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1

Lewis, Jason S., and Kayvan R. Keshari, eds. Imaging and Metabolism. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-61401-4.

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2

van der Wall, E. E., ed. Noninvasive Imaging of Cardiac Metabolism. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3287-6.

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3

W, Weissman Barbara N., ed. Imaging of arthritis and metabolic bone disease. Philadelphia, PA: Mosby/Elsevier, 2009.

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4

European Association of Nuclear Medicine, ed. Radionuclide metabolic therapy: Clinical aspects, dosimetry and imaging. Vienna: European Association of Nuclear Medicine, 2013.

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5

Dirnagl, Ulrich, Arno Villringer, and Karl M. Einhäupl, eds. Optical Imaging of Brain Function and Metabolism. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2468-1.

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6

Ulrich, Dirnagl, Villringer Arno, Einhäupl Karl, and Symposium on Optical Imaging of Brain Function and Metabolism (1991 : Garmisch-Partenkirchen, Germany), eds. Optical imaging of brain function and metabolism. New York: Plenum Press, 1993.

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7

Optical Imaging of Brain Function andMetabolism (Conference) (1991 Garmisch-Partenkirchen, Germany). Optical imaging of brain function and metabolism. New York: Plenum, 1993.

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8

B, Bassingthwaighte James, and McMillin-Wood Jeanie B, eds. Cardiovascular metabolic imaging: Physiologic and biochemical dynamics in vivo. Dallas: American Heart Association, 1985.

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9

Villringer, Arno, and Ulrich Dirnagl, eds. Optical Imaging of Brain Function and Metabolism 2. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4899-0056-2.

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10

Handbook of syndromes and metabolic disorders: Radiologic and clinical manifestations. St. Louis: Mosby, 1998.

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11

J, Roberts Bernard, ed. Notes on prosthetic dentistry. London: Wright, 1989.

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12

C, Stevenson John, ed. New techniques in metabolic bone disease. London: Wright, 1990.

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13

1919-, Taybi Hooshang, ed. Taybi and Lachman's radiology of syndromes, metabolic disorders, and skeletal dysplasias. 5th ed. Philadelphia: Mosby Elsevier, 2007.

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14

S, Sideman, Beyar Rafael, and Henry Goldberg Workshop on Imaging, Measurement, and Analysis of the Heart (6th : 1989 : Elat, Israel), eds. Imaging, measurements, and analysis of the heart. New York: Hemisphere Pub. Corp., 1991.

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15

Nadjmi, Maschallah, ed. Imaging of Brain Metabolism Spine and Cord Interventional Neuroradiology Free Communications. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74337-5.

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16

Gonzalez-Lima, F., Th Finkenstädt, and H. Scheich, eds. Advances in Metabolic Mapping Techniques for Brain Imaging of Behavioral and Learning Functions. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2712-7.

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17

Altoé, Mirella Lorrainy. Diffuse Optical Tomography Imaging of Chemotherapy-Induced Changes in Breast Tissue Metabolism. [New York, N.Y.?]: [publisher not identified], 2020.

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18

-L, Martinot J., Wiesel F. -A, and Ågren H, eds. Studies of brain metabolism in psychiatric patients: Can standards be drawn? Wien: Springer-Verlag, 1992.

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19

T, Moroji, and Yamamoto K, eds. The biology of schizophrenia: Proceedings of the 7th International Symposium of the Tokyo Institute of Psychiatry, Tokyo, Japan, October 19-20, 1992. Amsterdam: Elsevier, 1994.

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20

1948-, Müller Nestor Luiz, Franquet Tomás, Lee Kyung Soo MD, and Silva C. Isabela S, eds. Imaging of pulmonary infections. Philadelphia: Lippincott Williams & Wilkins, 2007.

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21

R, Schelbert Heinrich, and Clinical Cardiology International Symposium on Regional Myocardial Metabolism by Positron Tomography (1984 : Santa Barbara, Calif.), eds. Regional myocardial metabolism by positron tomography. Mahwah, N.J: Foundation for Advances in Clinical Medicine, 1987.

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22

der, Wall E. van, ed. Noninvasive imaging of cardiac metabolism: Single photonscintigraphy, positron emission tomography, and nuclear magnetic resonance. Dordrecht: M. Nijhoff, 1987.

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23

Kazuo, Uemura, ed. Quantification of brain function: Tracer kinetics and image analysis in brain PET : proceedings of PET '93 Akita : Quantification of Brain Function, Akita, Japan, 29-31 May, 1993. Amsterdam: Excerpta Medica, 1993.

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24

Gerhard, Litscher, and Schwarz Gerhard, eds. Transcranial cerebral oximetry. Lengerich: Pabst Science, 1997.

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25

Samir, Zakhari, Witt Ellen, and National Institute on Alcohol Abuse and Alcoholism (U.S.), eds. Imaging in alcohol research: Proceedings of a workshop on imaging in alcohol research, May 9-11, 1991, Wild Dunes, South Carolina. Rockville, MD (5600 Fishers Lane, Rockville 20857): The Institute, 1992.

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26

G, Shulman R., and Rothman D. L, eds. Brain energetics and neuronal activity: Applications to fMRI and medicine. Chichester: Wiley, 2004.

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27

1946-, Miller Richard K., Thiede Henry A, and Rochester Trophoblast Conference. (11th : 1988 : Rochester, N.Y.), eds. Molecular biology and cell regulation of the placenta. Rochester, N.Y: Verav Medical Publishers, 1991.

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28

1935-, Lachman Ralph S., ed. Radiology of syndromes, metabolic disorders, and skeletal dysplasias. 4th ed. St. Louis: Mosby, 1996.

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29

1935-, Lachman Ralph S., and Taybi Hooshang 1919-, eds. Radiology of syndromes, metabolic disorders, and skeletal dysplasias. 3rd ed. Chicago: Year Book Medical Publishers, 1990.

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30

R, Bergmann Steven, and Sobel Burton E, eds. Positron emission tomography of the heart. Mt. Kisco, NY: Futura Pub., 1992.

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31

1963-, Buzug Thorsten M., and ebrary Inc, eds. Magnetic nanoparticles: Particle science, imaging technology, and clinical applications : proceedings of the First International Workshop on Magnetic Particle Imaging, Institute of Medical Engineering, University of Lübeck, Germany, 18 - 19 March 2010. Singapore: World Scientific Pub. Co., 2010.

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32

Gropler, Robert J. Imaging of Myocardial Metabolism. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0025.

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Abnormalities in myocardial substrate metabolism play a key role in the pathogenesis of a host of cardiac disease processes. The importance is highlighted by the routine clinical use of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) to measure myocardial glucose metabolism to detect viable tissue in patients with ischemic cardiomyopathy and the development of novel therapies designed to modulate myocardial metabolism. Our understanding of myocardial metabolism has benefitted from the application of advanced molecular biologic techniques and the development of elegant genetic models to of myocardial metabolic disease resulting in a greater appreciation for the pleiotropic actions of cellular metabolism. In parallel, there have been significant advances in radionuclide-based metabolic imaging techniques in terms instrumentation design, radiopharmaceutical development and small animal imaging. These advances have further ensconced radionuclide metabolic imaging techniques as tools to further our understanding of various forms of cardiovascular disease and potentially improve the care of the cardiac patient. In this chapter several of key advances in metabolic imaging will be described, their potential new clinical applications are reviewed and contribution to cardiovascular research highlighted.
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33

Lewis, Jason S., and Kayvan R. Keshari. Imaging and Metabolism. Springer, 2017.

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34

Lewis, Jason S., and Kayvan R. Keshari. Imaging and Metabolism. Springer, 2018.

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35

Imaging in Endocrinology. Wiley-Blackwell, 2014.

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36

Pozzilli, Paolo, Andrea Lenzi, Bart L. Clarke, and Young William F. Jr. Imaging in Endocrinology. Wiley & Sons, Limited, John, 2014.

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37

Pozzilli, Paolo, Andrea Lenzi, Bart L. Clarke, and Young William F. Jr. Imaging in Endocrinology. Wiley & Sons, Incorporated, John, 2013.

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38

Pozzilli, Paolo, Andrea Lenzi, Bart L. Clarke, and Young William F. Jr. Imaging in Endocrinology. Wiley & Sons, Incorporated, John, 2013.

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39

Somatostatin Receptor Imaging (Hormone & Metabolic Research). Thieme Publishing Group, 1993.

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40

Bashir, Adil. Cardiac Metabolic Imaging: In Vivo Approaches. Elsevier Science & Technology Books, 2021.

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41

Imaging of Arthritis and Metabolic Bone Disease. Elsevier, 2009. http://dx.doi.org/10.1016/b978-0-323-04177-5.x0001-8.

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42

Podo, Franca, Zaver M. Bhujwalla, and Egidio Iorio, eds. Exploring Cancer Metabolic Reprogramming Through Molecular Imaging. Frontiers Media SA, 2017. http://dx.doi.org/10.3389/978-2-88945-234-7.

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43

Pope, Whitney B. Glioma Imaging: Physiologic, Metabolic, and Molecular Approaches. Springer International Publishing AG, 2020.

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44

Pope, Whitney B. Glioma Imaging: Physiologic, Metabolic, and Molecular Approaches. Springer, 2019.

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45

Pozzilli, Paolo, Andrea Lenzi, Bart L. Clarke, and William F. Jr Young. Imaging in Endocrinology. Wiley & Sons, Incorporated, John, 2013.

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46

Narayana, Shalini, Babak Saboury, Andrew B. Newberg, Andrew C. Papanicolaou, and Abass Alavi. Positron Emission Tomography. Edited by Andrew C. Papanicolaou. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199764228.013.8.

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Positron emission tomography (PET) is an imaging method that utilizes compounds labeled with positron-emitting radioisotopes as molecular probes to evaluate different neurophysiological processes quantitatively and noninvasively. This chapter provides a background regarding positron emission, radiotracer chemistry, and detector and scanner instrumentation, as well as analytical methods for evaluating basic brain physiology, such as cerebral blood flow and oxygen and glucose metabolism. The methodological aspects of PET imaging, such as patient preparation and optimal scanning parameters, are discussed. Examples of application of blood flow and metabolic imaging in both research and clinical scenarios for the evaluation of normal neurophysiology are provided. Recent advances in PET imaging, including PET-CT and PET-MRI, are also described. Finally, the unique strengths of PET imaging are highlighted.
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47

Einhäupl, K. M., Ulrich Dirnagl, and Arno Villringer. Optical Imaging of Brain Function and Metabolism. Springer London, Limited, 2013.

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48

Dirnagl, Ulrich, Arno Villringer, and K. M. Einhäupl. Optical Imaging of Brain Function and Metabolism. Springer, 2013.

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49

Chawla, Sanjeev, Manoj Kumar, and Ravi Prakash Reddy Nanga, eds. Structural, Metabolic and Physiologic MR Imaging to Study Glioblastomas. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88974-968-3.

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50

Dendale, Paul A. Perfusion, function, and metabolism after acute myocardial infarction. University of Leiden], 1998.

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