Academic literature on the topic 'IGFBP1'

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Journal articles on the topic "IGFBP1"

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Czogała, Wojciech, Wojciech Strojny, Przemysław Tomasik, et al. "The Insight into Insulin-Like Growth Factors and Insulin-Like Growth-Factor-Binding Proteins and Metabolic Profile in Pediatric Obesity." Nutrients 13, no. 7 (2021): 2432. http://dx.doi.org/10.3390/nu13072432.

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Insulin-like growth factors (IGFs) and insulin-like growth-factor-binding proteins (IGFBPs) regulate cell proliferation and differentiation and may be of importance in obesity development. The aim of the study was to analyze the expression of chosen IGF-axis genes and the concentration of their protein products in 28 obese children (OB) and 34 healthy control (HC), and their correlation with essential parameters associated with childhood obesity. The gene expression of IGFBP7 was higher, and the expression of IGF2 and IGFBP1 genes was lower in the OB. The expression of IGFBP6 tended to be lowe
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Zhong, Zhenglan, Xiaoping Xu, Shiguo Han, Yongxiang Shao, and Yong Yi. "Comprehensive Analysis of Prognostic Value and Immune Infiltration of IGFBP Family Members in Glioblastoma." Journal of Healthcare Engineering 2022 (July 4, 2022): 1–13. http://dx.doi.org/10.1155/2022/2929695.

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Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. The insulin-like growth factor-binding protein (IGFBP) family is involved in tumorigenesis and the development of multiple cancers. However, little is known about the prognostic value and regulatory mechanisms of IGFBPs in GBM. Oncomine, Gene Expression Profiling Interactive Analysis, PrognoScan, cBioPortal, LinkedOmics, TIMER, and TISIDB were used to analyze the differential expression, prognostic value, genetic alteration, biological function, and immune cell infiltration of IGFBPs in GBM. We observed that IGFBP1,
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Zheng, Ruoyi, Wenming Chen, Weiting Xia, Jingyu Zheng, and Qing Zhou. "The Prognostic Values of the Insulin-Like Growth Factor Binding Protein Family in Ovarian Cancer." BioMed Research International 2020 (November 16, 2020): 1–15. http://dx.doi.org/10.1155/2020/7658782.

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Purpose. To assess the expression of insulin-like growth factor binding protein (IGFBP) family and its prognostic impact in ovarian cancer (OC) patients. Materials and Methods. The mRNA expression and protein expression of individual IGFBPs in healthy ovarian samples and OC tissues were explored through Oncomine, Gene Expression Profiling Interactive Analysis, and Human Protein Atlas database. Additionally, the prognostic values of the six IGFBP members in patients with OC were evaluated by Kaplan-Meier plotter. Results. IGFBP2 and IGFBP4 mRNA expression were remarkably upregulated in patients
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Minchenko, Dmytro O., D. O. Tsymbal, O. P. Yavorovsky, N. V. Solokha, and O. H. Minchenko. "Expression of genes encoding IGFBPs, SNARK, CD36, and PECAM1 in the liver of mice treated with chromium disilicide and titanium nitride nanoparticles." Endocrine Regulations 51, no. 2 (2017): 84–95. http://dx.doi.org/10.1515/enr-2017-0008.

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AbstractObjective. The aim of the present study was to examine the effect of chromium disilicide and titanium nitride nanoparticles on the expression level of genes encoding important regulatory factors (IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, SNARK/NUAK2, CD36, and PECAM1/CD31) in mouse liver for evaluation of possible toxic effects of these nanoparticles.Methods. Male mice received 20 mg chromium disilicide nanoparticles (45 nm) and titanium nitride nanoparticles (20 nm) with food every working day for 2 months. The expression of IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, SNARK, CD36, and PECAM
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Rehman, Muhammad Saif-ur, Muqeet Mushtaq, Faiz-ul Hassan, Zia-ur Rehman, Muhammad Mushahid, and Borhan Shokrollahi. "Comparative Genomic Characterization of Insulin-Like Growth Factor Binding Proteins in Cattle and Buffalo." BioMed Research International 2022 (July 25, 2022): 1–15. http://dx.doi.org/10.1155/2022/5893825.

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The somatotropic axis consists of genes associated with economic traits like muscle growth and carcass traits in livestock. Insulin-like growth factor binding proteins (IGFBPs) are the major proteins that play a vital role in the somatotropic axis. The present study performed a genome-wide characterization of IGFBP genes in cattle. Genomic sequences of the IGFBP gene family for different mammals (cattle, buffalo, goat, and sheep) were recovered from the NCBI database. Sequence analyses were performed to investigate cattle’s genomic variations in the IGFBP gene family. Phylogenetic analysis, ge
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Simmons, Rebecca M., David W. Erikson, Jinyoung Kim, et al. "Insulin-Like Growth Factor Binding Protein-1 in the Ruminant Uterus: Potential Endometrial Marker and Regulator of Conceptus Elongation." Endocrinology 150, no. 9 (2009): 4295–305. http://dx.doi.org/10.1210/en.2009-0060.

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Abstract Establishment of pregnancy in ruminants requires conceptus elongation and production of interferon-τ (IFNT), the pregnancy recognition signal that maintains ovarian progesterone (P4) production. These studies determined temporal and spatial alterations in IGF binding protein (IGFBP)-1 and IGFBP3 in the ovine and bovine uterus; effects of P4 and IFNT on their expression in the ovine uterus; and effects of IGFBP1 on ovine trophectoderm cell proliferation, migration, and attachment. IGFBP1 and IGFBP3 were studied because they are the only IGFBPs specifically expressed by the endometrial
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Fouque, D., Y. Le Bouc, M. Laville, et al. "Insulin-like growth factor-1 and its binding proteins during a low-protein diet in chronic renal failure." Journal of the American Society of Nephrology 6, no. 5 (1995): 1427–33. http://dx.doi.org/10.1681/asn.v651427.

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The effects of a low-protein diet on the serum insulin-like growth factor (IGF)-1 and IGF binding proteins (IGFBP) were investigated during a 3-month controlled study in 12 adult chronic renal failure patients. Six patients were randomly supplemented with keto acids (Cetolog, Clintec, Velizy, France). Protein intake was prescribed so that both groups were isonitrogenous. Dietary survey included a monthly 3-day food record and a 24-h urinary urea measurement. After a 4- to 6-wk equilibrium period (1.11 g of protein, 32 kcal/kg body wt per day), patients reduced their protein intake to 0.71 g pr
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Alterki, Abdulmohsen, Eman Al Shawaf, Irina Al-Khairi, et al. "The Rise of IGFBP4 in People with Obstructive Sleep Apnea and Multilevel Sleep Surgery Recovers Its Basal Levels." Disease Markers 2021 (October 4, 2021): 1–9. http://dx.doi.org/10.1155/2021/1219593.

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IGFBP4 is the smallest member of the insulin-like growth factor binding protein family (IGFBP). It is a hepatic protein that plays a role in modulating the activity and bioavailability of IGF-I. The expression of IGFBP4 was found to increase under conditions of hypoxia. Obstructive sleep apnea (OSA) is a common disorder, characterized by cyclic episodes of intermittent hypoxia and fragmented sleep. Our aim was to quantify levels of circulating IGFBP1, IGFBP2, IGFBP3, IGFBP4, and IGFBP7 in fasting plasma samples of 69 Kuwaiti participants and explore its correlation with indices of OSA. The qua
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Alterki, Abdulmohsen, Eman Al Shawaf, Irina Al-Khairi, et al. "The Rise of IGFBP4 in People with Obstructive Sleep Apnea and Multilevel Sleep Surgery Recovers Its Basal Levels." Disease Markers 2021 (October 4, 2021): 1–9. http://dx.doi.org/10.1155/2021/1219593.

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IGFBP4 is the smallest member of the insulin-like growth factor binding protein family (IGFBP). It is a hepatic protein that plays a role in modulating the activity and bioavailability of IGF-I. The expression of IGFBP4 was found to increase under conditions of hypoxia. Obstructive sleep apnea (OSA) is a common disorder, characterized by cyclic episodes of intermittent hypoxia and fragmented sleep. Our aim was to quantify levels of circulating IGFBP1, IGFBP2, IGFBP3, IGFBP4, and IGFBP7 in fasting plasma samples of 69 Kuwaiti participants and explore its correlation with indices of OSA. The qua
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Kharkova, A., D. Minchenko, D. Tsymbal, and O. Minchenko. "Expression of IGFBP1, IGFBP2 and IGF2BP3 genes in U87 glioma cells with suppressed ERN1 signaling enzyme function in glutamine and glucose deprivation conditions." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 68, no. 3 (2014): 24–29. http://dx.doi.org/10.17721/1728_2748.2014.68.24-29.

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Insulin-like growth factor binding proteins play an important role in the regulation of cell proliferation and malignant tumor growth. It was shown that blockade of both enzymatic functions of sensor and signaling enzyme ERN1 (from endoplasmic reticulum to nuclei-1), the major component of endoplasmic reticulum stress signaling, decreases the expression level of IGFBP1, IGFBP2 and IGF2BP3 genes in U87 glioma cell. The decreased level of these gene expressions in glioma cells with ERN1 signaling enzyme loss of function correlates with suppression of cell proliferation. It was shown that glutami
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Dissertations / Theses on the topic "IGFBP1"

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Matz-Soja, Madlen, and Rolf Gebhardt. "Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-142560.

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Background Hedgehog signaling plays an important role in embryonic development, organogenesis and cancer. In the adult liver, Hedgehog signaling in non-parenchymal cells has been found to play a role in certain disease states such as fibrosis and cirrhosis. However, whether the Hedgehog pathway is active in mature healthy hepatocytes and is of significance to liver function are controversial. Findings Two types of mice with distinct conditional hepatic deletion of the Smoothened gene, an essential co-receptor protein of the Hedgehog pathway, were generated for investigating the role of Hedgeho
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Green, Charmaine. "THE ROLE OF INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR SIGNALLING IN THE MOUSE EMBRYO DURING PREIMPLANTATION DEVELOPMENT AND EARLY IMPLANTATION." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/17684.

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The use of assisted reproductive technologies (ART) such as in vitro fertilisation (IVF) is increasing and today close to 4 percent of babies born in Australia, are as a result of ART. IVF procedures involve the culture of resultant embryos in medium that routinely lacks the growth factors that are present in the reproductive tract. Cultured embryos develop at a slower rate and have higher levels of developmental arrest, with fewer than 50% of embryos reaching the blastocyst stage. Furthermore, once an embryo is transferred back into the uterus, it faces the hurdle of implantation, with implan
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Lin, Wan-Jung. "The nuclear actions of IGFBP-3." Online access for everyone, 2006. http://www.dissertations.wsu.edu/Thesis/Summer2006/w%5Flin%5F072606.pdf.

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Eddiry, Sanaa. "Rôle du SNORD116 et de l'IGFBP7 dans la réponse à l'IGF1 dans le syndrome de Prader-Willi." Toulouse 3, 2013. http://www.theses.fr/2013TOU30215.

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Le syndrome de Prader-Willi (SPW) est une maladie génétique complexe du développement qui résulte de l'absence d'expression de gènes sur le chromosome15q11-q13 paternel. Les patients SPW présentent des taux de GH diminués et des taux de ghréline élevés. Ils sont traités précocement par GH. La région du chromosome 15q11-q13 responsable du SPW est soumise au phénomène d'empreinte génétique, des études récentes la limitent à une région minimale incluant un cluster de small nucleolar RNA (snoARN): le SNORD116. Nos résultats montrent une sensibilité accrue à l'IGF1 et à l'insuline dans les fibrobla
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Grosse, Christina Maria. "Knochenalterassozierte IGF-I und IGFBP-3 Befunde." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-93014.

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HO, Penny Pei-Ying. "NOVEL IGF-INDEPENDENT MECHANISMS OF IGFBP-5." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10010.

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Insulin-like growth factor binding proteins (IGFBPs) are a group of six structurally similar proteins that modulates the mitogenic actions of IGFs through high binding affinity. IGFBP-5 and -3 has been reported to function independently of their IGF-binding ability and this involves interaction with several non-IGF proteins. Yeast two-hybrid and co immunoprecipitation (co-IP) assays identified SPRY2 and GADD34 as novel IGFBP-5-interacting partners. In MCF 10A cells, IGFBP 5:SPRY2 interaction potentiated SPRY2-mediated inhibition to EGF-stimulated DNA synthesis while IGFBP-5 expression alone ha
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TROTTA, ROSA. "A novel biomarker for cancer and autoimmune diseases: IGFBP6." Doctoral thesis, Università degli Studi di Foggia, 2019. http://hdl.handle.net/11369/382356.

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La temperatura corporea costituisce un importante meccanismo di difesa ed è il risultato di una complessa interazione che coinvolge numerosi fattori. Nell'uomo sano, la temperatura corporea è finemente regolata; deviazioni di 0.5°C oltre il limite superiore possono indicare una condizione patologica. Numerosi agenti possono indurre ipertermia, tra cui, insufficienza cardiaca acuta/cardiomiopatia acuta da stress [1] e infarto miocardico acuto [2] sindrome neurolettica maligna [3], endocrinopatie [4, 5], disturbi del sistema nervoso centrale (SNC) [6] e patologie oncologiche [7]. Le temperature
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Pillai, Chitra Claire. "IGFPBp1 : a multifunctional role in implantation, embryonic and fetal development." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271064.

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Paula, Mariana Teresa Alves Sarti de. "Estudo da expressão do IGF1R mRNA em meninas com puberdade precoce central antes e durante o tratamento com análogos do GnRH." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/17/17144/tde-20072016-142344/.

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INTRODUÇÃO Na puberdade, tanto fisiológica quanto precoce, um dos eventos marcantes é o estirão de crescimento. Análogos do GnRH tem sido utilizado como tratamento da puberdade precoce central (PPC) tendo como consequência o bloqueio do eixo gonadal e diminuição da velocidade de crescimento, porém mantém níveis séricos elevados de IGF-I e IGFBP-3. Não existem relatos sobre a expressão do IGF1R durante a puberdade. Considerando-se que este poderia ser um ponto de regulação da velocidade de crescimento, o presente estudo propõe avaliar a expressão do IGF1R em meninas com PPC antes e durante o tr
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Wilhelm, Franziska Katharina. "Der PI3K/AKT/mTOR-Signalweg und die Produktion des Insulinähnlichen Wachstumsfaktorbindungsproteins-2 (IGFBP-2) in humanen Adipozyten." Doctoral thesis, Universitätsbibliothek Leipzig, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-219991.

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In den letzten Jahren wurde gezeigt, dass die Serumkonzentration des insulinähnlichen Wachstumsfaktorbindungsproteins-2 (IGFBP-2) bei Krebserkrankungen, die mit dem Verlust des Tumorsuppressorgens PTEN einhergehen, erhöht ist und daher möglicherweise einen Marker für den PTEN-Status und die Aktivität des PI3K/AKT/mTOR-Signalweges darstellt. Schmid et al. haben 2014 einen Patienten mit PTEN-Hamartom-Tumor-Syndrom (PHTS) mit einer heterozygoten PTEN-Keimbahndeletion und massiver Lipomatose beschrieben, bei dem erhöhte IGFBP-2 Serumspiegel gemessen wurden. Ziel dieser Arbeit war es zu analysiere
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Books on the topic "IGFBP1"

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Lai, Joe Heng. A polymorphic locus in the promoter region of the IGFBP3 gene is associated with mammographic breast density. National Library of Canada, 2003.

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Rauschnabel, Uta. RGD-spezifische Bindung von Insulin-ähnlichen Wachstumsfaktor Bindungsprotein 2 (IGFBP-2) an [alpha]5[beta]1-Integrinrezeptoren [alpha beta-Integrinrezeptoren] auf der Oberfläche von Ewingsarkom Zellen und IGF-unabhängige Effekte. U. Rauschnabel, 2000.

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Hoeflich, Andreas, John Pintar, and Briony Forbes, eds. Current Perspectives on Insulin-like Growth Factor Binding Protein (IGFBP) Research. Frontiers Media SA, 2019. http://dx.doi.org/10.3389/978-2-88945-718-2.

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Perks, Claire, and Shin-Ichiro Takahashi, eds. The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-142-5.

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F. Moosavinasab, J. Ghiasi Ghalehkand, O. Ghanbari, and S. Hassanpour. In ovo injection of IGF1 improves intestinal enzyme activity in broilers. Verlag Eugen Ulmer, 2015. http://dx.doi.org/10.1399/eps.2015.94.

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Book chapters on the topic "IGFBP1"

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van Roy, Frans, Volker Nimmrich, Anton Bespalov, et al. "CCN3: NOV, IGFBP9, IGFBP-rP3." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100183.

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van Roy, Frans, Volker Nimmrich, Anton Bespalov, et al. "CCN1: Cyr61, CEF10, ßIG-M1, IGFBP10, IGFBP-rP4." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100181.

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van Roy, Frans, Volker Nimmrich, Anton Bespalov, et al. "CCN2: CTGF, FISP12, HCS24, ßIG-M2, HBGF-0.8, Ecogenin, IGFBP8, IGFBP-rP2." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100182.

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Fang, Peng, Vivian Hwa, and Ron Rosenfeld. "IGFBPs and Cancer." In Biology of IGF-1: Its Interaction with Insulin in Health and Malignant States. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/0470869976.ch14.

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Savage, M. O., J. C. Blair, A. J. Jorge, M. E. Street, M. B. Ranke, and C. Camacho-Hübner. "IGFs and IGFBPs in GH Insensitivity." In IGF-I and IGF Binding Proteins. KARGER, 2005. http://dx.doi.org/10.1159/000085760.

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Powell, David R., Phillip D. K. Lee, and Adisak Suwanichkul. "Multihormonal Regulation of IGFBP-1 Promoter Activity." In Advances in Experimental Medicine and Biology. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2988-0_20.

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Aimaretti, Gianluca, Roberto Baldelli, Ginevra Corneli, et al. "IGFs and IGFBPs in Adult Growth Hormone Deficiency." In IGF-I and IGF Binding Proteins. KARGER, 2005. http://dx.doi.org/10.1159/000085758.

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Huynh, HoangDinh, Megan Kaba, Sonali Rudra, et al. "IGFBP2 Supports ex vivo Expansion of Hematopoietic Stem Cells." In Research and Perspectives in Endocrine Interactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04302-4_3.

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Holly, Jeff M. P., and Janet K. Fernihough. "The Insulin-Like Growth Factor (IGF) Binding Proteins (IGFBPS)." In Growth Hormone. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-5163-8_5.

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Mesotten, Dieter, and Greet Van den Berghe. "Changes Within the GH/IGF-I/IGFBP Axis in Critical Illness." In Acute Endocrinology. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-177-6_9.

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Conference papers on the topic "IGFBP1"

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Slater, Tom, Alexander-Francisco Bruns, and Stephen Wheatcroft. "117 The divergent effects of IGFBP1 and IGFBP2 on vascular endothelial function." In British Cardiovascular Society Annual Conference ‘High Performing Teams’, 4–6 June 2018, Manchester, UK. BMJ Publishing Group Ltd and British Cardiovascular Society, 2018. http://dx.doi.org/10.1136/heartjnl-2018-bcs.116.

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LeRoy, Elizabeth C., Elizabeth T. Jacobs, Erin L. Ashbeck, et al. "Abstract 2853: Genetic variation in IGF1, GHR, and IGFBP1 is associated with colorectal cancer." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-2853.

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Kim, Jin Cheon, Ye Jin Ha, Ka Hee Tak, et al. "Abstract 1641: Complex behavior of ALDH1A1 and IGFBP1 in liver metastasis of colorectal cancer." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1641.

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Ungurs, O., M. Vetter, N. Pazaitis, J. Beer, C. Thomssen, and C. Wickenhauser. "Expression von IGF2BP1 in Ovarialkarzinomen." In 12. Jahrestagung der Mitteldeutschen Gesellschaft für Frauenheilkunde und Geburtshilfe e.V. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1645902.

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Backu, E., E. Aschenbrenner, K. Pollinger, et al. "Relevanz von IGFBP2 im hepatozellulären Karzinom." In Viszeralmedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1695235.

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Ahasic, Amy M., Rihong Zhai, Li Su, et al. "IGFBP3 Polymorphism Is Associated With Plasma Insulin-Like Growth Factor (IGF)-1 And Insulin-Like Growth Factor Binding Protein (IGFBP-3) In An Intensive Care Unit (ICU) Cohort." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3545.

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Lohse, M., D. Gschwind, E. Aschenbrenner, et al. "Die p53-Familie reguliert IGFBP2 beim hepatozellulären Karzinom." In Viszeralmedizin 2017. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1605129.

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Fathy, A., M. Habeb, S. Embarak, M. M. Zalat, and N. A. A. Oweedah. "Non-Invasive IGFBP 1 and IGFBP 2 Biomarkers as Predictors of Therapy and Outcomes in Usual Interstitial Pneumonia." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3079.

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Guiot, Julien, Monique Henket, Jean-Louis Corhay, and Renaud Louis. "Serum IGFBP2 as a marker of idiopathic pulmonary fibrosis." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa3840.

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Kolligs, F., E. Backu, D. Gschwind, et al. "Dosisabhängige Effekte von IGFBP2 auf die Viabilität von Hepatomzellen." In Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV). Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1733618.

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Reports on the topic "IGFBP1"

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Schoen, Timothy J. Expression and Characterization of Insulin-Like Growth Factor Binding Proteins (IGFBPs) and IGFBP-2 mRNA in the Developing Chicken Eye. Defense Technical Information Center, 1995. http://dx.doi.org/10.21236/ad1011459.

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Funkenstein, Bruria, and Cunming Duan. GH-IGF Axis in Sparus aurata: Possible Applications to Genetic Selection. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7580665.bard.

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Many factors affect growth rate in fish: environmental, nutritional, genetics and endogenous (physiological) factors. Endogenous control of growth is very complex and many hormone systems are involved. Nevertheless, it is well accepted that growth hormone (GH) plays a major role in stimulating somatic growth. Although it is now clear that most, if not all, components of the GH-IGF axis exist in fish, we are still far from understanding how fish grow. In our project we used as the experimental system a marine fish, the gilthead sea bream (Sparus aurata), which inhabits lagoons along the Mediter
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Yee, Douglas A. Prevention of Breast Cancer by IGFBP. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada405491.

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Yee, Douglas A. Prevention of Breast Cancer in IGFBP. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada431788.

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Yee, Douglas. Prevention of Breast Cancer in IGFBP. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada421773.

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Chen, Xiaole, Peng Wang, Yunquan Luo, et al. Therapeutic Efficacy Evaluation and Underlying Mechanisms Prediction of Jianpi Liqi Decoction for Hepatocellular Carcinoma. Science Repository, 2021. http://dx.doi.org/10.31487/j.jso.2021.02.04.sup.

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Abstract:
Objective: The aim of this study was to assess the therapeutic effects of Jianpi Liqi decoction (JPLQD) in hepatocellular carcinoma (HCC) and explore its underlying mechanisms. Methods: The characteristics and outcomes of HCC patients with intermediate stage B who underwent sequential conventional transcatheter arterial chemoembolization (cTACE) and radiofrequency ablation (RFA) only or in conjunction with JPLQD were analysed retrospectively. The plasma proteins were screened using label-free quantitative proteomics analysis. The effective mechanisms of JPLQD were predicted through network pha
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Cobb, Laura. Understanding the Apoptotic Functions of IGFBP-3 in Prostate Cancer. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada593327.

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Cobb, Laura, and Pinchas Cohen. Understanding the Apoptotic Functions of IGFBP-3 in Prostate Cancer. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada464008.

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Oh, Youngman. Role of IGFBP-3/IGFBP-3 Receptor Interaction in Normal and Malignant Mammary Growth: A Potential Diagnostic Parameter and New Strategy for Endocrine Therapy. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada392333.

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Zhang, Wei. The Cellular Localization of IGFBP5 Determines its Oncogenic Functions in Breast Cancer. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada457676.

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