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1

Paul, Jennings. In vitro toxicology systems. New York, NY: Humana Press, 2014.

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2

In vitro neurotoxicology: Methods and protocols. New York: Humana/Springer, 2011.

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3

Joint American-Swiss Seminar on Alternative Embryotoxicity and Teratogenicity Tests (1984 Zurich, Switzerland). In vitro embryotoxicity and teratogenicity tests: Joint American-Swiss Seminar on Alternative Embryotoxicity and Teratogenicity Tests, Zürich, November 12, 1984. Edited by Homburger Freddy and Goldberg Alan M. Basel, Switzerland: New York, 1985.

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4

Atterwill, C. K., and C. E. Steele. In vitro methods in toxicology. Cambridge: Cambridge University Press, 2009.

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5

O’Hare, Sheila, and Chris K. Atterwill, eds. In Vitro Toxicity Testing Protocols. Totowa, NJ: Humana Press, 1995. http://dx.doi.org/10.1385/0896032825.

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6

Clarke, Hilary. In vivo and in vitro studies on cyclosporine-induced nephrotoxicity. Dublin: University College Dublin, 1997.

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7

New technologies for toxicity testing. New York, N.Y: Springer Science+Business Media, 2012.

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8

International Group of National Associations of Agrochemical Manufacturers. GIFAP position paper on acute toxicity tests. Bruxelles, Belgique: International Group of National Associations of Manufacturers of Agrochemical Products, 1988.

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9

Rosen, Shara. The worldwide market for in vitro diagnostic tests. Edited by Heffner Steven and Kalorama Information LLC. 4th ed. New York, NY: Kalorama Information, 2004.

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10

Persoone, G. Cost-analysis of five current aquatic toxicity tests. Luxembourg: Commission of theEuropean Communities, 1988.

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11

Baker, John R. Instream tests for toxicity persistence from heavy metals. Las Vegas, NV: U.S. Environmental Protection Agency, Environmental Monitoring Systems Laboratory, 1985.

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12

Rhône-Poulenc Rorer Round Table Conference (6th 1990 Les Pensières, France). In vitro methods in toxicology. London: Academic, 1992.

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13

Introduction to in vitro cytotoxicology: Mechanisms and methods. Boca Raton: CRC Press, 1994.

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14

Hunn, Joseph B. History of acute toxicity tests with fish, 1863-1987. LaCrosse, Wis. (P.O. Box 818, LaCrosse 54602): U.S. Fish and Wildlife Service, National Fisheries Research Center--LaCrosse, 1989.

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15

Brauer, Samuel. The market for in vitro toxicology testing. Norwalk, CT: Business Communications Co., 2003.

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16

Brauer, Samuel. The market for in vitro toxicology testing. Norwalk, CT: Business Communications Co., 1997.

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17

Agency, Illinois Environmental Protection. IEPA mobile laboratory screening tests information sheet. Springfield, IL]: Illinois Environmental Protection Agency, Division of Laboratories, 1993.

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18

Gerhard, Beck Ernst, Bignon J, and North Atlantic Treaty Organization. Scientific Affairs Division., eds. In vitro effects of mineral dusts: Third international workshop. Berlin: Published in cooperation with NATO Scientific Affairs Division [by] Springer-Verlag, 1985.

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19

Stanley, Lesley A. Molecular and cellular toxicology: An introduction. Chichester, West Sussex, UK: John Wiley & Sons Inc., 2014.

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20

Sandbacka, Maria. Gill epithelial cells as in vitro models in aquatic toxicology. Åbo: Åbo Academi University Press, 2001.

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21

Kreger, Michael D. The LD50 (median lethal dose) and LC50 (median lethal concentration) toxicity tests. Beltsville, Md: National Agricultural Library, 1992.

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22

Kreger, Michael D. The LD50 (median lethal dose) and LC50 (median lethal concentration) toxicity tests. Beltsville, Md: National Agricultural Library, 1992.

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23

Kreger, Michael D. The LD50 (median lethal dose) and LC50 (median lethal concentration) toxicity tests. Beltsville, Md: National Agricultural Library, 1992.

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24

Klemm, Donald J. Manual for the evaluation of laboratories performing aquatic toxicity tests. Cincinnati, Ohio: Environmental Monitoring Systems Laboratory, Office of Modeling, Monitoring Systems, and Quality Assurance, Office of Research and Development, U.S. Environmental Protection Agency, 1991.

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25

Agency, OECD Nuclear Energy. Acute oral toxicity: Up-and-down procedure (UDP). Paris: Organisation for Economic Co-operation and Development, 2006.

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26

Lodola, Alberto, and Jeanne Stadler. Pharmaceutical toxicology in practice: A guide for non-clinical development. Hoboken, N.J: Wiley, 2011.

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27

National Toxicology Program (U.S.). NTP technical report on the toxicology and carcinogenesis studies of titanocene dichloride (CAS no. 1271-19-8) in F344/N rats (gavage studies). Research Triangle Park, NC: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1991.

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28

Gann, Richard G. Smoke component yields from room-scale fire tests. Gaithersburg, MD]: U.S. Dept. of Commerce, Technology Administration, National Institute of Standards and Technology, 2003.

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29

Dwyer, F. James. Assessing contaminant sensitivity of endangered and threatened species: Effluent toxicity tests. Washington, D.C: United States Environmental Protection Agency, Office of Research and Development, 1999.

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30

Zajdlik, B. A. Report on biological toxicity tests using pollution gradient studies - Sydney Harbor. [Ottawa]: Environment Canada, Marine Environment Division, 2000.

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31

Clingerman, Karen J. The LD50 (median lethal dose) and LC50 (median lethal concentration) toxicity tests, January 1980 - August 1990. Beltsville, Md: National Agricultural Library, 1990.

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32

Clingerman, Karen J. The LD50 (median lethal dose) and LC50 (median lethal concentration) toxicity tests, January 1980 - August 1990. Beltsville, Md: National Agricultural Library, 1990.

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33

Clingerman, Karen J. The LD50 (median lethal dose) and LC50 (median lethal concentration) toxicity tests, January 1980 - August 1990. Beltsville, Md: National Agricultural Library, 1990.

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34

World Congress on Alternatives and Animal Use in the Life Sciences (1st 1993 Baltimore, Md.). World Congress on Alternatives and Animal Use in the Life Sciences: Education, research, testing. Edited by Goldberg Alan M, Zutphen, L. F. M. van, and Principe Marilyn L. New York, NY: Mary Ann Liebert, 1995.

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35

Sheila, O'Hare, and Atterwill C. K, eds. In vitro toxicity testing protocols. Totowa, N.J: Humana Press, 1995.

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36

In Vitro Toxicology. 2nd ed. CRC, 2000.

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37

Tyson, Charles A. Methods in Toxicology: Part A : In Vitro Biological Systems (Methods in Toxicology). Academic Press, 1993.

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38

A, Tyson Charles, and Frazier John M, eds. Methods in toxicology. San Diego, Calif: Academic Press, 1993.

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39

(Editor), Jose V. Castell, and Maria Jose Gmez-Lechn (Editor), eds. In Vitro Methods in Pharmaceutical Research. Academic Press, 1997.

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40

Luz, Claudio, and United States. Environmental Protection Agency, eds. Implementing in vitro test models in the hazard identification and risk assessment process. [Washington, D.C: U.S. Environmental Protection Agency, 1992.

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41

Iversen, Les. 5. Making new medicines. Oxford University Press, 2016. http://dx.doi.org/10.1093/actrade/9780198745792.003.0005.

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‘Making new medicines’ outlines the process of developing and marketing new drugs. Advanced techniques provide scientists with many potential receptor targets. Compounds which may affect the target are tested in vitro. If they appear to work further tests are carried out, increasing in complexity from cells to whole organisms. Animal trials help forecast toxicity and determine dosages. Finally, three-phase clinical trials occur in humans. Pharmaceutical companies then submit their data to the government for approval, before the drug can be sold. The lengthy and expensive process often results in high drug prices. A relatively new class of medicines—monoclonal antibodies—is having a major impact in treating hitherto untreatable conditions.
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42

W, Pentreath V., ed. Neurotoxicology in vitro. London: Taylor & Francis, 1999.

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43

M, Goldberg Alan, Principe Marilyn L, and Johns Hopkins Center for Alternatives to Animal Testing. Symposium., eds. In vitro toxicology: New directions. New York: Mary Ann Liebert, Inc., 1989.

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44

Evelyn, Tiffany-Castiglioni, ed. In vitro neurotoxicology: Principles and challenges. Totowa, N.J: Humana Press, 2004.

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45

M, Frazier John, ed. In vitro toxicity testing: Applications to safety evaluation. New York: Marcel Dekker, 1992.

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46

M, Goldberg Alan, Principe Marilyn L, and Johns Hopkins Center for Alternatives to Animal Testing. (6th : 1989 : Baltimore, Md.), eds. In vitro toxicology: New directions. New York: M.A. Liebert, 1989.

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47

M, Goldberg Alan, Principe Marilyn L, and Johns Hopkins Center for Alternatives to Animal Testing., eds. Progress in in vitro toxicology. New York: Mary Ann Liebert, Inc., Publishers, 1988.

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48

In vitro toxicology: Approaches to validation. New York, NY: M.A. Liebert, 1987.

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49

1948-, Gad Shayne C., ed. In vitro toxicology. New York: Raven Press, 1994.

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50

K, Atterwill C., and Steele C. E, eds. In vitro methods in toxicology. Cambridge: Cambridge University Press, 1987.

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