Academic literature on the topic 'Intensity modulated radiotherapy'

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Journal articles on the topic "Intensity modulated radiotherapy"

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Leibel, Steven A., Zvi Fuks, Michael J. Zelefsky, Suzanne L. Wolden, Kenneth E. Rosenzweig, Kaled M. Alektiar, Margie A. Hunt, et al. "Intensity-Modulated Radiotherapy." Cancer Journal 8, no. 2 (March 2002): 164–76. http://dx.doi.org/10.1097/00130404-200203000-00010.

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Tomé, Wolfgang A., Sanford L. Meeks, Todd R. McNutt, John M. Buatti, Francis J. Bova, William A. Friedman, and Minesh Mehta. "Optically guided intensity modulated radiotherapy." Radiotherapy and Oncology 61, no. 1 (October 2001): 33–44. http://dx.doi.org/10.1016/s0167-8140(01)00414-5.

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Armugram, Nindra, and Krishna Kadarlab. "Toxicities and Outcome of Intensity Modulated Radiotherapy Vs 2D Conformal Radiotherapy in Head and Neck Cancers." Indian Journal of Cancer Education and Research 5, no. 2 (2017): 61–67. http://dx.doi.org/10.21088/ijcer.2321.9815.5217.2.

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Eschwège, Maurice Tubiana, Francois. "Conformal Radiotherapy and Intensity-modulated Radiotherapy: Clinical Data." Acta Oncologica 39, no. 5 (January 2000): 555–67. http://dx.doi.org/10.1080/028418600750013249.

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Śladowska, A. "Modern External Beam Radiotherapy Techniques - Intensity Modulated Radiotherapy." Acta Physica Polonica A 115, no. 2 (February 2009): 586–90. http://dx.doi.org/10.12693/aphyspola.115.586.

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Fischer-Valuck, Ben W., Yuan James Rao, and Jeff M. Michalski. "Intensity-modulated radiotherapy for prostate cancer." Translational Andrology and Urology 7, no. 3 (June 2018): 297–307. http://dx.doi.org/10.21037/tau.2017.12.16.

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Thilmann, Christoph, Daniela Schulz-Ertner, Angelika Zabel, Klaus K. Herfarth, Michael Wannenmacher, and Jürgen Debus. "Intensity-Modulated Radiotherapy of Sacral Chordoma." Acta Oncologica 41, no. 4 (January 2002): 395–99. http://dx.doi.org/10.1080/028418602760169460.

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Budgell, G. "Intensity modulated radiotherapy (IMRT)—an introduction." Radiography 8, no. 4 (November 2002): 241–49. http://dx.doi.org/10.1053/radi.2002.0390.

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Low, Daniel A. "Quality assurance of intensity-modulated radiotherapy." Seminars in Radiation Oncology 12, no. 3 (July 2002): 219–28. http://dx.doi.org/10.1053/srao.2002.33700.

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Taylor, A. "Intensity-modulated radiotherapy - what is it?" Cancer Imaging 4, no. 2 (2004): 68–73. http://dx.doi.org/10.1102/1470-7330.2004.0003.

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Dissertations / Theses on the topic "Intensity modulated radiotherapy"

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Cufflin, Rebecca Sian. "Verification of Intensity Modulated Radiotherapy." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/25873/.

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The main aim of this work was to develop accurate and efficient methods for the verification of Intensity Modulated Radiotherapy (IMRT). IMRT is an advanced form of radiotherapy demanding extensive verification procedures to ensure treatments are delivered accurately. This requires comprehensive sampling of the complex dose distributions impacting on the tumour volume and radiationsensitive ‘organs at risk’. This work has focused on the use of electronic portal imaging devices (EPIDs) for verification purposes. Modern EPIDs are composed of a scintillator and an amorphous silicon detector panel with an array of photodiodes and thin film transistors. They are primarily used to verify the patient position during treatment by capturing transmission images, but they also have the potential to be used as efficient dose verification tools of high spatial resolution. Two complementary dose verification methods have been developed. One approach involves the calculation of portal dose using Monte Carlo (MC) methods. A MC model of the linear accelerator, in combination with the EPID, enables the dose to the detector to be predicted accurately and compared directly with acquired images. An alternative approach has also been developed. This utilises a clinical treatment planning system (TPS) to calculate the dose at the detector level, and convert this to predicted EPID intensity by application of a series of derived correction factors. Additionally, there have been numerous publications in the literature detailing problems in dosimetry caused by non-uniform backscatter to the imager from the model of detector support arm used in this work. Two novel methods to correct for this issue have been developed, a MC modelling solution and a matrix-based correction. These developed methods for IMRT dose verification have been applied both prior to and during treatment. When applied to pre-treatment verification, the MC solution is accurate to the 2%, 2 mm level (an average of 96% of points passing gamma criteria of 2%, 2 mm) and the TPS based method is accurate to the 3%, 3 mm level (an average of 98% of points passing gamma criteria of 3%, 3 mm). Both verification methods achieve acceptable verification results during treatment at the 5%, 5 mm level (average gamma pass rates of 97% and 96% being achieved for the MC and TPS based solutions respectively). Furthermore, in initial clinical studies, both techniques have identified dose delivery errors due to changes in patient position or patient anatomy.
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Bär, Werner. "Optimized delivery of intensity modulated radiotherapy." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965610934.

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Khadija, Murshed. "A clinical comparison and analysis between conventional MLC based and solid compensator based IMRT treatment techniques [electronic resource] /." Toledo, Ohio : University of Toledo, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=mco1264434257.

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Thesis (M.S.)--University of Toledo, 2009.
"In partial fulfillment of the requirements for the degree of Master of Science in Biomedical Sciences." Title from title page of PDF document. Bibliography: p. 34-35.
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Seco, Joao Carlos. "Comparison of the efficacy of intensity modulated radiotherapy." Thesis, Institute of Cancer Research (University Of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398937.

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Williams, Matthew John Physics Faculty of Science UNSW. "Investigations into static multileaf collimator based intensity modulated radiotherapy." Awarded by:University of New South Wales. Physics, 2005. http://handle.unsw.edu.au/1959.4/20577.

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Intensity Modulated Radiation Therapy (IMRT) is a modern radiotherapy treatment technique used to obtain highly conformal dose distributions. The delivery of IMRT is commonly achieved through the use of a multileaf collimator (MLC). One of the hindrances at present to the widespread use of IMRT is the increased time required for its planning, delivery and verification. In this thesis one particular method of MLC based IMRT, known as Static Multileaf Collimator based IMRT (SMLC-IMRT), has been studied along with methods for improving it???s delivery efficiency. The properties of an MLC commonly used in SMLC-IMRT have been characterised. The potential ramifications of these properties on the dosimetric accuracy of the delivered IMRT field were also investigated. An Interactive Leaf Sequencing (ILS) program was developed that allowed for the manipulation and processing of intensity maps using a variety of methods. The objective of each method was to improve the delivery efficiency whilst maintaining the dosimetric quality of the IMRT treatment. The different methods investigated were collimator angle optimisation, filtration, and intensity level optimisation. The collimator was optimised by identifying the angle at which the minimum monitor unit???s (MU???s) were required when using a sliding-window delivery method. A Savitzky-Golay filter was applied to random intensity maps and suitable filtration parameters identified for filtering clinical IMRT fields, and the intensity levels were optimised based on a deviation threshold. The deviation threshold identified the acceptable level of difference tolerable between the original and modified intensity map. Several IMRT cases were investigated and the impact of each the methods on MU???s, segments and dose distribution observed. As the complexity of IMRT fields increases the dosimetric impact of the MLC properties increases. Complex SMLC-IMRT fields require longer delivery times due to the increased number of MU???s and segments. Collimator optimisation was shown to be a fast and effective means of improving delivery efficiency with negligible dosimetric change to the optimised plan. Modifying intensity maps by applying a filter and optimising the intensity levels did reduce the complexity and improve the delivery efficiency, but also required a dosimetric compromise of the optimised plan.
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Glendinning, Andrew D. "Studies of the dosimetric verification of intensity modulated radiotherapy." Thesis, University of Leicester, 2001. http://hdl.handle.net/2381/29383.

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The ability to verify absorbed dose distributions produced by intensity modulated radiotherapy (IMRT) using dynamic multileaf collimation is of great concern in the clinical application of this technique. This thesis investigates two approaches using an Elekta SL/ linear accelerator operating in dynamic mode (Elekta Oncology Systems, Crawley, UK). A novel strip ionisation chamber array, located at the beam aperture, was designed and used in conjunction with a specialised electrometer. This also recorded cumulative accelerator monitor units (MU) via an isolated interface to the accelerator. The chamber signal, recorded as a function of MU, proved suitable for collimator position verification for the case of a dynamic wedge, but was found not to be suitable for more general cases in which the leaves moved independently. A tube camera-based electronic portal imaging device (EPID) (Theraview , Cablon Medical, Leusden, The Netherlands) was investigated in a further approach to verification. This EPID has not been previously studied for dosimetry and several unreported effects associated with the video system were identified. The phosphor Gd202S:Tb, which is used as the x-ray detector, was also studied by direct measurements of luminescence using a photomultiplier tube. It was confirmed that the optical signal was independent of accelerator pulse repetition frequency, and that there was no long- lived luminescence (afterglow) following prolonged irradiation, which is of concern in dosimetry of dynamic deliveries. The EPID was applied to the verification of collimator position using a specially constructed camera interface that triggered recording of the cumulative MU. The EPID was also assessed as a method of measuring the integrated dose distribution delivered during a dynamic sequence, and a method proposed to overcome unreliable triggering of image acquisition in such cases. Dark current and persistence of the camera target were found to complicate measurements. Images were also found to exhibit optical scattering, which is an inherent characteristic of camera- based EPIDs. Results of a physical means of reducing the effect using an optical rejection screen were compared to an ionisation chamber for static and dynamic cases, and it was shown that the optical rejection screen is limited in its effectiveness in removing optical scatter. Dose profiles obtained from the EPID agree with ionisation chamber measurements in-air within 6 % for plain fields, and within 15-25 % for static and dynamically produced wedged fields. It was concluded that both approaches studied can be applied to the verification of IMRT but with limitations, and that an ideal system has yet to be found.
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Markovic, Miljenko. "Comparison of IMRT delivery methods a thesis /." San Antonio : UTHSC, 2008. http://learningobjects.library.uthscsa.edu/cdm4/item_viewer.php?CISOROOT=/theses&CISOPTR=58&CISOBOX=1&REC=13.

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Taylor, Alexandra. "Intensity-modulated radiotherapy for cervical cancer : optimising target volume definition and radiotherapy delivery." Thesis, University of London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510901.

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Bhide, Shreeang Arvind. "Optimization of intensity modulated radiotherapy in head and neck cancer." Thesis, Institute of Cancer Research (University Of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511161.

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Lei, Mary Wei-Ching. "Image guided intensity modulated radiotherapy in head and neck cancer." Thesis, University of Surrey, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600034.

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Image Guided Intensity Modulated Radiotherapy (IG-IMRT) incorporates novel imaging strategies into IMRT planning and delivery. FDG-PET/CT imaging may be used to identify potentially radioresistant tumour cell populations in head and neck cancer (HNC). Dose-painting with IMRT is a novel technique which provides an opportunity to widen the therapeutic window by dose escalation to radioresistant subvolumes. The purpose of this thesis was to evaluate the feasibility of th is technique, to provide methodology for identification of the FDG-avid region and to inform on a reasonable dose level to use in a future phase I clinical study investigating dose-painting to the FDG-avid target volume. This technique requires confidence in the quality of geometric and dosimetric accuracy of delivery and this issue was investigated in this thesis. Pre-clinical work included a comparison of five different FDG segmentation techniques. One of these techniques was used to identify the FOG-avid biological volume selected to receive dose-painting with IMRT in a planning study. Four dose levels were tested. Radiobiological modelling was used to determine an optimal dose level as the basis for a future clinical study and to determine the impact of using different FDG segmentation techniques. A clinical study was performed in patients with HNC to compare in -room volumetric imaging - cone beam computed tomography (CBCT) - with planar kilovoltage (kV) electronic portal imaging (EPI) for aspects of image guidance and to inform on appropriate planning margins. Pre-clinical work suggested that dose-painting with IMRT to the FOG-avid subvolume would be associated with increases in estimated tumour control probability (TCP) and with acceptable increases in normal tissue complication probability (NTCP). Verification using CBCT provided accurate data to guide treatment delivery and appropriate planning margins. The findings reported in this thesis provide valuable information that will inform the design of future clinical studies.
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Books on the topic "Intensity modulated radiotherapy"

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Intensity-modulated radiation therapy. Bristol: Institute of Physics Pub., 2001.

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C, Roeske John, ed. Intensity modulated radiation therapy: A clinical perspective. Hamilton: BC Decker, 2005.

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Jatinder, Palta, and Mackie T. Rock, eds. Intensity-modulated radiation therapy: The state of the art : American Association of Physicists in Medicine 2003 Summer School Proceedings, Colorado College, Colorado Springs, Colorado, June 22-26, 2003. Madison, WI: Published for the American Association of Physicists in Medicine by Medical Physics Pub., 2003.

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Nishimura, Yasumasa, and Ritsuko Komaki. Intensity-Modulated Radiation Therapy: Clinical Evidence and Techniques. Springer, 2015.

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Rowbottom, Carl. Treatment delivery, intensity-modulated radiotherapy, and image-guided radiotherapy. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199696567.003.0003.

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Chapter 3 discusses how successful delivery of external beam radiotherapy involves a number of complex processes beginning with the decision by the clinical oncologist to use radiotherapy as part of the patient’s cancer management, through the preparation and planning of the patient’s treatment, to the verification of the patient position and radiation dose delivered at the time of treatment.
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A, Purdy James, ed. 3-D conformal and intensity modulated radiation therapy. Madison, WI: Advanced Medical Publishing, 2001.

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Chao, K. S. Clifford, Smith Apisarnthanarax, and Gokhan Ozyigit. Practical Essentials of Intensity Modulated Radiation Therapy. 2nd ed. Lippincott Williams & Wilkins, 2004.

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Clifford, Chao K. S., Apisarnthanarax Smith, and Ozyigit Gokhan, eds. Practical essentials of intensity modulated radiation therapy. 2nd ed. Philadelphia: Lippincott Williams & Wilkins, 2005.

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Practical Essentials of Intensity Modulated Radiation Therapy. Lippincott Williams & Wilkins, 2013.

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Intensity Modulated Radiation Therapy for Head and Neck Cancers. Lippincott Williams & Wilkins, 2002.

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Book chapters on the topic "Intensity modulated radiotherapy"

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Koontz, Bridget F., Devon Godfrey, and W. Robert Lee. "Intensity-Modulated Radiotherapy." In Prostate Cancer: A Comprehensive Perspective, 749–59. London: Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-2864-9_63.

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Kairn, Tanya. "Intensity-modulated radiotherapy and volumetric-modulated arc therapy." In Radiochromic Film, 137–64. Boca Raton, FL : CRC Press, Taylor & Francis Group, [2017] |: CRC Press, 2017. http://dx.doi.org/10.1201/9781315154879-8.

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Fenwick, John D., Stephen W. Riley, and Alison J. D. Scott. "Advances in Intensity-Modulated Radiotherapy Delivery." In Cancer Treatment and Research, 189–210. Boston, MA: Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-36744-6_10.

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Chapet, Olivier, Corina Udrescu, and Ciprian Enachescu. "Intensity Modulated Radiotherapy for Prostate Cancer." In Management of Prostate Cancer, 143–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-27597-5_12.

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Solberg, Timothy D., Timothy J. Paul, Nzhde N. Agazaryan, Ted Urmanita, Alonso R. Arellano, Jorge Llacer, Rex A. Boone, et al. "Dosimetry of Gated Intensity Modulated Radiotherapy." In The Use of Computers in Radiation Therapy, 286–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59758-9_109.

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Kollmeier, Marisa A., and Michael J. Zelefsky. "Intensity-Modulated Radiation Therapy for Clinically Localized Prostate Cancer." In Radiotherapy in Prostate Cancer, 95–102. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/174_2013_930.

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Liu, Wei. "Robustness Quantification and Worst-Case Robust Optimization in Intensity-Modulated Proton Therapy." In Particle Radiotherapy, 139–55. New Delhi: Springer India, 2016. http://dx.doi.org/10.1007/978-81-322-2622-2_10.

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Guerrero Urbano, M. T., C. H. Clark, M. Bidmead, D. P. Dearnaley, K. J. Harrington, and C. M. Nutting. "Intensity Modulated Radiotherapy in Cancer of the Larynx." In Image-Guided IMRT, 335–44. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/3-540-30356-1_26.

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Marcu, Loredana, Eva Bezak, and Barry Allen. "Intensity modulated radiotherapy: radiobiology and physics aspects of treatment." In Biomedical Physics in Radiotherapy for Cancer, 183–224. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-733-4_8.

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Yıldız, Ferah, Gozde Yazici, Pervin Hurmuz, and Ali Dogan. "Forward Planning Intensity Modulated Radiation Therapy Techniques." In Principles and Practice of Modern Radiotherapy Techniques in Breast Cancer, 229–41. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5116-7_18.

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Conference papers on the topic "Intensity modulated radiotherapy"

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"Polycrystalline CVD diamond dosimeters for Intensity Modulated Radiotherapy (IMRT)." In 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC). IEEE, 2013. http://dx.doi.org/10.1109/nssmic.2013.6829853.

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OELFKE, U. "INTENSITY MODULATED RADIOTHERAPY WITH HIGH ENERGY PHOTON AND HADRON BEAMS." In Proceedings of the 8th Conference. WORLD SCIENTIFIC, 2004. http://dx.doi.org/10.1142/9789812702708_0061.

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Avelino, S. R., Luis Felipe O. Silva, and C. J. Miosso. "Use of 3D-printers to create Intensity-Modulated Radiotherapy Compensator Blocks." In 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6347293.

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Zhu, Lin, Ling-Hong Zhou, Xin Zhen, Wenting Lu, Zhuoyu Wang, and Shuxu Zhang. "Research on Two Kinds of Convolution Kernels in Intensity Modulated Radiotherapy." In 2008 2nd International Conference on Bioinformatics and Biomedical Engineering (ICBBE '08). IEEE, 2008. http://dx.doi.org/10.1109/icbbe.2008.900.

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Leonard, CE, RD Sobus, S. Fryman, S. Sedlacek, J. Kercher, J. Widner, L. Asmar, et al. "Abstract P1-10-03: A randomized trial of accelerated breast radiotherapy utilizing either 3-dimensional radiotherapy versus intensity modulated radiotherapy." In Abstracts: 2016 San Antonio Breast Cancer Symposium; December 6-10, 2016; San Antonio, Texas. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.sabcs16-p1-10-03.

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Chen, Chao-min, Mu-Tao Tang, Ling-Hong Zhou, Zhuo-Yu Wang, Qing-Wen Lv, and Hua-bin Sun. "Implementation of Inverse Planning Optimization in Intensity Modulated Radiotherapy Using Genetic Algorithms." In 2008 2nd International Conference on Bioinformatics and Biomedical Engineering (ICBBE '08). IEEE, 2008. http://dx.doi.org/10.1109/icbbe.2008.654.

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Amine, Wassim El, Laurent Bartolucci, Camille Adrien, Marie Lejars, Alain Fourquet, Marion Vaillant, Magalie Robilliard, et al. "Abstract P4-12-32: Intensity modulated radiotherapy (IMRT) for breast and lymph node irradiation." In Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-p4-12-32.

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Abbassi, Louisa Marie, Alexandre Arsène-Henry, and Youlia M. Kirova. "Abstract P4-12-27: Dosimetric impact of axillary irradiation: Comparison between 3D-conformal radiotherapy and two types of intensity-modulated radiotherapy." In Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-p4-12-27.

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Page, Ryan F., Natalie L. Abbott, Josh Davies, Emma L. Dyke, Heather J. Randles, Jaap J. Velthuis, Sally Fletcher, et al. "Towards using a Monolithic Active Pixel Sensor for in-vivo beam monitoring of Intensity Modulated Radiotherapy." In 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference (2012 NSS/MIC). IEEE, 2012. http://dx.doi.org/10.1109/nssmic.2012.6551501.

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Huo, D., T. Czechura, DJ Winchester, DP Winchester, and K. Yao. "Abstract P5-14-09: Brachytherapy, 3-dimentional conformal radiotherapy, and intensity modulated radiotherapy for breast cancer patients undergoing breast conservation: Effectiveness and guideline concordance." In Abstracts: Thirty-Sixth Annual CTRC-AACR San Antonio Breast Cancer Symposium - Dec 10-14, 2013; San Antonio, TX. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/0008-5472.sabcs13-p5-14-09.

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Reports on the topic "Intensity modulated radiotherapy"

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Leavitt, Dennis D., and David K. Gaffney. Optimization of Breast Cancer Treatment by Dynamic Intensity Modulated Electron Radiotherapy. Fort Belvoir, VA: Defense Technical Information Center, October 2002. http://dx.doi.org/10.21236/ada412101.

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Seravalli, E., L. Van Battum, M. Van Gellekom, A. Houweling, J. Kaas, M. Kuik, E. Loef, J. De Pooter, T. Raaben, and W. De Vries. NCS Report 28: National Audit of Quality Assurance for Intensity Modulated Radiotherapy and Volumetric Modulated Arc Therapy. Delft: NCS, March 2018. http://dx.doi.org/10.25030/ncs-028.

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Van der Wal, E., J. Wiersma, A. H. Ausma, J. P. Cuijpers, M. Tomsej, L. J. Bos, G. Pittomvils, L. Murrer, and J. B. Van de Kamer. NCS Report 22: Code of practice for the quality assurance and control for intensity modulated radiotherapy. Delft: NCS, June 2013. http://dx.doi.org/10.25030/ncs-022.

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Van der Wal, E., J. Wiersma, A. H. Ausma, J. P. Cuijpers, M. Tomsej, L. J. Bos, G. Pittomvils, L. Murrer, and J. B. Van de Kamer. NCS Report 22: Code of practice for the quality assurance and control for intensity modulated radiotherapy. Delft: NCS, June 2013. http://dx.doi.org/10.25030/ncs-22.

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