Journal articles: 'Irish OSB'

1

Farren, Sean. "The Blair Years – A Northern Irish Perspective1." Observatoire de la société britannique, no. 3 (February 1, 2007): 231–45. http://dx.doi.org/10.4000/osb.304.

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2

Considère-Charon, Marie-Claire. "Brexit and the Irish border issue : from May’s deal to Johnson’s deal." Observatoire de la société britannique, no. 25 (December 1, 2020): 149–66. http://dx.doi.org/10.4000/osb.4823.

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3

Cauvet, Philippe. "‘It’s not just the economy, stupid !’ Brexit, the Good Friday Agreement and the Irish border conundrum." Observatoire de la société britannique, no. 24 (September 1, 2019): 105–18. http://dx.doi.org/10.4000/osb.3276.

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4

Robson, Michael. "A. J. Fletcher & R. Gillespie (ed), Irish preaching, 700–1700; C. N. Ó Clabaigh OSB, The Franciscans in Ireland, 1400–1534: from reform to Reformation." Peritia 16 (January 2002): 499–504. http://dx.doi.org/10.1484/j.peri.3.513.

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5

Dabrowski, T., K. Lyons, C. Cusack, G. Casal, A. Berry, and G. D. Nolan. "Ocean modelling for aquaculture and fisheries in Irish waters." Ocean Science Discussions 12, no. 3 (June 25, 2015): 1187–217. http://dx.doi.org/10.5194/osd-12-1187-2015.

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Abstract. The Marine Institute, Ireland, runs a suite of operational regional and coastal ocean models. Recent developments include several tailored products that focus on the key needs of the Irish aquaculture sector. In this article, an overview of the products and services derived from the models are presented. A shellfish model that includes growth and physiological interactions of mussels with the ecosystem and is fully embedded in the 3-D numerical modelling framework has been developed at the Marine Institute. This shellfish model has a microbial module designed to predict levels of coliform contamination in mussels. This model can also be used to estimate the carrying capacity of embayments, assess impacts of pollution on aquaculture grounds and help to classify shellfish waters. The physical coastal model of southwest Ireland provides a three day forecast of shelf water movement in the region. This is assimilated into a new harmful algal bloom alert system used to inform end-users of potential toxic shellfish events and high biomass blooms that include fish killing species. Further services include the use of models to identify potential sites for offshore aquaculture, to inform studies of potential cross-contamination in farms from the dispersal of planktonic sea lice larvae and other pathogens that can infect finfish and to provide modelled products that underpin the assessment and advisory services on the sustainable exploitation of the marine fisheries resources. This paper demonstrates that ocean models can provide an invaluable contribution to the sustainable blue growth of aquaculture and fisheries.

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6

Crausaz, Janice, Marie Kelly, and Sarah Lee. "Three educational approaches to enhance the evidence-based practice behaviour of Irish occupational therapists." World Federation of Occupational Therapists Bulletin 64, no. 1 (November 2011): 11–17. http://dx.doi.org/10.1179/otb.2011.64.1.005.

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7

Webb, D. J. "On the shelf resonances of the English Channel and Irish Sea." Ocean Science Discussions 10, no. 1 (February 22, 2013): 393–433. http://dx.doi.org/10.5194/osd-10-393-2013.

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Abstract. The resonances of the English Channel and Irish Sea are investigated using the methods of Webb (2012) together with an Arakawa C-grid model of the region under study. In the semi-diurnal tidal band, the high tides of the Bristol Channel and Gulf of St. Malo are shown to be due to two shelf resonances which strongly couple the two regions. In the diurnal band, the response is complicated by the presence of continental shelf waves.

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8

Souza, A. J. "On the use of the Strouhal/Stokes number to explain the dynamics and water column structure on shelf seas." Ocean Science Discussions 9, no. 6 (December 10, 2012): 3723–38. http://dx.doi.org/10.5194/osd-9-3723-2012.

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Abstract. In recent years coastal oceanographers have suggested the use of the "Strouhal" number or it's inverse the "Stokes" number, which have been defined as the ratios of the frictional depth (δ) to the water column depth (h) or vice versa, to describe the effect of bottom boundary layer turbulence on the vertical structure of both density and currents. Although they have mention that the effects of rotation should be important, they have tended to omit it. This omission may be important when talking about tidal currents as the frictional depth from a fully cyclonic to a fully anticyclonic tidal ellipse can vary up to an order of magnitude in the mid latitudes; so that the stokes number might appear smaller (larger) than it is resulting in frictional effects being underestimated (overestimated). Here a way to calculate a Stokes number, in which the effect of the Earth's rotation is taken into account, is suggested. Then the standard Stokes and the rotational Stokes numbers are used as predictors for the position of the tidal mixing fronts in the Irish Sea. Results show that the rotational number improves prediction of the front in shallow cyclonic areas of the eastern Irish Sea. This suggest that the effect of rotation on the water column structure will be more important in shallow shelf seas and estuaries with strong rotational currents.

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9

O’Sullivan, Joan. "Advanced Dublin English as audience and referee design in Irish radio advertising." English World-Wide 39, no. 1 (February 1, 2018): 60–84. http://dx.doi.org/10.1075/eww.00003.osu.

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Abstract This paper examines change in the sociolinguistic landscape of Irish English based on a diachronic corpus of radio advertisements from 1997 and 2007, with a focus on the relatively new accent variety, Advanced Dublin English (AdvD) (Hickey 2013). The quantitative and qualitative analyses are based on Sussex’s (1989) “Action and Comment” framework (which differentiates the advertisement components based on discourse genre) and on Bell’s (1984) audience and referee design framework. AdvD is viewed in the 1997 subcorpus as outgroup referee design where it has an “initiative” role in constructing listener identity. In the 2007 subcorpus, the increased frequency of AdvD suggests that it is evolving to an audience designed style. Stylised representations of this accent can be understood as ingroup referee design, a strategy which facilitates the evolution of this form as audience design. These findings illustrate the initiative role of the media in constructing contemporary cultural identities (Piller 2001).

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10

O’Connell, A., E. M. Lawton, D. Leong, P. Cotter, D. Gleeson, and C. M. Guinane. "Detection of presumptive Bacillus cereus in the Irish dairy farm environment." Irish Journal of Agricultural and Food Research 55, no. 2 (December 1, 2016): 145–51. http://dx.doi.org/10.1515/ijafr-2016-0014.

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AbstractThe objective of the study was to isolate potentialBacillus cereussensu lato (B.cereus s.l.)from a range of farm environments. Samples of tap water, milking equipment rinse water, milk sediment filter, grass, soil and bulk tank milk were collected from 63 farms. In addition, milk liners were swabbed at the start and the end of milking, and swabs were taken from cows’ teats prior to milking. The samples were plated on mannitol egg yolk polymyxin agar (MYP) and presumptiveB. cereus s.l. colonies were isolated and stored in nutrient broth with 20% glycerol and frozen at -80 °C. These isolates were then plated on chromogenic medium (BACARA) and colonies identified as presumptiveB. cereus s.l. on this medium were subjected to 16S ribosomal RNA (rRNA) sequencing. Of the 507 isolates presumed to beB. cereus s.l. on the basis of growth on MYP, only 177 showed growth typical ofB. cereus s.l. on BACARA agar. The use of 16S rRNA sequencing to identify isolates that grew on BACARA confirmed that the majority of isolates belonged toB. cereus s.l. A total of 81 of the 98 isolates sequenced were tentatively identified as presumptiveB. cereus s.l. Pulsed-field gel electrophoresis was carried out on milk and soil isolates from seven farms that were identified as having presumptiveB. cereus s.l. No pulsotype was shared by isolates from soil and milk on the same farm. PresumptiveB. cereus s.l. was widely distributed within the dairy farm environment.

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11

McGrath, Tina. "Irish insights into the lived experience of breast cancer related lymphoedema: implications for occupation focused practice." World Federation of Occupational Therapists Bulletin 68, no. 1 (November 2013): 44–50. http://dx.doi.org/10.1179/otb.2013.68.1.012.

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12

Stansfield, K. L., M. R. Palmer, T. P. Rippeth, and J. H. Simpson. "Turbulent mixing in the seasonally-stratified western Irish Sea: a Thorpe Scale perspective." Ocean Science Discussions 10, no. 6 (November 19, 2013): 2141–55. http://dx.doi.org/10.5194/osd-10-2141-2013.

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Abstract. The seasonal thermocline in shelf-seas represents an important biogeophysical barrier to the vertical flux of nutrients into the photic zone. Episodic weakening of this barrier plays an important role in sustaining the sub-surface chlorophyll maximum in summer and hence impacts the carbon draw-down in the seasonally-stratified zones of the shelf seas. Here we present estimates of the rate of turbulent kinetic energy dissipation inferred from microstructure shear probes and compare them with dissipation rates inferred from a standard conductivity-temperature-depth instrument and from a fast thermistor (Thorpe Scale methodology) at a site in the seasonally-stratified Irish Sea. All methods show strong dissipation rates in response to tidal stresses near the bed (order 10−2 Wm−3) with qualitatively similar temporal and spatial patterns. In the interior of the water column, however, only the microstructure shear probe estimates resolve the mixing in the region of the thermocline.

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13

Dabrowski, T., K. Lyons, C. Cusack, G. Casal, A. Berry, and G. D. Nolan. "Ocean modelling for aquaculture and fisheries in Irish waters." Ocean Science 12, no. 1 (January 15, 2016): 101–16. http://dx.doi.org/10.5194/os-12-101-2016.

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Abstract. The Marine Institute, Ireland, runs a suite of operational regional and coastal ocean models. Recent developments include several tailored products that focus on the key needs of the Irish aquaculture sector. In this article, an overview of the products and services derived from the models are presented. The authors give an overview of a shellfish model developed in-house and that was designed to predict the growth, the physiological interactions with the ecosystem, and the level of coliform contamination of the blue mussel. As such, this model is applicable in studies on the carrying capacity of embayments, assessment of the impacts of pollution on aquaculture grounds, and the determination of shellfish water classes. Further services include the assimilation of the model-predicted shelf water movement into a new harmful algal bloom alert system used to inform end users of potential toxic shellfish events and high biomass blooms that include fish-killing species. Models are also used to identify potential sites for offshore aquaculture, to inform studies of potential cross-contamination in farms from the dispersal of planktonic sea lice larvae and other pathogens that can infect finfish, and to provide modelled products that underpin the assessment and advisory services on the sustainable exploitation of the resources of marine fisheries. This paper demonstrates that ocean models can provide an invaluable contribution to the sustainable blue growth of aquaculture and fisheries.

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14

Webb, D. J. "On the shelf resonances of the English Channel and Irish Sea." Ocean Science 9, no. 4 (August 26, 2013): 731–44. http://dx.doi.org/10.5194/os-9-731-2013.

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Abstract. The resonances of the English Channel and Irish Sea are investigated using the methods of Webb (2012a) together with an Arakawa C-grid model of the region under study. In the semi-diurnal tidal band, the high tides of the Bristol Channel and Gulf of St. Malo are shown to be due to two shelf resonances which strongly couple the two regions. In the diurnal band, the response is complicated by the presence of continental shelf waves.

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15

Babu, Gorla, and Pinjari Abdul Khayum. "Elephant herding with whale optimization enabled ORB features and CNN for Iris recognition." Multimedia Tools and Applications 81, no. 4 (December 29, 2021): 5761–94. http://dx.doi.org/10.1007/s11042-021-11746-7.

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16

Souza, A. J. "On the use of the Stokes number to explain frictional tidal dynamics and water column structure in shelf seas." Ocean Science 9, no. 2 (April 2, 2013): 391–98. http://dx.doi.org/10.5194/os-9-391-2013.

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Abstract. In recent years coastal oceanographers have suggested using the "Strouhal" number or its inverse, the "Stokes" number, to describe the effect of bottom boundary layer turbulence on the vertical structure of both density and currents. These are defined as the ratios of the frictional depth (δ) to the water column depth (h) or vice versa. Although many researchers have mentioned that the effects of the earth's rotation should be important, they have tended to omit it. Rotation may have an important influence on tidal currents, as the frictional depth from a fully cyclonic to a fully anticyclonic tidal ellipse can vary by up to an order of magnitude at mid latitudes. The Stokes number might appear smaller for cyclonic current ellipses (larger for anticyclonic) than it is without rotation, resulting in frictional effects being underestimated (overestimated). Here, a way to calculate a Stokes number is proposed, in which the effect of the earth's rotation is taken into account. The standard Stokes and the rotational Stokes numbers are used as predictors for the position of the tidal mixing fronts in the Irish Sea. Results show that use of the rotational number improves the predictions of fronts in shallow cyclonic areas of the eastern Irish Sea. This suggests that the effect of rotation on the water column structure will be more important in shallow shelf seas and estuaries with strong rotational currents.

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17

SMEDLEY, P. L. "Trace Element and Isotopic Variations in Scottish and Irish Dinantian Volcanism: Evidence for an OIB-like Mantle Source." Journal of Petrology 29, no. 2 (April 1, 1988): 413–43. http://dx.doi.org/10.1093/petrology/29.2.413.

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18

Costa, Valter, Armando Sousa, and Ana Reis. "Cork as a Unique Object: Device, Method, and Evaluation." Applied Sciences 8, no. 11 (November 3, 2018): 2150. http://dx.doi.org/10.3390/app8112150.

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Unique Objects (UNOs) are relevant for real-world applications such as anti-counterfeiting systems. In this work, cork is demonstrated as a UNO, part of the Physical Unclonability and Disorder (PUD) system. An adequate measurement kit (illumination device) and recognition method are also devised and evaluated. Natural hills and valleys of the cork are enhanced using the illumination device and the overall robustness of the recognition application inherent to UNOs is presented. The lighting device is based on grazing light and the recognition task is based on a local feature detector and descriptor called ORB - Oriented FAST (Features from Accelerated Segment Test) and Rotated BRIEF (Binary Robust Independent Elementary Features). The performance evaluation utilizes a private cork database (1500 photos of 500 cork stoppers) and three public iris databases. In the tests carried out on the illumination device, the results clearly show the success of capturing stable/repeatable features needed for the recognition task in the cork database. This achievement is also reflected in the perfect recognition score achieved in the cork database, in the intra-distance measure μ i n t r a , which gives the notion of average noise between measures, and in the inter-distance μ i n t e r which provides hints about the randomness/uniqueness of a cork. Regarding the recognition application, its effectiveness is further tested using the iris databases. Regardless of the fact that the recognition algorithm was not designed for the iris recognition problem, the results show that the proposed approach is capable of competing with the techniques found in the literature specially designed for iris recognition. Furthermore, the evaluation shows that the three requirements that constitute a UNO (Disorder, Operability, and Unclonability) are fulfilled, thus supporting the main assertion of this work: that cork is a UNO.

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19

O'Neill, C. K., J. A. Polton, J. T. Holt, and E. J. O'Dea. "Modelling temperature and salinity in Liverpool Bay and the Irish Sea: sensitivity to model type and surface forcing." Ocean Science Discussions 9, no. 2 (February 17, 2012): 649–85. http://dx.doi.org/10.5194/osd-9-649-2012.

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Abstract. Three shelf sea models are compared against observed surface temperature and salinity in Liverpool Bay and the Irish Sea: a 7 km NEMO model, and 12 km and 1.8 km POLCOMS models. Each model is run with two different surface forcing datasets of different resolutions. Comparisons with a variety of observations from the Liverpool Bay Coastal Observatory show that increasing the surface forcing resolution improves the modelled surface temperature in all the models, in particular reducing the summer warm bias and winter cool bias. The response of surface salinity is more varied with improvements in some areas and deterioration in others. The 7 km NEMO model performs as well as the 1.8 km POLCOMS model when measured by overall skill scores although the sources of error in the models are different. NEMO is too weakly stratified in Liverpool Bay, whereas POLCOMS is too strongly stratified. The horizontal salinity gradient, which is too strong in POLCOMS, is better reproduced by NEMO which uses a more diffusive horizontal advection scheme. This leads to improved semi-diurnal variability in salinity in NEMO at a mooring site located in the Liverpool Bay ROFI area.

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20

Garaba, S. P., M. R. Wernand, and O. Zielinski. "Quality control of automated hyperspectral remote sensing measurements from a seaborne platform." Ocean Science Discussions 8, no. 2 (March 30, 2011): 613–38. http://dx.doi.org/10.5194/osd-8-613-2011.

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Abstract. In this study four data quality flags are presented for automated and unmanned above-water hyperspectral optical measurements collected underway in the North Sea, The Minch, Irish Sea and Celtic Sea in April/May 2009. Coincident to these optical measurements a DualDome D12 (Mobotix, Germany) camera system was used to capture sea surface and sky images. The first three flags are based on meteorological conditions, to select erroneous incoming solar irradiance (ES) taken during dusk, dawn, before significant incoming solar radiation could be detected or under rainfall. Furthermore, the relative azimuthal angle of the optical sensors to the sun is used to identify possible sunglint free sea surface zones. A total of 629 spectra remained after applying the meteorological masks (first three flags). Based on this dataset, a fourth flag for sunglint was generated by analysing and evaluating water leaving radiance (LW) and remote sensing reflectance (RRS) spectral behaviour in the presence and absence of sunglint salient in the simultaneously available sea surface images. Spectra conditions satisfying "mean LW (700–950 nm) < 2 mW m−2 nm−1 Sr−1" or alternatively "minimum RRS (700–950 nm) < 0.010 Sr−1", mask the most measurements affected by sunglint, providing efficient flagging of sunglint in automated quality control. It is confirmed that valid optical measurements can be performed 0° ≤ Φ ≤ 360° although 90° ≤ Φ ≤ 135° is recommended.

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21

O'Neill, C. K., J. A. Polton, J. T. Holt, and E. J. O'Dea. "Modelling temperature and salinity in Liverpool Bay and the Irish Sea: sensitivity to model type and surface forcing." Ocean Science 8, no. 5 (October 29, 2012): 903–13. http://dx.doi.org/10.5194/os-8-903-2012.

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Abstract. Three shelf sea models are compared against observed surface temperature and salinity in Liverpool Bay and the Irish Sea: a 7 km NEMO (Nucleus for European Modelling of the Ocean) model, and 12 km and 1.8 km POLCOMS (Proudman Oceanographic Laboratory Coastal Ocean Modelling System) models. Each model is run with two different surface forcing datasets of different resolutions. Comparisons with a variety of observations from the Liverpool Bay Coastal Observatory show that increasing the surface forcing resolution improves the modelled surface temperature in all the models, in particular reducing the summer warm bias and winter cool bias. The response of surface salinity is more varied with improvements in some areas and deterioration in others. The 7 km NEMO model performs as well as the 1.8 km POLCOMS model when measured by overall skill scores, although the sources of error in the models are different. NEMO is too weakly stratified in Liverpool Bay, whereas POLCOMS is too strongly stratified. The horizontal salinity gradient, which is too strong in POLCOMS, is better reproduced by NEMO which uses a more diffusive horizontal advection scheme. This leads to improved semi-diurnal variability in salinity in NEMO at a mooring site located in the Liverpool Bay ROFI (region of freshwater influence) area.

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22

Signell, R. P., and E. Camossi. "Technical note: Harmonizing met-ocean model data via standard web services within small research groups." Ocean Science Discussions 12, no. 6 (November 5, 2015): 2655–82. http://dx.doi.org/10.5194/osd-12-2655-2015.

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Abstract. Work over the last decade has resulted in standardized web-services and tools that can significantly improve the efficiency and effectiveness of working with meteorological and ocean model data. While many operational modelling centres have enabled query and access to data via common web services, most small research groups have not. The penetration of this approach into the research community, where IT resources are limited, can be dramatically improved by: (1) making it simple for providers to enable web service access to existing output files; (2) using technology that is free, and that is easy to deploy and configure; and (3) providing tools to communicate with web services that work in existing research environments. We present a simple, local brokering approach that lets modelers continue producing custom data, but virtually aggregates and standardizes the data using NetCDF Markup Language. The THREDDS Data Server is used for data delivery, pycsw for data search, NCTOOLBOX (Matlab®1) and Iris (Python) for data access, and Ocean Geospatial Consortium Web Map Service for data preview. We illustrate the effectiveness of this approach with two use cases involving small research modelling groups at NATO and USGS.1 Mention of trade names or commercial products does not constitute endorsement or recommendation for use by the US Government.

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23

Cooper, Matthew, Charles Bishop, Matthew Lewis, David Bowers, Mark Bolton, Ellie Owen, and Stephen Dodd. "What can seabirds tell us about the tide?" Ocean Science 14, no. 6 (November 29, 2018): 1483–90. http://dx.doi.org/10.5194/os-14-1483-2018.

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Abstract. Small global positioning system (GPS) trackers are now routinely used to study the movement and behaviour of birds at sea. If the birds rest on the water they become “drifters of opportunity” and can be used to give information about surface currents. In this paper, we use a small data set from satellite-tracked razorbills (Alca torda) in the Irish Sea to test the potential of this idea for measuring tidal currents. Razorbills regularly rest on the sea overnight and their tracks at this time are consistent with their drifting with the tidal flows and changing direction as the flood turns to ebb and vice versa. Data from 4 years (2011–2014) have been binned in a geographical grid and analysed to give the variation of current over a mean tidal cycle in each grid element. A map of maximum current speed is consistent with a numerical model of the tidal currents in the region. The root mean square difference between observed maximum speed and that predicted by the model is 0.15 m s−1, about 15 % of typical current speeds in the area. The divergence between bird-track speed and model prediction increases in regions of the fastest tidal currents. The method clearly has its limitations, but the results of this study show that tagged birds resting on the sea have potential to provide relatively inexpensive quantitative information about surface tidal currents over an extended geographical area.

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24

Maraldi, C., J. Chanut, B. Levier, N. Ayoub, P. De Mey, G. Reffray, F. Lyard, et al. "NEMO on the shelf: assessment of the Iberia–Biscay–Ireland configuration." Ocean Science 9, no. 4 (August 26, 2013): 745–71. http://dx.doi.org/10.5194/os-9-745-2013.

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Abstract. This work describes the design and validation of a high-resolution (1/36°) ocean forecasting model over the "Iberian–Biscay–Irish" (IBI) area. The system has been set-up using the NEMO model (Nucleus for European Modelling of the Ocean). New developments have been incorporated in NEMO to make it suitable to open- as well as coastal-ocean modelling. In this paper, we pursue three main objectives: (1) to give an overview of the model configuration used for the simulations; (2) to give a broad-brush account of one particular aspect of this work, namely consistency verification; this type of validation is conducted upstream of the implementation of the system before it is used for production and routinely validated; it is meant to guide model development in identifying gross deficiencies in the modelling of several key physical processes; and (3) to show that such a regional modelling system has potential as a complement to patchy observations (an integrated approach) to give information on non-observed physical quantities and to provide links between observations by identifying broader-scale patterns and processes. We concentrate on the year 2008. We first provide domain-wide consistency verification results in terms of barotropic tides, transports, sea surface temperature and stratification. We then focus on two dynamical subregions: the Celtic shelves and the Bay of Biscay slope and deep regions. The model–data consistency is checked for variables and processes such as tidal currents, tidal fronts, internal tides and residual elevation. We also examine the representation in the model of a seasonal pattern of the Bay of Biscay circulation: the warm extension of the Iberian Poleward Current along the northern Spanish coast (Navidad event) in the winter of 2007–2008.

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Signell, Richard P., and Elena Camossi. "Technical note: Harmonising metocean model data via standard web services within small research groups." Ocean Science 12, no. 3 (May 4, 2016): 633–45. http://dx.doi.org/10.5194/os-12-633-2016.

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Abstract. Work over the last decade has resulted in standardised web services and tools that can significantly improve the efficiency and effectiveness of working with meteorological and ocean model data. While many operational modelling centres have enabled query and access to data via common web services, most small research groups have not. The penetration of this approach into the research community, where IT resources are limited, can be dramatically improved by (1) making it simple for providers to enable web service access to existing output files; (2) using free technologies that are easy to deploy and configure; and (3) providing standardised, service-based tools that work in existing research environments. We present a simple, local brokering approach that lets modellers continue to use their existing files and tools, while serving virtual data sets that can be used with standardised tools. The goal of this paper is to convince modellers that a standardised framework is not only useful but can be implemented with modest effort using free software components. We use NetCDF Markup language for data aggregation and standardisation, the THREDDS Data Server for data delivery, pycsw for data search, NCTOOLBOX (MATLAB®) and Iris (Python) for data access, and Open Geospatial Consortium Web Map Service for data preview. We illustrate the effectiveness of this approach with two use cases involving small research modelling groups at NATO and USGS.

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Momen, Mehdi, Nyah L. Kohler, Emily E. Binversie, Mariellen Dentino, and Susannah J. Sample. "Heritability and genetic variance estimation of Osteosarcoma (OSA) in Irish Wolfhound, using deep pedigree information." Canine Medicine and Genetics 8, no. 1 (October 9, 2021). http://dx.doi.org/10.1186/s40575-021-00109-y.

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Abstract Background Osteosarcoma (OSA) is a devastating disease that is common in the Irish Wolfhound breed. The aim of this study was to use a pedigree-based approach to determine the heritability of OSA in the Irish Wolfhound using data from a large publically available database. Results The pedigree used for this study included 5110 pure-bred Irish Wolfhounds, including 332 dogs diagnosed with OSA and 360 control dogs; dogs were considered controls if they lived over 10 years of age and were not reported to have developed OSA. The estimated heritability of OSA in the Irish Wolfhound was 0.65. Conclusion The results of this study indicate that OSA in the Irish Wolfhound is highly heritable, and support the need for future research investigating associated genetic mutations.

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Крючкова, Т. А., and Е. В. Матвиенко. "Norry's disease in a child: clinical case." Лечащий врач, no. 7-8(25) (September 3, 2022). http://dx.doi.org/10.51793/os.2022.25.8.013.

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В последнее время отмечается тенденция к увеличению частоты наследственных заболеваний у детей во всем мире. Болезнь Норри – редкое генетическое заболевание, которое характеризуется аномалией развития сетчатки глаз и врожденной слепотой. В статье представлен клинический случай болезни Норри у ребенка 4 лет и 2 месяцев. Из анамнеза жизни известно, что пациент от первой патологически протекавшей беременности и родов. В течение беременности у матери ребенка отмечались гестоз, угроза прерывания беременности, высокий титр антител к Chlamydia trachomatis. В возрасте одного месяца офтальмологом впервые выставлен диагноз: «Болезнь Норри». Неоднократно обследован в НИИ глазных болезней им. Гельмгольца (г. Москва). Хирургическое лечение отслойки сетчатки признано бесперспективным. Впервые диагноз болезни Норри был подтвержден молекулярно-генетическим методом в 9-месячном возрасте пациента. В возрасте 11 месяцев ребенок был госпитализирован в ДКБ Санкт-Петербурга, где произведен I этап операции на левом глазу – ленсвитршвартэктомия, дренаж субретинальной жидкости, пластика радужной оболочки. Спустя 2 месяца проведено оперативное лечение на правом глазу – ленсвитршвартэктомия, дренаж субретинальной жидкости, пластика радужной оболочки. Послеоперационный период протекал без осложнений, однако прогноз специалистов в отношении зрения бесперспективен. Через год ребенку были проведены повторные этапные органосохраняющие операции на правом глазу. Отмечалась положительная динамика, заключающаяся в уменьшении степени патологического смещения кпереди экваториальных отделов ретинальной ткани. В статье отмечены основные этапы диагностики болезни Норри у пациента, представлены особенности клинического течения заболевания и наблюдения за больным ребенком в динамике. Заболевание органов зрения, вероятно, было сформировано в результате комплексной антенатальной патологии еще в течение первой половины беременности у матери ребенка. Recently, there has been a tendency to increase the incidence of hereditary diseases in children around the world. Norrie's disease is a rare genetic disease that is characterized by an abnormality in the development of the retina and congenital blindness. The article presents a clinical case of Norrie's disease in a child aged 4 years and 2 months. From the anamnesis of life it is known that the patient is from 1 pathologically proceeding pregnancy and childbirth. During pregnancy, the mother of the child had gestosis, a threat of abortion, a high titer of antibodies to Chlamydia trachomatis. At the age of 1 month, an ophthalmologist was first diagnosed with: Norrie's disease? Repeatedly examined at the Research Institute of Eye Diseases named Helmholtz (Moscow). Surgical treatment of retinal detachment is considered futile. For the first time, the diagnosis of Norrie's disease was confirmed by the molecular genetic method at the age of the patient 9 months. At the age of 11 months, the child was hospitalized in the Children's Clinical Hospital (St. Petersburg), where he underwent 1 stage of surgery on his left eye – lensvitrshvartectomy, subretinal fluid drainage, and iris plastic surgery. After 2 months, surgical treatment was performed on the right eye – lensvitrshvartectomy, drainage of the subretinal fluid, plastic iris. The postoperative period was uneventful, but the prognosis of specialists regarding vision is unpromising. After a year, the child underwent repeated organ-sparing surgeries in the right eye. Positive dynamics was noted, consisting in a decrease in the degree of pathological displacement anteriorly of the equatorial sections of the retinal tissue. The article notes the main stages of the diagnosis of Norrie's disease in a patient, presents the features of the clinical course of the disease and monitoring the sick child in dynamics. The disease of the organs of vision was probably formed as a result of complex antenatal pathology during the first half of pregnancy in the mother of the child.

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Journal articles on the topic 'Irish OSB'

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