Books on the topic 'Inner retina'

L’anno 2020 ha visto svilupparsi una crisi senza precedenti a causa della pandemia. A fronte di questa situazione, l’edizione 2020 dell’Osservatorio vuole proporre una riflessione su come le reti d’imprese possano rappresentare uno strumento di resilienza delle imprese, guardando alle relazioni inter-organizzative come strumento di flessibilità, cambiamento e adattamento. L’edizione 2020 dell’Osservatorio sviluppa un approfondimento sulla relazione tra il funzionamento della rete e la performance delle imprese in rete ed è arricchito da alcuni approfondimenti settoriali. I risultati presentati aiuteranno i manager a massimizzare le opportunità offerte dalla rete ed i policy maker ad orientare in modo ancora più efficace l’utilizzo dei contratti di rete come strumento di resilienza.

Our political times appear unstable: Liberal democracy is struggling to retain its inner balance and is being destabilised by both internal and external forces. How can stability be achieved — and what is stability? When does stability become undemocratic? And what can we learn from historical diagnoses of crises and instability for current debates on political, economic and international stability? Political theory and the history of political thought on stability offer answers to these questions: They examine stability as a fundamental norm of Democracy — and destabilise ideas of overly static stability. With contributions by Tobias Albrecht, Vincent August, Manuel Becker, Andreas Braune, Frank Decker, Verena Frick, Johannes Gerschewski, Jens Hacke, Eva Hausteiner, Frauke Höntzsch, Michael Kubiak, Sebastian Lange, Philip Manow, Christoph Michael, Tobias Schottdorf, Veith Selk, Grit Straßenberger, RiekeTrimcev, Felix Wassermann.

The airway lining fluid is a biphasic layer covering the respiratory tract epithelium. It has antimicrobial and immunomodulatory properties, and it is formed by a gel-phase (mucus), and a low-viscosity inner layer (sol-phase) that provides lubrication for ciliary beating. Mucus is continuously cleared from the airways through the ciliated epithelium and via the two-phase gas–liquid flow mechanism (i.e. coughing). Mucus production in healthy subjects is approximately 10–100 mL/day. Whereas, mucociliary clearance rates range between 4 and 20 mm/min. Critically-ill, mechanically-ventilated patients often retain mucus. Several chest physiotherapy techniques are applied to promote mucus clearance in these patients. The role of chest physiotherapy in mechanically-ventilated patients is debated, due to the lack of evidence from well-designed clinical trials. Retained mucus is aspirated through tracheobronchial suctioning. Closed suctioning is beneficial in patients with severe lung failure and at risk of alveolar collapse upon ventilator disconnection.

For a generation, this book has stood as the authoritative account of an often misunderstood chapter in the history of a celebrated tradition among literary radicals in the United States that began in the Great Depression. Wald’s passionate investigation of over half a century of dissident Marxist thought, Jewish internationalism, fervent political activism, and the complex art of the literary imagination is enriched by more than one hundred personal interviews, unparalleled primary research, and critical interpretations of novels and short stories depicting the inner lives of committed writers and thinkers. Wald's commanding biographical portraits of rebel outsiders, some of whom founded Partisan Review, who mostly became insiders, often Cold War liberals and a few neoconservatives, retains its resonance today. Included is commentary on Max Eastman, Elliot Cohen, Lionel Trilling, Sidney Hook, Tess Slesinger, James Burnham, Meyer Schapiro, Dwight Macdonald, Philip Rahv, Mary McCarthy, James T. Farrell, Irving Kristol, Irving Howe, Hannah Arendt, and more. With a new preface by the author that tracks the rebounding influence of these intellectuals in the era of Occupy and Bernie Sanders, this anniversary edition shows that the trajectory and ideological ordeals of the New York intellectual Left still matters today.

This essay focuses on what Richard Ellis sees as three of the main overlapping trends of transnational “New American Studies.” He contemplates an intra-hemispheric approach to American Studies, a contingent hemispheric approach to American Studies, and a more recent approach attending to globalizing changes in the world order, precipitated by the necessary recognition of a new closeness between the postindustrial state and late corporate capitalism. All rethink space and spatialization, but Ellis also wants to stress the powerful omnipresence of the U.S. state, U.S. multinationals, and U.S. export culture. In order to illustrate his approach, Ellis offers a comparative, inter-hemispheric analysis of two international film co-productions, one Hollywood-style, the other Bollywood-style (Sofia Coppola’s 2003 Lost in Translation and Gurinder Chadha’s 2004 Bride and Prejudice). He ultimately argues that a new kind of approach to USAmerican Studies is necessary, stressing processes of contact, hybridity, exchange, flow, and migration.

Diasporas are transnational communities that have received significant interest from international relations (IR) scholars. Attempts to conceptualize diaspora as a modern analytical term posed a major challenge in terms of drawing a distinction between people on the move—such as migrants, refugees, and seasonal workers—and people who are diasporic members of a transnational community. There are different categories of diaspora: historical (or classical/core) diasporas, modern (or recent) diasporas, incipient diasporas, state-linked diasporas, and stateless diasporas. A widely used system of categorization distinguishes among victim, trade, labor, and imperial diasporas. Most of the diaspora research done today in IR deals with the relations between diasporas and their host state and state of origin. There is also a growing body of literature on the role of diasporas in conflict and peace in the homeland. Recent studies have focused on ethnonational diasporic communities, especially the relations between diasporic kin groups in the homeland and in other states of residence, as well as their influence on the foreign policy of their host states. The study of diasporas presents a few major challenges. For instance, it forces us to rethink the rubrics of state and of nation, to challenge accepted notions of citizenship, and to question existing conceptualizations of the importance of territoriality. It also exacerbates the fuzziness between inner and outer politics in research and practice.

This book throws new light on the reciprocal relationship between political modernization and authoritarianism in Germany over the span of six decades. Election battles were fought so fiercely in Imperial Germany because they reflected two kinds of democratization. Social democratization could not be stopped; but political democratization was opposed by many members of the German bourgeoisie. Frightened by the electoral success of Social Democrats after 1871, anti-democrats deployed many strategies that flew in the face of electoral fairness. They battled socialists, liberals, and Jews at election time, but they also strove to rewrite the electoral rules of the game. Using a regional lens to rethink older assumptions about Germany’s changing political culture, this book focuses as much on contemporary Germans’ perceptions of electoral fairness as on their experiences of voting. It devotes special attention to various semi-democratic voting systems whereby a general and equal suffrage (for the Reichstag) was combined with limited and unequal ones for local and regional parliaments. For the first time, democratization at all three tiers of governance and their reciprocal effects are considered together. Although the bourgeois face of German authoritarianism was nowhere more evident than in the Kingdom of Saxony, this book illustrates how Germans grew to fear the spectre of democracy. Certainly twists and turns lay ahead, yet that fear made it easier for Hitler and the Nazis to inter German democracy in 1933.

This volume is designed to mark the outstanding legacy of Professor Wojciech Sadurski’s scholarship in the field of comparative constitutional law. It provides a rich palette of chapters that aim to rethink the state of the art in this field, in light of the latest challenges to the foundations of liberal constitutionalism. Edited by former doctoral students of Professor Sadurski, the volume transcends the celebration of his major academic contributions by linking his pioneering writings, inter alia on Central and Eastern Europe (CEE), to core dilemmas in the turbulent state of the rule of law in western democracies. It consolidates contributions by numerous current and former students, as well as colleagues and friends around the globe in admiration of his didactic style, tireless work, civil dedication, and priceless commentary influencing the work of generations of constitutional scholars. Besides drawing on Wojciech’s fields of interest, the book aims to provide a full overview of the crucial dilemmas in dealing with the current decline of liberal democracies and populist challenges to the rule of law throughout Europe—events that he predicted early on in his writings about the Jörg Haider affair in Austria and the introduction of Article 7 TEU by the Amsterdam Treaty. The major themes of the chapters are thus as follows: 1. Populism and democratic decline in CEE; 2. The EU role: Article 7 TEU vis-à-vis the rule of law in Hungary and Poland; 3. Constitutional review and militant democracy: between public reason and new forms of populism.

Bones are multifunctional passive organs of movement that supports soft tissue and directly attached muscles. They also protect internal organs and are a reserve of calcium, phosphorus and magnesium. Each bone is covered with periosteum, and the adjacent bone surfaces are covered by articular cartilage. Histologically, the bone is an organ composed of many different tissues. The main component is bone tissue (cortical and spongy) composed of a set of bone cells and intercellular substance (mineral and organic), it also contains fat, hematopoietic (bone marrow) and cartilaginous tissue. Bones are a tissue that even in adult life retains the ability to change shape and structure depending on changes in their mechanical and hormonal environment, as well as self-renewal and repair capabilities. This process is called bone turnover. The basic processes of bone turnover are: • bone modeling (incessantly changes in bone shape during individual growth) following resorption and tissue formation at various locations (e.g. bone marrow formation) to increase mass and skeletal morphology. This process occurs in the bones of growing individuals and stops after reaching puberty • bone remodeling (processes involve in maintaining bone tissue by resorbing and replacing old bone tissue with new tissue in the same place, e.g. repairing micro fractures). It is a process involving the removal and internal remodeling of existing bone and is responsible for maintaining tissue mass and architecture of mature bones. Bone turnover is regulated by two types of transformation: • osteoclastogenesis, i.e. formation of cells responsible for bone resorption • osteoblastogenesis, i.e. formation of cells responsible for bone formation (bone matrix synthesis and mineralization) Bone maturity can be defined as the completion of basic structural development and mineralization leading to maximum mass and optimal mechanical strength. The highest rate of increase in pig bone mass is observed in the first twelve weeks after birth. This period of growth is considered crucial for optimizing the growth of the skeleton of pigs, because the degree of bone mineralization in later life stages (adulthood) depends largely on the amount of bone minerals accumulated in the early stages of their growth. The development of the technique allows to determine the condition of the skeletal system (or individual bones) in living animals by methods used in human medicine, or after their slaughter. For in vivo determination of bone properties, Abstract 10 double energy X-ray absorptiometry or computed tomography scanning techniques are used. Both methods allow the quantification of mineral content and bone mineral density. The most important property from a practical point of view is the bone’s bending strength, which is directly determined by the maximum bending force. The most important factors affecting bone strength are: • age (growth period), • gender and the associated hormonal balance, • genotype and modification of genes responsible for bone growth • chemical composition of the body (protein and fat content, and the proportion between these components), • physical activity and related bone load, • nutritional factors: – protein intake influencing synthesis of organic matrix of bone, – content of minerals in the feed (CA, P, Zn, Ca/P, Mg, Mn, Na, Cl, K, Cu ratio) influencing synthesis of the inorganic matrix of bone, – mineral/protein ratio in the diet (Ca/protein, P/protein, Zn/protein) – feed energy concentration, – energy source (content of saturated fatty acids - SFA, content of polyun saturated fatty acids - PUFA, in particular ALA, EPA, DPA, DHA), – feed additives, in particular: enzymes (e.g. phytase releasing of minerals bounded in phytin complexes), probiotics and prebiotics (e.g. inulin improving the function of the digestive tract by increasing absorption of nutrients), – vitamin content that regulate metabolism and biochemical changes occurring in bone tissue (e.g. vitamin D3, B6, C and K). This study was based on the results of research experiments from available literature, and studies on growing pigs carried out at the Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences. The tests were performed in total on 300 pigs of Duroc, Pietrain, Puławska breeds, line 990 and hybrids (Great White × Duroc, Great White × Landrace), PIC pigs, slaughtered at different body weight during the growth period from 15 to 130 kg. Bones for biomechanical tests were collected after slaughter from each pig. Their length, mass and volume were determined. Based on these measurements, the specific weight (density, g/cm3) was calculated. Then each bone was cut in the middle of the shaft and the outer and inner diameters were measured both horizontally and vertically. Based on these measurements, the following indicators were calculated: • cortical thickness, • cortical surface, • cortical index. Abstract 11 Bone strength was tested by a three-point bending test. The obtained data enabled the determination of: • bending force (the magnitude of the maximum force at which disintegration and disruption of bone structure occurs), • strength (the amount of maximum force needed to break/crack of bone), • stiffness (quotient of the force acting on the bone and the amount of displacement occurring under the influence of this force). Investigation of changes in physical and biomechanical features of bones during growth was performed on pigs of the synthetic 990 line growing from 15 to 130 kg body weight. The animals were slaughtered successively at a body weight of 15, 30, 40, 50, 70, 90, 110 and 130 kg. After slaughter, the following bones were separated from the right half-carcass: humerus, 3rd and 4th metatarsal bone, femur, tibia and fibula as well as 3rd and 4th metatarsal bone. The features of bones were determined using methods described in the methodology. Describing bone growth with the Gompertz equation, it was found that the earliest slowdown of bone growth curve was observed for metacarpal and metatarsal bones. This means that these bones matured the most quickly. The established data also indicate that the rib is the slowest maturing bone. The femur, humerus, tibia and fibula were between the values of these features for the metatarsal, metacarpal and rib bones. The rate of increase in bone mass and length differed significantly between the examined bones, but in all cases it was lower (coefficient b <1) than the growth rate of the whole body of the animal. The fastest growth rate was estimated for the rib mass (coefficient b = 0.93). Among the long bones, the humerus (coefficient b = 0.81) was characterized by the fastest rate of weight gain, however femur the smallest (coefficient b = 0.71). The lowest rate of bone mass increase was observed in the foot bones, with the metacarpal bones having a slightly higher value of coefficient b than the metatarsal bones (0.67 vs 0.62). The third bone had a lower growth rate than the fourth bone, regardless of whether they were metatarsal or metacarpal. The value of the bending force increased as the animals grew. Regardless of the growth point tested, the highest values were observed for the humerus, tibia and femur, smaller for the metatarsal and metacarpal bone, and the lowest for the fibula and rib. The rate of change in the value of this indicator increased at a similar rate as the body weight changes of the animals in the case of the fibula and the fourth metacarpal bone (b value = 0.98), and more slowly in the case of the metatarsal bone, the third metacarpal bone, and the tibia bone (values of the b ratio 0.81–0.85), and the slowest femur, humerus and rib (value of b = 0.60–0.66). Bone stiffness increased as animals grew. Regardless of the growth point tested, the highest values were observed for the humerus, tibia and femur, smaller for the metatarsal and metacarpal bone, and the lowest for the fibula and rib. Abstract 12 The rate of change in the value of this indicator changed at a faster rate than the increase in weight of pigs in the case of metacarpal and metatarsal bones (coefficient b = 1.01–1.22), slightly slower in the case of fibula (coefficient b = 0.92), definitely slower in the case of the tibia (b = 0.73), ribs (b = 0.66), femur (b = 0.59) and humerus (b = 0.50). Bone strength increased as animals grew. Regardless of the growth point tested, bone strength was as follows femur > tibia > humerus > 4 metacarpal> 3 metacarpal> 3 metatarsal > 4 metatarsal > rib> fibula. The rate of increase in strength of all examined bones was greater than the rate of weight gain of pigs (value of the coefficient b = 2.04–3.26). As the animals grew, the bone density increased. However, the growth rate of this indicator for the majority of bones was slower than the rate of weight gain (the value of the coefficient b ranged from 0.37 – humerus to 0.84 – fibula). The exception was the rib, whose density increased at a similar pace increasing the body weight of animals (value of the coefficient b = 0.97). The study on the influence of the breed and the feeding intensity on bone characteristics (physical and biomechanical) was performed on pigs of the breeds Duroc, Pietrain, and synthetic 990 during a growth period of 15 to 70 kg body weight. Animals were fed ad libitum or dosed system. After slaughter at a body weight of 70 kg, three bones were taken from the right half-carcass: femur, three metatarsal, and three metacarpal and subjected to the determinations described in the methodology. The weight of bones of animals fed aa libitum was significantly lower than in pigs fed restrictively All bones of Duroc breed were significantly heavier and longer than Pietrain and 990 pig bones. The average values of bending force for the examined bones took the following order: III metatarsal bone (63.5 kg) <III metacarpal bone (77.9 kg) <femur (271.5 kg). The feeding system and breed of pigs had no significant effect on the value of this indicator. The average values of the bones strength took the following order: III metatarsal bone (92.6 kg) <III metacarpal (107.2 kg) <femur (353.1 kg). Feeding intensity and breed of animals had no significant effect on the value of this feature of the bones tested. The average bone density took the following order: femur (1.23 g/cm3) <III metatarsal bone (1.26 g/cm3) <III metacarpal bone (1.34 g / cm3). The density of bones of animals fed aa libitum was higher (P<0.01) than in animals fed with a dosing system. The density of examined bones within the breeds took the following order: Pietrain race> line 990> Duroc race. The differences between the “extreme” breeds were: 7.2% (III metatarsal bone), 8.3% (III metacarpal bone), 8.4% (femur). Abstract 13 The average bone stiffness took the following order: III metatarsal bone (35.1 kg/mm) <III metacarpus (41.5 kg/mm) <femur (60.5 kg/mm). This indicator did not differ between the groups of pigs fed at different intensity, except for the metacarpal bone, which was more stiffer in pigs fed aa libitum (P<0.05). The femur of animals fed ad libitum showed a tendency (P<0.09) to be more stiffer and a force of 4.5 kg required for its displacement by 1 mm. Breed differences in stiffness were found for the femur (P <0.05) and III metacarpal bone (P <0.05). For femur, the highest value of this indicator was found in Pietrain pigs (64.5 kg/mm), lower in pigs of 990 line (61.6 kg/mm) and the lowest in Duroc pigs (55.3 kg/mm). In turn, the 3rd metacarpal bone of Duroc and Pietrain pigs had similar stiffness (39.0 and 40.0 kg/mm respectively) and was smaller than that of line 990 pigs (45.4 kg/mm). The thickness of the cortical bone layer took the following order: III metatarsal bone (2.25 mm) <III metacarpal bone (2.41 mm) <femur (5.12 mm). The feeding system did not affect this indicator. Breed differences (P <0.05) for this trait were found only for the femur bone: Duroc (5.42 mm)> line 990 (5.13 mm)> Pietrain (4.81 mm). The cross sectional area of the examined bones was arranged in the following order: III metatarsal bone (84 mm2) <III metacarpal bone (90 mm2) <femur (286 mm2). The feeding system had no effect on the value of this bone trait, with the exception of the femur, which in animals fed the dosing system was 4.7% higher (P<0.05) than in pigs fed ad libitum. Breed differences (P<0.01) in the coross sectional area were found only in femur and III metatarsal bone. The value of this indicator was the highest in Duroc pigs, lower in 990 animals and the lowest in Pietrain pigs. The cortical index of individual bones was in the following order: III metatarsal bone (31.86) <III metacarpal bone (33.86) <femur (44.75). However, its value did not significantly depend on the intensity of feeding or the breed of pigs.