Relevant bibliographies by topics / Isocryptolepine

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  1. Journal articles

Academic literature on the topic 'Isocryptolepine'

Author: Grafiati
Published: 6 September 2023

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Journal articles on the topic "Isocryptolepine"

1

Wang, Ning, Marta Świtalska, Li Wang, et al. "Structural Modifications of Nature-Inspired Indoloquinolines: A Mini Review of Their Potential Antiproliferative Activity." Molecules 24, no. 11 (2019): 2121. http://dx.doi.org/10.3390/molecules24112121.

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Cryptolepine, neocryptolepine and isocryptolepine are naturally occurring indoloquinoline alkaloids with various spectrum of biological properties. Structural modification is an extremely effective means to improve their bioactivities. This review enumerates several neocryptolepine and isocryptolepine analogues with potent antiproliferative activity against MV4-11 (leukemia), A549 (lung cancer), HCT116 (colon cancer) cell lines in vitro. Its activity towards normal mouse fibroblasts BALB/3T3 was also evaluated. Furthermore, structure activity relationships (SAR) are briefly discussed. The anticancer screening of neocryptolepine derivatives was performed in order to determine their cytotoxic and growth inhibitory activities across the JFCR39 cancer cell line panel.
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2

Murray, Paul E., Keith Mills, and John A. Joule. "A Synthesis of Isocryptolepine." Journal of Chemical Research, no. 7 (1998): 377. http://dx.doi.org/10.1039/a801313f.

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3

Pousset, Jean-Louis, Marie-Therese Martin, Akino Jossang, and Bernard Bodo. "Isocryptolepine from Cryptolepis sanguinolenta." Phytochemistry 39, no. 3 (1995): 735–36. http://dx.doi.org/10.1016/0031-9422(94)00925-j.

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4

Aksenov, Alexander V., Dmitrii A. Aksenov, Georgii D. Griaznov, Nicolai A. Aksenov, Leonid G. Voskressensky, and Michael Rubin. "Unexpected cyclization of 2-(2-aminophenyl)indoles with nitroalkenes to furnish indolo[3,2-c]quinolines." Organic & Biomolecular Chemistry 16, no. 23 (2018): 4325–32. http://dx.doi.org/10.1039/c8ob00588e.

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5

Murray, Paul E., Keith Mills, and John A. Joule. "ChemInform Abstract: A Synthesis of Isocryptolepine." ChemInform 30, no. 15 (2010): no. http://dx.doi.org/10.1002/chin.199915254.

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6

Akitake, Masahiro, Shizuki Noda, Kohei Miyoshi, Motohiro Sonoda та Shinji Tanimori. "Access to γ-Carbolines: Synthesis of Isocryptolepine". Journal of Organic Chemistry 86, № 24 (2021): 17727–37. http://dx.doi.org/10.1021/acs.joc.1c02026.

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7

Kraus, George A., and Haitao Guo. "A direct synthesis of neocryptolepine and isocryptolepine." Tetrahedron Letters 51, no. 31 (2010): 4137–39. http://dx.doi.org/10.1016/j.tetlet.2010.05.141.

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8

Dubovitskii, S. V., O. S. Radchenko, and V. L. Norikov. "Synthesis of isocryptolepine, an alkaloid fromCryptolepis sanguinolenta." Russian Chemical Bulletin 45, no. 11 (1996): 2656–57. http://dx.doi.org/10.1007/bf01431136.

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9

Helgeland, Ida, and Magne Sydnes. "A Concise Synthesis of Isocryptolepine by C–C Cross-Coupling Followed by a Tandem C–H Activation and C–N Bond Formation." SynOpen 01, no. 01 (2017): 0041–44. http://dx.doi.org/10.1055/s-0036-1590807.

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Isocryptolepine (1), a potent antimalarial natural product, was prepared in three steps from 3-bromoquinoline and 2-aminophenylboronic acid hydrochloride. The key transformations were a Suzuki–Miyaura cross-coupling reaction followed by a palladium-initiated intramolecular C–H activation/C–N bond formation between an unprotected amine and an aromatic C–H group. The two key reactions can also be performed in one pot.
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10

Whittell, Louise R., Kevin T. Batty, Rina P. M. Wong, et al. "Synthesis and antimalarial evaluation of novel isocryptolepine derivatives." Bioorganic & Medicinal Chemistry 19, no. 24 (2011): 7519–25. http://dx.doi.org/10.1016/j.bmc.2011.10.037.

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