Relevant bibliographies by topics / IVF

Academic literature on the topic 'IVF'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 July 2024

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Journal articles on the topic "IVF"

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Miles, Harriet L., Paul L. Hofman, John Peek, Mark Harris, Dyanne Wilson, Elizabeth M. Robinson, Peter D. Gluckman, and Wayne S. Cutfield. "In Vitro Fertilization Improves Childhood Growth and Metabolism." Journal of Clinical Endocrinology & Metabolism 92, no. 9 (September 1, 2007): 3441–45. http://dx.doi.org/10.1210/jc.2006-2465.

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Abstract Background: There is limited information regarding the long-term outcome of children born after in vitro fertilization (IVF), although an increase in rare imprinted gene disorders such as Beckwith-Wiedemann syndrome has been reported. Methods: We recruited healthy, prepubertal children born at term after singleton pregnancy. The children in the study group were conceived using IVF with fresh embryo transfer, whereas controls were naturally conceived. Anthropometric measurements, bone age, dual-energy x-ray absorptiometry, fasting serum glucose, insulin, lipid profile, IGF-I and -II, and IGF-binding proteins 1, 2, and 3 were performed. Results: There were 69 IVF children aged 5.9 ± 0.2 yr and 71 control children aged 6.9 yr. IVF children were taller than controls when corrected for parents’ heights (height sd score of 1.05 ± 0.1 vs. 0.51 ± 0.11, P = 0.001) with higher levels of serum IGF-II (850 ± 24 vs. 773 ± 24 μg/liter, P = 0.03), higher IGF-I to IGF-binding protein 3 ratio (P = 0.04), and a trend toward higher IGF-I (105 ± 4 vs. 92 ± 4 μg/liter, P = 0.06). IVF children had higher high-density lipoprotein (1.67 ± 0.04 mmol/liter vs. 1.53 ± 0.04 mmol/liter, P = 0.02), lower triglycerides (0.65 ± 0.04 mmol/liter vs. 0.78 ± 0.04 mmol/liter, P = 0.02), and a lower total to high-density lipoprotein cholesterol ratio (2.58 vs. 2.86, P = 0.01). There were no differences in body composition. Conclusions: IVF children are taller with higher IGF-I and IGF-II levels and have a slightly more favorable lipid profile. We speculate that IVF results in epigenetic change through altered methylation of genes involved in growth and metabolism. IVF programs should consider long-term longitudinal follow-up of IVF offspring.
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Kim, S., S. H. Lee, J. H. Kim, Y. W. Jeong, O. J. Koo, S. Mi Park, E. G. Lee, et al. "46 ANTI-APOPTOTIC EFFECT OF INSULIN-LIKE GROWTH FACTOR-1 AND ITS RECEPTOR ON DEVELOPMENT OF PORCINE PRE-IMPLANTATION EMBRYOS PRODUCED BY IN VITRO FERTILIZATION AND SOMATIC CELL NUCLEAR TRANSFER." Reproduction, Fertility and Development 18, no. 2 (2006): 132. http://dx.doi.org/10.1071/rdv18n2ab46.

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Insulin-like growth factor (IGF)-I is a receptor-mediated autocrine and/or paracrine growth and/or survival factor for mammalian embryo development. It is known to promote the growth and development of mouse pre-implantation embryos. The present study was designed to investigate the effects of IGF-I (50 ng/mL), anti-IGF-I receptor (IGR-IR) antibody (0.05 �g/mL), and their combination on porcine pre-implantation embryo development. Furthermore, the mechanism underlying the embryotropic effects of IGF-I was evaluated by monitoring the incidence of apoptosis and expression of apoptosis-related genes. In both IVF and SCNT embryos, culturing with IGF-I increased the rate of blastocyst formation and this embryotropic effect was neutralized by culturing with IGF-I and anti-IGF-I receptor antibody. Significant effects on the development of blastocysts (P < 0.05) were found in IVF (16.9, 22.6, 9.3, and 13.5% for control, IGF-I, anti-IGF-IR antibody, and their combination, respectively) and SCNT (13.2, 21.0, 5.4, and 15.7%) embryos. Culturing IVF and SCNT embryos with IGF-I significantly increased the total number of cells in IVF blastocysts (58.3, 72.4, 41.1, and 55.2; P < 0.05), and SCNT blastocysts (49.2, 60.1, 35.2, and 43.1; P < 0.05), and it decreased the number of apoptotic nuclei in IVF blastocysts (3.9, 2.8, 5.5, and 3.9; P < 0.05) and SCNT blastocysts (4.6, 3.0, 6.1, and 4.9; P < 0.05). These effects of IGF-I were also neutralized by culturing with IGF-I along with anti-IGF-IR antibody. Expression of the anti-apoptotic Bcl-2 gene was increased, whereas expression of the pro-apoptotic Bax gene was decreased in both IVF and SCNT embryos cultured with IGF-I. In both IVF and SCNT embryos, anti-IGF-IR antibody along with IGF-I neutralized the effect of IGF-I on expression of Bcl-2 and Bax genes. In conclusion, the present study demonstrated that IGF-I through its specific receptors improved the developmental competence of IVF and SCNT embryos by decreasing the incidence of apoptosis and regulating apoptosis-related genes in porcine pre-implantation embryos. This study was supported by grants from the Korean MOST (Top Scientist Fellowship) and MAF (Biogreen 21 #20050301-034-443-026-01-00).
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O'Neill, C., and T. Stojanov. "240.Fertilisation in vitro causes precocious activation of transcription from the zygotic genome." Reproduction, Fertility and Development 16, no. 9 (2004): 240. http://dx.doi.org/10.1071/srb04abs240.

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In vitro fertilisation (IVF) may have long-term adverse effects on progeny. Infants conceived by in vitro fertilisation are more likely to be born small for dates and, in a mouse model, culture in vitro caused changes in neurological performance of progeny. Changes in the pattern of gene expression in IVF embryos have been detected, and these may be one cause of the long-term effects. This study investigates the effect of IVF on the ontogeny of onset of expression from the embryonic genome in the mouse. The expression of two markers for the onset of transcription (the transcription requiring complex (TRC) and hsp 70.1) was assessed in 2-cell embryos produced by IVF or fertilisation in situ (ISF). It was confirmed that the time from fertilisation to first cleavage was not different for IVF and ISF. Zygotes were cultured and at 1-hourly intervals those cleaved were 'picked off' (time 0 h after cleavage) and placed in groups of 10 in 10 μL of modified-HTF. The expression of the gene products was assayed at times after 'pick-off'. The proportion of embryos expressing TRC increased with time after cleavage (P�<�0.001). IVF embryos expressed it significantly earlier (P�<�0.01) than ISF embryos. Some IVF embryos expressed TRC immediately after cleavage and this was never found for ISF embryos. All IVF embryos were TRC-positive by 2.5 h after cleavage, while this did not occur until 4.5 h post cleavage for ISF. Hsp70.1 transcripts were first detected in IVF embryos 2 h after cleavage but not until 6 h after cleavage in ISF embryos (P�<�0.01). The onset of transcription at the 2-cell stage is currently thought to reflect major reorganization of the nucleosomal structure of DNA. Evidence for precocious onset of transcription may indicate that this fundamentally import process is changed following IVF, and warrants further investigation.
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Gleicher, Norbert, Sarah K. Darmon, Emanuela Molinari, Pasquale Patrizio, and David H. Barad. "Importance of IGF-I levels in IVF: potential relevance for growth hormone (GH) supplementation." Journal of Assisted Reproduction and Genetics 39, no. 2 (January 23, 2022): 409–16. http://dx.doi.org/10.1007/s10815-021-02379-8.

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Abstract Purpose Growth hormone (GH) supplementation in association with in vitro fertilization (IVF) is worldwide again increasing, even though study outcomes have been discrepant. Since GH acts via insulin-like growth factor-1 (IGF-1), its utilization in IVF would only seem to make sense with low IGF-1. We, therefore, determined whether IGF-I levels affect IVF outcomes. Methods Retrospectively, 302 consecutive first fresh, non-donor IVF cycles were studied, excluding patients on GH supplementation. Patients were divided into 3 subgroups: IGF-1 in lower 25th percentile (group A, < 132 ng/mL, n = 64); 25th–75th percentile (B, 133–202 ng/mL, n = 164), and upper 25th percentile (C, > 202 ng/mL, n = 74). IGF-1 was tested immunochemiluminometric with normal range at 78–270 ng/mL. Because of the study patients’ adverse selection and low pregnancy chances, the main outcome measure for the study was cycle cancellation. Secondary outcomes were oocyte numbers, embryos transferred, pregnancies, and live births. Results Group A was significantly older than B and C (P = 0.019). IGF-1 decreased with increasing age per year by 2.2 ± 0.65 ng/mL (P = 0.0007). FSH was best in group B and worst in A (trend, P = 0.085); AMH was best in B and worst in A (N.S.). Cycle cancellations were lowest in C (11.6%) and highest in A (25.0%; P = 0.042). This significance further improved with age adjustment (P = 0.021). Oocytes, embryo numbers, pregnancies, and live birth rates did not differ, though oocyte numbers trended highest in B. Conclusions Here presented results support the hypothesis that IGF-1 levels affect IVF outcomes. GH treatments, therefore, may be effective only with low IGF-1.
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Gagel, D. E., D. Ulrich, V. S. Pastor, and H. Kentenich. "IVF-Paare und IVF-Kinder." Reproduktionsmedizin 14, no. 1 (May 5, 1998): 31–40. http://dx.doi.org/10.1007/s004440050020.

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Malyugin, B. E., E. N. Panteleev, A. N. Bessarabov, D. F. Pokrovskiy, A. S. Semakina, and S. A. Abdullaeva. "Comparative Analysis of Refractive Result Predictability During Iridocapsular and Iridovitreal Fixation of Biplanar Intraocular Lens." Ophthalmology in Russia 15, no. 2 (July 5, 2018): 139–45. http://dx.doi.org/10.18008/1816-5095-2018-2-139-145.

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Purpose: to carry out a comparative analysis of refractive outcomes and features during preoperational calculation of the biplanar intraocular lens (IOL) with iridocapsular and iridovitreal fixation.Patients and methods. Study included the analysis IOL model RSP-3 implantation after phacoemulsification cataract surgery with subluxated lens grade 2. Analyzed 309 eyes of 304 patients with iridocapsular (n = 44) (ICF) and iridovitreal fixation (n = 265) (IVF). In both groups IOL power was calculated with use of A- constant (118.2) recommended by manufacturer. Mean period of examination was 6 months. To count optimized A-constant in both groups we used next data: IOL power and axial length before surgery, keratometry, spherical equivalent and IOL effective position during 6 months after surgery.Results. In group with ICF postoperative refraction was achieved ± 0,5 D in 10 cases (23%), in group IVF — in 29 cases (11%). Mean value of optimized A-constant for IOL model RSP-3 in groups with ICF and IVF were 117.2 ± 1.18 (114.0–120.8) and 116.9 ± 1,89 (109.6 до 123.6). There were no statistically significant difference between compared groups (p = 0.46).Conclusion. Use of A-constant recommended by manufacturer do not allow achieving target refraction in most cases. Mean values of biplanar IOL A-constant counted for ICF and IVF were 117,2 and 116,9 respectively, what should be taken into account during IOL power count, according to its fixation method.
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Lu, F., T. Luo, H. Sun, N. Li, X. Liu, L. Meng, J. Jiang, and D. Shi. "136 EFFECTS OF INSULIN-LIKE GROWTH FACTOR I (IGF-1) ON THE DEVELOPMENT AND APOPTOSIS OF PREIMPLANTATION BUFFALO (BUBALUS BUBALIS) EMBRYOS." Reproduction, Fertility and Development 25, no. 1 (2013): 215. http://dx.doi.org/10.1071/rdv25n1ab136.

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The aim of this study was to explore the effects of insulin-like growth factor-I (IGF-1) on the development and apoptosis of preimplantation buffalo (Bubalus bubalis) embryos derived from IVF or somatic cell nuclear transfer (SCNT) in order to improve the quality of in vitro embryo culture (IVC). Buffalo oocytes collected from ovaries at slaughter were cultured in the maturation medium (TCM-199 + 26.2 mmol L–1 NaHCO3 + 5 mmol L–1 HEPES + 5% FBS) for 22–24 h, and fertilized in vitro, or enucleated and reconstructed for SCNT. Embryos were then cultured in the culture medium (CM: TCM-199 + 3% FBS) supplemented with different concentrations of IGF-1. Blastocyst development was evaluated after 7 days of culture. A total of 1566 oocytes were used in this study. The experimental data were analyzed using two-way ANOVA, P < 0.05 was considered to be statistically significant. The results showed that the cleavage rates of IVF or SCNT embryos cultured with 0, 10, 50, or 100 ng mL–1 IGF-I, were not significantly different (P > 0.05). However, the blastocyst rate of IVF embryos cultured with 50 ng mL–1 IGF-1 was significantly increased compared to the 0 ng mL–1 group (35.1 v. 23.0%; P < 0.05), but not significantly different among the 0, 10, and 100 ng mL–1 groups (23.0 v. 28.2 and 26.5%; P > 0.05). In the same line, more SCNT embryos could develop to the blastocyst stage when cultured in the CM supplemented with 50 ng mL–1 IGF-I by comparison with the 0 ng mL–1 group (32.3 v. 20.2%; P < 0.05), but the blastocyst development decreased with 100 ng mL–1 (32.3 v. 21.4%; P < 0.05). Apoptosis and total cell number (TCN) of IVF/SCNT blastocysts were respectively detected by TUNEL or Hoechst 33342 staining. By comparison with the 0 ng mL–1 group, the TCN of IVF/SCNT blastocysts was significantly increased (IVF: 91.7 ± 6.9 v. 108.7 ± 3.9, SCNT: 76.3 ± 5.6 v. 92.8 ± 3.9; P < 0.05) and the apoptotic index was obviously decreased (IVF: 3.9 ± 0.7 v. 2.5 ± 0.7; 7.2 ± 0.5 v. 2.9 ± 0.5; P < 0.05) when the embryos were cultured in the CM with 50 ng mL–1 IGF-I. The result of RT-qPCR analysis showed that the mRNA expression level of the anti-apoptotic bcl-2 gene was distinctly enhanced, while the mRNA expression level of the pro-apoptotic bax gene was remarkably reduced in IVF/SCNT embryos cultured with 50 ng mL–1 IGF-I by comparison with the 0 ng mL–1 group (P < 0.05). These results demonstrated that supplementing CM with 50 ng mL–1 IGF-1 could improve the developmental competence of buffalo embryos, increase the TCN of blastocysts and decrease their apoptotic index, probably by down-regulating the mRNA level of pro-apoptotic bax gene and up-regulating the mRNA level of anti-apoptotic bcl-2 gene. This work was funded by the China High Technology Development Program (2011AA100607), China Natural Science Foundation (31072033), and Guangxi Science Foundation (2012GXNSFFA060004).
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Cela, Vito, Simona Daniele, Maria Elena Rosa Obino, Maria Ruggiero, Elisa Zappelli, Lorenzo Ceccarelli, Francesca Papini, et al. "Endometrial Dysbiosis Is Related to Inflammatory Factors in Women with Repeated Implantation Failure: A Pilot Study." Journal of Clinical Medicine 11, no. 9 (April 28, 2022): 2481. http://dx.doi.org/10.3390/jcm11092481.

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An abnormal endometrial microbiota has been suggested to impair the process of embryo implantation, thus leading to repeated implantation failure (RIF) in women undergoing in vitro fertilization (IVF). However, the molecular mechanisms linking uterine microbiota and IVF out-comes are still an open question. The aim of this cohort study was to outline the relationship between endometrial microbiota, inflammation and IVF outcomes. To this purpose, endometrial microbiota and selected components of the “cytokine network” were analyzed in women presenting RIF and divided between eubiosis and dysbiosis groups, according to the percentage of endometrial lactobacilli (≥90% or <90%, respectively). The Dysbiosis group presented significantly higher tissue concentrations of the inflammatory markers (IL-6, IL-1β, HIF-1α and COX-2) and significantly lower levels of the anti-inflammatory/well-being factors, IL-10 and IGF-1, with respect to women with eubiosis. Moreover, the Lactobacillus percentage was negatively related to the concentrations of the inflammatory molecules and positively related to IL-10/IGF-1. Interestingly, the number of IVF attempts was directly related to the levels of the inflammatory factors COX-2, IL-1β and HIF-1α in the eubiosis group. Overall, endometrial dysbiosis was demonstrated to be associated with inflammation-related endometrial changes affecting the process of embryo implantation, underlining the importance of assessing uterine microbiota in patients undergoing IVF.
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Garcia Velasco, Juan Antonio, and Emre Seli. "IVF." Current Opinion in Obstetrics and Gynecology 27, no. 3 (June 2015): 165–66. http://dx.doi.org/10.1097/gco.0000000000000178.

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Seli, Emre, and Juan Garcia-Velasco. "IVF." Current Opinion in Obstetrics and Gynecology 28, no. 3 (June 2016): 149–50. http://dx.doi.org/10.1097/gco.0000000000000275.

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Dissertations / Theses on the topic "IVF"

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Mansour, Ragaa Taha Ahmed. "Optimizing IVF results." Maastricht : Maastricht : Universiteit Maastricht ; University Library, Maastricht University [Host], 2003. http://arno.unimaas.nl/show.cgi?fid=6122.

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Boden, Jane. "When IVF treatment fails." Thesis, University of Hull, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419766.

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Little is known of how patients cope when treatment fails and they are faced with the prospect of life without their 'own' child. Initial observations suggest that for some, the effects can be traumatic and long lasting. Thirty-five {narrative' interviews were carried out with patients and partners for whom treatment had failed five years previously. Transcripts were subject to formal thematic analysis. A significant factor, which emerged from a formal analysis of transcripts, was the role of 'hope'. Treatment offers the hope that they may have a child and this provides the motivation for treatment; alongside the urgent need to pre-empt future regrets. The failure of treatment does little to dent this hope as long as there is 'another chance', but not so when treatment is discontinued. Once the support provided by hope is removed, patients can struggle to make sense of their lives and patients may seek and need (but not receive) psychological support. A significant and unexpected finding was anger and the widespread feeling amongst patients that they had been abandoned at this time. It would appear that some form of closure regarding the ending of treatment is required. Research found some couples are able to reinvest in life goals and re-establish their relationships; however, there were a significant proportion of couples who were still struggling five years after their last attempt, to adapt to life without the child they had anticipated. Many couples move onto alternative options, i.e., adoption, however, not all couples recover from the trauma of the inability to parent at will and some relationships break down. There is an irrefutable lack of psychological support offered to couples going through assisted conception, and findings suggest indisputably that more support should be offered on a regular basis to couples going through this process and beyond
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Hammarberg, Karin. "Women's experience of IVF treatment /." Connect to thesis, 1998. http://eprints.unimelb.edu.au/archive/00002870.

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Holding, Jessica Anne. "IVF children's understanding of biological inheritance /." Title page, abstract and contents only, 2001. http://web4.library.adelaide.edu.au/theses/09SS.PS/09ss.psh7278.pdf.

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Veleva, Z. (Zdravka). "Factors affecting the outcome of IVF/ICSI." Doctoral thesis, University of Oulu, 2008. http://urn.fi/urn:isbn:9789514288838.

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Abstract Fertility declines with advancing age and the number of couples seeking infertility treatment at an older age is constantly increasing. A top quality embryo is believed to have the highest potential for implantation and development into a child. A better understanding of the relative importance of patient and treatment characteristics and of embryo quality could help to optimise the existing therapeutic schemes and the safety of in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI). In this work, databases of five Finnish infertility clinics were studied retrospectively. Data on treatments performed in the years 1994–2005 were collected. A total of 19,000 treatment cycles were analysed. Special attention was paid to the relative significance of the transfer of top quality embryos with regards to pregnancy, miscarriage, live birth and cost of treatment in the general IVF/ICSI patient population and in groups with expected poor outcome. The results showed that the transfer of a top quality embryo is associated with a better chance of pregnancy and live birth. However, it does not diminish the probability of miscarriage. Both low and high BMI increase the miscarriage rate. Advancing age and a positive history of previous miscarriages are also associated with a higher probability of miscarriage. In addition, the need for hormonal substitution in cases of frozen-embryo transfer is a risk factor of miscarriage, probably because of suboptimal endometrial function. Since the transfer of several embryos leads to multiple pregnancies, which are associated with a high risk of maternal and fetal complications, elective single embryo transfer (eSET) of a top quality embryo allows all additional good quality embryos to be frozen and transferred later in frozen-thawed embryo transfer cycles. The present work demonstrates that eSET is a safe treatment strategy at least until the age of 40. However, it might not be performed in women with fewer than four collected oocytes, since the prognosis might remain poor even if the response is improved in a following cycle. When eSET is applied routinely and on a large scale, it diminishes treatment costs while increasing the number of deliveries occurring at term, making IVF/ICSI at the same time safer and more affordable even to patients without access to reimbursed IVF treatment.
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Coates, Alison. "Optimizing IVF outcomes in the genomics era." Thesis, University of Kent, 2017. https://kar.kent.ac.uk/64357/.

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In order to optimize pregnancy rates during IVF cycle, we have to grow embryos in such a way to allow them to reach their full potential in-vitro. As IVF has evolved since the first live birth in 1978, culture conditions have improved and we have reached a stage where embryos can thrive to the blastocyst stage in-vitro if programmed to do so. IVF cycles typically produce multiple embryos during one cycle. Establishing which embryo has a higher potential to result in a live birth than its sibling embryos has been attempted over the last 30 years by using non-invasive and invasive techniques. Methods to choose which embryo to transfer range from basic morphology to establishing ploidy status of each embryo by biopsy. Aneuploidy is the most common cause of implantation failure and miscarriage in human reproduction and increases with maternal age, however all maternal ages exhibit varying degrees of embryonic aneuploidy. While some non-invasive techniques have shown promise in predicting which embryos have the highest implantation potential, the only way currently to establish ploidy status of embryos in the embryology lab is to biopsy, then assay embryonic cells before transfer. To improve IVF success, original studies derived from retrospective analysis of clinic data, or prospectively designed studies are essential and a number of fundamental biological questions pertaining to chromosome abnormalities and their relationship to IVF embryo development remain unanswered. The overall aim of this thesis was thus to provide further insight into the cytogenetic basis of early human development by pursuit of the following specific aims: (1) To test the hypothesis that we can predict aneuploidy levels in human IVF embryos without embryo biopsy for PGS by analysis of basic morphokinetic criteria and spent media from cell free embryonic DNA, (2) to test the hypothesis that the ICSI technique may create aneuploidy in embryos, (3) to establish novel patient populations that may benefit from the use of PGS, specifically male factor infertility patients and young oocyte donors, (4) conducting a randomized controlled trial (RCT) to establish the optimal transfer strategy (fresh vs frozen) for euploid embryos in patients using their own oocytes,(5) to test the hypothesis that identifying mosaic embryos among a cohort of embryos could increase live birth rates and reduce miscarriage rates by avoiding these embryos for transfer and (6) to use the data generated from PGS/IVF cycles to provide a framework for creating realistic expectations for patients planning for their fertility future. The conclusions of each aim were as follows: I demonstrated that poorer quality embryos showed an increased rate of aneuploidy but not large enough to predict aneuploidy for each individual embryo. Analysis of cell free DNA in spent culture media is at its early stages of development, but the study presented in this chapter using a novel WGA technique, showed that there is potential for its future use as a non-invasive PGS method. I found that aneuploidy rates were similar in embryos generated from normal sperm whether they were created using ICSI or standard insemination using a donor oocyte model to minimize the maternal age effect (aneuploidy rates of 21% for standard IVF vs 23% for ICSI. P= > 0.05 NS) concluding that the ICSI technique does not create embryonic aneuploidy. Donor oocyte recipients (average age of donor 25) benefited from PGS in cryopreserved embryo transfer cycles by significantly increasing live birth rates per embryo from 36% with no PGS to 59% per PGS screened embryo (p=0.0008). Male factor infertility patients presenting with oligozoospermia, were shown to exhibit a significantly higher incidence of sex chromosome abnormalities in pre-implantation embryos compared to patients with normal sperm using ICSI (6.1% for oligozoospermic samples vs 1.6% for normal semen samples. P=0.0007). Both of these patient groups could benefit from offering PGS as part of their IVF cycle. The RCT showed that freeze all cycles had higher live birth rates than fresh cycles (77% of frozen embryo transfers vs 59% of fresh embryo transfers. P=0.04). When comparing transfer of embryos screened by NGS with those screened by aCGH, the conclusion in the relatively small subset of patients was that live birth rates for embryos screened with aCGH and NGS appear to be similar, with a 2% trend in favor of NGS (61% aCGH vs 63% NGS live born offspring per embryo transferred. P= > 0.05 NS). Lastly, the retrospective analysis of data using PGS cycles to calculate how many oocytes are required to create one euploid blastocyst depending on maternal age, resulted in a useful tool to advise patients on how many cycles of IVF they may need to complete their family. Taken together therefore, this thesis provides fundamental insight into the chromosomal basis of early human development, introduces new referral categories for PGS and informs the practical use of IVF/PGS in the future.
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Emery, Josephine Angela. "Psychological aspects of IVF : a prospective study." Thesis, University of Manchester, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685728.

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Andze, Ramune [Verfasser], Joseph [Akademischer Betreuer] Neulen, and Ivo [Akademischer Betreuer] Meinhold-Heerlein. "Einfluss der Adipositas auf IVF- und ICSI-Ergebnisse / Ramune Andze ; Joseph Neulen, Ivo Meinhold-Heerlein." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://d-nb.info/1130871479/34.

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Ojala, Petra, and Emelie Svensson. "Ett förlorat ögonblick : Kvinnors upplevelser under IVF-behandlingen." Thesis, Högskolan i Borås, Institutionen för Vårdvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-20886.

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Ungefär vart femte par i fertil ålder drabbas av ofrivillig barnlöshet och många av dem genomgår då in vitro-fertilisering (IVF). Infertilitet och IVF- behandling kan leda till att upplevelsen av sig själv och sitt förhållningssätt till andra förändras och detta kan medföra ett lidande för kvinnorna. Antalet IVF behandlingar ökar för varje år och syftet med examensarbetet är att belysa kvinnors upplevelse under IVF- behandling. Genom en ökad kunskap kan vårdpersonal på ett mer tillfredställande sätt möta kvinnor som genomgår fertilitetsbehandlingar och minska deras lidande. Den valda metoden är en kvalitativ innehållsanalys och litteraturen är begränsad till självbiografier, som ger en mer detaljrik inblick i kvinnornas livsvärld. Resultatet är sammanställt efter en analys av fyra biografier och bygger på fyra huvudteman, ”Att förlora kontrollen”, ”Relationen till andra”, ”Ett intrång i kroppen” och ”Väntan”. Behandlingen medförde en stor psykisk och fysisk påfrestning för kvinnorna. De upplevde en kontrollförlust då IVF blev deras identitet och att kontrollen över den egna kroppen och känslolivet delvis gick förlorad. Kvinnornas relation till andra påverkades negativt, särskilt relationen till den egna partnern då samlivet förändrades. Vidare fanns det moment under behandlingen som kvinnor upplevde som ett intrång i den egna kroppen och som i de flesta fall var förenat med smärta och obehag. Det som upplevdes som mest påfrestande var väntan efter att ett embryo förts tillbaka till kvinnan och tills det att ett graviditetstest kunde göras, och utfallet av behandlingen konstateras. Upplevelsen av behandlingen är sammankopplad med upplevelsen av infertilitet och det uppstod stundtals svårigheter att skilja dessa åt. Resultatet visade att vårdpersonalen kunde göra skillnad för kvinnornas upplevelse av behandlingen genom att visa engagemang och medmänsklig kärlek.
Program: Sjuksköterskeutbildning
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Pertoldová, Stanislava. "Vybrané faktory ovlivňující úspěšnost přenosu embryí po IVF." Master's thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-256764.

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Assisted reproduction is a field of medicine that deals with infertility tretment. Ongoing improvements of laboratory technology as well as ongoing evolving scientific research within IVF research,including experimental embryology in routine practice is contributing in a steady improvement of success rates of assisted reproduction. This thesis is primarily based on data and information provided by the laboratory of assisted reproduction of GEST IVF Ltd.clinic in Prague,which was collected during the year 2015. This data was analyzed and investigated to verify the effect of selected factors on the success of the treatment. In This thesis we have not used any personal data of patients in accordance with the legislation act.296/2008Sb. The results show clear evidence between the treatment success rate and patients age within all evaluated parameters. The fundametal hypothesis of interdependence of embryo quality on the further development of the embryo after the transfer was comfirmed. Conversely, the timeframe for embryo cultivation is not an important parameter of success. Commonly used cuture media also did not show a significant impact on treatment outcome. Statistical calculations also confirmed surprisingly significant differences in embryo transfer after 72 hours development and 120 hours development for women ever 35 years. Transfers of younger embryos appears to be more convenient for women over 35 years.
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Books on the topic "IVF"

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Van Blerkom, Jonathan, and Linda Gregory, eds. Essential IVF. Boston, MA: Springer US, 2004. http://dx.doi.org/10.1007/978-1-4419-8955-0.

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Liang, Lifang. Acupuncture & IVF: Increase IVF success by 40-60%. Boulder, CO: Blue Poppy Press, 2003.

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Throsby, Karen. When IVF Fails. London: Palgrave Macmillan UK, 2004. http://dx.doi.org/10.1057/9780230505704.

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Ferber, Sarah, Nicola J. Marks, and Vera Mackie. IVF and Assisted Reproduction. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-7895-3.

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IVF: A patient's guide. Portland, Or: Get It Right, 2010.

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Infertile Couples and IVF. Saarbrücken: LAP LAMBERT Academic Publishing, 2014.

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The ethics of IVF. London: Mowbray, 1995.

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Montag, Markus H. M., and Dean E. Morbeck, eds. Principles of IVF Laboratory Practice. Cambridge: Cambridge University Press, 2017. http://dx.doi.org/10.1017/9781316569238.

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Hammarberg, Karin. IVF and Beyond For Dummies. Hoboken: John Wiley & Sons, 2010.

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Sher, Geoffrey. The journey to IVF success. [United States]: Sher Institute for Reproductive Medicine, 2001.

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Book chapters on the topic "IVF"

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Tan, Justin, and Seang Lin Tan. "Natural Cycle IVF/Modified Natural Cycle IVF and Natural Cycle IVF/IVM." In Textbook of Assisted Reproduction, 149–55. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-2377-9_17.

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Boltz, Marie, Holly Rau, Paula Williams, Holly Rau, Paula Williams, Jane Upton, Jos A. Bosch, et al. "IVF." In Encyclopedia of Behavioral Medicine, 1124. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_100935.

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Prados, Nicolas, and Alex C. Varghese. "IVF Workstations." In Practical Manual of In Vitro Fertilization, 71–78. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-1780-5_10.

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Ioscovich, Alexander, Yair Binyamin, and Daniel Shatalin. "IVF Anaesthesia." In Textbook of Assisted Reproductive Techniques, 706–13. 6th ed. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003268611-62.

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Meyer, Cornelia G. A. "Conventional IVF." In Textbook of Assisted Reproduction, 779–86. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-2377-9_86.

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Tuffin, Keith. "IVF failure." In Considering Counter-Narratives, 83–91. Amsterdam: John Benjamins Publishing Company, 2004. http://dx.doi.org/10.1075/sin.4.12tuf.

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Prados, Nicolas, and Alex C. Varghese. "IVF Workstations." In Building and Managing an IVF Laboratory, 59–72. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8366-3_5.

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Allan, Helen, and Ginny Mounce. "IVF parents." In The Transition to Parenthood after IVF, 164–93. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003231417-7.

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von Wolff, Michael. "Natural Cycle IVF and Minimal Stimulation IVF Worldwide." In Natural Cycle and Minimal Stimulation IVF, 245–48. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-97571-5_25.

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Takhar, Jennifer. "IVF survivorship, the IVF memoir and reproductive activism." In Transhumanisms and Biotechnologies in Consumer Society, 62–74. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003295594-4.

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Conference papers on the topic "IVF"

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Opsenica Kostic, Jelena, Milica Mitrovic, and Damjana Panic. "THE EXPERIENCE OF INFERTILITY AND QUALITY OF LIFE OF WOMEN UNDERGOING THE IVF PROCESS – A STUDY IN SERBIA." In International Psychological Applications Conference and Trends. inScience Press, 2021. http://dx.doi.org/10.36315/2021inpact005.

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"Studies have shown that women facing infertility and undergoing the IVF process generally belong to the mentally healthy group of the population. However, their stress level and emotional reactions vary significantly. Besides, there are women who report higher anxiety and/or depression levels up to six months after an (unsuccessful) IVF process. The aim of this study is to determine the perception of the infertility experience and the functioning of domains particularly affected by overcoming infertility through IVF. Fourteen women were excluded from the study sample due to their secondary infertility: 9 women had already had a child conceived though IVF and 5 had conceived naturally – these respondents have a successful experience of overcoming infertility, as they do not face the possibility of remaining involuntarily childless. The final sample was comprised of 149 women, 23 to 45 years of age (M=35,50, SD=4,48). For 83,9% of the women, the ongoing IVF procedure was the first (38,3), the second (25,5) or the third (20,1) attempt, while the rest of respondents were going though IVF for the fourth to the eighth time. Infertility is considered the worst experience of their life by 67,8% of the respondents. 95,3% of the respondents in the study want psychological counseling, which is not an integral part of the IVF process in Serbia and thus not covered by the national health insurance. The “Fertility quality of Life” (FertiQoL; Boivin, Takefman and Braverman, 2011) Questionnaire was used for the assessment of quality of life. A one sample t-test shows statistically significant differences in experiencing difficulties in the observed domains. The respondents have the lowest scores on the Emotional subscale, meaning that the most pronounced feature is the impact of negative emotions (e.g., jealousy and resentment, sadness, depression) on quality of life. The score on the Social subscale is highest, which means that social interactions have not significantly been affected by fertility problems. In conclusion, the infertility experience is highly stressful for a significant number of women and they are in need of psychological support, especially for overcoming negative emotions. This can be done by defining a new way of life filled with contentment, one that is in accordance with their value systems, despite their experience of infertility."
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Goncalves, D. E., J. D. Sanjuan, S. E. Di´az, and M. Pacheco. "Experimental Construction of Reduced Mathematical Models of Rotating Equipments in Operation." In ASME Turbo Expo 2003, collocated with the 2003 International Joint Power Generation Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/gt2003-38753.

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An experimental method is proposed to obtain simplified mathematical models of rotating equipment systems. The Instrumental Variable Filter (IVF) method is applied to estimate mass, damping and stiffness force coefficients within a frequency range, through experimental measurements. This method is based on the least squares approximation technique and it uses analytical weight functions to reduce the effect of noise in the measurements. The experimental data is obtained for different configurations of rotating equipments, which consist of rigid wheels, a flexible shaft supported by bushing bearings, an electrical motor, a base-plate, and a concrete foundation. Frequency response functions (FRF) were obtained by impact excitation techniques. In the tests, the unbalanced response measurements were compared with the ones predicted by the IVF model. The method allows the study of mass, damping and stiffness force coefficients as a function of excitation frequency. Linearities and non-linearities of phenomena are identified, and the method sums up all the individual components into a definition for the system. The tests were conducted by operating, or not, the motor, in order to evaluate the IVF method in both cases. The high correlation between the IVF (FRF, and unbalance responses) and the actual measurements of the FRF and unbalance responses, shows that the method generates useful mathematical models of dynamic systems, that can have industrial applications. Modal analysis methods were used to compare the natural frequencies and the damping ratios, obtained by dynamic coefficients estimation.
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Uyar, Asli, Ayse Bener, H. Nadir Ciray, and Mustafa Bahceci. "Bayesian Networks for Predicting IVF Blastocyst Development." In 2010 20th International Conference on Pattern Recognition (ICPR). IEEE, 2010. http://dx.doi.org/10.1109/icpr.2010.679.

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Joshi, M. A., S. C. Mehrotra, M. R. Jathar, and Anuradha Shewale. "Distributed temperature monitoring system for IVF laboratory." In 2011 3rd International Conference on Electronics Computer Technology (ICECT). IEEE, 2011. http://dx.doi.org/10.1109/icectech.2011.5941904.

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Ahmad Wazir, Norhidayah, Shazleen Saadon, and Anita Ramli. "New Formulation of Ultra-Low Ift Surfactant for Potential Eor Application." In Offshore Technology Conference Asia. OTC, 2022. http://dx.doi.org/10.4043/31449-ms.

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Abstract The paper discussed the development of an Ultra-Low Interfacial Tension (IFT) foaming surfactant based on a combination of improved as-synthesized surfactant (CBH) consist of as-synthesized oleic amido propyl betaine with mixtures of co-solvents and PETRONAS’ in-house patented foaming-based surfactant (IVF) which consist of amphoteric and anionic surfactant; as well as the performance evaluation of the surfactant in Enhanced Oil Revery (EOR) application. CBH and PETRONAS (IVF) foam-based surfactants were used in the formulation as ultra-low IFT and foaming components, respectively. The surfactant's development has been highlighted, and the findings have been discussed in detail. Due to the good foaming and IFT output at ultra-low levels, the combination of 0.3wt.% IVF and CBH at a ratio of 2: 8 was suggested. The addition of a non-ionic scleroglucan polymer from the polysaccharide group was chosen to study the stabilizing effect to the foam and the ultra-low IFT value of the formulation. Based on the findings, the presence of scleroglucan in the formulation has a significant effect on the performance of IFT and foam of the formulation when compared to the original formulation.
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Razali, Norzafirah, Ivy Ching Hsia Chai, Arif Azhan A Manap, and M. Iqbal Mahamad Amir. "Enhanced Foam Stability Using Nanoparticle in High Salinity High Temperature Condition for Eor Application." In Abu Dhabi International Petroleum Exhibition & Conference. SPE, 2021. http://dx.doi.org/10.2118/208196-ms.

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Abstract The capability of commercial nanoparticles to perform as foam stabilizer were investigated at reservoir temperature of 96°C. Al2O3, Fe3O4, Co3O4, CuO, MgO, NiO, ZrO2, ZnO and SiO2 nanoparticles that were characterized using XRD, FTIR, FESEM-EDX, TEM and PSA, were blended in the in-house formulated surfactant named IVF respectively at a particular ratio. The test was performed with and without the presence of reservoir crude oil. Results showed that formulation with nanoparticles enhanced foam stability by having longer foam half-life than the IVF surfactant alone, especially in the absence of oil. Only SiO2 nanoparticles were observed to have improved the foam stability in both test conditions. The unique properties of SiO2 as a semi-metal oxide material may have contributed to the insensitivity of SiO2 nanoparticle towards crude oil which is known as a foam destabilizer. The physical barrier that was formed by SiO2 nanoparticles at the foam lamella were probably unaffected by the presence of crude oil, thus allowing the foams to maintain its stability. In thermal stability tests, we observed the instability of all nanoparticles in the IVF formulation at 96°C. Nanoparticles were observed to have separated and settled within 24 hours. Therefore, surface modification of nanoparticle was done to establish steric stabilization by grafting macro-molecule of polymer onto the surface of SiO2. This in-house developed polymer grafted silica nanoparticles are named ZPG nanoparticles. The ZPG nanoparticles passed the thermal stability test at 96°C for a duration of 3 months. In the foam wetness analysis, ZPG nanoparticles were observed to have produced more wet foams than IVF formulation alone, indicating that ZPG is suitable to be used as foam stabilizer for EOR process as it showed catalytic behaviour and thermally well-stable at reservoir temperature.
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Ivanova, A. D., M. A. Tofilo, and I. V. Volodyaev. "FALSE POSITIVE DIAGNOSIS OF CHROMOSOMAL MOSAICISM IN IVF: FACTORS OF INFLUENCE." In NOVEL TECHNOLOGIES IN MEDICINE, BIOLOGY, PHARMACOLOGY AND ECOLOGY. Institute of information technology, 2022. http://dx.doi.org/10.47501/978-5-6044060-2-1.163-170.

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The article discusses the influence of laboratory factors on the occurrence of artifact noise on NGS profiles, which can be falsely interpreted as chromosomal mosaicism of preimplantation embryos in IVF clinical practice.
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Gasparov, A. S., E. D. Dubinskaya, N. V. Dmitrieva, S. N. Kolesnikova, and I. V. Holban. "The effectiveness of the new intraovarial autoplasmotherapy technology in patients with low ovarian reserve." In Scientific achievements of the third millennium. SPC "LJournal", 2021. http://dx.doi.org/10.18411/scienceconf-09-2021-03.

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In this study, the authors presented the results of intraovarial autoplasmotherapy (PRP – platelet rich plasma) in 80 patients suffering from low ovarian reserve, “poor response” in IVF programs and ineffective IVF attempts in the anamnesis. The 1st group included 40 women who underwent intraovarial PRP by means of using stop-point navigation technology; the 2nd group included 40 women who received PRP without using stop-point navigation technology. The obtained data convincingly demonstrate that PRP with the use of stop-point navigation technology has a better effect on the ovarian function activation (an increase in anti-muller hormone (AMH), an increase in the number of antral follicles (CAF), an increase in estradiol, a decrease in follicle-stimulating hormone (FSH)), compared with PRP without the use of stop-point navigation technology.
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Gasparov, A. S., E. D. Dubinskaya, N. V. Dmitrieva, S. N. Kolesnikova, and I. V. Holban. "The effectiveness of the new intraovarial autoplasmotherapy technology in patients with low ovarian reserve." In Scientific achievements of the third millennium. SPC "LJournal", 2021. http://dx.doi.org/10.18411/scienceconf-09-2021-03.

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In this study, the authors presented the results of intraovarial autoplasmotherapy (PRP – platelet rich plasma) in 80 patients suffering from low ovarian reserve, “poor response” in IVF programs and ineffective IVF attempts in the anamnesis. The 1st group included 40 women who underwent intraovarial PRP by means of using stop-point navigation technology; the 2nd group included 40 women who received PRP without using stop-point navigation technology. The obtained data convincingly demonstrate that PRP with the use of stop-point navigation technology has a better effect on the ovarian function activation (an increase in anti-muller hormone (AMH), an increase in the number of antral follicles (CAF), an increase in estradiol, a decrease in follicle-stimulating hormone (FSH)), compared with PRP without the use of stop-point navigation technology.
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Wang, Fei, Senyue Hao, Kibeom Park, Ali Ahmady, and Chao Zhou. "Noninvasive Evaluation of Mouse Embryo Development Using Time-lapse Optical Coherence Microscopy." In Optical Coherence Tomography. Washington, D.C.: Optica Publishing Group, 2024. http://dx.doi.org/10.1364/oct.2024.cs5e.3.

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Optical coherence microscopy (OCM) offers volumetric imaging for non-invasive evaluation of embryo quality in in-vitro fertilization (IVF). Time-lapse OCM images of cryopreserved mouse embryos revealed development milestones, blastocyst grading, and stage timing inside the incubator.
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Reports on the topic "IVF"

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Zhang, Jianeng, Chong Wang, Huanhuan Zhang, and Yan Zhou. Cleavage and blastocyst embryo sequential transfer and IVF outcome. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2021. http://dx.doi.org/10.37766/inplasy2021.8.0019.

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Yang, Liu, Fuxiang Liang, Rongyan Zhu, Lifei Li, Liyan Wang, Xuehong Zhang, and Liang Yao. Efficacy of intracytoplasmic sperm injection in women with non-male factor infertility: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2023. http://dx.doi.org/10.37766/inplasy2023.4.0003.

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Review question / Objective: This meta-analysis aims to evaluate whether intracytoplasmic sperm injection (ICSI) improved reproductive outcomes for non-male factor infertility versus in vitro fertilization (IVF). Condition being studied: The use of ICSI has increased dramatically in recent years and is being applied for indications other than male factor infertility. However, despite its increased use, there is no clear evidence of the benefit of using ICSI over conventional IVF for non-male factor infertility. Eligibility criteria: Studies will be excluded if one of the following conditions is met: (1) unqualified male perm count and motility; (2) rescued ICSI; (3) non-RCTs of study design; (4) a significant amount of research data is missing or not available.
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Ingilizova, Gergana, Ivan Kostov, Emil Kovachev, Viktoria Necheva, and Svetlozar Slavov. Preimplantation Embryo Quality in Patients with Low Ovarian Reserve: Study of 72 IVF/ICSI Treatment Cycles. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, August 2020. http://dx.doi.org/10.7546/crabs.2020.08.14.

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Shi, Yanbin, Yang Shi, Guiyuan He, Guang Wang, Hongbo Liu, and Xiaoguang Shao. Association of ADAMTS proteoglycanases downregulation with IVF-ET outcomes in patients with polycystic ovary syndrome: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0115.

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Li, Sixuan, Ying Ye, Zhaoxing Chen, Mao Zhao, Yuchang Jiang, Zhaodi Wang, and Yong Jiang. Efficacy and safety evaluation of acupuncture therapy for patients with salpingitis in IVF-ET. A protocol of systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2020. http://dx.doi.org/10.37766/inplasy2020.11.0125.

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Yang, Liu, FX Liang, Y. Yuan, LY Wang, XF Luo, XH Zhang, and L. Yao. Efficacy of progestin-primed ovarian stimulation (PPOS) in patients with polycystic ovary syndrome during IVF/ICSI treatments: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2023. http://dx.doi.org/10.37766/inplasy2023.4.0059.

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Review question / Objective: This systematic review aims to evaluate the efficacy of progestin-primed ovarian stimulation (PPOS) on reproductive outcomes in patients with polycystic ovary syndrome (PCOS) undergoing assisted reproductive techniques. Condition being studied: PCOS is a common endocrine disorder that can cause infertility in women of childbearing age. The PPOS protocol, which involves oral progestins with gonadotropin (Gn), has been shown to be effective and safe in treating patients with PCOS. However, the question of whether PPOS provides a significant benefit over conventional GnRH analogue protocols in PCOS patients is still controversial.
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Yang, Huisheng. Comparative the clinical effectiveness and safety of controlled ovarian hyperstimulation for poor ovarian responders undergoing IVF/ICSI：a systematic review and bayesian network meta-analysis. INPLASY - International Platform of Registered Systematic Review Protocols, April 2020. http://dx.doi.org/10.37766/inplasy2020.4.0009.

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Zou, Zihao, Qianhuan Zheng, Xin Wen, Zuoqin Yang, Tinghui Hou, Xinyu Hao, Siyuan Zhou, and Ying Li. Pregnancy outcomes and the dose-related effects of acupuncture therapies in women undergoing in vitro fertilization (IVF): a protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0072.

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Gordon, Mark S. Theoretical Studies Of Group IVA And Group IVB Chemistry. Fort Belvoir, VA: Defense Technical Information Center, August 2014. http://dx.doi.org/10.21236/ada608927.

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Gordon, Mark S. Theoretical Studies of Group IVA and Group IVB Chemistry. Fort Belvoir, VA: Defense Technical Information Center, January 2012. http://dx.doi.org/10.21236/ada563643.

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