Academic literature on the topic 'Image segmentatio'

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Journal articles on the topic "Image segmentatio"

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Pitkänen, Johanna, Juha Koikkalainen, Tuomas Nieminen, Ivan Marinkovic, Sami Curtze, Gerli Sibolt, Hanna Jokinen, et al. "Evaluating severity of white matter lesions from computed tomography images with convolutional neural network." Neuroradiology 62, no. 10 (April 13, 2020): 1257–63. http://dx.doi.org/10.1007/s00234-020-02410-2.

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Abstract Purpose Severity of white matter lesion (WML) is typically evaluated on magnetic resonance images (MRI), yet the more accessible, faster, and less expensive method is computed tomography (CT). Our objective was to study whether WML can be automatically segmented from CT images using a convolutional neural network (CNN). The second aim was to compare CT segmentation with MRI segmentation. Methods The brain images from the Helsinki University Hospital clinical image archive were systematically screened to make CT-MRI image pairs. Selection criteria for the study were that both CT and MRI images were acquired within 6 weeks. In total, 147 image pairs were included. We used CNN to segment WML from CT images. Training and testing of CNN for CT was performed using 10-fold cross-validation, and the segmentation results were compared with the corresponding segmentations from MRI. Results A Pearson correlation of 0.94 was obtained between the automatic WML volumes of MRI and CT segmentations. The average Dice similarity index validating the overlap between CT and FLAIR segmentations was 0.68 for the Fazekas 3 group. Conclusion CNN-based segmentation of CT images may provide a means to evaluate the severity of WML and establish a link between CT WML patterns and the current standard MRI-based visual rating scale.
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Yazdi, Mahsa Badiee, Mohammad Mahdi Khalilzadeh, and Mohsen Foroughipour. "MRI SEGMENTATION BY FUZZY CLUSTERING METHOD BASED ON PRIOR KNOWLEDGE." Biomedical Engineering: Applications, Basis and Communications 28, no. 04 (August 2016): 1650025. http://dx.doi.org/10.4015/s1016237216500253.

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Image segmentation is often required as a fundamental stage in medical image processing, particularly during the clinical analysis of magnetic resonance (MR) brain images. Fuzzy c-means (FCM) clustering algorithm is one of the best known and widely used segmentation methods, but this algorithm has some problem for segmenting simulated MRI images to high number of clusters with different noise levels and real images because of spatial complexities. Anatomical segmentation usually requires information derived from the manual segmentations done by experts, prior knowledge can be useful to modify image segmentation methods. In this paper, we propose some methods to modify FCM algorithm using expert manual segmentation as prior knowledge. We developed combination of FCM algorithm and prior knowledge in three ways, in order to improve segmentation of brain MR images with high noise level and spatial complexity. In real images, we had a considerable improvement in similarity index of three classes (white matter, gray matter, CSF) and in simulated images with different noise levels evaluation criteria of white matter and gray matter has improved.
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Wang, Guodong, Jie Xu, Qian Dong, and Zhenkuan Pan. "Active Contour Model Coupling with Higher Order Diffusion for Medical Image Segmentation." International Journal of Biomedical Imaging 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/237648.

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Active contour models are very popular in image segmentation. Different features such as mean gray and variance are selected for different purpose. But for image with intensity inhomogeneities, there are no features for segmentation using the active contour model. The images with intensity inhomogeneities often occurred in real world especially in medical images. To deal with the difficulties raised in image segmentation with intensity inhomogeneities, a new active contour model with higher-order diffusion method is proposed. With the addition of gradient and Laplace information, the active contour model can converge to the edge of the image even with the intensity inhomogeneities. Because of the introduction of Laplace information, the difference scheme becomes more difficult. To enhance the efficiency of the segmentation, the fast Split Bregman algorithm is designed for the segmentation implementation. The performance of our method is demonstrated through numerical experiments of some medical image segmentations with intensity inhomogeneities.
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Weishaupt, L. L., T. Vuong, A. Thibodeau-Antonacci, A. Garant, K. S. Singh, C. Miller, A. Martin, and S. Enger. "A121 QUANTIFYING INTER-OBSERVER VARIABILITY IN THE SEGMENTATION OF RECTAL TUMORS IN ENDOSCOPY IMAGES AND ITS EFFECTS ON DEEP LEARNING." Journal of the Canadian Association of Gastroenterology 5, Supplement_1 (February 21, 2022): 140–42. http://dx.doi.org/10.1093/jcag/gwab049.120.

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Abstract Background Tumor delineation in endoscopy images is a crucial part of clinical diagnoses and treatment planning for rectal cancer patients. However, it is challenging to detect and adequately determine the size of tumors in these images, especially for inexperienced clinicians. This motivates the need for a standardized, automated segmentation method. While deep learning has proven to be a powerful tool for medical image segmentation, it requires a large quantity of high-quality annotated training data. Since the annotation of endoscopy images is prone to high inter-observer variability, creating a robust unbiased deep learning model for this task is challenging. Aims To quantify the inter-observer variability in the manual segmentation of tumors in endoscopy images of rectal cancer patients and investigate an automated approach using deep learning. Methods Three gastrointestinal physicians and radiation oncologists (G1, G2, and G3) segmented 2833 endoscopy images into tumor and non-tumor regions. The whole image classifications and the pixelwise classifications into tumor and non-tumor were compared to quantify the inter-observer variability. Each manual annotator is from a different institution. Three different deep learning architectures (FCN32, U-Net, and SegNet) were trained on the binary contours created by G2. This naive approach investigates the effectiveness of neglecting any information about the uncertainty associated with the task of tumor delineation. Finally, segmentations from G2 and the deep learning models’ predictions were compared against ground truth labels from G1 and G3, and accuracy, sensitivity, specificity, precision, and F1 scores were computed for images where both segmentations contained tumors. Results The deep-learning segmentation took less than 1 second, while manual segmentation took approximately 10 seconds per image. There was significant inter-observer variability for the whole-image classifications made by the manual annotators (Figure 1A). The segmentation scores achieved by the deep learning models (SegNet F1:0.80±0.08) were comparable to the inter-observer variability for the pixel-wise image classification (Figure 1B). Conclusions The large inter-observer variability observed in this study indicates a need for an automated segmentation tool for tumors in endoscopy images of rectal cancer patients. While deep learning models trained on a single observer’s labels can segment tumors with an accuracy similar to the inter-observer variability, these models do not accurately reflect the intrinsic uncertainty associated with tumor delineation. In our ongoing studies, we investigate training a model with all observers’ contours to reflect the uncertainty associated with the tumor segmentations. Funding Agencies CIHRNSERC
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Conti, Luis Américo, and Murilo Baptista. "SYNTHETIC APERTURE SONAR IMAGES SEGMENTATION USING DYNAMICAL MODELING ANALYSIS." Revista Brasileira de Geofísica 31, no. 3 (September 1, 2013): 455. http://dx.doi.org/10.22564/rbgf.v31i3.315.

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ABSTRACT. Symbolic Models applied to Synthetic Aperture Sonar images are proposed in order to assess the validity and reliability of use of such models and evaluate how effective they can be in terms of image classification and segmentation. We developed an approach for the description of sonar images where the pixels distribution can be transformed into points in the symbolic space in a similar way as symbolic space can encode a trajectory of a dynamical system. One of the main characteristic of approach is that points in the symbolic space are mapped respecting dynamical rules and, as a consequence, it can possible to calculate quantities thatcharacterize the dynamical system, such as Fractal Dimension (D), Shannon Entropy (H) and the amount of information of the image. It also showed potential to classify image sub-patterns based on the textural characteristics of the seabed. The proposed method reached a reasonable degree of success with results compatible with the classical techniques described in literature.Keywords: Synthetic Aperture Sonar, image processing, dynamical models, fractal, seabed segmentation. RESUMO. Este estudo apresenta uma proposta de metodologia para segmentação e classificação de imagens de sonar de Abertura Sintética a partir de modelos de Dinâmica Simbólica. Foram desenvolvidas, em um primeiro momento, técnicas de descrição de registros de sonar, com base na transformação da distribuição dos pixels da imagem em pontos em um espaço simbólico, codificado a partir de uma função de interação, de modo que as imagens podem ser interpretadas como sistemas dinâmicos em que trajetórias do sistema podem ser estabelecidas. Uma das características marcantes deste método é que, ao descrever uma imagem como um sistema dinâmico, é possível calcular grandezas como dimensão fractal (D) e entropia de Shannon (H) além da quantidade de informação inerente a imagem. Foi possível classificar, posteriormente, características texturais das imagens com base nas propriedades dinâmicas do espaço simbólico, o que permitiu a segmentação automática de padrões de “backscatter” indicando variações da geologia/geomorfologia do substrato marinho. O método proposto atingiu um razoável grau de sucesso em relação à acurácia de segmentação, com sucesso compatível com métodos alternativos descritos em literatura.Palavras-chave: sonar de abertura sintética, processamento de imagens, modelos dinâmicos, fractal, segmentação.
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Yao, Hongtai, Xianpei Wang, Le Zhao, Meng Tian, Zini Jian, Li Gong, and Bowen Li. "An Object-Based Markov Random Field with Partition-Global Alternately Updated for Semantic Segmentation of High Spatial Resolution Remote Sensing Image." Remote Sensing 14, no. 1 (December 29, 2021): 127. http://dx.doi.org/10.3390/rs14010127.

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The Markov random field (MRF) method is widely used in remote sensing image semantic segmentation because of its excellent spatial (relationship description) ability. However, there are some targets that are relatively small and sparsely distributed in the entire image, which makes it easy to misclassify these pixels into different classes. To solve this problem, this paper proposes an object-based Markov random field method with partition-global alternately updated (OMRF-PGAU). First, four partition images are constructed based on the original image, they overlap with each other and can be reconstructed into the original image; the number of categories and region granularity for these partition images are set. Then, the MRF model is built on the partition images and the original image, their segmentations are alternately updated. The update path adopts a circular path, and the correlation assumption is adopted to establish the connection between the label fields of partition images and the original image. Finally, the relationship between each label field is constantly updated, and the final segmentation result is output after the segmentation has converged. Experiments on texture images and different remote sensing image datasets show that the proposed OMRF-PGAU algorithm has a better segmentation performance than other selected state-of-the-art MRF-based methods.
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Lubis, Kesuma Anggraini, Muhammad Rusdi, and Sugianto Sugianto. "Proses Segmentasi Citra Satelit Untuk Pemetaan Tutupan Lahan." Jurnal Ilmiah Mahasiswa Pertanian 6, no. 4 (November 1, 2021): 691–98. http://dx.doi.org/10.17969/jimfp.v6i4.18414.

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Abstrak. Salah satu permasalahan penting dalam bidang pengolahan citra dan pengenalan pola adalah segmentasi citra ke dalam area homogen. Ekstraksi ciri dan segmentasi citra merupakan langkah awal dalam analisis citra. Tujuan utama segmentasi adalah membagi citra ke dalam bagian-bagian yang mempunyai korelasi kuat dengan objek dalam citra. Pada proses segmentasi dapat dilakukan dengan berbagai pendekatan algoritma, salah satu algoritma yang banyak digunakan pada penelitian-penelitian sebelumnya adalah algoritma multiresolusi segmentasi. Berdasarkan konsep segmentasi, untuk mendapatkan hasil segmentasi dengan menggunakan algoritma multiresolusi segmentasi tergantung dari lima parameter yaitu parameter skala, bentuk, warna, kehalusan dan kekompakan. Penelitian ini bertujuan untuk mengkaji proses metode segmentasi citra satelit untuk pemetaan tutupan lahan dengan menggunakan algoritma multiresolution segmentation.Satellite Image Segmentation Process for Land Cover MappingAbstract. One of the important problems in image processing and pattern recognition is image segmentation into homogeneous areas. Feature extraction and image segmentation are the first steps in image analysis. The main purpose of segmentation is to divide the image into parts that have a strong correlation with the objects in the image. The segmentation process can be done with various algorithm approaches, one of the algorithms that is widely used in previous studies is the multi-resolution segmentation algorithm. Based on the concept of segmentation, to obtain segmentation results using a multi-resolution segmentation algorithm depends on five parameters, namely the parameters of scale, shape, color, smoothness and compactness. This study aims to examine the process of satellite image segmentation method for land cover mapping using a multiresolution segmentation algorithm.
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Li, Yuan, Fu Cang Jia, Xiao Dong Zhang, Cheng Huang, and Huo Ling Luo. "Local Patch Similarity Ranked Voxelwise STAPLE on Magnetic Resonance Image Hippocampus Segmentation." Applied Mechanics and Materials 333-335 (July 2013): 1065–70. http://dx.doi.org/10.4028/www.scientific.net/amm.333-335.1065.

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The segmentation and labeling of sub-cortical structures of interest are important tasks for the assessment of morphometric features in quantitative magnetic resonance (MR) image analysis. Recently, multi-atlas segmentation methods with statistical fusion strategy have demonstrated high accuracy in hippocampus segmentation. While, most of the segmentations rarely consider spatially variant model and reserve all segmentations. In this study, we propose a novel local patch-based and ranking strategy for voxelwise atlas selection to extend the original Simultaneous Truth and Performance Level Estimation (STAPLE) algorithm. The local ranking strategy is based on the metric of normalized cross correlation (NCC). Unlike its predecessors, this method estimates the fusion of each voxel patch-by-patch and makes use of gray image features as a prior. Validation results on 33 pairs of hippocampus MR images show good performance on the segmentation of hippocampus.
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Cruz-Aceves, I., J. G. Avina-Cervantes, J. M. Lopez-Hernandez, M. G. Garcia-Hernandez, M. Torres-Cisneros, H. J. Estrada-Garcia, and A. Hernandez-Aguirre. "Automatic Image Segmentation Using Active Contours with Univariate Marginal Distribution." Mathematical Problems in Engineering 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/419018.

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This paper presents a novel automatic image segmentation method based on the theory of active contour models and estimation of distribution algorithms. The proposed method uses the univariate marginal distribution model to infer statistical dependencies between the control points on different active contours. These contours have been generated through an alignment process of reference shape priors, in order to increase the exploration and exploitation capabilities regarding different interactive segmentation techniques. This proposed method is applied in the segmentation of the hollow core in microscopic images of photonic crystal fibers and it is also used to segment the human heart and ventricular areas from datasets of computed tomography and magnetic resonance images, respectively. Moreover, to evaluate the performance of the medical image segmentations compared to regions outlined by experts, a set of similarity measures has been adopted. The experimental results suggest that the proposed image segmentation method outperforms the traditional active contour model and the interactive Tseng method in terms of segmentation accuracy and stability.
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Beasley, Ryan A. "Semiautonomous Medical Image Segmentation Using Seeded Cellular Automaton Plus Edge Detector." ISRN Signal Processing 2012 (May 17, 2012): 1–9. http://dx.doi.org/10.5402/2012/914232.

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Segmentations of medical images are required in a number of medical applications such as quantitative analyses and patient-specific orthotics, yet accurate segmentation without significant user attention remains a challenge. This work presents a novel segmentation algorithm combining the region-growing Seeded Cellular Automata with a boundary term based on an edge-detected image. Both single processor and parallel processor implementations are developed and the algorithm is shown to be suitable for quick segmentations (2.2 s for voxel brain MRI) and interactive supervision (2–220 Hz). Furthermore, a method is described for generating appropriate edge-detected images without requiring additional user attention. Experiments demonstrate higher segmentation accuracy for the proposed algorithm compared with both Graphcut and Seeded Cellular Automata, particularly when provided minimal user attention.
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Dissertations / Theses on the topic "Image segmentatio"

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Zeng, Ziming. "Medical image segmentation on multimodality images." Thesis, Aberystwyth University, 2013. http://hdl.handle.net/2160/17cd13c2-067c-451b-8217-70947f89164e.

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Segmentation is a hot issue in the domain of medical image analysis. It has a wide range of applications on medical research. A great many medical image segmentation algorithms have been proposed, and many good segmentation results were obtained. However, due to the noise, density inhomogenity, partial volume effects, and density overlap between normal and abnormal tissues in medical images, the segmentation accuracy and robustness of some state-of-the-art methods still have room for improvement. This thesis aims to deal with the above segmentation problems and improve the segmentation accuracy. This project investigated medical image segmentation methods across a range of modalities and clinical applications, covering magnetic resonance imaging (MRI) in brain tissue segmentation, MRI based multiple sclerosis (MS) lesions segmentation, histology based cell nuclei segmentation, and positron emission tomography (PET) based tumour detection. For the brain MRI tissue segmentation, a method based on mutual information was developed to estimate the number of brain tissue groups. Then a unsupervised segmentation method was proposed to segment the brain tissues. For the MS lesions segmentation, 2D/3D joint histogram modelling were proposed to model the grey level distribution of MS lesions in multimodality MRI. For the PET segmentation of the head and neck tumours, two hierarchical methods based on improved active contour/surface modelling were proposed to segment the tumours in PET volumes. For the histology based cell nuclei segmentation, a novel unsupervised segmentation based on adaptive active contour modelling driven by morphology initialization was proposed to segment the cell nuclei. Then the segmentation results were further processed for subtypes classification. Among these segmentation approaches, a number of techniques (such as modified bias field fuzzy c-means clustering, multiimage spatially joint histogram representation, and convex optimisation of deformable model, etc.) were developed to deal with the key problems in medical image segmentation. Experiments show that the novel methods in this thesis have great potential for various image segmentation scenarios and can obtain more accurate and robust segmentation results than some state-of-the-art methods.
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Hillman, Peter. "Segmentation of motion picture images and image sequences." Thesis, University of Edinburgh, 2002. http://hdl.handle.net/1842/15026.

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For Motion Picture Special Effects, it is often necessary to take a source image of an actor, segment the actor from the unwanted background, and then composite over a new background. The resultant image appears as if the actor was filmed in front of the new background. The standard approach requires the unwanted background to be a blue or green screen. While this technique is capable of handling areas where the foreground (the actor) blends into the background, the physical requirements present many practical problems. This thesis investigates the possibility of segmenting images where the unwanted background is more varied. Standard segmentation techniques tend not to be effective, since motion picture images have extremely high resolution and high accuracy is required to make the result appear convincing. A set of novel algorithms which require minimal human interaction to initialise the processing is presented. These algorithms classify each pixel by comparing its colour to that of known background and foreground areas. They are shown to be effective where there is a sufficient distinction between the colours of the foreground and background. A technique for assessing the quality of an image segmentation in order to compare these algorithms to alternative solutions is presented. Results are included which suggest that in most cases the novel algorithms have the best performance, and that they produce results more quickly than the alternative approaches. Techniques for segmentation of moving images sequences are then presented. Results are included which show that only a few frames of the sequence need to be initialised by hand, as it is often possible to generate automatically the input required to initialise processing for the remaining frames. A novel algorithm which can produce acceptable results on image sequences where more conventional approaches fail or are too slow to be of use is presented.
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Torres, Rafael Siqueira. "Segmentação semiautomática de conjuntos completos de imagens do ventrículo esquerdo." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/100/100131/tde-17112017-121645/.

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A área médica tem se beneficiado das ferramentas construídas pela Computação e, ao mesmo tempo, tem impulsionado o desenvolvimento de novas técnicas em diversas especialidades da Computação. Dentre estas técnicas a segmentação tem como objetivo separar em uma imagem objetos de interesse, podendo chamar a atenção do profissional de saúde para áreas de relevância ao diagnóstico. Além disso, os resultados da segmentação podem ser utilizados para a reconstrução de modelos tridimensionais, que podem ter características extraídas que auxiliem o médico em tomadas de decisão. No entanto, a segmentação de imagens médicas ainda é um desafio, por ser extremamente dependente da aplicação e das estruturas de interesse presentes na imagem. Esta dissertação apresenta uma técnica de segmentação semiautomática do endocárdio do ventrículo esquerdo em conjuntos de imagens cardíacas de Ressonância Magnética Nuclear. A principal contribuição é a segmentação considerando todas as imagens provenientes de um exame, por meio da propagação dos resultados obtidos em imagens anteriormente processadas. Os resultados da segmentação são avaliados usando-se métricas objetivas como overlap, entre outras, comparando com imagens fornecidas por especialistas na área de Cardiologia
The medical field has been benefited from the tools built by Computing and has promote the development of new techniques in diverse Computer specialties. Among these techniques, the segmentation aims to divide an image into interest objects, leading the attention of the specialist to areas that are relevant in diagnosys. In addition, segmentation results can be used for the reconstruction of three-dimensional models, which may have extracted features that assist the physician in decision making. However, the segmentation of medical images is still a challenge because it is extremely dependent on the application and structures of interest present in the image. This dissertation presents a semiautomatic segmentation technique of the left ventricular endocardium in sets of cardiac images of Nuclear Magnetic Resonance. The main contribution is the segmentation considering all the images coming from an examination, through the propagation of the results obtained in previously processed images. Segmentation results are evaluated using objective metrics such as overlap, among others, compared to images provided by specialists in the Cardiology field
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Murphy, Sean Daniel. "Medical image segmentation in volumetric CT and MR images." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3816/.

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This portfolio thesis addresses several topics in the field of 3D medical image analysis. Automated methods are used to identify structures and points of interest within the body to aid the radiologist. The automated algorithms presented here incorporate many classical machine learning and imaging techniques, such as image registration, image filtering, supervised classification, unsupervised clustering, morphology and probabilistic modelling. All algorithms are validated against manually collected ground truth. Chapter two presents a novel algorithm for automatically detecting named anatomical landmarks within a CT scan, using a linear registration based atlas framework. The novel scans may contain a wide variety of anatomical regions from throughout the body. Registration is typically posed as a numerical optimisation problem. For this problem the associated search space is shown to be non-convex and so standard registration approaches fail. Specialised numerical optimisation schemes are developed to solve this problem with an emphasis placed on simplicity. A semi-automated algorithm for finding the centrelines of coronary arterial trees in CT angiography scans given a seed point is presented in chapter three. This is a modified classical region growing algorithm whereby the topology and geometry of the tree are discovered as the region grows. The challenges presented by the presence of large organs and other extraneous material in the vicinity of the coronary trees is mitigated by the use of an efficient modified 3D top-hat transform. Chapter four compares the accuracy of three unsupervised clustering algorithms when applied to automated tissue classification within the brain on 3D multi-spectral MR images. Chapter five presents a generalised supervised probabilistic framework for the segmentation of structures/tissues in medical images called a spatially varying classifier (SVC). This algorithm leverages off non-rigid registration techniques and is shown to be a generalisation of atlas based techniques and supervised intensity based classification. This is achieved by constructing a multivariate Gaussian classifier for each voxel in a reference scan. The SVC is applied in the context of tissue classification in multi-spectral MR images in chapter six, by simultaneously extracting the brain and classifying the tissues types within it. A specially designed pre-processing pipeline is presented which involves inter-sequence registration, spatial normalisation and intensity normalisation. The SVC is then applied to the problem of multi-compartment heart segmentation in CT angiography data with minimal modification. The accuracy of this method is shown to be comparable to other state of the art methods in the field.
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Kim, Kyu-Heon. "Segmentation of natural texture images using a robust stochastic image model." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307927.

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Badiei, Sara. "Prostate segmentation in ultrasound images using image warping and ellipsoid fitting." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31737.

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This thesis outlines an algorithm for 2D and 3D semi-automatic segmentation of the prostate from B-mode trans-rectal ultrasound (TRUS) images. In semi-automatic segmentation, a computer algorithm outlines the boundary of the prostate given a few initialization points. The algorithm is designed for prostate brachytherapy and has the potential to: i) replace pre-operative manual segmentation, ii) enable intra-operative segmentation, and iii) be integrated into a visualization tool for training residents. The segmentation algorithm makes use of image warping to make the 2D prostate boundary elliptical. A Star Kalman based edge detector is then guided along the elliptical shape to find the prostate boundary in the TRUS image. A second ellipse is then fit to the edge detected measurement points. Once all 2D slices are segmented in this manner an ellipsoid is fit to the 3D cloud of points. Finally a reverse warping algorithm gives us the segmented prostate volume. In-depth 2D and 3D clinical studies show promising results. In 2D, distance based metrics show a mean absolute difference of 0.67 ± 0.18mm between manual and semi-automatic segmentation and area based metrics show average sensitivity and accuracy over 97% and 93% respectively. In 3D, i) the difference between manual and semi-automatic segmentation is on the order of interobserver variability, ii) the repeatability of the segmentation algorithm is consistently better than the intra-observer variability, and iii) the sensitivity and accuracy are 97% and 85% respectively. The 3D algorithm requires only 5 initialization points and can segment a prostate volume in less than 10 seconds (approximately 40 times faster than manual segmentation). The novelties of this algorithm, in comparison to other works, are in the warping and ellipse/ ellipsoid fitting steps. These two combine to provide a simple solution that works well even with non-ideal images to produce accurate, real-time results.
Applied Science, Faculty of
Electrical and Computer Engineering, Department of
Graduate
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Li, Xiaobing. "Automatic image segmentation based on level set approach: application to brain tumor segmentation in MR images." Reims, 2009. http://theses.univ-reims.fr/exl-doc/GED00001120.pdf.

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L'objectif de la thèse est de développer une segmentation automatique des tumeurs cérébrales à partir de volumes IRM basée sur la technique des « level sets ». Le fonctionnement «automatique» de ce système utilise le fait que le cerveau normal est symétrique et donc la localisation des régions dissymétriques permet d'estimer le contour initial de la tumeur. La première étape concerne le prétraitement qui consiste à corriger l'inhomogénéité de l'intensité du volume IRM et à recaler spatialement les volumes d'IRM d'un même patient à différents instants. Le plan hémisphérique du cerveau est recherché en maximisant le degré de similarité entre la moitié du volume et de sa réflexion. Le contour initial de la tumeur est ainsi extrait à partir de la dissymétrie entre les deux hémisphères. Ce contour initial est évolué et affiné par une technique de « level set » afin de trouver le contour réel de la tumeur. Les critères d'arrêt de l'évolution ont été proposés en fonction des propriétés de la tumeur. Finalement, le contour de la tumeur est projetée sur les images adjacentes pour former les nouveaux contours initiaux. Ce traitement est itéré sur toutes les coupes pour obtenir la segmentation de la tumeur en 3D. Le système ainsi réalisé est utilisé pour suivre un patient pendant toute la période thérapeutique, avec des examens tous les quatre mois, ce qui permet au médecin de contrôler l'état de développement de la tumeur et ainsi d'évaluer l'efficacité du traitement thérapeutique. La méthode a été évaluée quantitativement par la comparaison avec des tracés manuels des experts. De bons résultats sont obtenus sur des images réelles IRM
The aim of this dissertation is to develop an automatic segmentation of brain tumors from MRI volume based on the technique of "level sets". The term "automatic" uses the fact that the normal brain is symmetrical and the localization of asymmetrical regions permits to estimate the initial contour of the tumor. The first step is preprocessing, which is to correct the intensity inhomogeneity of volume MRI and spatially realign the MRI volumes of the same patient at different moments. The plan hemispherical brain is then calculated by maximizing the degree of similarity between the half of the volume and his reflexion. The initial contour of the tumor can be extracted from the asymmetry between the two hemispheres. This initial contour is evolved and refined by the technique "level set" in order to find the real contour of the tumor. The criteria for stopping the evolution have been proposed and based on the properties of the tumor. Finally, the contour of the tumor is projected onto the adjacent images to form the new initial contours. This process is iterated on all slices to obtain the segmentation of the tumor in 3D. The proposed system is used to follow up patients throughout the medical treatment period, with examinations every four months, allowing the physician to monitor the state of development of the tumor and evaluate the effectiveness of the therapy. The method was quantitatively evaluated by comparison with manual tracings experts. Good results are obtained on real MRI images
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Horne, Caspar. "Unsupervised image segmentation /." Lausanne : EPFL, 1991. http://library.epfl.ch/theses/?nr=905.

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Bhalerao, Abhir. "Multiresolution image segmentation." Thesis, University of Warwick, 1991. http://wrap.warwick.ac.uk/60866/.

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Image segmentation is an important area in the general field of image processing and computer vision. It is a fundamental part of the 'low level' aspects of computer vision and has many practical applications such as in medical imaging, industrial automation and satellite imagery. Traditional methods for image segmentation have approached the problem either from localisation in class space using region information, or from localisation in position, using edge or boundary information. More recently, however, attempts have been made to combine both region and boundary information in order to overcome the inherent limitations of using either approach alone. In this thesis, a new approach to image segmentation is presented that integrates region and boundary information within a multiresolution framework. The role of uncertainty is described, which imposes a limit on the simultaneous localisation in both class and position space. It is shown how a multiresolution approach allows the trade-off between position and class resolution and ensures both robustness in noise and efficiency of computation. The segmentation is based on an image model derived from a general class of multiresolution signal models, which incorporates both region and boundary features. A four stage algorithm is described consisting of: generation of a low-pass pyramid, separate region and boundary estimation processes and an integration strategy. Both the region and boundary processes consist of scale-selection, creation of adjacency graphs, and iterative estimation within a general framework of maximum a posteriori (MAP) estimation and decision theory. Parameter estimation is performed in situ, and the decision processes are both flexible and spatially local, thus avoiding assumptions about global homogeneity or size and number of regions which characterise some of the earlier algorithms. A method for robust estimation of edge orientation and position is described which addresses the problem in the form of a multiresolution minimum mean square error (MMSE) estimation. The method effectively uses the spatial consistency of output of small kernel gradient operators from different scales to produce more reliable edge position and orientation and is effective at extracting boundary orientations from data with low signal-to-noise ratios. Segmentation results are presented for a number of synthetic and natural images which show the cooperative method to give accurate segmentations at low signal-to-noise ratios (0 dB) and to be more effective than previous methods at capturing complex region shapes.
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Draelos, Timothy John 1961. "INTERACTIVE IMAGE SEGMENTATION." Thesis, The University of Arizona, 1987. http://hdl.handle.net/10150/276392.

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Books on the topic "Image segmentatio"

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Bhalerao, Abhir H. Multiresolution image segmentation. [s.l.]: typescript, 1991.

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El-Baz, Ayman, Xiaoyi Jiang, and Suri Jasjit, eds. Biomedical Image Segmentation. Taylor & Francis Group, 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742: CRC Press, 2016. http://dx.doi.org/10.4324/9781315372273.

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Roland, Wilson. Image segmentation and uncertainty. Letchworth, Herts., England: Research Studies Press, 1988.

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Morel, Jean Michel, and Sergio Solimini. Variational Methods in Image Segmentation. Boston, MA: Birkhäuser Boston, 1995. http://dx.doi.org/10.1007/978-1-4684-0567-5.

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Köster, Klaus. Robust clustering and image segmentation. Birmingham: University of Birmingham, 1999.

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Siddiqui, Fasahat Ullah, and Abid Yahya. Clustering Techniques for Image Segmentation. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-81230-0.

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Martin, Ian John. Multi-spectral image segmentation and compression. [s.l.]: typescript, 1999.

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Bhanu, Bir. Genetic Learning for Adaptive Image Segmentation. Boston, MA: Springer US, 1994.

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Bhanu, Bir. Genetic learning for adaptive image segmentation. Boston: Kluwer Academic Publishers, 1994.

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Bhanu, Bir, and Sungkee Lee. Genetic Learning for Adaptive Image Segmentation. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2774-9.

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Book chapters on the topic "Image segmentatio"

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Soille, Pierre. "Segmentation." In Morphological Image Analysis, 267–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-05088-0_9.

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Jähne, Bernd. "Segmentation." In Digital Image Processing, 427–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04781-1_16.

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Awcock, G. J., and R. Thomas. "Segmentation." In Applied Image Processing, 126–47. London: Macmillan Education UK, 1995. http://dx.doi.org/10.1007/978-1-349-13049-8_5.

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Jähne, Bernd. "Segmentation." In Digital Image Processing, 193–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-03174-2_10.

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Jähne, Bernd. "Segmentation." In Digital Image Processing, 193–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-662-21817-4_10.

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Bräunl, Thomas, Stefan Feyrer, Wolfgang Rapf, and Michael Reinhardt. "Segmentation." In Parallel Image Processing, 59–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-662-04327-1_7.

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Sundararajan, D. "Segmentation." In Digital Image Processing, 281–308. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-6113-4_10.

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Soille, Pierre. "Segmentation." In Morphological Image Analysis, 229–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-03939-7_9.

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Jähne, Bernd. "Segmentation." In Digital Image Processing, 193–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-662-11565-7_10.

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Tomita, Fumiaki, and Saburo Tsuji. "Image Segmentation." In Computer Analysis of Visual Textures, 37–55. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-1553-7_3.

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Conference papers on the topic "Image segmentatio"

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Sikander Hayat Khiyal, Malik, Aihab Khan, and Amna Bibi. "Modified Watershed Algorithm for Segmentation of 2D Images." In InSITE 2009: Informing Science + IT Education Conference. Informing Science Institute, 2009. http://dx.doi.org/10.28945/3349.

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With the repaid advancement of computer technology, the use of computer-based technologies is increasing in different fields of life. Image segmentation is an important problem in different fields of image processing and computer vision. Image segmentation is the process of dividing images according to its characteristic e.g., color and objects present in the images. Different methods are presented for image segmentation. The focus of this study is the watershed segmentation. The tool used in this study is MATLAB. Good result of watershed segmentation entirely relay on the image contrast. Image contrast may be degraded during image acquisition. Watershed algorithm can generate over segmentation or under segmentation on badly contrast images. In order to reduce these deficiencies of watershed algorithm a preprocessing step using Random Walk method is performed on input images. Random Walk method is a probabilistic approach, which improves the image contrast in the way image is degraded.
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Xu, Yue, Fei Yin, Zhaoxiang Zhang, and Cheng-Lin Liu. "Multi-task Layout Analysis for Historical Handwritten Documents Using Fully Convolutional Networks." In Twenty-Seventh International Joint Conference on Artificial Intelligence {IJCAI-18}. California: International Joint Conferences on Artificial Intelligence Organization, 2018. http://dx.doi.org/10.24963/ijcai.2018/147.

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Layout analysis is a fundamental process in document image analysis and understanding. It consists of several sub-processes such as page segmentation, text line segmentation, baseline detection and so on. In this work, we propose a multi-task layout analysis method that use a single FCN model to solve the above three problems simultaneously. The FCN is trained to segment the document image into different regions and detect the center line of each text line by classifying pixels into different categories. By supervised learning on document images with pixel-wise labels, the FCN can extract discriminative features and perform pixel-wise classification accurately. After pixel-wise classification, post-processing steps are taken to reduce noises, correct wrong segmentations and find out overlapping regions. Experimental results on the public dataset DIVA-HisDB containing challenging medieval manuscripts demonstrate the effectiveness and superiority of the proposed method.
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Adão, Milena Menezes, Silvio Jamil F. Guimarães, and Zenilton K. G. Patrocı́nio Jr. "Evaluation of machine learning applied to the realignment of hierarchies for image segmentation." In XXXII Conference on Graphics, Patterns and Images. Sociedade Brasileira de Computação - SBC, 2019. http://dx.doi.org/10.5753/sibgrapi.est.2019.8311.

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A hierarchical image segmentation is a set of image segmentations at different detail levels. However, objects can be located at different scales due to their size differences or to their distinct distances from the camera. In literature, many works have been developed to improve hierarchical image segmentation results. One possible solution is to realign the hierarchy such that every region containing an object (or its parts) is at the same level. In this work, we have explored the use of random forest and artificial neural network as regressors models to predict score values for regions belonging to a hierarchy of partitions, which are used to realign it. We have also proposed a new score calculation witch considering all user-defined segmentations that exist in the ground-truth. Experimental results are presented for two different hierarchical segmentation methods. Moreover, an analysis of the adoption of different combination of mid-level features to describe regions and different architectures from random forest and artificial neural network to train regressors models. Experimental results have point out that the use of new proposed score was able to improve final segmentation results.
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Dias, Jeferson de Souza, and José Hiroki Saito. "Coffee plant image segmentation and disease detection using JSEG algorithm." In Workshop de Visão Computacional. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/wvc.2021.18887.

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Brazil is the largest coffee producer in the world, and then there are many challenges to maintain the high quality and purity of the beans. Thus, it is important to study coffee plants, and help agronomists to detect diseases, such as rust, with resources of computer science. In this work, it is described experiments using image segmentation algorithm JSEG, which is capable to segment images in multi-scale. Using a coffee tree image database RoCoLe (Robusta Coffee Leaf Images), the JSEG algorithm is used to segment these images in four scales. It is selected typical segments in each scale and they are grouped using similarity of normalized color histograms. In this way the several scales segmentations are compared. It is concluded that the segments in scales 1 and 2, in which the colors are more homogeneous then in scales 3 and 4, are adequate to use as training samples for the detection of rust diseases.
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Shum, Judy, Adam Goldhammer, Elena DiMartino, and Ender Finol. "CT Imaging of Abdominal Aortic Aneurysms: Semi-Automatic Vessel Wall Detection and Quantification of Wall Thickness." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192638.

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Quantitative measurements of wall thickness in human abdominal aortic aneurysms (AAAs) may provide useful information to predict rupture risk. Our procedure for estimating wall thickness in AAAs includes medical image segmentation and wall thickness detection. Image segmentation requires identifying and segmenting the luminal and outer wall boundaries of the blood vessels and wall thickness can be calculated by using intensity histograms and neural networks. The goal of this study is to develop an image-based, semi-automated method to trace the contours of the vessel wall and measure the wall thickness of the abdominal aorta from in-vivo, contrast-enhanced, CT images. An algorithm for the lumen and inner wall segmentations, and wall thickness detection was developed and tested on 10 ruptured and 10 unruptured AAAs. Reproducibility and repeatability of the algorithm were determined by comparing manual tracings made by two observers to contours made automatically by the algorithm itself. There was a high correspondence between automatic and manual area measurements for the lumen (r = 0.96) and between users (r = 0.98). Based on statistical analyses, the algorithm tends to underestimate the lumen area when compared to both observers.
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Li, Shaohua, Xiuchao Sui, Xiangde Luo, Xinxing Xu, Yong Liu, and Rick Goh. "Medical Image Segmentation using Squeeze-and-Expansion Transformers." In Thirtieth International Joint Conference on Artificial Intelligence {IJCAI-21}. California: International Joint Conferences on Artificial Intelligence Organization, 2021. http://dx.doi.org/10.24963/ijcai.2021/112.

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Medical image segmentation is important for computer-aided diagnosis. Good segmentation demands the model to see the big picture and fine details simultaneously, i.e., to learn image features that incorporate large context while keep high spatial resolutions. To approach this goal, the most widely used methods -- U-Net and variants, extract and fuse multi-scale features. However, the fused features still have small "effective receptive fields" with a focus on local image cues, limiting their performance. In this work, we propose Segtran, an alternative segmentation framework based on transformers, which have unlimited "effective receptive fields" even at high feature resolutions. The core of Segtran is a novel Squeeze-and-Expansion transformer: a squeezed attention block regularizes the self attention of transformers, and an expansion block learns diversified representations. Additionally, we propose a new positional encoding scheme for transformers, imposing a continuity inductive bias for images. Experiments were performed on 2D and 3D medical image segmentation tasks: optic disc/cup segmentation in fundus images (REFUGE'20 challenge), polyp segmentation in colonoscopy images, and brain tumor segmentation in MRI scans (BraTS'19 challenge). Compared with representative existing methods, Segtran consistently achieved the highest segmentation accuracy, and exhibited good cross-domain generalization capabilities.
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Hage, Ilige S., and Ramsey F. Hamade. "Segregation of Cortical Bone’s Haversian Systems via Automated Image Segmentation." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51872.

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The lamellar or Haversian system is comprised mainly of fundamental units “osteons”. Haversian canals run through the center of the osteons where one or more blood vessels are located. The bone matrix is comprised of concentric lamellae surrounding Haversian canals. Those lamellae are punctuated by holes called lacunae, which are connected to each other through the canaliculi supplying nutrients. Haversian canals, lacunae and canaliculi of the Haversian system constitute the main porosities in cortical bone, thus it is advantageous to segregate those systems in segmented images that will help medical image analysis in accounting for porosities. To the authors’ best knowledge, no work has been published on segregating Haversian systems with its 3 predominant components (Haversian canals, lacunae, and canaliculi) via automated image segmentation of optical microscope images. This paper aims to detect individual osteonal Haversian system via optical microscope image segmentation. Automation is assured via artificial intelligence; specifically neural networks are used to procure an automated image segmentation methodology. Biopsies are taken from cortical bone cut at mid-diaphysis femur from bovine cows (which age is about 2 year-old). Specimens followed a pathological procedure (fixation, decalcification, and staining using H&E staining treatment) in order to get slides ready for optical imaging. Optical images at 20X magnification are captured using SC30 digital microscope camera of BX-41M LED optical Olympus microscope. In order to get the targeted segmented images, utilized was an image segmentation methodology developed previously by the authors. This methodology named “PCNN-PSO-AT” combines pulse coupled neural networks to particle swarm optimization and adaptive thresholding, yielding segmented images quality. Segmentation is occurred based on a geometrical attribute namely orientation used as the fitness function for the PSO. The fitness function is built in such way to maximize the identified number of features (which are the 3 components of the osteonal system) having same orientation. The segmentation methodology is applied on several test images. Results were compared to manually segmented images using suitable quality metrics widely used for image segmentation evaluation namely precision rate, sensitivity, specificity, accuracy and dice. The main goal of segmentation algorithms is to capture as accurate as possible structures of interest, herein Haversian (osteonal) system. High quality segmented images obtained as well as high values of quality metrics (approaching unity) prove the robustness of the segmentation methodology in reaching high fidelity segments of the Haversian system.
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Alqahtani, Hussain, Naif Alqahtani, Ryan T. Armstrong, and Peyman Mostaghimi. "Segmentation of X-Ray Images of Rocks Using Supervoxels Over-Segmentation." In International Petroleum Technology Conference. IPTC, 2022. http://dx.doi.org/10.2523/iptc-22131-ms.

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Abstract Digital core analysis has gained the interest of many scientific communities because of its impact on our understanding of flow in porous media. A typical workflow in digital core analysis includes scanning, reconstruction, denoising, segmentation, and modeling. Image analysis and modeling highly depend on the quality of the segmentation step. In this regard, conventional image segmentation methods often require user input/interference. This results in user bias and may produce a range of possible segmentation outcomes. To address this, we propose an unsupervised machine learning framework that offers multiple functionalities including improved mineral and micro-porosity identification. Superpixel (2D) and (3D) work by over-segmenting greyscale images using a family of over-segmentation algorithms. Simple Linear Iterative Clustering (SLIC) is one of these algorithms that is recognized for its speed and memory efficiency. The proposed framework utilizes SLIC and unsupervised clustering methods for segmenting greyscale images. SLIC divides the 2D and 3D images into segments having pixels (or voxels) with similar features (i.e., intensity range). Statistical features of each segment are computed and used for identifying the segment label through unsupervised clustering techniques. The unsupervised voting clustering implements a majority voting policy from multiple clustering algorithms including Hierarchical clustering and k-means clustering. A North Sea sandstone 2D X-ray image along with its SEM image were used to validate this framework. Different metrics were used to measure the accuracy of the X-ray segmentation with SEM segmentation. Our results show a mean Jaccard index of 70% and a mean Dice index of 81%. The same workflow is applied using supervoxels on a high-resolution 3D Indiana Limestone image and the results show similar accuracy margins compared to watershed segmentation. Comparison with other segmentation methods shows an average Jaccard score of 74% and an average Dice index score of 83%. To the best of our knowledge, this is the first application of superpixels over-segmentation algorithms in semantic segmentation of X-ray micro-CT images of porous media. The findings of this study highlighted the advantage of these algorithms in detecting sub-resolution porosity regions in greyscale images and obtaining accurate multi-label segmentation.
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Mansilla, Lucy, and Paulo Miranda. "Image Segmentation by Image Foresting Transform with Boundary Polarity and Shape Constraints." In XXVIII Concurso de Teses e Dissertações da SBC. Sociedade Brasileira de Computação - SBC, 2020. http://dx.doi.org/10.5753/ctd.2015.10003.

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Image segmentation, such as to extract an object from a background, is very useful for medical and biological image analysis. In this work, we propose new segmentation methods for interactive segmentation of multidimensional images, based on the Image Foresting Transform (IFT), by exploiting for the first time non-smooth connectivity functions (NSCF) with a strong theoretical background. The new algorithms provide global optimum solutions according to an energy function of graph cut, subject to high-level boundary constraints (polarity and shape). Our experimental results indicate substantial improvements in accuracy in relation to other state-of-the-art methods, using medical images by allowing the customization of the segmentation to a given target object.
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Zhupanska, Olesya I. "On the Role of Segmentation in the Analysis of Micro-CT Data of Impact Damage in the CFRP Composites." In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-11037.

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Abstract In this paper we discuss the role of different image segmentation methods that are used for the analysis of the micro computed tomography (micro-CT) data of damage in the carbon fiber reinforced polymer (CFRP) composites due to low velocity impact. Segmentation is one of the most critical steps in the image processing of the three dimensional (3D) CT data and accurate assessment of the damage from CT data depends to a great extent on the image segmentation. We have extensively studied low velocity impact damage in the CFRP composites using 3D CT. CFRP textile composite laminates were impacted using an Instron 8200 Dynatup drop-weight impact machine. ZEISS METROTOM 1500 CT scanner was used to evaluate internal impact damage. VGStudio MAX was used for reconstruction of CT images. Different segmentation procedures were used during image processing of the CT images. Differences in the estimates of the damage zone obtained using different segmentation techniques have been assessed.
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Reports on the topic "Image segmentatio"

1

Sharma, Karan. The Link Between Image Segmentation and Image Recognition. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.199.

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Kim, A., I. Pollak, H. Krim, and A. S. Willsky. Scale-Based Robust Image Segmentation. Fort Belvoir, VA: Defense Technical Information Center, March 1997. http://dx.doi.org/10.21236/ada457838.

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Franaszek, Marek. Gauging Difficulty of Image Segmentation. Gaithersburg, MD: National Institute of Standards and Technology, 2022. http://dx.doi.org/10.6028/nist.tn.2207.

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Ekeland, I., P. L. Lions, Y. Meyer, and J. M. Morel. Vibrations, Viscosity, Wavelets and Image Segmentation. Fort Belvoir, VA: Defense Technical Information Center, January 1990. http://dx.doi.org/10.21236/ada225750.

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Franaszek, Marek. Gauging the difficulty of image segmentation. Gaithersburg, MD: National Institute of Standards and Technology, 2022. http://dx.doi.org/10.6028/nist.tn.2207-upd1.

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Shaw, K. B., and M. C. Lohrenz. A Survey of Digital Image Segmentation Algorithms. Fort Belvoir, VA: Defense Technical Information Center, January 1995. http://dx.doi.org/10.21236/ada499374.

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Ghosh, Payel. Medical Image Segmentation Using a Genetic Algorithm. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.25.

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Shah, Jayant. Object Oriented Segmentation of Images. Fort Belvoir, VA: Defense Technical Information Center, December 1994. http://dx.doi.org/10.21236/ada290792.

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Xu, Y., and E. C. Uberbacher. 2-D image segmentation using minimum spanning trees. Office of Scientific and Technical Information (OSTI), September 1995. http://dx.doi.org/10.2172/113991.

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Wu, Jin Chu, Michael Halter, Raghu N. Kacker, John T. Elliot, and Anne L. Plant. Measurement uncertainty in cell image segmentation data analysis. National Institute of Standards and Technology, August 2013. http://dx.doi.org/10.6028/nist.ir.7954.

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