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1

Jafarian, Saleh, Masoud Amiri, and Mahmoud Mobasheri. "The Effect of Twin Birth on Neonatal and Infant Mortality Rates: A Systematic Review." International Journal of Epidemiologic Research 5, no. 3 (September 18, 2018): 113–18. http://dx.doi.org/10.15171/ijer.2018.24.

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Background and aims: Twin birth may account for higher mortality rates in infants and neonates. To investigate the potential relationship between twin birth and infant and neonatal mortality rates (NMRs), a systematic review was conducted. Methods: To gather the evidence for the relationship between twin birth and its potential effect on mortality during infancy and neonatal periods, a systematic review was conducted. The most important used databases were PubMed, Google Scholar, Web of Science, Scopus, ProQuest, Cochrane and Springer. Then, the databases were searched by appropriate keywords. After reviewing and evaluating the collected studies, trends in the different countries were compared. Results: A total of 13 790 related studies were found, of which 128 studies were selected in the first step. The studies which were not related to the subject, in addition to repetitive studies, were excluded from the search in the second step based on inclusion and exclusion criteria by reviewing the abstract and, in some cases, the full article. Finally, 7 studies entered the last step. Conclusion: This study showed that the mortality could be higher among twins than among non-twins, especially among boys.
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Verstraeten, Barbara S. E., Jane Mijovic-Kondejewski, Jun Takeda, Satomi Tanaka, and David M. Olson. "Canada’s pregnancy-related mortality rates: doing well but room for improvement." Clinical & Investigative Medicine 38, no. 1 (February 6, 2015): 15. http://dx.doi.org/10.25011/cim.v38i1.22410.

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Purpose: Canada’s perinatal, infant and maternal mortality rates were examined and compared with other Organization for Economic Cooperation and Development (OECD) countries. The type and the quality of the available data and best practices in several OECD countries were evaluated. Source: A literature search was performed in PubMed and the Cochrane Library. Vital statistics data were obtained from the OECD Health Database and Statistics Canada and subjected to secondary analysis. Principal findings: Overall, Canadian pregnancy mortality rates have fallen dramatically since the early 1960’s. Perinatal and infant mortality rates remain low and stable, but the maternal mortality rate has increased slightly and both mortality rates have declined in their relative OECD rankings over the last 20 years. Data quality and coverage across Canada and internationally, especially for Indigenous peoples, is inconsistent and registration practices differ greatly, making comparisons difficult. Available data do show that Indigenous people’s perinatal and infant mortality rates are nearly twice those of the general population. Best practices in other OECD countries include Australia’s National Maternity Services plan to improve Aboriginal perinatal health, the Netherlands’ midwifery services and National Perinatal Registry and Japan’s national pregnancy registration and Maternal Handbook. Conclusion: To diminish Canadian disparities in perinatal health rates and improve health outcomes we recommend a) uniform registration practices across Canada, b) better data quality and coverage especially among Indigenous communities, c) adoption of a national pregnancy registration and a maternal handbook along with d) improved midwifery and primary practice services to rural and remote communities. At a time when Canada is focusing upon improving pregnancy health in developing nations, it also needs to address its own challenges in improving pregnancy outcomes.
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Paes, Bosco, Ian Mitchell, Abby Li, Tetsuhiro Harimoto, and Krista L. Lanctôt. "Respiratory-Related Hospitalizations following Prophylaxis in the Canadian Registry for Palivizumab (2005–2012) Compared to Other International Registries." Clinical and Developmental Immunology 2013 (2013): 1–15. http://dx.doi.org/10.1155/2013/917068.

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Respiratory syncytial virus (RSV) infection occurs commonly in infants aged ≤2 years, and severe infection results in hospitalization with accompanying morbidity and mortality. Palivizumab has been available for prophylaxis for the past 15 years. Prospective data on patients who received palivizumab from 2005 to 2012 has been assembled in the Canadian registry (CARESS) to document utilization, compliance, and health outcomes in both hospital and community settings. Long-term data is necessary to evaluate the impact of palivizumab on the incidence of RSV infections, minimize healthcare resources, and identify which infant subpopulations are receiving prophylaxis. A database search was also conducted for similar information from published registries, and hospitalization rates were compared to results from randomized clinical trials (RCTs).Overall hospitalization rates (percent; range) for respiratory-related illnesses and RSV-specific infection in infants who meet standard indications for prophylaxis were 6.6 (3.3–7.7) and 1.55 (0.3–2.06), respectively, in CARESS, which closely aligns with registry data from 4 other countries, despite the former comprising the largest cohort of complex patients internationally. Overall RSV-related hospitalization rates were lower across registries compared to equivalent patients in RCTs. Registry data provides valuable information regarding real-world experience with palivizumab, while facilitating the genesis of new research themes.
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Rudge, Marilza Vieira Cunha, Silvana Andrea Molina Lima, Regina Paolucci El Dib, Gabriela Marini, Claudia Magalhaes, and Iracema de Mattos Paranhos Calderon. "Effect of ambulatory versus hospital treatment for gestational diabetes or hyperglycemia on infant mortality rates: a systematic review." Sao Paulo Medical Journal 131, no. 5 (2013): 331–37. http://dx.doi.org/10.1590/1516-3180.2013.1315560.

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CONTEXT AND OBJECTIVE: Pregnancies complicated by diabetes are associated with increased neonatal and maternal complications. The most serious maternal complication is the risk of developing type 2 diabetes, 10-12 years after the delivery. For rigorous control over blood glucose, pregnant women are treated through ambulatory management or hospitalization. The aim of this study was to evaluate the effectiveness of ambulatory management versus hospitalization in pregnancies complicated by diabetes or hyperglycemia. DESIGN AND SETTING: Systematic review conducted in a public university hospital. METHODS: A systematic review of the literature was performed and the main electronic databases were searched. The date of the most recent search was September 4, 2011. Two authors independently selected relevant clinical trials, assessed their methodological quality and extracted data. RESULTS: Only three studies were selected, with small sample sizes. There was no statistically significance different between ambulatory management and hospitalization, regarding mortality in any of the subcategories analyzed: perinatal and neonatal deaths (relative risk [RR] 0.65; 95% confidential interval [CI]: 0.11 to 3.84; P = 0.63); neonatal deaths (RR 0.29; 95% CI: 0.01 to 6.07; P = 0.43); and infant deaths (RR 0.29; 95% CI: 0.01 to 6.07; P = 0.43). CONCLUSIONS: This review, based on studies with high or moderate risk of bias, showed that there was no statistically significant difference between ambulatory management and hospital care, regarding reduction of mortality rates in pregnancies complicated by diabetes or hyperglycemia. It also suggested that there is a need for further randomized controlled trials on this issue.
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Hut, Janneke. "In Search of Affirmed Aboriginality as Christian: “If you do not walk on the tracks of your grandparents, you will get lost . . .”." Exchange 41, no. 1 (2012): 19–43. http://dx.doi.org/10.1163/157254312x618771.

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Abstract The marginalized position in which the Indigenous peoples of Australia find themselves today is undeniable. Within the tragedy of low life-expectancy, high rates of substance abuse, malnutrition, poor housing, high infant mortality, deaths in custody etc. lies a spiritual crisis. This crisis is aggravated by the circumstance that the loss of the land to the European invaders has caused a loss of Aboriginal identity. In their attempt to recover from this colonial legacy the Aborigines try to re-find their (religious) self-identity and to unite through Aboriginality. In this search for Aboriginal identity through spirituality and faith some Christian theologians explore the possibilities of an Aboriginal contextual theology as a response to this crisis.
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Ivanov, Dmitry O., and Kseniia G. Shevtsova. "Analysis of selected statistical indicators of the North-Western Federal district in aspect of infant mortality and stillbirths." Pediatrician (St. Petersburg) 9, no. 2 (May 15, 2018): 5–15. http://dx.doi.org/10.17816/ped925-15.

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The paper presents results of some analyzed statistical indicators of infant mortality and stillbirth in the North-Western Federal District of Russia. The following indicators are considered: availability of medical personnel and inpatient beds, morbidity of pregnant women, the number of abortions, as well as some socio-economic indicators. The negative correlation between infant mortality rate in the region and availability of obstetricians-gynecologists, pediatricians, neonatologists was revealed. Stillbirth rates in the region were found to be related to the provision of pregnant pathology beds, to the proportion of these beds in the total number of obstetric beds, to provision of the population with obstetricians and gynecologists. In addition, both factors are equally dependent on such index of work of women's family planning counseling services as the number of abortions per 100 live and stillbirths. A comparative analysis of the pregnant women morbidity, together with the investigated medical care provision in the region, emphasized the effective organization of the child protection and child delivery service activity in the North-Western Federal District, on the one hand. On the other hand, it determined that, in the search for a reserve of reducing fetal and infantile losses in North-Western Federal District, the priority area is a differentiated study of the pregnant women morbidity aimed at developing an appropriate comprehensive prevention program to reduce of the pregnant women morbidity.
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Goley, Stephanie Michele, Sidonie Sakula-Barry, Nana Adofo-Ansong, Laurence Isaaya Ntawunga, Maame Tekyiwa Botchway, Ann Horton Kelly, and Naomi Wright. "Investigating the use of ultrasonography for the antenatal diagnosis of structural congenital anomalies in low-income and middle-income countries: a systematic review." BMJ Paediatrics Open 4, no. 1 (August 2020): e000684. http://dx.doi.org/10.1136/bmjpo-2020-000684.

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BackgroundCongenital anomalies are the fifth leading cause of under-5 mortality globally. The greatest burden is faced by those in low/middle-income countries (LMICs), where over 95% of deaths occur. Many of these deaths may be preventable through antenatal diagnosis and early intervention. This systematic literature review investigates the use of antenatal ultrasound to diagnose congenital anomalies and improve the health outcomes of infants in LMICs.MethodsA systematic literature review was conducted using three search strings: (1) structural congenital anomalies; (2) LMICs; and (3) antenatal diagnosis. The search was conducted on the following databases: Medline, Embase, PubMed and the Cochrane Library. Title, abstract and full-text screening was undertaken in duplicate by two reviewers independently. Consensus among the wider authorship was sought for discrepancies. The primary analysis focused on the availability and effectiveness of antenatal ultrasound for diagnosing structural congenital anomalies. Secondary outcomes included neonatal morbidity and mortality, termination rates, referral rates for further antenatal care and training level of the ultrasonographer. Relevant policy data were sought.ResultsThe search produced 4062 articles; 97 were included in the review. The median percentage of women receiving an antenatal ultrasound examination was 50.0% in African studies and 90.7% in Asian studies (range 6.8%–98.8%). Median detection rates were: 16.7% Africa, 34.3% South America, 34.7% Asia and 47.3% Europe (range 0%–100%). The training level of the ultrasound provider may affect detection rates. Four articles compared morbidity and mortality outcomes, with inconclusive results. Significant variations in termination rates were found (0%–98.3%). No articles addressed referral rates.ConclusionAntenatal detection of congenital anomalies remains highly variable across LMICs and is particularly low in sub-Saharan Africa. Further research is required to investigate the role of antenatal diagnosis for improving survival from congenital anomalies in LMICs.PROSPERO registration numberCRD42019105620.
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Angia Sari, Intan Dewi, Muhammad Ilham Aldika Akbar, and Atika Atika. "Neonatal Death in Women with Severe Preeclampsia Receiving Conservative Management: Literature Review." KESANS : International Journal of Health and Science 1, no. 10 (July 20, 2022): 876–82. http://dx.doi.org/10.54543/kesans.v1i10.93.

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Introduction: In developing countries that still have places with inadequate supporting facilities, equipment and limited trained personnel, infants less than 37 weeks may still be at high risk for severe complications and even death if active management or termination is carried out, so conservative care is recommended. Object: The aim of this study was to analyze the perinatal outcome of neonatal mortality in women with severe preeclampsia who received conservative management. Method: This study uses a literature review method which includes searching for articles in electroncic research journal databases. Search articles using Scopus and Google Scholar with no year limit. The keywords used in the search were Preeclampsia, Conservative Management, Expectative Management, and Perinatal Outcomes. A total of 637 articles were obtained, and six articles were analyzed based on the research setting, design study, samples characteristics, and research results for each article. Results and Discussion: of this study are conservative management of women with severe preeclampsia can reduce neonatal mortality rates in care in developed countries, but still shows high rates of care in developing countries. Conclusion: of the results, this study indicate that conservative management can improve maternal outcomes in the form of neonatal mortality in developed countries
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Ichihara, Maria Yury, Andrêa J. F. Ferreira, Camila S. S. Teixeira, Flávia Jôse O. Alves, Aline Santos Rocha, Victor Hugo Dias Diógenes, Dandara Oliveira Ramos, et al. "Mortality inequalities measured by socioeconomic indicators in Brazil: a scoping review." Revista de Saúde Pública 56 (October 10, 2022): 85. http://dx.doi.org/10.11606/s1518-8787.2022056004178.

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OBJECTIVE Summarize the literature on the relationship between composite socioeconomic indicators and mortality in different geographical areas of Brazil. METHODS This scoping review included articles published between January 1, 2000, and August 31, 2020, retrieved by means of a bibliographic search carried out in the Medline, Scopus, Web of Science, and Lilacs databases. Studies reporting on the association between composite socioeconomic indicators and all-cause, or specific cause of death in any age group in different geographical areas were selected. The review summarized the measures constructed, their associations with the outcomes, and potential study limitations. RESULTS Of the 77 full texts that met the inclusion criteria, the study reviewed 24. The area level of composite socioeconomic indicators analyzed comprised municipalities (n = 6), districts (n = 5), census tracts (n = 4), state (n = 2), country (n = 2), and other areas (n = 5). Six studies used composite socioeconomic indicators such as the Human Development Index, Gross Domestic Product, and the Gini Index; the remaining 18 papers created their own socioeconomic measures based on sociodemographic and health indicators. Socioeconomic status was inversely associated with higher rates of all-cause mortality, external cause mortality, suicide, homicide, fetal and infant mortality, respiratory and circulatory diseases, stroke, infectious and parasitic diseases, malnutrition, gastroenteritis, and oropharyngeal cancer. Higher mortality rates due to colorectal cancer, leukemia, a general group of neoplasms, traffic accident, and suicide, in turn, were observed in less deprived areas and/or those with more significant socioeconomic development. Underreporting of death and differences in mortality coverage in Brazilian areas were cited as the main limitation. CONCLUSIONS Studies analyzed mortality inequalities in different geographical areas by means of composite socioeconomic indicators, showing that the association directions vary according to the mortality outcome. But studies on all-cause mortality and at the census tract level remain scarce. The results may guide the development of new composite socioeconomic indicators for use in mortality inequality analysis.
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Wirayuda, Anak Agung Bagus, and Moon Fai Chan. "A Systematic Review of Sociodemographic, Macroeconomic, and Health Resources Factors on Life Expectancy." Asia Pacific Journal of Public Health 33, no. 4 (January 7, 2021): 335–56. http://dx.doi.org/10.1177/1010539520983671.

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This review was aimed at systematically synthesizing and appraising the existing literature of sociodemographic, macroeconomic, and health resources factors on life expectancy. A systematic literature search of English databases, that is, PubMed/MEDLINE were scrutinized for exploring sociodemographic, macroeconomic, and health resources factors on life expectancy. The literature search was conducted in January 2020, covering a total of 46 articles from 2004 to 2019 met the review criteria, which were fully discussed subsequently. Among sociodemographic factors, infant mortality rate, literacy rate, education level, socioeconomic status, population growth, and gender inequality have a significant impact on life expectancy. Gross domestic product, Gini, income level, unemployment rate, and inflation rate are the main macroeconomic factors that significantly correlated with life expectancy. Among various health care resources, health care facilities, the number of the health care profession, public health expenditure, death rates, smoking rate, pollution, and vaccinations had a significant correlation with life expectancy. The systematic review showed general conformity of different studies, with a significant association between life expectancy and factors comprising several sociodemographic, macroeconomic, and various health care variables. This review found that only one study examined factors affecting life expectancy in Arabic countries. More studies on this region to fill this research gap were highly recommended.
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Walther, Felix, Denise Bianca Küster, Anja Bieber, Mario Rüdiger, Jürgen Malzahn, Jochen Schmitt, and Stefanie Deckert. "Impact of regionalisation and case-volume on neonatal and perinatal mortality: an umbrella review." BMJ Open 10, no. 9 (September 2020): e037135. http://dx.doi.org/10.1136/bmjopen-2020-037135.

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ObjectiveThis umbrella review summarises and critically appraises the evidence on the effects of regulated or high-volume perinatal care on outcome among very low birth weight/very preterm infants born in countries with neonatal mortality <5/1000 births.Intervention/expositionPerinatal regionalisation, centralisation, case-volume.Primary outcomesDeath.Secondary outcomesDisability, discomfort, disease, dissatisfaction.MethodsOn 29 November 2019 a systematic search in MEDLINE and Embase was performed and supplemented by hand search. Relevant systematic reviews (SRs) were critically appraised with A MeaSurement Tool to Assess systematic Reviews 2.ResultsThe literature search revealed 508 hits and three SRs were included. Effects of perinatal regionalisation were assessed in three (34 studies) and case-volume in one SR (6 studies). Centralisation has not been evaluated. The included SRs reported effects on ‘death’ (eg, neonatal), ‘disability’ (eg, mental status), ‘discomfort’ (eg, maternal sensitivity) and ‘disease’ (eg, intraventricular haemorrhages). ‘Dissatisfactions’ were not reported. The critical appraisal showed a heterogeneous quality ranging from moderate to critically low. A pooled effect estimate was reported once and showed a significant favour of perinatal regionalisation in terms of neonatal mortality (OR 1.60, 95% CI 1.33–1.92). The qualitative evidence synthesis of the two SRs without pooled estimate suggests superiority of perinatal regionalisation in terms of different mortality and non-mortality outcomes. In one SR, contradictory results of lower neonatal mortality rates were reported in hospitals with higher birth volumes.ConclusionsRegionalised perinatal care seems to be a crucial care strategy to improve the survival of very low birth weight and preterm births. To overcome the low and critically low methodological quality and to consider additional clinical and patient-reported results that were not addressed by the SRs included, we recommend an updated SR. In the long term, an international, uniformly conceived and defined perinatal database could help to provide evidence-based recommendations on optimal strategies to regionalise perinatal care.PROSPERO registration numberCRD42018094835.
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Khullar, Dhruv, Ahmed M. I. Andeejani, and Ketan R. Bulsara. "Evolution of treatment options for vein of Galen malformations." Journal of Neurosurgery: Pediatrics 6, no. 5 (November 2010): 444–51. http://dx.doi.org/10.3171/2010.8.peds10231.

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Object Vein of Galen aneurysmal malformations (VGAMs) continue to account for high morbidity and mortality rates in the pediatric population. Whereas in the past, mortality rates were nearly 100%, recent developments in endovascular embolization and improvements in neonatal care have improved prognoses. It is now possible that some patients can achieve normal neurological development following embolization of the VGAM. Access to the lesion can be gained via transarterial or transvenous routes. In this paper the authors review the pathophysiological characteristics of VGAM and discuss the evolution of treatment options. Methods A PubMed literature search was performed for vein of Galen malformation treatment options, beginning in the 1970s. A total of 22 papers were reviewed in full, and outcome data for 615 patients from 1983 to 2010 were compiled. Articles were reviewed if they focused primarily on the treatment of VGAM and reported outcomes for at least 5 treated patients. Results Of the 265 patient outcomes reported between 1983 and 2000, 200 received endovascular therapy. Of these patients 72% had a favorable outcome, and a 15% mortality rate was found. Microsurgery was found to have an 84.6% mortality rate. Furthermore, 76.7% of untreated patients died. More recently, endovascular embolization has become the mainstay of VGAM treatment. Of the 350 patients assessed between 2001 and 2010, 337 were treated endovascularly, mostly via the transarterial approach. Of these patients, 84.3% were found to have good or fair outcomes, and a 15.7% mortality rate was found. Neonates had the worst clinical outcomes following endovascular treatment, with a 35.6% mortality rate, whereas infants and children had significantly better outcomes, with mortality rates of 6.5% and 3.2%, respectively. Conclusions Endovascular embolization has considerably improved outcomes in patients with VGAM. In the past, the prognosis for patients with VGAM was dismal, and successful procedures were considered to be those that partially or completely obliterated the lesion, but did not necessarily improve the patient's symptoms. More recently, with the continued development and improvement of endovascular techniques, many patients are found to be neurologically normal on follow-up, and mortality rates have dropped substantially when compared with microsurgical treatment.
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El Moussawi, M. A. E., Zh V. Mironenkova, S. Z. Umarov, O. I. Knysh, and O. D. Nemyatykh. "COMPARATIVE ANALYSIS OF LEBANON DEVELOPMENT. PROSPECTS FOR COOPERATION WITH THE RUSSIAN FEDERATION." Pharmacy & Pharmacology 8, no. 3 (December 21, 2020): 205–18. http://dx.doi.org/10.19163/2307-9266-2020-8-3-205-218.

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The objective of the research was to conduct a comparative analysis of the development of Lebanon based on a number of demographic, economic and social indicators characterizing the health care of Lebanon, and to determine the prospects for the cooperation with the Russian Federation (RF) in the pharmacy field.Materials and methods. The studies were conducted from 2009 to 2016. The objects were the statistical data accumulated on the basis of the data from national institutions and international organizations. These data were published annually in the reports of the Department of Economic and Social Affairs, the United Nations Population Division for 11 countries in the Middle East: Bahrain, Jordan, Yemen, Kuwait, Lebanon, United Arab Emirates, Oman, Saudi Arabia (Asian countries); Egypt, Sudan, Tunisia (North African countries). The research methods were: a comparative analysis, analytical grouping of data, ranking.Results. A comparative analysis of demographic, economic and social indicators revealed that low mortality rates and high life expectancy in Lebanon were achieved both due to a satisfactory level of health care financing (Rank 5) and due to the adoption of adequate decisions in organizing and managing the Lebanese health care system. The positive trends that were inherent in the Lebanese health care system in previous decades continued to operate within the framework of earlier inertia, while migration flows intensified. However, there has been a slowdown in the decline in infant mortality in the dynamics of growth rates, which is a signal of the emergence of negative processes in the social sphere of the country.Conclusion. The current situation in the Lebanese health care system, associated with limited financial resources, poses new challenges in the search for managerial decisions in the field of organizational management. The import of drugs from the Russian Federation will provide a significant reduction in the financial costs of providing the population of Lebanon and migrants with medicines which will increase the monetary costs of providing medical care.
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Panjaitan, Arip Ambulan. "MODEL OF PREVENTION OF ADOLESCENT UNWANTED PREGNANCY IN INDONESIA: REVIEW ARTICLE." INTERNATIONAL JOURNAL OF RESEARCH IN LAW, ECONOMIC AND SOCIAL SCIENCES 1, no. 2 (December 8, 2019): 60–73. http://dx.doi.org/10.32501/injuriless.v1i2.125.

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Adolescent reproductive health problems are an international problem. Circumstances that occur in Indonesia, young women are more afraid of social risks such as virginity loss, extramarital pregnancies that will be a source of public gossip compared to sexual risk, which concerns reproductive health and sexual health. This study aims to collect and analyze articles relating to the development of reproductive health models based on needs, needs, schools, culture and family as an effort to prevent pregnancy in adolescents. The method used is literature review, articles are collected using search engines such as EBSCO, Sciencedirect, googlesholar. The criteria for the articles used are those published in 1995-2018. Based on the results that the reproductive health situation of young women is a problem behind the still high maternal and infant mortality rates. This condition is exacerbated by other factors such as early marriage, early pregnancy, STIs, HIV and AIDS and non-communicable diseases such as breast and cervical cancer, abortion, premarital sex, nutrition and others. Exposure of adolescent girls to reproductive health from the social environment about health education through adolescent approaches involving peers, BK teachers, family or parents, health workers and stakeholders. Information about reproductive health issues, besides being important to be known by health care providers, decision makers, is also important for stakeholders, so that they can help reduce reproductive health problems for young women.
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Heidary, Zohreh, Omid Kohandel, Hanieh Fathi, Majid Zaki-Dizaji, Marjan Ghaemi, and Batool Hossein Rashidi. "Maternal and Neonatal Complications, Outcomes and Possibility of Vertical Transmission in Iranian Women with COVID-19." Archives of Iranian Medicine 24, no. 9 (September 1, 2021): 713–21. http://dx.doi.org/10.34172/aim.2021.104.

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Background: The emergence and fast spread of coronavirus disease 2019 (COVID-19) threatens the world as a new public health crisis. Little is known about its effects during pregnancy. This study aimed to investigate the clinical manifestations of COVID-19 on maternal and neonatal outcomes. Methods: In this systematic review, PubMed, Scopus, Web of Science, and Google Scholar databases were searched focusing on pregnancy and perinatal outcomes of COVID-19. Results: The initial search yielded 1236 articles, from which finally 21 unique studies, involving 151 pregnant women and 17 neonates, met the criteria. Mean ± SD age of included mothers and mean ± SD gestational age at admission were 30.6 ± 6.2 years and 30.8 ± 8.9 weeks, respectively. The common symptoms were fever, cough, fatigue, dyspnea and myalgia. The mortality rates of pregnant women and neonates were 28 out of 151 (18.5%) and 4 out of 17 (23.5%), respectively. Most of the neonates were preterm at the time of delivery. Three neonates had positive RT-PCR test on the first day after birth and three others on day two. On the average, neonate’s PCR became positive on day 4 for the first time. Conclusion: Early diagnosis of COVID-19 is crucial due to the possibility of the prenatal complications. Strict prevention strategies may reduce the risk of mother to infant transmission.
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Fell, Deshayne B., Jeanene Johnson, Zohar Mor, Mark A. Katz, Becky Skidmore, Kathleen M. Neuzil, Justin R. Ortiz, and Niranjan Bhat. "Incidence of laboratory-confirmed influenza disease among infants under 6 months of age: a systematic review." BMJ Open 7, no. 9 (September 2017): e016526. http://dx.doi.org/10.1136/bmjopen-2017-016526.

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ObjectivesThe aim of this systematic review was to assess incidence rates of laboratory-confirmed influenza (LCI) outcomes among infants under 6 months of age.DesignSystematic literature search and review of indexed studies in PubMed, EMBASE, the Cochrane Library and CINAHL Plus from inception to 19 April 2017.SettingPopulation-based estimates from community or hospital settings.ParticipantsInfants under 6 months of age.Primary and secondary outcome measuresLCI illness in ambulatory care settings, LCI hospitalisation, LCI intensive care unit admission and LCI death. Only studies with population-based incidence data were included.ResultsWe identified 27 primary studies, 11 of which were from the USA, four were from other non-US high-income settings and the remaining were from lower-middle-income or upper-middle-income countries. Most studies (n=23) assessed incidence of LCI hospitalisation, but meta-analysis to pool study-specific rates was not possible due to high statistical and methodological heterogeneity. Among US studies, the reported incidence of LCI hospitalisation ranged from 9.3 to 91.2 per 10 000 infants under 6 months for seasonal influenza, while the only US-based estimate for pandemic H1N1 influenza was 20.2 per 10 000 infants. Reported rates for LCI hospitalisation for seasonal influenza from other countries ranged from 6.2 to 73.0 per 10 000 infants under 6 months, with the exception of one study with an estimated rate of 250 per 10 000 infants. No events were reported in five of the nine studies that evaluated LCI death among infants under 6 months.ConclusionOur review of published studies found limited data on LCI outcomes for infants under 6 months, particularly from non-US settings. Globally representative and reliable incidence data are necessary to fully evaluate influenza disease burden and the potential impact of maternal influenza immunisation programme on morbidity and mortality in young infants.
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Tchamo, M. E., A. Prista, and C. G. Leandro. "Low birth weight, very low birth weight and extremely low birth weight in African children aged between 0 and 5 years old: a systematic review." Journal of Developmental Origins of Health and Disease 7, no. 4 (April 13, 2016): 408–15. http://dx.doi.org/10.1017/s2040174416000131.

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Low birth weight (LBW<2500), very low birth weight (VLBW<1500), extremely low birth weight (ELBW<1500) infants are at high risk for growth failure that result in delayed development. Africa is a continent that presents high rates of children born with LBW, VLBW and ELBW particularly sub-Saharan Africa. To review the existing literature that explores the repercussions of LBW, VLBW and ELBW on growth, neurodevelopmental outcome and mortality in African children aged 0–5 years old. A systematic review of peer-reviewed articles using Academic Search Complete in the following databases: PubMed, Scopus and Scholar Google. Quantitatives studies that investigated the association between LBW, VLBW, ELBW with growth, neurodevelopmental outcome and mortality, published between 2008 and 2015 were included. African studies with humans were eligible for inclusion. From the total of 2205 articles, 12 articles were identified as relevant and were subsequently reviewed in full version. Significant associations were found between LBW, VLBW and ELBW with growth, neurodevelopmental outcome and mortality. Surviving VLBW and ELBW showed increased risk of death, growth retardation and delayed neurodevelopment. Post-neonatal interventions need to be carried out in order to minimize the short-term effects of VLBW and ELBW.
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Lemma, Dereje, Tufa Kolola Huluka, and Legese Chelkeba. "Prevalence and antimicrobial susceptibility of group B streptococci among pregnant women in Ethiopia: A systemic review and meta-analysis study." SAGE Open Medicine 10 (January 2022): 205031212210813. http://dx.doi.org/10.1177/20503121221081338.

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Objective: Maternal colonization or infection with drug-resistant Group B streptococcus is a serious disease that affects mother, fetus, and infant. The knowledge of maternal colonization and antimicrobial susceptibility test is substantially needed for a nation to formulate a policy or change the already existing one to reduce maternal, fetus, and infant mortality. As a result, the goal of this review was to determine the pooled prevalence Group B streptococcus colonization and antimicrobial susceptibility among Ethiopian pregnant women. Methods: Literature searches were carried out in the electronic biomedical databases and indexing services such as PubMed/MEDLINE, Scopus, Science Direct, Web of Science, and Google Scholar. Original records of research articles, available online from 2014 to December 2020, addressing prevalence and antimicrobial-resistance pattern of Group B streptococcus in pregnant women were identified and screened. Endnote citation manager software version X9 for windows was utilized to collect and organize search outcomes and for removal of duplicate articles. The relevant data were extracted from included studies using a format prepared in Microsoft Excel and exported to STATA 14.0 software for the outcome measures analyses and subgrouping. The I2 index was used to measure heterogeneity between studies and median, and interquartile (25%, 75%) was used to assess antimicrobial susceptibility rate. Results and conclusion: Sixteen original articles were found in both qualitative and quantitative analyses. Group B streptococcus colonization was recorded in 979 of the 5743 pregnant women, resulting in a 16% overall frequency (95% confidence interval: 13%−20%). The estimated prevalence varied significantly between studies with significant heterogeneity (χ2 = 154.31, p = 0.001, I2 = 90.28). Ampicillin (97.8%; interquartile range = 89.5%−100%), penicillin G (95.5%; interquartile range = 89.5%−100%), and vancomycin (100%; interquartile range = 89.5%−100%) susceptibility were all high in Group B streptococcus, whereas tetracycline (29%; interquartile range = 89.5%−100%) susceptibility was low. Group B streptococcus colonization rates in Ethiopian women during pregnancy were virtually similar to those in many underdeveloped countries, and Group B streptococcus isolates were highly sensitive to ampicillin, penicillin G, and vancomycin.
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Pek, Jen Heng, Ming Ying Gan, Bei Jun Yap, Shu Ting Tammie Seethor, Rachel G. Greenberg, Christoph Paul Vincent Hornik, Bobby Tan, Jan Hau Lee, and Shu-Ling Chong. "Contemporary trends in global mortality of sepsis among young infants less than 90 days old: protocol for a systematic review and meta-analysis." BMJ Open 10, no. 7 (July 2020): e038815. http://dx.doi.org/10.1136/bmjopen-2020-038815.

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IntroductionNeonatal sepsis has a high mortality rate that varies across different populations. We aim to perform a contemporary global evidence synthesis to determine the case fatality rates of neonatal sepsis, in order to better delineate this public health urgency and inform strategies to reduce fatality in this high-risk population.Methods and analysisWe will search PubMed, Cochrane Central, Embase and Web of Science for articles in English language published between January 2010 and December 2019. All clinical trials and observational studies involving infants less than 90 days old with a clinical diagnosis of sepsis and reported case fatality rate will be included. Two independent reviewers will screen the studies and extract data on study variables chosen a priori. Quality of evidence and risk of bias will be assessed using Cochrane Collaboration’s tool and ROBINS-I. Results will be synthesised qualitatively and pooled for meta-analysis.Ethics and disseminationNo formal ethical approval is required as there is no collection of primary data. This systematic review and meta-analysis will be disseminated through conference meetings and peer-reviewed publications.PROSPERO registration numberCRD42020164321.
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Thompson, Julie M., Stephanie M. Eick, Cody Dailey, Ariella P. Dale, Mansi Mehta, Anjali Nair, José F. Cordero, and Michael Welton. "Relationship Between Pregnancy-Associated Malaria and Adverse Pregnancy Outcomes: a Systematic Review and Meta-Analysis." Journal of Tropical Pediatrics 66, no. 3 (October 10, 2019): 327–38. http://dx.doi.org/10.1093/tropej/fmz068.

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Abstract Background Pregnancy-associated malaria (PAM) has been associated with adverse pregnancy outcomes like preterm birth (PTB) and low birthweight (LBW), which are among the leading causes of infant mortality globally. Rates of PTB and LBW are high in countries with a high burden of malaria. PAM may be a contributing factor to PTB and LBW, but is not well understood. Methods We conducted a systematic review and meta-analysis of studies examining the relationship between PAM and PTB or LBW using PubMed. The title and abstract of all studies were screened by two reviewers, and the full text of selected studies was reviewed to ensure they met inclusion criteria. Information regarding study characteristics and of PTB and LBW births among women with and without PAM was abstracted for included studies. Results Our search terms yielded 2237 articles, of which 18 met our final inclusion criteria. Eight studies examined associations between PAM and PTB, and 10 examined associations between PAM and LBW (population size ranging from 35 to 9956 women). The overall risk of LBW was 63% higher among women with PAM compared with women without PAM (95% CI = 1.48–1.80) and the risk of PTB was 23% higher among women with PAM compared with women without PAM (95% CI = 1.07–1.41). Conclusions These results indicate that infection with PAM is associated with PTB and LBW. Further understanding of the pathogenesis of disease and the immunologic changes that occur during pregnancy is essential for reducing the disproportional effects this disease has on this vulnerable population.
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York, Jaclyn B., Megan Z. Cardoso, Dara S. Azuma, Kristyn S. Beam, Geoffrey G. Binney, and Saul N. Weingart. "Computerized Physician Order Entry in the Neonatal Intensive Care Unit: A Narrative Review." Applied Clinical Informatics 10, no. 03 (May 2019): 487–94. http://dx.doi.org/10.1055/s-0039-1692475.

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Background Computerized physician order entry (CPOE) has grown since the early 1990s. While many systems serve adult patients, systems for pediatric and neonatal populations have lagged. Adapting adult CPOE systems for pediatric use may require significant modifications to address complexities associated with pediatric care such as daily weight changes and small medication doses. Objective This article aims to review the neonatal intensive care unit (NICU) CPOE literature to characterize trends in the introduction of this technology and to identify potential areas for further research. Methods Articles pertaining to NICU CPOE were identified in MEDLINE using MeSH terms “medical order entry systems,” “drug therapy,” “intensive care unit, neonatal,” “infant, newborn,” etc. Two physician reviewers evaluated each article for inclusion and exclusion criteria. Consensus judgments were used to classify the articles into five categories: medication safety, usability/alerts, clinical practice, clinical decision Support (CDS), and implementation. Articles addressing pediatric (nonneonatal) CPOE were included if they were applicable to the NICU setting. Results Sixty-nine articles were identified using MeSH search criteria. Twenty-two additional articles were identified by hand-searching bibliographies and 6 articles were added after the review process. Fifty-five articles met exclusion criteria, for a final set of 42 articles. Medication safety was the focus of 22 articles, followed by clinical practice (10), CDS (10), implementation (11), and usability/alerts (4). Several addressed more than one category. No study showed a decrease in medication safety post-CPOE implementation. Within clinical practice articles, CPOE implementation showed no effect on blood glucose levels or time to antibiotic administration but showed conflicting results on mortality rates. Implementation studies were largely descriptive of single-hospital experiences. Conclusion CPOE implementation within the NICU has demonstrated improvement in medication safety, with the most consistent benefit involving a reduction in medication errors and wrong-time administration errors. Additional research is needed to understand the potential limitations of CPOE systems in neonatal intensive care and how CPOE affects mortality.
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Joseph, K. "Infant Mortality Rates." ACOG Clinical Review 2, no. 2 (March 4, 1997): 3. http://dx.doi.org/10.1016/s1085-6862(97)80992-2.

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Goley, Stephanie Michele, Sidonie Sakula-Barry, Ann Kelly, and Naomi Wright. "Investigating the use of ultrasonography for the antenatal diagnosis of structural congenital anomalies in low-income and middle-income countries: systematic review protocol." BMJ Paediatrics Open 3, no. 1 (September 2019): e000538. http://dx.doi.org/10.1136/bmjpo-2019-000538.

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IntroductionCongenital anomalies are the fifth leading cause of mortality in children under 5 years globally. The greatest burden is faced by those in developing countries, where over 95% of deaths occur. Many of these deaths may have been preventable through antenatal diagnosis and early intervention. This study aims to conduct a systematic review that investigates the use of antenatal ultrasound to diagnose congenital anomalies and improve the health outcomes of infants in low-income and middle-income countries (LMICs).Methods and analysisA systematic literature review will be conducted using three search strings: (1) structural congenital anomalies, (2) LMICs and (3) antenatal diagnosis. Four electronic databases will be searched: MEDLINE, Embase, PubMed and the Cochrane Library. Title, abstract and full-text screening will be undertaken in duplicate by two reviewers independently using Covidence. Consensus will be sought from the wider authorship for discrepancies. Data extraction will be undertaken by the principal investigator. The primary analysis will focus on the availability and effectiveness of antenatal ultrasound for structural congenital anomalies. Secondary outcomes will include neonatal morbidity and mortality, termination rates and referral rates for further antenatal care. Descriptive statistics and a narrative synthesis will be included in the final report. The methodological quality of the included studies will be evaluated using the Cochrane-approved Risk of Bias for Non-Randomised Studies of Intervention and Risk of Bias in Randomised Trials V.2.0 tools.Ethics and disseminationEthical approval is not required for conducting the systematic review as there will be no direct collection of data from individuals. The results will be submitted for publication in a scientific journal and presented internationally.ConclusionThis is the first study, to our knowledge, to systematically review current literature on the use of antenatal ultrasound for the detection of congenital anomalies in LMICs. This is vital to define current practice, highlight global disparities and evaluate effects on health outcomes for infants in low-resource settings.PROSPERO registration numberCRD42019105620.
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Yordanov, Y. "Probiotic Use in Preterm Neonates: A Review and Bibliometric Analysis." Acta Medica Bulgarica 49, no. 3 (October 1, 2022): 58–67. http://dx.doi.org/10.2478/amb-2022-0032.

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Abstract Background: Necrotizing enterocolitis (NEC) is a major health burden in peterm neonates with mortality rates between 21% and 50%. Prophylaxis is of primary importance as early diagnosis is hindered by the lack of specific signs and laboratory markers. Although probiotics have been routinely used for NEC prophylaxis in neonatal intensive care units around the world, clinical trials provide contradictory data, which fuels an ongoing debate about their efficacy and safety. Aims: To perform a review and bibliometric analysis on available clinical trials and case reports data on the safety and efficacy of probiotics in preterm neonates and identify relevant publication trends and patterns. Methods: A bibliometric search for publications on the topic was performed in the Web of Science Core Collection database and the resulting records analyzed in bibliometrix package in R. Results: Trends in publication activity, historical direct citation network relationships and keyword co-ocurrences were discussed in the context of the most recent therapeutic recommendations. Conclusion: We took a round view of the potential drawbacks to probiotic use in preterm infants and their possible solutions.
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Kruse, Clemens, Jose Betancourt, Stephanie Ortiz, Susana Melissa Valdes Luna, Inderdeep Kaur Bamrah, and Narce Segovia. "Barriers to the Use of Mobile Health in Improving Health Outcomes in Developing Countries: Systematic Review." Journal of Medical Internet Research 21, no. 10 (October 9, 2019): e13263. http://dx.doi.org/10.2196/13263.

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Background The use of mobile health (mHealth) technologies to improve population-level health outcomes around the world has surged in the last decade. Research supports the use of mHealth apps to improve health outcomes such as maternal and infant mortality, treatment adherence, immunization rates, and prevention of communicable diseases. However, developing countries face significant barriers to successfully implement, sustain, and expand mHealth initiatives to improve the health of vulnerable populations. Objective We aimed to identify and synthesize barriers to the use of mHealth technologies such as text messaging (short message service [SMS]), calls, and apps to change and, where possible, improve the health behaviors and health outcomes of populations in developing countries. Methods We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. Deriving search criteria from the review’s primary objective, we searched PubMed and CINAHL using an exhaustive terms search (eg, mHealth, text messaging, and developing countries, with their respective Medical Subject Headings) limited by publication date, English language, and full text. At least two authors thoroughly reviewed each article’s abstract to verify the articles were germane to our objective. We then applied filters and conducted consensus meetings to confirm that the articles met the study criteria. Results Review of 2224 studies resulted in a final group of 30 articles for analysis. mHealth initiatives were used extensively worldwide for applications such as maternal health, prenatal care, infant care, HIV/AIDS prevention, treatment adherence, cardiovascular disease, diabetes, and health education. Studies were conducted in several developing countries in Africa, Asia, and Latin America. From each article, we recorded the specific health outcome that was improved, mHealth technology used, and barriers to the successful implementation of the intervention in a developing country. The most prominent health outcomes improved with mHealth were infectious diseases and maternal health, accounting for a combined 20/30 (67%) of the total studies in the analysis. The most frequent mHealth technology used was SMS, accounting for 18/30 (60%) of the studies. We identified 73 individual barriers and grouped them into 14 main categories. The top 3 barrier categories were infrastructure, lack of equipment, and technology gap, which together accounted for 28 individual barriers. Conclusions This systematic review shed light on the most prominent health outcomes that can be improved using mHealth technology interventions in developing countries. The barriers identified will provide leaders of future intervention projects a solid foundation for their design, thus increasing the chances for long-term success. We suggest that, to overcome the top three barriers, project leaders who wish to implement mHealth interventions must establish partnerships with local governments and nongovernmental organizations to secure funding, leadership, and the required infrastructure.
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Qashqari, Fadi S. I. "Human Mastadenovirus Infections in Children: A Review of the Current Status in the Arab World in the Middle East and North Africa." Children 9, no. 9 (September 6, 2022): 1356. http://dx.doi.org/10.3390/children9091356.

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Human mastadenovirus (HAdV) is a non-enveloped icosahedral virus with double-stranded DNA genomes. The mortality rate of HAdV infections can reach 35.5%, while gastroenteritis HAdV infections, HAdV pneumonia, and disseminated disease tend to show a worse outcome, with rates ranging from 44.2% to 50%. In addition, HAdV can cause infections at any age but most commonly in the pediatric population, especially in young children and infants. Therefore, this review aims to assess the current status of HAdV infections among children in the Arab World, particularly in the Middle East and North Africa. Web of Science, Scopus, PubMed, EMBASE, and Google Scholar databases for publications in English were searched up to July 2022 for relevant articles. The literature search yielded a total of 21 studies, which were included in this review. Studies reporting HAdV infections in children were conducted in 17 out of the 22 countries. The average prevalence rate of HAdV infections in children was 12.7%, with average prevalence rates of 12.82% and 12.58% in the Middle East and North African countries, respectively. The highest prevalence rate (28.3%) was reported in Egypt, whereas the lowest prevalence (1.5%) was reported in Sudan. The included studies presented children with signs and symptoms of gastroenteritis, acute respiratory infection, acute diarrhea, and acute hemorrhagic conjunctivitis. In conclusion, the average prevalence rate of HAdV infections in children was 12.7%, with average prevalence rates of 12.82% and 12.58% in the Middle East and North African countries, respectively. Finding the precise prevalence rate of this virus is crucial because it will guide future planning for effective disease control and the selection of particular treatment options during epidemics and special seasons.
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Berezin, Eitan N., and Fortino Solórzano. "Gram-negative infections in pediatric and neonatal intensive care units of Latin America." Journal of Infection in Developing Countries 8, no. 08 (August 13, 2014): 942–53. http://dx.doi.org/10.3855/jidc.4590.

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In order to review the epidemiology of Gram-negative infections in the pediatric and neonatal intensive care units (PICUs and NICUs) of Latin America a systematic search of PubMed and targeted search of SciELO was performed to identify relevant articles published since 2005. Independent cohort data indicated that overall infection rates were higher in Latin American PICUs and NICUs versus developed countries (range, 5%–37% vs 6%–15%, respectively). Approximately one third of Latin American patients with an acquired PICU or NICU infection died, and crude mortality was higher among extremely low-birth-weight infants and those with an infection caused by Gram-negative bacteria. In studies reporting > 100 isolates, the frequency of Gram-negative pathogens varied from 31% (Colombia) to 63% (Mexico), with Klebsiella pneumoniae, Pseudomonas aeruginosa, and Escherichia coli the predominant pathogens in almost all countries, and Acinetobacter spp. and Serratia spp. isolated sporadically. The activity of quinolones and third-generation cephalosporins against P. aeruginosa, Acinetobacter spp., and Enterobacteria was seriously compromised, coincident with a high prevalence of circulating extended-spectrum β-lactamases. Furthermore, we identified two observational studies conducted in Chile and Brazil reporting infections by P. aeruginosa and Acinetobacter baumannii in PICUs, demonstrating resistance to carbapenems, and two outbreaks of carbapenem-resistant K. pneumoniae in Colombia and Brazil. The endemicity of multidrug-resistant Gram-negative infections in Latin American PICUs and NICUs is punctuated by intermittent clonal outbreaks. The problem may be alleviated by ensuring ICUs are less crowded, increasing staffing levels of better-trained health care personnel, and implementing antimicrobial stewardship and surveillance programs.
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Cobo, Angeles, and Eulalia Isabel Analuisa Jiménez. "PARTO HUMANIZADO Y LA FUNCIÓN DE ENFERMERÍA EN LOS ESTABLECIMIENTOS DE SALUD PÚBLICA." Enfermería Investiga 7, no. 1 (January 3, 2022): 73. http://dx.doi.org/10.31243/ei.uta.v7i1.994.2022.

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Introducción: la humanización del parto asegura el respeto de los derechos fundamentales, reproductivos y sexuales de la gestante y la familia, reduciendo complicaciones perinatales y morbi-mortalidad materno-infantil. Objetivo: Caracterizar el parto humanizado y las funciones de enfermería en los establecimientos de salud pública. Métodos: diseño documental con revisión bibliográfica sobre humanización del parto para lo cual se realizó una búsqueda en bases de datos como: PubMed, Taylor y Francis, LILACS, MEDLINE, BVS, SCIELO, LATINDEX, GOOGLE ACADÉMICO, en idioma español e inglés. Resultados: En base a revisión y análisis de 40 artículos se pudo conocer que el parto humanizado es reconocido mundialmente como una estrategia eficiente para reducir complicaciones perinatales y lograr una maternidad satisfactoria y que a nivel latinoamericano; Brasil, Perú, Argentina, Ecuador, Venezuela y México ya cuentan con iniciativas del sector público, privado y de organizaciones civiles para promocionar parto humanizado, y con ello reducir las tasas de cesáreas, parto instrumentado, morbi-mortalidad materno infantil y lograr una maternidad satisfactoria, segura basada en prácticas no invasivas ni farmacológicas para el alivio del dolor, educación y autorización sobre procedimientos, autonomía, buen trato y respeto por sentimientos y creencias. Conclusiones: En el pato humanizado, el rol de enfermería es esencial sobre todo en los establecimientos públicos en donde se asume maltrato, negligencia o falta de respeto por el parto, por lo que la enfermera está llamada a educar a la parturienta sobre el trabajo de parto y parto. Palabras clave: parto humanizado, atención perinatal, enfermería, recién nacido. ABSTRACT Introduction: the humanization of childbirth ensures respect for the fundamental, reproductive and sexual rights of the pregnant woman and the family, reducing perinatal complications and maternal and infant morbidity and mortality. Objective: To characterize humanized delivery and nursing functions in public health establishments. Methods: documentary design with bibliographic review on the humanization of childbirth for which a search was carried out in databases such as: PubMed, Taylor and Francis, LILACS, MEDLINE, BVS, SCIELO, LATINDEX, GOOGLE ACADEMICO, in Spanish and English. Results: Based on a review and analysis of 40 articles, it was possible to know that humanized delivery is recognized worldwide as an efficient strategy to reduce perinatal complications and achieve a satisfactory maternity and that at the Latin American level; Brazil, Peru, Argentina, Ecuador, Venezuela and Mexico already have initiatives from the public and private sectors and civil organizations to promote humanized delivery, and thereby reduce the rates of cesarean sections, instrumented delivery, maternal and infant morbidity and mortality and achieve motherhood, satisfactory, safe based on non-invasive or pharmacological practices for pain relief, education and authorization on procedures, autonomy, good treatment and respect for feelings and beliefs. Conclusions: In the humanized duck, the role of nursing is essential especially in public establishments where abuse, neglect or lack of respect for childbirth is assumed, so the nurse is called to educate the woman in labor about the labor of labor and delivery. Keywords: humanized delivery, perinatal care, nursing, newborn
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Hammerman, Cathy, and Pnina Zadka. "Asphyxia-Related Infant Mortality Rates." American Journal of Perinatology 11, no. 04 (July 1994): 290–94. http://dx.doi.org/10.1055/s-2007-994595.

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BABSON, S. GORHAM. "Mortality Rates." Pediatrics 84, no. 2 (August 1, 1989): 402–3. http://dx.doi.org/10.1542/peds.84.2.402a.

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We are fortunate to receive Myron Wegman's annual summary of vital statistics in the December issue of Pediatrics. This valuable information is not readily available to the pediatrician. I am somewhat discomforted by the emphasis continually made by health authorities and lay press on the United States' unfavorable international position in its infant mortality rate of 10.4 per 1000 live-born infants—now 19th in relation to other advanced countries for 1986. However, eight of these countries have less than 100 000 births each year, and most of them have relative ethnic homogeneity.
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Hubacher, David, Patricia Bailey, Barbara Janowitz, Fidel Barahona, and Marco Pinel. "Estimating infant mortality rates prospectively in Honduras." Journal of Biosocial Science 24, no. 4 (October 1992): 433–45. http://dx.doi.org/10.1017/s0021932000020009.

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SummaryIn order to determine the validity of infant mortality estimates based on retrospective reporting, the Honduran Ministry of Health carried out a follow-up survey of women interviewed in a 1987 national survey. Women were interviewed approximately 14 months after the baseline survey and were asked about the outcomes of their pregnancies and the survival status of their young children. The overall infant mortality rate calculated from the follow-up survey was lower than that obtained from the baseline survey, due to the particularly low rate among the group of women who were pregnant at the time of the baseline survey. Possible explanations for this low rate are discussed.
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Bongaarts, John. "Does Family Planning Reduce Infant Mortality Rates?" Population and Development Review 13, no. 2 (June 1987): 323. http://dx.doi.org/10.2307/1973197.

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Lester, David. "Infant Mortality among American Indians." Psychological Reports 81, no. 1 (August 1997): 146. http://dx.doi.org/10.2466/pr0.1997.81.1.146.

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Bird, Sheryl Thorburn, and Karl E. Bauman. "State-Level Infant, Neonatal, and Postneonatal Mortality: The Contribution of Selected Structural Socioeconomic Variables." International Journal of Health Services 28, no. 1 (January 1998): 13–27. http://dx.doi.org/10.2190/7ufv-cb1w-m5kd-qd9p.

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Reducing infant mortality in the United States is a national priority. States' infant mortality rates vary substantially. Public health researchers, practitioners, and leaders have long argued that social and other structural factors must be addressed if health outcomes are to be improved. A knowledge of which structural variables are most strongly related to state-level infant mortality is needed to guide the development of policies and programs to reduce this mortality. The authors examine the importance of several structural (social, economic, and political) variables for state-level infant, neonatal, and postneonatal mortality. With the state as the unit of analysis, data for all 50 states were analyzed using multiple regression. Together, the structural variables accounted for two-thirds of the variance in infant and neonatal mortality rates and over half of the variance in postneonatal mortality rates. States with proportionately larger black populations had higher infant, neonatal, and postneonatal mortality rates. States with greater percentages of high school graduates had lower neonatal mortality rates but higher postneonatal mortality rates. The findings suggest that a better understanding of the relationship between states' social structure and infant health outcomes is needed if state-level infant mortality is to be reduced.
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Lazuwardi, Burhanuddin. "LOGISTICS REGRESSION MODELING ON INFANT MORTALITY RATES IN EAST JAVA PROVINCE." Indonesian Journal of Public Health 15, no. 2 (August 4, 2020): 146. http://dx.doi.org/10.20473/ijph.v15i2.2020.146-152.

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Infant Mortality Rate was death that occurs between the time after the baby was born until the baby not exactly one year old. Broadly speaked, from the side of the caused of infant mortality there are two kinds of endogenous infant death and exogenous infant mortality. Estimated about 8.8 million children whose age less than 5 years passed away. Based on previous data IDHs indicated that infant mortality has fallen by half, from 68 deaths per 1,000 live births for the 1987-1991 period to 32 deaths per 1,000 births for the 2008-2012 period. The purposed of this researched was to examine which factor most dominant influenced on infant mortality in East Java Province.This research used secondary data with a large sample of total population that consists of parents whose children (infants) died at the age <12 months. Variables in this study was infant mortality (IMR), Occupation, Education, Parity, Age of the mother during pregnancy. Access to antenatal care, Birth delivery helpers, and LBW. Inter-variables in this study tested its effect using logistic regression test. The conclusion of this study was infant mortality rated in East Java there 34 infant mortality per 1000 live birth. Factors affecting infant mortality rates was education and parity. Factors were not influenced in infant mortality such as Antenatal Care, Relief, LBW and Employment.Keywords: Baby Birth Mortality and Logistic Regression
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MacDorman, Marian F., and T. J. Mathews. "The Challenge of Infant Mortality: Have We Reached a Plateau?" Public Health Reports 124, no. 5 (September 2009): 670–81. http://dx.doi.org/10.1177/003335490912400509.

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Objectives. Infant mortality is a major indicator of the health of a nation. We analyzed recent patterns and trends in U.S. infant mortality, with an emphasis on two of the greatest challenges: ( 1) persistent racial and ethnic disparities and ( 2) the impact of preterm and low birthweight delivery. Methods. Data from the national linked birth/infant death datasets were used to compute infant mortality rates per 100,000 live births by cause of death (COD), and per 1,000 live births for all other variables. Infant mortality rates and other measures of infant health were analyzed and compared. Leading and preterm-related CODs, and international comparisons of infant mortality rates were also examined. Results. Despite the rapid decline in infant mortality during the 20th century, the U.S. infant mortality rate did not decline from 2000 to 2005, and declined only marginally in 2006. Racial and ethnic disparities in infant mortality have persisted and increased, as have the percentages of preterm and low birthweight deliveries. After decades of improvement, the infant mortality rate for very low birthweight infants remained unchanged from 2000 to 2005. Infant mortality rates from congenital malformations and sudden infant death syndrome declined; however, rates for preterm-related CODs increased. The U.S. international ranking in infant mortality fell from 12th place in 1960 to 30th place in 2005. Conclusions. Infant mortality is a complex and multifactorial problem that has proved resistant to intervention efforts. Continued increases in preterm and low birthweight delivery present major challenges to further improvement in the infant mortality rate.
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Grosu-Creangă, Ionela-Alina, Antigona Carmen Trofor, Radu Adrian Crișan-Dabija, Daniela Robu-Popa, Cristina Mihaela Ghiciuc, and Elena Cătălina Lupușoru. "Adverse effects induced by second-line antituberculosis drugs: an update based on last WHO treatment recommendations for drug-resistant tuberculosis." Pneumologia 70, no. 3 (October 1, 2022): 117–26. http://dx.doi.org/10.2478/pneum-2022-0029.

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Abstract Introduction: Tuberculosis (TB), a common condition worldwide, is still among the main infectious diseases with high mortality rates, both in adults and infants. Drug-resistant tuberculosis (DR-TB) drugs, revised by the World Health Organization (WHO) in 2018, are a prolonged and complex therapy associated with many adverse drug effects (ADEs). Aim: To systematically review the ADEs of second-line anti-TB drugs reported in multicentric studies published after the latest WHO guidelines, compared with those from clinical trials published before 2018. Material and methods: A PubMed search, using keywords (TB OR DR-TB) AND (adverse effects) AND “second-line anti-TB drugs”, resulted in 56 studies. Only two studies, published after the last update of WHO guidelines in 2018, reported ADEs. Results: A total of 223 participants were included in the two selected studies. The use of multidrug regimens has been associated with an increased incidence of ADEs: 42 ADEs were recorded in 30 patients (26.3%) in the first study, while all patients had at least one ADE that occurred or worsened during treatment; and 19 (17%) had severe ADEs in the second study. However, both studies had a good favourable outcome rate (90% and 79.8%, respectively). Gastrointestinal disturbances, hepatotoxicity, headache and dizziness are the most common ADEs induced by a majority of second-line DR-TB treatments. A special attention should be given in the case of association of drugs determining QT interval (QT) prolongation on electrocardiogram, or psychiatric disorders. Conclusions: Proper strategies about ADE management have to be planned for timely detection of the possible ADEs that can be induced by second-line anti-TB therapy.
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Paul, David A., Amy Mackley, Robert G. Locke, John L. Stefano, and Charlan Kroelinger. "State Infant Mortality: An Ecologic Study to Determine Modifiable Risks and Adjusted Infant Mortality Rates." Maternal and Child Health Journal 13, no. 3 (May 13, 2008): 343–48. http://dx.doi.org/10.1007/s10995-008-0358-9.

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Yuswatiningsih, Endang. "Aplikasi Korelasi Kanonikal Pada Faktor – Faktor Yang Mempengaruhi Angka Kematian Ibu Dan Bayi Di Provinsi Jawa Timur." Jurnal Ilmu Kesehatan 4, no. 1 (June 14, 2017): 5. http://dx.doi.org/10.32831/jik.v4i1.68.

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The purpose of this study was to analyze the relationship between maternal and infant mortality by influenced factors and the factors most closely associated with maternal and infant mortality rates in the province of East Java in 2012. This research uses canonical correlation method that aims to determine the relationship between two variables and identify the dimensions between two groups of variables. The results showed that the variable factors that affect maternal mortality and infant mortality has a strong positive correlation to variable maternal mortality and infant mortality rate. Highest impact of the independent variables for maternal mortality is pregnancy, postpartum maternal, neonatal visits, visiting the baby and toddler care was the infant mortality rate is the delivery by the shaman, neonatal visits and infant visits.;Keywords : canonical correlation, maternal mortality rates, infant mortality rates.
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40

Swenson, Ingrid E., Nguyen Minh Thang, Pham Bich San, Vu Qui Nham, and Vu Duy Man. "Factors influencing infant mortality in Vietnam." Journal of Biosocial Science 25, no. 3 (July 1993): 285–302. http://dx.doi.org/10.1017/s0021932000020630.

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SummarySelected determinants of overall infant mortality in Vietnam were examined using data from the 1988 Vietnam Demographic and Health Survey, and factors underlying neonatal and post-neonatal mortality were also compared. Effects of community development characteristics, including health care, were studied by logistic regression analysis in a subsample of rural children from the 1990 Vietnam Accessibility of Contraceptives Survey.Infant neonatal and post-neonatal mortality rates showed comparable distributions by birth order, maternal age, pregnancy intervals, mother's education and urban–rural residence. Rates were highest among first order births, births after an interval of less than 12 months, births to illiterate mothers and to those aged under 21 or over 35 years of age. Logistic regression analysis showed that the most significant predictor of infant mortality was residence in a province where overall infant mortality was over 40 per 1000 live births. In the rural subsample, availability of public transport was the most persistent community development predictor of infant mortality. Reasons for the low infant mortality rates in Vietnam compared to countries with similar levels of economic development are discussed.
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41

Howell, E. M., and B. Blondel. "International infant mortality rates: bias from reporting differences." American Journal of Public Health 84, no. 5 (May 1994): 850–52. http://dx.doi.org/10.2105/ajph.84.5.850.

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42

Cage, R. A. "INFANT MORTALITY RATES AND HOUSING: TWENTIETH CENTURY GLASGOW." Scottish Economic & Social History 14, no. 1 (May 1994): 77–92. http://dx.doi.org/10.3366/sesh.1994.14.14.77.

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43

BATES, BETSY. "Infant Mortality Rates From Accidental Suffocation Up Sharply." Family Practice News 38, no. 13 (July 2008): 5. http://dx.doi.org/10.1016/s0300-7073(08)70797-7.

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44

Kabir, M., M. Mohiuddin Ahamed, and M. Moslehuddin. "Differential Infant and Child Mortality Rates in Bangladesh." Food and Nutrition Bulletin 8, no. 3 (September 1986): 1–6. http://dx.doi.org/10.1177/156482658600800301.

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45

Caporale, Guglielmo Maria, and Luis A. Gil-Alana. "Infant mortality rates: time trends and fractional integration." Journal of Applied Statistics 42, no. 3 (November 17, 2014): 589–602. http://dx.doi.org/10.1080/02664763.2014.980785.

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46

BARELL, VITA, YOCHANAN WAX, and AVIMA RUDER. "ANALYSIS OF GEOGRAPHIC DIFFERENTIALS IN INFANT MORTALITY RATES." American Journal of Epidemiology 128, no. 1 (July 1988): 218–30. http://dx.doi.org/10.1093/oxfordjournals.aje.a114944.

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47

Condran, Gretchen A., and Jennifer Murphy. "Defining and Managing Infant Mortality." Social Science History 32, no. 4 (2008): 473–513. http://dx.doi.org/10.1017/s0145553200010804.

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Historically, public health workers, physicians, and reformers have used the infant mortality rate as an indicator of the goodness of a society—its general welfare, the justness of its political system, the efficacy of its public works, the benevolence of its powerful; a high rate of death among the very young was an index of a community's shame. These views of the infant mortality rate as reflecting general characteristics of a society were widely displayed in the second half of the nineteenth century even as most disease entities were becoming more narrowly defined and ordinarily linked not to the nature of society or individual predisposition but to specific pathological organisms. Using Philadelphia as a case study, we examine the history of the infant mortality rate from 1870 through 1920, both the technical aspects of its calculation and its use as an indicator of broad societal problems and a catalyst for policy. Our emphasis is not on explaining the trends in the death rates of the very young but on the uses and meanings given to the infant mortality rate during the second half of the nineteenth century and the first decades of the twentieth century specifically as they related to three efforts to lower infant death rates—removing infants from the city, improving the supply of milk, and establishing child hygiene programs.
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48

Jason, Janine M. "Infectious Disease-Related Deaths of Low Birth Weight Infants, United States, 1968 to 1982." Pediatrics 84, no. 2 (August 1, 1989): 296–303. http://dx.doi.org/10.1542/peds.84.2.296.

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Infant mortality rates in the United States are higher than in any other developed country. Low birth weight (LBW) is the primary determinant of infant mortality. Despite city, state, and federal programs to prevent LBW, decreases in infant mortality in the 1980s appear to be largely secondary to improved survival of LBW infants rather than to a decline in the rate of LBW births. Because prevention of mortality due to infectious disease is feasible, it was of interest to examine the role of infectious diseases in LBW infant mortality. US vital statistics mortality data for 1968 through 1982 were analyzed in terms of LBW infant mortality associated with infectious and noninfectious diseases. These analyses indicated that the rates of infectious disease-associated early neonatal and postneonatal LBW mortality increased during this time; late neonatal rates did not decline appreciably. Infectious diseases were associated with 4% of all LBW infant deaths in 1968; this had increased to 10% by 1982. Although LBW infant mortality rates associated with noninfectious diseases did not differ for white and black populations, infectious disease-associated mortality rates were consistently higher for blacks than whites in both metropolitan and nonmetropolitan areas. Chorioamnionitis was involved in 28% of infectious disease-associated early neonatal LBW deaths. Sepsis was an increasingly listed cause of death in all infant age periods, whereas respiratory tract infections were decreasingly listed. Necrotizing enterocolitis increased as a cause of late neonatal mortality. These data suggest that infectious diseases are an increasing cause of LBW infant mortality and these deaths occur more frequently in the black population targeted by prevention programs. More research concerning specific causes and prevention of infections in the LBW infant may help reduce US infant mortality.
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Shawky, S. "Infant mortality in Arab countries: sociodemographic, perinatal and economic factors." Eastern Mediterranean Health Journal 7, no. 06 (December 15, 2001): 956–65. http://dx.doi.org/10.26719/2001.7.6.956.

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The infant mortality rates for 1978 and 1998 of 16 Arab countries in the Eastern Mediterranean region were studied. The data were extracted from World Health Organization and United Nations Children’s Fund sources. The impact of demographic, social, perinatal care and economic indicators on infant mortality rates in 1998 was studied using Spearman rank coefficient to detect significant correlations. All countries, except Iraq, showed a sharp decline in rates from 1978 to 1998. Infant mortality rates were directly related to population size, annual total births, low birth weight and maternal mortality ratios. Also, infant mortality rates were inversely related to literacy status of both sexes, annual gross national product per capita and access to safe drinking-water and adequate sanitation facilities.
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50

Lester, David. "Regional Suicide Rates in Scotland." Psychological Reports 106, no. 1 (February 2010): 134. http://dx.doi.org/10.2466/pr0.106.1.134.

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