Academic literature on the topic 'Integrative conjugative element'
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Journal articles on the topic "Integrative conjugative element"
Iannelli, Francesco, Francesco Santoro, Marco R. Oggioni, and Gianni Pozzi. "Nucleotide Sequence Analysis of Integrative Conjugative Element Tn5253of Streptococcus pneumoniae." Antimicrobial Agents and Chemotherapy 58, no. 2 (December 2, 2013): 1235–39. http://dx.doi.org/10.1128/aac.01764-13.
Full textRingwald, Kenneth, and Jeffrey Gardner. "The Bacteroides thetaiotaomicron Protein Bacteroides Host Factor A Participates in Integration of the Integrative Conjugative Element CTnDOT into the Chromosome." Journal of Bacteriology 197, no. 8 (February 2, 2015): 1339–49. http://dx.doi.org/10.1128/jb.02198-14.
Full textLee, Catherine A., and Alan D. Grossman. "Identification of the Origin of Transfer (oriT) and DNA Relaxase Required for Conjugation of the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis." Journal of Bacteriology 189, no. 20 (August 10, 2007): 7254–61. http://dx.doi.org/10.1128/jb.00932-07.
Full textBurrus, Vincent, Yvonne Roussel, Bernard Decaris, and Gérard Guédon. "Characterization of a Novel Integrative Element, ICESt1, in the Lactic Acid BacteriumStreptococcus thermophilus." Applied and Environmental Microbiology 66, no. 4 (April 1, 2000): 1749–53. http://dx.doi.org/10.1128/aem.66.4.1749-1753.2000.
Full textBelhocine, Kamila, Karen K. Yam, and Benoit Cousineau. "Conjugative Transfer of the Lactococcus lactis Chromosomal Sex Factor Promotes Dissemination of the Ll.LtrB Group II Intron." Journal of Bacteriology 187, no. 3 (February 1, 2005): 930–39. http://dx.doi.org/10.1128/jb.187.3.930-939.2005.
Full textBerkmen, Melanie B., Catherine A. Lee, Emma-Kate Loveday, and Alan D. Grossman. "Polar Positioning of a Conjugation Protein from the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis." Journal of Bacteriology 192, no. 1 (September 4, 2009): 38–45. http://dx.doi.org/10.1128/jb.00860-09.
Full textSmyth, Davida S., and D. Ashley Robinson. "Integrative and Sequence Characteristics of a Novel Genetic Element, ICE6013, in Staphylococcus aureus." Journal of Bacteriology 191, no. 19 (July 31, 2009): 5964–75. http://dx.doi.org/10.1128/jb.00352-09.
Full textHeather, Zoe, Matthew T. G. Holden, Karen F. Steward, Julian Parkhill, Lijiang Song, Gregory L. Challis, Carl Robinson, Nicholas Davis-Poynter, and Andrew S. Waller. "A novel streptococcal integrative conjugative element involved in iron acquisition." Molecular Microbiology 70, no. 5 (December 2008): 1274–92. http://dx.doi.org/10.1111/j.1365-2958.2008.06481.x.
Full textTaviani, Elisa, Christopher J. Grim, Jongsik Chun, Anwar Huq, and R. R. Colwell. "Genomic analysis of a novel integrative conjugative element inVibrio cholerae." FEBS Letters 583, no. 22 (October 20, 2009): 3630–36. http://dx.doi.org/10.1016/j.febslet.2009.10.041.
Full textDel Grosso, Maria, Romina Camilli, Ermanno Rizzi, Alessandro Pietrelli, Gianluca De Bellis, and Annalisa Pantosti. "ICESpy009, a Conjugative Genetic Element Carryingmef(E) in Streptococcus pyogenes." Antimicrobial Agents and Chemotherapy 60, no. 7 (April 11, 2016): 3906–12. http://dx.doi.org/10.1128/aac.03082-15.
Full textDissertations / Theses on the topic "Integrative conjugative element"
SANTORO, FRANCESCO. "Functional characterization of the pneumococcal Integrative Conjugative Element Tn5253." Doctoral thesis, Università di Siena, 2017. http://hdl.handle.net/11365/1005925.
Full textHarden, Mark Michael Jr. "Interactions between an integrative and conjugative element and its bacterial host." Thesis, Massachusetts Institute of Technology, 2021. https://hdl.handle.net/1721.1/130662.
Full textCataloged from the official PDF of thesis.
Includes bibliographical references.
Conjugative elements are mobile genetic elements that can transfer from a donor bacterium to a recipient via an element-encoded type IV secretion system. Integrative and conjugative elements (ICEs) are an abundant class of conjugative element. ICEs are typically integrated into the bacterial host chromosome, but under certain conditions, or stochastically, they can excise from the chromosome and transfer to a recipient. ICEs likely interact with their bacterial host at every stage of their life cycle, but few of these interactions have been characterized. In this work I sought to 1) identify bacterial host factors necessary for efficient transfer of the integrative and conjugative element ICEBs1 to a recipient, and 2) determine whether the ICEBs1-encoded cell wall-modifying enzyme CwlT acts on the cell wall of the donor bacterium, the recipient bacterium, or both.
I used CRISPR interference to induce a knockdown of individual essential Bacillus subtilis genes, and then screened for gene knockdowns that caused an acute defect in transfer of ICEBs1. I found that wall teichoic acids were necessary in both ICEBs1 donors and recipients for efficient conjugative transfer. I found that depletion of wall teichoic acids caused cells involved in ICEBs1 conjugation to sustain lethal envelope damage caused by active conjugation machinery. Conjugative elements must bypass the cell wall of both the donor and recipient cells in a mating pair. Conjugative elements encode cell wall hydrolases that are required for efficient transfer, which are presumed to partly degrade the cell wall of the donor bacterium during conjugation. In order to investigate the role of the ICEBs1-encoded cell wall hydrolase CwlT in conjugation, I generated cell wall-less (L-form) strains of B. subtilis which could donate or receive ICEBs1.
In the absence of either the donor or recipient cell wall, CwlT was dispensable for efficient transfer. This finding indicates that CwlT acts on both the donor and recipient cell wall in a mating pair.
by Mark Michael Harden, Jr.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Biology
Avello, Monika M. M. (Monika Maria Masumi). "Characterization of an exclusion mechanism in an integrative and conjugative element in Bacillus subtilis." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/119980.
Full textCataloged from PDF version of thesis.
Includes bibliographical references.
Horizontal gene transfer is the acquisition of new genetic material that can confer novel phenotypes to bacteria and contribute to their evolution. Conjugation is an important mechanism of horizontal gene transfer that involves the direct transfer of DNA between two cells and is mediated by mobile genetic elements encoding type IV secretion systems. Conjugative elements prevent redundant transfer by a mechanism known as exclusion that inhibits their cognate secretion systems. Exclusion is prevalent among conjugative elements, suggesting it is advantageous and potentially essential. Yet very few exclusion mechanisms are characterized, and the advantages they provide are not well understood. My work characterizes the exclusion mechanism of an integrative and conjugative element found in a Gram-positive bacterium. In combination with several other studies, my results point to a potentially conserved mechanism and novel benefits of this phenomenon, furthering our understanding of how mobile genetic elements regulate their transfer, impact their bacterial hosts, and mediate horizontal gene transfer.
by Monika M. M. Avello.
Ph. D.
fox, Valeria. "Mobile genetic elements carrying stress response systems, antibiotic resistance determinants, and catabolic pathways." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1159250.
Full textCarraro, Nicolas. "Analyse comparative de la dynamique de deux éléments intégratifs conjugatifs de streptococcus thermophilus." Thesis, Nancy 1, 2011. http://www.theses.fr/2011NAN10080/document.
Full textIntegrative and Conjugative Elements (ICEs) are genomic islands, which excise from the chromosome, self-transfer by conjugation and integrate. They harbor a modular organization: genes and sequences involved in the same biological process are grouped in the same region. This work concerns the modality of transfer and maintenance of ICESt1 and ICESt3, two ICEs of Streptococcus thermophilus that share closely related core region. ICESt1 excises much less frequently than ICESt3. Nevertheless, excision of the two elements is activated by the same stimuli (DNA damage, stationary phase and/or cell density) and depends of the host strain. Bioinformatical and transcriptional analyses highlight several differences in their organization. However, each of these two ICEs would encode two different regulators, cI and ImmR, suggesting that a complex and original pathway govern to ICESt1' and ICESt3' regulation. This regulation would be shared with numerous ICEs that we identified in the genome of various commensal or pathogenic streptococci. According to the original definition, ICE's maintenance would be exclusively due to their integration in the host chromosome, and ICEs would not be able of extracellular replication. However, in addition to the induction of ICESt3' excision and transfer, DNA damage cause replication of its extrachromosomal form. This unexpected property is encoded by the core region and would be implicated in the maintenance of the element. Comparision with data recently published on other ICEs suggest that intracellular replication could be involved in the maintenance of numerous ICEs, besides their integration
Eidam, Christopher [Verfasser]. "Molecular analysis of multiresistant Mannheimia haemolytica isolates with particular reference to novel macrolide resistance genes and variants of the integrative and conjugative element ICEPmu1 / Christopher Eidam." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2014. http://d-nb.info/106486256X/34.
Full textSilva, Miriam Lopes da. "Detecção e caracterização de elementos conjugativos integrativos em bactérias isoladas de amostras ambientais." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/6/6135/tde-14052014-155858/.
Full textRecognition of antimicrobial resistance as an emerging phenomenon in public health has been a problem worldwide. The abuse in the use of antibiotics in human and veterinary medicine, and agriculture, has caused an increase in the diversity of resistant microorganisms, reflecting in treatment failure. The mechanisms of antibiotic resistance in microorganisms are primarily mediated by genes acquired from exogenous DNA. The dynamics of the horizontal transfer is performed by mobile genetic elements which carry resistance genes. The wide distribution of these structures, such as the SXT element originally isolated from V. cholerae, has contributed to the spread of specific clonal complexes in certain geographical areas. This pioneering study in Brazil researched the presence of SXT elements in the group of bacterial species in environmental gamma-proteobacteria species, determined their structural and functional characteristics, including genes for resistance to antibiotics and the antibiotic susceptibility among bacterial isolates that harbor them. The result was the classification of 43 SXT elements found in Brazil, by comparison with those found in the literature. Among the SXT elements found, four are sheltered by Morganella morganii, unprecedented in the literature. Knowledge of bacterial evolution is an important to establish effective strategies to control and treat infections without increasing the selective pressure on microorganisms, as well as a precise instrument and very important tool to support epidemiological studies.
Wright, Laurel D. "Autonomous replication of integrative and conjugative elements." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106738.
Full textCataloged from PDF version of thesis.
Includes bibliographical references.
Mobile genetic elements facilitate movement of genes, including those conferring antibiotic resistance and other traits, between bacteria. Integrative and conjugative elements (ICEs), also known as conjugative transposons, are a large family of mobile genetic elements that can transfer between neighboring cells. ICEs are found integrated in the chromosome of their host bacterium, where they are transmitted to daughter cells by chromosomal replication and cell division. Under certain conditions, ICE DNA will excise and form a circular plasmid-like intermediate. It was previously thought that ICEs were incapable of autonomous replication. However, my research, along with the work of others, shows that ICEs can replicate autonomously, and that many ICEs utilize a rolling circle replication mechanism. Plasmids and phages that use rolling circle replication encode a single strand origin (sso) that enhances priming of DNA synthesis. We identified a functional single strand origin, sso1, in the integrative and conjugative element ICEBs1 of Bacillus subtilis. Genetic analyses indicated that ICEBs1 uses sso1 and at least one other region for second strand DNA synthesis. Sso activity was important for autonomous, rolling circle replication of ICEBs1 in host cells, and for stable acquisition of the element in new host cells. I also showed that the broad-host range ICE Tn916 replicates autonomously by a rolling circle mechanism. Replication of Tn916 was dependent on the relaxase encoded by Tn916 orf20. The origin of transfer of Tn916, oriT(916), also functioned as an origin of replication. I found that the relaxase (Orf20) and the two putative helicase processivity factors (Orf22 and Orf23) encoded by Tn916 likely interact in a complex to facilitate replication. Lastly, I identified a functional single strand origin of replication (sso) in Tn916 that I predict primes second strand synthesis during rolling circle replication. The importance of autonomous replication by rolling circle in the ICE lifecycle and horizontal gene transfer processes is discussed.
by Laurel D. Wright.
Ph. D.
Haskett, Timothy L. "Discovery and characterisation of tripartite Integrative & Conjugative Elements." Thesis, Haskett, Timothy L. (2018) Discovery and characterisation of tripartite Integrative & Conjugative Elements. PhD thesis, Murdoch University, 2018. https://researchrepository.murdoch.edu.au/id/eprint/41086/.
Full textStagg, Georgina. "Creation and characterisation of genetically-marked Mesorhizobium integrative and conjugative elements." Thesis, Stagg, Georgina (2018) Creation and characterisation of genetically-marked Mesorhizobium integrative and conjugative elements. Honours thesis, Murdoch University, 2018. https://researchrepository.murdoch.edu.au/id/eprint/42888/.
Full textBooks on the topic "Integrative conjugative element"
Mullany, Peter, and Adam P. Roberts. Bacterial Integrative Mobile Genetic Elements. Taylor & Francis Group, 2022.
Find full textBacterial Integrative Mobile Genetic Elements. Taylor & Francis Group, 2013.
Find full textMullany, Peter, and Adam P. Roberts. Bacterial Integrative Mobile Genetic Elements. Taylor & Francis Group, 2022.
Find full textMullany, Peter, and Adam P. Roberts. Bacterial Integrative Mobile Genetic Elements. Taylor & Francis Group, 2022.
Find full textBook chapters on the topic "Integrative conjugative element"
Berkmen, Melanie B., Stephanie J. Laurer, Bridget K. Giarusso, and Rodrigo Romero. "The Integrative and Conjugative Element ICEBs1 of Bacillus subtilis." In Bacterial Integrative Mobile Genetic Elements, 201–16. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-12.
Full textCury, Jean, Sophie S. Abby, Olivia Doppelt-Azeroual, Bertrand Néron, and Eduardo P. C. Rocha. "Identifying Conjugative Plasmids and Integrative Conjugative Elements with CONJscan." In Horizontal Gene Transfer, 265–83. New York, NY: Springer US, 2019. http://dx.doi.org/10.1007/978-1-4939-9877-7_19.
Full textCunha, Violette Da, Romain Guérillot, Mathieu Brochet, and Philippe Glaser. "Integrative and Conjugative Elements Encoding DDE Transposases." In Bacterial Integrative Mobile Genetic Elements, 250–60. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-15.
Full textCiric, Lena, Azmiza Jasni, Lisbeth Elvira de Vries, Yvonne Agersø, Peter Mullany, and Adam P. Roberts. "The Tn916/Tn1545 Family of Conjugative Transposons." In Bacterial Integrative Mobile Genetic Elements, 153–70. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-9.
Full textGarriss, Geneviéve, and Vincent Burrus. "Integrating Conjugative Elements of the SXT/R391 Family." In Bacterial Integrative Mobile Genetic Elements, 217–34. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-13.
Full textSalyers, Abigail A., Jeffrey F. Gardner, and Nadja B. Shoemaker. "Excision and Transfer of Bacteroides Conjugative Integrated Elements." In Bacterial Integrative Mobile Genetic Elements, 235–49. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-14.
Full textEsnault, Emilie, Alain Raynal, and Jean-Luc Pernodet. "pSAM2, a Paradigm for a Family of Actinomycete Integrative and Conjugative Elements." In Bacterial Integrative Mobile Genetic Elements, 135–52. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-8.
Full textBurrus, Vincent. "Significance of the SXT/R391 Family of Integrating Conjugative Elements in Vibrio cholerae." In Epidemiological and Molecular Aspects on Cholera, 161–84. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-60327-265-0_9.
Full textArmshaw, Patricia, and J. Tony Pembroke. "UV Stress-Responsive Genes Associated with Enterobacterial Integrative Conjugative Elements of the ICE SXT/R391 Group." In Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria, 517–27. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781119004813.ch48.
Full textChurchward, G., and V. Burrus. "Conjugative Transposons and Integrative and Conjugative Elements ☆." In Reference Module in Life Sciences. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809633-8.06270-1.
Full textConference papers on the topic "Integrative conjugative element"
Grigoriev, M. M., and G. F. Dargush. "A Fast Multi-Level Boundary Element Method for the Steady Heat Diffusion Equation." In ASME 2003 Heat Transfer Summer Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/ht2003-47450.
Full textNoymer, Peter D., Megan U. Hazen, and S. C. Yao. "An Integrated Thermal Science Course for Third-Year Mechanical Engineering Students." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0636.
Full textRahman, Muhammad M., and Santosh K. Mukka. "Confined Liquid Jet Impingement on a Plate With Discrete Heating Elements." In ASME 2005 Summer Heat Transfer Conference collocated with the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems. ASMEDC, 2005. http://dx.doi.org/10.1115/ht2005-72408.
Full textKhalilollahi, Amir, and Russell L. Warley. "Thermal Stress Reduction and Optimization for Orthotropic Composite Boards." In ASME 2005 Summer Heat Transfer Conference collocated with the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems. ASMEDC, 2005. http://dx.doi.org/10.1115/ht2005-72570.
Full textHouck, Lonnie, DeAnna Sewell, Megan Burke, and Gregory Vogel. "A Fully Coupled Aero, Thermal, and Structural Lifetime Model for Root Cause Failure Analysis and Robust Redesign of an Industrial F Class Gas Turbine Blade." In ASME Turbo Expo 2015: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/gt2015-42505.
Full textAl-Dojayli, Maher, Ellen Chan, Sunny Leung, Hani Naguib, Francis Dawson, Vincent Adinkrah, and Laszlo Lakatos-Hayward. "Three-Dimensional Multiphysics Analyses of a CPU Integrated Thermal Heat Sink." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-40649.
Full textBarrett, G. R., A. K. Powell, and T. J. Hall. "Dynamic Solutions and Instabilities of the Four-wave Mixing Interaction Utilising the Underlying SU(2) Group Symmetry." In Photorefractive Materials, Effects, and Devices II. Washington, D.C.: Optica Publishing Group, 1991. http://dx.doi.org/10.1364/pmed.1991.tuc21.
Full textSmith, Evan Oscar, and Andrew J. Neely. "The Effect of Aircraft Integration Design on Gas Turbine Shaft Thermal Bow and the Newkirk Effect." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-25511.
Full textAchar P. L., Sukshitha, Huanyu Liao, and Ganesh Subbarayan. "Comparative Evaluation of Algorithms for Achieving Ultrapacked Thermal Greases: Microstructural Models and Effective Behavior." In ASME 2019 International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/ipack2019-6501.
Full textSmith, E. O., A. J. Neely, and A. P. Butcher. "Experimental Observations of Thermal Bow due to Natural Convection on a Gas Turbine Compressor Rotor Shaft Analogue." In ASME Turbo Expo 2016: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/gt2016-56800.
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