Academic literature on the topic 'Immunotherapy'
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Journal articles on the topic "Immunotherapy"
Bakulesh, Khamar. "Immunotherapy of Bladder Cancer." Cancer Medicine Journal 3, no. 2 (December 31, 2020): 49–62. http://dx.doi.org/10.46619/cmj.2020.3-1020.
Full textKim, Edwin H., and Arvil Wesley Burks. "Food allergy immunotherapy: Oral immunotherapy and epicutaneous immunotherapy." Allergy 75, no. 6 (February 28, 2020): 1337–46. http://dx.doi.org/10.1111/all.14220.
Full textFay, Emily K., and Julie N. Graff. "Immunotherapy in Prostate Cancer." Cancers 12, no. 7 (July 1, 2020): 1752. http://dx.doi.org/10.3390/cancers12071752.
Full textBintintan, Vasile, Claudia Burz, Irena Pintea, Adriana Muntean, Diana Deleanu, Iulia Lupan, and Gabriel Samasca. "Predictive Factors of Immunotherapy in Gastric Cancer: A 2024 Update." Diagnostics 14, no. 12 (June 13, 2024): 1247. http://dx.doi.org/10.3390/diagnostics14121247.
Full textNelson, Harold S., Melina Makatsori, and Moises A. Calderon. "Subcutaneous Immunotherapy and Sublingual Immunotherapy." Immunology and Allergy Clinics of North America 36, no. 1 (February 2016): 13–24. http://dx.doi.org/10.1016/j.iac.2015.08.005.
Full textSveikata, Lukas, Andreas Charidimou, and Anand Viswanathan. "Vessels Sing Their ARIAs: The Role of Vascular Amyloid in the Age of Aducanumab." Stroke 53, no. 1 (January 2022): 298–302. http://dx.doi.org/10.1161/strokeaha.121.036873.
Full textS V S, Gulakavarapu, Narapaneni Sravanthi, Praneeth Ulavala, and S. Chandrababu. "Immunotherapy and the Management of Allergies: An Overview of Monoclonal Antibody Therapy and Allergen Immunotherapy." International Journal of Science and Research (IJSR) 12, no. 9 (September 5, 2023): 1051–53. http://dx.doi.org/10.21275/mr23911124247.
Full textShi, Junhan. "Applications of immune checkpoint inhibitors (ICIs) in the medical fields." Highlights in Science, Engineering and Technology 36 (March 21, 2023): 321–30. http://dx.doi.org/10.54097/hset.v36i.5698.
Full textGillespy, Kristen, Margie D. Dixon, and Rebecca D. Pentz. "Communication about immunotherapy: Barriers and information to discuss." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 6543. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.6543.
Full text&NA;. "Immunotherapy." Reactions Weekly &NA;, no. 548 (April 1995): 8. http://dx.doi.org/10.2165/00128415-199505480-00029.
Full textDissertations / Theses on the topic "Immunotherapy"
Dadi, C. N. "Cancer immunotherapy." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/40532.
Full textFerrell, Melissa Leann. "Sublingual Immunotherapy." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/565918.
Full textWalker, Samantha Mary. "Immunotherapy for summer hayfever." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248036.
Full textMichael, Agnieszka. "Genetic immunotherapy for cancer." Thesis, St George's, University of London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437318.
Full textKwan, Byron H. (Byron Hua). "Integrin-targeted cancer immunotherapy." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104220.
Full textCataloged from PDF version of thesis.
Includes bibliographical references.
Integrins are a family of heterodimeric cell surface receptors that are functionally important for cell adhesion, migration and proliferation. Certain integrins, especially those that are known to recognize the arginine-glycine-aspartate (RGD) motif, are heavily overexpressed in many cancers relative to healthy tissue, making them attractive targets for therapeutic intervention. However, prior attempts to antagonize these integrins as a cancer therapy have all failed in the clinic. In this thesis, we instead exploit integrins as a target tumor antigen in the context of immunotherapy. The engineered cysteine knot peptide, 2.5F, is highly crossreactive and capable of recognizing multiple RGD-binding integrins. Our initial attempts to utilize this binder as a targeting moiety for delivering IL-2 as an immunocytokine failed. Mathematical modeling results indicated that immunocytokines, unless adhering to specific design criteria, are unlikely to benefit from targeting and may actually exhibit limited efficacy. Therefore, we "deconstructed" this immunocytokine into its functional parts: extended half-life IL-2 and 2.5F-Fc, the antibody-like construct directed against RGD-binding integrins. This combination immunotherapeutic approach was able to synergistically control tumor growth in three syngeneic murine models of cancer, including durable cures and development of immunological memory. Contrary to prior attempts at integrin-targeting, the mechanism of action was independent of functional integrin antagonism, including effects on angiogenesis and tumor proliferation. In fact, efficacy of this therapy depended solely upon the adaptive and innate arms of immunity, specifically CD8+ T cells, macrophages, and dendritic cells. Furthermore, checkpoint blockade, the gold standard for immunotherapy to date, can further enhance the efficacy of this therapeutic approach. This signifies that the combination of IL-2 and 2.5F-Fc exerts a distinct, yet complementary immune response that opens the door for clinical translation.
by Byron H. Kwan.
Ph. D.
Harrison, Simon James. "Immunotherapy in multiple myeloma." Thesis, University of Glasgow, 2005. http://theses.gla.ac.uk/1054/.
Full textJain, Renu Zaghouani Habib. "Immunotherapy for autoimmune diabetes." Diss., Columbia, Mo. : University of Missouri-Columbia, 2008. http://hdl.handle.net/10355/6869.
Full textChampiat, Stéphane. "Caractérisation clinique et biologique de l’hyperprogression tumorale lors du blocage de la voie PD-1/PD-L1." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS040.
Full textImmune checkpoint blocking antibodies are profoundly changing the management of patients with cancer. At the forefront of this novel anticancer agent class, anti-PD-1/PD-L1 antibodies can exhibit a significant activity by restoring an efficient antitumor T-cell response. As a result, these agents are now approved in various tumor types such as melanoma, squamous, and nonsquamous non–small cell lung cancer (NSCLC), renal cell carcinoma (RCC), head and neck squamous cell carcinoma (HNSCC) or bladder cancer. Interestingly, these new immunotherapies also result in novel tumor response patterns such as delayed tumor responses or pseudoprogressions. As experience grows with these therapeutics, anecdotal reports are relating rapid disease progressions, which could suggest that immune checkpoint blockade may have a deleterious effect by accelerating the disease in a subset of patients. This thesis work has made it possible to characterize clinically and biologically this phenomenon of accelerated tumor growth under anti-checkpoint immunotherapy, which we have defined as “hyperprogressive disease” (HPD). Transcriptomic analysis of tumour samples from these patients suggested a specific role for the myeloid environment
Bracher, Marguerite. "IgE in immunotherapy of cancer." Thesis, King's College London (University of London), 2006. https://kclpure.kcl.ac.uk/portal/en/theses/ige-in-immunotherapy-of-cancer(08abceea-54a8-436c-9504-24742d57538d).html.
Full textGraff, Christilyn Paula. "Antibody engineering for tumor immunotherapy." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/29279.
Full textVita.
Includes bibliographical references (leaves 130-140).
Antibodies have been used as cancer therapeutics for several decades. One area in which this therapy may be improved is the retention time of antibody in the tumor relative to normal tissue. In this Thesis, we have attempted to elucidate the mechanisms that are most influential to improving antibodies as cancer therapeutics. Carcinoembryonic antigen (CEA) has long been identified as a tumor-associated antigen. CEA is also quite stable, with a cell-surface shedding half-life of approximately 7 days. Directed evolution methodology has been utilized to design an antibody fragment with properties that would improve tumor retention. Specifically, antibody engineering methods were used to produce a humanized, extremely high affinity and stable single chain antibody fragment (scFv) against CEA. Several mutant scFv libraries were constructed and screened against soluble CEA with yeast surface display and fluorescent activated cell sorting (FACS). A series of antibodies were engineered that span three orders of magnitude in off-rate improvement. These antibody fragments show excellent stability at physiologically relevant temperatures. In addition, soluble protein expression levels were greatly improved. The final product has a dissociation half-life of approximately 7 days, currently the longest engineered half-life of an scFv against a tumor-associated antigen. Binding and diffusion in micrometastases was also modeled to gain an improved understanding of the quantitative interplay among the rate processes of diffusion, binding, degradation, and plasma clearance in tumor microspheroids.
(cont.) Modeling studies illuminated the importance of targeting stable tumor-associated antigens. The elimination rate of the antigen was of critical importance to the change in the therapeutic effect of antibodies with increasing affinity. The significance of this result in the context of previous experimental studies will be discussed. By affinity maturing an antibody with a dissociation half-life equal to the turnover half-life of the antigen, we have engineered an antibody with effectively irreversible binding to CEA. Differences in retention for the series of scFvs will thus be dominated by the off-rate of the antibody and not the half-life of CEA. With this in mind, the molecules designed in this study can be used to reconcile the issue of affinity's impact on efficacy in tumor therapy.
by Christilyn Paula Graff.
Ph.D.
Books on the topic "Immunotherapy"
Naing, Aung, and Joud Hajjar, eds. Immunotherapy. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79308-1.
Full textNaing, Aung, and Joud Hajjar, eds. Immunotherapy. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-53156-4.
Full textNaing, Aung, and Joud Hajjar, eds. Immunotherapy. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-02505-2.
Full textNaing, Aung, and Joud Hajjar, eds. Immunotherapy. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41008-7.
Full textP, Allison James, and Dranoff Glenn, eds. Cancer immunotherapy. Amsterdam: Elsevier Academic Press, 2006.
Find full textLudewig, Burkhard, and Matthias W. Hoffmann. Adoptive Immunotherapy. New Jersey: Humana Press, 2004. http://dx.doi.org/10.1385/1592598625.
Full textCuriel, Tyler J., ed. Cancer Immunotherapy. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-4732-0.
Full textF, Lockey Richard, and Bukantz Samuel C, eds. Allergen immunotherapy. New York: M. Dekker, 1991.
Find full textSiciliano, Velia, and Francesca Ceroni, eds. Cancer Immunotherapy. New York, NY: Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3593-3.
Full textLiau, Linda M., Donald P. Becker, Timothy F. Cloughesy, and Darell D. Bigner. Brain Tumor Immunotherapy. New Jersey: Humana Press, 2000. http://dx.doi.org/10.1385/1592590357.
Full textBook chapters on the topic "Immunotherapy"
Volc, Sebastian, Kamran Ghoreschi, and Hui Shen. "Immunotherapy." In Practical Immunodermatology, 367–81. Dordrecht: Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-024-0902-4_15.
Full textdel Bufalo, Francesca, and Franco Locatelli. "Immunotherapy." In Neuroblastoma, 237–69. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-18396-7_13.
Full textMalmgren, Richard A. "Immunotherapy." In Cancer Management in Man, 270–80. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-2536-6_22.
Full textCarroll, Marilyn E., Peter A. Santi, Joseph Zohar, Thomas R. E. Barnes, Peter Verheart, Per Svenningsson, Per E. Andrén, et al. "Immunotherapy." In Encyclopedia of Psychopharmacology, 618. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_3314.
Full textSeifert, Steven A., and Brandon J. Warrick. "Immunotherapy." In Critical Care Toxicology, 1–15. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-20790-2_176-2.
Full textDorval, Th. "Immunotherapy." In Bone Metastases, 43–48. London: Springer London, 2002. http://dx.doi.org/10.1007/978-1-4471-3251-6_4.
Full textDabski, Krzysztof, and Frederick Helm. "Immunotherapy." In Skin Cancer, 363–77. New York, NY: Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3790-7_28.
Full textJasmin, Claude, T. A. Plunkett, and D. W. Miles. "Immunotherapy." In Textbook of Bone Metastases, 313–22. Chichester, UK: John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/0470011610.ch24.
Full textNahler, Gerhard. "immunotherapy." In Dictionary of Pharmaceutical Medicine, 89. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_671.
Full textTur, Mehmet Kemal, and Stefan Barth. "Immunotherapy." In Encyclopedia of Cancer, 1–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27841-9_3014-2.
Full textConference papers on the topic "Immunotherapy"
Fu, D., and Z. Chen. "Plasma Immunotherapy for Biomedical Applications." In 2024 IEEE International Conference on Plasma Science (ICOPS), 1. IEEE, 2024. http://dx.doi.org/10.1109/icops58192.2024.10627467.
Full textMazur, Martyna, Maria Baczewska, Paulina Laskowska, Michał Gontarz, and Michał Ziemczonok. "Integrating Digital Holographic Microscopy with Data Analysis for Monitoring Lymphocyte Activation in Cellular Immunotherapy." In Digital Holography and Three-Dimensional Imaging, W4A.21. Washington, D.C.: Optica Publishing Group, 2024. http://dx.doi.org/10.1364/dh.2024.w4a.21.
Full text"Tumor Immunotherapy." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.139.
Full textNaylor, Mark F., Kaili Liu, Ashley R. Hoover, and Wei R. Chen. "Biophotonics-based immunotherapy and checkpoint-based immunotherapy for cancer." In Biophotonics and Immune Responses XVI, edited by Wei R. Chen. SPIE, 2021. http://dx.doi.org/10.1117/12.2585180.
Full textShah, D. J., and C. M. Lo Cascio. "Immunotherapy Induced Pneumonitis." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2115.
Full textLe, Anh Trang Nguyen, and Larysa Baraban. "Nanoelectronics for immunotherapy." In 2023 IEEE Nanotechnology Materials and Devices Conference (NMDC). IEEE, 2023. http://dx.doi.org/10.1109/nmdc57951.2023.10344017.
Full textGupta, A., G. Singh, and H. Jain. "Immunotherapy Induced Encephalitis." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5698.
Full textRoth, L. "Novel agents beyond Immunotherapy." In ISCAYAHL 2020. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1701868.
Full textLozzo, Eneida Da, Edvaldo da Silva Trindade, Carolina De Oliveira, and Dorly de Buchi. "Homeopathic Immunotherapy against Cancer." In HRI London 2019—Cutting Edge Research in Homeopathy: Presentation Abstracts. The Faculty of Homeopathy, 2020. http://dx.doi.org/10.1055/s-0040-1702103.
Full textWang, Zihan. "Overview of Cancer Immunotherapy." In ICBBE '20: 2020 7th International Conference on Biomedical and Bioinformatics Engineering. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3444884.3444919.
Full textReports on the topic "Immunotherapy"
Chen, Ru, Yao Sun, and Guoqi Sima. Comparative efficacy and tolerance of intralymphatic, subcutaneous and sublingual immunotherapy for pollen-induced allergic rhinitis: a network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2022. http://dx.doi.org/10.37766/inplasy2022.1.0078.
Full textSuleyman, Narin, Robert Hughes, Jeremy Teoh, Anand Sharma, and Nikhil Vasdev. Immunotherapy in urological malignancy. BJUI Knowledge, September 2021. http://dx.doi.org/10.18591/bjuik.0735.
Full textJadhav, Avadhoot. Towards a Universal Immunotherapy. New Science, September 2022. http://dx.doi.org/10.56416/591plq.
Full textLubaroff, David M. Vaccine Immunotherapy for Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, May 2008. http://dx.doi.org/10.21236/ada484307.
Full textLee, Peter P. Integrated Immunotherapy for Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2014. http://dx.doi.org/10.21236/ada613328.
Full textLubaroff, David M. Vaccine Immunotherapy for Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, May 2010. http://dx.doi.org/10.21236/ada535354.
Full textLubaroff, David M. Vaccine Immunotherapy for Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, May 2009. http://dx.doi.org/10.21236/ada509761.
Full textRupprecht, Ruth M. Immunotherapy of Congenital SIV Infection. Fort Belvoir, VA: Defense Technical Information Center, October 1998. http://dx.doi.org/10.21236/ada358457.
Full textLee, Peter P. Integrated Immunotherapy for Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2013. http://dx.doi.org/10.21236/ada591526.
Full textLubaroff, David. Vaccine Immunotherapy for Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, July 2006. http://dx.doi.org/10.21236/ada462829.
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