Dissertations / Theses on the topic 'Intervention approach'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Intervention approach.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Williams, A. Lynn. "A Multiple Oppositions Intervention Approach." Digital Commons @ East Tennessee State University, 2003. https://www.amzn.com/0769302564/.
Chumley, Steven L. "The Best Approach to Crisis Intervention." Thesis, Monterey, California. Naval Postgraduate School, 2012. http://hdl.handle.net/10945/17344.
First responders protect and serve. They maintain order, prevent chaos, and keep this country safe and secure. Many of the freedoms enjoyed today are the result of U.S. first responders protecting and caring for U.S. citizens. Whether it is a terrorists attack, a criminal victimizing a citizen, or a natural disaster, first responders will be among the first on the scene to deal with the crisis. For this reason, their role in homeland security is so critical. Traumatic stress experienced by first responders may impact their ability to function and handle the next critical incident, as well as obstruct public safety agencies in maintaining a robust and resilient workforce. As a result, leaders of first responder organizations need methods to recognize the different levels of stress their employees are experiencing and identify ways they can support their officers and minimize long-term effects of stress, including absenteeism, early resignation/retirement, depression, post-traumatic stress, substance abuse, and suicide. Critical Incident Stress Management (CISM) is the standard clinical practice most widely utilized by public safety agencies in crisis interventions. CISM is designed to mitigate stress and Post Traumatic Stress Disorder (PTSD). Another technique to help the traumatized, now emerging as a preferred response in crisis interventions, is Psychological First Aid (PFA). The empirical evidence is examined comparing CISM and PFA in an attempt to determine the best care for first responders. Another valuable tool examined, and sometimes overlooked as a crisis intervention tool, is the role of trained chaplains in disaster care. The author has responded to numerous traumatic incidents and witnessed firsthand the effects trauma has on first responders. As a result of witnessing the lack of care CISM provides, he was inspired to research and find the best approach to crisis interventions. PFA and trained chaplains may be the answer; however, the author also desires that this paper inspire and challenge other agencies to invest, conduct further research, and ultimately, find the best approach to crisis interventions.
Dickinson, Wendy Lynn. "Increasing coping resources an experimental intervention approach /." unrestricted, 2006. http://etd.gsu.edu/theses/available/etd-09252006-095205/.
Title from title screen. Jeffery S. Ashby, committee chair; Kenneth B. Matheny, Greg Brack, T. Chris Oshima,committee members. Electronic text (86 p.) : digital PDF file. Description based on contents viewed June 14, 2007. Includes bibliographical references (p. 68-75).
Dickinson, Wendy Lynn. "Increasing Coping Resources: An Experimental Intervention Approach." Digital Archive @ GSU, 2007. http://digitalarchive.gsu.edu/cps_diss/6.
Williams, A. Lynn, and J. Kalbfleisch. "A Multiple Opposition Approach to Phonological Intervention." Digital Commons @ East Tennessee State University, 1999. https://dc.etsu.edu/etsu-works/2101.
Williams, A. Lynn. "Phonological Intervention Using a Multiple Opposition Approach." Digital Commons @ East Tennessee State University, 1996. https://dc.etsu.edu/etsu-works/2029.
Williams, A. Lynn, and John Kalbfleisch. "Phonological Intervention using a Multiple Opposition Approach." Digital Commons @ East Tennessee State University, 2001. https://dc.etsu.edu/etsu-works/2095.
Williams, A. Lynn. "A Phonological Approach to Assessment and Intervention." Digital Commons @ East Tennessee State University, 1998. https://dc.etsu.edu/etsu-works/2027.
Russell, Anthony Charles. "A workshop intervention approach to nursing stress management." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1996. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/MQ33447.pdf.
Williams, A. Lynn. "A Systemic Approach to Phonological Assessment and Intervention." Digital Commons @ East Tennessee State University, 1999. https://dc.etsu.edu/etsu-works/2026.
Williams, A. Lynn. "From Assessment to Intervention: A Systemic Phonological Approach." Digital Commons @ East Tennessee State University, 1997. https://dc.etsu.edu/etsu-works/2108.
Hall, Jessica Faye. "The development of an intervention for carers of stroke survivors using an Intervention Mapping approach." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/20345/.
Chater, Angel Marie. "Children's health perception and health behaviour : an intervention approach." Thesis, University of Roehampton, 2006. https://pure.roehampton.ac.uk/portal/en/studentthesis/children’s-health-perception-and-health-behaviour(a06c6553-ed09-4a4c-acbe-b30c865d9292).html.
Bansell, Marianne. "Smartwatches in the elderly care - a design intervention approach." Thesis, Malmö universitet, Fakulteten för kultur och samhälle (KS), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-21694.
Bradley, William Worth. "Therapeutic intervention with suicidal adolescents: A problem-solving approach." W&M ScholarWorks, 1986. https://scholarworks.wm.edu/etd/1539618886.
Du, Plessis Sandra. "Multilingual preschool learners: a collaborative approach to communication intervention." Thesis, University of Pretoria, 2006. http://hdl.handle.net/2263/28280.
Thesis (DPhil (Communication Pathology))--University of Pretoria, 2007.
Speech-Language Pathology and Audiology
Unrestricted
Sanni, Kemi Funlayo. "An Evidence-Based Approach to Percutaneous Coronary Intervention Access." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5262.
Tarrant, Robert Gerard. "Early childhood intervention in rural Newfoundland, a community-based approach." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0021/MQ54964.pdf.
Empelen, Pepijn van. "AIDS prevention among Dutch drug users an intervention mapping approach /." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 2001. http://arno.unimaas.nl/show.cgi?fid=5986.
Voerman, Gerritje Evelien. "Musculoskeletal neck-shoulder pain a new ambulant myofeedback intervention approach /." Enschede : University of Twente [Host], 2007. http://doc.utwente.nl/57841.
Tilbury, Emma. "The psychodynamic approach to observing organisations : towards a psychosocial intervention." Thesis, University of Leicester, 2012. http://hdl.handle.net/2381/27573.
Solomonides, Ian Paul. "Learning intervention and the approach to study of engineering undergraduates." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308312.
Williams, A. Lynn. "Multiple Oppositions: Theoretical Foundations for an Alternative Contrastive Intervention Approach." Digital Commons @ East Tennessee State University, 2000. https://dc.etsu.edu/etsu-works/2007.
Hirsch, Jameson K., L. Wingate, C. Bryan, Peter C. Britton, C. Genest, and K. Rasmussen. "A Positive Psychological Approach to Suicide Research, Prevention and Intervention." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/601.
Ryan, Jill. "The design of an intervention to reduce violence in the family: A family–centred approach." University of the Western Cape, 2018. http://hdl.handle.net/11394/6960.
Violence occurs in different environments, however, it is often found in the family with family members being the perpetrators. Family violence, as an integrative concept, is defined by few researchers or theorists, let alone conceptualised as a theoretical grounding for family-centred interventions aimed at violence in the home. However, family members are all affected in the act of any violence in the family, thus any intervention should include the whole family. A family-centred approach focuses on all family members to be included in the intervention and is acknowledged as the best method when trying to create an intervention for family violence. Thus, the aim of this study was to design an intervention programme for families experiencing family violence in order to reduce violence in the family. To create such a programme, intervention mapping was the chosen design for this study. Intervention mapping has five steps, 1.) Specify the programme’s goals into proximal programme objectives. In this stage, needs are identified; 2.) Selection of theoretical and practical strategies; 3.) Design the programme, 4.) Implementation of the programme, and 5.) Focus on anticipating process and effect evaluation. However, this study only focused on the first 3 steps of intervention development, namely, Phase I, a family violence needs assessment done to identify the problem, Phase II entailed a review done to determine appropriate theoretical and practical approaches for the intervention regarding family violence, and lastly, Phase III had been a Delphi study which aided in the design and development of the intervention. This study showed promising results with proven long-term positive effects in implementing a family-centred approach, and when coupled with a collaborative network of support services, political will, and community support, and has the ability to ensure continuity of care and improved functioning for families experiencing violence in the home.
Bruns, Claudia. "A usage-based approach to language processing and intervention in aphasia." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10062404/.
Golan, Guy D. "Countering violent extremism| A whole community approach to prevention and intervention." Thesis, California State University, Long Beach, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10065201.
The United States national strategy for Countering Violent Extremism is broadly written and currently does not provide the framework necessary to combat homegrown violent extremism and the foreign fighter phenomenon. The threat of foreign terrorist organizations targeting the United States through a 9/11-style attack has become overshadowed by the threat of homegrown violent extremists and lone-wolf attacks. The purpose of this thesis is to gain a comprehensive insight into how intervention is used within the context of a counter-terrorism preventative strategy. How can intervention be used to disengage radicalizing individuals whose expression of extremist ideology involves committing violent acts? Furthermore, it is anticipated that the most appropriate methods for applying such an intervention program, in the pre-criminal space, can be most successful through interagency collaboration and a Whole Community approach. Such a system leverages partnerships between local, state, and federal government agencies, nongovernmental organizations, and community-driven initiatives. This paper analyzes specific case studies of socio-political landscapes, individuals who have radicalized to violent extremism, and intervention programs from Denmark, Canada, the United Kingdom, and the United States. The results of the analysis provide recommendations for implementing a nation-wide intervention program in the United States.
Birleson, Angela. "Promoting employment in young-onset Parkinson's disease : a staged intervention approach." Thesis, Northumbria University, 2010. http://nrl.northumbria.ac.uk/7256/.
Woienski, Richard T. "Suicide an integrated pastoral approach /." Theological Research Exchange Network (TREN), 1997. http://www.tren.com.
Rinaldi, Roberto L. "A Developmental Intervention Science Outreach Research Approach to Promoting Positive Youth Development." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/342.
Dempton, Jennifer L. "Genetic intervention as a lifestyle approach an analysis of disease and treatment." Honors in the Major Thesis, University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/368.
B.S.N.
Bachelors
Nursing
Nursing
McKinley, Lauren E. "Increasing Teachers' Intervention Adherence through a Multi-Tiered System of Support Approach." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1479817366518158.
Bates, Sarah H. "Investigation of potential intervention targets to improve insulin action: a therapeutic approach." Thesis, Aston University, 1999. http://publications.aston.ac.uk/10980/.
Livaic, Zelko F., of Western Sydney Nepean University, and Faculty of Business. "Privatisation and market structure : a game theoretic approach." THESIS_FB_XXX_Livaic_Z.xml, 2000. http://handle.uws.edu.au:8081/1959.7/348.
Doctor of Philosophy (PhD)
Graham, Fiona. "Development and evaluation of a point-of-choice intervention to increase healthy and environmentally friendly food consumption : an intervention mapping approach." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/22330/.
Shin, Lynna Betty. "Improving the Learning Approach of College Freshmen and Future Teachers Through Curricular Intervention." Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1493.pdf.
Clow, Lisa Ann. "Yoga as a Women’s Population Health Intervention." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7621.
Taylor, David. "Use of the Transdisciplinary Teaming Approach for Early Intervention Service Delivery in Kentucky." TopSCHOLAR®, 1995. http://digitalcommons.wku.edu/theses/889.
Ranellucci, John. "Unmasking the academic achievement potential of mastery-approach goals: a mastery-focused intervention." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121332.
Les effets de trois interventions développées afin de stimuler la réussite scolaire chez les élèves orientés vers la maîtrise ont été évalués quant à trois variables qui sont considérées comme étant responsable de cet effet, notamment, les intérêts par rapport à l'étude, la difficulté perçue de la tâche, et la désirabilité sociale. Les étudiants de premier cycle (N =177) ont complété les mesures d'auto-évaluation pertinentes au début et à la fin du semestre. À la suite du premier questionnaire, les participants ont été assigné au hasard à l'une des trois conditions d'intervention (les intérêts par rapport à l'étude, la difficulté perçue de la tâche, et la désirabilité sociale) ou un groupe control. Les résultats de régression multiple et successive avec variable muette ont démontré que la seule variable à toujours être prédite par les conditions d'intervention est les intérêts par rapport à l'étude, avec ces effets étant modéré par l'accomplissement académique préalable et les buts de maîtrise.
Hankinson, Colin. "An evaluation of the learning styles approach to education : a minimal intervention strategy." Thesis, University of Manchester, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488159.
Watt, P. A. "Topics in the analysis of government expenditure and intervention : a public choice approach." Thesis, University of York, 1988. http://etheses.whiterose.ac.uk/10782/.
Hoar, Robyn. "Strategic approach to psychotherapeutic intervention with male institutionalized white adolescents to control absconding." Master's thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/15888.
Using a systems theoretical orientation the objective of this study was to implement a strategic approach for psychotherapeutic intervention with six male institutionalized white adolescents at a local custodial school. It was hypothesized that a strategic approach would control absconding for the duration of the investigation. Surveys of the literature were undertaken to provide the background to psychotherapeutic intervention with adolescents in custodial institutions, strategic psychotherapy and absconding. Absconding was selected as the condition for evaluating the interventions because it was an unambiguous indicator of school-based recidivism, viz., the adolescent was either on the property or he was not. The study was structured as a design-and-demonstrate investigation. Audiotape recordings were made during the sessions. Transcriptions of characteristic procedures and sequences of the strategic approach to psychotherapeutic intervention were presented, inter alia, paradoxes, reframing, metaphors, rituals, the declaration of therapeutic impotence. Evaluation of the interventions was based on follow-up interviews with the subjects and a qualitative analysis of risk of absconding aver the course of the intervention process. At the end of the investigation there was some evidence which suggested that five out of the six subjects were not as committed to absconding as they had claimed to be at the beginning of the study. The design of the study did not allow for the conclusion that the strategic approach for controlling absconding was of greater merit than any other form of intervention or no intervention at all. It was noted, however, that twelve of the eighteen potential subjects for the study indicated that they would abscond as soon as the opportunity arose. Therefore it was recommended that the issue of absconding be given priority in therapy on the admission of each new pupil. Given a strategic approach to addressing the issue of absconding in therapy, attention was drawn to a major aim of this type of intervention, viz., to generate a sense of personal autonomy. Hence a further recommendation was that once a pupil had made a commitment not to abscond, his sense of autonomy would need to be supported by an expeditious transfer to one of the more open hostels.
Pinijphon, Ponsopa. "An ICM approach to the assessment of a medical ethics intervention in Thailand." Thesis, [Tuscaloosa, Ala. : University of Alabama Libraries], 2009. http://purl.lib.ua.edu/96.
Campbell, Catherine. "'Little Steps' in Early Intervention with Sexually Abused Children: A Child-Centric Approach." Thesis, Campbell, Catherine (2010) 'Little Steps' in Early Intervention with Sexually Abused Children: A Child-Centric Approach. PhD thesis, Murdoch University, 2010. https://researchrepository.murdoch.edu.au/id/eprint/3425/.
Lal, Shubhangi S. "Designing Interventions for Cyber-bullying: A Design Thinking Approach." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1627666831641494.
Vogel, Kai. "Unveiling the Burqa Ban: An Examination of Humanitarian Intervention in Martha Nussbaum's Capabilities Approach." Scholarship @ Claremont, 2019. https://scholarship.claremont.edu/cmc_theses/2007.
Arnautovska, Urska. "Physical Activity in Older Adults: Influences and Intervention Strategies using an Integrative Theory-based Approach." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/366098.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Applied Psychology
Griffith Health
Full Text
Longo, Francesca. "Two-Generation Approach to Improving Emotional and Behavioral Regulation:." Thesis, Boston College, 2017. http://hdl.handle.net/2345/bc-ir:107319.
Increasing evidence indicates that exposure to poverty in early childhood may undermine neural growth that is critical to developing executive functions (EF) and, in turn, emotional and behavioral regulation (Blair et al. 2011; Kim et al., 2013; Raver et al., 2013). There is, however, also increasing evidence indicating that high-quality Early Childhood Education (ECE) (a) buffers children from risks associated with early exposure to poverty and (b) supports healthy socio-emotional development (Bierman et al., 2008; Raver, 2002; Yoshikawa et al., 2013). One line of this intervention work has focused on two-generation programs that pair high-quality ECE with supports for parents that are designed to improve parenting and the home environment. Although evidence on two-generation programs is mixed (Grindal et al., 2016; Neville et al., 2013), it is clear that much of the risk of poverty is relayed to children through their homes, and parenting is among the most critical influences on child emotional and behavioral self-regulation in infancy and early childhood (Bradley & Corwyn, 2004; Calkins & Johnson, 1998; Calkins et al., 1998). The present study builds on existing theoretical and empirical prior work indicating that children’s EF skills are important precursors to emotional and behavioral regulation that may be best promoted when addressed in both classroom and home contexts. Specifically, the present study uses a randomized design to evaluate the effects of classroom-based activities that target children’s executive functioning and the value added by training parents to better support their children’s EFs. Children were evaluated pre- and post-intervention on EF skills and prosocial and adaptive problem-solving behavior. In general, few significant effects of either the child training or the added parent component were evident. These findings are discussed with special attention to the fact that fidelity of implementation of the classroom and parent trainings was low, with less than half of teachers incorporating games at least once a week and only 13 percent of parents attending the trainings. In addition, implications for future empirical work as well as policy and practice are discussed with special attention given to further inquiry into the malleability of EF
Thesis (PhD) — Boston College, 2017
Submitted to: Boston College. Lynch School of Education
Discipline: Counseling, Developmental and Educational Psychology
Toro, Quezada Edgardo Patricio. "Analysis of policy and legal frameworks, intervention models and intervention practices on commercial sexual exploitation of children in Chile : a discourse analysis approach." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31196.
González, Franquesa Alba. "Assessing metabolic plasticity in diet-induced obese mice upon lifestyle intervention. An integrative approach." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/396201.
La Diabetes Mellitus del tipus 2 (DM2) és una malaltia que es caracteritza per uns nivells elevats de glucosa i insulina circulants ocasionats per un estat de resistència a la insulina. Segons la International Diabetes Federation, el 2013 382 milions de persones van ser diagnosticades de diabetes (8.3% de la població mundial), i d’acord amb les prediccions aquesta xifra augmentarà fins els 592 milions en els pròxims 22 anys. La DM2 explica el 90% dels casos de diabetes (WHO 1999). L’obesitat és un factor de risc per la DM2 i avui en dia suposa una epidèmia: el 2014 la OMS va xifrar en 1.9 bilions la població adulta amb sobrepès i 600 milions amb obesitat. A part del cost econòmic que suposa per a la societat, la OMS va projectar que el 2013 la DM2 serà la setena causa de mort al món (Mathers & Loncar 2006). Un cop diagnosticada, la primera aproximació en l’assessorament al pacient amb DM2 o en un estat de risc consisteix en una intervenció en l’estil de vida: incrementant l’activitat física i portant a terme una dieta equilibrada i saludable. Aquest projecte té com a objectiu l’estudi i la integració de les respostes metabòliques responsables de regular l’homeostasi de la glucosa a nivell sistèmic. Avui en dia, no existeix cap treball que descrigui de forma holística els diferents processos metabòlics que regulen l’homeostasi de la glucosa en tots els teixits que juguen un paper determinant durant el desenvolupament de la DM2 associada a l’obesitat. D’aquesta manera, es pretén guanyar coneixement sobre les alteracions metabòliques que tenen lloc en un estat d’obesitat induït per una dieta rica en greixos, i així mateix valorar el grau de reversibilitat que es pot assolir mitjançant una intervenció en l’estil de vida, al que ens referim com a “plasticitat metabòlica”. Utilitzem un model animal d’obesitat i DM2 induïda per una dieta alta en greixos. Per aconseguir els objectius plantejats inicialment es realitza un estudi fenotípic i funcional a nivell sistèmic per més tard realizar una aproximació experimental més exhaustiva en cadascun dels teixits d’interès: pàncrees, teixit adipós blanc, fetge, múscul esquelètic oxidatiu i glicolític, i hipotàlem. Aquesta aproximació experimental engloba anàlisis funcionals-teixit específic, estudis d’expressió gènica, determinació del contingut proteic i les vies de senyalització, metabolòmica i RNAseq. Així mateix, s’han desenvolupat eines de biologia de sistemes que han permès calcular diferents correlacions i fer diferents tipus d’anàlisis multivariant amb tots els paràmetres estudiats. Es defineixen tres grups experimentals d’animals que concreten els estats metabòlics d’interès: grup control (Ctrl); grup patològic (HFD) (que simula la DM2 induïda per la dieta grassa durant 16 setmanes, i en què els animals tenen sobreprès i la glucosa i insulina circulants elevades en dejú); i un tercer grup que segueix una intervenció en l’estil de vida (Int) que consisteix en restricció calòrica, una modificació de la font d’àcids grassos i hidrats de carboni de la dieta, juntament amb la realització d’un programa d’exercici. El grup experimental d’obesitat induïda per una dieta grassa (grup HFD) presenta les característiques fisiològiques pròpies de l’estat patològic: sobrepès, hiperglucèmia, hiperinsulinèmia i hiperleptinèmia en dejú, augment de la massa i el volum de greix, augment del pes del teixit adipós blanc, el fetge i el pàncrees, augment dels nivells de triglicèrids en fetge i múscul oxidatiu, intolerància a la glucosa, resistència a la insulina, augment de la massa de cèl·lula beta en el pàncrees juntament amb illots hipertròfics engrandits i disfunció de la secreció d’insulina estimulada per glucosa in vivo i in vitro, i disfunció del consum d’oxigen, generació de calor i temperatura escapular. La intervenció va ser suficient per revertir gran part de les alteracions observades en el grup patològic. No obstant, encara s’observa cert grau d’irreversibilitat en determinats paràmetres estudiats: (1) alteració de la glucosa en dejú i la resposta insulínica davant d’un estímul de glucosa in vivo, (2) increment en l’àrea de cèl·lula beta pancreàtica, (3) afectació en el teixit adipós blanc epididimal amb la presència d’inflamació i infiltració de cèl·lules immunes, així com (4) disfunció mitocondrial, ja observats en l’estat patològic. Amb tot, podem concloure que l’estat patològic deixa un cert grau d’irreversibilitat metabòlica no permetent així una recuperació total del fenotip en tots els teixits estudiats, almenys, amb aquest tipus d’intervenció i aquests períodes de temps. El desenvolupament i l’aplicació d’eines de biologia de sistemes han permès estudiar el grau de reversibilitat d’una manera integrada, les correlacions entre paràmetres concrets a nivel multiorgànic, el patró d’expressió gènica de complexes descrits en una xarxa de protein-protein-interaction (PPI). Aquestes estratègies computacionals han permès identificar aquells teixits i vies metabòliques més alterades en els diferents estats estudiats.