Academic literature on the topic 'Intraocular pressure'

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Journal articles on the topic "Intraocular pressure"

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M.N., Nandita, R. H. Taklikar, Anupama H. Taklikar, and Anant A. Takalkar. "Intraocular Pressure Changes in Smokers." International Physiology 5, no. 1 (2017): 19–22. http://dx.doi.org/10.21088/ip.2347.1506.5117.4.

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Faruqi, Muhammad Shahid Faruqi, Abdul Rehman Khokhar, Abdul Ghaffar Khan, and Tanvir Ali Shirwany. "INTRAOCULAR PRESSURE." Professional Medical Journal 23, no. 03 (March 10, 2016): 317–23. http://dx.doi.org/10.29309/tpmj/2016.23.03.1481.

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Objectives: To evaluate the intraocular pressure in diabeto-hypertensivesubjects and age and sex matched normal healthy adults. Study Design: Cross-sectionalanalytic study. Methodology: 50 subjects visiting the out-patient department (OPD) ofOphthalmology in Lahore General Hospital, Lahore, were examined. 25 were newly diagnoseddiabeto-hypertensive, and 25 normal healthy were selected from the relatives of these patients.IOP was checked by Goldman Applanation Tonometer. Blood pressure was checked bymercury sphygmomanometer. Blood glucose level checked by glucometer. Results: The IOPwas raised in both eyes of diabeto-hypertensive patients and there was a significant differencein intraocular pressure of normal healthy control and diabeto-hypertensive subjects. Thedifferences between two groups was analyzed by paired Student’s t-test. The P-value was<0.001. Conclusion: Intra-ocular pressure can be raised in all diabeto-hypertensive subjects,which shows that co-existence of diabetes and hypertension were important risk factor forraised intraocular pressure.
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Ahmad, Munir, Iftikhar Ahmed, Waqar Ahmed, and ZulfiqarUddin Syed. "INTRAOCULAR PRESSURE." Professional Medical Journal 21, no. 01 (December 5, 2018): 157–62. http://dx.doi.org/10.29309/tpmj/2014.21.01.1915.

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Objective: To assess the incidence of steroid induced rise in intra-ocular pressurein different group of patients. Place and duration of study: The study was conducted in thedepartment of ophthalmology Akhtar Saeed Trust Teaching Hospital of Akhtar Saeed Medicaland Dental College Lahore and Continental Medical College Lahore from Jan 2009 to Oct 2010.Material and Methods: Three groups were formulated in which group A comprised of normalpopulation with no ocular disease, group B included patients with vernal keratoconjunctivitiswhile group C comprised of chronic simple glaucoma patients with controlled intraocularpressure. Dexamethasone 0.1% eye drops were used four times daily for four weeks and patientswere evaluated weekly in terms of IOP monitoring after which they were labeled as either low ornon-responders, moderate responders or high responders. Results: In group A 40% of thepatients showed rise in IOP, group B showed 95% rise in IOP and the response in group C caseswas 100%. Conclusions: Topical steroids result in significant rise in IOP therefore carefulmonitoring should be done in all patients on corticosteroids.
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Rao, Aparna. "Intraocular Pressure." Journal of Glaucoma 24, no. 3 (March 2015): 251–52. http://dx.doi.org/10.1097/ijg.0000000000000181.

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Guzmán, Andrés Fernando, Alejandro Arciniegas Castilla, Fabio Ariel Guarnieri, and Fernando Ramírez Rodríguez. "Intraocular Pressure." Journal of Glaucoma 22, no. 1 (January 2013): 10–14. http://dx.doi.org/10.1097/ijg.0b013e31822f4747.

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Kosoko, Omofolasade, Roger P. Mason, Claude L. Cowan, and James Gear. "INTRAOCULAR PRESSURE." Southern Medical Journal 83, Supplement (September 1990): 2S—41. http://dx.doi.org/10.1097/00007611-199009001-00160.

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Murgatroyd, Harry, and Jane Bembridge. "Intraocular pressure." Continuing Education in Anaesthesia Critical Care & Pain 8, no. 3 (June 2008): 100–103. http://dx.doi.org/10.1093/bjaceaccp/mkn015.

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Cheng, T. O. "Intraocular pressure." Postgraduate Medical Journal 67, no. 791 (September 1, 1991): 856–57. http://dx.doi.org/10.1136/pgmj.67.791.856-a.

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M.B, Pushpa, and Varsha Vijay AKhade A.V. "Study of Intraocular Pressure (IOP) Changes in Relation Blood Pressure." International Physiology 5, no. 2 (2017): 107–9. http://dx.doi.org/10.21088/ip.2347.1506.5217.12.

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Green, Keith, David Harman, and Lisa Cheeks. "The interrelationship between intraocular pressure and Honan Intraocular Pressure Reducer pressure." Current Eye Research 5, no. 8 (January 1986): 621–24. http://dx.doi.org/10.3109/02713688609015127.

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Dissertations / Theses on the topic "Intraocular pressure"

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Rai, Gurjeet Kaur. "Accommodation and intraocular pressure." Thesis, Aston University, 2007. http://publications.aston.ac.uk/14645/.

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The relationship between accommodation and intraocular pressure (IOP) has not been addressed as a research question for over 20 years, when measurement of both of these parameters was less advanced than today. Hence the central aim of this thesis was to evaluate the effects of accommodation on lOP. The instrument of choice throughout this thesis was the Pulsair EasyEye non-contact tonometer (NCT) due principally to its slim-line design which allowed the measurement of lOP in one eye and simultaneous stimulation of accommodation in the other eye. A second reason for using the Pulsair EasyEye NCT was that through collaboration with the manufacturers (Keeler, UK) the instrument's operational technology was made accessible. Hence, the principle components underpinning non-contact lOP measures of 0.1mmHg resolution (an order of magnitude greater than other methods) were made available. The relationship between the pressure-output and corneal response has been termed the pressure-response relationship, aspects of which have been shown to be related to ocular biometric parameters. Further, analysis of the components of the pressure-response relationship together with high-speed photography of the cornea during tonometry has enhanced our understanding of the derivation of an IOP measure with the Pulsair EasyEye NCT. The NCT samples the corneal response to the pressure pulse over a 19 ms cycle photoelectronically, but computes the subject's lOP using the data collected in the first 2.34 ms. The relatively instantaneous nature of the lOP measurement renders the measures susceptible to variations in the steady-state lOP caused by the respiratory and cardiac cycles. As such, the variance associated with these cycles was minimised by synchronising the lOP measures with the cardiac trace and maintaining a constant pace respiratory cycle at 15 breathes/minute. It is apparent that synchronising the lOP measures with the peak, middle or trough of the cardiac trace significantly reduced the spread of consecutive measures. Of the 3 locations investigated, synchronisation with the middle location demonstrated the least variance (coeflicient of variation = 9.1%) and a strong correlation (r = 0.90, p = <0.001) with lOP values obtained with Goldmann contact tonometry (n = 50). Accordingly IOP measures synchronised with the middle location of the cardiac cycle were taken in the RE while the LE fixated low (L; zero D), intermediate (I; 1.50 D) and high (H; 4 D) accommodation targets, Quasi-continuous measures of accommodation responses were obtained during the lOP measurement period using the portable infrared Grand Seiko FR-5000 autorefractor. The lOP reduced between L and I accommodative levels by approximately 0.61 mmHg (p <0.00 I). No significant reduction in IOP between L and H accommodation levels was elicited (p = 0.65) (n = 40). The relationship between accommodation and lOP was characterised by substantial inter-subject variations. Myopes demonstrated a tendency to show a reduction in IOP with accommodation which was significant only with I accommodation levels when measured with the NCT (r = 0.50, p = 0.01). However, the relationship between myopia and lOP change with accommodation reached significance for both I (r = 0.61, p= 0.003) and H (r = 0.531, p= 0.0 1) accommodation levels when measured with the Ocular blood Flow Analyser (OBFA). Investigation of the effects of accommodation on the parameters measured by the OBFA demonstrated that with H accommodation levels the pulse amplitude (PA) and pulse rate (PR) responses differed between myopes and emmetropes (PA: p = 0.03; PR: p = 0.004). As thc axial length increased there was a tendency for the pulsatile ocular blood flow (POBF) to reduce with accommodation, which was significant only with H accommodation levels (r = 0.38, p = 0.02). It is proposed that emmetropes arc able to regulate the POBF responses to changes in ocular perfusion pressure caused by changes in lOP with I (r = 0.77, p <0.001) and H (r = 0.73, p = 0.001) accommodation levels. However, thc relationship between lOP and POBF changes in the myopes was not correlated for both I (r = 0.33, p = 0.20) and H (r = 0.05, p = 0.85) accommodation levels. The thesis presents new data on the relationships between accommodation, lOP and parameters of the OBFA,: and provides evidence for possible lOP and choroidal blood flow regulatory mechanisms. Further the data highlight possible deficits in the vascular regulation of the myopic eye during accommodation, which may play a putative role in the aetiology of myopia development.
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Johansson, Gabriella. "Effect of phacoemulsification on intraocular pressure." Thesis, Linnéuniversitetet, Institutionen för naturvetenskap, NV, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-12619.

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Aim: The purpose of this study was to evaluate whether there is an effect of cataractsurgery with phacoemulsification on IOP after one week of surgery. To investigate whether there is a correlation between Axial length (AL), Anterior chamber depth ACD, K-readings with preoperative (preop) and postoperative (postop) IOP. Methods: The subjects for this study were extracted from the records at the Eye department in Kalmar Hospital, Sweden. From an existing data file 72 eyes out of 72 subjects were then analysed. The subjects were divided into 4 groups based on the axial length of the eyes, forstatistical analysis in Microsoft Excel and Statistica 6.0. Preoperative and postoperative IOP was evaluated to look for statistical significance. IOP was compared to AL, ACD and Kreadingsto look for any correlations. Results: Preoperative IOP and postoperative IOP did not show any statistically significant difference after phacoemsulification, p > 0.05. There was no statistical significance orcorrelation for the axial length, ACD and K-readings compared to pre and post IOP,p > 0.05.Conclusion: There was no change in IOP before and after surgery. This study did not show any significance between the preoperative and postoperative mean IOP after cataract surgery. Axial length was not a factor to the intraocular pressure. There was neither any statistical significance nor correlation between the anterior chamber depth and K-readings in relation to IOP.
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Morgan, Andrew J. "Analysis of the intraocular pressure pulse." Thesis, Aston University, 2003. http://publications.aston.ac.uk/14542/.

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This thesis was concerned with investigating methods of improving the IOP pulse’s potential as a measure of clinical utility. There were three principal sections to the work. 1. Optimisation of measurement and analysis of the IOP pulse. A literature review, covering the years 1960 – 2002 and other relevant scientific publications, provided a knowledge base on the IOP pulse. Initial studies investigated suitable instrumentation and measurement techniques. Fourier transformation was identified as a promising method of analysing the IOP pulse and this technique was developed. 2. Investigation of ocular and systemic variables that affect IOP pulse measurements In order to recognise clinically important changes in IOP pulse measurement, studies were performed to identify influencing factors. Fourier analysis was tested against traditional parameters in order to assess its ability to detect differences in IOP pulse. In addition, it had been speculated that the waveform components of the IOP pulse contained vascular characteristic analogous to those components found in arterial pulse waves. Validation studies to test this hypothesis were attempted. 3. The nature of the intraocular pressure pulse in health and disease and its relation to systemic cardiovascular variables. Fourier analysis and traditional parameters were applied to the IOP pulse measurements taken on diseased and healthy eyes. Only the derived parameter, pulsatile ocular blood flow (POBF) detected differences in diseased groups. The use of an ocular pressure-volume relationship may have improved the POBF measure’s variance in comparison to the measurement of the pulse’s amplitude or Fourier components. Finally, the importance of the driving force of pulsatile blood flow, the arterial pressure pulse, is highlighted. A method of combining the measurements of pulsatile blood flow and pulsatile blood pressure to create a measure of ocular vascular impedance is described along with its advantages for future studies.
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Hallberg, Per. "Applanation Resonance Tonometry for Intraocular Pressure Measurement." Doctoral thesis, Umeå : Tillämpad fysik och elektronik, Umeå univ, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-784.

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Chang, Jason (Yin-Hao). "Mechano-regulation of intraocular pressure through eNOS." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/58342.

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Glaucoma is the leading cause of irreversible blindness worldwide, and is characterized by elevated intraocular pressure (IOP) caused by increased resistance to aqueous humor outflow. The majority of outflow resistance is generated near the inner wall endothelium of Schlemm’s canal (SC). The inner wall experiences a basal-to-apical directed flow as aqueous humor crosses the outflow pathway. As IOP increases, the outflow pathway responds in a pressure-dependent manner, resulting in the expansion of the trabecular meshwork (TM) and the collapse of SC. This effectively reduces the cross-sectional area of the SC lumen and increases the shear stress experienced by SC cells, reaching levels known to activate endothelial nitric oxide synthase (eNOS) in vascular endothelia. Our central hypothesis examines the role of eNOS as part of a dynamic mechano-regulatory feedback system to regulate the outflow resistance sites through nitric oxide (NO) production to maintain IOP homeostasis. We firstly demonstrated the physiological role of NO and eNOS in regulating aqueous humor outflow through the use of NO-donor and NOS-inhibitors. We also demonstrated that spatial variations in eNOS expression in the SC correlates with regions of greater outflow in the TM. Furthermore, we developed NO-sensitive biosensors to detect changes in NO production in response to elevated IOP, showing that NO production was pressure-dependent. Finally, we demonstrated that targeted delivery of NO to the outflow resistance sites in the TM results in a ~3-fold increase in outflow facility. Taken together, these studies reveal that eNOS plays a crucial regulatory role in conventional outflow physiology by modulating outflow resistance through NO production. This mechano-regulatory feedback mechanism appears to be altered in glaucoma, and thus leads to ocular hypertension and pathogenesis of the disease. Therefore, targeting the NO-regulatory machinery within the outflow pathway may provide a promising therapeutic target for treating glaucoma.
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Gerzenstein, Sabrina Melisa. "Pharmacogenomics of the Intraocular Pressure Response to Glucocorticoids." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_theses/285.

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Glucocorticoids (GCs) have been widely used as a therapeutic agent for diverse inflammatory ocular diseases. However, a high percentage of patients undergoing this treatment develop high intraocular pressure (IOP), which if left unsupervised may lead to glaucoma. It is believed that the IOP elevation in response to GC treatment has a genetic determinant. In order to test this hypothesis, we analyzed in 52 patients the presence of single nucleotide polymorphisms (SNPs) in the glucocorticoid receptor gene (GR), the principal mediator of GCs uptake by the cells. We studied six GR SNPs previously reported to be associated with sensitivity and resistance to GCs: GluArg22/23GluLys (codon 22-23), Asn363Ser (codon 363), IVS2+646C>G (intron 2/BclI), IVS3-46G>C (intron 3), IVS4-16G>T (intron 4), Asn766Asn (Codon 766). Nevertheless, the results of this preliminary study did not show any specific correlation between SNPs in the GR gene and IOP elevation. Therefore, we proceeded to perform a whole genome SNP screen with the DNA samples of these patients to search for possible target genes responsible for the elevated IOP after GC treatment. As a result, we identified forty-eight SNPs in thirty-three genes that correlate with the high IOP response. The gene showing the strongest association is a poorly known G-protein coupled receptor. In addition, four SNPs hit a single transporter gene. Other candidate genes identified are a translation elongation factor, an F-box protein, an oxysterol binding protein, and a solute carrier family gene. These results support our hypothesis that IOP elevation following GC treatment is a genetically determined response. GCs are a common treatment for innumerable medical conditions; we believe that a genetic association between GC treatment and its physiological response may be important for improving treatment management and drug development for retinal diseases as well as for other medical ailments. However, further studies need to be performed to analyze in depth the association between the candidate genes identified in this study and the steroid response.
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Jóhannesson, Gauti. "Intraocular pressure : clinical aspects and new measurement methods." Doctoral thesis, Umeå universitet, Oftalmiatrik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-40383.

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Intraocular pressure (IOP) measurement is a routine procedure and a fundament in glaucoma care. Elevated IOP is the main risk factor for glaucoma, and to date, reduction of IOP is the only possible treatment. In a retrospective clinical material, the prevalence of open angle glaucoma was estimated on the west coast of Iceland. IOP measurement and optic nerve head examination were used to capture glaucoma suspects, within the compulsory ophthalmological examination for the prescription of eye glasses. The results were mainly in agreement with a recent prospective study in the same region. This indicated that retrospective data, under certain conditions, may contribute with useful information on the prevalence of glaucoma. However, normal tension glaucoma is underestimated if perimetry and/or fundus photography are not included in the examination. Three studies focused on the measurement of IOP. Goldmann applanation tonometry (GAT) is the standard method. GAT is affected by corneal properties, e.g. central corneal thickness (CCT) and corneal curvature (CC). Refractive surgery changes these properties. This has put focus on how corneal biomechanics translate into tonometric errors and stimulated the development of new methods. As a result, Pascal ® Dynamic Contour Tonometry (PDCT) and Icare® rebound tonometry have been introduced. A method under development by our research group is Applanation Resonance Tonometry (ART). It is based on resonance technology and estimates IOP from continuous measurement of force and contact area. Comparison of PDCT, Icare and GAT in a prospective study showed that the concordance to GAT was close to the limits set by the International Standard Organization (ISO) for PDCT, while Icare was outside the limits. To investigate if laser-assisted subepithelial keratectomy (LASEK) affects tonometry, a study was performed where measurements with GAT, PDCT and ART were obtained before, three and six months after LASEK. The hypothesis was that PDCT and ART would be less affected by LASEK than GAT. The results showed a statistically significant reduction of measured IOP three and six months after LASEK for all tonometry methods. Change in visual acuity and IOP between three and six months suggested a prolonged postoperative process. A servo-controlled prototype (ART servo) was developed. A study was undertaken to assess the agreement of ARTservo and a further developed v manual prototype (ART manual) with GAT. The study design was in accordance with the requirements of the ISO standard for tonometers. ARTmanual fulfilled the precision requirements of the ISO standard. ARTservo did not meet all the requirements of the standard at the highest pressure levels. Four tonometry methods, GAT, PDCT, Icare and ART, were investigated. None of them was independent of both CCT and CC. The inconsistencies in the results emphasize the importance of study design. A meta-analysis comprising healthy eyes (IOP ≤ 21 mmHg) in the three papers, revealed age as an important confounder. In summary, glaucoma prevalence in Iceland was investigated and the results indicated that a retrospective approach can contribute with meaningful information. ART and PDCT had a similar agreement to GAT. ART manual fulfilled the precision requirements set by the ISO-standard, ARTservo and PDCT were close, while Icare was distinctly outside the limits. All tonometry methods were affected by LASEK and no method was completely independent of corneal properties.
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Bello, Simon Antonio. "Intraocular Pressure Sensing and Control for Glaucoma Research." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6466.

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Animal models of ocular hypertension are important for glaucoma research but come with experimental costs. Available methods of intraocular pressure (IOP) elevation are not always successful, the amplitude and time course of IOP changes are unpredictable and irreversible, and IOP measurement by tonometry is laborious. This dissertation focuses on the development and implementation of two novel systems for monitoring and controlling IOP without these limitations. The first device consists of a cannula implanted in the anterior chamber of the eye, a pressure sensor that continually measures IOP, and a bidirectional pump driven by control circuitry that can infuse or withdraw fluid to hold IOP at user-desired levels. A portable version was developed for tethered use on rats. The system was fully characterized and deemed ready for cage- or bench-side applications. The results lay the foundation for an implantable version that would give glaucoma researchers unparalleled knowledge and control of IOP in rats and potentially larger animals. Moreover, a novel mathematical technique was developed to efficiently analyze IOP records obtained using the pressure controlling device. The algorithm successfully yields the value of several parameters that influence ocular physiology and are commonly linked to glaucoma development. This unique methodology uses information regarding the amount of volume necessary to maintain IOP at different levels to quantify the outflow facility of perfused eyes. The use of this technology largely simplifies the investigator’s experimental set-up and cuts procedural times in half. The second device is an implantable pressure sensor for continuously monitoring IOP. The miniature system is equipped with pressure and temperature transducers, on-board amplifiers and a powerful microcontroller that ensure data quality. The sensor is able to obtain measurements with twice the accuracy and precision of any other IOP sensor used to date, avoid electronic drifts commonly seen in commercial sensing devices, and can potentially be used in a variety of animal models. The sensor was characterized and tested in alert rats for weeks on end. Data obtained with this device showed the presence of previously reported circadian rhythms, with IOP significantly increasing during nocturnal cycles. This technology provides researchers with an unprecedented tool to analyze IOP dynamics over time. The characterization of the amplitude, period and phase of the IOP profiles of normal and glaucomatous eyes may help establish a definitive correlation between ocular hypertension and glaucoma progression. While implantable systems provide investigators with essential physiological data, their implementation can be difficult. Challenges such as reduced operational lifetimes and limited data acquisition capabilities are commonly faced by most bio-devices. These limitations are frequently linked to small battery capacities, however the implementation of bigger batteries is not usually viable due to size requirements. Energy harvesting technologies have surfaced in recent years in an attempt to replace battery applications; however, most technologies provide low power densities and cannot deliver continuous telemetric operation. An innovative wireless powering system was developed to overcome these limitations. The technology uses radio frequency (RF) energy transfer to continuously harvest high energy levels. Taking advantage of the controlled environment under which most research animals are housed, RF transmitters are placed around the cage to form strong, omnidirectional electric fields. An especial antenna was designed to be worn by the animal and collect large energy levels, irrespective of animal movements and positioning. The system was tested on the implantable IOP sensor for weeks, providing robust performances and allowing the sensor to collect data continuously with high precision. The device consistently generated power densities much greater than those required by the sensor. The surplus of energy could be used to operate multiple sensors simultaneously, greatly increasing the investigator’s leverage. The technology is easily adaptable to other bio-sensors and has the potential to revolutionize the biomedical field.
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Polyzoev, Vasco. "HAND-HELD TONOMETER FOR TRANSPALPEBRAL INTRAOCULAR PRESSURE MEASUREMENT." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/202517.

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This dissertation describes the development of a portable, hand-held tonometer for measurement of the intraocular pressure through the eyelid. The primary use of such device will be by people diagnosed with the eye disease glaucoma. Glaucoma is the second leading cause of blindness in the world and is asymptomatic to the patient in its early stages. This allows it to remain undiagnosed for prolonged periods, causing irreversible damage to the affected person's vision. Elevated intraocular pressure is the main risk factor associated with the development of glaucoma, and is currently the only symptom that is treatable for the slowing down or stopping of the progression to blindness caused by the disease. The effectiveness of the medications or procedures aimed at reducing the pressure to below risk levels is currently monitored through visits to the ophthalmologists' offices, which makes the frequent monitoring of the pressure inconvenient, expensive and sometimes impossible. Due to the variation of the pressure throughout the day and during different activities or food and beverage intake, the portability of the device is important in order to allow the user to carry it with them and take measurements as frequent as needed. The option to perform the measurement through the eyelid avoids direct contact with the eye, eliminating possible discomfort, the use of anesthetics, and the risk of contamination.Several designs and measuring concepts are evaluated using a custom made pressure regulation system. A series of prototypes have been built and tested and the results are reported in the respective sections of the dissertation. The final concept selected for the measurement technique was based on multiple force probe indentation and a custom MEMS-based force sensor for it was designed and tested.The main contributions of this dissertation are the design, fabrication and test of the prototype devices and the MEMS force sensors. The obtained results and experience described here can serve as a platform for further optimization and improvement of the device, and eventual development of a prototype capable of performing clinical research studies and passing FDA approval for home and clinical use.
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Ljubimova, Darja. "Biomechanics of the Human Eye and Intraocular Pressure Measurements." Doctoral thesis, KTH, Strukturmekanik, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-11420.

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This thesis addresses the reliability of Goldmann-type applanation tonometers (GAT). It deals with the investigation of the relation between predicted intraocular pressure, IOPG and true pressure, IOPT. The problem of the accuracy of GAT readings has acquired special importance over the last two decades as new types of surgical procedures to correct vision disorders are being explored and gain universal acceptance. The overall aim of the present study is to assess the effects of individual variations in the corneal central thickness (CCT), material properties of the involved tissues and paracentral applanation on the accuracy of IOPG. Two finite element models have been constructed: a two-dimensional axisymmetric model of the cornea and a three-dimensional model of the whole corneoscleral envelope. Various material descriptions were adopted for the cornea in 2D, whereas the 3D model accounted for collagen microstructure and represented a hyperelastic ber reinforced material. Nonlinear analyses were carried out using the commercial general-purpose finite element software ABAQUS. An extensive literature survey and consultations with ophthalmologists and clinicians were the platform for establishing relevant modelling procedures. The results reveal a clear association between all considered parameters and measured IOPG. The effect of assumed CCT is highly dependent on the corneal material properties. Material model alone has a profound effect on predicted IOPG. Variations in tonometer tip application produce clinically signi cant errors to IOPG measurements. Potential effects of corneal stiffness and paracentral applanation on GAT readings are larger than the impact of CCT. The behaviour of the models is broadly in agreement with published observations. The proposed procedures can be a useful tools for suggesting the magnitudes of corrections for corneal biomechanics and possible human errors. The present modelling exercise has an ability to reproduce the behaviour of human cornea and trace it under IOP and GAT, providing potentially useful information on the distribution of stresses and strains. Some recommendations can be drawn in pursuit of the clinical imperatives of ophthalmologists.
QC 20100729
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Books on the topic "Intraocular pressure"

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Wang, Ningli, ed. Intraocular and Intracranial Pressure Gradient in Glaucoma. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2137-5.

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Principles and applications of intraocular gas. Boston: Butterworth-Heinemann, 1998.

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Whiteside, Julia Arlene. The effects of a phosphodiesterase inhibitor on intraocular pressure and ciliary process cyclic nucleotide levels in rabbits. [New Haven: s.n.], 1986.

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International, Symposium on Glaucoma Ocular Bloodflow and Drug Treatment (1990 Seville Spain). International Symposium on Glaucoma, Ocular Bloodflow, and Drug Treatment. Baltimore: Williams & Wilkins, 1992.

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Laine, Krista. Intraocular pressure lowering activities of endogenous cannabinoids, and their uptake and enzyme hydrolysis inhibitors in normotensive rabbits. Kuopio: University of Kuopio, 2004.

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Alward, Wallace L. M. Glaucoma: The requisites in ophthalmology. St. Louis: Mosby, 2000.

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Alward, Wallace L. M. Glaucoma. St. Louis: Mosby, 2000.

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A, Netland Peter, and American Academy of Ophthalmology, eds. Glaucoma medical therapy: Principles and management. 2nd ed. New York: Oxford University Press In cooperation with the American Academy of Ophthalmology, 2007.

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1950-, Allen Robert C., and Netland Peter A, eds. Glaucoma medical therapy: Principles and management. [San Francisco, Calif.]: The Foundation of the American Academy of Ophthalmology, 1999.

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Glaucoma therapy: Effective pharmacological approaches. Seattle: Hogrefe & Huber Publishers, 1996.

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Book chapters on the topic "Intraocular pressure"

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Giangiacomo, Annette. "Intraocular Pressure." In Encyclopedia of Ophthalmology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-35951-4_97-2.

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Mertz, Beat P. "Intraocular Pressure." In Drug Discovery and Evaluation: Pharmacological Assays, 3749–52. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-05392-9_85.

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Giangiacomo, Annette. "Intraocular Pressure." In Encyclopedia of Ophthalmology, 952–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-540-69000-9_97.

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Mertz, Beat P. "Intraocular Pressure." In Drug Discovery and Evaluation: Pharmacological Assays, 1–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27728-3_85-1.

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S, Ramyashri, Aparna Rao, and Sardar M. Khan. "Intraocular Pressure." In Ophthalmic Diagnostics, 201–11. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-0138-4_17.

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Yucel, Yeni H., and Neeru Gupta. "Intraocular Pressure Considerations." In Spaceflight and the Central Nervous System, 87–105. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-18440-6_7.

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Kulkarni, Avinash, Usman Sarodia, and Keith Barton. "Uveitis and Elevated Intraocular Pressure." In Intraocular Inflammation, 681–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-540-75387-2_53.

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Green, Keith. "Marihuana and Intraocular Pressure." In Marihuana and Medicine, 581–89. Totowa, NJ: Humana Press, 1999. http://dx.doi.org/10.1007/978-1-59259-710-9_57.

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Sampaolesi, Roberto, Juan Roberto Sampaolesi, and Jorge Zárate. "Intraocular Pressure Measurement: Tonometry." In The Glaucomas, 101–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-35500-4_7.

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Huang, Alex S., Lilit Minasyan, and Robert N. Weinreb. "Glaucoma-Intraocular Pressure Reduction." In Handbook of Experimental Pharmacology, 181–207. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/164_2016_24.

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Conference papers on the topic "Intraocular pressure"

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Rendon-Nava, A., and L. Nino-de-Rivera-y-O. "Intraocular Pressure Sensor Design." In 2006 3rd International Conference on Electrical and Electronics Engineering. IEEE, 2006. http://dx.doi.org/10.1109/iceee.2006.251870.

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Moorthi, M., H. S. Dhanush, A. Ashok, Sathish Kumar S, Vanitha Lakshmi M, Chee Yong Lau, and Alexander C.H.C. "Intraocular Pressure Monitoring Using IoT." In 2024 Second International Conference on Emerging Trends in Information Technology and Engineering (ICETITE). IEEE, 2024. http://dx.doi.org/10.1109/ic-etite58242.2024.10493605.

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Bukhari, Syed Ali Raza, Tanzila Afrin, Claire Floras, and Yongjun Lai. "Contact Lens-Based Intraocular Pressure Sensor." In IECB 2023. Basel Switzerland: MDPI, 2023. http://dx.doi.org/10.3390/iecb2023-14577.

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Chen, Andrew, Arjun Virk, Zachery B. Harris, Azin Abazari, Robert Honkanen, and M. Hassan Arbab. "Noninvasive THz Measurement of Intraocular Pressure." In CLEO: Science and Innovations. Washington, D.C.: OSA, 2021. http://dx.doi.org/10.1364/cleo_si.2021.sw4f.7.

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Rendon-Nava, A., L. Nino-de-Rivera-y-O, V. Ponomaryov, M. Cuz Irisson, and R. Vazquez M. "Intraocular pressure system inside vitreous humor." In 2008 International Conference on Mathematical Methods in Electromagnetic Theory (MEET). IEEE, 2008. http://dx.doi.org/10.1109/mmet.2008.4581013.

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Joos, Karen M. "Importance of intraocular pressure in glaucoma." In BiOS '99 International Biomedical Optics Symposium, edited by Pascal O. Rol, Karen M. Joos, Fabrice Manns, Bruce E. Stuck, and Michael Belkin. SPIE, 1999. http://dx.doi.org/10.1117/12.350568.

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Parel, Jean-Marie A., and Isabelle Riss. "What is the true intraocular pressure?" In BiOS '99 International Biomedical Optics Symposium, edited by Pascal O. Rol, Karen M. Joos, Fabrice Manns, Bruce E. Stuck, and Michael Belkin. SPIE, 1999. http://dx.doi.org/10.1117/12.350573.

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Manzo, Maurizio, and Omar Cavazos. "A Wireless Photonic Intraocular Pressure Sensor." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-70740.

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In this paper, we propose analytical and numerical experiments to investigate the feasibility of a wireless photonic sensor for measuring the intraocular pressure (IOP). The sensing element is a polymeric cavity embedded into a thin layer of biocompatible material integrated to a soft contact lens. The sensor concept is based on the morphology dependent resonance (MDR) phenomenon. Changes in the eye pressure perturb the micro-cavity morphology, leading to a shift in the optical modes. The IOP is measured by monitoring the shift of optical resonances. The sensor-light coupling is made through the evanescent field by using an optical prism. Therefore, the sensor can be powered and monitored wirelessly by using frustrated total internal reflection (FTIR) of a polymeric dielectric cavity. Usually, micro-optical cavities exhibit a very high quality factor Q; thus, sensors based on MDR phenomenon exhibit high resolution. Therefore, by recording tiny variations of IOP is possible to gain more knowledge about the start, comportment, and evolution of glaucoma disease.
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Po-Jui Chen, Damien C. Rodger, Saloomeh Saati, Mark S. Humayun, and Yu-Chong Tai. "Implantable parylene-based wireless intraocular pressure sensor." In 2008 IEEE 21st International Conference on Micro Electro Mechanical Systems. IEEE, 2008. http://dx.doi.org/10.1109/memsys.2008.4443592.

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Chen, Po-Jui, Saloomeh Saati, Rohit Varma, Mark S. Humayun, and Yu-Chong Tai. "Implantable Flexible-Coiled Wireless Intraocular Pressure Sensor." In 2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2009. http://dx.doi.org/10.1109/memsys.2009.4805364.

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Reports on the topic "Intraocular pressure"

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Chen, jiaqi, zheyu Bao, and xiang Li. The influence of different psychotherapy on intraocular pressure. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2023. http://dx.doi.org/10.37766/inplasy2023.8.0118.

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Li, Yinghao, Shuoqi Li, Yongqi Wang, Jianming Zhou, Jing Yang, and Jiayuan Ma. Effects of Isometric Resistance Exercise of Lower Limbs on Intraocular Pressure and Ocular Perfusion Pressure of Healthy Adults. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2021. http://dx.doi.org/10.37766/inplasy2021.1.0073.

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Almasri, Malaz, Amjad Ghareeb, Abdulrahman Ismaiel, Daniel-Corneliu Leucuta, and Simona Delia Nicoara. The role of Nepafenac in the prevention of macular swelling and its repercussions on visual outcome after cataract surgery - A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0004.

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Review question / Objective: P – diabetic and non-diabetic patients undergoing phacoemulsification without macular edema; I – Nepafenac 0.1% or Nepafenac 0.3% in addition to topical steroids; C – topical steroids alone; O – Mean Differences of Foveal thickness (FT), total macular volume (TMV), best corrected visual acuity (BCVA), and intraocular pressure (IOP); S – Randomized controlled trials (RCTs). Condition being studied: Macular swelling or macular edema after cataract surgery when uncontrolled may compromise the blood-ocular barrier and allow inflammatory cells and cytokines to enter the aqueous humor, resulting in discomfort for the patient, a slower rate of recovery, subpar visual results, and even more complications like the development of synechiae, increased IOP, macular edema (ME), corneal edema, and so forth.
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