Academic literature on the topic 'In-vivo Skin analysis'

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Journal articles on the topic "In-vivo Skin analysis"

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Cal, Krzysztof, Daniel Zakowiecki, and Justyna Stefanowska. "Advanced tools for in vivo skin analysis." International Journal of Dermatology 49, no. 5 (April 26, 2010): 492–99. http://dx.doi.org/10.1111/j.1365-4632.2010.04355.x.

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Ishikawa, Tomohisa. "In vivo analysis of skin microcirculation in rats and mice." Folia Pharmacologica Japonica 132, no. 2 (2008): 79–82. http://dx.doi.org/10.1254/fpj.132.79.

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Jachowicz, J., R. McMullen, and D. Prettypaul. "Indentometric analysis of in vivo skin and comparison with artificial skin models." Skin Research and Technology 13, no. 3 (August 2007): 299–309. http://dx.doi.org/10.1111/j.1600-0846.2007.00229.x.

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Flores, Ignacio, Gerard Evan, and María A. Blasco. "Genetic Analysis of Myc and Telomerase Interactions In Vivo." Molecular and Cellular Biology 26, no. 16 (August 15, 2006): 6130–38. http://dx.doi.org/10.1128/mcb.00543-06.

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ABSTRACT Myc is a transcription factor with pleiotropic effects on tumorigenesis which are likely to be mediated by its target genes. A known Myc transcriptional target is the catalytic subunit of telomerase, Tert. However, the contribution of Tert activation to Myc-induced tumorigenesis in vivo remains unknown. In this study, we addressed the role of telomerase in Myc-induced skin papillomatosis by using compound mice with a switchable Myc gene, Inv-MycERTAM mice, in combination with either telomerase deficiency (Terc−/−) or telomerase overexpression (K5-mTert) in the skin. We first demonstrated that Myc activates telomerase in the skin. With Inv-MycERTAM × Terc−/− mice, we further showed that this telomerase activation is partially required to elicit a full hyperplastic Myc-induced response. The presence of critically short telomeres in late-generation Inv-MycERTAM × Terc−/− mice further reduced the skin lesion induced by Myc. On the other hand, telomerase overexpression in the skin of K5-mTert mice augments Myc-induced hyperplasia in the absence of changes in telomere length, suggesting a direct role of telomerase in the Myc protumorigenic response. Taken together, these results highlight telomerase as a mediator of Myc-induced papillomatosis and suggest telomerase as a putative therapeutic target for Myc-dependent lesions.
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Knyazkova, A. I., A. A. Samarinova, V. V. Nikolaev, Y. V. Kistenev, and A. V. Borisov. "Features two-photon microscopy for analysis fluorescent properties of elastin fibers rats in vivo." Izvestiya vysshikh uchebnykh zavedenii. Fizika, no. 11 (2021): 128–33. http://dx.doi.org/10.17223/00213411/64/11/128.

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This paper presents the results of in vivo visualization of elastin fibers of the papillary layer of rat skin obtained using two-photon microscopy. It is shown that, when approximating the fluorescence decay curve by a two-exponential model, the obtained parameters for rat dermis elastin and human elastin fibers have similar distributions.
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Preiss, Ivor L., and William Washington. "Skin Thickness Effects on In Vivo LXRF." Advances in X-ray Analysis 38 (1994): 607–13. http://dx.doi.org/10.1154/s0376030800018309.

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Abstract The analysis of lead concentration in bone utilizing LXRF can be adversely effected by overlymg tissue. A quantitative measure of the attenuation of the 10.5 keV Pb L a x-ray signal by skin and skin equivalent plastic has been conducted. Concentration ranges in plaster of Paris and doped goat bone from 7 to 90 ppm with attenuators of Lucite® and pig skin were examined. It is concluded that no quantitative or semi quantitative analysis can be achieved if overlying tissue thickness exceeds 3 mm for Pb concentrations of less than 30 ppm Pb in bone.
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Elsayad, Khaled, Christos Moustakis, Manuela Simonsen, Dagmar Bäcker, Uwe Haverkamp, and Hans Theodor Eich. "In-vivo dosimetric analysis in total skin electron beam therapy." Physics and Imaging in Radiation Oncology 6 (April 2018): 61–65. http://dx.doi.org/10.1016/j.phro.2018.05.002.

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Lim, Grace J., Yozo Ishiuji, Aerlyn G. Dawn, Benjamin Harrison, Do Won Kim, Anthony Atala, and Gil Yosipovitch. "In vitro and In vivo Characterization of a Novel Liposomal Butorphanol Formulation for Treatment of Pruritus." Acta Dermato-Venereologica 88, no. 4 (May 9, 2008): 327–30. http://dx.doi.org/10.2340/00015555-0480.

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As yet no transdermal topical formulations have been developed for the treatment of chronic itch. We developed a formulation containing 2 mg butorphanol tartrate in 100 microl purified water encapsulated into multilamellar phospholipid vesicles. Drug permeation experiments were studied with Franz diffusion chambers using human skin in vitro and on rat skin in vivo. Histological analysis of rat skins was performed to evaluate skin irritation of the formulation in vivo. Physical properties showed stable formulation with desirable viscosity. In vitro dermal penetration rate data suggest that there was significant permeation at time-points 2 h and 4 h, and a steady state was achieved afterwards to 24 h. Maximal plasma butorphanol concentration was noted at 2 h and steady state was achieved at 8 h. Visual skin assessment as well as histological analysis of excised rat skin did not demonstrate any evidence of inflammation and irritation. In vitro and in vivo analysis demonstrated release of a consistent amount of butorphanol in a sustained manner for 24 h. This liposomal transdermal delivery formulation could serve as a method to deliver butorphanol for patients with chronic pruritus.
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Koivuranta-Vaara, Päivi. "Neutrophil migration in vivo: Analysis of a skin window technique." Journal of Immunological Methods 79, no. 1 (May 1985): 71–78. http://dx.doi.org/10.1016/0022-1759(85)90393-x.

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Donadio, Vincenzo, Zerui Wang, Alex Incensi, Giovanni Rizzo, Enrico Fileccia, Veria Vacchiano, Sabina Capellari, et al. "In Vivo Diagnosis of Synucleinopathies." Neurology 96, no. 20 (April 9, 2021): e2513-e2524. http://dx.doi.org/10.1212/wnl.0000000000011935.

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ObjectiveTo determine whether (1) immunofluorescence is a reproducible technique in detecting misfolded α-synuclein in skin nerves and subsequently whether (2) immunofluorescence and real-time quaking-induced conversion (RT-QuIC) (both in skin and CSF) show a comparable in vivo diagnostic accuracy in distinguishing synucleinopathies from non-synucleinopathies in a large cohort of patients.MethodsWe prospectively recruited 90 patients fulfilling clinical and instrumental diagnostic criteria for all synucleinopathies variants and non-synucleinopathies (mainly including Alzheimer disease, tauopathies, and vascular parkinsonism or dementia). Twenty-four patients with mainly peripheral neuropathies were used as controls. Patients underwent skin biopsy for immunofluorescence and RT-QuIC; CSF was examined in patients who underwent lumbar puncture for diagnostic purposes. Immunofluorescence and RT-QuIC analysis were made blinded to the clinical diagnosis.ResultsImmunofluorescence showed reproducible results between 2 pairs of neighboring skin samples. Both immunofluorescence and RT-QuIC showed high sensitivity and specificity in discriminating synucleinopathies from non-synucleinopathies and controls but immunofluorescence presented higher diagnostic accuracy. Immunofluorescence presented a good level of agreement with RT-QuIC in both skin and CSF in synucleinopathies.ConclusionsBoth immunofluorescence and RT-QuIC showed high diagnostic accuracy, although immunofluorescence displayed the better value as well as optimal reproducibility; they presented a good level of agreement in synucleinopathies, supporting the use of less invasive tests such as skin immunofluorescence or RT-QuIC instead of CSF RT-QuIC as a diagnostic tool for synucleinopathies.Classification of EvidenceThis study provides Class III evidence that immunofluorescence or RT-QuIC accurately distinguish synucleinopathies from non-synucleinopathies.
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Dissertations / Theses on the topic "In-vivo Skin analysis"

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Mahmud, Jamaluddin. "Development of a novel technique in measuring human skin deformation in vivo to determine its mechanical properties." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/54890/.

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Gevaux, Lou. "3D-hyperspectral imaging and optical analysis of skin for the human face." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSES035.

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L’imagerie hyperspectrale (HSI), une méthode non invasive permettant de mesurer in vivo la réflectance spectrale, a démontré son fort potentiel pour l’analyse des propriétés optiques de la peau pour des zones planes et de petite taille : l’association d’un modèle optique de peau, d’une modélisation de ses interactions avec la lumière et d’une méthode d’optimisation permet d’analyser l’image hyperspectrale en chaque pixel et d’estimer des cartographies de concentrations en chromophores, comme la mélanine et le sang. Le but de ce travail est l’extension de la méthode pour la mesure et l’analyse de surfaces larges et non planes, et en particulier du visage humain. Les mesures d’objets complexes comme le visage sont affectées par des variations spatiales d’éclairement, que l’on appelle dérives d’éclairement. A moins d’être prises en compte dans le modèle, celles-ci créent des erreurs dans l’analyse des images.Nous proposons en 1ère partie de ce travail une caméra HSI grand-champ (acquisition de bandes spectrales de 10 nm de largeur entre 400 et 700 nm), combinée avec un système d’acquisition de la géométrie 3D par projection de franges. Une acquisition courte étant cruciale in vivo, un compromis entre résolution et vitesse d’acquisition permet un temps d’acquisition inférieur à 5 secondes.La caméra HSI a été associée avec un scanner 3D afin de corriger les dérives d’éclairement en utilisant la géométrie 3D et des principes de radiométrie. L’éclairement reçu par le visage est calculé en chaque pixel puis utilisé pour supprimer les dérives d’éclairement dans l’image hyperspectrale, un prétraitement à appliquer avant l’analyse. Cependant, cette méthode n’est pas satisfaisante sur les zones du visage pratiquement perpendiculaires à l’axe optique de la caméra, comme les côtés du nez, et a été rejetée en faveur d’un algorithme d’optimisation robuste aux dérives d’éclairement dans la méthode d’analyse.L’analyse de la peau à partir des images hyperspectrales est basée sur l’utilisation de modèles optiques. La peau est modélisée par un matériau translucide à deux couches dont les propriétés d’absorption dépendent de sa composition en chromophores. Les interactions lumière-peau sont modélisées à l’aide d’une approche à deux flux. La résolution d’un problème inverse par optimisation permet d’estimer la composition en chromophores à partir de la réflectance spectrale mesurée. Les modèles optiques choisis sont un bon compromis entre une description fidèle de la peau et un temps de calcul acceptable, qui augmente de manière exponentielle avec le nombre de paramètres du modèle. Les cartes de chromophores estimées peuvent être affichées sous forme 3D grâce à l’information mesurée par la caméra HSI-3D.Un point faible de la méthode est le manque d’information sur les propriétés de diffusion de la peau, considérées identiques d’une personne à l’autre et d’une partie du corps à l’autre. Dans la 2nd partie de ce travail, nous utilisons le projecteur de franges initialement dédié à l’acquisition 3D, pour mesurer la fonction de transfert de modulation (FTM) de la peau, qui fournit de l’information sur l’absorption et la diffusion. La FTM est mesurée par imagerie dans le domaine fréquentiel spatial (SFDI) et analysée avec l’équation de la diffusion pour estimer le coefficient de diffusion de la peau. Sur des objets non-plats, l’extraction d’information indépendamment des dérives d’éclairement est un défi important. L’originalité de la méthode proposée repose sur l’association de la HSI et SFDI dans le but d’estimer des cartes de coefficient de diffusion sur le visage indépendamment de sa forme.Nous insistons sur l’importance d’une acquisition courte pour des mesures in vivo, cependant, l’analyse par optimisation demande plusieurs heures de calcul. L’utilisation des réseaux de neurones comme alternative à l’optimisation nous semble prometteur, des premiers résultats ayant montré une forte réduction du temps de calcul, d’environ 1 heure à 1 seconde
Hyperspectral imaging (HSI), a non-invasive, in vivo imaging method that can be applied to measure skin spectral reflectance, has shown great potential for the analysis of skin optical properties on small, flat areas: by combining a skin model, a model of light-skin interaction and an optimization algorithm, an estimation of skin chromophore concentration in each pixel of the image can be obtained, corresponding to quantities such as melanin and blood. The purpose of this work is to extend this method to large, non-flat areas, in particular the human face. The accurate measurement of complex objects such as the face must account for variances of illumination that result from the 3D geometry of an object, which we call irradiance drifts. Unless they are accounted for, irradiance drifts will lead to errors in the hyperspectral image analysis.In the first part of the work, we propose a measurement setup comprising a wide field HSI camera (with an acquisition range of 400 - 700 nm, in 10 nm width wavebands) and a 3D measurement system using fringe projection. As short acquisition time is crucial for in vivo measurement, a trade-off between resolution and speed has been made so that the acquisition time remains under 5 seconds.To account for irradiance drifts, a correction method using the surface 3D geometry and radiometry principles is proposed. The irradiance received on the face is computed for each pixel of the image, and the resulting data used to suppress the irradiance drifts in the measured hyperspectral image. This acts as a pre-processing step to be applied before image analysis. This method, however, failed to yield satisfactory results on those parts of the face almost perpendicular to the optical axis of the camera, such as the sides of the nose, and was therefore discarded in favor of using an optimization algorithm robust to irradiance drifts in the analysis method.Skin analysis from the measured hyperspectral image is performed using optical models and an optimization method. Skin is modeled as a two-layer translucent material whose absorption and scattering properties are determined by its composition in chromophores. Light-skin interactions are modeled using a two-flux method. An inverse problem is solved by optimization to retrieve information about skin composition from the measured reflectance. The chosen optical models represent a trade-off between accuracy and acceptable computation time, which increases exponentially with the number of parameters in the model. The resulting chromophore maps can be added to the 3D mesh measured using the 3D-HSI camera for display purposes.In the spectral reflectance analysis method, skin scattering properties are assumed to be the same for everyone and on every part of the body, which represents a shortcoming. In the second part of this work, the fringe projector originally intended for measuring 3D geometry is used to acquire skin modulation transfer function (MTF), a quantity that yields information about both skin absorption and scattering coefficients. The MTF is measured using spatial frequency domain imaging (SFDI) and analyzed by an optical model relying on the diffusion equation to estimate skin scattering coefficients. On non-flat objects, retrieving such information independently from irradiance drifts is a significant challenge. The novelty of the proposed method is that it combines HSI and SFDI to obtain skin scattering coefficient maps of the face independently from its shape.We emphasize throughout this dissertation the importance of short acquisition time for in vivo measurement. The HSI analysis method, however, is extremely time-consuming, preventing real time image analysis. A preliminary attempt to address this shortcoming is presented, using neural networks to replace optimization-based analysis. Initial results of the method have been promising, and could drastically reduce calculation time from around an hour to a second
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Mainreck, Nathalie. "Apport potentiel de la spectroscopie Raman dans le traitement chirurgical des carcinomes cutanés (CBC)." Thesis, Reims, 2017. http://www.theses.fr/2017REIMS028/document.

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Le carcinome basocellulaire (CBC) est un cancer cutané très fréquent représentant un problème de santé publique majeur. Il métastase rarement mais peut devenir très invasif localement s’il n’est pas pris en charge rapidement. Actuellement, le diagnostic de certitude du CBC est obtenu par examen anatomopathologique de coupes fines ; ce qui présente pour inconvénient d’être invasif et de donner une réponse différée. De plus, la chirurgie du CBC ne bénéficie pas d’outil permettant de définir en temps réel la largeur optimale des marges de sécurité ; celles-ci devant être minimales pour éviter les séquelles esthétiques mais suffisantes pour empêcher toute récidive. L’objectif de ces travaux de thèse est d’évaluer l’apport potentiel de la spectroscopie Raman dans la prise en charge du CBC. Cette technologie applicable in vivo grâce au développement de sondes adaptées, permet une exploration tissulaire à un niveau moléculaire relativement rapide. Au total, 32 patients ont été inclus dans cette étude. A partir des spectres enregistrés in vivo, un modèle de discrimination CBC / peau saine a été développé, à partir duquel les marges d’excision latérales ont pu être évaluées. Les marges profondes ont également été étudiées après enregistrement de spectres sur les pièces fraichement excisées. Des marqueurs Raman de discrimination ont été identifiés aux différentes échelles in vivo, ex vivo et in vitro; ils constituent des bio-indicateurs potentiels pour orienter la prise de décision chirurgicale. Enfin, la contribution des fonds spectraux, habituellement écartés des analyses Raman, a été considérée et leur intérêt dans le cadre de ce projet a été discuté
Basal cell carcinoma (BCC) is the most common skin cancer and a major problem for healthcare services worldwide. BCC rarely metastasizes but can become highly damaging for surrounding tissue in case of late diagnosis. Actually, the gold standard for BCC diagnosis relies on histopathological assessment of thin sections, but it is an invasive method which provides a delayed response. Moreover, it will be helpful during surgery of BCC to assess in real-time the optimal size of the security margins, which has to be small enough to minimize aesthetic sequelae but sufficient to avoid recurrence. The aim of this work is to evaluate the potential contribution of Raman spectroscopy in the management of BCC. This technology can be applied in vivo thanks to the development of appropriate probes and allows a relatively rapid tissue exploration at a molecular level. A total of 32 patients were included in this study. From in vivo recorded spectra, a model of discrimination BCC / healthy skin was implemented, from which the width of excision margins was evaluated. Deep margins were also studied after recording spectra on freshly excised pieces. Discriminant Raman markers were identified at different levels in vivo, ex vivo and in vitro; they are potential bio-indicators to help the surgeon to define ideal excision margins. In addition, the contribution of spectral backgrounds, usually removed from Raman analysis, was considered and their interest in this project was discussed
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LETO, BARONE Maria Stefania. "Analysis of a database to predict the result of allergy testing in vivo in patients with chronic nasal symptoms and the development of the software ARSTAT." Doctoral thesis, Università degli Studi di Palermo, 2014. http://hdl.handle.net/10447/91193.

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Background. This thesis consist of parts(i)Introduction in wich we present the clinical problem of rhinitis;(ii)the methods to evaluate the diagnostic choises;(iii)the rational errors in Allergy,(iv)the experimental part of thesis with wich we developed the software ARTSTAT,wich is the application of the analysis reported.Objective: We studied the ability of the logistic regression model obtained by the evaluaqtion of a database, to detect patients with positive allergy skin prick test(SPT)and patients with negative SPT. The model developed was valitated using the data set obtained from another medical institution. Methods: The analysis was carried out using a database obtained from a questionnaire administered to the patients with nasal symptoms containing personal data, clinical data result of allergy testing (SPT). All variables found to be significantly different between patients with positive and negative SPT(P<0.05),were selected for the logistic regression models and were analyzed with bacward stepwise logistic regression. A second set of patients from another Institution was used to prove the model. Results: e accuracyof the model identifying, over the second set, both patients whose SPT will bepositive and negative was high. The model detect 96 percent of patients with nasal symptoms and positive SPT, and classified 94 percent of those with negative SPT. Conclusion:The data of the thesis have been preliminary to the creation of a softwarewich cuold help the primary care doctors in diagnostic decision making process ( need of allergy testing), in patients complaining of chronic nasal symptoms.
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Lackermeier, A. H. "A novel multi-channel impedance analyser for the in vivo investigation of the electrical properties of human skin during transdermal drug delivery." Thesis, University of Ulster, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342315.

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Lin, Kuan-Hung, and 林冠宏. "Comparative analysis of intrinsic skin aging between Caucasian and Asian subjects by in vivo harmonic generation microscopy." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/txh6us.

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碩士
國立臺灣大學
生醫電子與資訊學研究所
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Intrinsic skin aging is defined as an inalterable process that is associated with the cellular and sub-cellular structural change of epidermis and dermis. Phenotypical and functional differences in the intrinsic skin aging process of individuals between Caucasians and Asians have generated considerable interest in dermatology and cosmetic industry. Some recent works describing racial differences in structural skin aging properties have been reported. However, most of these studies have been focused on stratum corneum and in some other studies interindividual differences in skin quality overwhelm the racial difference. Therefore, there has been a demand for more detailed studies to address various cellular and sub-cellular epidermal/dermal parameters together with age differences among different racial groups. This study investigates the morphological changes related to intrinsic skin aging in the viable epidermis and the dermal papilla zone (DPZ) between Caucasians and Asians. In contrast to other microscopies, harmonic generation microscopy (HGM) is an optimal tool to study skin aging because of the ability to distinguish the epidermis from dermis by different harmonic generation phenomena. A 1230 nm femtosecond chromium-forsterite laser was used for excitation to lessen skin attenuation and a sub-micron and 1-micron resolution in lateral and axial directions and a greater than 300 μm penetrability were previously achieved. In this study, we recruited 31 Caucasian subjects and obtained in vivo HGM images on the sun-protected volar forearm. In combination with our previous results on Asian skin, these studies allow us to comparatively analyze the difference of intrinsic aging between Caucasian and Asian skin. In comparative analysis between Caucasians and Asians, Caucasian subjects have on average larger scale in the viable epidermis thickness, the cellular size, nuclear size and NC ratio of granular cells, the depth of DPZ, the DP volume per unit area, the collagen volume per unit area, the DP volume ratio and the 3D interdigitation index. The cellular and nuclear sizes of basal cells in Caucasians increase with age with the same trend as in Asians, and the maximum viable epidermis thickness, the depth of DPZ and the DP volume per unit area in Caucasians decrease with age with highly significant difference respect to Asians. Our present findings suggest that the primary factor to result in different aging outlook between Caucasians and Asians is the DPZ-related parameters while the cellular, nuclear size of basal cells can serve as scoring indices for intrinsic skin aging due to their consistency between Caucasians and Asians.
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Kumbhar, Dipak Bhikaji. "Development and Applications of Portable Raman Spectroscopy Combined with Artificial Intelligence for Biomedicine." Thesis, 2022. https://etd.iisc.ac.in/handle/2005/6070.

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Currently, the global spectroscopic community is investigating the suitability of vibrational spectroscopy methods for point-of-care testing, histopathology, and rapid in-vivo biomedical diagnostics. Although Raman spectroscopy has many benefits, and portable Raman spectroscopy is being used in various fields successfully, currently, it has several difficulties, particularly when it comes to complex samples with low scattering cross-sections such as biological systems. The main aim of this thesis was to design and develop a portable device using Raman spectroscopy that can be utilized in conjunction with cutting-edge Artificial Intelligence (AI) techniques to obtain and analyse research-grade Raman spectrum from biological samples, which can then be further used for a variety of non-invasive biomedical investigations. Various collection and illumination optical geometries, as well as design issues, were investigated. We proposed a unique three-dimensional image reconstruction (3D tomography) approach for Universal multiple angle Raman spectroscopic (UMARS) data. Several AI/ML approaches and their significance for Raman spectroscopy with data augmentation and database standardization strategies utilized are addressed with the basic implementation of the deep learning models. We demonstrated a novel application of AI combined Raman spectroscopy for DNA-based sub-species-level classification of pathogens. In the second application, the classification of bio-carbon samples derived from pyrolysis was performed with various production conditions using Raman spectroscopy combined with deep learning algorithms such as LeNET, ResNet, and CAE. An in-house developed portable Raman spectroscopic instrument (“RAIDER”) was used to obtain the Raman spectra from complex samples such as microorganisms. Raman spectral database of highly similar 12 types of bacteria was created, and AI techniques were used for accurate classification. The instrument collected Raman signatures from a variety of bacteria samples with high SNR and compared them to commercially available benchtop instruments. Finally, the potential of an in-house developed portable Raman spectroscopic instrument for in-vivo human skin and blood analysis was explored. Research grade Raman spectra were obtained in-vivo from human skin and blood veins using in-house developed portable instrumentation with high SNR and significantly less exposure than the maximum permissible exposure limit (MPE). Further initial attempts were made to analyse in-vivo melanin content under human skin non-invasively. Variation of the melanin content was evident by biomarkers selected using PCA analysis.
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Books on the topic "In-vivo Skin analysis"

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Lackermeier, A. H. A novel multi-channel impedance analyser for the in vivo investigation of the electrical properties of human skin during transdermal drug delivery. [s.l: The Author], 2000.

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Book chapters on the topic "In-vivo Skin analysis"

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Preiss, Ivor L., and William Washington. "Skin Thickness Effects on in Vivo LXRF." In Advances in X-Ray Analysis, 607–13. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1797-9_72.

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Tomura, Michio, and Kenji Kabashima. "Analysis of Cell Movement Between Skin and Other Anatomical Sites In Vivo Using Photoconvertible Fluorescent Protein “Kaede”-Transgenic Mice." In Methods in Molecular Biology, 279–86. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-227-8_18.

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Fournier, Céline, S. Lori Bridal, and Pascal Laugier. "Application of Short-Time Fourier Multi-Narrowband Analysis to In Vivo Human Skin Between 12 and 25 MHz." In Acoustical Imaging, 167–73. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4419-8606-1_22.

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Lu-Nguyen, Ngoc, Alberto Malerba, and Linda Popplewell. "Use of Small Animal Models for Duchenne and Parameters to Assess Efficiency upon Antisense Treatment." In Methods in Molecular Biology, 301–13. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2010-6_20.

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AbstractDuchenne muscular dystrophy (DMD) is a rare genetic disease affecting 1 in 5000 newborn boys. It is caused by mutations in the DMD gene with a consequent lack of dystrophin protein that leads to deterioration of myofibers and their replacement with fibro-adipogenic tissue. Using antisense oligonucleotides (AONs) to modify out-of-frame mutations in the DMD gene, named exon skipping, is currently considered among the most promising treatments for DMD patients. The development of this strategy is rapidly moving forward, and AONs designed to skip exons 51 and 53 have received accelerated approval in the USA. In preclinical setting, the mdx mouse model, carrying a point mutation in exon 23 of the murine Dmd gene that prevents production of dystrophin protein, has emerged as a valuable tool, and it is widely used to study in vivo therapeutic approaches for DMD. Here we describe the methodology for intravenous delivery of AONs targeting dystrophin through tail vein of mdx mice. Furthermore, the most relevant functional analyses to be performed in living mice, and the most informative histopathological and molecular assays to evaluate the effect of this treatment are detailed.
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"Analysis of adhesion contact of human skin in vivo." In Contact Angle, Wettability and Adhesion, Volume 4, 513–26. CRC Press, 2006. http://dx.doi.org/10.1201/b12166-35.

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D'Amato, Roberto, and Alessandro Ruggiero. "Skin Tribology." In Technological Adoption and Trends in Health Sciences Teaching, Learning, and Practice, 1–25. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-7998-8871-0.ch001.

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The purpose of this chapter is to give an outline and interpretation of the experimental findings for the in vivo and in laboratory experiments about frictional behavior of human skin. The scientific literature framework will be illustrated, and the different factors affecting human skin's friction behavior will be explored considering the theoretical aspects which were summarized and discussed connected to the friction mechanisms, with an emphasis on the analysis of the adhesion and deformation component in different skin conditions. Moreover, the chapter highlighted some technical concepts considering different techniques and measurement parameters used to investigate the friction of human skin in different human body parts and in different contact conditions.
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Seidenari, Stefania. "Ultrasound B-Mode Imaging and In Vivo Structure Analysis." In Handbook of Non-Invasive Methods and the Skin, Second Edition, 493–505. CRC Press, 2006. http://dx.doi.org/10.3109/9781420003307-69.

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Zhao, Jianhua, Harvey Lui, David I., and Haishan Zeng. "Real-Time Raman Spectroscopy for Noninvasive in vivo Skin Analysis and Diagnosis." In New Developments in Biomedical Engineering. InTech, 2010. http://dx.doi.org/10.5772/7603.

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Meyer, Lars, and Juergen Lademann. "Application of In Vivo Scanning Microscopy for Skin Analysis in Dermatology and Cosmetology." In Dermatologic, Cosmeceutic, and Cosmetic Development, 487–96. CRC Press, 2007. http://dx.doi.org/10.3109/9780849375903-30.

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Bleve, Mariella, Franca Pavanetto, and Paola Perugini. "Solid Lipid Nanoparticles: Technological Developments and in Vivo Techniques to Evaluate Their Interaction with the Skin." In Progress in Molecular and Environmental Bioengineering - From Analysis and Modeling to Technology Applications. InTech, 2011. http://dx.doi.org/10.5772/19290.

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Conference papers on the topic "In-vivo Skin analysis"

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Riemann, I., M. Schwarz, F. Stracke, A. Ehlers, E. Dimitrow, M. Kaatz, K. König, and R. Le Harzic. "New developments in two-photon analysis of human skin in vivo." In SPIE LASE: Lasers and Applications in Science and Engineering, edited by Joseph Neev, Stefan Nolte, Alexander Heisterkamp, and Rick P. Trebino. SPIE, 2009. http://dx.doi.org/10.1117/12.808770.

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Knight, Anna E., Adam B. Pely, Felix Q. Jin, Adela R. Cardones, Mark L. Palmeri, and Kathryn R. Nightingale. "Analysis of Factors Affecting Shear Wave Speed in in vivo Skin." In 2019 IEEE International Ultrasonics Symposium (IUS). IEEE, 2019. http://dx.doi.org/10.1109/ultsym.2019.8925965.

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Musumeci, Francesco, Luca Lanzanò, Simona Privitera, Salvatore Tudisco, and Agata Scordino. "Spectral analysis of photoinduced delayed luminescence from human skin in vivo." In European Conference on Biomedical Optics. Washington, D.C.: OSA, 2007. http://dx.doi.org/10.1364/ecbo.2007.6633_55.

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Bevilacqua, A., A. Gherardi, and R. Guerrieri. "In Vivo Quantitative Evaluation of Skin Ageing by Capacitance Image Analysis." In 2005 Seventh IEEE Workshops on Applications of Computer Vision (WACV/MOTION'05). IEEE, 2005. http://dx.doi.org/10.1109/acvmot.2005.61.

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Li, Lisa, and Russell A. Chipman. "Short-wave infrared Mueller matrices and polarization parameters for in vivo skin surface reflectance." In Polarization: Measurement, Analysis, and Remote Sensing XIII, edited by David B. Chenault and Dennis H. Goldstein. SPIE, 2018. http://dx.doi.org/10.1117/12.2305279.

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Mogilevych, Borys, Laurita dos Santos, Joao L. Rangel, Karen J. S. Grancianinov, Mariane P. Sousa, and Airton A. Martin. "Analysis of the in vivo confocal Raman spectral variability in human skin." In SPIE Biophotonics South America, edited by Cristina Kurachi, Katarina Svanberg, Bruce J. Tromberg, and Vanderlei S. Bagnato. SPIE, 2015. http://dx.doi.org/10.1117/12.2181030.

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Musumeci, Francesco, Luca Lanzanò, Simona Privitera, Salvatore Tudisco, and Agata Scordino. "Spectral analysis of photo-induced delayed luminescence from human skin in vivo." In European Conference on Biomedical Optics, edited by Jürgen Popp and Gert von Bally. SPIE, 2007. http://dx.doi.org/10.1117/12.727696.

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Yow, Ai Ping, Jun Cheng, Annan Li, Ruchir Srivastava, Jiang Liu, Damon Wing Kee Wong, and Hong Liang Tey. "Automated in vivo 3D high-definition optical coherence tomography skin analysis system." In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2016. http://dx.doi.org/10.1109/embc.2016.7591579.

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Sakai, Shingo, Masahiro Yamanari, Yiheng Lim, Shuichi Makita, Noriaki Nakagawa, and Yoshiaki Yasuno. "In vivo analysis of human skin anisotropy by polarization-sensitive optical coherence tomography." In SPIE BiOS. SPIE, 2011. http://dx.doi.org/10.1117/12.873501.

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Tran, Sophie, Sergey Zaytsev, Viktoriya Charykova, Munira Yusupova, Alexey Bashkatov, Elina Genina, Valery Tuchin, Walter Blondel, and Marine Amouroux. "Analysis of image features for the characterization of skin optical clearing kinetics performed on in vivo and ex vivo human skin using Linefield-Confocal Optical Coherence Tomography (LC-OCT)." In Optics in Health Care and Biomedical Optics X, edited by Qingming Luo, Xingde Li, Ying Gu, and Dan Zhu. SPIE, 2020. http://dx.doi.org/10.1117/12.2575173.

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