Relevant bibliographies by topics / IMI 318

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'IMI 318'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "IMI 318"

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Ezugwu, E. O., K. A. Olajire, and Z. M. Wang. "Wear evaluation of a self-propelled rotary tool when machining titanium alloy IMI 318." Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture 216, no. 6 (June 1, 2002): 891–97. http://dx.doi.org/10.1243/095440502320193012.

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This paper presents results of a self-propelled rotary tool (SPRT) tipped with round uncoated carbide (WC-Co) inserts in the finish turning of titanium alloy IMI 318. SPRT inserts exhibited superior wear resistance to conventional round and rhomboid-shaped carbides as well as to the rhomboid-shaped physical vapour deposition (PVD) TiN-coated carbide inserts owing to the distribution of the cutting energy along the entire tool edge. The SPRT-tipped inserts suppressed thermally related wear mechanisms at higher speeds beyond the capability of conventional tools. Chipping was the dominant failure mode of the SPRT inserts, resulting from cyclically fluctuating thermal and mechanical shocks induced by the continuous shifting of the cutting edge during machining. A fitted exponential wear model revealed that about 97 per cent of the average flank wear rate of SPRT inserts can be attributed to the joint effect of speed, feed and inclination angle, ε. Tool performance was improved by increasing the inclination angle ε which resulted in a lower machining temperature on account of a higher rotary speed and a lower relative cutting speed during machining. Lower component forces were recorded with SPRT inserts because of the reduced amount of work done in chip formation and lower friction at the rake face.
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Raja, Shahzad G., Umberto Benedetto, Eman Alkizwini, Sapna Gupta, and Mohamed Amrani. "Propensity Score Adjusted Comparison of MIDCAB versus Full Sternotomy Left Anterior Descending Artery Revascularization." Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 10, no. 3 (May 2015): 174–78. http://dx.doi.org/10.1097/imi.0000000000000162.

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Objective Minimally invasive direct coronary artery bypass (MIDCAB) has been proposed as an attractive alternative to full sternotomy (FS) revascularization in isolated left anterior descending (LAD) artery disease not suitable for percutaneous coronary intervention. However, surgeons are still reluctant to perform MIDCAB owing to concerns about early and late outcomes. We aimed to compare short- and long-term outcomes after MIDCAB versus FS revascularization. Methods Prospectively collected data from institutional database were reviewed. Data for late mortality were obtained from the General Register Office. MIDCAB was performed in 318 patients, whereas 159 had FS, according to the surgeon's preference, among 477 patients with isolated LAD disease. Inverse propensity score weighting was used to estimate treatment effects on short- and long-term outcomes. Results In the propensity score-adjusted analysis, FS revascularization versus MIDCAB was associated increased rate of surgical site infection [4 (2.8%) versus 1 (0.7%); P = 0.04]. The 2 groups did not significantly differ with regard to other complications including operative mortality. Mean length of hospital stay was similar for the 2 groups. After a mean follow-up time of 6.2 years (interquartile range, 3.5–9.7 years), compared to MIDCAB, FS was not associated with an improved late survival (β coef, −1.42; standard error, 1.65; P = 0.39) or risk reduction for repeat revascularization (β coef, 1.22; standard error, 1.41; P = 0.15). Conclusions MIDCAB was associated with a trend toward better short-term outcomes and excellent long-term results comparable to FS revascularization. According to these findings, surgeons should not be reluctant to perform MIDCAB in isolated LAD disease.
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Dearnley, P. A., and A. N. Grearson. "Evaluation of principal wear mechanisms of cemented carbides and ceramics used for machining titanium alloy IMI 318." Materials Science and Technology 2, no. 1 (January 1986): 47–58. http://dx.doi.org/10.1179/mst.1986.2.1.47.

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REY DE CASTRO MUJICA, Jorge, Jimy ALVAREZ MAYORGA, and Angelo GAFFO LLONTOP. "Síntomas relacionados a trastornos del sueño en supuestos sanos que asisten a un centro de Atención Primaria de Salud." Revista Medica Herediana 16, no. 1 (December 19, 2012): 31. http://dx.doi.org/10.20453/rmh.v16i1.861.

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Objetivo: Evaluar los síntomas relacionados a trastornos del sueño en una población supuestamente sana. Material y Métodos: El estudio fue transversal y descriptivo en adultos supuestos sanos que asistieron a un centro de atención primaria de salud. Se confeccionó una encuesta auto administrada y validada por nosotros. La muestra final de 590 encuestados que corresponde al 28% de la población general de 17 ó más años que vive en el área de influencia. Resultados: Edad promedio fue 32,21+10,62 [16-74] años, 318 (54%) hombres e IMC promedio 25,25+3,75 [16,5-39,8] Kg/m2. Afirmaron presentar ronquido 27% (84/315) de los hombres y 18% (50/269) de mujeres. Refirieron pausas respiratorias durante el sueño 11 % (37/313) de los hombres y 16% (43/264) de mujeres. Reconocieron somnolencia diurna 30% (96/316) de los hombres y 31% (84/271) de las mujeres. Hubo insomnio de conciliación en 61% (194/318) de los hombres y 60% (162/269) de mujeres. Para el caso del insomnio de mantenimiento las frecuencias fueron 41% (126/307) y 46% (119/258) respectivamente. Refirieron despertarse más temprano de lo deseado 59% (189/318) de los hombres y 55% (147/266) de mujeres. Síntomas sugestivos de síndrome de piernas inquietas en 36% (111/307) de los hombres y 32% (82/255) mujeres. Refirieron síntomas relacionados a mioclonus nocturno 24% (77/315) hombres y 23% (62/268) mujeres. Según los encuestados, 33% (196) consideró que tenía algún problema para dormir. Sólo el 16 % (32/196) consultó al médico por dicha razón. Conclusiones: Los resultados de la encuesta muestran la elevada frecuencia de los síntomas asociados a diversos trastornos de sueño así como los cambios observados de acuerdo al género y la edad. La escasa importancia que los médicos y pacientes conceden al tema, justifican la implementación de intervenciones educativas en ambos casos.
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Kumar, Anita, Sanjai Kumar, Thong P. Le, Scott Southwood, John Sidney, Joe Cohen, Alessandro Sette, and Stephen L. Hoffman. "HLA-A*01-Restricted Cytotoxic T-Lymphocyte Epitope from the Plasmodium falciparum Circumsporozoite Protein." Infection and Immunity 69, no. 4 (April 1, 2001): 2766–71. http://dx.doi.org/10.1128/iai.69.4.2766-2771.2001.

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ABSTRACT Here, we report the identification of a novel CD8+cytotoxic T-lymphocyte epitope on the Plasmodium falciparumcircumsporozoite protein (3D7; amino acids 310 to 319 [EPSDKHIKEY]) that is restricted by HLA-A*01 and is recognized by human volunteers immunized with irradiated P. falciparum sporozoites. HLA-A*01 is the second most common HLA allele among Caucasians.
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Ciccarese, Chiara, Roberto Iacovelli, Emilio Bria, Giovanni Schinzari, Ernesto Rossi, Serena Astore, Maria Antonella Cannella, et al. "Efficacy of VEGFR-TKI plus immune checkpoint inhibitor (ICI) in metastatic renal cell carcinoma (mRCC) patients with favorable IMDC prognosis." Journal of Clinical Oncology 39, no. 6_suppl (February 20, 2021): 318. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.318.

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318 Background: Combinations of a PD-1/PD-L1 immune checkpoint inhibitor (ICI) with a VEGFR-TKI as front-line/treatment-naïve therapy significantly improve the outcome of metastatic renal cell carcinoma (mRCC) patients. The benefit of these combinations is well evident in IMDC intermediate- and poor-risk population, while it is unclear in the subgroup of mRCC patients with favorable prognosis. We performed a meta-analysis with the aim to evaluate whether the addition of ICIs to VEGFR-TKIs is able to improve the outcome compared to VEGFR-TKIs alone in mRCC patients with favorable IMDC prognosis. Methods: This meta-analysis searched MEDLINE/PubMed, the Cochrane Library and ASCO Meeting abstracts for phase II or III randomized clinical trials (RCTs) testing the combination of VEGFR-TKI+ICI in mRCC. Data extraction was conducted according to the PRISMA statement. The hazard ratios (HRs) for PFS and OS with the relative 95% CIs were extracted from each study. Summary HRs was calculated using random- or fixed-effects models, depending on the heterogeneity of the included studies. Results: Three RCTs were selected for the final analysis, with a total of 605 patients (306 treated with VEGFR-TKI+ICI combinations and 299 who received sunitinib in the control arms). The combination of VEGFR-TKI+ICI improved PFS compared to sunitinib, with a 30% reduction of the risk of progression (fixed-effect, HR=0.70; p = 0.003). However, VEGFR-TKI+ICI combinations did not significantly prolong OS (fixed-effect; HR = 0.94; 95% CI 0.62–1.43; p = 0.77). Conclusions: Our analysis demonstrates a PFS benefit without an OS advantage for VEGFR-TKI+ICI combinations as first-line therapy for mRCC patients with favourable prognosis according to IMDC. Longer follow-up is required to definitely confirm the best therapy for treatment-naïve mRCC patients with favorable prognosis. [Table: see text]
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WATANABE, Takashi, Hideo TANIGUCHI, Ken-ichi HIRAKAWA, and Masaharu KANEKO. "318 Cavitation Flow due to a Cock Valve." Proceedings of Conference of Tohoku Branch 2001 (2001): 101–2. http://dx.doi.org/10.1299/jsmeth.2001.101.

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Mandl, Christian W., Steven L. Allison, Heidemarie Holzmann, Tamara Meixner, and Franz X. Heinz. "Attenuation of Tick-Borne Encephalitis Virus by Structure-Based Site-Specific Mutagenesis of a Putative Flavivirus Receptor Binding Site." Journal of Virology 74, no. 20 (October 15, 2000): 9601–9. http://dx.doi.org/10.1128/jvi.74.20.9601-9609.2000.

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ABSTRACT The impact of a specific region of the envelope protein E of tick-borne encephalitis (TBE) virus on the biology of this virus was investigated by a site-directed mutagenesis approach. The four amino acid residues that were analyzed in detail (E308 to E311) are located on the upper-lateral surface of domain III according to the X-ray structure of the TBE virus protein E and are part of an area that is considered to be a potential receptor binding determinant of flaviviruses. Mutants containing single amino acid substitutions, as well as combinations of mutations, were constructed and analyzed for their virulence in mice, growth properties in cultured cells, and genetic stability. The most significant attenuation in mice was achieved by mutagenesis of threonine 310. Combining this mutation with deletion mutations in the 3′-noncoding region yielded mutants that were highly attenuated. The biological effects of mutation Thr 310 to Lys, however, could be reversed to a large degree by a mutation at a neighboring position (Lys 311 to Glu) that arose spontaneously during infection of a mouse. Mutagenesis of the other positions provided evidence for the functional importance of residue 308 (Asp) and its charge interaction with residue 311 (Lys), whereas residue 309 could be altered or even deleted without any notable consequences. Deletion of residue 309 was accompanied by a spontaneous second-site mutation (Phe to Tyr) at position 332, which in the three-dimensional structure of protein E is spatially close to residue 309. The information obtained in this study is relevant for the development of specific attenuated flavivirus strains that may serve as future live vaccines.
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Du, Benni, and Weichao Zhang. "Theoretical Insight into the Reaction Mechanism and Kinetics for the Criegee Intermediate of anti-PhCHOO with SO2." Molecules 25, no. 13 (July 3, 2020): 3041. http://dx.doi.org/10.3390/molecules25133041.

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In this study, the density functional theory (DFT) and CCSD(T) method have been performed to gain insight into the possible products and detailed reaction mechanism of the Criegee intermediate (CI) of anti-PhCHOO with SO2 for the first time. The potential energy surfaces (PESs) have been depicted at the UCCSD(T)/6-311++G(d,p)//UB3LYP/6-311++G(d,p) levels of theory with ZPE correction. Two different five-membered ring adducts, viz., endo PhCHOOS(O)O (IM1) and exo PhCHOOS(O)O (IM2) have been found in the entrance of reaction channels. Both direct and indirect reaction pathways from IM1 and IM2 have been considered for the title reaction. Our calculations show that the formation of PhCHO+SO3 (P1) via indirect reaction pathways from IM1 is predominant in all the pathways, and the production of P1 via direct dissociation pathway of IM1 and indirect reaction pathways of IM2 cannot be neglected. Moreover, PhCOOH+SO2 (P2) initiated from IM2 is identified as the minor product. According to the kinetic calculation, the total rate constant for the anti-PhCHOO+SO2 reaction is estimated to be 6.98 × 10−10 cm3·molecule−1·s−1 at 298 K.
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Hasegawa, Hiroshi, Yoshiki Sohrin, Masakazu Matsui, Noriko Takeda, and Kazumasa Ueda. "Chemical speciation of inorganic and methylarsenic(III) compounds in aqueous solutions." Applied Organometallic Chemistry 16, no. 8 (2002): 446–50. http://dx.doi.org/10.1002/aoc.318.

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Dissertations / Theses on the topic "IMI 318"

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Wang, Zhiming. "Machining of aerospace superalloys with coated (PVD and CVD) carbides and self-propelled rotary tools." Thesis, London South Bank University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321824.

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Two aerospace superalloys, Inconel 718 and IMI 318, were machined with different grades of PVD (KC730 and KC732) and CVD (KC950) coated tools in order to evaluate their performance under various cutting conditions and to further investigate the effect of the machining conditions on surface finish and surface integrity of the work materials. A self-propelled rotary tool was also developed and used for machining under the finishing conditions. Tool wear, component forces and surface roughness were recorded and analysed during the machining trials. Study of the surface integrity involved physical as well as metallographic examination and analysis of the machined surfaces. The results of the machining trials show that the multi-layer (TiN/TiCN/TiN) PVD coated KC732 tools gave the best overall performance when machining both Inconel 718 and IMI 318, especially at lower feed conditions. Flank wear, excessive chipping, flaking of tool materials close to the cutting edge or on the rake face were the dominant failure modes when machining with the PVD coated tools while flank wear and notching were dominant when cutting with the CVD coated tools. These failure modes are associated with attrition, abrasion, diffusion and plastic deformation wear mechanisms acting individually or in combination during machining. The statistical regression analysis of the tool life data shows that wear of the PVD and CVD coated tools used for machining Inconel 718 was mainly affected by cutting speeds employed while cutting speed and feed rate exhibited similar influence on tool performance when machining IMI 318 with PVD coated tools. Tool life equations for each of the three coated grades when machining both superalloys under the cutting conditions investigated were derived. Severe plastic deformation and hardening of the machined surfaces occurred after machining both materials due to a combined action of increased component forces, thus increased stresses, and high temperature. Softening of the top surface layer when machining IMI 318 can be attributed to overaging of the titanium as a result of highly localised surface heating during machining. Tearing of the machined surfaces occurred when machining IMI 318 with the PVD coated tools, particularly with KC732 tools as a result of irregular flank wear and excessive chipping of KC732 tools. The self-propelled rotary tool (SPRT) incorporating K68 straight grade carbide exhibited superior wear-resistance when machining IMI 318 due to the absence of thermally related wear mechanisms caused by reduced temperature and the use of the entire edge of a round insert during rotary cutting. The minimal subsurface alterations (such as plastic deformation and hardness) when machining Inconel 718 and IMI 318 with the SPRT can also be attributed to lower cutting temperature with rotary action.
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Orman, Robin George. "Characterisation of novel antimony (III) oxide-containing glasses." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/3184/.

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The structures of several glass systems containing the lone-pair cation Sb3+ have been studied using a range of techniques, including neutron diraction, Mössbauer spectroscopy, Raman spectroscopy, energy-dispersive X-ray (EDX) analysis, X-ray diraction and density measurements. Comparisons with some related crystals have also been used to identify structural features. An Sb2O3 glass was prepared by roller-quenching and found to be both fully amorphous and free of contaminants, using X-ray diraction and EDX analysis, respectively. A glass transition temperature, Tg, of 250(2) °C and a crystallisation temperature, Tc, of 303(2) °C were measured using dierential scanning calorimetry, whilst the density of the glass was found to be 5:27(2) g cm3. Analysis of the total correlation function T(r) from neutron diraction of the sample found two distinct peaks at 1:972(1)Å and 2:092(4) Å, with a total Sb-O coordination number of 3:24(4), indicating the presence of some [Sb3+O4] and/or [Sb5+O6] units, in addition to the main [Sb3+O3] network. Several models of the local structure are proposed, based on dierent possible amounts of Sb5+ present in the glass. An antimony oxychloride glass was prepared from crystalline Sb8O11Cl2 by splatquenching, and Mössbauer spectroscopy was used to determine that it contained no Sb5+. The thermal events in the system were characterised, with Tg = 278(2) °C and Tc = 318(2) °C; the density was found to be 5:10(2) g cm3. Neutron diraction of the crystal distinguished between two dierent structural models in the literature, whilst also indicating that the glass may consist of similar chains of [Sb3+O3] and [Sb3+O4] units. Glasses of nominal composition x Sb2O3 . (1 - x) B2O3 were studied over the range x = 0:1 to x = 0:7. Raman spectroscopy and neutron diraction indicated that the glass network consists of significant amounts of [B3O6] boroxol rings at low x that are cleaved by the introduction of [Sb3+O3] trigonal pyramids. At higher x, there is some evidence for Sb-O-Sb bonding, resulting in the persistence of the boroxol rings to x - 0:7. Two Sb-O distances were apparent in the T(r), suggesting similar models of the antimony oxide units to those for the Sb2O3 glass. Five antimony silicate glasses of nominal composition x Sb2O3 . (1 - x) SiO2 were prepared and found by Mössbauer spectroscopy to contain growing amounts of Sb5+ with increasing x, up to 9:9(5)% at x = 0:8. Density measurements suggested that the SiO2 and Sb2O3 networks mix in the glass without significantly altering each other, and this is supported by comparison of the measured neutron diraction T(r) with a weighted sum of the total correlation functions of the two system end-members. The simulation also indicated fewer high-coordination antimony oxide units ([Sb 3+O4], [Sb5+O6]) than in the Sb2O3 glass, although two distinct Sb-O distances were once again apparent in the neutron T(r). The overall conclusion is that Sb2O3 forms a glass network consisting predominantly of [Sb3+O3] trigonal pyramids with a stereochemically-active lone-pair, whilst some more highly-coordinated [Sb3+O4] and [Sb5+O6] units may also be present.
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Alexander, Heather. "Recreating Richard III: The Power of Tudor Propaganda." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/honors/338.

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Because it signified the violent transition from the Plantagenet to Tudor dynasty, the death of King Richard III at the Battle of Bosworth’s Field was a monumental event. After five centuries, his skeleton was rediscovered by an archaeological team at a site, formerly the location of the Greyfriars Priory Church. The presentation uses the forensic evidence to examine the extent to which the perceived image of Richard III is the result of Tudor propaganda.
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Joseph, Sabrina S. "Functional Analysis of the YopN/SycN/YscB/TyeA Complex of Yersinia pestis." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/312.

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A plasmid-encoded Type III Secretion System (T3SS) is employed by human pathogenic yersiniae to inject effector proteins, termed Yops, directly into host cells. The secretion of Yops is tightly regulated, and occurs only upon contact with a eukaryotic cell in vivo or in media devoid of calcium in vitro. A complex containing the secreted protein YopN, its heterodimeric chaperone SycN/YscB, and TyeA is required to prevent secretion of effector Yops until the appropriate secretion-triggering signals are encountered. The mechanism by which these proteins regulate the T3S process is unknown. A mutational analysis of YopN and TyeA was performed to identify regions and residues of these proteins that are required to regulate Yop secretion. Amino-acid residues of TyeA were identified that were specifically required for the interaction of TyeA with YopN, confirming that the YopN/TyeA interaction is essential for the regulation of Yop secretion. Furthermore, analysis of TyeA mutants identified a surface-exposed region that was critical for the regulation of Yop secretion, but not required for interaction with YopN. YopN residues critical for the regulation of secretion clustered within the N- and C-terminal regions of YopN that were required to interact with the SycN/YscB chaperone and TyeA, respectively. No residues critical for the regulation of secretion were identified in the central region of YopN, suggesting that this region acts primarily to maintain proper positioning of the functional N- and C-terminal regions of this complex. A novel role for the chaperone binding domain (CBD) of YopN in the regulation of Yop secretion was identified. This role was separate from its role in binding the SycN/YscB chaperone and targeting YopN for secretion. Finally, it was demonstrated that the SycN/YscB chaperone is dispensable for the regulation of secretion if the expression of both YopN and TyeA is increased, indicating that these chaperones have no direct role in the regulation of Yop secretion. These results indicate that the YopN secretion signal and SycN/YscB chaperone function to efficiently target the YopN/TyeA complex to the T3S apparatus, whereas the YopN CBD and C-terminal region of YopN complexed with TyeA mediate the block in Yop secretion.
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Webster, Stacey. "Development of gold(I)- and indium(III)-catalysed reactions." Thesis, Heriot-Watt University, 2016. http://hdl.handle.net/10399/3180.

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This thesis contains an introductory chapter to gold(I)- and indium(III)-catalysis, followed by five chapters outlining the research undertaken by the author during the duration of study. Chapter 1 gives an introduction to gold(I)- and indium(III)-catalysis and, in particular, focuses on the reported literature on the development of the gold(I)-catalysed reactions of allenes. Chapter 2 describes the research undertaken into the dehydrative thiolation of allenols, and the discovery of InCl3 as a superior catalyst for this reaction compared to Au(I). The use of InCl3 as a catalyst provided excellent regioselectivities of the desired 1,3-diene products in good to excellent yields. Several reactions were carried out using a gold(I) catalyst for comparison, but they consistently provided lower yields and poorer regioselectivities. Mechanistic studies outlining the differences between Au(I) and In(III) are also discussed. Chapter 3 details the developments on the dehydrative reactions of allylic alcohols to form allylic ethers, with an In(III) vs. Au(I) comparison. These investigations show that InCl3 can be used as a cheaper alternative to Au(I) for this reaction and, in some cases, outperforms Au(I). In particular, In(III) exhibited superior performance as a catalyst when substrates or nucleophiles contain pendent π bonds. Chapter 4 presents the successful development of a mild protodeboronation reaction of boronic acids under gold(I)-catalysis. Additive free conditions and the use of “green” solvents provides a mild reaction with an excellent functional group tolerance. This method can be adapted for a regioselective ipso-deuteration technique which would be useful in labelling studies. Mechanistic investigations are also discussed. Chapter 5 outlines a quick and efficient iododeboronation reaction which can be carried out in “green” solvents in under 10 mins, making this reaction potentially useful for radiolabelling studies. Chapter 6 describes the first intermolecular gold(I)-catalysed chirality transfer hydroalkoxylation reaction of 1,3-disubstituted allenes. These reactions proceed with excellent regioselectivity and a high degree of chirality transfer. Mechanistic studies are also discussed.
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Zulu, Unomsa. "The photochemistry of the azidopentaammine rhodium ( III ) complex: triplet state." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 1988. http://digitalcommons.auctr.edu/dissertations/313.

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Tarantino, Paul M. "Development of the Antibiotic Potential of a Unique Family of DNA Polymerase Inhibitors." eScholarship@UMMS, 1998. https://escholarship.umassmed.edu/gsbs_diss/311.

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The work in the Brown laboratory has two long-range objectives. Both are derived from an interest in the replication of the genome of Gram-positive eubacteria. One objective is to gain a deeper understanding of the structure and function of DNA polymerase III, the unique species of DNA polymerase which is essential for chromosome replication. The second objective, the one from which this thesis is derived, is to determine whether a selective inhibitor of this DNA polymerase can serve as a basis for producing a new generation of clinically useful Gram-positive-selective antimicrobial agents. The polymerase III-specific inhibitor prototypes investigated in this work are members of a family of simple 6-substituted uracils. The following members of this family, TMAU and EMAU, were used as platforms for the manipulation of the N3 atom (arrow), the only ring component which could be substituted without severe reduction of inhibitory activity. The N3 position was substituted with a series of alkyl groups of increasing size. The resulting structure-activity relationships at the level of the polymerase was consistent with the presence of an N3-specific subdomain within the inhibitor binding site which could accommodate a wide variety of substituents. Although specific alkyl substituents at N3 also significantly enhanced the antibacterial potency of TMAU and EMAU, the respective compounds were found to have insufficient aqueous solubility for successful application in in vivo infection. To increase aqueous solubility, the N3 atom of the EMAU platform was substituted with selected hydroxy- and methoxyalkyl groups. The latter agents retained both anti-polymerase and antibacterial activity, and, as expected, they displayed a combination of lipid and aqueous solubility favorable to efficacy in in vivo infection. Two of the agents, N3-hydroxypropyl- and N3-methoxypropyl-EMAU were examined for their ability to protect mice from lethal staphylococcal infection. Both were found to be active in this model. In sum, the results of this work demonstrated, for the first time, that: (1) the eubacterial replication-specific DNA polymerase III is a valid target for antibiotic development, and (2) the N3-substituted 6-anilinouracil platform has strong potential as a basis for novel antibiotics useful against Gram-positive bacterial infection.
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Adigun, Risikat Ajibola. "Insight into the Reactivity of Metastasis Inhibitor, Imidazolium trans-[tetrachloro (dimethyl sulfoxide)(imidazole)ruthenate(III)], with Biologically-active Thiols." PDXScholar, 2012. https://pdxscholar.library.pdx.edu/open_access_etds/378.

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Imidazolium trans-[tetrachloro (dimethyl sulfoxide)(imidazole)ruthenate(III)], NAMI-A, is an experimental metastasis inhibitor whose specific mechanism of activation and action remains to be elucidated. In the nucleophilic and reducing physiological environment; it is anticipated that the most relevant and available reductants upon introduction of NAMI-A as a therapeutic agent will be the biologically-relevant free thiols. The kinetics and mechanisms of interaction of NAMI-A with biologically-active thiols cysteamine, glutathione, cysteine and a popular chemoprotectant, 2-mercaptoethane sulfonate (MESNA) have been studied spectrophotometrically under physiologically-relevant conditions. The reactions are characterized by initial reduction of NAMI-A with simultaneous formation of dimeric thiol and subsequent ligand exchange with water to various degrees as evidenced by Electospray Ionization Mass Spectrometry. Stoichiometry of reactions shows that one molecule of NAMI-A reacted with one mole of thiol to form corresponding disulfide cystamine, dimeric MESNA, oxidized glutathione and cystine. Observed rate constants, ko, for the reaction of NAMI-A with cysteamine, MESNA, GSH and cysteine were deduced to be 6.85 + 0.3 x 10-1, 9.4 + 0.5 x 10-2 , 7.42 + 0.4 x 10-3 and 3.63 + 0.3 x 10-2 s-1 respectively. Activation parameters determined from Arrhenius plots are indicative of formation of associative intermediates prior to formation of products. A negative correlation was obtained from the Brønsted plot derived from observed rate constants and the pKa of the different thiols demonstrating significant contribution of thiolate species towards the rate. In conclusion, interactions of NAMI-A with biologically-active thiols are kinetically and thermodynamically favored and should play significant roles in in vivo metabolism of NAMI-A.
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Franco, Douglas Faza. "Síntese e caracterizações estruturais e espectroscópicas de vidros e vitrocerâmicas contendo partículas metálicas usando óxido de antimônio (III) como agente redutor." Universidade Federal de Juiz de Fora, 2015. https://repositorio.ufjf.br/jspui/handle/ufjf/312.

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O presente trabalho trata da preparação de vidros baseados em polifosfatos de sódio (NaPO3)n contendo óxidos de antimônio (III) e cobre (II), onde a presença do agente redutor α-Sb2O3 foi responsável pelos processos de oxi-redução: Cu2+→ Cu+→Cu0 durante a síntese dos vidros a 1000°C. Os resultados de medidas de absorção de Raios X próxima a borda K do Cu (XANES) e de espectroscopia Eletrônica forneceram informações valiosas sobre a existência de partículas metálicas nos vidros com dimensões nanométricas. Este resultado mostra a possibilidade de se obter nanopartículas metálicas de Cu0 durante a etapa de fusão dos vidros sem a necessidade de tratamentos térmicos dos materiais em temperaturas próximas a transição vítrea. A síntese de diferentes fases cristalinas do óxido de antimônio (III): α-Sb2O3, α-Sb2O4, β-Sb2O4 e β-Sb2O3, por meio de diferentes tratamentos isotérmicos possibilitou o estudo via espectroscopia Raman e Difração de Raios X por policristais destes compostos. O diagrama de composição ternário para os vidros (0,9-x)NaPO3-xSb2O3-0,1CuO mostra as diferentes regiões de domínio vítreo de formação de vidros estáveis. O estudo espectroscópico dos vidros (0,9-x)NaPO3-xSb2O3-0,1CuO contendo nanopartículas metálicas de Cu0 dopados com 0,5 mol% de Er2O3 foi realizado via espectroscopia de Fluorescência usando diferentes radiações excitantes: 532, 633 e 785 nm. O mapeamento Raman dos vidros mostrou a intensificação da fluorescência dos íons Er3+, tanto pelo efeito da mudança do ambiente químico ao redor do íon Er3+ (cristalização) quanto pela transferência de energia dos plasmons de superfície excitados para os níveis de energia do íon terra-rara (SEF – Surface-Enhanced Fluorescence). Além disso, vidros contendo nanopartículas metálicas de Cu0 apresentaram resultados satisfatórios quando a possibilidade de utilização como substratos SERS (Surface-Enhanced Resonance Spectroscopy), sendo observada a intensificação do sinal Raman dos modos vibracionais da o-fenilenodiamina usando o vidro x = 0,6 como substrato.
This Thesis deals with the preparation of glasses based on sodium polyphosphate, containing antimony (III) and copper (II) oxides. The presence of α-Sb2O3 reducing agent was responsible for redox processes: Cu 2+→ Cu+→ Cu0 during synthesis of the glasses at 1000°C. The results of X-ray absorption measurements near the K edge of Cu (XANES) and electronic spectroscopy provided valuable information on the presence of metallic particles in glasses with nanometric dimensions. This result shows the possibility of obtaining metallic Cu nanoparticles during the melting step of glass preparation, without the need for posterior treatments. The synthesis of the different crystal phases of antimony (III) oxide, i.e., α-Sb2O3, α-Sb2O4, β-Sb2O4 and β-Sb2O3, through different isothermal treatments enabled the study through Raman spectroscopy and X-ray Diffraction. The ternary composition diagram for glass NaPO3-Sb2O3-CuO shows the different regions of vitreous domain. The spectroscopic study of glasses (0.9-x)NaPO3- xSb2O3-0,1CuO, containing Cu nanoparticles doped with 0.5 mol% of Er2O3 was realized by fluorescence spectroscopy using different exciting radiation: 532, 633 and 785 nm. The Raman mapping of these glasses showed the intensification of fluorescence of Er3+ ions, both the effect of changing the chemical environment around the Er3+ ion (crystallization) as the energy transfer from the excited surface plasmons for energy rare-earth ion levels (SEF - Surface-Enhanced Fluorescence). Additionally, glasses containing Cu nanoparticles showed satisfactory results of use as SERS substrates (Surface-Enhanced Resonance Spectroscopy), with the observed enhancement of the Raman signal of the vibrational modes of using phenylenediamine and the glass with x = 0.6 as substrate.
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Bobadilla, Labán Fressia Naymé, and Pinto Azalia Ashley Durand. "Conocimiento sobre los derechos del paciente en los usuarios del servicio de cirugía del Hospital Suárez Angamos III-EsSlud." Bachelor's thesis, Universidad Ricardo Palma, 2014. http://cybertesis.urp.edu.pe/handle/urp/315.

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Introducción: el tema de los derechos humanos es uno de los que más publicidad ha tenido estos últimos tiempos, los derechos de los pacientes se encuentran dentro de éstos; los pacientes, que son los directos beneficiarios luchan actualmente con una sociedad globalizada, llena de tecnología y que brinda toda clase de información, muchas veces no entendida; lo cual ocasiona desconocimiento en cuanto a sus derechos y por ende el desinterés de exigirlos.Objetivo: determinar el nivel de conocimiento sobre los derechos de los pacientes en los usuarios del servicio de cirugía del Hospital Suárez Angamos. Método: el presente trabajo es de tipo cuantitativo, diseño descriptivo, de corte transversal; con una muestra probabilística representativa de 234 acudieron al servicio de cirugía en su etapa preoperatoria. Los datos se obtuvieron a través de un instrumento elaborado por las investigadoras que recopiló información sobre el conocimiento que tienen los usuarios acerca de sus derechos: autonomía y a ser informado; la recolección se realizó durante el mes de Enero 2014. Los datos fueron procesados y analizados por la estadística descriptiva en el estadístico SPS v.19. Resultados: el conocimiento medio prevaleció en las tres dimensiones medidas, aspectos generales 70,2%; derecho a ser informado 61,2% y derecho de autonomía con 68,5%.
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Books on the topic "IMI 318"

1

Brennecke, Hanns Christof, Uta Heil, Annette Stockhausen, and Angelika Wintjes, eds. Band III/Teil 1: Urkunden zur Geschichte des Arianischen Streites 318-328, Lfg 3, Bis zur Ekthesis Makrostichos. Berlin, Boston: DE GRUYTER, 2007. http://dx.doi.org/10.1515/9783110927351.

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Godement, Roger. Analysis III. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16053-5.

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Grattarola, Pio. I cesariani dalle idi di marzo alla costituzione del secondo triumvirato. Torino: Tirrenia stampatori, 1990.

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Sasiadek, Jerzy, ed. Aerospace Robotics III. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-94517-0.

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Böttcher, Björn, René Schilling, and Jian Wang. Lévy Matters III. Cham: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-02684-8.

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Prokop, Aleš, and Volkmar Weissig, eds. Intracellular Delivery III. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-43525-1.

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Watanabe, Norihiro, Guido Blöcher, Mauro Cacace, Sebastian Held, and Thomas Kohl. Geoenergy Modeling III. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-46581-4.

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Kapandji, I. A. Bewegingsleer: deel III. Houten: Bohn Stafleu van Loghum, 2009. http://dx.doi.org/10.1007/978-90-313-7299-7.

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Kohnstamm, Rita. Kleine ontwikkelingspsychologie III. Houten: Bohn Stafleu van Loghum, 2009. http://dx.doi.org/10.1007/978-90-313-7589-9.

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A, Kincaid C. Successors of Alexander the Great: Ptolemy I, Pyrrhus of Epirus, Hiero of Syracuse, Antiochus III. Chicago, IL: Ares, 1985.

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Book chapters on the topic "IMI 318"

1

Wortmann, Thomas. "III.3.8 Rezeption und Publikum." In Grundthemen der Literaturwissenschaft: Drama, edited by Andreas Englhart and Franziska Schößler, 497–511. Berlin, Boston: De Gruyter, 2018. http://dx.doi.org/10.1515/9783110379594-026.

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Palewski, T., and W. Suski. "Fig. 317 - 351." In Pnictides and Chalcogenides II (Ternary Lanthanide Pnictides). Part a: 1:1:1 and 1:1:2 Type Compounds, 329–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/10713493_22.

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Palewski, T., and W. Suski. "Fig. 31i - 46i." In Pnictides and Chalcogenides II (Ternary Lanthanide Pnictides). Part a: 1:1:1 and 1:1:2 Type Compounds, 26–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/10713493_4.

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Palewski, T., and W. Suski. "Fig. 294 - 316, Table 12 - 13." In Pnictides and Chalcogenides II (Ternary Lanthanide Pnictides). Part a: 1:1:1 and 1:1:2 Type Compounds, 306–28. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/10713493_21.

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Brandstätter, Ursula. "Hans Mersmanns Analyse der »Klaviersonate KV 311« von Wolfgang Amadeus Mozart." In Musik im Spiegel der Sprache, 74–92. Stuttgart: J.B. Metzler, 1990. http://dx.doi.org/10.1007/978-3-476-04460-0_5.

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Gentili, Giuliano, and Mario Di Napoli. "Digit III; Digit III – Wrist." In The Median Nerve, 55–60. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-10476-8_9.

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Gerke, R. David, and William A. Jesser. "Fracture in Helium-Irradiated Type 316 Stainless Steel Microtensile Specimens." In Effects of Radiation on Materials: 12th International Symposium Volume II, 605–18. 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959: ASTM International, 1985. http://dx.doi.org/10.1520/stp87019850005.

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Gentili, Giuliano, and Mario Di Napoli. "Digit III – Palm, Digit III – Wrist." In The Median Nerve, 283–87. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-10476-8_40.

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Bakker, Aert. "Elleboog III." In Functioneel tapen en bandageren, 22. Houten: Bohn Stafleu van Loghum, 1996. http://dx.doi.org/10.1007/978-90-313-9663-4_10.

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Komaba, Shigeru. "Myosin III." In Encyclopedia of Signaling Molecules, 3310–14. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_541.

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Conference papers on the topic "IMI 318"

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Cooke, Adam, Peter Childs, and Christopher Long. "Investigation Into the Effect of Uncertainty in Thermal Properties on Turbomachinery Disc Heat Transfer Using Both a Monte Carlo Simulation Technique and a Taylor Series Uncertainty Propagation Method." In ASME Turbo Expo 2007: Power for Land, Sea, and Air. ASMEDC, 2007. http://dx.doi.org/10.1115/gt2007-27573.

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The effect of uncertainties in the thermal properties of components and surrounding fluids is often ignored in the field of experimental turbomachinery heat transfer. The work reported here uses two different methods of uncertainty analysis to help quantify these effects: 1) a stochastic Monte Carlo simulation and 2) a Taylor series uncertainty propagation. These two methods were used on a steady state free disc test case having a turbulent flow regime. The disc modelled was made from IMI 318 titanium and had an inner and outer radius of 0.115 m and 0.22 m respectively, representative of engine and test rig geometry. The disc thickness was 0.016 m. Convective boundary conditions were derived from the relevant equation for local Nusselt number. The applied boundary conditions resulted in local heat transfer coefficients in the range of approximately 120 W/m2 K to 170 W/m2 K. Uncertainties for these heat transfer coefficients were a near identical match between the two different uncertainty methods and were found to be ± 0.66%. Calculated heat flux values fell within the range of approximately 1500 W/m2 and 5200 W/m2. The Monte Carlo uncertainty method returned uncertainty values varying from ± 1.17% to ± 0.47% from the inner and outer radii respectively. An extended Taylor series of uncertainty propagation returned uncertainties varying from ± 1.82% to ± 0.96%, from the inner and outer radius respectively and increased and decreased a number of times in between. These differences are due to assumptions and simplifications which need to be made when using the Taylor series method and shows that a Monte Carlo simulation analysis offers a better way of quantifying the uncertainties associated with disc to air heat transfer as it is more realistic. Studying the magnitudes of uncertainty allows the analyst to understand the impact that uncertainties in thermal properties can have on calculated values of disc to air heat fluxes and heat transfer coefficients.
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Notholt, Justus, H. Schuett, and A. Keens. "Measurements of stratospheric OH at 308 nm with the sun as light source using a Fourier transform spectrometer." In Environmental Sensing III, edited by Klaus Schaefer. SPIE, 1997. http://dx.doi.org/10.1117/12.274721.

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Dizdarević, Denis, Iztok Podbregar, and Miha Marič. "Pomembnost prenosa vojaških veščin na civilno prebivalstvo." In Organizations at Innovation and Digital Transformation Roundabout: Conference Proceedings. University of Maribor Press, 2020. http://dx.doi.org/10.18690/978-961-286-388-3.8.

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Vojska in njeno usposabljanje, kot temelj suverene države in ključni del nacionalno varnostnega sistema, ima pomembno vlogo pri pripravljenosti na izredne razmere ter varnosti države. Slovenija se sooča s pomanjkanjem stalne in rezervne vojaške sestave. Na podlagi kritičnega pregleda sekundarnih virov in kompilacije smo opisali zakaj je pomembno vojaško usposabljanje ter zakaj je pomemben prenos teh veščin in znanj na civilno prebivalstvo. Podali smo stališča in argumente. Ugotovili smo, da so vojaška znanja in veščine ključne v delovanju izrednih razmer, kot so bile nesreče Černobil 1986, Fukushima Dai-ichi 2011 in avstralski požari 2019-2020; ter, da obstaja več priporočil in pozivov za usposabljanje državljanov. Potrebno je raziskati, katera vojaška znanja in veščine naj prebivalstvo pridobi, ter postaviti model prenosa. Te veščine in znanja so pomembna tako v naravnih in tehnoloških nesrečah, kot v obrambi pred morebitnim sovražnikom. Bolje biti pripravljen v miru, kot nepripravljen v vojni ali izrednih razmerah.
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Устинова, О. Ю., Е. М. Власова, Ю. А. Ивашова, and А. Е. Носов. "Features of vegetative disorders in working hours with night shifts." In III International Scientific Forum "Health And Safety At The Workplace". Polikraft, 2019. http://dx.doi.org/10.31089/978-985-7153-76-3-2019-1-3-315-318.

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Thurgood, V., Steven Sargent, Ray Russell, V. Thurgood, Steven Sargent, and Ray Russell. "Spatial Infrared Imaging Telescope (SPIRIT III) performance assessment and certification methodologies." In 35th Aerospace Sciences Meeting and Exhibit. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1997. http://dx.doi.org/10.2514/6.1997-311.

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Ahmed, Faisal, Muhammad Furqan, Klaus Aufinger, and Andreas Stelzer. "A SiGe-based wideband 220–310-GHz subharmonic receiver front-end for high resolution radar applications." In 2017 IEEE/MTT-S International Microwave Symposium - IMS 2017. IEEE, 2017. http://dx.doi.org/10.1109/mwsym.2017.8058754.

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Saad, Paul, Rui Hou, Richard Hellberg, and Bo Berglund. "An 80W Power Amplifier with 50% Efficiency at 8dB Power Back-off over 2.6-3.8 GHz." In 2019 IEEE/MTT-S International Microwave Symposium - IMS 2019. IEEE, 2019. http://dx.doi.org/10.1109/mwsym.2019.8701113.

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Gaspar, M. C., A. Ramalho, and A. Cavaleiro. "Effect of the Substrate on the Fretting Wear of Sputtered W-Si-N Coatings Against Steel." In World Tribology Congress III. ASMEDC, 2005. http://dx.doi.org/10.1115/wtc2005-63709.

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Fretting tests of sputtered W-Si-N amorphous coatings were performed on both cemented tungsten carbide with 6wt.% of Co and AISI 310 steel substrates against spherical AISI 52100 steel counterbodies. The normal load and the amplitude of relative displacement were varied. The evolution of the tangential force during the test was recorded. At the end of each test, the volume and the surface morphology of the wear scars were measured and analyzed. The relationship between the dissipated frictional energy and the wear volume was calculated. The results allowed plotting fretting maps identifying the occurrence of different fretting regimes.
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Устинова, О. Ю., Н. В. Зайцева, Е. М. Власова, and А. Е. Носов. "Production factors as predictors of structural and functional vascular disorders in workers engaged in underground mining of polymetallic ore." In III International Scientific Forum "Health And Safety At The Workplace". Polikraft, 2019. http://dx.doi.org/10.31089/978-985-7153-76-3-2019-1-3-310-315.

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Tuszynski, Waldemar, Witold Piekoszewski, and Marian Szczerek. "Scuffing Initiation, Scuffing Propagation and Pitting of a Four-Ball Tribosystem Lubricated With Mineral and Synthetic Oils." In World Tribology Congress III. ASMEDC, 2005. http://dx.doi.org/10.1115/wtc2005-63445.

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The research aimed at finding an effect of various base oils on the scuffing initiation, scuffing propagation and pitting. The following base oils were tested: mineral oil, synthetic hydrocarbon oil (polyalphaolefins), synthetic non-hydrocarbon oils (polyol ester, polyglycol) and highly refined mineral one known as a white oil. The tests were performed in two different four-ball testers. One was used to investigate scuffing at pure sliding friction. The second instrument was employed to test pitting at rolling movement. To avoid an effect of the oil viscosity, base oils having similar viscosities ν100 (3,8 – 5,5 mm2 s−1) were compared. In this group the highest load causing the scuffing initiation is given by the polyglycol, and the lowest one — by polyalphaolefins and white oil. The scuffing propagation is similar for all the oils. The best resistance to pitting is given by the mineral oil, and the worst — by the white oil.
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Reports on the topic "IMI 318"

1

Carlstrom, R. F. Safety evaluation for packaging transport of LSA-II liquids in MC-312 cargo tanks. Office of Scientific and Technical Information (OSTI), September 1996. http://dx.doi.org/10.2172/670054.

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Bornemann, Tobias, Adrian Schipp, and Caren Sureth-Sloane. Umfrage zur Steuerkomplexität in deutschen Finanzverwaltungen. TRR 266 Accounting for Transparency, 2020. http://dx.doi.org/10.52569/ilcp9945.

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Dieser Bericht stellt deskriptive Ergebnisse der Befragung von 317 MitarbeiterInnen im Bundeszentralamt für Steuern und in Finanzverwaltungen ausgewählter Bundesländer zur wahrgenommenen Steuerkomplexität in Deutschland 2018/2019 vor.
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Environmental Stewardship Group (ENV-ES). 2009 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313. Office of Scientific and Technical Information (OSTI), November 2010. http://dx.doi.org/10.2172/991238.

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M. Stockton. 2004 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313. Office of Scientific and Technical Information (OSTI), January 2006. http://dx.doi.org/10.2172/878899.

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Stockton, M. 2002 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313. Office of Scientific and Technical Information (OSTI), November 2003. http://dx.doi.org/10.2172/833495.

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M. Stockton. 2003 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313. Office of Scientific and Technical Information (OSTI), December 2004. http://dx.doi.org/10.2172/835946.

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Heather McBride. 1997 Toxic Chemical Release Inventory Report for the Emergency Planning and Community Right-to-Know Act of 1986, Title III, Section 313. Office of Scientific and Technical Information (OSTI), July 1997. http://dx.doi.org/10.2172/9413.

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Saul, Victor D. Performance Oriented Packaging Testing of Container, Shipping and Storage, CNU-316/E for Packing Group II Solid Hazardous Materials. Fort Belvoir, VA: Defense Technical Information Center, August 1992. http://dx.doi.org/10.21236/ada254151.

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Christian, Keuschnigg, Gerald Gogola, Julian Johs, Mara Kritzinger, and Sascha Sardadvar. Wirkung von Forschungsausgaben. WPZ Research GmbH, May 2021. http://dx.doi.org/10.22163/fteval.2021.511.

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Wie groß sind die Wirkungen der Ausgaben für Forschung und Entwicklung (F&E)? Mit F&E bauen die Unternehmen ihre Wettbewerbsfähigkeit aus und sichern die künftigen Gewinne. Die Forschungsförderung regt die F&E‐Investitionen an und verhilft innovativen Unternehmen zu mehr Wachstum. Mit ökonometrischen Matching‐Methoden vergleichen wir die Entwicklung von Unternehmen, die durch die FFG gefördert wurden, relativ zu nicht‐geförderten, aber sonst ganz ähnlichen Unternehmen. Unternehmen, die eine FFG‐Förderung erhalten, konnten im Zeitraum 2016‐2019 ihre Beschäftigung um 7,1 % steigern, andere vergleichbare Unternehmen nur um 0,4 %. Das Umsatzwachstum beträgt 10,8 % statt 2,5 %. Mit einem detaillierten Innovationsmodell der österreichischen Wirtschaft berechnen wir die makroökonomischen Effekte von F&E‐Ausgaben. In einem Wachstumsszenario nach dem Muster der letzten zehn Jahre lassen sich etwa 28 % des Wachstums ursächlich auf die Wirkungen des Innovationssystems zurückführen. Dieser Effekt wird mit F&E‐Ausgaben von nur 3,18 % des BIPs erzielt. Eine Erhöhung der öffentlichen F&E‐Ausgaben um 1 Euro könnte langfristig das BIP um bis zu 6 Euro erhöhen. Allerdings haben F&E‐Ausgaben lange Vorlaufzeiten, so dass die positiven Wirkungen nur allmählich eintreten. Studie im Auftrag des Bundesministeriums für Digitalisierung und Wirtschaftsstandort.
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Zhang, Min. Technical Support to SBIR Phase II Project: Improved Conversion of Cellulose Waste to Ethanol Using a Dual Bioreactor System: Cooperative Research and Development Final Report, CRADA Number CRD-08-310. Office of Scientific and Technical Information (OSTI), April 2013. http://dx.doi.org/10.2172/1076643.

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