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Dissertations / Theses on the topic 'Infectious disease'

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1

DeMars, Kathleen R., and Nathaniel A. MD Justice. "Pneumonia masking the presentation of incomplete Kawasaki disease." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/76.

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Presentation: A 3 month-old male is referred for admission with a 2-day history of fever, having been diagnosed with pneumonia and prescribed a cephalosporin on the previous day. A blood culture obtained at that time is positive for coagulase negative Staphyloccocus. On exam, he is ill-appearing. He has bilateral conjunctivitis that spares the limbus, non-exudative pharyngitis, and a polymorphic truncal rash. There is no appreciable cervical lymphadenopathy or extremity involvement. A chest x-ray demonstrates a round infiltrate of the left upper lobe, and initial labs reveal a white blood coun
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2

陳奇志 and Qizhi Chen. "Analysis of infectious disease data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31239985.

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Chen, Qizhi. "Analysis of infectious disease data /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21841627.

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4

Ashraf, Shamaila. "Studies on infectious bursal disease virus." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1124124381.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xvi, 216 p.; also includes graphics (some col.). Includes bibliographical references (p. 180-216). Available online via OhioLINK's ETD Center
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5

Pressley, Meagan E. "Infectious Disease Models for the Zebrafish." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/PressleyME2004.pdf.

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6

Baillie, John Kenneth. "Statistical genetics in infectious disease susceptibility." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/17620.

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Death from infectious disease is common heritable, and in many cases a consequence of the host response, rather than direct effects of the pathogen. Since the host response in sepsis is orchestrated by the transmission of a variety of signals, both intra-cellular and inter-cellular, with which we have at least some capacity to intervene, it follows that it should be possible to prevent death through pharmaceutical modulation of inflammatory cascades. So far, it is not. The best candidate therapy for sepsis, activated protein C, failed to live up to initial promise and was ultimately withdrawn
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7

Ahmad, Iqra. "Infectious Disease: An agent-based simulation." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/honors/91.

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One of the primary reasons for studying infectious diseases is to improve control and ultimately eradicate the infection from the population (Keeling 2008). An agent base model was designed to observe the spread of disease and the effect of vaccination using the program known as StarLogo- TNG. Experiments were designed, not having a particular disease in mind, and simulations were run to determine the effects of different variables on the vaccination process of a certain population. Goals included observation of how infections spread and how vaccination plays a role in various situations such
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8

Mekaru, Sumiko Rachel. "Environmental risk factors in infectious diseases: studies in waterborne disease outbreaks, Ebola, and Lyme disease." Thesis, Boston University, 2013. https://hdl.handle.net/2144/11144.

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Thesis (Ph.D.)--Boston University<br>The resurgence of infectious diseases and global climate change's potential impact on them has refocused public health's attention on the environment's role in infectious disease. The studies in this dissertation utilize the increased availability of satellite image-derived data sets with fine temporal and geographic granularity and the expansion of epidemiologic methods to explore the relationship between the environment and infectious disease in three settings. The first study employed a novel study design and analytic methods to investigate the hypothes
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9

Rudd, Matthew Francis, and mikewood@deakin edu au. "Virulence determinants of infectious bursal disease virus." Deakin University. School of Biological and Chemical Sciences, 2003. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20050825.103742.

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The very virulent (vv) pathotype of infectious bursal disease virus (IBDV) has spread rapidly throughout Europe, Asia, and the Middle East. Although Australia is currently unaffected, there remains the potential for incursion of an exotic isolate. The aim of this study was to identify putative virulence determinants of IBDV to facilitate the development of improved diagnostic assays for detection and characterisation of vvIBDV isolates. Sequencing of Indonesian vvIBDV Tasik94 revealed a unique substitution [ A¨S222] in the hypervariable region (HVR) of viral protein (VP) VP2, which did not a
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10

Hofmann, Mathias. "Statistical Models for Infectious Disease Surveillance Counts." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-66012.

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11

Beadell, Jon Sumner. "Emerging infectious disease host and parasite perspectives /." College Park, Md. : University of Maryland, 2007. http://hdl.handle.net/1903/6744.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2007.<br>Thesis research directed by: Biology. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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12

Hon, Chung-chau. "Molecular evolution of infectious bursal disease virus." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B38821898.

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13

Hon, Chung-chau, and 韓鍾疇. "Molecular evolution of infectious bursal disease virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B38821898.

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14

Moody, Adrian John. "Mapping genetic resistance to infectious bursal disease." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326754.

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15

Majumder, Maimuna S. (Maimuna Shahnaz). "Modeling transmission heterogeneity for infectious disease outbreaks." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/120885.

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Thesis: Ph. D. in Engineering Systems, Massachusetts Institute of Technology, School of Engineering, Institute for Data, Systems, and Society, 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>The transmissibility of a given infectious disease is often described by its basic reproduction number (Ro) - namely, the average number of secondary infections caused by an index case in a fully susceptible population. Typical approaches to modeling transmission dynamics associated with infectious disease outbreaks frequently use Ro to produce deterministic case c
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16

Ghosh, Saurav. "News Analytics for Global Infectious Disease Surveillance." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/80574.

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Traditional disease surveillance can be augmented with a wide variety of open sources, such as online news media, twitter, blogs, and web search records. Rapidly increasing volumes of these open sources are proving to be extremely valuable resources in helping analyze, detect, and forecast outbreaks of infectious diseases, especially new diseases or diseases spreading to new regions. However, these sources are in general unstructured (noisy) and construction of surveillance tools ranging from real-time disease outbreak monitoring to construction of epidemiological line lists involves considera
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17

Rivers, Caitlin. "Modeling Emerging Infectious Diseases for Public Health Decision Support." Diss., Virginia Tech, 2015. http://hdl.handle.net/10919/52023.

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Emerging infectious diseases (EID) pose a serious threat to global public health. Computational epidemiology is a nascent subfield of public health that can provide insight into an outbreak in advance of traditional methodologies. Research in this dissertation will use fuse nontraditional, publicly available data sources with more traditional epidemiological data to build and parameterize models of emerging infectious diseases. These methods will be applied to avian influenza A (H7N9), Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV), and Ebola virus disease (EVD) outbreaks. This eff
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18

Appiah, Simon K. "Space-time statistical analysis of malaria morbidity incidence cases in Ghana: A geostatistical modelling approach." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2014. https://ro.ecu.edu.au/theses/1398.

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Malaria is one of the most prevalent and devastating health problems worldwide. It is a highly endemic disease in Ghana, which poses a major challenge to both the public health and socio-economic development of the country. Major factors accounting for this situation include variability in environmental conditions and lack of prevention services coupled with host of other socio-economic factors. Ghana’s National Malaria Control Programme (NMCP) risk assessment measures have been largely based on household surveys which provided inadequate data for accurate prediction of new incidence cases cou
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19

Alsan, Marcella Mousavi. "Infectious Diseases and Economic Development." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10321.

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This dissertation contains three essays analyzing how disease (particularly communicable disease) and development interact. The first chapter explores how TseTse-transmitted Trypanosomiasis influenced African development. The second essay seeks to understand why the HIV epidemic declined in Uganda. The third study investigates the effect of population health on foreign direct investment. In the first essay, I examine the effect of the TseTse fly on African historical development. African ethnicities in TseTse suitable areas are found to be more reliant on indigenous slavery, shifting agricultu
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20

Korobeinikov, Andrei. "Stability and bifurcation of deterministic infectious disease models." Thesis, University of Auckland, 2001. http://wwwlib.umi.com/dissertations/fullcit/3015611.

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Autonomous deterministic epidemiological models are known to be asymptotically stable. Asymptotic stability of these models contradicts observations. In this thesis we consider some factors which were suggested as able to destabilise the system. We consider discrete-time and continuous-time autonomous epidemiological models. We try to keep our models as simple as possible and investigate the impact of different factors on the system behaviour. Global methods of dynamical systems theory, especially the theory of bifurcations and the direct Lyapunov method are the main tools of our analysis.
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21

Davenport, Miles Philip. "Molecular analysis of HLA associations with infectious disease." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297073.

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22

羅文新 and Man-sun Law. "DNA vaccine against chicken infectious bursal disease virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31221221.

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23

Szeszko, Jeffrey Scott. "The genetics of immune-mediated and infectious disease." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611902.

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24

Rojek, Amanda. "Improving patient centred research during infectious disease outbreaks." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:8a53052f-9585-4709-a06e-15586826efce.

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Emerging infectious diseases (EIDs) constitute an important global health security problem. During EID outbreaks, patient centred research can play a significant role in informing evidence-based care for patients, in calibrating public health responses, and in directing effective policy and research. However, to date, this type of research has been limited in impact. This thesis sets out to improve the value of patient centred research in combating EID outbreaks. It provides a structured analysis of what has previously constrained efforts to rapidly accumulate high-quality evidence. It provide
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25

Nsubuga, Rebecca Namugabwe. "Statistical inference for infectious disease data of animals." Thesis, University of Edinburgh, 2004. http://hdl.handle.net/1842/30591.

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This thesis primarily explores parameter methods as applied to data generated from an experimental infection with foot and mouth disease (FMD) virus in sheep. Data were generated from two experiments involving four groups of sheep, housed under restricted mixing, where sheep in the initial group were inoculated with type O FMD virus. The aim of the analysis is to investigate the presence of any trend in the infection rate with increased generation. The infection process of FMD virus in sheep can be modelled using chain binomial models and generalized linear models. However, application of thes
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26

Natour, Mohammad Qasem. "Vaccination of chicks against infectious bursal disease virus /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487940665436333.

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27

Knoblich, Heidi Vivian. "Pathogenicity and immunogenicity of infectious bursal disease virus /." The Ohio State University, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488193665236897.

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28

Cathcart, Laura A. "Novice and expert comprehensive reasoning about infectious disease." College Park, Md.: University of Maryland, 2008. http://hdl.handle.net/1903/8590.

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Thesis (M.A.) -- University of Maryland, College Park, 2008.<br>Thesis research directed by: Dept. of Curriculum and Instruction. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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29

Law, Man-sun. "DNA vaccine against chicken infectious bursal disease virus /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20128393.

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30

Wombwell, Emma Louise. "Emerging infectious disease and the trade in amphibians." Thesis, University of Kent, 2014. https://kar.kent.ac.uk/48014/.

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Amphibians are the most threatened class of vertebrate, and rates of species decline and extinction far exceed those seen historically. Habitat loss, climate change, over-exploitation and emerging infectious disease have all been identified as threatening processes. The trade in amphibians has been implicated in over-exploitation through the harvesting of wild animals, and as an important pathway for the global spread of the fungal pathogen, Batrachochytrium dendrobatidis (Bd). However, there are no analyses of how Bd may spread through the trade chain. This thesis addresses this issue by (1)
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31

Ye, X., J. N. Van, F. M. Munoz, et al. "Noroviruses as a Cause of Diarrhea in Immunocompromised Pediatric Hematopoietic Stem Cell and Solid Organ Transplant Recipients." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/1490.

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Case reports describe significant norovirus gastroenteritis morbidity in immunocompromised patients. We evaluated norovirus pathogenesis in prospectively enrolled solid organ (SOT) and hematopoietic stem cell transplant (HSCT) patients with diarrhea who presented to Texas Children's Hospital and submitted stool for enteric testing. Noroviruses were detected by real-time reverse transcription polymerase chain reaction. Clinical outcomes of norovirus diarrhea and non-norovirus diarrhea patients, matched by transplanted organ type, were compared. Norovirus infection was identified in 25 (22%) of
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32

Elender, Frances. "The resurgence of tuberculosis in England and Wales." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323353.

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33

Tabrizi, Shervin. "Leveraging Genomic Signatures to Understand Human Disease: Applications in Infectious Disease and Cancer." Thesis, Harvard University, 2017. http://nrs.harvard.edu/urn-3:HUL.InstRepos:32676125.

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Genomics has been transformative to the study of human evolution and disease. With the dropping cost and increased availability of genome sequencing, it is now possible to probe the genetic mediators of human disease at an unprecedented level. My own research grew out of earlier work on the genomic signatures of natural selection in humans. As an undergraduate, I investigated the evidence for recent positive selection in large-scale genomic data, identifying pathways that appear to be targeted by evolution and prioritizing promising candidate variants for functional follow-up. In medical schoo
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34

Anroman, Gilda Marie. "Infectious disease in Philadelphia, 1690-1807 an ecological perspective /." College Park, Md. : University of Maryland, 2006. http://hdl.handle.net/1903/3700.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2006.<br>Thesis research directed by: American Studies. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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35

Donnelly, Ruairi. "Eco-evolutionary modelling of infectious disease and host resistance." Thesis, Heriot-Watt University, 2015. http://hdl.handle.net/10399/2914.

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In this work we take an evolutionary invasion analysis approach to modelling evolution and use it to describe the selection pressures underlying epidemiological traits in natural host populations harboring endemic infections. Throughout this work a logistic form for host-birth rate allows for disease dependent population dynamics so that the detrimental e ects of infection can be modelled and we also consider the more neglected detrimental e ect whereby infection is linked to infertility. To begin with we give a theoretical introduction to the framework of adaptive dynamics and illustrate it t
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36

Marmara, Vincent Anthony. "Prediction of Infectious Disease outbreaks based on limited information." Thesis, University of Stirling, 2016. http://hdl.handle.net/1893/24624.

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The last two decades have seen several large-scale epidemics of international impact, including human, animal and plant epidemics. Policy makers face health challenges that require epidemic predictions based on limited information. There is therefore a pressing need to construct models that allow us to frame all available information to predict an emerging outbreak and to control it in a timely manner. The aim of this thesis is to develop an early-warning modelling approach that can predict emerging disease outbreaks. Based on Bayesian techniques ideally suited to combine information from diff
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37

Licata, Matthew J. "The efficacy of combined infectious bronchitis/Newcastle disease vaccines." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 112 p, 2007. http://proquest.umi.com/pqdlink?did=1253510101&Fmt=7&clientId=79356&RQT=309&VName=PQD.

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38

Howard, Sally Claire. "Statistical estimation of epidemiological parameters relating to infectious disease." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365804.

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39

Xue, Chunyi, and 薛春宜. "Molecular characterization of infectious bursal disease virus (IBDV) receptor." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31246187.

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40

Wark, Kim Louise. "Expression and processing of infectious bursal disease virus proteins." Thesis, University of Hertfordshire, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323651.

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41

Gog, Julia Rose. "The dynamics of multiple strains of an infectious disease." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619522.

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42

Hansen, Victoria Lee. "Recent Infectious Disease Mortality Trends in the United States." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/594558.

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Importance: Infectious diseases present an ever-changing threat to public health. Analysis of pathogen-linked mortality trends is elucidatory to infectious disease burden. Objective: To describe major shifts in United States infectious disease mortality trends from 1900-2013 with emphasis on recent changes for1980-2013. Design: Ecological study of infectious disease mortality in the United States. Setting: Infectious disease deaths were summed from Vital Statistic Reports from 1900-1967. Infectious disease deaths from 1968-2013 were extracted from the Centers for Disease Control and Prevention
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Bingham, Adrienna N. "Controlling Infectious Disease: Prevention and Intervention Through Multiscale Models." W&M ScholarWorks, 2019. https://scholarworks.wm.edu/etd/1582642581.

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Controlling infectious disease spread and preventing disease onset are ongoing challenges, especially in the presence of newly emerging diseases. While vaccines have successfully eradicated smallpox and reduced occurrence of many diseases, there still exists challenges such as fear of vaccination, the cost and difficulty of transporting vaccines, and the ability of attenuated viruses to evolve, leading to instances such as vaccine derived poliovirus. Antibiotic resistance due to mistreatment of antibiotics and quickly evolving bacteria contributes to the difficulty of eradicating diseases such
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44

Venkatachalam, Sangeeta. "Modeling Infectious Disease Spread Using Global Stochastic Field Simulation." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5335/.

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Susceptibles-infectives-removals (SIR) and its derivatives are the classic mathematical models for the study of infectious diseases in epidemiology. In order to model and simulate epidemics of an infectious disease, a global stochastic field simulation paradigm (GSFS) is proposed, which incorporates geographic and demographic based interactions. The interaction measure between regions is a function of population density and geographical distance, and has been extended to include demographic and migratory constraints. The progression of diseases using GSFS is analyzed, and similar behavior to t
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45

Vallet, Victor Jay. "Infection and Infectious Disease US Military Medicine in the Pacific Theater of Operations during WWII." Thesis, The University of Arizona, 2009. http://hdl.handle.net/10150/193017.

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46

Brierley, Liam. "The ecology of emerging diseases : virulence and transmissibility of human RNA viruses." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/22067.

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Emerging infectious diseases continue to represent serious threats to global human health. Novel zoonotic pathogens are continually being recognised, and some ultimately cause significant disease burdens and extensive epidemics. Research and public health initiatives often face emerging pathogens with limited knowledge and resources. Inferences from empirical modelling have begun to uncover the factors determining cross-species transmission and emergence in humans, and subsequently guide risk assessments. However, the dynamics of virulence and transmissibility during the process of emergence a
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47

McInnis, Leah Russell. "Law and the control of infectious disease during extraordinary emergencies." Thesis, Lancaster University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404255.

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48

巫志偉 and Chi-wai Mo. "Prevention and therapy of infectious bursal disease by molecular approaches." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B30253329.

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Yeung, Wing-shing, and 楊永成。. "Development of a subunit vaccine against infectious bursal disease virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31222055.

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Prakash, Manyu. "Leukocytes in the cervical epithelium in health and infectious disease." Thesis, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404575.

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