Academic literature on the topic 'Infection'

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Journal articles on the topic "Infection"

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Epperla, Narendranath, Mirela Anghelina, Qiuhong Zhao, Akwasi Agyeman, James S. Blachly, Kerry A. Rogers, Gerard Lozanski, Christopher C. Oakes, Michael R. Grever, and Leslie Andritsos. "Infection at the Time of Initial Therapy for Hairy Cell Leukemia Is Associated with Inferior Time to Next Treatment." Blood 132, Supplement 1 (November 29, 2018): 2305. http://dx.doi.org/10.1182/blood-2018-99-119951.

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Abstract Introduction: Hairy Cell Leukemia (HCL) is a rare, chronic hematological malignancy that makes up approximately 2% of all leukemias. HCL patients are at a markedly increased risk for infection related to a combination of disease-related and treatment-related immunosuppression which has been well described in the literature. However, the significance of infection prior to initiation of HCL therapy and its impact on the subsequent selection of HCL treatment, or outcomes, is not well described. Using the HCL patient data registry, we report here the impact of antecedent infection on the treatment patterns and outcomes of HCL patients. Methods: We evaluated adult (≥18 years) patients with HCL who had information regarding antecedent infections and subsequent HCL treatment during 1984-2018. The primary endpoint was progression-free survival (PFS-1). Secondary endpoint included time to next treatment (TTNT). PFS-1 was measured from the date of first HCL treatment to date of progression/death or last follow-up. TTNT was defined as the time from first HCL treatment to initiation of second HCL treatment. The study population was stratified into 3 groups based on the presence or absence of antecedent infections: no infection prior to first HCL treatment (no infection group), infection within 30 days prior to first HCL treatment (infection1 group) and infection >30 days prior to first HCL treatment (infection2 group). Fisher's exact test or Kruskal-Wallis test was used to compare the characteristics among the no infection and infection groups and the Cox proportional hazard model was used to evaluate the association with PFS-1 and TTNT. Results: A total of 205 HCL patients who had information regarding antecedent infections and subsequent HCL treatment were eligible for the study. Among these, 144 (70%) belonged to the no infection group, while 26 patients (13%) belonged to infection1 group and 35 (17%) to infection2 group. Patient characteristics are shown in Table 1 with a breakdown between the three groups. The majority of the patients were Caucasian with a male preponderance and had classic HCL. The patients in the infection1 group had a lower median WBC (K/uL) (1.9 vs 3.1 vs 2.9), particularly the absolute neutrophil count (K/uL) (0.4 vs 0.7 vs 0.8) and significantly lower median hemoglobin (gm%) (10.1 vs 12.2 vs 12.4) relative to the no infection and infection2 groups, respectively (p=0.01). Similarly, a greater proportion of patients in the infection1 group had significant comorbidities (including pulmonary, gastrointestinal and hepatic disease) relative to no infection and infection2 groups as shown in Table 1. The majority of patients received purine nucleoside analogs as their first HCL treatment (no infection group=92%, infection1 group=85%, infection2 group=94%). The median PFS-1 (in years) was better in the no infection group compared to the infection1 group but was not statistically significant (17.0 [95% CI=7.9-not reached (NR)] vs 8.8 [95% CI=4.2-NR], respectively, p=0.98, Figure 1). However, the median TTNT (in years) was significantly longer for HCL patients with no infection versus the infection1 group (6.3 [95% CI=5.4-7.8] vs 3.6 [95% CI=0.7-NR], respectively, p=0.001, Figure 1). On subgroup analysis, relative to the no infection group, median PFS-1 (in years) was not significantly different in infection1 group treated with Pentostatin (10.7 [95% CI=3.53-NR] vs NR [95% CI=1.38-NR], respectively, p=0.43), however, the median PFS-1 (in years) was shorter in the infection1 group treated with Cladribine (17.0 [95% CI=7.67-NR] vs 4.0 [95% CI=2.00-NR], respectively), although not reaching statistical significance (p=0.09) probably due to small sample size. Conclusion: In this large series of HCL patients who received treatment, we show that the patients who had infections at the time of HCL treatment have a significantly shorter TTNT. The reasons for this are unclear but may indicate that patients were unable to receive treatment in a timely manner because of the infection, or were unable to complete treatment because of complications. The significant difference in hemoglobin between the infection1 and other groups indicates the possibility that these patients had more advanced HCL at the time of diagnosis. These findings indicate the potential long term negative impact of infections in patients who need treatment for HCL and reinforce the need for careful management in this setting. Disclosures Lozanski: Beckman: Research Funding; Coulter: Research Funding; Stem Line: Research Funding; Genentech: Research Funding; Novartis: Research Funding; BI: Research Funding. Andritsos:HCLF: Membership on an entity's Board of Directors or advisory committees; AstraZeneca: Consultancy.
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Jayasree, T., and Mustafa Afzal. "Implementation of Infection Control Practices to Manage Hospital Acquired Infections." Journal of Pure and Applied Microbiology 13, no. 1 (March 31, 2019): 591–97. http://dx.doi.org/10.22207/jpam.13.1.68.

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Scendoni, Roberto, Emanuele Bury, Isabella Lima Arrais Ribeiro, Mariano Cingolani, Roberto Cameriere, Anna De Benedictis, and Francesco De Micco. "Leading Pathogens Involved in Co-Infection and Super-Infection with COVID-19: Forensic Medicine Considerations after a Systematic Review and Meta-Analysis." Pathogens 12, no. 5 (April 27, 2023): 646. http://dx.doi.org/10.3390/pathogens12050646.

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The COVID-19 pandemic raised concerns about the potential for co-infection or over-infection with other respiratory infections, as they can complicate the diagnosis, treatment and prognosis of the disease. This is also a challenge for forensic pathologists, who may come across cases where the presence of co-infection or over-infection is suspected or confirmed, and it is important that they take this into account when determining the cause of death. The aim of this systematic review is to analyse the prevalence of each specific pathogen co-infecting or over-infecting patients with SARS-CoV-2 infection. In total, 575 studies were selected from the Scopus and Pub-Med online databases and 8 studies were included in a meta-analysis. Male gender, advanced age and nursing home care are risk factors associated with the development of co-infection, whereas age, tachypnoea, hypoxaemia and bacterial infection are predictors of mortality. Overall, however, having a SARS-CoV-2 infection does not represent a real risk for the development of co-infections/super-infections.
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Newsom, William. "Wound Infection." Infection Control & Hospital Epidemiology 7, S2 (February 1986): 109–10. http://dx.doi.org/10.1017/s0195941700065590.

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Any consideration of infection following clean surgery, particularly cardiothoracic must include both exogenous and endogenous sources. The MRC Study on Hip Surgery presents a particular challenge. Although uncontrolled antibiotic prophylaxis reduced the infection rate almost as well as a laminar flow operating theater, further analysis of the data correlated the incidence of infection with the theater air counts and more significantly considered the sources of Staphylococcus aureus infections. Data on swabs from patient and theater staff at the time of surgery were available for 14 of the 28 patients who subsequently developed deep infections with S. aureus. Overall 25% of patients and 33% of staff were carriers. Bacteriophage typing revealed that 2 patients, 2 surgeons and 7 theater staff carried the infecting type at the time of the surgery. In two instances there was no correlation and in the last a member of the surgical staff on leave at the time carried the relevant strain. This at least provides a clue that exogenous infection can be important, and justifies attempts to clean the environment as well as the patient.
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Glynn, Judith R., and Adrian C. Jones. "Atypical respiratory infections, including chlamydia TWAR infection and legionella infection." Current Opinion in Infectious Diseases 3, no. 2 (April 1990): 169–75. http://dx.doi.org/10.1097/00001432-199004000-00004.

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Breathnach, Aodhán S. "Nosocomial infections and infection control." Medicine 41, no. 11 (November 2013): 649–53. http://dx.doi.org/10.1016/j.mpmed.2013.08.010.

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Jenkins, David R. "Nosocomial infections and infection control." Medicine 45, no. 10 (October 2017): 629–33. http://dx.doi.org/10.1016/j.mpmed.2017.07.005.

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Bergogne-Bérézin, E. "Acinetobacter infections: Unusual infection sites." Antibiotiques 10, no. 2 (May 2008): 81–87. http://dx.doi.org/10.1016/j.antib.2007.12.009.

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Avila, Vicente, and Daniel Rissi. "Ulcerative dermatitis due to feline infectious peritonitis virus infection in a cat." Brazilian Journal of Veterinary Pathology 13, no. 1 (March 31, 2020): 48–50. http://dx.doi.org/10.24070/bjvp.1983-0246.v13i1p48-50.

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Simon, Tamara D., Matthew P. Kronman, Kathryn B. Whitlock, Samuel R. Browd, Richard Holubkov, John R. W. Kestle, Abhaya V. Kulkarni, et al. "Patient and Treatment Characteristics by Infecting Organism in Cerebrospinal Fluid Shunt Infection." Journal of the Pediatric Infectious Diseases Society 8, no. 3 (May 15, 2018): 235–43. http://dx.doi.org/10.1093/jpids/piy035.

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Abstract Background Previous studies of cerebrospinal fluid (CSF) shunt infection treatment have been limited in size and unable to compare patient and treatment characteristics by infecting organism. Our objective was to describe variation in patient and treatment characteristics for children with first CSF shunt infection, stratified by infecting organism subgroups outlined in the 2017 Infectious Disease Society of America’s (IDSA) guidelines. Methods We studied a prospective cohort of children <18 years of age undergoing treatment for first CSF shunt infection at one of 7 Hydrocephalus Clinical Research Network hospitals from April 2008 to December 2012. Differences between infecting organism subgroups were described using univariate analyses and Fisher’s exact tests. Results There were 145 children whose infections were diagnosed by CSF culture and addressed by IDSA guidelines, including 47 with Staphylococcus aureus, 52 with coagulase-negative Staphylococcus, 37 with Gram-negative bacilli, and 9 with Propionibacterium acnes. No differences in many patient and treatment characteristics were seen between infecting organism subgroups, including age at initial shunt, gender, race, insurance, indication for shunt, gastrostomy, tracheostomy, ultrasound, and/or endoscope use at all surgeries before infection, or numbers of revisions before infection. A larger proportion of infections were caused by Gram-negative bacilli when antibiotic-impregnated catheters were used at initial shunt placement (12 of 23, 52%) and/or subsequent revisions (11 of 23, 48%) compared with all other infections (9 of 68 [13%] and 13 of 68 [19%], respectively). No differences in reinfection were observed between infecting organism subgroups. Conclusions The organism profile encountered at infection differs when antibiotic-impregnated catheters are used, with a higher proportion of Gram-negative bacilli. This warrants further investigation given increasing adoption of antibiotic-impregnated catheters.
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Dissertations / Theses on the topic "Infection"

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Чемич, Оксана Миколаївна, Оксана Николаевна Чемич, Oksana Mykolaivna Chemych, Я. Л. Кравцова, and А. А. Олефір. "Structure of opportunistic infections in patients with HIV- infection." Thesis, Sumy State University, 2018. http://essuir.sumdu.edu.ua/handle/123456789/74893.

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Діагностика першої та другої стадій ВІЛ-інфекції низька. Опортуністичні інфекції та супутні захворювання посилюють перебіг ВІЛ-інфекції. Найбільш поширеною опортуністичною інфекцією є кандидоз ротоглотки. У структурі супутньої патології переважають хронічні вірусні гепатити С і метаболічна кардіоміопатія.
Диагностика первой и второй стадии ВИЧ-инфекции невысока. Оппортунистические инфекции и сопутствующие заболевания обостряют течение ВИЧ-инфекции. Наиболее распространенной оппортунистической инфекцией является кандидоз ротоглотки. Хронический вирусный гепатит С и метаболическая кардиомиопатия преобладают в структуре сопутствующей патологии.
Diagnosis of the first and second stages of HIV-infection is low. Opportunistic infections and concomitant illnesses aggravate the course of HIV-infection. The most common opportunistic infection is oropharyngeal candidiasis. Chronic viral hepatitis C and metabolic cardiomyopathy are predominate in the structure of concomitant pathology.
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Chung, Moonsik. "Infection /." Link to online version, 2006. https://ritdml.rit.edu/dspace/handle/1850/2291.

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Thesis (M.F.A.)--Rochester Institute of Technology, 2006.
Typescript. Film produced by Damul Films. Director, Moonsik Chung. Cast: Jonathan Flanigan, Ashley St. John-Yantz, Greg Petralis, Jesse Knight. Co-writer, Oreathia C. Smith.
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Corvellec-Rudelli, Anne. "Les infections néo-natales." Bordeaux 2, 1989. http://www.theses.fr/1989BOR23061.

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Richard, Patrick. "L'infection en réanimation : étude prospective." Montpellier 1, 1990. http://www.theses.fr/1990MON11221.

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Nguyen, Patrick Bouaziz Hervé. "Etude de l'intérêt et influence de la décontamination digestive sélective chez le patient polytraumatisé ventilé en réanimation chirurgicale." [S.l.] : [s.n.], 2001. http://www.scd.uhp-nancy.fr/docnum/SCDMED_T_2001_NGUYEN_PATRICK.pdf.

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Walzl, Gerhard. "The influence of infection history on the immunopathology of unrelated infections." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405807.

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Bettridge, Judy. "The epidemiology and ecology of infectious diseases in Ethiopian village chickens and the role of co-infection in infection risk." Thesis, University of Liverpool, 2014. http://livrepository.liverpool.ac.uk/2004959/.

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The scavenging village chicken is important to millions of smallholders in Ethiopia, as in other less-economically developed countries, for its contribution to the economic, nutritional and social well-being of farmers, especially women and children. Infectious diseases are frequently cited as the greatest constraint to village chicken production, and in Ethiopia, most mortality is attributed to seasonal outbreaks of Newcastle disease (ND). This study conducted four cross-sectional surveys over an 18-month period in two geographically distinct regions of Ethiopia, to examine a range of bacterial, viral and parasitic infections in randomly-selected village chickens, and to look at their 6-month survival rate. The two chicken populations of the different regions were found to be different in terms of their population dynamics and phenotypic characteristics, and these may be driven by farmer demands, which are dictated by the local economic and cultural value placed on specific qualities in the chickens. Over the course of the study, no large outbreaks were observed in the eight villages which took part in the study, and only 9 out of 1280 birds (0.7%) were found to be serologically positive for ND. However, even in the absence of large outbreaks, around 20% of the birds in the study were reported to have died of disease within the 6-month follow-up period, and a further 13% lost to predation. Both location and seasonal variation influenced a bird’s fate, as did farmer decisions, such as choosing birds with specific characteristics to sell or eat. Rather than large outbreaks, the rainy season appeared to be associated with increased small-scale losses, and a variety of signs were described, suggesting several pathogens may be involved. No single infection measured at the time of sampling was a good predictor of subsequent death from disease; instead different pathogens appeared to be important in each region, and reduced the probability of survival through a variety of mechanisms. Positive correlations between Pasteurella and Salmonella, and between Marek’s disease and parasitic diseases were identified, but fewer birds than expected were identified with pathogens from both these groups, perhaps suggesting a decreased chance of survival for co-infected birds. Strong seasonal variation in prevalence was not observed for any of the infections in the study, suggesting that seasonal rises in disease mortality are unlikely to be attributable to a single infection, but other factors may play a role, including an increased probability of co-infection. This makes it difficult to prioritise control strategies for individual diseases; instead development programmes may find broad-based strategies, such as improving hygiene and chick management may be more beneficial to minimise the small-scale losses. Programmes also need to be tailored to local needs rather than assuming a blanket strategy will work equally well for all farmers or regions. Any development strategies to control single diseases should consider potential impacts on non-target infections, due to the existence of multiple interactions between pathogens in this system.
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Berthelot, Philippe. "Exploration endoscopique et instrumentation thérapeutique comme sources d'infection respiratoire nosocomiale." Saint-Etienne, 1993. http://www.theses.fr/1993STET6411.

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Phan, Quang Tien. "Innate immune response to tissue-specific infection : notochord infection in the zebrafish embryo." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT082/document.

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Lors des infections bactériennes, selon les tissus infectés, et selon la nature des pathogènes, l’organisme répond en mobilisant différents acteurs. Nous avons décidé d’utiliser le modèle du zebrafish ou Danio rério pour étudier la réponse immunitaire innée dans les situations d’infection bactérienne où les phagocytes professionnels ne peuvent pas venir au contact direct des bactéries. Pour cela, j’ai développé un modèle d’infection de la notochorde del’embryon de zebrafish. Lors de l’injection des bactéries dans ce compartiment, les bactéries se retrouvent protégées par une épaisse gaine de collagènes que les phagocytes ne peuvent pas pénétrer. Alors que les mycobactéries,protégées par la gaine de collagène ne sont pas détectées par les phagocytes, les bactéries E. coli sont immédiatement détectées ce qui déclenche une importante inflammation locale autour de la notochorde. Alors que les bactéries E. coli, bien qu’inaccessibles à la phagocytose sont éliminées dans les première 24 heures qui suivent l’injection, l’inflammation dure plusieurs jours.J’ai étudié les mécanismes qui conduisent à cette inflammation persistante et ses conséquences à long terme sur le développement du poisson. J’ai montré le rôle central de la cytokine IL1b dans ce processus, et j’ai développé une lignée transgénique qui permet d’étudier l’induction de cette cytokine in vivo chez le poisson.J’ai ensuite étudié le rôle des deux principales populations de phagocytes dans l’élimination des bactéries E coli. J’ai montré que les macrophages ne sont pas impliqués dans la disparition des bactéries alors que les neutrophiles, bien qu’incapable de pénétrer à l’intérieur de la gaine de collagène sont nécessaires à l’élimination des bactéries.J’ai ensuite montré que la myelopéroxidase et le monoxyde d’azote ne sont pas impliqués dans l’élimination des bactéries alors que les espèces réactives de l’oxygène produites par les neutrophiles sont nécessaires pour éradiquer l’infection
In bacterial infections, according to the infected tissue and the nature of pathogens, the body responds by mobilizing various actors. I decided to use zebrafish or Danio rerio model to study the innate immune response to bacterial infection in the situations that professional phagocytes cannot come in direct contact with the bacteria. For this, I developed a model of infection in the notochord of zebrafish embryo. Upon injection of bacteria in this compartment, the microbes find themselves protected by the thick collagensheath where the phagocytes cannot penetrate. While mycobacteria are not detected by phagocytes; E. coli bacteria are sensed and a significant local inflammation around the notochord is mounted. The E. coli, although inaccessible to phagocytosis are eliminated within the first 24 hours after injection, the inflammation lasts several days.I studied the mechanisms that lead to this persistent inflammation and its long term consequences on the development of the fish. I showed the central role of the cytokine IL1B in this process, and I developed a transgenic line that allows studying in vivo the induction of this cytokine in fish.I then studied the roles of the two main populations of phagocytes in the elimination of E. coli. I revealed that macrophages are not involved in the removal of bacteria but neutrophils, although unable to penetrate inside the collagen casing, are necessary for the bacterial elimination. I also confirmed that myeloperoxidase and nitrogen monoxide are not involved in the removal of bacteria, rather the reactive oxygen species produced by neutrophils are needed to eradicate the infection
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Tscherning, Charlotte. "Déterminants biologiques et génétiques du VIH-1 et rôle du placenta dans la transmission materno-foetale." Lyon 1, 1998. http://www.theses.fr/1998LYO1T187.

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Books on the topic "Infection"

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Escobar, Mario R., and John P. Utz, eds. Infection. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-3748-3.

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Emond, R. T. D. Infection. 2nd ed. Oxford: Blackwell Scientific, 1989.

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ed, Escobar Mario R., and Utz, John P., 1922- ed., eds. Infection. New York: Plenum, 1988.

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Ziady, Laura. Prevent and control infection: Application made easy. Cape Town: Juta, 2004.

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1959-, Davies Huw, ed. Infection and immunity. London: Taylor & Francis, 1999.

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Christine, Bechtel-Boenning, Boland Mary, and Grady Christine, eds. HIV infection. Perinatally transmitted HIV infection. Philadelphia: W.B. Saunders Co., 1996.

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Siemens, Heide H. Infection & infections: Medical subject research analysis with bibliography. Washington, D.C: ABBE Publishers Association, 1985.

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Philpott-Howard, J. Hospital infection control: Policies and practical procedures. London: W.B. Saunders, 1994.

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McGuckin, Maryanne. The patient survival guide: 8 simple solutions to prevent hospital- and healthcare-associated infections. New York: DemosHealth, 2012.

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Coathup, Melanie, ed. Musculoskeletal Infection. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-83251-3.

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Book chapters on the topic "Infection"

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Israel, Ora, Enrique Estrada-Lobato, and Thomas Neil Pascual. "Infection and Inflammation Imaging." In A Practical Guide for Pediatric Nuclear Medicine, 183–98. Berlin, Heidelberg: Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-67631-8_11.

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AbstractMost commonly infectious processes in children involve the peripheral skeleton, lungs, kidneys, brain, and heart. Pediatric infections are usually of viral and bacterial origins. Fungal etiology can be found, mainly in children with immunodeficiency. Neonates also have immature immunity and are prone to infections with a less favorable prognosis. Conventional techniques used to evaluate infectious and inflammatory processes in children provide high-resolution images but are limited since only insignificant findings are seen in early disease stages and the differential diagnosis with coexisting pathologies and/or post-treatment changes is challenging. Nuclear Medicine procedures play an important role in diagnosing and monitoring pediatric infections, and inflammatory and granulomatous diseases. Several SPECT radiotracers used in the past for functional imaging of infection and inflammatory processes, such as 67Gallium citrate and 111In-labelled WBCs are not being used anymore routinely in pediatric patients and only rarely in adults, mainly in centers with limited or no access to 99mTc-labelled leukocytes (WBCs) and PET imaging. The value of Nuclear Medicine tests has increased with the implementation of hybrid SPECT/CT, PET/CT, and PET/MRI imaging.
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Du, Xiaodan, Shuang Ding, Jian Wang, Chunhui Jiang, Jun Liu, Ling Wu, Hanqiu Liu, Weiwei Wang, Dan Zhang, and Jun Lu. "Entomophila Infection-Related Intracranial Infections." In Radiology of Infectious and Inflammatory Diseases - Volume 1, 75–94. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0039-8_8.

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Howard, Jo, and Paul Telfer. "Infection and Infection Prophylaxis." In Sickle Cell Disease in Clinical Practice, 173–79. London: Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-2473-3_12.

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Rogers, Rosemary, Jane Salvage, and Roger Cowell. "Infection and infection risks." In Nurses at Risk, 142–76. London: Macmillan Education UK, 1999. http://dx.doi.org/10.1007/978-1-349-14803-5_7.

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Heppner, John B., D. G. Boucias, J. C. Pendland, Andrei Sourakov, Timothy Ebert, Roger Downer, Kun Yan Zhu, et al. "Infection." In Encyclopedia of Entomology, 1925. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_1524.

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Citerio, G., C. Giussani, Hugo Sax, Didier Pittet, Xiaoyan Wen, John A. Kellum, Angela M. Mills, et al. "Infection." In Encyclopedia of Intensive Care Medicine, 1213. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_3165.

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Goldenberg, Robert L., and Elizabeth M. McClure. "Infection." In Stillbirth: Prediction, Prevention and Management, 82–99. Oxford, UK: Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444398038.ch5.

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Kim, Bongcheol, Seungmin Oh, and Wonsug Jung. "Infection." In The Art and Science of Thread Lifting, 261–62. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-0614-3_47.

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Hilton, Rachel, and Martin W. Drage. "Infection." In Handbook of Renal and Pancreatic Transplantation, 335–79. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781118305294.ch21.

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Olszewski, Waldemar L. "Infection." In Lymphedema, 207–16. London: Springer London, 2011. http://dx.doi.org/10.1007/978-0-85729-567-5_25.

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Conference papers on the topic "Infection"

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Mitkovskaya, O. A. "Hepatitis and allergic process – immune interaction." In General question of world science. НИЦ "LJournal", 2023. http://dx.doi.org/10.18411/gqws-10-2023-04.

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Studies of the interaction effect in patients with infectious hepatitis, other infections with subsequent development of allergic inflammation (allergic nosological entities, atopic form of bronchial asthma) were going for several years. In clinical and epidemiological studies, two types of the effect of infection on immunity were studied: inhibition of the development of allergic diseases or enhancement of the mechanism of allergy progression. An inverse correlation was revealed between bacterial infections and atopic mechanisms of development of allergic diseases and bronchial asthma
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Kurćubić, Vladimir, Marko Dmitrić, Saša Živković, and Miloš Petrović. "Severe adverse impact of bovine viral diarrhea on cattle production: A comprehensive approach to control." In Zbornik radova 26. medunarodni kongres Mediteranske federacije za zdravlje i produkciju preživara - FeMeSPRum. Poljoprivredni fakultet Novi Sad, 2024. http://dx.doi.org/10.5937/femesprumns24020k.

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Bovine viral diarrhea (BVD) is caused by a pestivirus known as BVDV and is one of the most important infectious diseases of cattle, with a huge economic impact worldwide. The most important source of infection are persistently infected (PI) and diseased cattle. In addition to cattle infection, BVDV infection has been diagnosed in sheep, goats, pigs and wild ruminants (roe deer, deer, bison), as reservoirs of the virus and sources of infection in cattle herds. The consequences of BVDV infections are abortions in pregnant animals, poor female conception, mummification and congenital malformations of fetuses, respiratory problems, transplacental infections and fetal death, neonatal and postnatal mortality, mucosal diseases, slowed growth and poorer performance of surviving animals. Hemorrhagic syndrome (with thrombocytopenia and hemorrhage) is caused exclusively by non-cytopathogenic (NCP) BVDV genotype 2, i.e. virulent strains. The basis of the control program is the prevention of intrauterine infection by identifying and removing PI animals from the cattle herd. The high prevalence of BVDV in cattle worldwide and in Serbia is a danger and causes extremely high economic losses, preventing international trade in breeding and fattening cattle with EU countries, primarily due to uneven approaches or lack of control programs. There are suggestions that the control of the disease in Serbia could be based on a voluntary BVDV eradication program at the herd level, based on four phases, which includes frequent diagnostic tests, removal of PI animals from the herd and introduction of strict biosecurity measures. Certification and register of herds with BVDV free status could be done through the Veterinary Administration.
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Jang, Beakcheol, Miran Lee, Myeong hwi Kim, Hyun jung Kim, Hoon Yoo, and Jong Wook Kim. "Infectious disease infection index information system." In 2019 IEEE International Conference on Consumer Electronics (ICCE). IEEE, 2019. http://dx.doi.org/10.1109/icce.2019.8661844.

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Huang, Hao, Keqi Han, Beicheng Xu, and Ting Gan. "Reconstructing Diffusion Networks from Incomplete Data." In Thirty-First International Joint Conference on Artificial Intelligence {IJCAI-22}. California: International Joint Conferences on Artificial Intelligence Organization, 2022. http://dx.doi.org/10.24963/ijcai.2022/428.

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To reconstruct the topology of a diffusion network, existing approaches customarily demand not only eventual infection statuses of nodes, but also the exact times when infections occur. In real-world settings, such as the spread of epidemics, tracing the exact infection times is often infeasible; even obtaining the eventual infection statuses of all nodes is a challenging task. In this work, we study topology reconstruction of a diffusion network with incomplete observations of the node infection statuses. To this end, we iteratively infer the network topology based on observed infection statuses and estimated values for unobserved infection statuses by investigating the correlation of node infections, and learn the most probable probabilities of the infection propagations among nodes w.r.t. current inferred topology, as well as the corresponding probability distribution of each unobserved infection status, which in turn helps update the estimate of unobserved data. Extensive experimental results on both synthetic and real-world networks verify the effectiveness and efficiency of our approach.
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Akzholtoeva, Aizharkyn A., Gulmira A. Dzhumalieva, Anna V. Lubimova, Gulzat Zhanadilovna Zhanadilova, and Davranbek kyzy Meerim. "Assessment of the state of infection control in medical and preventive organizations in Osh region." In Innovations in Medical Science and Education. Dela Press Publishing House, 2022. http://dx.doi.org/10.56199/dpcsms.iauj7163.

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This article presents the results on the state of infection control in medical and preventive organizations in the Osh region. Report on the incidence of infections associated with medical care and infections in the field of surgical interventions of 2021 years. The research was conducted in 8 medical and preventive organizations in the districts of Osh region and in the city of Osh using the "Scorecard of infection control in healthcare organizations" including 64 criteria (sanitary and hygienic requirements, safety of medical procedures, compliance with disinfection, sterilization of surgical instruments and materials, administrative measures etc.), for the prevention of infections associated with the provision of medical care and infection in the field of surgical interventions. The assessment of the state of infection control was carried out by calculating the numerical expression of the percentage between the existing fulfillment of infection control requirements according to the data on the registration of the incidence. During the assessment, the main sanitary and hygienic directions for the prevention of diseases of infections associated with the provision of medical care and infections in the field of surgical interventions were identified.
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Vasilevich, F. I., S. A. Shemyakova, and N. V. Esaulova. "VETERINARY AND MEDICAL SIGNIFICANCE OF HORSEFLY (TABANIDAE). REVIEW." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”, 2023. http://dx.doi.org/10.31016/978-5-6048555-6-0.2023.24.133-137.

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The article provides information on the harmful effect of horseflies (Diptera, Tabanidae) as a midge component and a vector (carrier) transmitting pathogens of infectious and parasitic diseases including zoonosis. Horseflies are harmful to animals and humans in places of their abundance. Horseflies cause significant economic losses to livestock. With an intense attack of horseflies, individual areas of the skin of animals represent a continuous bleeding surface. Horsefly saliva inserted into a wound at the time of the bite is very toxic and allergenic causing a local inflammatory process and general intoxication of the body. The insects are of particular danger as vectors transmitting pathogens of animals and humans. The role of horseflies in the transmission of tularemia in natural foci of this infection has been proven. The sources of horsefly infection are primarily various small mammals including water rats. Horseflies are equally important as carriers of the anthrax pathogen. Causative agents of Coxiella burnetti infection, blackleg, pasteurellosis, and other infections have been isolated from horseflies. Horseflies are involved in the transmission of Trypanosoma evansi in horses and camels, anaplasmosis in cattle, Theileria cervi in reindeer, and equine infectious anemia virus.
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Sijamhodžič, Aida, and Alenka Žvikart. "EPIDEMIOLOGICAL SURVEILLANCE OF SURGICAL WOUND INFECTIONS AS A LEADING INDICATOR OF THE QUALITY OF POST-SURGICAL CARE FOR CHILDREN." In 14. kongres zdravstvene in babiške nege Slovenije,11. in 12. maj 2023, Kongresni center Brdo, Brdo pri Kranju. Zbornica zdravstvene in babiške nege Slovenije - Zveza strokovnih društev medicinskih sester, babic in zdravstvenih tehnikov Slovenije, 2023. http://dx.doi.org/10.14528/asae9754.18.

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Introduction: The European Centre for Disease Prevention and Control (ECDC) ranks surgical wound infection among the most common hospital infections, which, as a result, can prolong the hospitalization time, requires additional surgical interventions, treatments and intensive therapy, or even increases mortality. Implementation of epidemiological monitoring reduces the incidence rate of surgical wound infections, and monitoring the incidence rate enables assessment of the quality of medical care. After increasing importance of verification levels of quality of medical care, the University Clinical Centre Department of Paediatric Surgery decided for the project of systematic prospective monitoring of surgical wound infections in children. Methods: A quantitative research method was used with a prospective and retrospective data analysis for certain interventions. The research project was divided into several phases. The research sample included children at the Department of Paediatric Surgery for planned and emergency surgical interventions. The children were monitored for 30 days after the intervention (in the case of an implant for 90 days). The goal of the research was to establish clinical practice of monitoring surgical wound infections in children, and the introduction of appropriate preventive measures for reducing the incidence of surgical wound infections. Results: In two months, 74 surgical interventions were analysed. Analyse showed a 4.05 % incidence of surgical wound infection. In all cases it was superficial incisional surgical wound infection. Discussion: Prevention of surgical wound infections is becoming an important part of the national health strategies in many developed countries. Expert knowledge teaches us, that a significant part of healthcare-related infections can be prevented, often by following simple rules. With the project of prospective monitoring of surgical wound infection, we first of all want to define the incidence of surgical wound infection after various surgical interventions in children, to recognize risk factors for the occurrence of surgical wound infection and introduce appropriate preventive measures to reduce the incidence of surgical wound infection.
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Smertina, M. A., E. A. Efremova, and V. A. Marchenko. "DISTRIBUTION OF THE MAIN STRONGYLATA INFECTIONS OF HORSES IN THE PROVINCES OF THE ALTAI REPUBLIC." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”, 2023. http://dx.doi.org/10.31016/978-5-6048555-6-0.2023.24.447-452.

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The research purpose was to study the distribution of the main Strongylata infections of horses in the provinces of the Altai Republic. Infective larvae of strongylates after their cultivation were isolated by the Berman-Orlov method and subsequently identified taking into account morphometric characteristics. The ubiquitous distribution of helminths of the suborder Strongylata with heterogeneity of infection in ungulates was detected in the context of administrative districts and provinces. In the provinces as a whole and in administrative districts, species of the family Trichonematidae predominate, and their infection rate in horses significantly exceeds the infection with other strongylates (IP, 64–99%). The infection rate of nematodes of the family Strongylidae, including Strongylus, Alfortia and Delafondia is 2–4 times smaller and is 31.9, 20.4 and 10.6%, respectively. On the farms of the Southeastern Altai (Kosh-Agachsky District), the invasion of ungulates with strongylates in general including Trichonema, Alfortia and Delafondia is 2-10 times lower than in other districts of the Republic and amounts to 59.6, 51.6, 4.8 and 3.2%, respectively. The sharp difference in the infection of animals in this region in our opinion is mainly associated with the topographic and landscape features of the area and is due to the low heat supply and aridity of the climate in most of the territory.
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Thomas, Swapna, Maria K. Smatti, Muna A. Al Maslamani, and Hadi Mohamad Yassine. "Influenza Prevalence and Vaccine Efficacy in Diabetic Patients in Qatar." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0112.

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Introduction: Diabetes (DM) is often recognized as ‎an independent risk factor for developing severe respiratory tract infections. Influenza infections are associated with higher hospitalization, morbidity and mortality in DM patients. Vaccination against Influenza virus would reduce the burden of flu infection in DM patients. Aim: To assess the prevalence and burden of influenza infection in DM patients in Qatar and to evaluate the efficacy of influenza vaccination in DM patients Methods: The study included 26,989 patients between 2016- 2018. Virology test results (20 pathogens) as well as the levels of HbA1c were collected for all participant. Data was filtered and analysed to explore the influenza prevalence and vaccine efficiacy among diabetis patients in comparision to non-diabetic. Findings: This study shows that DM patients are at higher-risk for influenza infection. In general, Influenza infections covers around 50 % of total respiratory infections in patients with flu like symptoms in Qatar. However, in vaccinated DM patients, influenza test positivity was low. This study reports the efficacy of routine flu vaccination to reduce the burden of influenza infection in DM patients.
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Mallia, Patrick, Joseph Footitt, Maria-Belen Trujillo-Torralbo, Gregory Oleszkiewicz, Abbie Omolu, Marco Contoli, Simon Message, Alberto Papi, Sebastian L. Johnston, and Onn Min Kon. "Bacterial Infections Following Experimental Rhinovirus Infection In COPD." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3728.

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Reports on the topic "Infection"

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Loynichan, A. T., and D. L. Hank Harris. Infectious Dose Determination of Acute Salmonella Infection in Swine. Ames (Iowa): Iowa State University, January 2005. http://dx.doi.org/10.31274/ans_air-180814-1098.

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Jones, Katherine, Patrick Finley, Thomas Moore, Linda Nozick, Nathaniel Martin, Alisa Bandlow, Richard Detry, Leland Evans, and Taylor Berger. Varicella infection modeling. Office of Scientific and Technical Information (OSTI), September 2013. http://dx.doi.org/10.2172/1096254.

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Becker, William K., William G. Cioffi, McManus Jr, Kim Albert T., McManus Seung H., and William F. Fungal Burn Wound Infection. Fort Belvoir, VA: Defense Technical Information Center, January 1991. http://dx.doi.org/10.21236/ada245443.

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Jenkins, J. Lee, Edbert B. Hsu, Anna Russell, Allen Zhang, Lisa M. Wilson, and Eric B. Bass. Infection Prevention and Control for the Emergency Medical Services and 911 Workforce. Agency for Healthcare Research and Quality (AHRQ), November 2022. http://dx.doi.org/10.23970/ahrqepctb42.

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Objectives. To summarize current evidence on exposures to infectious pathogens in the emergency medical services (EMS) and 911 workforce, and on practices for preventing, recognizing, and controlling occupationally acquired infectious diseases and related exposures in that workforce. Review methods. We obtained advice on how to answer four Guiding Questions by recruiting a panel of external experts on EMS clinicians, State-level EMS leadership, and programs relevant to EMS personnel, and by engaging representatives of professional societies in infectious diseases and emergency medicine. We searched PubMed®, Embase®, CINAHL®, and SCOPUS from January 2006 to March 2022 for relevant studies. We also searched for reports from State and Federal Government agencies or nongovernmental organizations interested in infection prevention and control in the EMS and 911 workforce. Results. Twenty-five observational studies reported on the epidemiology of infections in the EMS and 911 workforce. They did not report demographic differences except for a higher risk of hepatitis C in older workers and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in minorities. EMS clinicians certified/licensed in Advanced Life Support have a high risk for blood and fluid exposure, and EMS clinicians had a higher risk of hospitalization or death from SARS-CoV-2 than firefighters whose roles were not primarily related to medical care. Eleven observational studies reported on infection prevention and control practices (IPC), providing some evidence that hand hygiene, standard precautions, mandatory vaccine policies, and on-site vaccine clinics are effective. Research on IPC in EMS and 911 workers has increased significantly since the SARS-CoV-2 pandemic. Conclusions. Moderate evidence exists on the epidemiology of infections and effectiveness of IPC practices in EMS and 911 workers, including hand hygiene, standard precautions, mandatory vaccine policies, and vaccine clinics. Most evidence is observational, with widely varying methods, outcomes, and reporting. More research is needed on personal protective equipment effectiveness and vaccine acceptance, and better guidance is needed for research methods in the EMS and 911 worker setting.
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Chejanovsky, Nor, Diana Cox-Foster, Victoria Soroker, and Ron Ophir. Honeybee modulation of infection with the Israeli acute paralysis virus, in asymptomatic, acutely infected and CCD colonies. United States Department of Agriculture, December 2013. http://dx.doi.org/10.32747/2013.7594392.bard.

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Honey bee (Apis mellifera) colony losses pose a severe risk to the food chain. The IAPV (Israeli acute paralysis virus) was correlated with CCD, a particular case of colony collapse. Honey bees severely infected with IAPV show shivering wings that progress to paralysis and subsequent death. Bee viruses, including IAPV, are widely present in honey bee colonies but often there are no pathological symptoms. Infestation of the beehive with Varroa mites or exposure to stress factors leads to significant increase in viral titers and fatal infections. We hypothesized that the honey bee is regulating/controlling IAPV and viral infections in asymptomatic infections and this control is broken through "stress" leading to acute infections and/or CCD. Our aims were: 1. To discover genetic changes in IAPV that may affect tissue tropism in the host, and/or virus infectivity and pathogenicity. 2. To elucidate mechanisms used by the host to regulate/ manage the IAPV-infection in vivo and in vitro. To achieve the above objectives we first studied stress-induced virus activation. Our data indicated that some pesticides, including myclobutanil, chlorothalonil and fluvalinate, result in amplified viral titers when bees are exposed at sub lethal levels by a single feeding. Analysis of the level of immune-related bee genes indicated that CCD-colonies exhibit altered and weaker immune responses than healthy colonies. Given the important role of viral RNA interference (RNAi) in combating viral infections we investigated if CCD-colonies were able to elicit this particular antiviral response. Deep-sequencing analysis of samples from CCD-colonies from US and Israel revealed high frequency of small interfering RNAs (siRNA) perfectly matching IAPV, Kashmir bee virus and Deformed wing virus genomes. Israeli colonies showed high titers of IAPV and a conserved RNAi pattern of targeting the viral genome .Our findings were further supported by analysis of samples from colonies experimentally infected with IAPV. Following for the first time the dynamics of IAPV infection in a group of CCD colonies that we rescued from collapse, we found that IAPV conserves its potential to act as one lethal, infectious factor and that its continuous replication in CCD colonies deeply affects their health and survival. Ours is the first report on the dominant role of IAPV in CCD-colonies outside from the US under natural conditions. We concluded that CCD-colonies do exhibit a regular siRNA response that is specific against predominant viruses associated with colony losses and other immune pathways may account for their weak immune response towards virus infection. Our findings: 1. Reveal that preventive measures should be taken by the beekeepers to avoid insecticide-based stress induction of viral infections as well as to manage CCD colonies as a source of highly infectious viruses such as IAPV. 2. Contribute to identify honey bee mechanisms involved in managing viral infections.
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Bailey, C. R., B. Greatorex, Y. Hyde, R. Koerner, N. McGuire, T. Meek, and S. Radhakrishna. Infection prevention and control 2020. The Association of Anaesthetists, January 2020. http://dx.doi.org/10.21466/g.ipac2.2020.

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Rupprecht, Ruth M. Immunotherapy of Congenital SIV Infection. Fort Belvoir, VA: Defense Technical Information Center, October 1998. http://dx.doi.org/10.21236/ada358457.

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Nayar, Gayathri, and Susan Kim Jacobson. Prophylaxis, infection prevention and control. BJUI Knowledge, November 2019. http://dx.doi.org/10.18591/bjuik.0733.

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Yang, Ming, Youwei Wu, Tao Wang, and Wentao Wang. Iron overload, Infectious Complications and Survival In Liver Transplant Recipients: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0022.

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Review question / Objective: Iron overload conditions is a well-established risk factor for infection of pathogens. The possible association of iron overload with infectious complications and prognosis of patients receiving transplants are not well understood. Condition being studied: Liver transplantation often represents a life-saving treatment for an increasing number of patients with end-stage liver disease. With the improvements in surgical techniques, immunosuppression strategies, and post-LT management of complications, the recipient mortality has steadily declined after LT. The survival rates were 83% at 1 year, 71% at 5 years in western countries. However, the use of immunosuppressants increased risk of infections as an adverse effect resulting in severe morbidity. Globally, infection caused by including bacteria, fungus, viruses remain one of the leading causes of morbidity and mortality among transplant recipients. Knowledge of modifiable risk factors and potentially reversible causes is essential to develop targeted preventive strategies.
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Black, Robert E., Myron M. Levine, Mary L. Clements, Timothy P. Hughes, and Martin J. Blaser. Experimental Campylobacter Jejuni Infection in Humans. Fort Belvoir, VA: Defense Technical Information Center, March 1988. http://dx.doi.org/10.21236/ada265410.

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