Academic literature on the topic 'Intra-route Facilities'

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Journal articles on the topic "Intra-route Facilities"

1

Schiffer, Maximilian, Michael Schneider, and Gilbert Laporte. "Designing sustainable mid-haul logistics networks with intra-route multi-resource facilities." European Journal of Operational Research 265, no. 2 (March 2018): 517–32. http://dx.doi.org/10.1016/j.ejor.2017.07.067.

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Schiffer, Maximilian, and Grit Walther. "An Adaptive Large Neighborhood Search for the Location-routing Problem with Intra-route Facilities." Transportation Science 52, no. 2 (March 2018): 331–52. http://dx.doi.org/10.1287/trsc.2017.0746.

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3

Juta, Eshetu Mathewos. "RESOURCE SUPPLY AN ACCESSIBILITY OF PUBLIC TRANSPORTATION FACILITIES." YMER Digital 20, no. 12 (December 20, 2021): 446–55. http://dx.doi.org/10.37896/ymer20.12/42.

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The term “urban mass transit” generally refers to scheduled intra-city service on a fixed route in shared vehicles. Public transportation is an important contributing factor to urban sustainability. Effective transportation networks that incorporate public transit livable by easing commute and transportation needs and increasing accessibility. To assess public transportation accessibility in metropolitan networks, two indices are used: the supply level of urban public transportation facilities resource and the public transportation-private automobile traveling time ratio. As the research in the Wolaita sodo town region and the assessment system, an evaluation technique for urban public transportation facility resource supply is developed based on accessibility. Accessibility is a representative indicator for evaluating the supply of bus system. Traditional studies have evaluated the accessibility from different aspects. Considering the interaction among land use, bus timetable arrangement and individual factors, a more holistic accessibility measurement is proposed to combine static and dynamic characteristics from multisource traffic data. The objective is to highlight the main lessons learned and identify knowledge gaps to guide the design and evaluation of future transport investments. Moreover, studies looking at ways to improve the operational efficiency of systems and those seeking to promote behavioral changes in transport users offer great potential to generate learning that is useful for the public and private actors involved.
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4

Theeraviriya, Chalermchat, Worapot Sirirak, and Natthanan Praseeratasang. "Location and Routing Planning Considering Electric Vehicles with Restricted Distance in Agriculture." World Electric Vehicle Journal 11, no. 4 (September 30, 2020): 61. http://dx.doi.org/10.3390/wevj11040061.

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Electric vehicles (EVs) are anticipated to play a critical role in the green transportation of the future. Logistics companies have started several projects operating with EVs in road transportation. However, routing decisions for EVs must take limited driving ranges into account. Previous related research on electric vehicle location routing problems (EVLRP) has investigated intra route facilities that support the energy supply network. Contrarily, this paper studies a new type of EVLRP with a restricted distance, where EVs are used for route planning in reverse flow logistics. The model is formulated from a real case problem in agriculture that combines both locating multiple depots and determining routing paths with a limited distance constraint. An adaptive large neighborhood search (ALNS) algorithm has been extended into four combinations and is proposed here for solving the problem. The computational results indicate that the ALNS algorithm can obtain quality solutions in short processing time when compared with software using exact methods. Furthermore, the proposed ALNS algorithm is applied to a case study problem to provide suitable locations and vehicle routes with a minimized total cost.
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Cohen, Michael R. "Sometimes Things Get Lost in Translation New Color Code for 25 Gauge Safety Needles may Lead to Confusion and Errors New Tools that Address Pharmacy Issues Related to Patient Safety Intra-arterial Lines Can Unwittingly Furnish a Route for Medications Intended for IV Administration." Hospital Pharmacy 38, no. 5 (May 2003): 412–15. http://dx.doi.org/10.1177/001857870303800508.

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These medication errors have occurred in health care facilities at least once. They will happen again—perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided. You should consider publishing accounts of errors in your newsletters and/or presenting them in your inservice training programs. Your assistance is required to continue this feature. The reports described here were received through the USP Medication Errors Reporting Program, which is presented in cooperation with the Institute for Safe Medication Practices. If you have encountered medication errors and would like to report them, you may call USP toll-free, 24 hours a day, at 800–233–7767 (800–23-ERROR). Any reports published by ISMP will be anonymous. Comments are also invited; the writers' names will be published if desired. ISMP may be contacted at the address shown below.
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6

Wilcox, Susan R., Mark S. Saia, Heather Waden, Susan J. McGahn, Michael Frakes, Suzanne K. Wedel, and Jeremy B. Richards. "On-scene Times for Inter-facility Transport of Patients with Hypoxemic Respiratory Failure." Prehospital and Disaster Medicine 31, no. 3 (March 28, 2016): 267–71. http://dx.doi.org/10.1017/s1049023x16000315.

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AbstractIntroductionInter-facility transport of critically ill patients is associated with a high risk of adverse events, and critical care transport (CCT) teams may spend considerable time at sending institutions preparing patients for transport. The effect of mode of transport and distance to be traveled on on-scene times (OSTs) has not been well-described.ProblemQuantification of the time required to package patients and complete CCTs based on mode of transport and distance between facilities is important for hospitals and CCT teams to allocate resources effectively.MethodsThis is a retrospective review of OSTs and transport times for patients with hypoxemic respiratory failure transported from October 2009 through December 2012 from sending hospitals to three tertiary care hospitals. Differences among the OSTs and transport times based on the mode of transport (ground, rotor wing, or fixed wing), distance traveled, and intra-hospital pick-up location (emergency department [ED] vs intensive care unit [ICU]) were assessed. Correlations between OSTs and transport times were performed based on mode of transport and distance traveled.ResultsTwo hundred thirty-nine charts were identified for review. Mean OST was 42.2 (SD=18.8) minutes, and mean transport time was 35.7 (SD=19.5) minutes. On-scene time was greater than en route time for 147 patients and greater than total trip time for 91. Mean transport distance was 42.2 (SD=35.1) miles. There were no differences in the OST based on mode of transport; however, total transport time was significantly shorter for rotor versus ground, (39.9 [SD=19.9] minutes vs 54.2 [SD=24.7] minutes; P <.001) and for rotor versus fixed wing (84.3 [SD=34.2] minutes; P=0.02). On-scene time in the ED was significantly shorter than the ICU (33.5 [SD=15.7] minutes vs 45.2 [SD=18.8] minutes; P <.001). For all patients, regardless of mode of transportation, there was no correlation between OST and total miles travelled; although, there was a significant correlation between the time en route and distance, as well as total trip time and distance.ConclusionsIn this cohort of critically ill patients with hypoxemic respiratory failure, OST was over 40 minutes and was often longer than the total trip time. On-scene time did not correlate with mode of transport or distance traveled. These data can assist in planning inter-facility transports for both the sending and receiving hospitals, as well as CCT services.WilcoxSR, SaiaMS, WadenH, McGahnSJ, FrakesM, WedelSK, RichardsJB. On-scene times for inter-facility transport of patients with hypoxemic respiratory failure. Prehosp Disaster Med. 2016;31(3):267–271.
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Tan, Ting Wan, Han Ling Tan, Man Na Chang, Wen Shu Lin, and Chih Ming Chang. "Minimize Risk of Intra-Hospital Acquired Transmission to Confront Pandemic COVID-19 in Taiwan." International Journal of Pharmaceutical Sciences and Medicine 6, no. 2 (February 28, 2021): 44–47. http://dx.doi.org/10.47760/ijpsm.2021.v06i02.005.

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Since December 2019, the COVID-19 confirmed case number has increased rapidly in China. Subsequently has spread globally. Since late January 2020, Taiwan CDC and government have took measures early and quick response to Covid-19, take action to develop strategies to manage epidemic crisis and community spread in early stage. Taiwan has aware importance of design of isolation route from emergency department, outpatient, intensive care unit, ordinary ward and isolation rooms in health care facilities. For yearly hospital evaluation has been assessed elements that related functional capacity of hospital safety, which aims to examine the level of preparedness of hospital staffs for major emergencies or disaster.
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8

Zawadzki, Michal, Jerzy Walecki, Boguslaw Kostkiewicz, Kacper Kostyra, Monica Smith Pearl, Meiyappan Solaiyappan, Piotr Walczak, and Miroslaw Janowski. "Republished: Real-time MRI guidance for intra-arterial drug delivery in a patient with a brain tumor: technical note." Journal of NeuroInterventional Surgery 11, no. 8 (May 23, 2019): e3-e3. http://dx.doi.org/10.1136/neurintsurg-2018-014469.rep.

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Patients suffering from malignant brain tumors are burdened with a grim prognosis. The blood brain barrier is considered a primary obstacle in therapeutic drug delivery to the brain. Intra-arterial (IA) delivery of therapeutic agents following osmotic BBB opening has been attempted for years, but high variability has limited its widespread implementation. It has been recently shown in animal studies that MRI is superior to X-ray for guiding IA infusions, as it allows direct visualization of the brain parenchyma perfused and facilitates predictable drug targeting. Moreover, PET imaging has revealed that IA, not intravenous, delivery of bevacizumab results in brain accumulation, providing strong rationale for utilizing the IA route. Here, we present our experience in a patient with recurrent butterfly glioblastoma enrolled in first-in-man MRI-guided neurointervention for targeted IA drug delivery.
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9

Zawadzki, Michal, Jerzy Walecki, Boguslaw Kostkiewicz, Kacper Kostyra, Monica Smith Pearl, Meiyappan Solaiyappan, Piotr Walczak, and Miroslaw Janowski. "Real-time MRI guidance for intra-arterial drug delivery in a patient with a brain tumor: technical note." BMJ Case Reports 12, no. 1 (January 2019): bcr—2018–014469. http://dx.doi.org/10.1136/bcr-2018-014469.

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Patients with malignant brain tumors have a poor prognosis. The blood–brain barrier (BBB) is considered a primary obstacle in therapeutic drug delivery to the brain. Intra-arterial (IA) delivery of therapeutic agents following osmotic BBB opening has been attempted for years, but high variability has limited its widespread implementation. It has recently been shown in animal studies that MRI is superior to X-ray for guiding IA infusions, as it allows direct visualization of the brain parenchyma supplied by the catheter and facilitates predictable drug targeting. Moreover, PET imaging has shown that IA rather than intravenous delivery of bevacizumab results in accumulation in the brain, providing a strong rationale for using the IA route. We present a patient with recurrent butterfly glioblastoma enrolled in a first-in-man MRI-guided neurointervention for targeted IA drug delivery.
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10

Monostory, Katalin, Andrea Nagy, Katalin Tóth, Tamás Bűdi, Ádám Kiss, Máté Déri, and Gábor Csukly. "Relevance of CYP2C9 Function in Valproate Therapy." Current Neuropharmacology 17, no. 1 (December 5, 2018): 99–106. http://dx.doi.org/10.2174/1570159x15666171109143654.

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Background: Genetic polymorphisms of drug metabolizing enzymes can substantially modify the pharmacokinetics of a drug and eventually its efficacy or toxicity; however, inferring a patient’s drug metabolizing capacity merely from his or her genotype can lead to false prediction. Non-genetic host factors (age, sex, disease states) and environmental factors (nutrition, comedication) can transiently alter the enzyme expression and activities resulting in genotypephenotype mismatch. Although valproic acid is a well-tolerated anticonvulsant, pediatric patients are particularly vulnerable to valproate injury that can be partly attributed to the age-related differences in metabolic pathways. </P><P> Methods: CYP2C9 mediated oxidation of valproate, which is the minor metabolic pathway in adults, appears to become the principal route in children. Genetic and non-genetic variations in CYP2C9 activity can result in significant inter- and intra-individual differences in valproate pharmacokinetics and valproate induced adverse reactions. </P><P> Results: The loss-of-function alleles, CYP2C9*2 or CYP2C9*3, display significant reduction in valproate metabolism in children; furthermore, low CYP2C9 expression in patients with CYP2C9*1/*1 genotype also leads to a decrease in valproate metabolizing capacity. Due to phenoconversion, the homozygous wild genotype, expected to be translated to CYP2C9 enzyme with normal activity, is transiently switched into poor (or extensive) metabolizer phenotype. Conclusion: Novel strategy for valproate therapy adjusted to CYP2C9-status (CYP2C9 genotype and CYP2C9 expression) is strongly recommended in childhood. The early knowledge of pediatric patients’ CYP2C9-status facilitates the optimization of valproate dosing which contributes to the avoidance of misdosing induced adverse reactions, such as abnormal blood levels of ammonia and alkaline phosphatase, and improves the safety of children’s anticonvulsant therapy.
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