To see the other types of publications on this topic, follow the link: IMC.
Journal articles on the topic 'IMC'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'IMC.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Lima Junior, Julião Soares de Souza, Larissa Costa de Souza Lima, Thais Gomes Oliveira Laia, and Alessandra Fagioli Silva. "ANÁLISE DE AGRUPAMENTO DO IMC E DO IAC E DA RELAÇÃO IAC/IMC EM INDIVÍDUOS COM IDADE ENTRE 6 A 15 ANOS." Revista Univap 22, no. 40 (November 22, 2016): 153. http://dx.doi.org/10.18066/revistaunivap.v22i40.1501.
Full textAbstract:
Conhecer as relações entre dados antropométricos e o estado nutricional das pessoas ajuda no entendimento das tendências em uma população. Este trabalho teve o objetivo de determinar em 62 jovens com idade entre 6 a 15 anos o IMC, o IAC e a relação entre IAC/IMC e utilizar método para agrupamento dos indivíduos. Os dados foram analisados por estatística descritiva e o método de agrupamento Joining. O IMC, o IAC e a Relação IAC/IMC, apresentaram os valores médios de 18,88; 27,62 e 1,51, respectivamente. Os grupos 1 e 2 apresentaram médias maiores que a média geral dos dados para o IMC. Os grupos 2, 3 e 4 apresentaram maiores valores médios que a média geral dos dados para o IAC. Os grupos 3 e 4 com média maior que a media geral para a relação IAC/IMC. Maiores relações de IAC/IMC ocorrem para indivíduos que apresentam menores valores de IMC e os maiores de IAC. O IMC aumenta com a idade e o IAC diminui à medida que a idade aumenta.
2
Mollinedo-Cardalda, Irimia, Karina Pereira, Adriana López-Rodríguez, and José María Cancela-Carral. "Relación entre índices antropométricos y la obesidad en personas mayores de 60 años. Estudios Europeo IN COMMON SPORT." Revista Andaluza de Medicina del Deporte 14, no. 2 (August 5, 2020): 87–92. http://dx.doi.org/10.33155/j.ramd.2020.08.001.
Full textAbstract:
Objetivo: Comprobar si el índice de masa corporal (IMC), el índice cintura-cadera (ICC), circunferencia de cintura (CCi), circunferencia de cadera (CCa) y porcentaje de grasa corporal se correlacionan entre sí en personas mayores de 60 años.
Método: Se realizó un estudio descriptivo correlacional en 1055 personas mayores de 60 años de diferentes países europeos pertenecientes al proyecto europeo IN COMMON SPORTS. Se realizó una valoración inicial de las variables antropométricas.
Resultados: Correlación significativa del IMC con el porcentaje de grasa corporal, CCi y CCa pero no con el ICC. El ICC presenta correlaciones proporcionales significativas con el CCi, e inversamente proporcionales con el CCa. El género masculino muestra una correlación significativa entre el ICC y IMC, pero no con el porcentaje de grasa corporal. El IMC promedio muestra una tendencia general alta para ambos géneros. Mujeres mayor porcentaje de grasa.
Conclusión: El IMC se correlaciona con ICC, CCa y CCi pero dependiendo del género. Los hombres mostraron correlaciones significativas entre IMC e ICC, pero en las mujeres no se encuentran correlaciones de estas medidas.
3
Reis, Diony Alves, Claúdia Liane Rodrigues de Lima, and Adilson Luís Bamberg. "Qualidade física e frações da matéria orgânica de um Planossolo sob sistema plantio direto." Pesquisa Agropecuária Brasileira 51, no. 9 (September 2016): 1623–32. http://dx.doi.org/10.1590/s0100-204x2016000900062.
Full textAbstract:
Resumo O objetivo deste trabalho foi avaliar a qualidade física e as frações da matéria orgânica de um Planossolo sob sistema plantio direto (SPD), com diferentes tempos de implantação, no Sul do Brasil. Amostras de solo foram coletadas nas camadas de 0,00-0,03, 0,03-0,06, 0,06-0,10 e 0,10-0,20 m, tendo-se determinado: a porosidade total (Pt); a macroporosidade (Ma); a microporosidade (Mi); a resistência do solo à penetração (Rp); a densidade (Ds); os macro e microagregados; o diâmetro médio ponderado dos agregados (DMP); o carbono orgânico total (COT); o carbono das frações leve livre (FLL), leve oclusa (FLO) e pesada (FP); os estoques de carbono (EstC), os índices de labilidade (ILC), de estoque (IEC) e de manejo do carbono (IMC). O tempo de implantação SPD aumentou a Pt, a Ma, os EstC, e diminuiu a Mi, a Rp e a Ds. O SPD promove os atributos DMP, ILC, IEC e IMC a partir do quinto ano de implantação, e, portanto, melhora a qualidade física do solo.
4
Lu, Wei, and Ming Chun Wang. "ILC-Based Internal Model Control of Superheater Steam Temperature." Advanced Materials Research 732-733 (August 2013): 864–69. http://dx.doi.org/10.4028/www.scientific.net/amr.732-733.864.
Full textAbstract:
This paper proposes a novel Internal Model Control (IMC) method for the control of superheater steam temperature. The IMC is known for good robustness including handling of systems with time delays. While Iterative Learning Control (ILC) is a strategy for dealing with periodic disturbances. By using a combination of IMC and ILC, their individual advantages are used to increase the robustness against modeling uncertainties and handling time as well as decreasing the influence of the periodic disturbances affecting the superheater steam. Some simulation examples are shown to illustrate performance improvements that can be achieved by the new method over the conventional IMC and PID methods. Key Words: Superheater Steam Temperature; Internal Model Control; Iterative Learning Control
5
Vargas Parga, Luis Alejandro. "IMC-ICC, de los aprendices de programas técnicos y tecnólogos del SENA regional Tolima Centro de Comercio y Servicios." Vía Innova 1, no. 1 (December 15, 2014): 31. http://dx.doi.org/10.23850/2422068x.366.
Full textAbstract:
El objetivo de este trabajo es conocer los índices de IMC e ICC de los aprendices del Centro de Comercio y Servicios. Este trabajo tuvo un enfoque cuantitativo descriptivo y correlacional, respecto al IMC; como medida para establecer la relación entre peso y altura, y el ICC para conocer el riesgo cardiovascular a partir de la relación cintura/cadera.
6
Carvalho, Ferdinando Oliveira, Gabriel Gustavo Bergmann, Crisieli Maria Tomeleri, Layane Costa Saraiva, Marcos Vinicius Oliveira Carneiro, Anastácio Neco de Souza Filho, Thaynã Alves Bezerra, and Orlando Laitano Lionello Neto. "Concordância entre o índice de adiposidade corporal e percentual de gordura de adultos sedentários de Londrina - PR." Ciência em Movimento 22, no. 43 (August 10, 2020): 53. http://dx.doi.org/10.15602/1983-9480/cm.v22n43p53-61.
Full textAbstract:
O estudo objetivou verificar a concordância do percentual de gordura com o índice de adiposidade corporal (IAC) comparando com os diferentes indicadores antropométricos, e estabelecer pontos de corte para obesidade baseado no IAC de um grupo de brasileiros estratificados por sexo e faixa etária. Participaram do estudo 1.147 adultos sedentários, sendo 451 homens (27,6 ± 10,4 anos) e 696 mulheres (27,6 ± 10,4 anos). Foram analisados o percentual de gordura corporal (%G) e os indicadores antropométricos massa corporal total, índice de massa corporal (IMC), circunferência da cintura (CC) e do quadril (CQ). Os dados foram processados no SPSS versão 13.0 e Statatm versão 9.1. Para ambos os sexos e em todas as faixas etárias foi observado maior correlação do %G com o IMC e CC e correlação significativa do %G com todos os índices, sendo maior e positiva para o sexo feminino versus (vs) o masculino: IMC (0,64 vs 0,58); RCQ (0,38 vs 0,34); CC (0,65 vs 0,54); IAC (0,46 vs 0,40). Conclui-se que existem correlações significativas entre o %G aferido por dobras cutâneas e indicadores antropométricos CC, IMC, IAC e RCQ, e foi estabelecido pontos de corte para a adiposidade por meio do novo IAC e dos outros indicadores antropométricos para ambos os sexos.
7
Freire, Simone Cardoso, and Mauro Fisberg. "Adaptação da Escala de Silhuetas Brasileiras para uso digital." Jornal Brasileiro de Psiquiatria 66, no. 4 (October 2017): 211–15. http://dx.doi.org/10.1590/0047-2085000000173.
Full textAbstract:
RESUMO Objetivo Adaptar a escala de silhuetas originais em cartões de papel e validar para uso digital. Métodos Participaram dessa pesquisa 88 jovens, os quais foram avaliados quanto ao índice de massa corporal (IMC) e questões sobre a imagem corporal com as escalas de silhuetas de papel e digital em relação ao corpo atual (IMC-A) e o corpo desejado (IMC-D). O processo de validação da escala digital se dá pela comparação entre o IMC com o IMC-A. Resultados Os resultados foram satisfatórios (0,70) para o grupo quando avaliado em conjunto e para o sexo masculino. No entanto, para o sexo feminino obtivemos um valor relativamente baixo, na concordância de Lin (0,64), mas com valores de ICC (0,89) e correlação de Spearman (0,85) aceitáveis. Conclusão As imagens no computador podem ser utilizadas para a avaliação da imagem corporal de jovens. Porém, é mais seguro realizar associações com questões referentes à prática de atividade física e do comportamento alimentar que, em conjunto, possam auxiliar na avaliação da insatisfação corporal.
8
Alonso-Miguel, Daniel, Guillermo Valdivia, Diego Guerrera, Maria Dolores Perez-Alenza, Stanislav Pantelyushin, Angela Alonso-Diez, Veronique Beiss, et al. "Neoadjuvant in situ vaccination with cowpea mosaic virus as a novel therapy against canine inflammatory mammary cancer." Journal for ImmunoTherapy of Cancer 10, no. 3 (March 2022): e004044. http://dx.doi.org/10.1136/jitc-2021-004044.
Full textAbstract:
BackgroundInflammatory mammary cancer (IMC), the counterpart of human inflammatory breast cancer (IBC), is the deadliest form of canine mammary tumors. IMC patients lack specific therapy and have poor outcomes. This proof-of-principle preclinical study evaluated the efficacy, safety, and effect on survival of neoadjuvant intratumoral (in situ) empty cowpea mosaic virus (eCPMV) immunotherapy in companion dogs diagnosed with IMC.MethodsTen IMC-bearing dogs were enrolled in the study. Five dogs received medical therapy, and five received weekly neoadjuvant in situ eCPMV immunotherapy (0.2–0.4 mg per injection) and medical therapy after the second eCPMV injection. Efficacy was evaluated by reduction of tumor growth; safety by hematological and biochemistry changes in blood and plasma; and patient outcome by survival analysis. eCPMV-induced immune changes in blood cells were analyzed by flow cytometry; changes in the tumor microenvironment were evaluated by CD3 (T lymphocytes), CD20 (B lymphocytes), FoxP3 (Treg lymphocytes), myeloperoxidase (MPO; neutrophils), Ki-67 (proliferation index, PI; tumor cell proliferation), and Cleaved Caspase-3 (CC-3; apoptosis) immunohistochemistry.ResultsTwo neoadjuvant in situ eCPMV injections resulted in tumor shrinkage in all patients by day 14 without systemic adverse events. Although surgery for IMC is generally not an option, reduction in tumor size allowed surgery in two IMC patients. In peripheral blood, in situ eCPMV immunotherapy was associated with a significant decrease of Treg+/CD8+ ratio and changes in CD8+Granzyme B+ T cells, which behave as a lagging predictive biomarker. In the TME, higher neutrophilic infiltration and MPO expression, lower tumor Ki-67 PI, increase in CD3+ lymphocytes, decrease in FoxP3+/CD3+ ratio (p<0.04 for all comparisons), and no changes in CC-3+ immunostainings were observed in post-treatment tumor tissues when compared with pretreatment tumor samples. eCPMV-treated IMC patients had a statistically significant (p=0.033) improved overall survival than patients treated with medical therapy.ConclusionsNeoadjuvant in situ eCPMV immunotherapy demonstrated anti-tumor efficacy and improved survival in IMC patients without systemic adverse effects. eCPMV-induced changes in immune cells point to neutrophils as a driver of immune response. Neoadjuvant in situ eCPMV immunotherapy could be a groundbreaking immunotherapy for canine IMC and a potential future immunotherapy for human IBC patients.
9
Prayitno, Sunarto. "Komunikasi Pemasaran Global Terpadu: Tantangan di Era Digital." CoverAge: Journal of Strategic Communication 12, no. 1 (September 16, 2021): 27–39. http://dx.doi.org/10.35814/coverage.v12i1.2152.
Full textAbstract:
The discovery of computers and specifically the internet, led to fundamental changes in concept, strategy, tactic, and implementation of business, marketing, and marketing communications, which shifted from conventional to modern markets in the digital age. Integrated Marketing Communications (IMC) is a concept derived from the research made by practitioners and academics in anticipating the expiry of old strategies that are no longer reliable. In turn, IMC became a new paradigm to be used as a basic reference in facing challenges in the global market. The application of IMC concepts and strategies to the global market is known as Integrated Global Marketing Communications (IGMC) planning. Changes that occur in consumer behavior, message development patterns, the proliferation of media, especially digital media, and the integration of marketing communication elements are the basis of the IGMC strategic development plan. The implementation of the IGMC program can be expected to be a road map to achieve organizational and corporate success in the digital age. This paper synthesized the viewpoints of different experts and provides the author’s analysis, interpretation, and theorizing.
Keywords: integrated global marketing communications, global consumer, global message development, global media penetration, and IGMC planning patterns.
10
Caceres, Sara, Laura Peña, Gema Silvan, Maria J. Illera, Wendy A. Woodward, James M. Reuben, and Juan C. Illera. "Steroid Tumor Environment in Male and Female Mice Model of Canine and Human Inflammatory Breast Cancer." BioMed Research International 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/8909878.
Full textAbstract:
Canine inflammatory mammary cancer (IMC) shares clinical and histopathological characteristics with human inflammatory breast cancer (IBC) and has been proposed as a good model for studying the human disease. The aim of this study was to evaluate the capacity of female and male mice to reproduce IMC and IBC tumors and identify the hormonal tumor environment. To perform the study sixty 6–8-week-old male and female mice were inoculated subcutaneously with a suspension of 106IPC-366 and SUM149 cells. Tumors and serum were collected and used for hormonal analysis. Results revealed that IPC-366 reproduced tumors in 90% of males inoculated after 2 weeks compared with 100% of females that reproduced tumor at the same time. SUM149 reproduced tumors in 40% of males instead of 80% of females that reproduced tumors after 4 weeks. Both cell lines produce distant metastasis in lungs being higher than the metastatic rates in females. EIA analysis revealed that male tumors had higher T and SO4E1 concentrations compared to female tumors. Serum steroid levels were lower than those found in tumors. In conclusion, IBC and IMC male mouse model is useful as a tool for IBC research and those circulating estrogens and intratumoral hormonal levels are crucial in the development and progression of tumors.
11
Mussi, Ricardo Franklin de Freitas, and Edio Luiz Petróski. "Indicadores de obesidade: capacidade preditiva para síndrome metabólica em adultos quilombolas." Ciência & Saúde Coletiva 24, no. 7 (July 2019): 2471–80. http://dx.doi.org/10.1590/1413-81232018247.19032017.
Full textAbstract:
Resumo O objetivo deste estudo foi avaliar a capacidade preditiva da síndrome metabólica (SM) por diferentes indicadores de obesidade (IO) em adultos quilombolas. Estudo transversal com amostra representativa de 850 adultos (18 à 92 anos de idade) quilombolas residentes na microrregião geográfica de Guanambi/Bahia. Foram construídas curvas Receiver Operating Characteristic (ROC) entre os IO (percentual de gordura - %G; índice de adiposidade corporal – IAC; índice de massa corporal – IMC) e a SM. O equilíbrio entre sensibilidade e especificidade definiu os melhores pontos de corte preditores da SM pelos IO. Os três IO apresentaram capacidade preditiva para SM (curva ROC significativamente > 0,5). Entre as mulheres, o %G apresentou área sob a curva ROC (0,69 - IC95%: 0,65:0,73) significativamente maior que os demais IO. Entre os homens as áreas do %G e do IMC foram iguais (0,81 - IC95%: 0,76:0,85) e maiores que a do IAC. Os melhores pontos de corte dos IO para identificar a presença da SM respectivamente em mulheres e homens foram: 24,97 e 25,36 kg/m2 para IMC, 34,30 e 26,14% para IAC e 37,7 e 23,8% para %G. Os IO testados são válidos para rastrear a SM em adultos quilombolas a partir da utilização dos pontos de corte específicos para a população estudada.
12
Rodríguez Feliciano, Miguel Ángel, Néstor Rodolfo García Chong, Carlos Alberto Castro Salgado, and Luis Enrique Estrada Castillo. "Características antropométricas del adulto mayor con actividad física en Tuxtla Gutiérrez, Chiapas (México) durante el 2020." Ciencia Latina Revista Científica Multidisciplinar 6, no. 6 (December 7, 2022): 4237–648. http://dx.doi.org/10.37811/cl_rcm.v6i6.3771.
Full textAbstract:
Los adultos mayores muestran patologías que afectan su salud y calidad de vida, debido a estilos de vida pocos saludables, presentando parámetros antropométricos elevados. Objetivo: Identificar las características antropométricas (IMC/ICC) y asociarlas con los hábitos de vida saludable de adultos mayores con actividad física en Tuxtla Gutiérrez, Chiapas. Metodología: Estudio transversal, prospectivo, observacional y descriptivo. Participaron 30 adultos mayores de 60 años, aleatoriamente. Se trabajó con variables edad, sexo, hábitos de vida saludable y estado nutricional. Resultados: El 53% presenta sobrepeso, 7% obesidad clase I y 27% obesidad clase II, y el 77% presenta riesgo alto de padecer enfermedades cardiovasculares y/o metabólicas. En ninguna de las variables estudiadas se encontraron diferencias estadísticas significativas con relación al IMC e ICC. Fueron preponderantes el sexo masculino y el grupo de 60 a 63 años con sobrepeso (37% y 23% respectivamente), además de riesgo alto de padecer enfermedades cardiovasculares y/o metabólicas (53% y 27% respectivamente). Conclusiones: El adulto mayor que realiza actividad física, presenta buenos hábitos de vida saludable y estado nutricional, se observa una tendencia hacia el sobrepeso (IMC), así como riesgo alto de padecer enfermedades cardiovasculares y/o metabólicas (ICC), principalmente en varones y en el grupo de 60 a 63 años.
13
Komiyama, Sohtaro, Shohji Kudoh, Katsuko Matsui, Hiromoto Mizoguchi, Hiroshi Miyazaki, and Nobuyoshi Shimizu. "Heterogeneity in Epidermal Growth Factor Responsiveness and Tumor Growth of Human Maxillary Cancer Cell Lines." Annals of Otology, Rhinology & Laryngology 101, no. 6 (June 1992): 519–24. http://dx.doi.org/10.1177/000348949210100613.
Full textAbstract:
We have established three cell lines (IMC-2, IMC-3, and IMC-4) from a human maxillary tumor, which exhibited different sensitivities to epidermal growth factor (ECF). It was inhibitory to colony-forming abilities of IMC-3 and IMC-4 cells in culture, while it affected that of IMC-2 cells slightly if at all. The differential sensitivities to EGF among the three cell lines were reproducibly observed when several cell sublines were further established from tumors appearing in nude mice. Saturation-binding kinetics with 125I-EGF showed similar levels of EGF-binding activities among the three cell lines. However, IMC-2, IMC-3, and IMC-4 showed almost similar sensitivities to cisplatin. Autophosphorylation of EGF receptor in the presence of EGF proceeded at similar levels among the three cell lines. Tumor growth was followed in nude mice when IMC-2, IMC-3, and IMC-4 at 1 × 107 cells were inoculated. The IMC-2 tumors enlarged at much faster rates than the other two cell lines. The IMC-4 tumors showed very slow growth rates, and IMC-3 tumors enlarged at an intermediate rate. These data suggest that the maxillary tumor used comprised cell populations that differed in their growth behaviors in response to EGF.
14
Estaswara, Helpris. "Tiga Dekade Perkembangan Integrated Marketing Communications (IMC): Sebuah Literatur Review." Gunahumas 1, no. 2 (January 26, 2020): 199–213. http://dx.doi.org/10.17509/ghm.v1i2.23042.
Full textAbstract:
Abstrak Sejak kelahirannya, tiga dekade yang lalu hingga hari ini, IMC (Integrated Marketing Communications) telah menjadi perhatian para akademisi dan praktisi di seluruh dunia. Sebagai kajian yang relatif baru, penting untuk meninjau perkembangan IMC yang ditelusuri dari berbagai tulisan yang diterbitkan di jurnal-jurnal internasional terindeks sebagai bentuk manifestasi perkembangannya. Guna melihat perkembangan IMC selama tiga dekade ini dapat didasarkan pada tiga aspek, yaitu theoretical building, topik penelitian dan pengimplementasian IMC. Tujuannya untuk: (1) Melihat sejauhmana perkembangan IMC jika dilihat dari ketiga aspek tersebut dengan membandingkan deskripsi perkembangan sebelum tahun 2005? (2) Aspek apa yang berkembang paling signifikan sehingga beda dengan gambaran perkembangan IMC sebelum tahun 2008? Tahun 2005 dan 2008 dijadikan patokan karena pada saat itu riset perkembangan IMC secara teoretis (2005) dan topik-topik penelitian serta implementasinya (2008) telah dipublikasikan. Dengan menggunakan kajian literatur, penelitian ini menyimpulkan bahwa IMC terus berkembang secara teoretis, namun demikian tidak meninggalkan gagasan dasar yang telah dibangun pada tahun 2005. Hingga kini, teorisasi IMC semakin memertajam bangunan kontruksnya dan lebih bersifat multi-disipliner. Kata Kunci: Perkembangan IMC, Teorisasi IMC, Topik penelitian, Implementasi IMC Abstract Since its inception, three decades ago until today, IMC (Integrated Marketing Communications) has become attention of academics and practitioners around the world. As a relatively new concept, it is important to review the development of IMC which is traced from various papers published in international journals indexed as a manifestation of its development. To identify the development of IMC over the past three decades, it can be based on three aspects, namely theoretical building, research topics, and IMC implementation. Aim of this article is to: (1) Describe IMC development that is viewed from three aspects by comparing before 2005? (2) What aspect is developed most significantly so that it is different from the description of IMC development before 2008? Year 2005 and 2008 were used as benchmarks because at that time research on development of IMC theoretical (2005), research topics, and its implementation (2008) had been published. Using literature review, this research concludes that the IMC continues to develop theoretically, but did not abandon the basic ideas that had been built in 2005. Hitherto, theorization of IMC has sharpened in its construct and become more multi-disciplinary in nature. Keywords: IMC development, IMC theorization, research topics, IMC implementation,
15
Bruhn, Manfred, and Stefanie Schnebelen. "Integrated marketing communication – from an instrumental to a customer-centric perspective." European Journal of Marketing 51, no. 3 (April 10, 2017): 464–89. http://dx.doi.org/10.1108/ejm-08-2015-0591.
Full textAbstract:
Purpose Despite decades of scientific and practical experience in the field of integrated marketing communication (IMC), little is known about the role of IMC in the era of new media. The purpose of the present paper is to undertake a first step to close this gap by proposing thought-provoking impulses for customer-centric IMC. This is done by discussing central premises of customer-centric IMC in terms of the changed conditions on the media markets, its challenges and principles and its implementation issues. Design/methodology/approach The paper provides a conceptual approach to customer-centric IMC by deriving new lines of thinking from a review of existing literature relating to the concept of IMC. Findings The paper positions customer-centric IMC as an important advancement of IMC. It shows that the most important new lines of thinking which could be adopted as strategic components of customer-centric IMC are relationship orientation, content orientation and process orientation. The paper thus suggests that customer-centric IMC is a balancing act between a company’s own branding activities and the integration of customer-centered issues. Originality/value The originality of this paper resides in a detailed conceptual discussion of new insights into a customer-centric IMC. In contrast to existing work on IMC, this paper threads together the existing perspectives on IMC (inside-out and outside-in) to highlight the potential role of IMC in the era of social media (customer-centric IMC) by adding an outside-out view to the concept of IMC.
16
Domínguez-Reyes, Teresa, Irma Quiroz-Vargas, Aralia Berenice Salgado-Bernabé, Lorenzo Salgado-Goytia, José Francisco Muñoz-Valle, and Isela Parra-Rojas. "Las medidas antropométricas como indicadores predictivos de riesgo metabólico en una población mexicana." Nutrición Hospitalaria 34, no. 1 (February 1, 2017): 96. http://dx.doi.org/10.20960/nh.983.
Full textAbstract:
Introducción: actualmente se considera que la acumulación de grasa corporal a nivel central se asocia con la presencia de hipertrigliceridemia, hipertensión arterial y diabetes. El índice de masa corporal (IMC) se ha utilizado para identificar la obesidad en la población general, pero no permite determinar la distribución de la grasa corporal, por lo que se pueden utilizar otras medidas antropométricas para evaluar la adiposidad y determinar su relación con la presencia de alteraciones metabólicas que presentan las personas con exceso de peso.Objetivo: evaluar las medidas antropométricas como el índice cintura-cadera (ICC), IMC y circunferencia de cintura (CC) como indicadores predictivos de factores de riesgo metabólico en población mexicana adulta. Métodos: se realizó un estudio transversal descriptivo en un total de 490 personas (27-46 años), agrupadas por género. A todos los participantes se les determinaron medidas antropométricas y parámetros bioquímicos. Se crearon curvas ROC de los parámetros antropométricos para identificar el mejor indicador predictivo de riesgo metabólico.Resultados: el factor de riesgo metabólico con mayor prevalencia después de la obesidad abdominal en mujeres fue la hipertrigliceridemia, seguido de la hiperglicemia, hipercolesterolemia y presión arterial elevada, que se encontraron con mayor frecuencia en los hombres, aunque la presencia de obesidad abdominal se encontró con mayor frecuencia en las mujeres (73,9 vs.37,3 %). La circunferencia de cintura fue el mejor indicador predictivo para presentar uno o más factores de riesgo metabólico [área bajo la curva ABC = 0,85 (IC 95%, 0,78-0,92)], seguido del IMC [ABC = 0,79 (IC 95%, 0,72-0,88)] y por último el ICC [ABC = 0,63 (IC 95%, 0,52-0,74)]. Además, se observó que la obesidad abdominal duplica el riesgo de presentar el síndrome metabólico.Conclusión: la circunferencia de cintura es el mejor indicador de riesgo metabólico en ambos sexos en comparación con el IMC y el ICC.
17
Nagai, Noriaki, Fumihiko Ogata, Mizuki Yamaguchi, Yuya Fukuoka, Hiroko Otake, Yosuke Nakazawa, and Naohito Kawasaki. "Combination with l-Menthol Enhances Transdermal Penetration of Indomethacin Solid Nanoparticles." International Journal of Molecular Sciences 20, no. 15 (July 25, 2019): 3644. http://dx.doi.org/10.3390/ijms20153644.
Full textAbstract:
This study designed the transdermal formulations containing indomethacin (IMC)—1% IMC was crushed with 0.5% methylcellulose and 5% 2-hydroxypropyl-β-cyclodextrin by the bead mill method, and the milled IMC was gelled with or without 2% l-menthol (a permeation enhancer) by Carbopol® 934 (without menthol, N-IMC gel; with menthol, N-IMC/MT gel). In addition, the drug release, skin penetration and percutaneous absorption of the N-IMC/MT gel were investigated. The particle sizes of N-IMC gel were approximately 50–200 nm, and the combination with l-menthol did not affect the particle characterization of the transdermal formulations. In an in vitro experiment using a Franz diffusion cell, the skin penetration in N-IMC/MT gel was enhanced than the N-IMC gel, and the percutaneous absorption (AUC) from the N-IMC/MT gel was 2-fold higher than the N-IMC gel. On the other hand, the skin penetration from the N-IMC/MT gel was remarkably attenuated at a 4 °C condition, a temperature that inhibits all energy-dependent endocytosis. In conclusion, this study designed transdermal formulations containing IMC solid nanoparticles and l-menthol, and found that the combination with l-menthol enhanced the skin penetration of the IMC solid nanoparticles. In addition, the energy-dependency of the skin penetration of IMC solid nanoparticles was demonstrated. These findings suggest the utility of a transdermal drug delivery system to provide the easy application of solid nanoparticles (SNPs).
18
Song, Soonbum, and Youngmin Kim. "Novel In-Memory Computing Adder Using 8+T SRAM." Electronics 11, no. 6 (March 16, 2022): 929. http://dx.doi.org/10.3390/electronics11060929.
Full textAbstract:
Von Neumann architecture-based computing systems are facing a von Neumann bottleneck owing to data transfer between separated memory and processor units. In-memory computing (IMC), on the other hand, reduces energy consumption and improves computing performance. This study explains an 8+T SRAM IMC circuit based on 8+T differential SRAM (8+T SRAM) and proposes 8+T SRAM-based IMC full adder (FA) and 8+T SRAM-based IMC approximate adder, which are based on the 8+T SRAM IMC circuit. The 8+T SRAM IMC circuit performs SRAM read and bitwise operations simultaneously and performs each logic operation parallelly. The proposed IMC FA and the proposed IMC approximate adder can be applied to a multi-bit adder. The two adders are based on the 8+T SRAM IMC circuit and thus read and compute simultaneously. In this study, the 8+T SRAM IMC circuit was applied to the adder, leveraging its ability to perform read and logic operations simultaneously. According to the performance in this study, the 8+T SRAM IMC circuit, proposed FA, proposed RCA, and proposed approximated adder are good candidates for IMC, which aims to reduce energy consumption and improve overall performance.
19
Carrasco Poyatos, María, and Manuel Vaquero Abellán. "Mejora de la capacidad de salto en mujeres postmenopáusicas con moderado riesgo de fractura de cadera tras dos años de ejercicio en el medio acuático (Results of two years of water training on jump height in postmenopausal women with moderate hip risk fra." Retos, no. 17 (March 9, 2015): 25–29. http://dx.doi.org/10.47197/retos.v0i17.34663.
Full textAbstract:
La finalidad del presente estudio fue establecer el efecto de un programa de impacto y resistencias adicionales en el medio acuático sobre la capacidad de salto en mujeres postmenopáusicas con moderado riesgo de fractura de cadera. 39 mujeres fueron asignadas a tres grupos: grupo de natación (GN; n = 17), grupo de impacto y resistencias (GIR; n = 14) y grupo control (GC; n = 8). Se llevó a cabo un test de composición corporal, mediante el que se analizó el índice de masa corporal (IMC) y el índice cintura-cadera (ICC); y un test de capacidad de salto, en el que se realizó un salto con contramovimiento (CMJ). GN mostró un descenso significativo (p<0.05) en el ICC (5.81%). GIR mejoró significativamente el IMC (3.65%) y el CMJ (15.5%). Dos años de ejercicio de impacto y resistencias adicionales en el medio acuático pueden mejorar la capacidad de salto de mujeres postmenopáusicas con moderado riesgo de fractura de cadera. Tanto este programa de ejercicio como el de natación pueden ofrecer cambios positivos en la composición corporal de dichas mujeres.Palabra clave: postmenopausia, capacidad de salto, medio acuático, composición corporal.Abstract: The aim of the present study was to investigate the effect of a water-based calisthenics and resistance program on jump height in postmenopausal women with moderate hip risk fracture. 39 women were divided into three groups: swimming group (GN; n = 17), calisthenics and resistance group (GIR; n = 14), and control group (GC; n = 8). Body composition test included body mass index (IMC) and waist to hip ratio (ICC). Jump height was assessed by a countermovement jump (CMJ). GN showed a significant (p<0.05) decrease in ICC (5.81%). GIR showed a significant decrease in IMC (3.65%) and a significant increase in CMJ (15.5%). Two years of water-based calisthenics and resistance training can offer significant benefits in jump height in postmenopausal women with moderate hip risk fracture. Both exercise programs can also improve body composition.Key words: postmenopausal period, jump height, resistance training, body compositions.
20
Soares, Daniela Arruda, and Sandhi Maria Barreto. "Indicadores nutricionais combinados e fatores associados em população Quilombola no Sudoeste da Bahia, Brasil." Ciência & Saúde Coletiva 20, no. 3 (March 2015): 821–32. http://dx.doi.org/10.1590/1413-81232015203.03922014.
Full textAbstract:
Este estudo estimou a prevalência de duas combinações de indicadores nutricionais: Índice de Massa Corporal (IMC) + Circunferência da Cintura (CC) e IMC + Razão Cintura Estatura (RCE), e investigou os fatores associados em adultos Quilombolas. Amostra aleatória em dois estágios de 739 adultos ≥ 20 anos, residentes em Comunidades Quilombolas em Vitória da Conquista (BA), em 2011. Risco combinado IMC + RCE incluiu os indivíduos que simultaneamente apresentaram IMC ≥ 25,0Kg/m2 ou ≥ 27,0Kg/m2, se idade ≥ 60 anos e RCE ≥ 0,5. O risco IMC + RCE incluiu indivíduos com IMC elevado que também apresentavam CC ≥ 80cm, se mulher, ou ≥ 94cm, se homem. As prevalências dos indicadores nutricionais combinados foram de 35,3% (IMC + RCE) e 26,8% (IMC + CC). Sexo feminino e hipertensão aumentaram a chance para os dois indicadores enquanto que o estado civil não casado diminuiu esta chance. O indicador IMC + RCE foi maior na faixa etária de 40 a 59 anos e o indicador IMC + CC foi mais frequente na faixa de 40 a 49 anos. A baixa escolaridade elevou o indicador IMC + RCE, enquanto assistir televisão por mais de duas horas por dia, o indicador IMC + CC. A elevada prevalência de risco nutricional para DCNT, especialmente de obesidade central, confirmou a necessidade de ações de promoção de dieta saudável e saúde.
21
Arfaoui, H., A. Fahmi, H. Jabri, W. Elkhattabi, and H. Afif. "BPCO et IMC." Revue des Maladies Respiratoires Actualités 13, no. 1 (January 2021): 92–93. http://dx.doi.org/10.1016/j.rmra.2020.11.185.
Full text
22
Rau, Hans, and Karl-Heinz Stump. "IMC-PUR-Sprühtechnologie." ATZextra 13, no. 10 (December 2008): 106–13. http://dx.doi.org/10.1365/s35778-008-0223-x.
Full text
23
Laurie, Sally, and Kathleen Mortimer. "‘IMC is dead. Long live IMC’: Academics' versus practitioners' views." Journal of Marketing Management 27, no. 13-14 (December 2011): 1464–78. http://dx.doi.org/10.1080/0267257x.2011.627367.
Full text
24
Schultz, Don E., and Charles H. Patti. "The evolution of IMC: IMC in a customer-driven marketplace." Journal of Marketing Communications 15, no. 2-3 (July 2009): 75–84. http://dx.doi.org/10.1080/13527260902757480.
Full text
25
Arias, Clever, Rubén Valdivieso, Marco Núñez, Miriam Inga, Felipe Sosa, and Oscar Acosta. "Evaluación del índice de masa corporal y su relación con la hiperglucemia en pacientes diabéticos tipo 2, en Lima Metropolitana, durante el año 2011." Anales de la Facultad de Medicina 73 (May 7, 2013): 48. http://dx.doi.org/10.15381/anales.v73i1.2224.
Full textAbstract:
Objetivos: Establecer una correlación entre IMC e hiperglicemia entre pacientes con diabetes mellitus tipo 2. Diseño: Observacional con sistema de medición, descriptivo. Institución: Departamento Académico de Ciencias Dinámicas, Facultad de Medicina, UNMSM. Participantes: Pacientes con diabetes mellitus tipo 2. Intervenciones: Se desarrolló encuestas socio- económicas a 300 pacientes con diabetes mellitus tipo 2, además de las medidas antropométricas; posterior a ello se tomó una muestra de sangre para los análisis bioquímicos. Principales medidas de resultados: Peso, talla, IMC, índice cintura cadera (ICC), glucosa mg%, triglicéridos mg%. Resultados: De los 300 pacientes encuestados, 58,8% correspondió al género masculino; 41,2% tenía educación primaria, 44,1% educación secundaria y 14,7% educación superior. El 34% de la población presentó hiperglucemia, 58% obesidad de primer y segundo grado, 17,6% sobrepeso y 23,6% peso normal. El 64,7% de los pacientes no desarrollaba dieta alguna, 64,7% no tenía consejería diabética, 59% no desarrollaba actividad física y presentó hiperglucemia. El 35% de los pacientes tenía control mensual de la enfermedad y sus niveles de glucosa estaban en los valores normales. Encontramos una correlación IMC / niveles de glucosa con la ayuda del coeficiente de Pearson = 0,524, p < 0,01. Conclusiones: La relación IMC/ glicemia tuvo un coeficiente de Pearson = 0,524, p < 0,01, mostrando correlación moderadamente significativa para los indicadores.
26
Nagai, Noriaki, Takumi Isaka, Saori Deguchi, Misa Minami, Mizuki Yamaguchi, Hiroko Otake, Norio Okamoto, and Yosuke Nakazawa. "In Situ Gelling Systems Using Pluronic F127 Enhance Corneal Permeability of Indomethacin Nanocrystals." International Journal of Molecular Sciences 21, no. 19 (September 25, 2020): 7083. http://dx.doi.org/10.3390/ijms21197083.
Full textAbstract:
We previously designed an ophthalmic dispersion containing indomethacin nanocrystals (IMC-NCs), showing that multiple energy-dependent endocytoses led to the enhanced absorption of drugs from ocular dosage forms. In this study, we attempted to prepare Pluronic F-127 (PLF-127)-based in situ gel (ISG) incorporating IMC-NCs, and we investigated whether the instillation of the newly developed ISG incorporating IMC-NCs prolonged the precorneal resident time of the drug and improved ocular bioavailability. The IMC-NC-incorporating ISG was prepared using the bead-mill method and PLF-127, which yielded a mean particle size of 50–150 nm. The viscosity of the IMC-NC-incorporating ISG was higher at 37 °C than at 10 °C, and the diffusion and release of IMC-NCs in the IMC-NC-incorporating ISG were decreased by PLF-127 at 37 °C. In experiments using rabbits, the retention time of IMC levels in the lacrimal fluid was enhanced with PLF-127 in the IMC-NC-incorporating ISG, whereby the IMC-NC-incorporating ISG with 5% and 10% PLF-127 increased the transcorneal penetration of the IMCs. In contrast to the results with optimal PLF-127 (5% and 10%), excessive PLF-127 (15%) decreased the uptake of IMC-NCs after instillation. In conclusion, we found that IMC-NC-incorporating ISG with an optimal amount of PLF-127 (5–10%) resulted in higher IMC corneal permeation after instillation than that with excessive PLF-127, probably because of the balance between higher residence time and faster diffusion of IMC-NCs on the ocular surface. These findings provide significant information for developing ophthalmic nanomedicines.
27
Chua, Kok Yau, May Ting Hng, Cher Chia Lee, and T. Joseph Sahaya Anand. "XRD Analysis of Cu-Al Interconnect Intermetallic Compound in an Annealed Micro-Chip." Advanced Materials Research 620 (December 2012): 166–72. http://dx.doi.org/10.4028/www.scientific.net/amr.620.166.
Full textAbstract:
Cu-Al intermetallic compound (IMC) in Cu wire-Al bond pad interconnect interface is drawing attention of researches. However, due to thin IMC thickness, the characterizations of the IMC are limited to expensive and time consuming techniques. An evaluation is performed to use common X-Ray Diffraction (XRD) technique to identify the IMC in the Cu wired micro-chip samples in powder form. Existence of mixture of CuAl and CuAl2 was first confirmed by transmission electron microscope (TEM) and energy dispersive X-ray (EDX). In XRD analysis, peak correspond to CuAl phase is identified from measurement with slower scan configuration. The difficulty for IMC peak detection in diffractogram is due to low composition ratio of IMC relative to other materials available in the sample. KOH treatment for enhancing IMC peaks intensity does not work as expected as it etches the IMC as well.
28
Pringgowati, Nurul. "EVALUASI INTERGRATED MARKETING COMMUNICATION DISBUDPAR DAN DISPORAPAR DALAM MENYIAPKAN KOTA MALANG SEBAGAI TOURISM HUB TAHUN 2019-2020." JURNAL HERITAGE 9, no. 1 (June 30, 2021): 1–19. http://dx.doi.org/10.35891/heritage.v9i1.2383.
Full textAbstract:
Abstrak: Disbudpar 2019 dan Disporapar 2020 mengupayakan penerapan IMC dalam menyiapkan Kota Malang sebagai tourism hub. Namun, belum ada data empiris tentang bagaimana implementasi dari elemen IMC yang dilakukan. Tujuan penelitian ini adalah menganalisis dan mengevaluasi penerapan IMC dalam menyiapkan Kota Malang sebagai tourism hub. Menggunakan metodologi penelitian kualitatif melalui wawancara, observasi dan studi dokumen. Penelitian ini memanfaatkan IMC dalam menganalisis data penelitian. Hasil penelitian menunjukkan bahwa terdapat aktifitas implementasi IMC yang dilakukan oleh Disbudpar dan Disporapar , namun pada prosesnya perlu meningkatkan sinergi dan sosialisasi arah penerapan IMC kepada pelaku usaha wisata untuk membangun kesepahaman ekosistem pariwisata dalam proses pemasaran pariwisata menjadi tourism hub. Penelitian ini merekomendasikan peningkatan sinergitas model Pentahelix ABGCM dan melakukan pembinaan serta sosialisasi penerapan IMC kepada pelaku wisata.
29
Ren, Hang, Tao Hu, Yu Song, Hui Sun, Bo Liu, and Ming Gao. "An Improved Electronic Image Motion Compensation (IMC) Method of Aerial Full-Frame-Type Area Array CCD Camera Based on the CCD Multiphase Structure and Hardware Implementation." Sensors 18, no. 8 (August 11, 2018): 2632. http://dx.doi.org/10.3390/s18082632.
Full textAbstract:
In this paper, the performance of the electronic conventional image motion compensation (IMC) method based on the time delay integration (TDI) mode was analyzed using the optical injection formula of charge coupled devices (CCDs). The result shows that the non-synchronous effect of charge packet transfer caused by line-by-line transfer during exposure makes the compensated image dissatisfying. Then an improved electronic IMC method based on the CCD multiphase structure was proposed. In this method, a series of proper driving clocks were applied to drive the charge packet to move electrode-by-electrode during the exposure time, which results in a minimum non-synchronous effect of charge packet transfer. The mismatch of velocity between charge packet transfer and image motion was decreased. The performance of the improved electronic IMC method was also analyzed using the optical injection formula. The modulation degrees of the two methods were compared. The average value of the modulation degree of the improved electronic IMC method was 47/96, greater than the conventional electronic IMC method, which was 1/3. To achieve the improved electronic IMC, the driver timing diagram of the improved electronic IMC method was proposed. This paper presented an improved hardware implementation method for the improved electronic IMC method. Based on the basic FTF4052M drive circuit system, an IMC pulse pattern generator that worked together with the main pulse pattern generator (SAA8103) was added to achieve the improved electronic IMC. Then, the internal structure of the IMC pulse pattern generator was given. A dual pulse pattern generator drive circuit system was proposed. After computer simulation and indoor real shot verification, the compensation effect of the improved electronic IMC method was better than the compensation effect of the conventional electronic IMC method.
30
Higano, C., J. Alumkal, C. J. Ryan, E. Y. Yu, T. M. Beer, K. Chandrawansa, T. Katz, H. Youssoufian, and J. Schwartz. "A phase II study evaluating the efficacy and safety of single agent IMC A12, a monoclonal antibody (MAb), against the insulin-like growth factor-1 receptor (IGF-IR), as monotherapy in patients with metastastic, asymptomatic castration-resistant prostate cancer (CRPC)." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): 5142. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.5142.
Full textAbstract:
5142 Background: IGF-IR-mediated signaling contributes to prostate cancer carcinogenesis and pathogenesis and may be associated with hormone resistance. IMC-A12 is a fully human IgG1 MAb that specifically targets the IGF-IR and inhibits ligand binding and signaling. In xenografts, IMC-A12 inhibits growth of both androgen-dependent and -independent prostate cancer. This phase 2, multicenter study was designed to assess the safety and antitumor activity of IMC-A12 in asymptomatic pts with metastatic CRPC who were chemotherapy-naive. Methods: Pts received IMC-A12 10 mg/kg IV every 2 wks; until evidence of progressive disease (PD), intolerable toxicity, or other withdrawal criteria were met. Radiologic evaluation was performed every 8 wks. PD by bone scan required at least 2 new lesions with confirmation at subsequent imaging per PCWG2. Results: 19 of 31 pts treated have discontinued IMC-A12, 12 due to PD. 9 of 31 pts experienced disease stabilization for ≥6 mos (range: 7.4–12.5 mos), 5 pts (3 with PSA reduction) continue on IMC-A12. The most common AEs possibly or probably related to IMC-A12, were fatigue (25.8%) and hyperglycemia (19.4%). In 4 pts cases of Grade 3 hyperglycemia was treatment related none requiring discontinuation of IMC-A12; 1 pt required insulin but continued on study. Approximately 70% of pts experienced at least transient elevation of nonfasting glucose to above normal range. Other AEs grade ≥3 at least possibly related to IMC-A12 were one case each of thrombocytopenia (requiring IMC-A12 discontinuation), hyperkalemia, fatigue, pneumonia (resulting in death), and Grade 4 pharmacokinetic and pharmacodynamic analayses are pending leukoencephalopathy (probably related; requiring IMC-A12 discontinuation). Pharmakinetic and pharmacodynamic analyses are pending. Conclusions: IMC-A12 monotherapy appears well tolerated in pts with metastatic asymptomatic CRPC. As in phase I, hyperglycemia was largely asymptomatic and manageable. Disease stabilization for > 6 months in 9 of 31 pts suggests that IMC- A12 may have modest antitumor activity. Additional studies of IMC-A12 in CRPC are planned. [Table: see text]
31
Kerr, Gayle, and Louise Kelly. "IMC education and digital disruption." European Journal of Marketing 51, no. 3 (April 10, 2017): 406–20. http://dx.doi.org/10.1108/ejm-08-2015-0603.
Full textAbstract:
Purpose The purpose of this paper is to benchmark the progress of integrated marketing communication (IMC) education, by replicating and extending a study on IMC education by Kerr (2009). It documents progress, examines the impact of digital disruption and concludes with an agenda for change. Design/methodology/approach Using the Delphi technique, this study recruited leading IMC educators and thought leaders internationally to find consensus on an important range of IMC issues, including its place within the university, the IMC brand, curriculum, impact on practice, the incorporation of digital and future challenges. Findings IMC has strengthened its place within the university and also within the minds and understanding of academics, students and industry. Digital disruption provides many challenges including updating curriculum and up skilling staff. It is vital, however, that IMC thinking be positioned as the integrator and digital as the facilitator, providing platforms to actualise IMC strategy such as content, customer service and cross-functional planning. Practical implications This study shows what IMC education has achieved since Kerr’s (2009) study. Further, it outlines what needs to be achieved in the future by providing a “To do” list for IMC educators. Originality/value It is vital that the development and progress of this important new area of study is tracked to ensure industry challenges are met, such as digital disruption, and the right education for IMC managers of the future is provided.
32
Garber, Jr, Lawrence L., Kacy Kim, and Michael J. Dotson. "The IMC mixes that trucking managers use." Journal of Business & Industrial Marketing 35, no. 12 (May 15, 2020): 2067–77. http://dx.doi.org/10.1108/jbim-05-2018-0173.
Full textAbstract:
Purpose This paper aims to test the proposition that integrated marketing communications (IMC) practice is lagging in the trucking industry. It stems from the more general proposition extant in the literature that business to business (B2B) IMC practice lags business to consumer IMC practice. Design/methodology/approach In total, 109 trucking managers attending the American Trucking Association Annual Management Conference are asked which communications tools they use and for which strategic purposes. The new product adoption model (NPAM) provides a means of measuring efficient IMC practice. Findings Joint space perceptual maps generated by correspondence analysis reveal the association between trucking managers’ IMC mixes and the stages of the NPAM. Inspection shows that trucking managers deploy a relatively large number of traditional and digital tools to support all stages of the NPAM, indicating a sophisticated level of IMC knowledge and practice, contrary to the proposition that IMC practice is lagging in the trucking industry. Originality/value This contrary result suggests that IMC practice proceeds at different rates across B2B industries and must be examined on a per-industry basis. In combination with Garber and Dotson’s (2002) trucking IMC study, this study provides a second data point from which the evolution of IMC practice in the trucking industry can be tracked into the future. Additionally, this paper demonstrates the efficacy of the NPAM as a means of measuring the efficiency of IMC mixes, as well as for monitoring and training. Theoretical and managerial implications are discussed.
33
Jones, Vickie, Shohei Yoshida, Makiko Kobayashi, David Herndon, and Fujio Suzuki. "CD34+CD31+ immature myeloid cells (IMC) as an inhibitor cell on the production of antimicrobial peptide: I. Inhibitory activities of CD34+CD31+ IMC on the antimicrobial peptide production by keratinocytes (89.31)." Journal of Immunology 184, no. 1_Supplement (April 1, 2010): 89.31. http://dx.doi.org/10.4049/jimmunol.184.supp.89.31.
Full textAbstract:
Abstract CD34+CD31+ IMC, isolated from peripheral blood of exercised donors, are shown to be inhibitor cells on HBD-1 production by normal human epidermal keratinocytes (NHEK). Lineage cell-depleted PBMC were isolated from peripheral blood of healthy donors 24 hrs after 1-hr of treadmill exercise using a lineage cell depletion kit, then CD34+CD31+ IMC were sorted from these cells by flow cytometry. IMC were transwell-cultured with NHEK for 48 hrs, and NHEK harvested were analyzed for HBD-1 mRNA expression by RT-PCR. Also, conditioned media harvested 48 hrs after the cultivation of CD34+CD31+ IMC (IMC-culture media) were assayed for their inhibitory activities on HBD-1 production by NHEK. In the results, HBD-1 mRNA expression by NHEK was completely inhibited after transwell-cultivation with CD34+CD31+ IMC. HBD-1 was not detected in NHEK cultures supplemented with 20 to 40% of IMC-culture media. IL-10 and CCL2 were detected in the IMC-culture media. When NHEK were cultured with the IMC-culture media previously treated with a mixture of anti-CCL2 and anti-IL-10 mAbs, HBD-1 was produced in their culture fluids. These results indicate that CD34+CD31+ IMC transiently appearing in peripheral blood of exercised donors are inhibitory on HBD-1 production by NHEK. CCL2 and IL-10 produced by these cells are required on the CD34+CD31+ IMC-mediated inhibition of HBD-1 production by NHEK. This study was supported by SHC #8610.
34
Lutiyatmi, Lutiyatmi, and Tri Daryanto. "Pengaruh Proses Degassiing pada Peleburan Aluminium dengan Tungku Peleburannya." Automotive Experiences 1, no. 03 (December 19, 2018): 70–76. http://dx.doi.org/10.31603/ae.v1i03.2360.
Full textAbstract:
Porositas gas adalah salah satu masalah yang paling serius dalam pengecoran logam aluminium. Ada beberapa metode degassiing yang telah dipelajari dalam proses pengecoran. Selama peleburan aluminium, senyawa intermetalik (IMC) dapat dibentuk pada antarmuka antara aluminium cair dan baja padat dari lapisan tungku krusibel. Dalam penelitian ini, efek penambahan degassiing dari formasi IMC dipelajari dan diteliti. Spesimen uji berbentuk silinder direndam dalam bak aluminium cair. Perendaman spesimen uji berada di kisaran waktu antara 10 sampai 15 menit. Dua penggunaan degassiing yaitu degassiing garam dapur grasak dan degassiing Natrium Clorida (NaCl) dilakukan untuk menyelidiki efek pada pembentukan IMC. IMC itu diperiksa di bawah miskroskop elektron serta kekerasan IMC dengan mikrovickers hardness. Karena tingginya kandungan hidrogen, spesimen uji yang direndam dalam aluminium cair tanpa degasser memiliki lapisan IMC yang lebih tebal daripada yang lain. Proses degassiing NaCl lebih efektif daripada degassiing garam Grasak untuk mengurangi pertumbuhan IMC. Selanjutnya, fase yang muncul pada daerah IMC yaitu senyawa FeAl dan FeAl3 terbentuk pada spesimen dengan proses tanpa degassiing dan menggunakan degassiing NaCl.
35
Kuebler, H. R., J. Dannull, T. Y. Tseng, A. Zhang, Z. Su, P. Dahm, and J. Vieweg. "Immature myeloid cell (ImC)- mediated immunosuppression in advanced renal cell cancer (RCC)." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 10042. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.10042.
Full textAbstract:
10042 Background: RCC affects the immunsystem by inhibiting the process of differentiation of antigen-resenting cells from their myeloid precursors by secreting tumor-derived factors such as VEGF. ImC induce a profound state of immune suppression that foster tumor tolerance by inhibition of tumor specific T cells. In this study, we asked whether increased ImC frequencies can be found in peripheral blood from RCC patients and if ImC frequencies correlated positively with increased levels of tumor-derived serum markers. Methods: ImC frequencies from healthy volunteers and RCC patients were determined by FACS. ImC were isolated by magnetic bead separation techniques and their immunosuppressive activity was determined in IFN-γ ELISPOT analyses, CTL and T-cell proliferation assays. The production of reactive oxygen species by ImC was analyzed utilizing specific probes and inhibitors. Tumor-derived serum markers were quantified by ELISA, enzyme immune assays and cytometric bead arrays. Microarray analyses were performed to identify novel, highly specific ImC markers. Results: RCC patients demonstrate higher ImC frequencies (0.8 - 3.2% of total PBMC) compared to healthy donors. The increased ImC frequencies are positively correlated with serum levels of VEGF, PGE-2, IL-13 and M-CSF in RCC patients and the concentration of byproducts of oxidative burst, including iso-prostane and malondialdehyde, was significantly enhanced. Isolated ImC exhibited profound immunosuppressive effects on CTL and CD4+ T cell response in an antigen specific fashion. Immunosuppression by ImC was mediated by release of ROS, including peroxide and superoxide anions and by generation of nitric oxide radicals as evidenced in functional assays. Results from microarray analyses reveal EP-1, EphA5, and PEX-5 as novel ImC markers. Conclusions: These data suggest that RCC may induce the development of immunosuppressive ImC population through secretion of cytokines such as VEGF, IL-13, M-CSF and PGE-2. Inhibition of specific cytokine activity or the use of differentiating agents may represent strategies to decrease immunosuppressive ImC population. Results from a phase I clinical trial investigating the effects of all-trans retinoic acid (ATRA) on differentiation of ImC in RCC patients will be presented. No significant financial relationships to disclose.
36
Dahl, Stephan, Lynne Eagle, and David Low. "Integrated marketing communications and social marketing." Journal of Social Marketing 5, no. 3 (July 13, 2015): 226–40. http://dx.doi.org/10.1108/jsocm-07-2012-0031.
Full textAbstract:
Purpose – The purpose of this paper is to examine the view of integrated marketing communications (IMC) by social marketing practitioners. Specifically, the paper furthers the discussion how a symbiotic relationship between IMC and social marketing can lead to both practical improvements of health-related social marketing campaigns, as well as theoretical advancement of the IMC construct. Design/methodology/approach – Based on semi-structured, in-depth interviews with practitioners, the authors provide exploratory evidence for support for IMC within the social marketing community and highlight potential differences and similarities when transferring IMC from a commercial to a social context. Findings – Three main differences emerged when transferring IMC from a commercial to a social context. These include differences of customer-centric approaches between commercial and social marketing, the need to weigh out the application of IMC to the charity brand or the use of IMC at a behavioural level and, finally, different complexity levels of desired behaviour as a mediating factor. Research limitations/implications – As with all qualitative data, the findings may not be generalisable beyond the interview participants and organisations studied. Practical implications – Many practitioners expressed that they liked IMC as a concept, but they lacked guidance as to the application with a social marketing context. This paper contributes to providing this guidance and establishing a body of knowledge how IMC can be applied in a non-commercial setting. Originality/value – The paper contributes to the practical development of guidance how the largely commercially applied IMC construct can be modified to be used in a social marketing context, while correspondingly highlighting how IMC needs to evolve to grow beyond purely commercial application.
37
Abu-Sbeih, Hamzah, Tenglong Tang, David M. Faleck, Michael L. Dougan, Anna Olsson-Brown, Douglas Buckner Johnson, Dwight Hall Owen, et al. "Outcomes of immune checkpoint inhibitor-mediated colitis: Multicenter cohort study." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): 2643. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.2643.
Full textAbstract:
2643 Background: Immune checkpoint inhibitor (ICI)-mediated colitis (IMC) is a common and serious adverse event. Although small series have described the clinical presentation of IMC, large multicenter series that integrate clinical, endoscopic, and histologic findings are lacking. Methods: We retrospectively assessed patients who received ICI and had endoscopically confirmed IMC from 2010 to 2019. IMC was graded based on the CTCAE version 5.0 criteria. Multivariate logistic regression analyses were conducted to assess factors associated with recurrence of IMC symptoms and long duration of corticosteroids use (> 70 days). Results: 675 patients were included. 387 patients were males (57%). Median age was 63 years. Melanoma was the most common cancer type (327; 48%). Most (365; 54%) patients received CTLA-4 inhibitor ICI, as monotherapy or in combination with PD-(L)1. Median time from ICI therapy to IMC was 62 days. IMC was grade 2 in 335 (50%) patients, Grade 3 in 181 (27%), and grade 4 in 16 (3%). 155 (23%) patients had mucosal ulceration on endoscopy, 91 of them had severe features (deep, large, or multiple ulcers); 336 (50%) patients had non-ulcerative inflammation. The rest had normal endoscopic findings with histologic inflammation. Most patients were admitted to the hospital for management of IMC (405; 60%) and 16 (3%) needed ICU-level of care. Treatment included corticosteroids in 577 (85%) patients (median duration 52 days), TNF inhibitor in 245 (36%), and vedolizumab in 90 (13%). 202 (32%) patients had recurrent IMC after resolution of symptoms. On multivariate logistic regression, factors associated with IMC recurrence and long (> 70 days) duration of corticosteroid therapy were grade of IMC ( p = 0.049), treatment with infliximab or vedolizumab ( p = 0.044), presence of mucosal ulceration ( p = 0.034 ), or features of active histologic inflammation ( p = 0.076). Of note, patients with mucosal ulceration received infliximab or vedolizumab more frequently ( p < 0.001). For patients with grade 2 IMC, mucosal inflammation on endoscopy and delay in performing endoscopy with time from IMC onset to endoscopy more than a month were associated with IMC recurrence and longer duration of corticosteroid use ( p = 0.029 and p < 0.001, respectively). 16 (3%) patients had colonic perforation, 7 of them underwent surgical resection. No IMC-related death occurred. Conclusions: IMC is a clinically significant adverse event that can lead to premature termination of ICI therapy with high rates of hospital admission. Rarely, it results in colonic perforation requiring surgical intervention and ICU admission. Our data suggest that there is a utility of endoscopic and histologic evaluation in the prediction of worse outcomes from IMC. This finding is particularly important for grade 2 IMC as current guidelines do not recommend endoscopic evaluation for this group.
38
López Sánchez, G. F., F. J. Borrego Balsalobre, and A. Díaz Suárez. "Efectos de un programa de actividad física en la composición corporal de escolares de 3-5 años." SPORT TK-Revista EuroAmericana de Ciencias del Deporte 2, no. 2 (November 1, 2013): 41. http://dx.doi.org/10.6018/194601.
Full textAbstract:
Objetivos: Este artículo se centra en estudiar los efectos de un programa de actividad física sobre la composición corporal de ungrupo de escolares. Método: Han participado 36 escolares (20 niños y 16 niñas), entre los 3 y los 5 años de edad. Las variables estudiadas han sido: masa grasa, masa libre de grasa, IMC (Índice de Masa Corporal), ICC (Índice Cintura/Cadera). El análisis de la composición corporal se ha realizado mediante bioimpedancia eléctrica, por medio del Monitor de grasa corporal Tanita BC 418-MA Segmental. El procedimiento ha sido: pre-test, intervención y pos-test. La intervención ha consistido en 3 días a la semana de actividad física de alta intensidad, 15 minutos al día, durante 12 semanas. Resultados y conclusiones: Mejoras significativas en la masa grasa (Sig. < 0.05). No se han encontrado mejoras significativas en la masa libre de grasa, el IMC y el ICC.
39
Lee, Kwang Jin, Shinji Kumai, Nobuhiro Ishikawa, and Kazuo Furuya. "Interfacial Microstructure of A6111/Steel Lap Joint Fabricated by Defocused Laser Beam Welding." Materials Science Forum 519-521 (July 2006): 1119–24. http://dx.doi.org/10.4028/www.scientific.net/msf.519-521.1119.
Full textAbstract:
Lap joining of A6111 alloy and steel (SPCC: Steel Plate Cold-rolled C) plates was performed using a defocused YAG laser beam. A detailed investigation was performed on the intermetallic compound (IMC) layer formed at the weld interface. Two representative joints fabricated under different welding conditions were selected and the effect of the welding conditions on the kind and morphology of the IMC was investigated using a transmission electron microscope (TEM). An electron diffraction pattern method was used to identify IMC. It was found that the morphology and kind of IMC formed at the weld interface were strongly affected by the welding conditions, in particular, by the amount of heat input during welding. The thickness of the IMC layer formed at the weld interface was about 1 μm and the average grain size of the IMC in the layer was less than 300 nm when the joining was carried out with a small amount of heat input. The IMC layer was composed of Fe3Al, FeAl, Al2Fe, Al5Fe2 and Al13Fe4 in this case. However, the thickness of the IMC layer was around 6 μm when the joining was carried out under high heat input conditions. In this case, the IMC layer was composed of coarse Al5Fe2 (5 μm) and Al13Fe4 (1 μm). Therefore, it is considered that the reduced bonding strength of the joint with a thick IMC layer is due not only to the overall morphology of the IMC layer but also to the formation of coarse Al-rich IMCs in the layer.
40
Oliveira Hanna, Leila Maués, Juliana De Souza Oliveira, Alynne Caroll Galdina Reis, Jennifer Gomes vaz, and Eduardo Miranda de Oliveira. "Análise nutricional e bucal de gestantes do programa materno infantil do Pará – MINPA." Saúde Coletiva (Barueri) 12, no. 78 (July 15, 2022): 10988–97. http://dx.doi.org/10.36489/saudecoletiva.2022v12i78p10988-10997.
Full textAbstract:
Objetivo: Avaliar o índice de CPOD (dentes cariados, perdidos e obturados) e associá-los ao consumo alimentar e índice de massa corporal (IMC). Método: 31 grávidas fizeram avaliação nutricional para obtenção do IMC e hábitos nutricionais, e avaliação odontológica para obtenção do índice de CPOD. Resultado: 39% das grávidas apresentaram IMC bom, e 61% apresentaram IMC ruim. Das grávidas com IMC bom, 18,18% apresentaram lesão de cárie, 25% tinham elementos obturados e 22,22% apresentavam ausência de algum elemento (perdidos) apenas. Já as grávidas com o IMC ruim, 63,15% apresentavam lesões de caries, 75% tiveram elementos obturados e 77,77% apresentavam ausência de algum elemento (perdidos). Mostrando assim a prevalência de elementos cariados, obturados e perdidos em grávidas que apresentaram o IMC ruim. Estatisticamente, houve significância de 0,046 . Conclusão: Os cuidados e orientações na saúde nutricional e bucal são de extrema importância no período gestacional.
41
Galvin, Robert T., Qing Cao, Weston P. Miller, Angela R. Smith, and Christen L. Ebens. "Immune Mediated Cytopenias Following Allogeneic Hematopoietic Cell Transplantation for Non-Malignant Disease: Risk Factors and Treatment Response in the Pediatric Population." Blood 132, Supplement 1 (November 29, 2018): 3377. http://dx.doi.org/10.1182/blood-2018-99-117718.
Full textAbstract:
Abstract Background: Immune mediated cytopenias (IMC) - isolated or combined hemolytic anemia, thrombocytopenia, and neutropenia - are increasingly recognized as potentially serious complications following allogeneic hematopoietic cell transplantation (HCT) for non-malignant disorders (NMD). However, IMC incidence, severity, response to therapy, and associated risk factors are not well defined. Methods: Pediatric patients undergoing HCT for NMD between 2010 and 2017 at a single institution were identified, excluding those experiencing graft failure or death prior to day +100. Demographics and HCT characteristics were obtained from a prospectively-maintained, institutional database. A retrospective chart review identified cases of IMC with positive direct antiglobulin test, anti-platelet antibody, and/or anti-granulocyte antibody; and documented treatment(s) and response. Composite IMC severity, incorporating peak acuity and response to therapy, was defined as mild (outpatient management with supportive care or a single course of therapy), moderate (outpatient management with 2 or more courses of therapy), or severe (inpatient management with 2 or more courses of therapy). Factors hypothesized to be associated with IMC included younger age, reduced intensity conditioning, mixed or declining donor chimerism, and inherited metabolic disorder as indication for HCT. For the first year after transplant, peripheral blood donor chimerism, B-cell reconstitution, and IgG and IgM levels were obtained. Results: A total of 271 NMD HCT recipients were included, with 53 (20%) exhibiting IMC, 20 (38% of cases) with multiple cell lines affected, diagnosed at a median of 131 days post-HCT (range, 30-264 days). IMC disease was mild, moderate, or severe in 56%, 32%, and 11%, respectively. For those with moderate or severe IMC, all received steroid therapy, with a response rate of 13%. Eighty-seven percent received additional therapy including IVIG, rituximab, bortezomib, and/or vincristine. Resolution of moderate IMC required an average of 2 individualized treatment courses, while severe IMC responded after an average of 6. Notably, no patients died of IMC. Univariate analysis revealed statistically significant association between IMC and younger age at HCT (median 3.1 vs. 7.1 years, p<0.01) and inherited metabolic disorder as the indication for HCT (p<0.01). Patient sex, recipient-donor HLA-match, stem cell graft source, intensity of conditioning, and presence of acute graft-versus-host disease were not significantly different between those with and those without IMC. Following HCT, a decline in peripheral blood donor CD3+ chimerism by at least 10% from day +60 to +100 was more common in those with IMC (p<0.01), although 50% of patients with IMC did not demonstrate a decrease in donor T-cell engraftment. The percent donor CD3+ chimerism at day +100 trended lower in the IMC group compared with the non-IMC group (71% vs 88.5%, p=0.10). The kinetics of patient B cell, IgG, or IgM recovery was not associated with IMC. Conclusion: Immune mediated cytopenias following HCT for NMD in a large pediatric cohort was common at 20%, with nearly half of those affected exhibiting clinically significant courses before disease resolution. Elucidation of risk factors may inform modifications to conditioning regimens or other approaches to prevent IMC. We found younger age at HCT, inherited metabolic disorder as HCT indication, and declining donor T-lymphoid chimerism as risk factors for IMC. However, the pathogenesis of IMC post-HCT for NMD remains elusive. Further insights may arise from investigation into the role of infections/molecular mimicry and complement activation. Disclosures Miller: Sangamo Therapeutics: Employment.
42
Tarraga Lopez, Pedro J. "Análisis de la influencia del Índice de Masa Corporal en la evolución de la Insuficiencia Cardíaca en una Zona de Salud." Revista Española de Nutrición Humana y Dietética 24, no. 2 (July 16, 2020): 103. http://dx.doi.org/10.14306/renhyd.24.2.931.
Full textAbstract:
Introducción: Analizar las diferentes variables del Índice de Masa Corporal (IMC) en relación con la evolución de la Insuficiencia cardíaca en una zona de salud.Material y métodos: Estudio descriptivo observacional y analítico de los 161 pacientes diagnosticados en la zona de salud entre enero de 2014 y diciembre de 2016. Se analizaron datos demográficos, clínicos, y analíticos. Se calculó el IMC a partir del peso y la talla en la primera visita a la consulta, mediante la fórmula: peso (kg) / cuadrado de la talla (m). Una vez obtenido se evaluó la relación entre el IMC y la evolución en 2 años. Se estudió a 4 subgrupos de pacientes, en función de su IMC, a partir de los criterios definidos por la Organización Mundial de la Salud (OMS) en 1999: bajo peso (IMC < 20,5), peso normal (IMC de 20,5 a < 25,5), sobrepeso (IMC de 25,5 a < 30) y obesidad (IMC ≥ 30).Resultados: 81 participantes eran obesos (50,8%), 33 hombres y 48 mujeres. La edad media de los obesos fue de 80,32 (9,23) años. Un 62,2% tenía diagnosticado algún tipo de cardiopatía, siendo: 29,2% cardiopatía isquémica; 46,6% arritmias cardiacas y 20,5% valvulopatías. El IMC, como variable continua, se asoció de forma significativa con la mortalidad (p < 0,001), la edad (0,002), la enfermedad isquémica (0,001), sexo (0,004), hipertensión (0,002), diabetes (0,003) y dislipemia (0,004). También se vio relación directamente proporcional del IMC con el uso de tratamientos con digoxina, diuréticos de asa y espironolactona. EL IMC también se asoció con el número de ingresos, mayor número de enfermedades crónicas concomitantes y mortalidad. Los pacientes con obesidad obtuvieron peores puntuaciones en el cuestionario de calidad de vida MLWHFQ.Conclusiones: El IMC mostró asociación con la mortalidad, la enfermedad isquémica, el sexo, la hipertensión, diabetes y dislipemia en pacientes con insuficiencia cardiaca.
43
Bouzid, Y., H. Siguerdidjane, M. Zareb, and Y. Bestaoui. "Improved IMC-Filter Design to IMC-PI Equivalence: Application to Quadrotor." IFAC-PapersOnLine 52, no. 12 (2019): 158–63. http://dx.doi.org/10.1016/j.ifacol.2019.11.190.
Full text
44
Wirda Kahar, Hardinna, A. M. Zetty Akhtar, Siti Rabiatull Aisha Idris, and Mahadzir Ishak. "Effect of Cooling and Isothermal Aging on Microstructure Using Electroless Nickel (Boron) Plating." Applied Mechanics and Materials 695 (November 2014): 352–56. http://dx.doi.org/10.4028/www.scientific.net/amm.695.352.
Full textAbstract:
This paper presents a study on relationship of cooling rates towards the intermetallic compound (IMC) morphology. Cooling rate is an important parameter as it has significant effect towards the IMC microstructure formation that indirectly affects solders joint reliability. However, there is still insufficient study regarding the effect of cooling rate on the IMC thickness and microstructure behavior by using Nickel Boron as surface finish material in the electronic packaging industry. In this study, Sn-3Ag-0.5Cu solder was used on Nickel Boron as coating layer. Cooling rates were obtained by cooling specimens in different media which is water and air. The elemental composition was confirmed using Energy-dispersive X-ray spectroscopy and the microstructure of each IMC then analyzed using optical microscope, image analyzer and ImageJ. In this study, faster cooling rate (water) found to provide thicker IMC (6μm) compared to the other medium used. The morphology shape of each IMC also differs between different medium of cooling. IMC that undergoes faster cooling showed continues like layer while the one using air cooling formed scallop like IMC.
45
Cheng, Cong-qian, Jie Zhao, and Yang Xu. "Kinetics of intermetallic compound layers and Cu dissolution at Sn1.5Cu/Cu interface under high magnetic field." Journal of Materials Research 25, no. 2 (February 2010): 359–67. http://dx.doi.org/10.1557/jmr.2010.0055.
Full textAbstract:
The kinetics of intermetallic compound (IMC) layer and Cu dissolution at Sn1.5Cu/Cu interface under high magnetic field was experimentally examined. It is found that the IMC layer growth is controlled by flux-driven ripening process. The high magnetic field promotes the growth of IMC layer, retards the dissolution of Cu substrate, and decreases the content of Cu solute at the liquid–IMC interface front. Based on the experimental results, it is considered that the magnetization induced by magnetic field promotes the ripening process for IMC layer growth. The Lorentz force dampening the convection and magnetization decreasing the Cu solubility limit can retard the Cu dissolution and change the solute distribution at the liquid–IMC interface front.
46
Matos Imbert, Ángela M., Jairo Blanco Jiménez, Xiomara Rodríguez, Carina De La Mota, Alina Fernández Genao, Noemí Acevedo Rodríguez, Haydee Rochits Cueto, Joan M. Reynoso Rosario, Michelle M. Jiménez Azcona, and Isi Y. Ortiz Hernandez. "Índice cintura-talla e índice de masa corporal como predictores de riesgo cardiometabólico en niños y adolescentes." Ciencia y Salud 5, no. 2 (June 11, 2021): 77–85. http://dx.doi.org/10.22206/cysa.2021.v5i2.pp77-85.
Full textAbstract:
Objetivo: comparar la utilidad del índice cintura-talla y el índice de masa corporal para detectar factores de riesgo cardiometabólicos en niños de 5-18 años, atendidos en la consulta externa del Hospital Infantil Regional Universitario Doctor Arturo Grullón en el período octubre-diciembre del año 2016.
Método: se realizó un estudio observacional, comparativo, de corte transversal y fuente primaria, con una muestra de 118 pacientes. Se midieron las variables sociodemográficas (edad y sexo), antropométricas (peso, talla, IMC, ICT, PC, TA), y laboratorios (glicemia, ALT, colesterol, triglicéridos, HDL, LDL). Para el análisis cuantitativo se calculó el promedio y la desviación estándar, para el análisis cualitativo se utilizó la prueba estadística chi-cuadrado.
Resultados: tanto el ICT como el IMC detectan de manera similar las alteraciones de la presión arterial sistólica (ICT=15.9 %, IMC=15 %), diastólica (ICT=20.4 %, IMC= 21.8 %), obesidad (ICT=69.5 %, IMC=73.7 %), HDL (ICT=6.8 %, IMC=5.6 %). En relación a la evaluación de la obesidad ambos índices arrojaron resultados afines, 69.5 % para ICT y 73.7 % el IMC. En la valoración de los niveles altos de ALT se obtuvieron resultados similares, presentando el ICT un 8.1 % y el IMC un 8.9 %.
Conclusión: se demostró que tanto el ICT como el IMC son buenos predictores de factores de riesgos cardiometabólicos.
47
Silveira, Erika Aparecida, Gilberto Kac, and Larissa Silva Barbosa. "Prevalência e fatores associados à obesidade em idosos residentes em Pelotas, Rio Grande do Sul, Brasil: classificação da obesidade segundo dois pontos de corte do índice de massa corporal." Cadernos de Saúde Pública 25, no. 7 (July 2009): 1569–77. http://dx.doi.org/10.1590/s0102-311x2009000700015.
Full textAbstract:
Estimar a prevalência e fatores associados à obesidade em idosos segundo dois pontos de corte do índice de massa corporal (IMC). Trata-se de estudo transversal de base populacional em amostra de idosos residentes em Pelotas, Rio Grande do Sul, Brasil. Avaliou-se o estado nutricional, pelo IMC, em 596 idosos, a partir de peso e estatura, referidos e validados. Utilizou-se regressão de Poisson múltipla com análise hierarquizada, com duas variáveis dependentes para definição da obesidade: IMC > 27kg/m² e IMC > 30kg/m², proposta de Lipschitz e da Organização Mundial da Saúde, respectivamente. A prevalência de obesidade foi 48,7% (IC95%: 44,6-52,7) para IMC > 27kg/m² e de 25,3% (IC95%: 21,9-29,0) para IMC > 30kg/m². Observou-se, nos dois modelos de regressão múltipla, associação da obesidade com sexo feminino e idade. Para o IMC > 27kg/m², observou-se associação com idade e tabagismo e, para o desfecho IMC > 30kg/m², com não prática de exercício físico. A prevalência de obesidade nos idosos foi elevada. Sugere-se, sob a ótica da saúde pública, a adoção de um ponto de corte de obesidade mais sensível, ou seja, IMC > 27kg/m² para a população idosa brasileira.
48
Suresh, Rahul, David J. Barakat, Theresa Barberi, Lei Zheng, Elizabeth Jaffee, Kenneth J. Pienta, and Alan D. Friedman. "NF-κB p50-deficient immature myeloid cell (p50-IMC) adoptive transfer slows the growth of murine prostate and pancreatic ductal carcinoma." Journal for ImmunoTherapy of Cancer 8, no. 1 (January 2020): e000244. http://dx.doi.org/10.1136/jitc-2019-000244.
Full textAbstract:
BackgroundMacrophages and dendritic cells lacking the transcription factor nuclear factor kappa B p50 are skewed toward a proinflammatory phenotype, with increased cytokine expression and enhanced T cell activation; additionally, murine melanoma, fibrosarcoma, colon carcinoma, and glioblastoma grow slower in p50−/−mice. We therefore evaluated the efficacy of p50-negative immature myeloid cells (p50-IMCs) adoptively transferred into tumor-bearing hosts. Immature cells were used to maximize tumor localization, and pretreatment with 5-fluorouracil (5FU) was examined due to its potential to impair marrow production of myeloid cells, to target tumor myeloid cells and to release tumor neoantigens.MethodsWild-type (WT)-IMC or p50-IMC were generated by culturing lineage-negative marrow cells from WT or p50−/−mice in media containing thrombopoietin, stem cell factor and Flt3 ligand for 6 days followed by monocyte colony-stimulating factor for 1 day on ultralow attachment plates. Mice inoculated with Hi-Myc prostate cancer (PCa) cells or K-RasG12Dpancreatic ductal carcinoma (PDC)-luciferase cells received 5FU followed 5 days later by three doses of 107immature myeloid cells (IMC) every 3–4 days.ResultsPCa cells grew slower in p50−/−mice, and absence of host p50 prolonged the survival of mice inoculated orthotopically with PDC cells. IMC from Cytomegalovirus (CMV)-luciferase mice localized to tumor, nodes, spleen, marrow, and lung. 5FU followed by p50-IMC slowed PCa and PDC tumor growth, ~3-fold on average, in contrast to 5FU followed by WT-IMC, 5FU alone or p50-IMC alone. Slowed tumor growth was evident for 93% of PCa but only 53% of PDC tumors; we therefore focused on PCa for additional IMC analyses. In PCa, p50-IMC matured into F4/80+macrophages, as well as CD11b+F4/80−CD11c+conventional dendritic cells (cDCs). In both tumor and draining lymph nodes, p50-IMC generated more macrophages and cDCs than WT-IMC. Activated tumor CD8+T cells were increased fivefold by p50-IMC compared with WT-IMC, and antibody-mediated CD8+T cell depletion obviated slower tumor growth induced by 5FU followed by p50-IMC.Conclusions5FU followed by p50-IMC slows the growth of murine prostate and pancreatic carcinoma and depends on CD8+T cell activation. Deletion of p50 in patient-derived marrow CD34+cells and subsequent production of IMC for adoptive transfer may contribute to the therapy of these and additional cancers.
49
TKOTZ, ALEXANDER, JAN CHRISTOPH MUNCK, and ANDREAS ERICH WALD. "INNOVATION MANAGEMENT CONTROL: BIBLIOMETRIC ANALYSIS OF ITS EMERGENCE AND EVOLUTION AS A RESEARCH FIELD." International Journal of Innovation Management 22, no. 03 (March 29, 2018): 1850031. http://dx.doi.org/10.1142/s1363919618500317.
Full textAbstract:
Innovation Management Control (IMC) supports innovation management with valuable information, thus improving innovation effectiveness and efficiency. Literature has shown that different elements of a management control system must be interdependent and that its design must form a coherent system of controls that spans the entire process under control. Accordingly, IMC covers the entire innovation process. However, IMC literature is spread over numerous journals from different disciplines, which may prevent the development of holistic IMC systems. We present a bibliometric analysis that provides insights into the development of IMC as a research field and examines the severity of knowledge dispersal. We build on a database covering 549 papers. The aim of the study is to reveal IMCs emergence and evolution as a research field, and future research directions. Our study shows that IMC combines several subfields and that dispersion is present in IMC, thus slowing knowledge transfer and hindering rapid progress.
50
Wu, Lingling, Yuriy Danko, Fuli Chen, Xuefeng Yao, and Fenghe Zhang. "Mapping the literature of integrated marketing communications: A scientometric analysis using CiteSpace." Innovative Marketing 18, no. 1 (March 9, 2022): 152–67. http://dx.doi.org/10.21511/im.18(1).2022.13.
Full textAbstract:
Integrated marketing communication (IMC) is an effective marketing practice in the age of social media. IMC builds customer relationships and enhances brand value by integrating information from multiple channels and strengthening user interaction. The purpose of this study is to present the development process, current hotspots, and future trends of IMC research. Moreover, it explores the characteristics and patterns of IMC research. First, this paper shows the annual literature volume, leading countries, journals, and authors in IMC research through bibliometrics. Then, five hot research topics are identified through keyword co-occurrence analysis, namely IMC theory and models, brand communication, media research, customer research, and marketing strategy. From 1991 to 2020, IMC research is divided into five phases, each of which is related to the enhancement of user interaction. Future IMC research will continue to be user-centered, and IMC research will continue with social media and branding, as well as research on other topics that can further enhance user interactions. This paper also finds that the characteristics of the concept of IMC itself lead to a constant renewal of its connotations, which is one of the reasons why scholars cannot reach a consensus on the concept of IMC. AcknowledgmentsWe thank Associate Professor Zhenkun Cui of Henan Institute of Science and Technology for his valuable comments during the writing and revision of this paper. The following research projects supported this study: (1) Henan Provincial University Humanities and Social Sciences Research Project No.2022-ZDJH-0099; (2) Henan Provincial University Humanities and Social Sciences Research Project No.2022-ZZJH-158; (3) Henan Province Social Science Planning Project No. 2021BZZ004; and (4) Xinxiang Social Science Federation Research Project No. 2021-167.