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Journal articles on the topic 'IPCM'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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1

Toblli, Jorge, Gabriel Cao, Margarita Angerosa, and Roberto Cacchione. "Early Toxicity In the Gastrointestinal Tract Is Greater with An Iron(III) Polymaltose Complex (IPC) Similar Vs the Originator IPC Preparation: Results From A Rat Model." Blood 118, no. 21 (November 18, 2011): 1040. http://dx.doi.org/10.1182/blood.v118.21.1040.1040.

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Abstract Abstract 1040 Background: Iron(III) polymaltose complex (IPC) shows similar efficacy to ferrous sulfate for the treatment of iron deficiency anemia but with superior tolerability. The stable structure of IPC prevents unregulated uptake of iron from the gut, avoiding an increase in non-transferrin bound iron with associated oxidative stress. IPC similars have been developed which vary in structure from the originator IPC preparation (Maltofer®, IPCM). A direct comparison between the originator and IPC similars in their potential to induce oxidative stress has not been performed. In this study, we compared acute and early toxicity in the gastrointestinal (GI) tract and liver in healthy rats randomized to IPCM, an IPC similar (Vitalix, IPCV) or a control arm. Methods: LD50 values were determined by administering single increasing doses of IPCM or IPCV (each n=12) and counting deaths at 24 hours. Three groups of rats (each n=12) then received doses equivalent to 10% of LD50 for IPCM (280 mg iron/kg/day) or IPCV (280 mg iron/kg/day), or tap water (controls) for 28 days. Iron-induced lesions in the GI tract were scored: 1, superficial 1–5 hemorrhagic points; 2, superficial 6–10, hemorrhagic points; 3, sub-mucosal hemorrhagic lesions with small erosions; 4, severe hemorrhagic lesions and some invasive lesions. Iron deposits (Prussian blue) and tissue ferritin in the liver and small intestine were assessed by immunohistochemistry. Ferritin immunostaining in the small intestine was scored: 1, none; 2, mild; 3, moderate; 4, very intense. Results: LD50 was the same for IPCM and IPCV (>2800 mg iron/kg). Animals treated with IPCV had lower food consumption and body weight vs those treated with IPCM and controls. IPCV was associated with increased serum iron and transferrin saturation vs the IPCM group, suggesting bypass of the regulated iron uptake system. Microscopically, the villi/crypt ratio and the number of Goblet cells per villi in the small intestine were significantly lower with IPCV vs IPCM or controls, and the number of eosinophils per villi was increased in IPCV-treated animals. Gross anatomy and microscopy findings showed that IPCV- treated animals experienced variable degrees of inflammation in the GI tract while the IPCM and control groups showed no lesions. Ferritin immunostaining of liver tissue indicated that iron was appropriately stored in IPCM-treated within Kupffer's cells (Prussian blue). Ferritin deposits in the small intestine were also higher with IPCM. Differences were statistically inferior for IPCV versus IPCM for clinical and iron parameters, gross anatomy, microscopic findings and ferritin immunostaining (Table). Conclusions: IPCV showed the same LD50 as IPCM, but considerably greater early GI tract toxicity. Increased numbers of eosinophils in the IPCV group suggest an allergic component of the small intestine injury in these groups. Markers of iron transport and distribution indicated less well controlled uptake and storage following ingestion of IPCV compared to IPCM. The increased levels of ferritin deposits in the small intestine of IPCM-treated animals suggests that excess iron is stored in the gut wall instead of saturating the iron transport mechanism and increasing non-transferrin bound iron levels. Disclosures: Toblli: Vifor (International) Ltd: Consultancy, Research Funding.
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Kang, Shinyoung, Juyoung Lee, Myounggon Kang, and Yunheub Song. "Achievement of Gradual Conductance Characteristics Based on Interfacial Phase-Change Memory for Artificial Synapse Applications." Electronics 9, no. 8 (August 7, 2020): 1268. http://dx.doi.org/10.3390/electronics9081268.

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In this paper, gradual and symmetrical long-term potentiation (LTP) and long-term depression (LTD) were achieved by applying the optimal electrical pulse condition of the interfacial phase-change memory (iPCM) based on a superlattice (SL) structure fabricated by stacking GeTe/Sb2Te3 alternately to implement an artificial synapse in neuromorphic computing. Furthermore, conventional phase-change random access memory (PCRAM) based on a Ge–Sb–Te (GST) alloy with an identical bottom electrode contact size was fabricated to compare the electrical characteristics. The results showed a reduction in the reset energy consumption of the GeTe/Sb2Te3 (GT/ST) iPCM by more than 69% of the GST alloy for each bottom electrode contact size. Additionally, the GT/ST iPCM achieved gradual conductance tuning and 90.6% symmetry between LTP and LTD with a relatively unsophisticated pulse scheme. Based on the above results, GT/ST iPCM is anticipated to be exploitable as a synaptic device used for brain-inspired computing and to be utilized for next-generation non-volatile memory.
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Guthrie, J. Peter, and Igor Povar. "A test of various computational solvation models on a set of “difficult” organic compounds." Canadian Journal of Chemistry 87, no. 8 (August 2009): 1154–62. http://dx.doi.org/10.1139/v09-071.

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Various dielectric continuum models in Gaussian 03, based on the SCRF approach, PCM, CPCM, DPCM, IEFPCM, IPCM, and SCIPCM, have been tested on a set of 54 highly polar, generally polyfunctional compounds for which experimental solvation energies are available. These compounds span a range of 13 kcal/mol in ΔGt. The root-mean-square (RMS) errors for the full set of compounds range from 2.48 for DPCM to 1.77 for IPCM. For each method, classes of compounds which were not handled well could be identified. If these classes of compounds were omitted, the performance improved, and ranged from 1.58 (PCM, 39 compounds) to 1.02 (IPCM, 42 compounds). Models in the PCM family (PCM, CPCM, DPCM, and IEFPCM) with the recommended UAHF or UAKS sets of radii rely on a highly parameterized definition of the solvent cavity. Where this parameterization was inadequate, the calculated solvation energies were less reliable. This has been demonstrated by devising a new parameterization for PCM and halogen compounds, which markedly improves performance for polyhalogen compounds. The effective radius for the portion of the cavity centered on a halogen atom was assumed to be linear in the electron-withdrawing or -donating properties of the rest of the molecule as measured by Hammett σ (for halogens on aromatic rings) or Taft σ* (for halogens on aliphatic carbons). This new parameterization for PCM was tested on a set of 45 aliphatic and 22 aromatic polyhalogen compounds and shown to do well. IPCM, which was already the best of the methods in Gaussian, can be considerably improved by a parameterization to allow for cavitation, dispersion, and hydrogen bonding. A large set of compounds was used for the parameterization to have multiple examples for each parameter and as far as possible to have molecules with multiple instances of each structural feature. In the end, 15 parameters were found to be defined by the data for 241 compounds. With this parameter set, the RMS error for the set used for fitting was 0.81 kcal/mol, and the RMS error for the original set of 54 compounds was 0.85. With this new parameterization, IPCM is clearly the best of the methods available in Gaussian 03.
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4

Wu, Xiao Hong, Bin Wu, and Jie Wen Zhao. "Improved Inter-Cluster Separation Algorithm." Key Engineering Materials 439-440 (June 2010): 361–66. http://dx.doi.org/10.4028/www.scientific.net/kem.439-440.361.

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The inter-cluster separation (ICS) algorithm adds the separation item into the objective function to minimize the fuzzy Euclidean distance and maximize the inter-cluster separation. However, ICS is sensitive to noisy data, so an improved inter-cluster separation (IICS) algorithm is proposed to deal with this problem. It is claimed that IICS is an incorporation of ICS and improved possibilistic c-means (IPCM) clustering. IICS can produce both possibilities and memberships simultaneously, and it overcomes the noise sensitivity problem of ICS and the coincident clusters problem of possibilistic c-means (PCM) clustering. Further, IICS does not depend on the parameters that exist in IPCM. The experimental results show that IICS compares favorably with ICS.
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5

Kolobov, A. V., P. Fons, Y. Saito, and J. Tominaga. "Reconfiguration of van der Waals Gaps as the Key to Switching in GeTe/Sb2Te3 Superlattices." MRS Advances 3, no. 57-58 (2018): 3413–18. http://dx.doi.org/10.1557/adv.2018.444.

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AbstractGeTe/Sb2Te3 superlattices, also known as interfacial phase-change memory (iPCM), exhibit significantly faster switching and are characterized by much lower power consumption and longer data retention compared to devices based on alloyed materials. In early work, the superior performance of iPCM was linked to a crystal-crystal transition between the SET and RESET states. As the primary mechanism, a change in the stacking order of Ge and Te planes within a GeTe block was suggested. Subsequent STEM studies on epitaxial GeTe/Sb2Te3 superlattices demonstrated that the GeTe blocks were not located between Sb2Te3 quintuple layers but, were incorporated inside the latter, providing a serious challenge to the early explanation. In this work, we demonstrate that changes associated with the reconstruction of the SbTe terminating layers nearest to van der Waals gap leads to a pronounced change in the density of states and can serve as an alternative explanation for a large property contrast between the SET and RESET states in GeTe/Sb2Te3 superlattices.
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6

Carvalho, Marco Aurelio, Nelson Paiva Oliveira Leite, and Roberto d'Amore. "iPCM Telemetry Protocol: Reliability and Bandwidth Improvement for PCM IRIG-106." IEEE Transactions on Aerospace and Electronic Systems 56, no. 1 (February 2020): 155–66. http://dx.doi.org/10.1109/taes.2019.2913599.

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7

WENZEL, JANE M., and ELMER H. MARTH. "Behavior of Listeria monocytogenes in the Presence of Streptococcus lactis in a Medium with Internal pH Control." Journal of Food Protection 53, no. 11 (November 1, 1990): 918–23. http://dx.doi.org/10.4315/0362-028x-53.11.918.

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Growth of Listeria monocytogenes strains V7, Scott A, and California (initial inoculum 103/ml) at 21 or 30°C in the presence of Streptococcus Iactis (initial inoculum 0.25 or 1.0%) was determined using a medium with internal pH control (IPCM-1). The pH of the uninoculated medium (control) was 7.0 before and after incubation. Populations of L. monocytogenes in IPCM-1 without S. lactis after 30 h at 21°C were ca. 107/ml for strains V7 and Scott A and ca. 106/ml for strain California, and at 30°C they were ca. 108/ml for all three strains. When data were plotted, areas of graphs between curves representing controls and treatments were calculated to quantitate the extent of inhibition of L. monocytogenes caused by S. lactis. Each such area is called the “area of inhibition” (AI). Growth of the pathogen was inhibited by S. lactis; the degree was dependent on temperature and concentration of lactic culture and, in some instances, strain of Listeria. Greatest inhibition of each strain occurred with the largest inoculum of S. lactis and at the highest temperature. No significant difference (p>0.05) in AI or pH among the three strains was observed at 21°C. At 30°C, strain California was inhibited significantly more (p<0.05) than V7 or Scott A by both concentrations of S. lactis at 24 and 30 h of incubation. No significant difference (p>0.05) in pH was found at this temperature regardless of concentration of S. lactis or strain of Listeria. IPCM-1 inoculated with a lactic starter culture is ready for use at pH 5.5 after 15–18 h of incubation. Inhibition of Listeria was not complete at this pH under any of the experimental conditions. Substantial numbers of L. monocytogenes (103–105 CFU/ml) were present when this medium was ready for use to produce cultured dairy foods.
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WENZEL, JANE M., and ELMER H. MARTH. "Behavior of Listeria monocytogenes in the Presence of Lactic Acid Bacteria in an Agitated Medium with Internal pH Control." Journal of Food Protection 54, no. 3 (March 1, 1991): 183–88. http://dx.doi.org/10.4315/0362-028x-54.3.183.

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An agitated medium with internal pH control (IPCM-2) was inoculated to contain Listeria monocytogenes (strain V7, Scott A or California) at ca. 103 CFU/ml and Streptococcus cremoris (Lactococcus lactis subsp. cremoris) or Streptococcus lactis (Lactococcus lactis subsp. lactis) at 0.25 or 1.0% The inoculated medium was incubated with shaking in a waterbath at 30°C for 30 h. L. monocytogenes and lactic acid bacteria were enumerated and pH was determined at appropriate intervals. The area on a figure between curves for the control and treatment and designated as the area of inhibition (AI) was calculated and used to quantify inhibition of each strain of L. monocytogenes for a particular set of conditions in IPCM-2. Statistical analysis of AI values calculated from data obtained at 6, 24, and 30 h of incubation revealed no significant (p < 0.05) difference in inhibition among the three strains of L. monocytogenes for each type of lactic streptococcus present. Streptococcus cremoris was significantly (0.01 < p < 0.05) more inhibitory to all three strains of L. monocytogenes than was S. lactis at 24 and 30 h of incubation. IPCM-2 is considered ready for use at a pH of 5.4 or less, which was reached between 12 and 15 h of incubation in samples containing 0.25 or 1.0% S. cremoris. Populations of L. monocytogenes in such samples were ca. 104 to 106 CFU/ml regardless of strain of Listeria or percentage of S. cremoris added as inoculum. In samples initially containing 0.25 or 1.0% S. lactis, pH 5.4 was not reached until after 18–24 h of incubation. At this point all three strains of L. monocytogenes had grown to ca. 105 CFU/ml regardless of percentage of S. lactis added as inoculum. Despite the inhibition seen, substantial numbers of the pathogen were present when the medium was ready for use.
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9

Mohammad Athar Ali, and Eran A. Edirisinghe. "Reversible Watermarking using Differential Expansion on IPCM Macroblocks in H.264/AVC." Journal of Next Generation Information Technology 2, no. 1 (February 28, 2011): 105–16. http://dx.doi.org/10.4156/jnit.vol2.issue1.12.

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10

Lee, Ho-Jin, Hee Jung Jung, Jong Hyun Kim, Hyun-Mee Park, and Kang-Bong Lee. "Conformational preference of azaglycine-containing dipeptides studied by PCM and IPCM methods." Chemical Physics 294, no. 2 (October 2003): 201–10. http://dx.doi.org/10.1016/j.chemphys.2003.06.001.

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11

Mitrofanov, K. V., Y. Saito, N. Miyata, P. Fons, A. V. Kolobov, and J. Tominaga. "Effects of electric and magnetic fields on the resistive switching operation of iPCM." Applied Physics Letters 116, no. 20 (May 18, 2020): 201903. http://dx.doi.org/10.1063/1.5135608.

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12

WANG, XING-JIAN, QUAN ZHU, and XIANG-YUAN LI. "HYDRATION FREE ENERGY AND ABSORPTION SPECTRUM OF AN EXTRA ELECTRON IN WATER BY QUANTUM-CONTINUUM MODEL." Journal of Theoretical and Computational Chemistry 07, no. 04 (August 2008): 767–75. http://dx.doi.org/10.1142/s0219633608004118.

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In this paper, the hydration energy of electron and absorption spectrum at room temperature have been estimated by quantum-continuum model. Taking a number of negatively charged water clusters as the quantum part, the hydration energy is calculated at high levels associated with IPCM and IEFPCM. The optical absorption spectrum is calculated by TDDFT with different basis sets. The vertical detachment energy and cluster reorganization energy in gas phase are also investigated. The results have been discussed by comparing with the experimental observations.
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13

Kash, Bita A., Paul Ogden, Elizabeth Popp, Melissa Shaffer, and Jane Bolin. "Exploring future models of primary care for Texas." International Journal of Innovation Science 9, no. 4 (December 4, 2017): 435–54. http://dx.doi.org/10.1108/ijis-01-2017-0005.

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Purpose The purpose of this study is to identify best practices for innovative primary care models and to describe a potential future primary care (PC) model for Texas to address the burden of chronic disease in a population-based approach. Design/methodology/approach A systematic literature review was conducted and identified 1,880 published records through PubMed using 26 search terms. After abstract and full-text review, 70 articles remained as potential models. Findings Although there is already a severe shortage of physicians in Texas, emerging practice patterns and choices among physicians are likely to erode access to primary care services in the state. Health-care leaders are encouraged to consider models such as complex adaptive systems for team-based care, pharmacist hypertension care management program and combined nurse-led care management with group visit structure. Research limitations/implications As with any study, this research has its limitations; for example, models that might work in one state, or under a unique state-funded academic medical center, might not be “do-able” in another state within the nuances of a different funding mechanism. Practical implications Results of this research provide a model for implementing IPCM for the state of Texas first and will guide IPCM planning and implementation in other states. Originality/value This study is “land grant-centric” and focused on carrying out the mission of a major, top-tier research university with an emerging college of medicine at an academic medical center.
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Kapotas, Spyridon K., and Athanassios N. Skodras. "Real time data hiding by exploiting the IPCM macroblocks in H.264/AVC streams." Journal of Real-Time Image Processing 4, no. 1 (October 11, 2008): 33–41. http://dx.doi.org/10.1007/s11554-008-0100-2.

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15

Rodríguez, Ana M., Joseph C. P. Koo, Dante E. Rojas, Nélida M. Peruchena, and Ricardo D. Enriz. "Conformational and electronic study ofN-acetyl-L-isoleucine-N-methylamide using DFT and IPCM calculations." International Journal of Quantum Chemistry 106, no. 7 (2006): 1580–95. http://dx.doi.org/10.1002/qua.20883.

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16

Mitrofanov, Kirill V., Yuta Saito, Noriyuki Miyata, Paul Fons, Alexander V. Kolobov, and Junji Tominaga. "High‐Speed Bipolar Switching of Sputtered Ge–Te/Sb–Te Superlattice iPCM with Enhanced Cyclability." physica status solidi (RRL) – Rapid Research Letters 13, no. 8 (April 26, 2019): 1900105. http://dx.doi.org/10.1002/pssr.201900105.

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Wu, Xiao Hong, Tong Xiang Cai, Bin Wu, and Jun Sun. "Research on the Variety Discrimination of Apple Using a Hybrid Possibilistic Clustering." Advanced Materials Research 710 (June 2013): 768–71. http://dx.doi.org/10.4028/www.scientific.net/amr.710.768.

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Near infrared reflectance (NIR) spectroscopy has been used to obtain NIR spectra of two varieties of apple samples. The dimensionality of NIR spectra was reduced by principal component analysis (PCA), and discriminant information was extracted by linear discriminant analysis (LDA). Last, a hybrid possibilistic clustering algorithm (HPCA) was utilized as classifier to discriminate the apple samples of different varieties. HPCA integrates possibilistic clustering algorithm (PCA) and improved possibilistic c-means (IPCM) clustering algorithm, and produces not only the membership values but also typicality values by simple computation of the sample co-variance. Experimental results showed that HPCA, as an unsupervised learning algorithm, could quickly and easily discriminate the apple varieties.
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S. Kadam, Uddhav. "Review on Real Time Data Encryption in H.264/Avc Video Streams by Exploiting IPCM Microblocks." International Journal for Research in Applied Science and Engineering Technology V, no. III (March 28, 2017): 1060–65. http://dx.doi.org/10.22214/ijraset.2017.3193.

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19

Kuo, Yao-Hung, Ji-An Liang, Guan-Heng Chen, Chia-Chin Li, and Chun-Ru Chien. "Safety of image-guided radiotherapy in definitive radiotherapy for localized prostate cancer: a population-based analysis." British Journal of Radiology 94, no. 1121 (May 1, 2021): 20200456. http://dx.doi.org/10.1259/bjr.20200456.

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Objectives: Image-guided radiotherapy (IGRT) is a recommended advanced radiation technique that is associated with fewer acute and chronic toxicities. However, one Phase III trial showed worse overall survival in the IGRT arm. The purpose of this observational study is to evaluate the impact of IGRT on overall survival. Methods: We used the Taiwan Cancer Registry Database to enroll cT1-4N0M0 prostate cancer patients who received definitive radiotherapy between 2011 and 2015. We used inverse probability treatment weighting (IPW) to construct balanced IGRT and non-IGRT groups. We compared the overall survival of those in the IGRT and non-IGRT groups. Supplementary analyses (SA) were performed with alternative covariates in propensity score (PS) models and PS approaches. The incidence rates of prostate cancer mortality (IPCM), other cancer mortality (IOCM), and cardiovascular mortality (ICVM) were also evaluated. Results: There were 360 patients in the IGRT arm and 476 patients in the non-IGRT arm. The median follow-up time was 50 months. The 5-year overall survival was 88% in the IGRT arm and 86% in the non-IGRT arm (adjusted hazard ratio [HR] of death = 0.93; 95% CI, 0.61–1.45; p = 0.77). The SA also showed no significant differences in the overall survival between those in the IGRT and non-IGRT arms. Both groups did not significantly differ in terms of IPCM, IOCM, and ICVM. Conclusions: The overall survival of localized prostate cancer patients who underwent IGRT was not inferior to those who did not. Advances in knowledge: We demonstrated that the overall survival for prostate cancer patients with IGRT was not worse than those who did not undergo IGRT; this important outcome comparison has not been previously examined in the general population.
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Santos, Myrian Sepúlveda dos. "História e Memória: o caso do Ferrugem." Revista Brasileira de História 23, no. 46 (2003): 271–95. http://dx.doi.org/10.1590/s0102-01882003000200012.

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O objetivo deste artigo é analisar o uso da memória pelas Ciências Sociais a partir da investigação de fontes orais e escritas. Ao longo do trabalho, serão consideradas cinco narrativas sobre o assassinato de um lavrador da Ilha Grande por um grupo de presos que havia fugido do Instituto Penal Cândido Mendes (IPCM). Além disso, são objetos de análise a notícia sobre o caso que aparece na imprensa e o relatório oficial sobre a fuga dos presos encaminhado pelo diretor da penitenciária ao diretor-geral do Departamento do Sistema Penitenciário (DESIPE). Em que pese a diferença entre os relatos apresentados, procurar-se-á mostrar que as memórias relacionam-se a perspectivas e códigos existentes entre grupos de pertencimento e que elas podem fornecer dados importantes sobre contextos, processos e conflitos sociais que fazem parte da vida dos diversos narradores do caso em questão.
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Roohi, Hossein, Ali Reza Noruozi, Sirous Salemi, and Jeela Sharaki. "Theoretical study of solvent effects on the conformational preference in CH2FWH (W=O, S) using PCM and IPCM methods." Journal of Molecular Liquids 143, no. 2-3 (October 2008): 119–24. http://dx.doi.org/10.1016/j.molliq.2008.06.020.

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Ren, Hongjiang, Wenliang Wang, Weina Wang, and Ni Wei. "A Theoretical Investigation on N7(H)→N9(H) Tautomerization of Isolated and Monohydrated 2,6-Dithiopurine Combined with IPCM Solvent Model." Chinese Journal of Chemistry 28, no. 6 (July 1, 2010): 1027–33. http://dx.doi.org/10.1002/cjoc.201090161.

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Petkar, Imran, Alex Dunlop, Dualta McQuaid, and Christopher Nutting. "An in silico comparative planning study investigating the predicted benefit of dysphagia-optimised volumetric arc therapy (Do-VMAT), relative to standard VMAT (S-VMAT), to reduce radiotherapy-associated dysphagia (RAD) in oropharyngeal cancers (OPC)." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e18540-e18540. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e18540.

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e18540 Background: RAD is a significant treatment-related functional morbidity in OPC and is associated with irradiation of the pharyngeal constrictor muscle (PCM). This study investigated whether a novel PCM-sparing Do-VMAT technique reduced the risk of RAD, compared to S-VMAT. Methods: Twenty OPC patients who previously underwent radiotherapy (RT) to bilateral neck were selected for this retrospective study. For each patient, S-VMAT and Do-VMAT plans were created. In both arms, the mucosal and nodal tumour received 65 Gy while the remaining oropharynx and at-risk nodal levels received 54 Gy; delivered in 30 fractions over 6 weeks. For Do-VMAT, a mandatory mean dose constraint of < 50 Gy to the volume of the combined superior (SPCM) and middle PCM (MPCM) together with an optimal dose constraint of < 20 Gy to the volume of inferior PCM (IPCM), lying outside the high-dose clinical target volume, were additionally defined and optimised to minimise PCM dose. Normal tissue complication probabilities for physician-scored RAD at 6 months (RAD6M) were determined as per the model by Christianen et al in which the 2 variables were mean dose to SPCM and supraglottic larynx (SGL). Statistical analysis was performed using paired t tests. Results: All plans had adequate target volume coverage, and dose to critical organs were within acceptable parameters. Dose to the parotid and submandibular glands were similar between the 2 RT techniques. The mean integral dose was 110.8 Gy-litre (standard deviation 17.1) with S-VMAT and 103.4 Gy-litre (15.4) with Do-VMAT, p < 0.001. With Do-VMAT, the average of the mean dose to PCM, SPCM, MPCM, IPCM, and SGL were 9.3 Gy (1.4), 4.7 Gy (1.7), 7.4 Gy (3.6), 22.7 Gy (4.1), and 2.6 Gy (2.3) respectively lower than S-VMAT (p < 0.001 for all). The mean predicted risk for RAD6M was 31.0 % (4.4) with S-VMAT, and 23.9 % (3.8) with Do-VMAT, p < 0.001. The absolute reduction in estimated toxicity risk with Do-VMAT was > 5 %, the minimally clinically important difference, in every patient. Conclusions: Do-VMAT demonstrated clinically relevant reductions in the predicted risk of RAD, compared to S-VMAT, by reducing dose to the PCM in OPC. The clinical benefits of Do-VMAT is being prospectively evaluated in DARS (CRUK/14/014), a randomised phase III study.
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Kowalczyk, Philippe, Françoise Hippert, Nicolas Bernier, Cristian Mocuta, Chiara Sabbione, Walter Batista-Pessoa, and Pierre Noé. "Impact of Stoichiometry on the Structure of van der Waals Layered GeTe/Sb2 Te3 Superlattices Used in Interfacial Phase-Change Memory (iPCM) Devices." Small 14, no. 24 (May 14, 2018): 1704514. http://dx.doi.org/10.1002/smll.201704514.

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Wei, Xiao, Haichao Chang, Baiwei Feng, and Zuyuan Liu. "Sensitivity Analysis Based on Polynomial Chaos Expansions and Its Application in Ship Uncertainty-Based Design Optimization." Mathematical Problems in Engineering 2019 (January 23, 2019): 1–19. http://dx.doi.org/10.1155/2019/7498526.

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In order to truly reflect the ship performance under the influence of uncertainties, uncertainty-based design optimization (UDO) for ships that fully considers various uncertainties in the early stage of design has gradually received more and more attention. Meanwhile, it also brings high dimensionality problems, which may result in inefficient and impractical optimization. Sensitivity analysis (SA) is a feasible way to alleviate this problem, which can qualitatively or quantitatively evaluate the influence of the model input uncertainty on the model output, so that uninfluential uncertain variables can be determined for the descending dimension to achieve dimension reduction. In this paper, polynomial chaos expansions (PCE) with less computational cost are chosen to directly obtain Sobol' global sensitivity indices by its polynomial coefficients; that is, once the polynomial of the output variable is established, the analysis of the sensitivity index is only the postprocessing of polynomial coefficients. Besides, in order to further reduce the computational cost, for solving the polynomial coefficients of PCE, according to the properties of orthogonal polynomials, an improved probabilistic collocation method (IPCM) based on the linear independence principle is proposed to reduce sample points. Finally, the proposed method is applied to UDO of a bulk carrier preliminary design to ensure the robustness and reliability of the ship.
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Farshadfar, E., and J. Sutka. "Biplot analysis of genotype-environment interaction in durum wheat using the AMMI model." Acta Agronomica Hungarica 54, no. 4 (December 1, 2006): 459–67. http://dx.doi.org/10.1556/aagr.54.2006.4.8.

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The genotype by environment (GE) interaction is a major problem in the study of quantitative traits because it complicates the interpretation of genetic experiments and makes predictions difficult. In order to quantify GE interaction effects on the grain yield of durum wheat and to determine stable genotypes, field experiments were conducted with ten genotypes for four consecutive years in two different conditions (irrigated and rainfed) in a completely randomized block design with three replications in each environment. Combined analysis of variance exhibited significant differences for the GE interaction, indicating the possibility of stable entries. The results of additive main effect and multiplicative interaction (AMMI) analysis revealed that 12% of total variability was justified by the GE interaction, which was six times more than that of genotype. Ordination techniques displayed high differences for the interaction principal components (IPC1, IPC2 and IPC3), indicating that 92.5% of the GE sum of squares was justified by AMMI1, AMMI2 and AMMI3, i.e. 4.5 times more than that explained by the linear regression model. The results of the AMMI model and biplot analysis showed two stable genotypes with high grain yield, due to general adaptability to both rainfed and irrigated conditions, and one with specific adaptation.
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Shustov, Gennady V., and Arvi Rauk. "Dioxirane oxidation of nitrosoamines. An ab initio study." Canadian Journal of Chemistry 77, no. 1 (January 1, 1999): 74–85. http://dx.doi.org/10.1139/v98-217.

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Pathways for oxidation of the parent nitrosoamine 2, nitrosodimethylamine 3, and anti- nitrosoethylmethylamine 4 by the parent dioxirane 1 have been explored computationally using the B3LYP hybrid density functional theoretical method in conjunction with the 6-31G* and 6-311+G** basis sets. Oxygen transfer from 1 to the nitrogen of the NO group (NO oxidation), yielding nitroamines 5,7, and 10, has the lowest activation barrier (15, 12.8, and 12 kcal mol-1 for 2, 3, and anti-4, respectively). Oxidation of the amine nitrogen (N oxidation) in 2, 3 leads to nitric oxide and nitroxyl radicals 6, 8 and is characterized by the highest activation energy: 28.5 kcal mol-1 for 2, 22.3 kcal mol-1 for 3. The potential barrier to hydroxylation of the methyl groups in 3 (CH oxidation) is intermediate - ca. 19 kcal mol-1. Introduction of a methyl group to the carbon reaction centre decreases the activation barrier of the anti-CH oxidation by 2-3 kcal mol-1. In 3, a gas-phase small preference for anti-CH oxidation over syn-CH oxidation, 0.1 kcal mol-1, is predicted to increase dramatically to 4.7 kcal mol-1 when the reaction is carried out in a dielectric medium (acetone, IPCM model). In general, polar solvents (CH2Cl2, acetone) lower the activation barriers for the NO, N, and CH oxidations, more so for the species of higher polarity than those of lower polarity (reactive complexes (1+3), (1+anti-4), transition state anti,syn-TSCH(1+4)]. However, the chemoselectivity (EaNO <Eaanti-CH <Easyn-CH <EaN) in the polar solvents is predicted to be the same as in the gas phase.Key words: dioxirane, nitrosoamines, oxidation, ab initio, omputation.
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Vallati, Mauro, Lukas Chrpa, Marek Grześ, Thomas Leo McCluskey, Mark Roberts, Scott Sanner, and Managing Editor. "The 2014 International Planning Competition: Progress and Trends." AI Magazine 36, no. 3 (September 28, 2015): 90–98. http://dx.doi.org/10.1609/aimag.v36i3.2571.

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We review the 2014 International Planning Competition (IPC-2014), the eighth in a series of competitions starting in 1998. IPC-2014 was held in three separate parts to assess state-of-the-art in three prominent areas of planning research: the deterministic (classical) part (IPCD), the learning part (IPCL), and the probabilistic part (IPPC). Each part evaluated planning systems in ways that pushed the edge of existing planner performance by introducing new challenges, novel tasks, or both. The competition surpassed again the number of competitors than its predecessor, highlighting the competition’s central role in shaping the landscape of ongoing developments in evaluating planning systems.
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ŻYLICZ, Tomasz. "IPCC." AURA 1, no. 4 (April 5, 2015): 29. http://dx.doi.org/10.15199/2.2015.4.7.

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30

Chen, Y., B. W. Wah, and C. Hsu. "Temporal Planning using Subgoal Partitioning and Resolution in SGPlan." Journal of Artificial Intelligence Research 26 (August 6, 2006): 323–69. http://dx.doi.org/10.1613/jair.1918.

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In this paper, we present the partitioning of mutual-exclusion (mutex) constraints in temporal planning problems and its implementation in the SGPlan4 planner. Based on the strong locality of mutex constraints observed in many benchmarks of the Fourth International Planning Competition (IPC4), we propose to partition the constraints of a planning problem into groups based on their subgoals. Constraint partitioning leads to significantly easier subproblems that are similar to the original problem and that can be efficiently solved by the same planner with some modifications to its objective function. We present a partition-and-resolve strategy that looks for locally optimal subplans in constraint-partitioned temporal planning subproblems and that resolves those inconsistent global constraints across the subproblems. We also discuss some implementation details of SGPlan4, which include the resolution of violated global constraints, techniques for handling producible resources, landmark analysis, path finding and optimization, search-space reduction, and modifications of Metric-FF when used as a basic planner in SGPlan4. Last, we show results on the sensitivity of each of these techniques in quality-time trade-offs and experimentally demonstrate that SGPlan4 is effective for solving the IPC3 and IPC4 benchmarks.
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31

Balalic, Igor, Jovan Crnobarac, and Vladimir Miklic. "Interaction hybrid × planting date for oil yield in sunflower." Journal of Agricultural Sciences, Belgrade 55, no. 1 (2010): 9–16. http://dx.doi.org/10.2298/jas1001009b.

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The aim of the study was to assess the effects of hybrids and planting dates as well as their interaction on oil yield in sunflower for three-year experiment (2005, 2006, 2007). Three sunflower hybrids (Miro, Rimi and Pobednik) and eight planting dates were included in the experiment. AMMI (Additive Main Effects and Multiplicative Interaction) analysis is one of the mainly used multiplicative models, which evaluates main effects and also interaction. The interaction was detected by using AMMI1 biplot. Oil yield was predominantly influenced by the year of growing (58.9%), then by planting date (12.9%) and by hybrid (10.7%). All interactions were significant as well. AMMI ANOVA showed high significance of both IPC1 and IPC2. The contribution of IPC1 was 77.5%. Hybrids Miro and Pobednik showed no significant differences in the mean values, which were higher than average. However, the hybrid Miro showed the highest stability for oil yield. Hybrid Rimi, with the lowest mean value, was the most unstable for the examined character. Oil yield was higher in earlier than in later planting dates. Graphical presentation of AMMI1 in the form of biplot could facilitate the choice of stable hybrids and planting dates for desired characters in sunflower.
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Brooks, Thomas M., John F. Lamoreux, and Jorge Soberón. "IPBES ≠ IPCC." Trends in Ecology & Evolution 29, no. 10 (October 2014): 543–45. http://dx.doi.org/10.1016/j.tree.2014.08.004.

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33

Gulledge, Jay. "Pocket IPCC." Nature Climate Change 1, no. 811 (October 9, 2008): 144–45. http://dx.doi.org/10.1038/climate.2008.109.

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34

Szweda, Roy, and Joe Lorenzo. "IPRM'94." III-Vs Review 7, no. 6 (December 1994): 8. http://dx.doi.org/10.1016/0961-1290(94)90097-3.

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35

Szweda, Roy. "IPRM report." III-Vs Review 7, no. 3 (June 1994): 24. http://dx.doi.org/10.1016/0961-1290(94)90307-7.

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36

Vargas-Castrillón, Silvia, and Francisco Cutanda. "[P123] Reference dosimetry in flattening filter-free beams: Experience with IPSM-1990/IPEM Topical Report 1–2016 and IAEA TRS-398." Physica Medica 52 (August 2018): 135. http://dx.doi.org/10.1016/j.ejmp.2018.06.436.

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37

Berger, D. "Laparoskopische IPOM-Technik." Der Chirurg 81, no. 3 (February 17, 2010): 211–15. http://dx.doi.org/10.1007/s00104-009-1819-4.

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38

Khmelnitskiy, I. K., V. M. Aivazyan, N. I. Alekseyev, A. P. Broyko, V. V. Gorodilov, V. E. Kalyonov, A. V. Korlyakov, A. V. Lagosh, V. V. Luchinin, and D. O. Testov. "Actuating IPMC Tranducers with Feedback System Based on IPMC Sensor." Nano- i Mikrosistemnaya Tehnika 21, no. 2 (February 20, 2019): 111–20. http://dx.doi.org/10.17587/nmst.21.111-120.

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39

Ishiki, Asuka, Hiroyuki Nabae, Akio Kodaira, and Koichi Suzumori. "PF-IPMC: Paper/Fabric Assisted IPMC Actuators for 3D Crafts." IEEE Robotics and Automation Letters 5, no. 3 (July 2020): 4035–41. http://dx.doi.org/10.1109/lra.2020.2985571.

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40

Park, Il-Soo, Yu Woon, Kyung-Won Chung, Gangwoong Lee, Jeffrey S. Owen, Won-Tae Kwon, and Won-Tae Yun. "In-depth Review of IPCC 5th Assessment Report." Journal of Korean Society for Atmospheric Environment 30, no. 2 (April 30, 2014): 188–200. http://dx.doi.org/10.5572/kosae.2014.30.2.188.

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41

Bozovic, Dragan, Tomislav Zivanovic, Vera Popovic, Mladen Tatic, Zagorka Gospavic, Zoran Miloradovic, Goran Stankovic, and Milorad Djokic. "Assessment stability of maize lines yield by GGE-biplot analysis." Genetika 50, no. 3 (2018): 755–70. http://dx.doi.org/10.2298/gensr1803755b.

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Maize genotypes have varied reactions in different localities, years, treatments or the combination of these factors, due to genotype x year interaction. The objective of this study was to estimate genotype by locality, by year, by treatments (G?L?Y?T) interaction using AMMI model, to identify maize genotypes with stable and high yield performance in different growing seasons. The trials with seven maize lines/genotypes were conducted during two years (2010-2011) at the four treatments and two locations: Pan?evo and Zemun Polje. The results showed that the influence of: genotype (G), locality (L), treatment (T) and G?L, G?T, Y?L, Y?T, L?T, G?Y?T, G?L?T, Y?L?T, G?Y?L?T interaction, on maize yield were significant (p<0.01). The share of genotype for maize grain yield in the total phenotypic variance was 21.16%, the aggregate share of the years and the locality was 6.10%, the treatment was 18.22%, and the total interaction was 54.52%. The AMMI analysis of the main components of IPCA1 and IPCA2 for the interaction of G?L and G?T shows that the first major component, IPCA1, comprises 100% of the sum of the squared interaction G?L and showed a statistically significant effect. The results also show that the sums of the squares of the first and second major components (PC1 and PC2) constitute 100% of the sum of the squared interaction G?L. The IPCA1 share in the G?T interaction was 47.39% and the IPC2 was 37.94%. IPC1 and IPC2 for this interaction was 85.33%. A high level of IPC2 indicates a significant treatment effect. The results of AMI analysis show that there is a significant difference between the genotype reactions to different ecological conditions for investigated factors. It also provided better insight in specific association between maize grain yield, locality, treatment and meteorological variables. Among the tested maize lines/genotypes, L-5, L-4 and L-6 could be separated as highest yielding genotypes, however L-5 could be recommended for further breeding program and in large-scale seed production due to its stable and high yielding performance.
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42

Shahinpoor, Mohsen. "Chitosan/IPMC Artificial Muscles." Advances in Science and Technology 79 (September 2012): 32–40. http://dx.doi.org/10.4028/www.scientific.net/ast.79.32.

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This presentation discusses how biopolymers such as chitosan and ionic polymer metal composites (IPMCs) can be combined by intercalation and co-polymerization to form a new nanocomposite with actuation, energy harvesting and sensing capabilities and yet have medical healing and diagnostics capabilities. Described are chitosan and ionic polymeric networks containing conjugated ions that can be redistributed by an imposed electric field and consequently act as distributed nanosensors, nanoactuators and artificial muscles. The presentation briefly discusses the manufacturing methodologies and the fundamental properties and characteristics of such chitosan/ionic polymers as distributed nanosensors, nanoactuators and artificial muscles. It will further include descriptions of the basic materials' typical molecular structures. An ionic model based on charge dynamics of the underlying sensing and actuation mechanisms is also presented. Intercalation of chitosan biopolymer and ionic polymers such as perfluorinated sufonic ionomers and subsequent chemical plating of them with a noble metal by a REDOX operation is also reported and the properties of the new product are briefly discussed.
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43

Dai, Pengxiu, Jiakai Li, Yijing Chen, Luwen Zhang, Xinke Zhang, Jinglu Wang, Guixiang Qi, and Yihua Zhang. "Novel Functional Genes Involved in Transdifferentiation of Canine ADMSCs Into Insulin-Producing Cells, as Determined by Absolute Quantitative Transcriptome Sequencing Analysis." Frontiers in Cell and Developmental Biology 9 (June 28, 2021). http://dx.doi.org/10.3389/fcell.2021.685494.

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The transdifferentiation of adipose-derived mesenchymal stem cells (ADMSCs) into insulin-producing cells (IPCs) is a potential resource for the treatment of diabetes. However, the changes of genes and metabolic pathways on the transdifferentiation of ADMSCs into IPCs are largely unknown. In this study, the transdifferentiation of canine ADMSCs into IPCs was completed using five types of procedures. Absolute Quantitative Transcriptome Sequencing Analysis was performed at different stages of the optimal procedure. A total of 60,151 transcripts were obtained. Differentially expressed genes (DEGs) were divided into five groups: IPC1 vs. ADSC (1169 upregulated genes and 1377 downregulated genes), IPC2 vs. IPC1 (1323 upregulated genes and 803 downregulated genes), IPC3 vs. IPC2 (722 upregulated genes and 680 downregulated genes), IPC4 vs. IPC3 (539 upregulated genes and 1561 downregulated genes), and Beta_cell vs. IPC4 (2816 upregulated genes and 4571 downregulated genes). The gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of DEGs revealed that many genes and signaling pathways that are essential for transdifferentiation. Hnf1B, Dll1, Pbx1, Rfx3, and Foxa1 were screened out, and the functions of five genes were verified further by overexpression and silence. Foxa1, Pbx1, and Rfx3 exhibited significant effects, can be used as specific key regulatory factors in the transdifferentiation of ADMSCs into IPCs. This study provides a foundation for future work to understand the mechanisms of the transdifferentiation of ADMSCs into IPCs and acquire IPCs with high maturity.
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44

"IPCM '97." European Polymer Journal 32, no. 7 (July 1996): II. http://dx.doi.org/10.1016/0014-3057(96)80017-6.

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45

R., Silambarasan, Veerappan A.R., and Shanmugam S. "Effect of structural deformations and bend angle on the collapse load of pipe bends subjected to in-plane closing bending moment." World Journal of Engineering ahead-of-print, ahead-of-print (July 1, 2021). http://dx.doi.org/10.1108/wje-03-2021-0122.

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Purpose The purpose of this study is to investigate the effect of structural deformations and bend angle on plastic collapse load of pipe bends under an in-plane closing bending moment (IPCM). A large strain formulation of three-dimensional non-linear finite element analysis was performed using an elastic perfectly plastic material. A unified mathematical solution was proposed to estimate the collapse load of pipe bends subjected to IPCM for the considered range of bend characteristics. Design/methodology/approach ABAQUS was used to create one half of the pipe bend model due to its symmetry on the longitudinal axis. Structural deformations, i.e. ovality (Co) and thinning (Ct) varied from 0% to 20% in 5% steps while the bend angle (ø) varied from 30° to 180° in steps of 30°. Findings The plastic collapse load decreases as the bend angle increase for all pipe bend models. A remarkable effect on the collapse load was observed for bend angles between 30° and 120° beyond which a decline was noticed. Ovality had a significant effect on the collapse load with this effect decreasing as the bend angle increased. The combined effect of thinning and bend angle was minimal for the considered models and the maximum per cent variation in collapse load was 5.76% for small bend angles and bend radius pipe bends and less than 2% for other cases. Originality/value The effect of structural deformations and bend angle on collapse load of pipe bends exposed to IPCM has been not studied in the existing literature.
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46

Petkar, Imran, Dualta McQuaid, Alex Dunlop, Justine Tyler, Emma Hall, and Chris Nutting. "Inter-Observer Variation in Delineating the Pharyngeal Constrictor Muscle as Organ at Risk in Radiotherapy for Head and Neck Cancer." Frontiers in Oncology 11 (March 9, 2021). http://dx.doi.org/10.3389/fonc.2021.644767.

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Background and PurposeTo evaluate the inter-observer variation (IOV) in pharyngeal constrictor muscle (PCM) contouring, and resultant impact on dosimetry and estimated toxicity, as part of the pre-trial radiotherapy trial quality assurance (RTQA) within DARS, a multicenter phase III randomized controlled trial investigating the functional benefits of dysphagia-optimized intensity-modulated radiotherapy (Do-IMRT) in pharyngeal cancers.Methods and MaterialsOutlining accuracy of 15 clinicians’ superior and middle PCM (SMPCM) and inferior PCM (IPCM) were retrospectively assessed against gold standards (GS) using volume, location, and conformity indices (CIs) on a pre-trial benchmark case of oropharyngeal cancer. The influence of delineation variability on dose delivered to the constrictor muscles with Do-IMRT and resultant normal tissue complication probability (NTCP) for physician-scored radiation-associated dysphagia at 6 months was evaluated.ResultsFor GS, SMPCM, and IPCM volumes were 13.51 and 1.67 cm3; corresponding clinician mean volumes were 12.18 cm3 (SD 3.0) and 2.40 cm3 (SD 0.9) respectively. High IOV in SMPCM and IPCM delineation was observed by the low DICE similarity coefficient value, along with high geographical miss index and discordance index values. Delineation variability did not significantly affect the mean dose delivered to the constrictors, relative to the GS plan. Mean clinician NTCP was 24.6% (SD 0.6), compared to the GS-NTCP of 24.7%.ConclusionsResults from this benchmark case demonstrate that inaccurate PCM delineation existed, even with protocol guidelines. This did not impact on delivered dose to this structure with Do-IMRT, or on estimated swallowing toxicity, in this single benchmark case.
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47

Eldahshan, Omayma A. "Fighting Cancer by Phytochemicals." International Journal of Pharmacognosy & Chinese Medicine 1, no. 1 (2017). http://dx.doi.org/10.23880/ipcm-16000101.

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48

Shah, Sandeep. "Commentary on Therapeutic Role of Ginger (Zingiber officinale) as Medicine for the Whole World." International Journal of Pharmacognosy & Chinese Medicine 1, no. 1 (2017). http://dx.doi.org/10.23880/ipcm-16000102.

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49

Fiky, Fathy K. El. "Chemical Composition and Biological Activity of Essential Oil from Cotula cinerea (Del.) Growing Wildly in the Middle East: A Short Review." International Journal of Pharmacognosy & Chinese Medicine 1, no. 1 (2017). http://dx.doi.org/10.23880/ipcm-16000103.

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50

Bhagvat, Pranav. "Scientific Research-How True it is?" International Journal of Pharmacognosy & Chinese Medicine 1, no. 1 (2017). http://dx.doi.org/10.23880/ipcm-16000104.

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