Relevant bibliographies by topics / IFM development

Academic literature on the topic 'IFM development'

Author: Grafiati
Published: 6 September 2023

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Journal articles on the topic "IFM development"

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Babu, Sajesh, and Nallur B. Ramachandra. "Screen for new mutations on the 2nd chromosome involved in indirect flight muscle development in Drosophila melanogaster." Genome 50, no. 4 (April 2007): 343–50. http://dx.doi.org/10.1139/g07-012.

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An extensive ethylmethanesulfonate mutagenesis of Drosophila melanogaster was undertaken to isolate the stronger alleles of 3 indirect flight-muscle mutations. We isolated 17 strong mutant lines, with nearly complete penetrance and expressivity, using direct screening under polarized light, from more than 1700 mutagenized chromosomes. On complementation, we found 11 of these 17 mutant lines to be alleles of 3 indirect flight-muscle mutations (Ifm(2)RU1, 3 noncomplementing lines; ifm(2)RU2, 6 alleles; ifm(2)RU3, 2 alleles) of the previously isolated 8 complementation groups (Ifm(2)RU1to ifm(2)RU8). In addition, we found 6 new complementation groups with strong defects in adult-muscle morphology; we named these ifm(2)RS1 to ifm(2)RS6. All mutant lines were mapped by meiotic recombination, and 5 of the 6 new complementation lines were mapped using chromosome deficiencies. ifm(2)RS1 maps to a region that harbors ifm(2)RU4 (a mutation that was isolated previously); however, theses are not alleles because each complements the other mutation, and the mutant-muscle phenotype is very different. We used direct screening under polarized light to find recessive mutations; although this method was labor intensive, it can be used to identify recessive genes involved in myogenesis, unlike screens for flightlessness or wing-position defects. This screen identifies regions on the second chromosome that harbor probable genes that are likely expressed in the mesoderm and are thought to be involved in myogenesis. This screen has generated valuable resources that will help us to understand the role of many molecular players involved in myogenesis.
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Haji, Mona, Laoucine Kerbache, and Tareq Al-Ansari. "Development of Risk Management Mitigation Plans for the Infant Formula Milk Supply Chain Using an AHP Model." Applied Sciences 13, no. 13 (June 29, 2023): 7686. http://dx.doi.org/10.3390/app13137686.

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Infant formula milk (IFM) is critical in the diet of many babies and must be of high-quality. Unfortunately, IFM has been a target of adulteration by those attempting to make illegal profits and has suffered from contamination-related issues. This study’s main objective was to identify the most critical risks affecting IFM quality in the supply chain and determine mitigation strategies to improve IFM performance measurement. We developed a model to reduce adulteration and contamination rates in the infant formula milk supply chains (IFMSCs) and maximize safety. The steps to achieve the study’s objectives included: (1) identifying the importance of IFMs for infant nutrition and their risks; (2) establishing mitigation criteria for evaluating IFMSC’s performance to maximize quality; and (3) analyzing each mitigation criterion to maximize IFM safety. Based on pairwise comparisons by professionals in the food supply chain (FSC) of decision-making, the Analytic Hierarchy Process (AHP) model was used to analyze and prioritize mitigation alternatives. According to the contamination quality risk agent, mitigation alternative (QR.M2) ranked highest. This study’s findings illustrate how vital avoiding risk is when dealing with public health, especially infants’ health, and how IFM must undergo precise testing and quality checks at every supply chain stage to ensure quality.
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Asemu, Girma, Kelly A. O'Connell, James W. Cox, Erinne R. Dabkowski, Wenhong Xu, Rogerio F. Ribeiro, Kadambari C. Shekar, et al. "Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion." American Journal of Physiology-Heart and Circulatory Physiology 304, no. 4 (February 15, 2013): H514—H528. http://dx.doi.org/10.1152/ajpheart.00674.2012.

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Functional differences between subsarcolemmal and interfibrillar cardiac mitochondria (SSM and IFM) have been observed with aging and pathological conditions in rodents. Results are contradictory, and there is little information from large animal models. We assessed the respiratory function and resistance to mitochondrial permeability transition (MPT) in SSM and IFM from healthy young (1 yr) and old (8 yr) female beagles and in old beagles with hypertension and left ventricular (LV) wall thickening induced by 16 wk of aldosterone infusion. MPT was assessed in SSM and IFM by Ca2+ retention and swelling. Healthy young and old beagles had similar mitochondrial structure, respiratory function, and Ca2+-induced MPT within SSM and IFM subpopulations. On the other hand, oxidative capacity and resistance to Ca2+-induced MPT were significantly greater in IFM compared with SSM in all groups. Old beagles treated with aldosterone had greater LV wall thickness and worse diastolic filling but normal LV chamber volume and systolic function. Treatment with aldosterone did not alter mitochondrial respiratory function but accelerated Ca2+-induced MPT in SSM, but not IFM, compared with healthy old and young beagles. In conclusion, in a large animal model, oxidative capacity and resistance to MPT were greater in IFM than in SSM. Furthermore, aldosterone infusion increased susceptibility to MPT in SSM, but not IFM. Together this suggests that SSM are less resilient to acute stress than IFM in the healthy heart and are more susceptible to the development of pathology with chronic stress.
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Fujii, Masato, Susumu Ohya, Hisao Yamamura, and Yuji Imaizumi. "Development of Recombinant Cell Line Co-expressing Mutated Nav1.5, Kir2.1, and hERG for the Safety Assay of Drug Candidates." Journal of Biomolecular Screening 17, no. 6 (April 12, 2012): 773–84. http://dx.doi.org/10.1177/1087057112442102.

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To provide a high-throughput screening method for human ether-a-go-go-gene–related gene (hERG) K+ channel inhibition, a new recombinant cell line, in which single action potential (AP)–induced cell death was produced by gene transfection. Mutated human cardiac Na+ channel Nav1.5 (IFM/Q3), which shows extremely slow inactivation, and wild-type inward rectifier K+ channel, Kir2.1, were stably co-expressed in HEK293 cells (IFM/Q3+Kir2.1). In IFM/Q3+Kir2.1, application of single electrical stimulation (ES) elicited a long AP lasting more than 30 s and led cells to die by more than 70%, whereas HEK293 co-transfected with wild-type Nav1.5 and Kir2.1 fully survived. The additional expression of hERG K+ channels in IFM/Q3+Kir2.1 shortened the duration of evoked AP and thereby markedly reduced the cell death. The treatment of the cells with hERG channel inhibitors such as nifekalant, E-4031, cisapride, terfenadine, and verapamil, recovered the prolonged AP and dose-dependently facilitated cell death upon ES. The EC50 values to induce the cell death were 3 µM, 19 nM, 17 nM, 74 nM, and 3 µM, respectively, whereas 10 µM nifedipine did not induce cell death. Results indicate the high utility of this cell system for hERG K+ channel safety assay.
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Miramini, Saeed, Lihai Zhang, Martin Richardson, and Priyan Mendis. "The Role of Locking Plate Stiffness in Bone Fracture Healing Stabilized by Far Cortical Locking Technique." International Journal of Computational Methods 15, no. 04 (May 24, 2018): 1850024. http://dx.doi.org/10.1142/s021987621850024x.

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The locking plate fixations have been developed to enhance bone healing by wide bridging of the fracture and allowing some level of interfragmentary movement (IFM) at the fracture site. However, the IFM induced by conventional locking plate constructs is not uniform at the fracture site and so result in asymmetric callus formation, and ultimately delayed healing. The far cortical locking technique has been recently innovated to address this issue by inducing a uniform IFM. However, the far cortical locking technique is still in its infancy and more research efforts are required before its practical clinical application. Using the theory of porous media and computational methods, this study investigated the effectiveness of far cortical locking technique in presence of different mechanical stiffness of locking plate. The research outcomes indicate that the application of far cortical looking technique enhances IFM at near cortex, and so reduce the difference of IFM between near and far cortex. Further, it shows that, under far cortical locking technique, the bending stiffness of a locking plate plays an important role in bone healing. The use of a stiffer locking plate together with far cortical locking screws encourages more uniform tissue development across the fracture gap. The current research underlines the importance of the optimal selection of plate stiffness for application of far cortical locking technique.
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Neely, Andy. "Cambridge Service Alliance, Distributed Information and Automation Laboratory, Research Capability Development Programme." Global Journal of Enterprise Information System 9, no. 1 (May 5, 2017): 129. http://dx.doi.org/10.18311/gjeis/2017/15879.

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Professor Andy Neely is Pro-Vice-Chancellor: Enterprise and Business Relations at the University of Cambridge, Head of the Institute for Manufacturing (IfM) and Head of the Manufacturing and Management Division of Cambridge University Engineering Department. He is a Fellow of Sidney Sussex College and Founding Director of the Cambridge Service Alliance.
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Hamilton, Colin, Robert Phaal, Mita Brahmbhatt, Peter Jarritt, and Topun Austin. "Designing the landscape for technological development in neonatal neurocritical care." BMJ Innovations 4, no. 4 (August 29, 2018): 163–71. http://dx.doi.org/10.1136/bmjinnov-2018-000288.

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ObjectivesTo identify current ‘gaps’ in clinical practice or therapeutic knowledge of the care of neonatal neurointensive care patients and to determine the impact healthcare technologies can have on improving outcomes.DesignThe Cambridge Institute for Manufacturing’s (IfM) roadmapping methodology.SettingCambridge, UK.Participants16 delegates were selected through professional networks. They provided coverage of academia and clinical skills, as well as expertise in neonatology, engineering and technology development.Main outcome measuresA ‘strategic landscape’ has been developed with ‘landmarks’ identified as ‘trends or drivers’, ‘patient pathway experience and unmet needs’ and ‘enabling project or resources’. Priorities were voted on by delegates.Results26 strategic ‘landmarks’ were identified, and of these 8 were considered ‘trends or drivers’, 8 ‘patient pathway experience and unmet needs’ and 10 as ‘enabling project or resources’. Of these, five priorities for the future of neonatal neurocritical care were identified by a voting process: real-time video monitoring for parents; individualised management of preterm infants in neonatal neurocritical care based on real-time multimodal monitoring; continuous electroencephalogram monitoring for early seizure diagnosis; neuroprotection: understanding basic mechanisms; and sleep measurement.ConclusionsThrough the use of the IfM methodology, a list of priorities has been developed for future work into improving the experience and possible outcomes of newborn infants with brain injuries and their families. While not an exhaustive list, it provides the beginning for a national conversation on the topic.
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Cacheux, W., B. Gourmel, J. Alexandre, N. Germann, F. Rabillon, and F. Goldwasser. "Ifosfamide given once every other week: A clinical and pharmacological study." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 13008. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.13008.

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13008 Background. Ifosfamide (IFM) is a bi-functional alkylator with wide spectrum of activity in solid tumors and has an auto-inductive liver metabolism through P450 cytochromes. Auto-induction might permit a better therapeutic index for combination therapy. Methods. A phase I trial with interpatient dose escalation of a single dose of IFM given every 2 wks in advanced solid tumor pts. IFM, its dechloroethylated and active 4-hydroxy metabolites, were measured at cycle 1 & 2 at the end of infusion, 2 and 5h later, using gas chromatography. IFM elimination was considered as following a monocompartimental model kinetics. Results From January 2004 to June 2006; 20 pts of PS<2 were included :10 F, 10 M, median age 61 years (39–78), median previous chemotherapies: 2 (0–5). Primary tumor was most often ovarian (5), peritoneal (3), sarcoma (2), melanoma (2), or miscellaneous (8). 10 pts received 2.5g/m2 and other 10 pts received 3g/m2. A total of 79 cycles were evaluable for toxicity. median number of cycles: 4 (1–8). No Grade (Gr) 3–4 hematologic toxicity, no alopecia. Gr2 nausea and fatigue were the most common toxicities at 3g/m2. No toxicity-related fatal event was noted. One objective response was noted in pancreatic cancer pt and one sustained CA125 decline in a heavily pretreated ovarian cancer pt. A slight (7–10%) but reproducible decrease of AUC was detectable at cycle 2, at both dose levels, related to auto-inductive metabolism (see table below). The other PK results are available and will be presented (Table). Intra individual variations (large SD) were noticed for each pharmacokinetic (PK) parameter. Conclusions: A slight non dose- dependent but rather patient-dependent auto-induction of IFM metabolism was detected. The toxicity profile allows the development of every 2 wks IFM-based combination therapies. [Table: see text] No significant financial relationships to disclose.
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Trevino-Villarreal, Jose Humberto, Douglas A. Cotanche, Rosalinda Sepulveda, and Rick A. Rogers. "Effect of pericytes on melanoma development." Journal of Clinical Oncology 30, no. 30_suppl (October 20, 2012): 83. http://dx.doi.org/10.1200/jco.2012.30.30_suppl.83.

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83 Background: Melanoma-associated stroma cells regulate tumor establishment, invasion, and dissemination through paracrine and heterotypic cell-cell interactions with cancer cells. Pericytes constitute a major noninflammatory component of the melanoma-associated stroma. Our study is designed to evaluate the role of pericytes in melanoma development. Methods: Tumors induced in GFP+/SCID mice with GFP-B16 cells were harvested after 14 days, enzyme digested, labeled against mesenchymal markers, and analyzed by flow cytometry (FC). The distribution of stromal subpopulations in tumors was investigated by immunofluorescence microscopy (IFM). Stromal pericytes from tumors and adipose tissue were FACS sorted, mixed with B16 cells at a 3:1 ratio, and injected into SCID mice. Tumor diameters were taken periodically with a scientific caliper, and used to determine tumor volumes using the ellipsoid formula. Results: FC analysis showed that the melanoma stroma was composed of CD45+ inflammatory cells, CD31+ endothelial cells, FAP+ myofibroblasts and CD146+ cells. IFM analysis showed that the CD146+ cells are perivascular CD31-/CD34-/α-SMA+ stromal pericytes that associated with TGF-β immunoreactive CD271+/CD146+B16 cells in perivascular tumor niches. Co-induction experiments were performed to investigate the effect of pericytes on melanoma development. We observed faster growth rates in the size of tumors co-induced with pericytes, compared with tumors induced with B16 cells alone. These co-induced tumors had bigger masses, more volume, were hypercellular, and had increase vascularization compared with control tumors. In addition, pericytes increased the B16 cell proliferation rate, as determined by higher expression of Ki-67 in the tumor fraction of co-induced tumors. Conclusions: Pericytes promote melanoma development by inducing angiogenesis and melanoma cell proliferation. Our results suggest that pericytes could be utilized as a therapeutic target for melanoma treatment.
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Fernandes, J., M. Bate, and K. Vijayraghavan. "Development of the indirect flight muscles of Drosophila." Development 113, no. 1 (September 1, 1991): 67–77. http://dx.doi.org/10.1242/dev.113.1.67.

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We have followed the pupal development of the indirect flight muscles (IFMs) of Drosophila melanogaster. At the onset of metamorphosis larval muscles start to histolyze, with the exception of a specific set of thoracic muscles. Myoblasts surround these persisting larval muscles and begin the formation of one group of adult indirect flight muscles, the dorsal longitudinal muscles. We show that the other group of indirect flight muscles, the dorsoventral muscles, develops simultaneously but without the use of larval templates. By morphological criteria and by patterns of specific gene expression, our experiments define events in IFM development.
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Dissertations / Theses on the topic "IFM development"

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Ren, Jun P., Lin Wang, Juan Zhao, Ling Wang, Shun B. Ning, Gazzar Mohamed El, Jonathan P. Moorman, and Zhi Q. Yao. "Decline of miR-124 in Myeloid Cells Promotes Regulatory T-cell Development in Hepatitis C Virus Infection." Digital Commons @ East Tennessee State University, 2016. https://doi.org/10.1111/imm.12680.

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Myeloid‐derived suppressor cells (MDSC s) and microRNA s (miRNA s) contribute to attenuating immune responses during chronic viral infection; however, the precise mechanisms underlying their suppressive activities remain incompletely understood. We have recently shown marked expansion of MDSC s that promote regulatory T (Treg) cell development in patients with chronic hepatitis C virus (HCV ) infection. Here we further investigated whether the HCV ‐induced expansion of MDSC s and Treg cells is regulated by an miRNA ‐mediated mechanism. The RNA array analysis revealed that six miRNA s were up‐regulated and six miRNA s were down‐regulated significantly in myeloid cells during HCV infection. Real‐time RT ‐PCR confirmed the down‐regulation of miR‐124 in MDSC s from HCV patients. Bioinformatic analysis suggested that miR‐124 may be involved in the regulation of signal transducer and activator of transcription 3 (STAT ‐3), which was overexpressed in MDSC s from HCV patients. Notably, silencing of STAT ‐3 significantly increased the miR‐124 expression, whereas reconstituting miR‐124 decreased the levels of STAT ‐3, as well as interleukin‐10 and transforming growth factor‐β , which were overexpressed in MDCS s, and reduced the frequencies of Foxp3+ Treg cells that were developed during chronic HCV infection. These results suggest that reciprocal regulation of miR‐124 and STAT ‐3 in MDSC s promotes Treg cell development, thus uncovering a novel mechanism for the expansion of MDSC and Treg cells during HCV infection.
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Bach, Dang Phong. "Development of a finite element strategy for the modeling of nano-reinforced materials." Thesis, Compiègne, 2020. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2020COMP2550.

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La modélisation des matériaux nano-renforcés nécessite de prendre en compte l’effet de taille induit par les phénomènes locaux à l’interface entre la nanoinclusion et la matrice. Cet effet de taille est interprété par une augmentation du rapport interface/volume et peut être pris en compte en introduisant une élasticité surfacique à l’interface. Alors que de nombreux travaux ont été développés du point de vue analytique, peu de contributions ont trait à la description numérique et à la mise en œuvre de cette élasticité surfacique dans la méthode des éléments finis (FEM). Nos études visent à développer des outils numériques efficaces basés sur la FEM pour la modélisation de nanocomposites. Dans un premier temps, nous évaluons les deux stratégies numériques existantes, à savoir l’approche XFEM et l’approche des éléments d’interface, dans la reproduction de l’effet de taille dans le processus d’homogénéisation. Deuxièmement, sur la base d’un test de performance des trois types de formulations d’E-FEM dans le cas de discontinuités faibles, nous proposons une formulation améliorée de SKON permettant d’intégrer l’effet d’une interface cohérente. Enfin, la modélisation numérique du comportement non linéaire des nanocomposites est étudiée. Lors de la première étape, une loi élastoplastique de type von Mises avec durcissement linéaire isotrope est considérée pour le volume, tandis que l’interface est considérée comme élastique linéaire
The modelization of nano-reinforced material requires to take into account the size effect caused by the local phenomena at the interface between the nano-inclusion and the matrix. This size effect is interpreted through an increase in the ratio interface/volume and can be taken into account by introducing a surface elasticity at the interface. Whereas a lot of works have been developed from the analytical point of view, few contributions are related to numerical description and implementation of such surface elasticity in Finite Element Method (FEM). Our studies aim to develop efficient numerical tools based on FEM for the modeling of nanocomposites. Firstly, we evaluate the two existent numerical strategies namely the XFEM approach and the Interface element approach in reproducing the size effect in the homogenization process. Secondly, based on a performance test on the three types of formulations of E-FEM for the case of weak discontinuity, we propose an enhanced SKON formulation allowing to incorporate the effect of a coherent interface. Finally, the numerical modeling on the nonlinear behavior of nanocomposites is investigated. In the first step, a von Mises type elastoplastic law with linear isotropic hardening is considered for the bulk while the interface is considered as linear elastic
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Jayaraman, Radhakrishnan. "Development of an interactive programming system for IBM 7545 robot." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/90945.

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This thesis presents the development of an interactive programming system for the IBM 7545 robot. Various methods of robot programming are discussed, and the reasons for the development of such an interactive programming system are provided. The development of this system was divided into five phases, namely, the development of the pseudo-compiler, development of the "system control" program, integration of ASSEMBLY routines, development of the "motion control" program, and the development of test programs. The approach used for each of these five stages are outlined, and a reference to the use of the system is given. A description of the development of each stage is then given, and the logic associated with all programs are described, and the purpose and operation of all subroutines are also presented. Some assumptions and limitations of the system are explained, and the operational aspects of the system are described. Additional work needed to improve this system is outlined, and the feasibility of using the concept of this system on other robot programming languages on the IBM 7545 robot are also discussed.
M.S.
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Mohandas, Velluva P. "Development of an interactive graphical simulator for the IBM 7545 robot." Thesis, Virginia Tech, 1987. http://hdl.handle.net/10919/41566.

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In this work an enhanced graphical simulator for the IBM 7545 robot running on the AML/E language was developed. The simulator provided two views with the facility to chose either one as the major view, and pan/zoom into that view. It gives the user the facility to define equipment and workcell setups, accepting data in the Intemational Graphics Exchange Specification (IGES) Version 3.0 format. The user can interactively simulate either the complete program, partial program or any subroutine. The system was integrated including the facility to edit, compile, generate cross references, set system configuration, simulate and run the robot either continuously or interactively.

The system was developed on an IBM Personal Computer using two monitors, text and enhanced graphics for maximizing the display surface for the graphics. The programs developed for this work can be broadly classified into the various menu programs, the definition programs to define and display the equipments and workcells, and the graphic programs for driving and displaying the graphics and altering the views.

The limitations and assumptions made in developing this system along with the scope for further work are presented.


Master of Science
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Wang, Xisheng. "Mechanisms of IFN-gamma-mediated Resistance against Development of Toxoplasmic Encephalitis." Diss., Virginia Tech, 2006. http://hdl.handle.net/10919/30268.

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Toxoplasma gondii, an obligate intracellular protozoan parasite, establishes a latent, chronic infection by forming cysts preferentially in the brain after replication of tachyzoites in various organs during the acute stage of infection. Chronic infection with T. gondii is one of the most common parasitic diseases in humans. The immune system is required for maintaining the latency of chronic infection. Reactivation of infection can occur in immunocompromised individuals, such as AIDS patients, which results in the development of life-threatening toxoplasmic encephalitis (TE). IFN-gamma-dependent, cell mediated immune responses play an essential role in preventing the reactivation of chronic infection of T. gondii in the brain. In my dissertation study, we examined the mechanisms of IFN-gamma-mediated prevention of TE by using models of reactivation of chronic infection in BALB/c mice. This strain of mouse is genetically resistant to T. gondii infection and establishes a latent chronic infection as do immunocompetent humans, and therefore provides an excellet model for this purpose. Our laboratory previously demonstrated that both T cells and IFN-gamma-producing non-T cells are required for genetic resistance of BALB/c mice against development of TE. However, the function of T cells required for the resistance is still unclear. Therefore, in the present study, we examined whether IFN-gamma production or perforin-mediated cytotoxicity of T cells play an important role in their protective activity against TE. Immune T cells were obtained from infected IFN-gamma-knockout (IFN-g-/-), perforin-knockout (PO), and wild-type (WT) BALB/c mice, and transferred into infected, sulfadiazine-treated athymic nude mice which lack T cells but have IFN-gamma-producing non-T cells. Control nude mice that had not received any T cells developed severe TE due to reactivation of infection and died after discontinuation of sulfadiazine treatment. Animals that had received immune T cells from either PO or WT mice did not develop TE and survived. In contrast, nude mice that had received immune T cells from IFN-gamma-/- mice developed severe TE and died as early as control nude mice. T cells obtained from spleens of the animals that had received either PO or WT T cells both produced large amounts of IFN-gamma following stimulation with T. gondii antigens in vitro. In addition, the amounts of IFN-gamma mRNA expressed in the brains of PO T-cell recipients did not differ from those of WT T-cell recipients. These results indicate that IFN-gamma production, but not perforin-mediated cytotoxic activity, by T cells is required for prevention of TE in genetically resistant BALB/c mice. In our attempt to identify a T cell population(s) that produces IFN-gamma in the brain and plays an important role for prevention of TE, we analyzed T cell receptor (TCR) Vb chain usage in T cells expressing IFN-gamma in the brains of infected BALB/c mice. We found T cells bearing TCR V beta8 chain to be the most frequent IFN-g-producing population in the brains of infected animals. To examine the role of IFN-gamma production by this T cell population for prevention of TE, V beta8+ immune T cells purified from spleens of infected BALB/c and IFN-g-/- mice were transferred into infected, sulfadiazine-treated athymic nude mice. After discontinuation of sulfadiazine treatment, control nude mice that had not received any T cells and animals that had received Vb8+ T cells from IFN-g-/- mice all died due to reactivation of infection (TE). In contrast, animals that had received the cells from WT mice survived. These results indicate that IFN-gamma production by Vb8+ T cells in the absence of any other T cell population can prevent reactivation of infection. Thus, V beta8+ T cells play a crucial role in genetic resistance of BALB/c mice to TE through their production of IFN-gamma. When V beta8+ immune T cells were divided into CD4+ and CD8+ subsets, a potent protective activity was observed only in the CD8+ subset whereas a combination of both subsets provided greater protection than did the CD8+Vb8+ population alone. These results indicate that CD8+ subset of V beta8+ T cells is a major afferent limb of IFN-gamma-mediated resistance of BALB/c mice against TE, although the CD4+ subset of the T cell population works additively or synergistically with the CD8+V beta8+ population. T cells need to enter into the brains of infected mice to demonstrate their protective activity against TE. This migration is mediated, in part, by endothelial adhesion molecules. Since IFN-gamma is essential for preventing reactivation of chronic infection with this parasite in the brain, we examined whether this cytokine plays an important role in expression of lymphocyte and endothelial adhesion molecules and recruitment of T cells into the brain during chronic infection with T. gondii using IFN-g-/- and WT BALB/c mice. Although the number of cerebral vessels expressing intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) increased in both WT and IFN-g-/- mice following infection, there were more VCAM-1+ vessels in brains of infected WT than infected IFN-g-/- mice; in contrast, numbers of ICAM-1+ vessels did not differ between strains. We did not detect endothelial E-selectin, P-selectin, MAdCAM-1 or PNAd in any of the brains. Significantly fewer CD8+ T cells were recruited into brains of infected IFN-g-/- than WT mice. Treatment of infected IFN-g-/- mice with recombinant IFN-gamma restored the expression of VCAM-1 on their cerebral vessels and recruitment of CD8+ T cells into their brains, confirming an importance of this cytokine for up-regulation of VCAM-1 expression and CD8+ T cell trafficking. In infected WT and IFN-g-/- animals, almost all cerebral CD8+ T cells had an effector/memory phenotype (LFA-1high, CD44high and CD62Lneg) and approximately 38% were positive for a4b1 integrin (the ligand for VCAM-1). In adoptive transfer of immune spleen cells, pre-treatment of the cells with a monoclonal antibody against a4 integrin markedly inhibited recruitment of CD8+ T cells into the brain of chronically infected wild-type mice. These results indicate that IFN-g-induced expression of endothelial VCAM-1 and its binding to a4b1 integrin on CD8+ T cells is important for recruitment of the T cells into the brain during the chronic stage of T. gondii infection. Since we found strong expression of ICAM-1 on endothelia and LFA-1 on T cells in the brains of infected mice, LFA-1/ICAM-1 interaction, in addition to a4b1 integrin/VCAM-1 interaction, may also be involved in this process. As mentioned earlier, CD8+ T cells are crucial for prevention of TE in BALB/c mice. Therefore, IFN-gamma-mediated expression of VCAM-1 and its binding to a4b1 integrin for recruitment of CD8+ T cells may play a critical role in genetic resistance of BALB/c mice to development of TE.
Ph. D.
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Stewart, Claire Emma. "Viruses and the interferon (IFN) response : methods to improve production and to rapidly select IFN-sensitive viruses for vaccine development." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/11346.

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Manipulation of a virus's capacity to circumvent the interferon (IFN) response aids both fundamental studies as well as many practical applications including the design of live-attenuated vaccines. However, these IFN-sensitive viruses are often difficult to grow to high titer in cells that produce and respond to IFN. In the first part of this study we further characterised the use of the IFN inhibitor, Ruxolitinib (Rux) for its ability to block the IFN response and subsequently enhance replication of IFN-sensitive viruses. This study has shown that i) Rux could provide a more rapid and therefore more efficient alternative for the growth of IFN-sensitive viruses than the current default option, growth in Vero cells and ii) addition of Rux can increase growth of multiple viruses in numerous cell-lines. These results indicate that as well as aiding fundamental studies the addition of Rux could become a valuable technique in a number of virological applications including live attenuated vaccine production and techniques to isolate newly emerging viruses. In the second part of this study we developed a novel method to isolate IFN-sensitive viruses from Paramyxoviruses, using PIV5 (Parainfluenza virus 5) as an experimental model system to obtain selection parameters. We successfully isolated three mutant viruses (rPIV5mCh-α, rPIV5mCh-β and PIV5 W3-γ) that each contain mutations within the IFN antagonist V protein and the P protein which is essential for RNA replication. Subsequently, both rPIV5mCh-α and PIV5 W3-γ were shown to contain non- functional V proteins and exhibit IFN-sensitivity. Ultimately, this study is the first step towards creating a general method to isolate various types of IFN-sensitive viruses that as well as aiding fundamental studies, may be further developed as attenuated vaccines for clinically important viruses lacking vaccines.
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Rajnoch, Adam. "Implementace podpory studia v nástroji IBM Cognos." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-150098.

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In recent years, Business Intelligence is one of the fastest growing software industry according to foreign analyzes. More and more companies realize the importance of tools for Business Intelligence and dashboarding. That is why I chose this topic for my thesis. The main part of this thesis focuses on study support for subject 4IT314 Enterprise Information Systems. This course teaches student how to work with the ERP system Microsoft Dynamics AX. The main shortage of this subject is the lack of feedback to students. Therefore it was decide to integrate BI tools that will be used for dashboarding over database of Microsoft Dynamics AX. In the theoretical part are explains the basic terms essential to understanding BI and dashboarding. On the basis of defined criteria was chose BI tool for integration in to the subject 4IT314. In the practical part of this thesis is described the implementation of this tool and created user documentation, which is used as study materials for students.
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Junior, Claudionei Nalle. "Indicador de Desenvolvimento Municipal (IDM): uma proposta de caracterização dos municípios brasileiros." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/96/96132/tde-30012015-111453/.

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Este trabalho é oriundo da multidisciplinaridade própria das questões de desenvolvimento e da percepção da necessidade de novos elementos e instrumentos de gestão para o gestor público subsidiar a proposição de determinadas ações e políticas. O esforço se concentra no entendimento do fenômeno desenvolvimento e discute a utilização de indicadores na gestão pública. O problema que este projeto discute refere-se a um contexto complexo, e a construção da discussão privilegia a interdisciplinaridade, uma vez que utiliza conceitos oriundos de outras disciplinas como a geografia, a economia, a sociologia, a administração e a ciência política. Nesse sentido, há a clara necessidade de convergência das várias áreas do conhecimento, já que, no ambiente social, coexistem os diversos conceitos. A estrutura do trabalho aborda duas grandes questões - do desenvolvimento e do território - e a relação das duas com um debate de grande importância: a caracterização dos municípios brasileiros enquanto territórios. Desse modo, o objetivo central do trabalho é caracterizar os municípios brasileiros a partir da perspectiva do desenvolvimento. Para tanto, foi construído um banco de dados de abrangência nacional a partir da tabulação e consolidação de diversos dados fornecidos pela Fundação IBGE - Instituto Brasileiro de Geografia e Estatística; INEP - Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira e Ministério da Saúde. Com isso, foi possível a sintetização dos dados e a produção de informações de análise e indicadores de auxílio à caracterização dos municípios brasileiros. Esse corpo de dados permitiu contribuir com a discussão sobre desenvolvimento territorial, suas medidas e usos, bem como compreender a dinâmica das particularidades de territorialidade a partir da qual se constroem as políticas públicas. Além disso, foi possível encontrar, dentre outras observações, uma nova compreensão do fenômeno da ruralidade no Brasil e propor uma nova classificação dos municípios brasileiros em territórios urbanos e rurais.
This thesis arises from the inherent multidisciplinary to development issues and from the perception of the need for new information and management tools to enable public managers when dealing with certain actions and policies. The effort focuses on the understanding of the phenomenon development and discusses the use of indicators in public administration. The problem it proposes refers to a complex context, and its construction emphasizes interdisciplinarity, since it employs concepts and discussions from other disciplines such as Geography, Economics, Sociology, Administration and Political Science. In this sense, there is a clear need for convergence of the various areas of knowledge, once, in the social environment, various concepts coexist. The structure of the paper approaches the understanding of two issues: the development and the territory, and it seeks to understand their relationship with a central debate of great importance, which is the thesis main goal: characterizing Brazilian municipalities as territories from the perspective of development. In order to accomplish it, it was built a nationwide database through the tabulation and consolidation of data provided by IBGE - Brazilian Institute of Geography and Statistics; INEP - National Institute for Educational Studies and Research Anísio Teixeira; and the Ministry of Health. This database allowed contributing to the de discussion of territorial development, its measurement and uses, as well as understanding particular territorial dynamics, which triggers public policies. In addition, among other observations, it was possible to uncover a new view of the rural phenomenon in Brazil and to propose a new classification of Brazilian municipalities either in urban or rural territories.
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Pretorius, Leandri. "The economics of animal welfare: an appraisal of welfare issues ifn the South African poultry industry." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/12191.

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Growing consumer awareness of animal welfare has co-evolved with increases in intensive farming, particularly of battery chickens. This rise in consumer awareness recently saw bans on battery farming in parts of Europe. This thesis addresses the difficulties that would follow any similar attempt to curtail battery farming in South Africa. It examines the literature on animal rights and the welfare issues generated by intensive animal farming, particularly of battery chickens. Thereafter it summarises the findings of surveys into local consumer preferences and retail strategies regarding chicken products.
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Maity, Chaitali. "Determining the role of a candidate gene in Drososphila muscle development." Oxford, Ohio : Miami University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1145459719.

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Books on the topic "IFM development"

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Charles, Hinchey, and Larson James 1947-, eds. DB2 applications development handbook. New York: Intertext Publications, 1989.

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Norman, Geoff. SAA and applications development. Oxford, UK: Elsevier Advanced Technology, 1991.

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Adebowale, Siyanbade. Development of Ife: (1930-1980). [Lagos]: Lichfield Nigeria Ltd., 2000.

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Paul, Yip, ed. Db2 Express: Easy development and administration. Upper Saddle River, N.J: Prentice Hall Professional Technical Reference, 2005.

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Johnson, Brian. IBM UK Limited: A case study in sustainable development. London: UK Centre for Economic and Environmental Development, 1986.

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AD/Cycle: IBM's framework for application development and CASE. New York: Van Nostrand Reinhold, 1991.

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Wiorkowski, Gabrielle. DB2: Design & development guide. 2nd ed. Reading, Mass: Addison-Wesley, 1990.

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David, Kull, ed. DB2: Design & development guide. 3rd ed. Reading, Mass: Addison-Wesley, 1992.

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Wiorkowski, Gabrielle. DB2: Design & development guide. Reading, Mass: Addison-Wesley, 1988.

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Brant, Knudson, and International Business Machines Corporation. International Technical Support Organization, eds. IBM system Blue Gene solution: Blue Gene/P application development. 4th ed. [Poughkeepsie, N.Y.?]: IBM International Technical Support Organization, 2009.

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Book chapters on the topic "IFM development"

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Reed, J. N., J. E. Sinclair, and F. Guigand. "Deductive Reasoning versus Model Checking: Two Formal Approaches for System Development." In IFM’99, 375–94. London: Springer London, 1999. http://dx.doi.org/10.1007/978-1-4471-0851-1_20.

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Boyer, Jérôme, and Hafedh Mili. "IBM WebSphere ILOG JRules." In Agile Business Rule Development, 215–42. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19041-4_8.

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Bluck, Alan S. "IBM Cognos Analytics Custom Development." In IBM Software Systems Integration, 903–90. Berkeley, CA: Apress, 2023. http://dx.doi.org/10.1007/978-1-4842-8861-0_5.

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Hansen, John Erik, and Carsten Thomsen. "IBM Rational XDE." In Enterprise Development with Visual Studio .NET, UML, and MSF, 791–811. Berkeley, CA: Apress, 2004. http://dx.doi.org/10.1007/978-1-4302-0696-5_18.

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Bluck, Alan S. "IBM JMS Interface Development IBM FileNet 5.5.x Workflow." In IBM Software Systems Integration, 335–646. Berkeley, CA: Apress, 2023. http://dx.doi.org/10.1007/978-1-4842-8861-0_3.

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van der Zweerde, Evert. "The Development of IFN (1920s–1980s)." In Sovietica, 59–91. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-015-8943-7_3.

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Lucena, Percival, Alan Braz, Adilson Chicoria, and Leonardo Tizzei. "IBM Design Thinking Software Development Framework." In Agile Methods, 98–109. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-55907-0_9.

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Roux, Manfred, and Oliver Gassmann. "IBM: Using Global Networks for Virtual Development." In Managing Global Innovation, 381–94. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-03895-6_20.

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Schröder, Beer R. E. V. M. "IFP from a Comparative International Development Perspective." In Leadership for Social Justice in Higher Education, 35–46. New York: Palgrave Macmillan US, 2014. http://dx.doi.org/10.1057/9781137361455_3.

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Schaffers, Kathleen, Andrew J. Bayramian, Joseph A. Menapace, Gregory T. Rogowski, Thomas F. Soules, Christopher A. Stolz, Steve B. Sutton, et al. "Advanced Material Development for Inertial Fusion Energy (IFE)." In Crystal Growth Technology, 229–48. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527632879.ch13.

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Conference papers on the topic "IFM development"

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Sadek, Tim, Michael Wendland, and Daniel Meuris. "Heterogeneous Modeling as a Basis for Improving the Reliability of Product Concepts." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62086.

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The importance of the early design stages in a new product development for a successful outcome is well known. Reliability is a key property that can be identified as a major success factor for customer satisfaction. Therefore, it is necessary to ensure a reliability-oriented design process. Regarding the early design phases, several problems are identified in this paper. Insufficient methodical support, as well as a lack of knowledge and high uncertainty due to the use of new technologies, form major barriers for designers to create reliable products. This paper describes a combined modeling approach for reducing uncertainty and identifying potential failure modes in early design phases. Based upon “heterogeneous concept modeling” (HCM), a new method called “inverse functional modeling” (IFM) for identifying non-intended functions and non-intended physical effects is introduced. This novel approach is then evaluated by analyzing the reliability of an actuator based upon shape memory alloy, which represents a new technology inducing uncertainty. In addition, a computer-based tool is developed to allow the practical application of the described modeling approach and further aid the designer in creating reliable products.
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DENT, HAMRUD, MOZDZYNSKI, SALMOND, and TEMPERTON. "IFS DEVELOPMENTS." In Proceedings of the Ninth ECMWF Workshop on the Use of High Performance Computing in Meteorology. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812799685_0004.

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Xu, Yiban, Michael A. Krammen, Guoqiang Wang, Jesse S. Fisher, and Zeses Karoutas. "Analysis of Particle Transfer Behavior in Fuel Rod Bundles Using CFD Lagrangian Particle Tracking Method." In 2021 28th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/icone28-66793.

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Abstract Crud has been observed on the fuel rod surfaces in a variety of fuel designs around the world, and in some limited situations fuel performance was compromised due to crud-induced power shift (CIPS) and/or crud-induced localized corrosion (CILC). It is generally believed that crud deposition depends on fuel rod surface sub-cooled nucleate boiling, coolant chemistry and the availability of particles from component corrosion or from reinserted fuel. The formation, release, and accumulation of crud on the fuel and its influence on CIPS and/or CILC is a complicated process involving multi-physics phenomena. This study uses Computational Fluid Dynamics (CFD) Lagrangian Particle Tracking (LPT) techniques in analysis of particle transfer behavior in fuel rod bundles focusing on flow swirl and turbulence impacts. It is hoped that high fidelity CFD results can provide insights into particle transfer behaviors in the bulk coolant as well as near the fuel rods, which may provide guidance for model development of lumped or integrated analysis methods. The CFD model was built based on the best practices learned from previous single-phase analyses. The LPT options, including particle injectors, forces on particles, and solver settings, were verified by comparing the simulated results to the test data from simple geometry with various particle sizes, covering deposition mechanisms in diffusion-, turbulent- and inertial-dominated regimes. The tested model then was applied to Westinghouse fuel designs with and without Intermediate Flow Mixing (IFM) grids. Particle concentration and size distributions in the coolant around fuel rods were obtained and the effects of grid induced swirl flow on particle transfer were identified. The analysis results may be included in lumped or integrated crud formation/release analysis methods. Limitations and potential improvements of this analysis method are also discussed.
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Maximilien, E. M., and L. Williams. "Assessing test-driven development at IBM." In 25th International Conference on Software Engineering, 2003. Proceedings. IEEE, 2003. http://dx.doi.org/10.1109/icse.2003.1201238.

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Araujo, Rodrigo Fraxino, Daniel Henrique Barboza, Otavio Busatto Pontes, Rafael Medeiros Teixeira, Renato Stoffalette Joao, Wainer Santos Moschetta, and Vinicius H. S. Durelli. "IBM Software Development Kit for PowerLinux." In 2012 2nd Workshop on Developing Tools as Plug-ins (TOPI). IEEE, 2012. http://dx.doi.org/10.1109/topi.2012.6229818.

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Stone, S. H., and E. S. Girbovan. "Development of Optical Disk Architecture." In Optical Data Storage. Washington, D.C.: Optica Publishing Group, 1985. http://dx.doi.org/10.1364/ods.1985.thdd4.

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Magnetic data disks have been widely in use in computer systems since the 1960s. During this period, the disks have become smaller is size as the density of the data on the media has increased. During the last 25 years the data density has increased from 2,000 bits per square inch (IBM 350) to an estimated 24 million bits per square inch on the recently announced models of the IBM 3380.
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Stokmane, Maija, Anita Lontone-Ievina, and Raimonds Ernsteins. "Municipal integrated coastal governance approach: complimentary disciplinary instruments and collaboration pre-conditions." In 22nd International Scientific Conference. “Economic Science for Rural Development 2021”. Latvia University of Life Sciences and Technologies. Faculty of Economics and Social Development, 2021. http://dx.doi.org/10.22616/esrd.2021.55.022.

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Municipal coastal governance practice also in Latvia has various limitations, and taking into account growing climate change adaptation challenges, new understanding and new approaches are to be studied and tested. Overall study frame is based on research-and-development approach. The aim of the research was to study how municipal coastal governance is functioning in practice, particularly, in the relation to the coastal dune protection zones (150/300 m) and further coastal territory behind that, applying whole list of governance instrument groups – political/legal, planning, and especially institutional instruments, also financial, infrastructure and, last but not least, coastal communication instruments. This was done via research-and-governance frame of the three coastal governance dimensions – governance content, stakeholders (governance segments) and governance instruments, realized in Jurmala municipality as especially nature-culture rich and due to tourist attraction also sensitive coastal pilot territory at the Latvia coast. Case study research methodology applied (document studies, observation and stakeholder’s interviews) were approving pre-study understanding, based on previous coastal governance studies, that also this territory with international coastal resort status and well developed municipal administration capacities have limited success on integrated coastal management (ICM) approach implementation and, subsequently, there are requirements on further development of disciplinary instruments and also collaboration governance as ICM preconditions. An integrated ICM approach was internationally designed and approved also for EU coastal countries, since comprehensive requirement to manage the adequate governance of the coast as complex socio-ecological system, but old shaped long existing traditional disciplinary/branch approaches of former and formal municipal planning and management does not really permit necessary innovations with cross-sectorial and cross-level integration perspectives. However, also orientation towards re-use and/or re-development of disciplinary ICM instruments, especially, to be designed and realized as complementary as possible and collaboration governance developments shall be seen as necessary pre-conditions for ICM adequate development.
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Yamada, Katsumi, Abdallah Amri, Lyndon Bevington, and Pal Vincze. "Post-Fukushima Research and Development Strategies and Priorities for Water Cooled Reactor Technology Development." In 2016 24th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/icone24-60877.

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The Great East Japan Earthquake and the subsequent tsunami on 11 March 2011 initiated accident conditions at several nuclear power plants (NPPs) on the north-east coast of Japan and developed into a severe accident at the Fukushima Daiichi NPP, which highlighted a number of nuclear safety issues. After the Fukushima Daiichi accident, new research and development (R&D) activities have been undertaken by many countries and international organizations relating to severe accidents at NPPs. The IAEA held, in cooperation with the OECD/NEA, the International Experts’ Meeting (IEM) on “Strengthening Research and Development Effectiveness in the Light of the Accident at the Fukushima Daiichi Nuclear Power Plant” at IAEA Headquarters in Vienna, Austria, 16–20 February 2015. The objective of the IEM was to facilitate the exchange of information on these R&D activities and to further strengthen international collaboration among Member States and international organizations. One of the main conclusions of the IEM was that the Fukushima Daiichi accident had not identified completely new phenomena to be addressed, but that the existing strategies and priorities for R&D should be reconsidered. Significant R&D activities had been already performed regarding severe accidents of water cooled reactors (WCRs) before the accident, and the information was very useful for predicting and understanding the accident progression. However, the Fukushima Daiichi accident highlighted several challenges that should be addressed by reconsidering R&D strategies and priorities. Following this IEM, the IAEA invited several consultants to IAEA Headquarters, Vienna, Austria, 12–14 May 2015, and held a meeting in order to discuss proposals on possible IAEA activities to facilitate international R&D collaboration in relation to severe accidents and how to effectively disseminate the information obtained at the IEM. The IAEA also held Technical Meeting (TM) on “Post-Fukushima Research and Development Strategies and Priorities” at IAEA Headquarters, Vienna, Austria, 15–18 December 2015. The objective of this meeting was to provide a platform for experts from Member States and international organizations to exchange perspectives and information on strategies and priorities for R&D regarding the Fukushima Daiichi accident and severe accidents in general. The experts discussed R&D topic areas that need further attention and the benefits of possible international cooperation. This paper discusses lessons learned from the Fukushima Daiichi accident based on the presentations and discussions at the meetings mentioned above, and identifies the needs for further R&D activities to develop WCR technologies to cope with Fukushima Daiichi-type accidents.
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Sheinis, A., L. Cowie, and D. McKenna. "MicroThermal Instrumentation for Haleakala Site Survey Development and Implementation." In Adaptive Optics for Large Telescopes. Washington, D.C.: Optica Publishing Group, 1992. http://dx.doi.org/10.1364/aolt.1992.amb3.

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The University of Hawaii (UH) Institute for Astronomy (IFA) has undergone a microthermal characterization exercise of the summit of Mt. Haleakala, Maui Hawaii. Instrumentation specific to this characterization has been developed jointly by the UH School for Ocean and Earth Science (SOEST) and the UH IFA. This paper details the instrumentation (development and characterization), discusses the specific data acquisition and reduction techniques, and gives the preliminary results of the survey.
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Breitenbach, Andrea. "THE INVERTED CLASSROOM MODEL (ICM) - A MODEL FOR DIFFERENT SEMINAR TYPES." In 12th International Technology, Education and Development Conference. IATED, 2018. http://dx.doi.org/10.21125/inted.2018.0422.

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Reports on the topic "IFM development"

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Bacon, Diana. NRAP-Open-IAM: Generic Aquifer Component Development and Testing. Office of Scientific and Technical Information (OSTI), February 2022. http://dx.doi.org/10.2172/1845855.

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Baek, Seunghwan, Diana Bacon, and Nicolas Huerta. NRAP-Open-IAM Analytical Reservoir Model - Development and Testing. Office of Scientific and Technical Information (OSTI), June 2021. http://dx.doi.org/10.2172/1855765.

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Robin E. Richards, Ph D. DEVELOPMENT OF ITM OXYGEN TECHNOLOGY FOR INTEGRATION IN IGCC & OTHER ADVANCED POWER GENERATION SYSTEMS (ITM OXYGEN). Office of Scientific and Technical Information (OSTI), April 2001. http://dx.doi.org/10.2172/808545.

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Robin E. Richards, Ph D. DEVELOPMENT OF ITM OXYGEN TECHNOLOGY FOR INTEGRATION IN IGCC & OTHER ADVANCED POWER GENERATION SYSTEMS (ITM OXYGEN). Office of Scientific and Technical Information (OSTI), May 2001. http://dx.doi.org/10.2172/808548.

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Robin E. Richards, Ph D. DEVELOPMENT OF ITM OXYGEN TECHNOLOGY FOR INTEGRATION IN IGCC & OTHER ADVANCED POWER GENERATION SYSTEMS (ITM OXYGEN). Office of Scientific and Technical Information (OSTI), June 2001. http://dx.doi.org/10.2172/808549.

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Tolkach, V., V. Morozov, and A. Hassanein. Development of comprehensive models for opacities and radiation transport for IFE systems. Office of Scientific and Technical Information (OSTI), June 2003. http://dx.doi.org/10.2172/820525.

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Braden, Robert T. Continued Development of Internet Protocols under the IBM OS/MVS operating System. Fort Belvoir, VA: Defense Technical Information Center, March 1986. http://dx.doi.org/10.21236/ada167055.

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Braden, Robert T. Continued Development of Internet Protocols under the IBM OS/MVS Operating System. Fort Belvoir, VA: Defense Technical Information Center, January 1985. http://dx.doi.org/10.21236/ada167180.

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Bibeau, C., K. Schaffers, J. Tassano, P. Waide, and A. Bayramian. FY00 LDRD Final Report High Power IFE Driver Component Development 00-SI-009. Office of Scientific and Technical Information (OSTI), February 2001. http://dx.doi.org/10.2172/15013545.

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Armstrong, Phillip A. Development of ITM oxygen technology for integration in IGCC and other advanced power generation. Office of Scientific and Technical Information (OSTI), March 2015. http://dx.doi.org/10.2172/1224800.

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