Obat Luka Getah Jarak Cina (Jatropha multifida L.)." Proceeding of Mulawarman Pharmaceuticals Conferences 3 (April 26, 2016): 290–95. http://dx.doi.org/10.25026/mpc.v3i2.123.

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Jarak cina memiliki getah yang telah terbukti dapat digunakan sebagai obat luka sayat.Masyarakat biasanya hanya memanfaatkan getah jarak cina yang baru diambil, cara tersebut dirasakan kurang efektif, akan lebih baik jika getah dapat disimpan untuk penggunaan darurat sewaktu waktu, namun untuk hal tersebut perlu diperhatikan stabilitas dari getah selama penyimpanan, karena ada kemungkinan terjadinya perubahan stabilitas fisika yang mempengaruhi stabilitas aktivitas dari getah sebagai obat luka sayat.Penelitian ini bertujuan untuk mengetahui pengaruh perubahan stabilitas fisika terhadap aktivitas getah dan mengetahui waktu penyimpanan yang efektif untuk getah jarak cina.Jenis penelitian adalah penelitian laboratorium eksperimental, pengujian yang dilakukan menggunakan adalah mencit sebanyak 21. Mencit dibagi menjadi 7 kelompok yaitu 1 (kontrol positifpovidon iodine), 2 (kontrol negatif tanpa perlakuan), 3 (getahsegar), 4 (getah minggu ke-1), 5 (getah minggu ke-2), 6 (getah minggu ke-3) dan 7 (getah minggu ke-4). Analisis yang digunakan dalam penelitian ini adalah analisis deskriptif.Hasil penelitian yang diperoleh getah pada minggu ke-1 hingga minggu ke-3 memiliki nilai aktivitas yang cukup baik walaupun pada minggu ke-1 sudah terjadi perubahan stabilitas fisika, waktu penyimpanan yang efektif untuk getah adalah 3 minggu.
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Lestari, Dyan Ayu, Wisnu Cahyo Prabowo, and Muhammad Amir Masruhim. "Aktivitas Antifungi Getah Jarak Cina (Jatropha multifida L.) pada Pertumbuhan Malassezia globosa Penyebab Ketombe." Proceeding of Mulawarman Pharmaceuticals Conferences 3 (April 26, 2016): 164–67. http://dx.doi.org/10.25026/mpc.v3i2.103.

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Indonesia memiliki bermacam-macam tanaman obat tradisional untuk mengobati ketombe, diantaranya menggunakan getah jarak cina. Getah Jarak Cina (Jatropha multifida Linn.) diketahui memiliki beberapa metabolit sekunder yang beraktivitas sebagai antifungi. Metabolit sekunder tersebut fenol, saponin, alkaloid dan polisakarida. Penelitian ini bertujuan untuk menguji aktivitas antifungi getah jarak cina variasi konsentrasi 10%-100% dan membandingkan dengan kontrol positif zinc pyrithione 1%. Aktivitas antifungi diuji pada Malassezia globosa dengan menggunakan metode disc diffusion Kirby-Bauer berupa Konsentrasi Hambat Minimum (KHM) dan Konsentrasi Bunuh Minimum (KBM). Hasil uji menunjukkan bahwa getah jarak cina mampu menghambat pertumbuhan Malassezia globosa penyebab ketombe. Data dianalisis dengan analisis varians (ANAVA) satu arah dan dilanjutkan dengan uji LSD (Least Significance Difference). Hasil analisis menunjukkan konsentrasi uji dan kontrol memiliki aktivitas antifungi. Getah jarak cina memiliki potensi aktivitas yang rendah dibandingkan dengan zinc pyrithione 1%. Getah jarak cina diketahui masih berpotensi menjadi sumber zat antifungi baru terhadap pertumbuhan Malassezia globosa penyebab ketombe.
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Ivan, Ivan, Sunarjati Sudigdoadi, and Achmad Hussein S. Kartamihardja. "Antibacterial Effect of Jatropha multifida L. Leaf Infusion towards Staphylococcus aureus and Pseudomonas aeruginosa." Althea Medical Journal 6, no. 2 (June 2019): 95–99. http://dx.doi.org/10.15850/amj.v6n2.1622.

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Affandy, Fidrus, Dyke Gita Wirasisya, and Nisa Isneni Hanifa. "Skrining fitokimia pada tanaman penyembuh luka di Lombok Timur." Sasambo Journal of Pharmacy 2, no. 1 (April 30, 2021): 1–6. http://dx.doi.org/10.29303/sjp.v2i1.84.

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The ethnomedicinal study which conducted in East Lombok revealed 5 potentially plants that have wound healing properties (Jatropha multifida L., Stachytarpheta jamaicensis (L.) Vahl, Centella asiatica (L.) Urban, Euphorbia pulcherrima Willd, and Angelica keiskei). The five plants have been no further research related to the presence of compounds that have activity in wound healing. This study aims to screen the plants secondary metabolites from above plants. The sample was maserated with 96% solvent methanol. The viscous extract was determined by physical characterization including consistency and color as well as chemical characterization, namely the phytochemical screening test. The results showed that the five plants contained flavonoids, phenolics, saponins, and steroids, except for Stachytarpheta jamaicensis (L.) Vahl showed negative results for saponins and Angelica keiskei showed negative results for steroid compounds. Keywords: phytochemical screening, total phenolic content, wound healing herbs, East Lombok
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Kodir, Ade Ismail Abdul, Muhamat Muhtar S. Abdurrohman, and Talitha Novi Rahmaningrum. "THE EFFECT OF PERIODONTAL PACK WITH ADDITIONAL PLANTS OF IODINE (JATROPHA MULTIFIDA L.) POST CURRETAGE." Jurnal Medali 4, no. 2 (September 23, 2022): 104. http://dx.doi.org/10.30659/medali.4.2.104-109.

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Background: Curettage is an act of scraping the granulation tissue on the lateral gingival wall of the periodontal pocket. After curettage, a periodontal pack was applied to control bleeding and keep the wound area clean. The addition of iodine leaves as an alternative because it contains flavonoids that can help the wound healing process. This study aims to determine the effect of adding 10% iodine leaf extract gel on the curettage process.Method: A true experimental laboratory study with a post-test only control group design on 20 wistar rats. The periodontal pack group and the periodontal pack group were added with 10% iodine leaf extract gel. Curettage healing was seen from the mean number of fibroblasts using One-Way Anova analysis.Result: The study showed the mean number of fibroblasts on the 5th and 7th day periodontal pack groups were 35.20 and 49.60, while those in the periodontal pack group with the addition of iodine leaf extract gel on 5th and 7th days were 45.80 and 50.80, respectively. The One-Way Anova test showed p > 0.05, there was a significant difference in the mean number of fibroblasts between the study groups.Conclusion: The conclusion is that there is an effect of giving 10% iodine leaf extract gel on the number of fibroblasts in the healing process of wistar rat curettage.
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Chokchaisiri, Ratchanaporn, Jaranwit Srijun, Waraluck Chaichompoo, Sarot Cheenpracha, Lucksagoon Ganranoo, and Apichart Suksamrarn. "Anti-herpes simplex type-1 (HSV-1) activity from the roots of Jatropha multifida L." Medicinal Chemistry Research 29, no. 2 (December 5, 2019): 328–33. http://dx.doi.org/10.1007/s00044-019-02484-5.

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Rusdy, Hendry, and Diah HI Damanik. "Antibacterial activity of Betadine (Jatropha multifida L.) stem extract on Pseudomonas aeruginosa growth in vitro." F1000Research 11 (October 27, 2022): 1222. http://dx.doi.org/10.12688/f1000research.123777.1.

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Background: Today, people use plants to treat various types of diseases and improve human health. One of the medicinal plants is the Betadine plant (Jatropha multifida L.). Betadine plants have many functions, especially the sap, leaves, fruit and seeds. The compound contents in Betadine stem sap, which is efficacious as an antimicrobial, are saponins, tannins, flavonoids and labaditin. One of the bacteria that cause infection is Pseudomonas aeruginosa. These bacteria can cause opportunistic and nosocomial infections. Methods: This study was a true experimental laboratory with a post-test only control group design. This study used Betadine stem sap extract with concentrations of 25%, 50%, 75%, 100%, gentamicin cream 10% as positive control, and dimethyl sulfoxide (DMSO) solution as negative control. This study used the Kirby-Bauer diffusion method and the bacterium Pseudomonas aeruginosa was grown on nutrient agar media, then incubated for 24 hours and calculated using calipers. Research data were analyzed using one-way ANOVA test. Results: The highest inhibition zone was group 50% (12.725 ± 0.2500 mm) while the lowest inhibition zone was group 100% (8.675 ± 0.5620 mm). Conclusions: Betadine stem extract had antibacterial activity in inhibiting the growth of Pseudomonas aeruginosa bacteria, with the 50% concentration being the most effective in inhibiting the growth of Pseudomonas aeruginosa bacteria.
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Rusdy, Hendry, Astri Suryani Pasaribu Saruksuk, Rahmi Syaflida Dalimunte, and Gostry Aldica Dohude. "Efektivitas getah batang betadine (Jatropha multifida L.) terhadap penyembuhan luka pasca pencabutan gigi pada tikus Sprague-DawleyEffectiveness of betadine (Jatropha multifida L.) stem sap on the wound healing after tooth extraction in Sprague-Dawley rats." Jurnal Kedokteran Gigi Universitas Padjadjaran 33, no. 2 (August 31, 2021): 145. http://dx.doi.org/10.24198/jkg.v33i2.32563.

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Pendahuluan: Pencabutan gigi merupakan prosedur yang sering dilakukan di kedokteran gigi. Setelah pencabutan gigi akan dihasilkan suatu perlukaan. Proses penyembuhan luka dapat dipercepat pada kondisi tertentu. Salah satu bahan alami yang dapat membantu proses penyembuhan luka adalah getah tanaman betadine (Jatropha multifida L.). Penelitian bertujuan untuk menganalisis efektivitas getah tanaman betadine terhadap penyembuhan luka dan terhadap tanda-tanda infeksi pasca pencabutan gigi Metode: Desain penelitian studi eksperimental laboratorium dengan rancangan penelitian post-test only control group design menggunakan 30 ekor tikus Sprague-Dawley. Teknik pengambilan sampel yaitu convenience sampling. Sampel dibagi menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Kelompok perlakuan diberikan getah tanaman betadine dan kelompok kontrol diberikan asam traneksamat secara oral menggunakan sonde lambung. Tunggu selama 4 jam setelah pemberian getah tanaman betadine dan asam traneksamat. Anestesi pada tikus menggunakan ketamin 50 mg/kg berat badan secara intramuskular kemudian dilakukan pencabutan pada gigi tikus. Pengamatan dilakukan dengan melihat kriteria klinis pada hari 1,3,7 dan diperhatikan sampai luka sembuh serta lihat tanda-tanda infeksi. Analisis data dilakukan dengan uji normalitasShapiro Wilik. Hasil penelitian menunjukkan bahwa data berdistribusi tidak normal. Analisis data dilanjutkan menggunakan uji statistik mann whitney. Hasil: Terdapat perbedaan signifikan penyembuhan luka soket pasca pencabutan gigi setelah diberikan getah betadine dan asam traneksamat dengan nilai p=0,037 (p<0,005). Simpulan: Pemberian getah tanaman betadine terbukti lebih efektif terhadap proses penyembuhan luka soket pasca pencabutan gigi dibandingkan dengan pemberian asam traneksamat. Kata kunci: tikus Sprague-Dawley; penyembuhan luka; pencabutan gigi; getah batang betadine ABSTRACTIntroduction: Tooth extraction is a procedure often performed in dentistry. Tooth extraction will always cause injuries. However, the wound healing process can be accelerated under certain conditions. One of the natural ingredients that can accelerate the wound healing process is betadine (Jatropha multifida L.) plant sap. The study was aimed to analyzed the effect of betadine plant sap on wound healing and signs of infection after tooth extraction. Methods: Experimental laboratory study design with post-test only control group design was conducted towards 30 Sprague-Dawley rats. The sampling technique was convenience sampling. The sample was divided into two groups, the treatment group and the control group. The treatment group was administered with betadine plant sap, and the control group was administered with tranexamic acid orally using a gastric probe, then waited 4 hours after. The anaesthesia was then performed using 50 mg/kg body weight of ketamine intramuscularly. The extraction was performed after. Observations was conducted at the clinical criteria on days 1, 3, and 7 and continue to be monitored until the wound heals. Then, the signs of infection were observed. Data analysis was carried out using the Shapiro Wilk normality test. The results showed that the data was not normally distributed. Thus, data analysis was continued using the Mann Whitney statistical test. Results: The results showed a significant difference in the healing of socket wounds after tooth extraction after being administered with betadine sap and tranexamic acid with a value of p=0.037 (p<0.005). Conclusions: Administration of betadine plant sap is proven to be more effective in accelerating the healing process of socket wounds after tooth extraction than tranexamic acid. Keywords: Sprague-Dawley rats; wound healing; pencabutan gigi; getah batang betadine
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Aryantini, Dyah, Erni Anika Sari, and Dani Nanda S.W. "KARAKTER SPESIFIK EKSTRAK DAUN YODIUM (Jatropha multifida L.) DARI TIGA LOKASI TEMPAT TUMBUH DI JAWA TIMUR." Journal of Pharmacy Science and Technology 3, no. 1 (April 18, 2021): 156. http://dx.doi.org/10.30649/pst.v3i1.109.

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Wintola, O. A., E. O. Ajayi, and A. J. Afolayan. "GC-MS Profile of Volatile Oils Extracted from Jatropha multifida L. using Hydrodistillation and Solvent-Free Microwave Extraction Methods." Asian Journal of Chemistry 31, no. 5 (March 28, 2019): 1143–48. http://dx.doi.org/10.14233/ajchem.2019.21338.

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Volatile oils were extracted from the leaves of Jatropha multifida using solvent free microwave and hydrodistillation methods and the oils obtained were analyzed by gas chromatography-mass spectrometry (GC-MS). The major compound as observed is eucalyptol with 70.38 and 35.62 % for solvent-free microwave extraction (SME) and hydrodistillation extraction (HDE), respectively. The oil compositions were dominated by oxygenated compounds. Oxygenated monoterpenes were prevalent in contrast to monoterpenes hydrocarbons. The oils were also characterized by oxygenated sesquiterpenes (SME, 6.05 %; HDE, 7.34 %). This study may provide information on a suitable method of extraction of the essential oil for industrial application and may assist in the realization of the essential oil as a natural source of plant and animal food additives. These various bioactive compounds in the essential oil may partially justify their use in folklore medicine.
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Nugroho, Kristianto, Rerenstradika T. Terryana, Reflinur Reflinur, Puji Lestari, Karden Mulya, and I. Made Tasma. "Keragaman Genetik Dua Puluh Aksesi Plasma Nutfah Jatropha spp. Menggunakan Marka Simple Sequence Repeat." Jurnal AgroBiogen 13, no. 1 (March 7, 2018): 17. http://dx.doi.org/10.21082/jbio.v13n1.2017.p17-24.

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<p>Jarak pagar (<em>Jatropha</em><em> </em><em>curcas</em> L.) merupakan salah satu tanaman yang potensial sebagai penghasil energi alternatif bahan bakar fosil. Informasi mengenai keragaman genetik genus <em>Jatropha</em> spp. sangat penting untuk menentukan arah kegiatan pemuliaan ke depan. Tujuan penelitian ini adalah menganalisis keragaman genetik 20 aksesi plasma nutfah <em>Jatropha</em> spp. asal Indonesia dan Thailand menggunakan 20 marka SSR. Sebanyak 129 alel berhasil dideteksi dengan rentang 4-9 alel per lokus dan rerata 6,5 alel. Nilai diversitas gen sebesar 0,53 hingga 0,86 dengan rerata 0,75, sedangkan nilai PIC sebesar 0,49 hingga 0,84 dengan rerata 0,71. Sebanyak 12 marka memiliki nilai PIC &gt; 0,70 dan bersifat informatif untuk membedakan individu jarak. Rerata frekuensi alel utama yang diperoleh sebesar 37% dengan rentang 18–55%. Sebanyak 7 marka SSR mampu membedakan genotipe heterozigot dengan nilai heterozigositas sebesar 0,05 hingga 0,11 dengan rerata 0,03. Hasil analisis filogenetik menunjukkan bahwa 20 aksesi <em>Jatropha</em> spp. memisah menjadi dua klaster utama pada koefisien kesamaan 0,70. Klaster pertama terdiri atas 17 aksesi <em>J. curcas</em>,<em> </em>sedangkan klaster kedua terdiri atas 3 aksesi, yaitu <em>J. podagrica</em>, <em>J. gossypifolia</em>, dan <em>J. multifida</em>. Data keragaman genetik yang diperoleh pada penelitian ini dapat dimanfaatkan sebagai dasar pemilihan tetua persilangan dalam rangka menghasilkan varietas unggul baru dengan karakter kadar minyak tinggi sesuai yang diharapkan.</p>
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Victorien, Dougnon Tamègnon, Klotoé Jean Robert, Dougnon Tossou Jacques, Sègbo Julien, Atègbo Jean-Marc, Loko Frédéric, and Dramane Karim. "Hemostatic activity screening and skin toxicity of sap of Jatropha multifida L. (Euphorbiaceae) used in traditional medicine (Benin)." Toxicology Letters 221 (August 2013): S231. http://dx.doi.org/10.1016/j.toxlet.2013.05.560.

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Victorien, Dougnon Tamègnon, Klotoé Jean Robert, Dougnon Tossou Jacques, Sègbo Julien, Atègbo Jean-Marc, Edorh Patrick Aléodjrodo, Sodipo Olufunkè, et al. "Hemostatic activity screening and skin toxicity of sap of Jatropha multifida L. (Euphorbiaceae) used in traditional medicine (Benin)." Asian Pacific Journal of Tropical Disease 2 (January 2012): S927—S932. http://dx.doi.org/10.1016/s2222-1808(12)60293-x.

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Aida, Fitri, Salman Salman, and Indah Laily Hilmi. "REVIEW : POTENSI PENGGUNAAN BAHAN ALAM SEBAGAI TERAPI KOMPLEMENTER ALTERNATIF PADA PENDERITA DEMAM BERDARAH DENGUE (DBD)." Journal of Pharmaceutical and Sciences 6, no. 1 (January 8, 2023): 82–89. http://dx.doi.org/10.36490/journal-jps.com.v6i1.5.

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DBD (Demam Berdarah Dengue) adalah penyakit yang banyak terjadi di negara beriklim tropis dan subtropis. Penyakit ini disebabkan oleh infeksi virus dengue (DENV) melalui gigitan nyamuk Aedes aegypty atau Aedes albopictus sebagai vektor primer. Angka kematian kasus DBD di Indonesia sejak Januari 2022 mengalami kenaikan sebanyak 89 kasus dibandingkan dengan tahun 2020. Faktor utama penyebab kematian pada kasus DBD yaitu defisiensi trombosit dan kebocoran plasma yang tidak segera ditangani Prinsip utama dalam tatalaksana penyakit DBD (Demam Berdarah Dengue) adalah terapi simptomatis serta terapi suportif seperti menaikkan nilai trombosit. Tujuan dari penelitian ini untuk mengetahui berbagai macam bahan alam yang berpotensi sebagai terapi komplementer pada penderita demam berdarah dengue (DBD).. Metode yang dilakukan yaitu kajian literatur (literature review). Hasil yang diperoleh yaitu kulit buah naga merah (Hylocereus polyrhizus), daun ubi jalar (Ipomoea batatas. L), daun dewa (Gynura pseudochina (L), rimpang temu hitam (Curcuma aeruginosa Roxb.), daun paku ekor kuda (Equisetum hyemale), , buah kurma (Phoenix dactylifera), kulit batang tanaman jarak cina (Jatropha multifida), daun papaya (Carica papaya L), daun patikan kebo (Euphorbia hirta), daun jambu biji (Psidium guajava), buah pala Wegio (Myristica fatua), dan daun Sambiloto (Andrographis paniculate) berpotensi sebagai terapi komplementer pada penderita DBD
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Mgbechi-Ezeri, J. U., O. J. Alabi, R. A. Naidu, and P. Lava Kumar. "First Report of the Occurrence of African cassava mosaic virus in a Mosaic Disease of Soybean in Nigeria." Plant Disease 92, no. 12 (December 2008): 1709. http://dx.doi.org/10.1094/pdis-92-12-1709b.

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African cassava mosaic virus (ACMV; genus Begomovirus, family Geminiviridae) is one of six viruses documented in cassava (Manihot esculenta Crantz.) plants showing cassava mosaic disease in sub-Saharan Africa (SSA). In addition to cassava, the natural host range of ACMV includes a few wild Manihot species, Jatropha multifida, and Ricinus communis L. in Euphorbiaceae, and Hewittia sublobata in Convolvulaceae. The experimental host range of ACMV includes Nicotiana sp. and Datura sp. in the Solanaceae (2). Recently, natural occurrence of ACMV was reported in Combretum confertum (Benth.), Leucana leucocephala (Lam.) De Witt, and Senna occidentalis (L.) Link belonging to Leguminasae from Nigeria (1,3). During reconnaissance studies conducted on soybean (Glycine max L. Merr.) in September and October of 2007 in the Ibadan (N = 19) and Benue (N = 23) regions and in February of 2008 in Ibadan (N = 16), we observed soybean showing yellow mosaic and mottling symptoms. Samples from these plants (N = 58) were tested by indirect ELISA and symptomatic leaves tested negative to Cucumber mosaic virus, Cowpea mottle virus, Southern bean mosaic virus, Tobacco ringspot virus, Soybean dwarf virus, Cowpea aphid-borne mosaic virus, Blackeye cowpea mosaic virus, Peanut mottle virus, and Broad bean mosaic virus, which have been documented in soybean in SSA. However, 8.6% of these samples (5 of 58) (one each from Ibadan and Benue in the 2007 survey and three from Ibadan in the 2008 survey) tested positive in triple-antibody sandwich-ELISA with a monoclonal antibody (SCR33) to ACMV. ELISA results were further confirmed by PCR with ACMV specific primers AL1/F and AR0/R that amplified a 987-bp DNA fragment corresponding to the intergenic region, AC-4 and AC-1 genes of DNA-A segment (4). The PCR product was cloned into pCR2.1 (Invitrogen, Carlsbad, CA) and three independent clones were sequenced in both orientations. Pairwise comparison of the derived consensus sequence (GenBank Accession No. EU367500) with corresponding ACMV sequence of ACMV isolate from Nigeria (GenBank Accession No. X17095) showed 98% identity at the nucleotide level. To further confirm the virus identity, complete nucleotide sequence of the DNA-A segment was determined by PCR amplification of viral DNA with four primers, cloning of overlapping products into pCR2.1 vector and sequencing. The derived sequence (2,781 nucleotides; GenBank Accession No. EU685385) was compared with the DNA sequences available at NCBI database using BLAST. This revealed 97% nucleotide sequence identity with ACMV-[NG:Ogo:90] (Accession No. AJ427910) and ACMV-[NG] (Accession No. X17095) from Nigeria. These results confirm the presence of ACMV in symptomatic soybean leaves. To our knowledge, this is the first report of soybean as a natural host of ACMV in SSA. On the basis of previous reports (1) and the results currently presented it seems that ACMV has a wide host range. References: (1) O. J. Alabi et al. Phytopathology (Abstr.) 97(suppl.):S3, 2007. (2) A. A. Brunt et al., eds. Plant viruses online: Descriptions and lists from the VIDE database. Version 20. Online publication, 1996. (3) F. O. Ogbe et al. Plant Dis. 90:548, 2006; (4) X. Zhou et al. J. Gen. Virol. 78:2101, 1997.
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Pananginan, Aldo J., Hariyadi Hariyadi, Vlagia Paat, and Yappi Saroinsong. "Formulasi Dan Uji Aktivitas Antibakteri Sediaan Sabun Cair Ekstrak Daun Jarak Tintir Jatropha Multifidi L." Biofarmasetikal Tropis 3, no. 1 (May 11, 2020): 148–58. http://dx.doi.org/10.55724/j.biofar.trop.v3i1.271.

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Sabun adalah produk yang dihasilkan dari reaksi antara asam lemak dengan basa kuat yang berfungsi untuk mencuci dan membersihkan lemak atau kotoran. Tujuan penelitian ini adalah untuk membuat sabun cair ekstrak daun jarak tintir dan melakukan pengujian aktivitas antibakteri sediaan sabun cair ekstrak daun jarak tintir terhadap bakteri Staphylococcus aureus. Penelitian ini merupakan eksperimen laboratorium. Metode yang digunakan adalah difusi sumuran. Hasil penelitian menunjukkan sediaan sabun cair ekstrak daun jarak tintir memiliki aktivitas antibakteri ditandai dengan terbentuknya zona hambat. Dari hasil penelitian dapat disimpulkan bawah formulasi sediaan sabun cair ekstrak daun jarak tintir dengan konsentrasi 20% dan 30% telah memenuhi persyaratan yang sesuai dengan standar yang ditetapkan SNI 06-4085-1996. Sedangkan pada konsentrasi 10% dalam uji bobot jenis tidak memenuhi persyaratan. Formulasi sediaan sabun cair ekstrak daun jarak tintir memiliki aktivitas antibakteri terhadap bakteri S. aureus yaitu pada konsentrasi 10% zona hambat 4.9 mm, konsentrasi 20% zona hambat 6.3 mm, dan konsentrasi 10% zona hambat 7.5 mm.
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Putri Kurnia Sari, Yani Lukmayani, and Kiki Mulkiya. "Studi Literatur Pemanfaatan Jarak Cina (Jatropha multifida L.) sebagai Antibakteri." Bandung Conference Series: Pharmacy 2, no. 2 (August 10, 2022). http://dx.doi.org/10.29313/bcsp.v2i2.4829.

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Abstract. The plants used were leaves and sap of Jatropha (Jatropha multifida L.). Jatropha contains flavonoids, alkaloids, tannins, saponins and phenolic acids, the compound content in Jatropha has an antibacterial function so that the leaf extract and sap of Jatropha (Jatropha multifida L.) can inhibit the growth of Staphylococcus aureus, Streptococcus mutans, Pseudomonas aeruginosa, Escherichia coli bacteria. The purpose of this study was to examine the use of Jatropha as an antibacterial, as well as to examine its active compounds. This research was conducted by literature study method using secondary data. Then, data analysis related to the antibacterial activity of castor leaves and latex was carried out. The results of this literature study indicate that the extract of Jatropha leaves and sap have potential as antibacterial. Antibacterial activity testing using disc diffusion and well diffusion methods. Jatropha leaf extract at 100% concentration was better than Jatropha sap in inhibiting Staphylococcus aureus. Water extract and ethanol extract of Jatropha leaves inhibited Staphylococcus aureus (Gram positive) compared to Pseudomonas aeruginosa (Gram negative). Meanwhile, methanol extract and ethyl acetate extract, as well as Jatropha curcas sap inhibited Escherichia coli (Gram negative) bacteria better than Staphylococcus aureus (Gram positive). Abstrak. Tanaman jarak cina, tanaman yang digunakan nya Daun dan getah Jarak cina (Jatropha multifida L.). Jarak cina mengandung flavonoid, alkaloid, tanin, saponin dan asam fenolik, kandungan senyawa pada jarak cina mempunyai fungsi sebagai antibakteri sehingga ekstrak daun dan getah jarak (Jatropha multifida L.) mampu menghambat pertumbuhan bakteri Staphylococcus aureus, Streptococcus mutans, Pseudomonas aeruginosa, Escherichia coli. Tujuan penelitian ini untuk mengkaji pemanfaatan jarak cina sebagai antibakteri, serta mengkaji senyawa aktifnya. Penelitian ini dilakukan dengan metode studi literatur menggunakan data sekunder. Kemudian data dianalisis terkait dengan aktivitas antibakteri daun dan getah jarak cina. Hasil studi literatur ini menunjukkan bahwa ekstrak daun dan getah jarak cina berpotensi sebagai antibakteri. Pengujian aktivitas antibakteri menggunakan metode difusi cakram dan difusi sumuran. Ekstrak daun jarak cina pada konsentrasi 100% lebih baik dari getah jarak cina dalam menghambat bakteri Staphylococcus aureus. Ekstrak air dan ekstrak etanol daun jarak cina menghambat bakteri Staphylococcus aureus (Gram positif) dari pada bakteri Pseudomonas aeruginosa (Gram negatif). Sedangkan ekstrak metanol dan ekstrak etil asetat, serta getah jarak cina menghambat bakteri Escherichia coli (Gram negatif) lebih baik dari pada bakteri Staphylococcus aureus (Gram positif).
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Anggita, Dwi, Yusriani Yusriani, Dian Amelia Abdi, and Vivin Desiani. "Effectiveness of Chinese Leaf Extract and Leaf Plants (Jatropha Multifida L.) As Antibacterial to Bacterial Growth Staphylococcus Aureus In Vitro." Window of Health : Jurnal Kesehatan, February 27, 2018, 29–33. http://dx.doi.org/10.33368/woh.v0i0.13.

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Jatropha multifida L. contains alkaloids, tannins, flavonoids, saponins and phenolic acids that differ from each part of the plant and the content of these substances is what makes L. multifida Jatropha has a function as an antibacterial so that the leaf extract and the gap of chinese distance ( Jatropha multifida L.) allegedly capable of inhibiting the growth of Staphylococcus aureus bacteria. The aim of this research was to know the effectivity of leaf extract and gum of Jatropha multifida L. to the growth of Staphylococcus aureus bacteria in vitro.Penelitian used true experimental post test design. Using disc diffusion method with concentration 25; 50; 75; and 100% v / v leaf and gum china distance. Positive control was used Clindamycin 5μg drip antibiotic paper disc. The data were analyzed descriptively. The result of the research showed the difference of different inhibition zone between treatments. In chinese leaf extracts showed different mean diameters, at concentrations of 25%, 50%, 75% with inhibit zone formed respectively 0 mm, 9.32 mm, and 17.48 mm and the highest inhibition zone at concentration of 100% with an average diameter of 22.24 mm. In the gap of chinese distance showed a different mean diameter, at concentrations of 25%, 50%, 75% with the inhibit zone formed respectively 16.08 mm, 18.15 mm, and 18.63 mm and the highest inhibition zone at a concentration of 100% with an average diameter of 21.91 mm. Clindamycin positive controls show an average inhibit zone of 23.31 mm. It was concluded that there was an effect of leaf extract and resin of chinese distance plant (Jatropha multifida L.) on growth of Staphylococcus aureus bacteria, and the best concentration was 100% concentration and almost closer to the inhibitory zone of Clindamycin antibiotics as positive control.
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Saptadi, Darmawan, Bambang Heliyanto, and Sudarsono Sudarsono. "Short Communication: Cross-species amplification of microsatellite markers developed for Jatropha curcas within five species of Jatropha." Biodiversitas Journal of Biological Diversity 21, no. 11 (October 8, 2020). http://dx.doi.org/10.13057/biodiv/d211111.

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Abstract. Saptadi D, Heliyanto B, Sudarsono. 2020. Short Communication: Cross-species amplification of microsatellite markers developed for Jatropha curcas within five species of Jatropha. Biodiversitas 21: 5072-5076. The transferability of SSR markers can be used to access the genetic diversity of related species. There are four close relatives of Jatropha curcas L in Indonesia, which can be utilized as a new diversity source through the interspecific crossing. This research was conducted to determine the ability of cross-species amplification of SSR markers developed from J. curcas to other Jatropha species (J. integerrima, J. multifida, J. gossypifolia, J. podagrica). It also investigated the relationship between these species. Out of 28 primers checked,11 primers showed cross-species amplification in all the species tested. Primer pairs EU099519, EU099528, and EU099525 have no transferability to other species. The overall percentage of polymorphism (PP) among all species tested was 95%, with the mean genetic similarity (GS) was 0.34. Least PP (17.35%) and highest GS (0.60) was found between pairs of J. podagrica and J. multifida. The correlation between the PP with GS was relatively high (0.75). The farthest and closest genetic distance was found between J. curcas/J. gossypifolia and J. podagrica/J. multifida, respectively. Further, selected primers from this study can be utilized in species differentiation, molecular identification of interspecific hybrids, and exploiting the genetic resource.
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Aiyelaagbe, OO, OF Fatunsin, BJ Oguntuase, CBA Adeniyi, and S. Gibbons. "Antimicrobial activity of Jatropha curcas L. and Jatropha multifida L. against bacteria and fungi s.t.d. organisms." Planta Medica 74, no. 09 (July 2008). http://dx.doi.org/10.1055/s-0028-1084021.

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Darmawi, Zakiah Heryawati Manaf, and Fahri Putranda. "DAYA HAMBAT GETAH JARAK CINA (Jatropha multifida L.) TERHADAP Staphylococcus aureus SECARA IN VITRO." Jurnal Medika Veterinaria 7, no. 2 (September 1, 2013). http://dx.doi.org/10.21157/j.med.vet..v7i2.2946.

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Penelitian ini bertujuan mengetahui pengaruh getah jarak cina (Jatropha multifida L.) terhadap pertumbuhan bakteri Staphylococcus aureus. Sampel yang digunakan dalam penelitian ini adalah Stapylococcus aureus dengan no Cat ATCC 25923 diperoleh dari Laboratorium Mikrobiologi Fakultas Kedokteran Hewan Universitas Syiah Kuala. Getah jarak cina diperoleh dari Desa Rukoh Kecamatan Syiah Kuala,diambil dengan cara menyayat batang jarak dan ditampung dalam tabung reaksi (Pyrex TM) sebanyak 50 ml. Penelitian ini dilakukan dengan 3 kali ulangan menggunakan konsentrasi 25; 50; 75; dan 100% v/v getah jarak cina. Kontrol positif digunakan kertas cakram antibiotik Vankomisin 30 µg. Daya hambat getah jarak cina menggunakan metode Kirby Bauer, dengan jumlah bakteri sesuai dengan standar Mc Farland I. Data yang diperoleh dianalisis secara deskriptif. Zona hambat yang terbentuk diukur dengan jangka sorong (Caliver TM). Hasil penelitian pada konsentrasi 25; 50; 75; dan 100% v/v zona hambat yang terbentuk masing-masing adalah 13; 13,5; 14,6; dan 15,7 mm. Zona hambat yang terbentuk dariantibiotik vankomisin 30 µg adalah 21 mm. Dari hasil penelitian dapat di simpulkan bahwa getah jarak cina (Jatropha multifida L.) dapat menghambat pertumbuhan Staphylococcus aureus.
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"Hemostatic Effect of Jatropha multifida L. (Euphorbiaceae) in Rats Having Coagulation Disorders." Journal of Applied Biology & Biotechnology, 2017. http://dx.doi.org/10.7324/jabb.2017.50504.

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Aiyelaagbe, OO, OF Fatunsin, BJ Oguntuase, BA Adeniyi, and S. Gibbons. "Antimicrobial activity of Jatropha multifida L. against bacteria and fungi s.t.d. organisms." Planta Medica 75, no. 09 (July 2009). http://dx.doi.org/10.1055/s-0029-1234652.

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Moharram, FA, MS Marzouk, EG Haggag, S. El-Batran, and RR Ibrahim. "Biological examination and novel biflavone di-C-glycosides from Jatropha multifida L. leaves." Planta Medica 73, no. 09 (2007). http://dx.doi.org/10.1055/s-2007-986830.

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43

Dec, Enderlei, and Denise Monique Dubet Da Silva Mouga. "Contribuição à morfologia polínica de plantas medicinais apícolas (Euphorbiaceae Juss. & Lamiaceae Martinov)." Acta Biológica Catarinense 1, no. 1 (July 18, 2014). http://dx.doi.org/10.21726/abc.v1i1.83.

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Em função da variabilidade dos tipos polínicos, sua descrição morfológica constitui suporte para diversas finalidades e estudos. Estão descritas neste trabalho 13 espécies polínicas de interesse apícola, sendo seis da família Euphorbiaceae (Euphorbia milii des Moul., E. pulcherrima Willd. ex Klotzsch, Jatropha curcas L., J. gossypiifolia L., J. multifida L. e Ricinus communis L.) e sete de Lamiaceae (Solenostemon scutellarioides (L.) Codd., Mentha x villosa Huds., Ocimum basilicum L., O. gratissimum L., Plectranthus grandis (L. H. Cramer) R. Willemse, P. neochilus Schlechter e Tetradenia riparia (Hochst.) Codd.). Os grãos foram preparados por acetólise, fotografados e caracterizados quanto a tamanho, forma, aberturas e ornamentação externa. A família Euphorbiaceae mostrou-se euripalinológica com grãos isopolares, de simetria radial, próximos da forma esferoidal, 3-colporados ou atremados (gênero Jatropha), com endoaberturas lalongadas em Euphorbia milii, E. pulcherrima e Ricinus communis, além de exina variando entre fina e espessa, bem como ornamentação reticulada, exceto para Ricinus (psilado). Em Lamiaceae, os grãos apresentaram-se isopolares, com simetria radial, formas que variavam de oblato a prolato, 6-colpados, com exina pouco variável, ornamentação sempre reticulada, sem endoaberturas, caracterizando uma família estenopalinológica. Palavras-chave: Estenopalinológica; euripalinológica; melissopalinologia; palinotaxonomia.
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Jean Robert Klotoé,. "In vitro evaluation of hemostatic properties of the sap of Jatropha multifida L. (Euphorbiaceae)." Journal of Medicinal Plants Research 6, no. 30 (August 8, 2012). http://dx.doi.org/10.5897/jmpr12.529.

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de Carvalho, Claudemir, Letícia Vieira Mariano, Vinícius S Negrão, Carolina Passarelli Gonçalves, and Maria Cristina Ribeiro Marcucci. "Phenols, flavonoids and antioxidant activity of Jatropha multifida L. collected in Pindamonhangaba, Sao Paulo State, Brazil." Journal of Analytical & Pharmaceutical Research 7, no. 5 (September 16, 2018). http://dx.doi.org/10.15406/japlr.2018.07.00286.

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Febrialdi, Akhyarnis. "Profil Beberapa Tanaman Obat di Hutan Sungai Telang Kabupaten Bungo." Jurnal Sains Agro 3, no. 1 (February 10, 2018). http://dx.doi.org/10.36355/jsa.v3i1.509.

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Keanekaragaman hutan merupakan potensi besar untuk dimanfaatkan oleh manusia, hutan kabupaten Bungo khusunya Desa sungai telang memiliki potensi keanekaragaman hutan yang dapat dimanfaatkan sebagai tanaman obat. penelitian ini ditujukan untuk mendapatkan Simplisia dan Skrining Fitokimia beberapa Tanaman obat di Hutan Desa sungai Telang Kabupaten Bungo.Tanaman obat yang diskrening dan dibuat simplisianya adalah tanaman disekitar yang tumbuh hutan yang dimanfaatkan oleh masyarakat sekitar hutan tersebut. Dari hasil ekplorasi terdapat 14 Jenis tanaman obat yang sangat sering digunakan oleh masyarakat yaitu Micania Micranta, Morinda citrifoli, Zingiber Casumounar, Physallis peruviann, Isotoma longiflora, M. leucadendra, Averrhoa bilimbi L, Lantana camara Linn, Impatiens balsamina L, Gynura procumbens, Daemonorops didymophyll, Casia Tora L, Jatropha multifida L, dan Oxalis Barrelieri. Dilakukan skrening fitokimia terhadap beberapa tanaman obat tersebut positif mengandung senyawa alkaloid, flavonoid, steroid, saponin dan Fenolik. Dengan terindentifikasinya kimia tanaman tersebut menambah potensi manfaat tanaman tersebut untuk diolah lebih lanjut menjadi obat modern dan pengayaan bahan ajar dan jurnal ilmiah.
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Maryam, St, Randi Pratama, Nurmaya Effendi, and Tadjuddin Naid. "ANALISIS AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOLIK DAUN YODIUM (Jatropha multifida L.) DENGAN METODE CUPRIC ION REDUCING ANTIOXIDANT CAPACITY (CUPRAC)." Jurnal Fitofarmaka Indonesia 2, no. 1 (August 5, 2016). http://dx.doi.org/10.33096/jffi.v2i1.185.

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48

"Antibacterial Activity Test of Jatropha multifida L. sap against Staphylococcus aureus and Methicillin Resistant Staphylococcus aureus (MRSA) in vitro." Indian Journal of Forensic Medicine & Toxicology, May 12, 2021. http://dx.doi.org/10.37506/ijfmt.v15i3.15611.

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., Juniarti, Aryenti ., Yuhernita ., Ernie Hernawati Poerwaningsih, Ahmad Aulia Jusuf, Hans Joachim Freisleben, and Mohamad Sadikin. "Effects of Methanolic Jatropha multifida L. Extract in Wound Healing Assessed by the Total Number of PMN Leukocytes and Fibroblasts." MAKARA of Science Series 16, no. 3 (March 20, 2013). http://dx.doi.org/10.7454/mss.v16i3.1479.

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50

Junaiddin, Junaiddin, Yulinda M. Bambungan, Baktianita Ratna Etnis, Untari Untari, Jenni Lilis S. Siagian, MPH Wahyuni, Hansen Maikel Su, M. Faizal Arianto, PH Livana, and Haeril Amir. "effect of the treatment with salve of topical tintir castor bark extract (jatropha multifida l) on the number of fibroblast, fibrin formation, and density of collagen in the wound healing process of the rat with the acute injury model." International journal of health sciences, April 5, 2022, 431–39. http://dx.doi.org/10.53730/ijhs.v6ns4.5527.

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The use of tradisional medicine in indonesia is part of the culture of the nation and much utilized by society. This study aimed to determine the effect of of the Treatment With Salve Of Topikal Tintir Castor Bark Extract (Jatropha Multifida L) on the Number of Fibroblast, Fibrin, Formation, And Density of Collagen In The Wound Healing Process of The Rat With The Acute Injury Model through excision diameter of 0.8 cm x 0.8 on the rat back. The research was conducted in the Animal laboratory of Hasanuddin University and the Education Animal Clinic(KHP), UNHAS. The method used in this research is the post-test control group design only. The sample consisted of 45 Wistar rats were divided into 3 groups: negative control (Vaseline), positive control (Oxcytetracilin 3%) and extract stem tintir distance. Data analysis using one way test anova. The study results indicated that on day 3(tree) the fibroblast showed an significant differences between groups of negative group and the tintir castro stem group of 10% (p=0.081) and there was an significant between the positive group and the tintir castro stem group of 10% (p=0.167); and on day 7(seven) and day 14, there was a difference but significant.
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