Journal articles on the topic 'Influenza virus'

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1

Arbo, Antonio. "Influenza: the changing virus." Revista del Instituto de Medicina Tropical 12, no. 2 (December 30, 2017): 1–2. http://dx.doi.org/10.18004/imt/20171221-2.

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2

Juozapaitis, Mindaugas, and Linas Antoniukas. "Influenza virus." Medicina 43, no. 12 (December 8, 2007): 919. http://dx.doi.org/10.3390/medicina43120119.

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Every year, especially during the cold season, many people catch an acute respiratory disease, namely flu. It is easy to catch this disease; therefore, it spreads very rapidly and often becomes an epidemic or a global pandemic. Airway inflammation and other body ailments, which form in a very short period, torment the patient several weeks. After that, the symptoms of the disease usually disappear as quickly as they emerged. The great epidemics of flu have rather unique characteristics; therefore, it is possible to identify descriptions of such epidemics in historic sources. Already in the 4th century BC, Hippocrates himself wrote about one of them. It is known now that flu epidemics emerge rather frequently, but there are no regular intervals between those events. The epidemics can differ in their consequences, but usually they cause an increased mortality of elderly people. The great flu epidemics of the last century took millions of human lives. In 1918–19, during “The Spanish” pandemic of flu, there were around 40–50 millions of deaths all over the world; “Pandemic of Asia” in 1957 took up to one million lives, etc. Influenza virus can cause various disorders of the respiratory system: from mild inflammations of upper airways to acute pneumonia that finally results in the patient’s death. Scientist Richard E. Shope, who investigated swine flu in 1920, had a suspicion that the cause of this disease might be a virus. Already in 1933, scientists from the National Institute for Medical Research in London – Wilson Smith, Sir Christopher Andrewes, and Sir Patrick Laidlaw – for the first time isolated the virus, which caused human flu. Then scientific community started the exhaustive research of influenza virus, and the great interest in this virus and its unique features is still active even today.
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3

Hutchinson, Edward C. "Influenza Virus." Trends in Microbiology 26, no. 9 (September 2018): 809–10. http://dx.doi.org/10.1016/j.tim.2018.05.013.

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4

Freymuth, François. "Virus influenza." EMC - Biologie Médicale 1, no. 1 (January 2006): 1–9. http://dx.doi.org/10.1016/s2211-9698(06)76378-6.

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5

Cottey, Robert, Cheryl A. Rowe, and Bradley S. Bender. "Influenza Virus." Current Protocols in Immunology 42, no. 1 (April 2001): 19.11.1–19.11.32. http://dx.doi.org/10.1002/0471142735.im1911s42.

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6

&NA;. "Influenza virus vaccine/influenza A virus vaccine-H1N1." Reactions Weekly &NA;, no. 1382 (December 2011): 24–25. http://dx.doi.org/10.2165/00128415-201113820-00085.

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7

&NA;. "Influenza A virus vaccine-H1N1/influenza virus vaccine." Reactions Weekly &NA;, no. 1402 (May 2012): 29. http://dx.doi.org/10.2165/00128415-201214020-00104.

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8

&NA;. "Influenza A virus vaccine-H1N1/influenza virus vaccine." Reactions Weekly &NA;, no. 1313 (August 2010): 27. http://dx.doi.org/10.2165/00128415-201013130-00094.

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9

&NA;. "Influenza virus vaccine/influenza A virus vaccine H1N1." Reactions Weekly &NA;, no. 1329 (November 2010): 23. http://dx.doi.org/10.2165/00128415-201013290-00076.

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10

&NA;. "Influenza A virus vaccine H1N1/influenza virus vaccine." Reactions Weekly &NA;, no. 1332 (December 2010): 24–25. http://dx.doi.org/10.2165/00128415-201013320-00080.

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11

&NA;. "Influenza A virus vaccine H1N1/influenza virus vaccine." Reactions Weekly &NA;, no. 1334 (January 2011): 29. http://dx.doi.org/10.2165/00128415-201113340-00101.

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12

&NA;. "Influenza A virus vaccine H1N1/influenza virus vaccine." Reactions Weekly &NA;, no. 1347 (April 2011): 24. http://dx.doi.org/10.2165/00128415-201113470-00078.

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13

&NA;. "Influenza virus vaccine/influenza A virus vaccine H1N1." Reactions Weekly &NA;, no. 1351 (May 2011): 27. http://dx.doi.org/10.2165/00128415-201113510-00090.

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14

&NA;. "Influenza A virus vaccine H1N1/influenza virus vaccine." Reactions Weekly &NA;, no. 1421 (September 2012): 31. http://dx.doi.org/10.2165/00128415-201214210-00102.

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15

Skelton, Raegan M., and Victor C. Huber. "Comparing Influenza Virus Biology for Understanding Influenza D Virus." Viruses 14, no. 5 (May 13, 2022): 1036. http://dx.doi.org/10.3390/v14051036.

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The newest type of influenza virus, influenza D virus (IDV), was isolated in 2011. IDV circulates in several animal species worldwide, causing mild respiratory illness in its natural hosts. Importantly, IDV does not cause clinical disease in humans and does not spread easily from person to person. Here, we review what is known about the host–pathogen interactions that may limit IDV illness. We focus on early immune interactions between the virus and infected host cells in our summary of what is known about IDV pathogenesis. This work establishes a foundation for future research into IDV infection and immunity in mammalian hosts.
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16

Biswas, Siddhartha K., Paul L. Boutz, and Debi P. Nayak. "Influenza Virus Nucleoprotein Interacts with Influenza Virus Polymerase Proteins." Journal of Virology 72, no. 7 (July 1, 1998): 5493–501. http://dx.doi.org/10.1128/jvi.72.7.5493-5501.1998.

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ABSTRACT Influenza virus nucleoprotein (NP) is a critical factor in the viral infectious cycle in switching influenza virus RNA synthesis from transcription mode to replication mode. In this study, we investigated the interaction of NP with the viral polymerase protein complex. Using coimmunoprecipitation with monospecific or monoclonal antibodies, we observed that NP interacted with the RNP-free polymerase protein complex in influenza virus-infected cells. In addition, coexpression of the components of the polymerase protein complex (PB1, PB2, or PA) with NP either together or pairwise revealed that NP interacts with PB1 and PB2 but not PA. Interaction of NP with PB1 and PB2 was confirmed by both coimmunoprecipitation and histidine tagging of the NP-PB1 and NP-PB2 complexes. Further, it was observed that NP-PB2 interaction was rather labile and sensitive to dissociation in 0.1% sodium dodecyl sulfate and that the stability of NP-PB2 interaction was regulated by the sequences present at the COOH terminus of NP. Analysis of NP deletion mutants revealed that at least three regions of NP interacted independently with PB2. A detailed analysis of the COOH terminus of NP by mutation of serine-to-alanine (SA) residues either individually or together demonstrated that SA mutations in this region did not affect the binding of NP to PB2. However, some SA mutations at the COOH terminus drastically affected the functional activity of NP in an in vivo transcription-replication assay, whereas others exhibited a temperature-sensitive phenotype and still others had no effect on the transcription and replication of the viral RNA. These results suggest that a direct interaction of NP with polymerase proteins may be involved in regulating the switch of viral RNA synthesis from transcription to replication.
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17

Tripp, Ralph, and S. Tompkins. "Virus-Vectored Influenza Virus Vaccines." Viruses 6, no. 8 (August 7, 2014): 3055–79. http://dx.doi.org/10.3390/v6083055.

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18

Abdelwhab, E. M., Jutta Veits, and Thomas C. Mettenleiter. "Avian influenza virus NS1." Virulence 4, no. 7 (October 2013): 583–88. http://dx.doi.org/10.4161/viru.26360.

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19

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1376 (November 2011): 18. http://dx.doi.org/10.2165/00128415-201113760-00060.

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20

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1383 (January 2012): 23. http://dx.doi.org/10.2165/00128415-201213830-00077.

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21

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1383 (January 2012): 23. http://dx.doi.org/10.2165/00128415-201213830-00078.

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22

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1385 (January 2012): 26. http://dx.doi.org/10.2165/00128415-201213850-00096.

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23

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1386 (January 2012): 23. http://dx.doi.org/10.2165/00128415-201213860-00080.

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24

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1389 (February 2012): 29. http://dx.doi.org/10.2165/00128415-201213890-00104.

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25

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1391 (March 2012): 26. http://dx.doi.org/10.2165/00128415-201213910-00098.

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26

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1394 (March 2012): 26. http://dx.doi.org/10.2165/00128415-201213940-00094.

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27

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 693 (March 1998): 12. http://dx.doi.org/10.2165/00128415-199806930-00036.

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28

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 723 (October 1998): 8–9. http://dx.doi.org/10.2165/00128415-199807230-00024.

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29

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 764 (August 1999): 9. http://dx.doi.org/10.2165/00128415-199907640-00028.

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30

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1170 (September 2007): 23. http://dx.doi.org/10.2165/00128415-200711700-00060.

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31

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1181 (December 2007): 22. http://dx.doi.org/10.2165/00128415-200711810-00064.

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32

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1189 (February 2008): 23. http://dx.doi.org/10.2165/00128415-200811890-00073.

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33

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1121 (September 2006): 16. http://dx.doi.org/10.2165/00128415-200611210-00053.

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34

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1127 (November 2006): 15. http://dx.doi.org/10.2165/00128415-200611270-00050.

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35

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1131 (December 2006): 22. http://dx.doi.org/10.2165/00128415-200611310-00065.

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36

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1149 (April 2007): 16. http://dx.doi.org/10.2165/00128415-200711490-00049.

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37

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1356 (June 2011): 21–22. http://dx.doi.org/10.2165/00128415-201113560-00072.

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38

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1366 (August 2011): 21. http://dx.doi.org/10.2165/00128415-201113660-00075.

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39

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1367 (September 2011): 24. http://dx.doi.org/10.2165/00128415-201113670-00081.

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40

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1368 (September 2011): 23. http://dx.doi.org/10.2165/00128415-201113680-00082.

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41

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 1374 (October 2011): 20. http://dx.doi.org/10.2165/00128415-201113740-00067.

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42

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 535 (January 1995): 8. http://dx.doi.org/10.2165/00128415-199505350-00033.

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43

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 536 (February 1995): 9. http://dx.doi.org/10.2165/00128415-199505360-00037.

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44

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 545 (April 1995): 9. http://dx.doi.org/10.2165/00128415-199505450-00031.

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45

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 582 (December 1995): 9. http://dx.doi.org/10.2165/00128415-199505820-00020.

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46

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 583 (January 1996): 10. http://dx.doi.org/10.2165/00128415-199605830-00025.

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47

Kida, Hiroshi. "Avian influenza virus." Uirusu 54, no. 1 (2004): 93–96. http://dx.doi.org/10.2222/jsv.54.93.

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48

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 453 (May 1993): 9. http://dx.doi.org/10.2165/00128415-199304530-00035.

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49

&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 474 (October 1993): 7. http://dx.doi.org/10.2165/00128415-199304740-00030.

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&NA;. "Influenza virus vaccine." Reactions Weekly &NA;, no. 474 (October 1993): 8. http://dx.doi.org/10.2165/00128415-199304740-00035.

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