Academic literature on the topic 'Immunotechnology'

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Journal articles on the topic "Immunotechnology"

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Haynes, SJ. "Immunotechnology." Biochemical Education 22, no. 2 (April 1994): 108. http://dx.doi.org/10.1016/0307-4412(94)90114-7.

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Whiteside, Theresa L. "Immunotechnology." Clinical Immunology Newsletter 8, no. 1 (January 1987): 13–15. http://dx.doi.org/10.1016/0197-1859(87)90005-7.

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Ohlin, Mats, and Carl A. K. Borrebaeck. "Immunotechnology." Immunology Today 15, no. 10 (October 1994): 499–500. http://dx.doi.org/10.1016/0167-5699(94)90200-3.

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Cáceres, Susana Arlet, Diana Pérez- Etcheverry, Silvina Rossi-Assandri, and Iris Miraballes-Martínez. "Studies about polymers, their interactions with the immune system and applications in immunotechnology in Uruguay: a systematic review / Estudos sobre polímeros, suas interações com o sistema imunológico e aplicações em imunotecnologia no Uruguai: uma revisão sistemática." BRAZILIAN APPLIED SCIENCE REVIEW 6, no. 4 (July 21, 2022): 1317–39. http://dx.doi.org/10.34115/basrv6n4-008.

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The aim of the present work was to review, for the first time, articles published by researchers from Uruguay describing the effect of polymers on the vertebrate immune system or the use of polymers in immunotechnology. Databases and the national registry were searched. The first articles included were published in 1993. Several groups of articles were defined for better understanding: 1) polymeric molecules from parasites and pathogenic bacteria; 2) studies on the use of polymers with adjuvant properties; 3) use of synthetic polymers in immunotechnology development and 4) use of polymers in drug delivery systems targeting the immune system. Various approaches have been explored for applications related to animal and human health. Examples include the identification of molecules suitable as antigens for vaccines and the use of adjuvants in vaccines. Immunoassays for the detection and quantification of antibodies or antigens and a cancer therapy system have been identified.
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Larrick, James W., Robert F. Balint, and Douglas C. Youvan. "Green fluorescent protein: untapped potential in immunotechnology." Immunotechnology 1, no. 2 (August 1995): 83–86. http://dx.doi.org/10.1016/1380-2933(95)00011-9.

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Pepose, Jay S. "Application of Immunotechnology to the Diagnosis of Ocular Viral Infections." Cornea 6, no. 1 (1987): 69. http://dx.doi.org/10.1097/00003226-198706010-00068.

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Howgrave‐Graham, A. R., A. J. L. Macario, and F. M. Wallis. "Quantitative analysis and mapping of micro‐organisms in anaerobic digester granules using a combination of transmission electron microscopy with immunotechnology." Journal of Applied Microbiology 83, no. 5 (November 1997): 587–95. http://dx.doi.org/10.1046/j.1365-2672.1997.00269.x.

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"Single-chain Fv immunotechnology." Immunotechnology 2, no. 4 (November 1996): 269–70. http://dx.doi.org/10.1016/s1380-2933(97)88989-0.

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"Now Incorporating Immunotechnology Guide for Authors." Journal of Immunological Methods 258, no. 1-2 (December 2001): 201–4. http://dx.doi.org/10.1016/s0022-1759(01)00518-x.

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"Now Incorporating Immunotechnology Guide for Authors." Journal of Immunological Methods 253 (October 2001): 57–60. http://dx.doi.org/10.1016/s0022-1759(01)00532-4.

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Dissertations / Theses on the topic "Immunotechnology"

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Rönnmark, Jenny. "Affibody ligands in immunotechnology applications." Doctoral thesis, KTH, Biotechnology, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3369.

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This thesis describes the development and use ofnon-immunoglobulin affinity proteins denoted affibodies asalternatives to antibodies in different immunotechnologyapplications. A 58 aa IgG Fc binding three-helix bundle domainZ, derived from staphylococcal protein A has been used asframework for library constructions, in which the face of themolecule involved in the native binding activity has beenengineered by combinatorial protein engineering. Recruting 13surface-located positions for simultanenous substitutionmutagenesis, using degenerated oligonucleotides for libraryassembly at the genetic level, two libraries differing in thechoice of codons were constructed to serve as general sourcesof novel affinity proteins. The libraries were adapted fordisplay onE. colifilamentous phage particles allowingin vitroselection of desired variants capable ofbinding a given target molecule. In selections using human IgAas target, several new IgA specific affibodies could beidentified. One variant ZIgA1, was further investigated and showed binding toboth IgA1 and IgA2 human subclasses as well as to secretoryIgA. This variant was further demonstrated uesful as ligand inaffinity chromatography purification for recovery of IgA fromdifferent samples including unconditioned human plasma.Affibodies of different specificities were also fused to otherprotein domains to construct fusion proteins of relevance forimmunotechnology applications. Using Fc of human IgG as genefusion partner, "artificial antbodies" could be produced inE. colias homodimeic proteins, where the antigenbinding was confered by N-terminally positioned affibodymoieties of different valencies. One area of application forthis type of constructs was demonstrated through specificdetection of the target protein by Western blotting. Exploitingthe uncomplicated structure of affibody affinity proteins, genefusions between affibodies and the homotetrameric reporterenzyme β-galactosidase were constructed, which could beproduced as soluble proteins intracellularly inE. coli. The potential use of such recombinantimmunoconjugates in immunotechnology was demonstrated in ELISAdot-blot and immunohistochemistry, where in the latter case IgAdepositions in the glomeruli of a human kidney biopsy could bespecfically detected with low background staining ofsurrounding tissues. In a novel format for sandwich ELISA, thepossible advantage of the bacterial origin of the affibodyclass of affinity proteins was investigated. As a means tocircumvent problems associated with the presence of humanheterophilic antibodies in serum, causing bakground signals dueto analyte-independent crosslinking of standard capture anddetection antibody reagents, assay formats based oncombinations of antibody and affibody reagents for capture anddetection were investigated and found to be of potentialuse.

Keywords:phage display, combinatorial, affinity, IgAligand, immunohistochemistry, affibody-fusions

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Wei, Jiewei School of Biotechnology &amp Biomolecular Science UNSW. "Construction, expression and characterisation of a human anti-CD48 monoclonal antibody." Awarded by:University of New South Wales. School of Biotechnology and Biomolecular Science, 2006. http://handle.unsw.edu.au/1959.4/27413.

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Monoclonal antibodies and antibody-based entities are a major class of therapeutic proteins. The surge in development of monoclonal antibodies is predominantly due to the utilization of technologies for producing fully human antibodies, namely phage display and transgenic mice with human humoral immune systems. Human CD48, a cell-surface adhesion molecule, is a potential tumor target for the treatment of white blood cell malignancies, principally leukemia and lymphoma. A truncated, secreted form of CD48 was expressed in CHO cells, and was shown to bind to existing anti- CD48 murine antibodies. A human anti-CD48 scFv antibody fragment, (designated scFv-N2A) was previously isolated using phage display technology from a synthetic human scFv immunoglobulin gene library. The scFv-N2A was reassembled as a human IgG1 monoclonal antibody (designated IgG1-N2A), expressed in CHO cells and the binding of IgG1-N2A to recombinant CD48 was confirmed by enzyme-linked immunosorbent assay, surface plasmon resonance and fluorescence activated cell sorting. IgG1-N2A binding to CD48 on Raji cells showed that the specificity of the human antibody for GPI-linked CD48 was conserved. In biological studies using a human lymphoma cell line (Raji), it was found that the IgG1-N2A antibody was able to induce potent growth inhibition, with a 68% reduction in viable cells. Furthermore, Raji cells treated with IgG1-N2A showed evidence of increased ethidium bromide uptake and cell shrinkage, which are characteristics associated with direct induction of apoptosis. The data suggests the novel human anti-CD48 IgG1-N2A monoclonal antibody can block proliferation and promote apoptosis of lymphoma cells, and therefore has potential as a lead antibody candidate for the treatment of white blood cell malignancies.
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Berggren, Christine. "Affinity biosensors based on a capacitive transducer." Lund : Lund University, 1998. http://catalog.hathitrust.org/api/volumes/oclc/68945028.html.

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Wemmer, Susan. "Expression and enigineering of recombinant antibodies against a heat-shock protein of Mycobacterium bovis." Pretoria : [s.n.], 2008. http://upetd.up.ac.za/thesis/available/etd-10212008-153754/.

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Books on the topic "Immunotechnology"

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1956-, Rogers Kim R., and Mulchandani Ashok 1956-, eds. Affinity biosensors: Techniques and protocols. Totowa, N.J: Humana Press, 1998.

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Federation of European Biochemical Societies. Meeting. Immunotechnology: Proceedings of the 21st Federation of European Biochemical Societies meeting, Dublin. Edited by Gosling J. P and Reen D. J. London: Portland Press, 1993.

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National Seminar on Emerging Trends at the Interface of Biotechnology (2007 Shahada, India). Biotechnology emerging trends. Edited by Sayyed Riyazali Z. Jodhpur: Scientific Publishers (India), 2009.

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National Seminar on Emerging Trends at the Interface of Biotechnology (2007 Shahada, India). Biotechnology emerging trends. Edited by Sayyed Riyazali Z. Jodhpur: Scientific Publishers (India), 2009.

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5

Kuhl, Phillips. Commercialization of antibody engineering. Burlington, Mass: Decision Resources, 1991.

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G, Dalgleish A., Albertini Alberto, and Paoletti Rodolfo, eds. The Impact of biotechnology on autoimmunity. Dordrecht: Kluwer Academic Publishers, 1994.

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C, Lo Benny K., ed. Antibody engineering: Methods and protocols. Totowa, N.J: Humana Press, 2004.

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The cell builders. Garden City, N.Y: Doubleday, 1986.

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9

Immunology and Immunotechnology. Oxford University Press, 2006.

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Moran, Anthony, and James P. Gosling. Immunotechnology: Principles, Concepts and Applications. John Wiley & Sons, 2008.

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Book chapters on the topic "Immunotechnology"

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Mandal, Santi M., and Debarati Paul. "Immunotechnology." In Automation and Basic Techniques in Medical Microbiology, 145–63. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2372-5_10.

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Shakeel, Qaiser, Rabia Tahir Bajwa, Ifrah Rashid, Hafiz Muhammad Usman Aslam, Yasir Iftikhar, Mustansar Mubeen, Guoqing Li, and Mingde Wu. "Immunotechnology for Plant Disease Detection." In Trends in Plant Disease Assessment, 145–65. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-5896-0_9.

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Anderson, D. P. "Immunotechnology and Viral Diseases of Fish." In Viruses of Lower Vertebrates, 463–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-83727-2_42.

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