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1

Kogan, Mykhailo, Oleg Zadorozhnyy, Andrii Korol, Oksana Petretskaya, Tatiana Krasnovid, and Nataliya Pasyechnikova. "Visualisierung von intraokularen Fremdkörpern im Ziliarkörperbereich mittels infraroter Transillumination (Pilotstudie)." Klinische Monatsblätter für Augenheilkunde 237, no. 07 (May 20, 2020): 889–93. http://dx.doi.org/10.1055/a-1142-6502.

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Zusammenfassung Hintergrund Trotz der Verbesserung der Diagnosetechnologien bleibt die Detektion von intraokularen Fremdkörpern (IFK), die sich in der Projektion des Ziliarkörpers befinden, eines der aktuellen Probleme der Augentraumatologie. Ziel Untersuchung der möglichen Visualisierung intraokularer Fremdkörper (IFK) in der Projektion des Ziliarkörpers mithilfe der infrarоten transpalpebralen Transillumination (IRTT). Materialien und Methoden Analyse von 10 Personen (10 Augen) mit einer penetrierenden Augenwunde und nachgewiesenem IFK. In allen Fällen erfolgten Röntgendiagnostik, Ultraschalluntersuchung des Auges und IRTT. Ergebnisse Bei allen Patienten wurden Schatten von den Strukturen des Ziliarkörpers (Pars plana, Pars plicata) auf der Sklera mittels IRTT und Schatten von IFK visualisiert. Schlussfolgerung Die Technik der IRTT bei Patienten mit penetrierenden Augenverletzungen ermöglicht die nicht invasive Visualisierung von IFK in der Projektion des Ziliarkörpers und die Identifizierung ihrer Lokalisation.
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2

Trocha, Marcus. "IFK-Wissenschaftspreis für Camilla Kapitza." manuelletherapie 17, no. 04 (September 19, 2013): 148. http://dx.doi.org/10.1055/s-0033-1356784.

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3

Haarer-Becker, Rosi. "IFK-Fachkongress – Direktzugang: Nur eine Frage der Zeit." physiopraxis 9, no. 11/12 (November 2011): 15. http://dx.doi.org/10.1055/s-0031-1298036.

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4

Baštinec, Jaromír, and Josef Diblík. "Subdominant positive solutions of the discrete equationΔu(k+n)=−p(k)u(k)." Abstract and Applied Analysis 2004, no. 6 (2004): 461–70. http://dx.doi.org/10.1155/s1085337504306056.

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A delayed discrete equationΔu(k+n)=−p(k)u(k)with positive coefficientpis considered. Sufficient conditions with respect topare formulated in order to guarantee the existence of positive solutions ifk→∞. As a tool of the proof of corresponding result, the method described in the author's previous papers is used. Except for the fact of the existence of positive solutions, their upper estimation is given. The analysis shows that every positive solution of the indicated family of positive solutions tends to zero (ifk→∞) with the speednot smaller than the speed characterized by the functionk·(n/(n+1))k. A comparison with the known results is given and some open questions are discussed.
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5

Omodara, T. R., and Esther Y. Aderibigbe. "Microbiological, Physicochemical and Enzymatic Changes in Fermented African Locust Bean (Parkia biglobosa) Seeds Using Bacillus subtilis and Additives." Sustainable Food Production 1 (March 2018): 22–29. http://dx.doi.org/10.18052/www.scipress.com/sfp.1.22.

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Traditional fermentation of dried seeds ofParkia biglobosais used to produce a local product called ‘iru’. It is a condiment consumed mostly in Western Nigeria. In this study, the effect ofBacillussubtilisBC4333starter cultures and different additives, such as local softening agents called ‘kuuru’,Hibiscus sabdariffaseed cotyledon and ash from cashew (Anacardium occidentals) plants as on the microbiological, physicochemical, and enzymatic properties of fermentedParkia biglobosaseeds were investigated. The dried seeds ofParkia biglobosawere processed by boiling the cotyledons withHibiscus sabdariffa,‘kuuru’ andAnacardium occidentals(cashew plant) ash using natural fermentation andBacillus subtilisstrainBC4333as a starter culture. The fermentations were carried out at 35°C for 36 hrs. Commercially fermented Parkiabiglobosaseed (called ‘iru-pete’) was used as control. All the samples were analyzed for microbial, physico-chemical and enzymatic properties using standard biochemical techniques. ‘Iru’ produced using ‘kuuru’ (IFK) had the highest microbial count of 7.88 log CFU/g, while the microbial count of íru’ produced with ash (IFA) and íru’ produced with dried seeds ofHibscus sabdariffa(IFH) were 7.69 log CFU/g and 7.75 log CFU/g respectively. The pH of the fermented products ranged between 7.06 and 7.91, while the unfermented sample (UFS) had pH 6.68. The unfermented sample had the highest total titratable acidity (TTA) of 2.6×10-2N while the ‘iru’ samples produced using ‘kuuru’(IFK) had the least TTA of 1.0×10-2N. Fermentation significantly increased the moisture content of the products. Starter culture fermented ‘iru’ (F14) had the highest protease, amylase and phytase activity of 232.3UPR, 0.41UAM and 71.85UPH respectively. Findings from this study suggest that ‘iru’ produced by addition ofBacillus subtilisstrain BC4333 had the best desirable biochemical qualities when compared to the other test additives and thus recommened for commercial scale.
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6

Martin, Ursula, and Elizabeth Scott. "The order types of termination orderings on monadic terms, strings and multisets." Journal of Symbolic Logic 62, no. 2 (June 1997): 624–35. http://dx.doi.org/10.2307/2275551.

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AbstractWe consider total well-founded orderings on monadic terms satisfying the replacement and full invariance properties. We show that any such ordering on monadic terms in one variable and two unary function symbols must have order typeω,ω2orωω. We show that a familiar construction gives rise to continuum many such orderings of order typeω. We construct a new family of such orderings of order typeω2, and show that there are continuum many of these. We show that there are only four such orderings of order typeωω, the two familiar recursive path orderings and two closely related orderings. We consider also total well-founded orderings onNnwhich are preserved under vector addition. We show that any such ordering must have order typeωkfor some 1 ≤k≤n. We show that ifk<nthere are continuum many such orderings, and ifk=nthere are onlyn!, then! lexicographic orderings.
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7

Merz, Ute. "Mit Berufsverbänden im Gespräch." physiopraxis 6, no. 11/12 (November 2008): 12–14. http://dx.doi.org/10.1055/s-0032-1308163.

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Seit Juli 2008 gibt es mehr gesetzlich zugesicherte Mitwirkungsrechte für Physiotherapeuten bei der Patientenversorgung. Im Interview mit physiopraxis sprechen die Vorsitzende des IFK, Ute Repschläger, und die Vorsitzende vom ZVK, Ulrike Steinecke, über den aktuellen Stand der Modellvorhaben für Physiotherapeuten.
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8

Veit, Katrin. "Testbatterie bei unspezifischem Rückenschmerz – Wissenschaft nachgefragt." physiopraxis 18, no. 05 (May 2020): 14–15. http://dx.doi.org/10.1055/a-1137-0634.

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Christoph Biele untersuchte in seiner Masterarbeit, ob es sinnvoll ist, die Testbatterie von Hannu Luomajoki zur motorischen Kontrolle bei unspezifischen Rückenschmerzen zu erweitern. Mit seiner Arbeit gewann er den IFK-Wissenschaftspreis 2019 und publizierte sie international im British Medical Journal.
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9

Lummer, Stefan. "Die Gesundheitsreform krankt." physiopraxis 4, no. 10 (October 2006): 12–16. http://dx.doi.org/10.1055/s-0032-1307971.

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Die Eckpunkte der Gesundheitsreform stoßen auf harsche Kritik. Verstaatlichung des Systems, Unterdrückung des Wettbewerbs und keine Lösung des Finanzierungsproblems, das war der Tenor des Treffens der AG Zukunft des Gesundheitswesens, das anlässlich des 25-jährigen Jubiläums des Berufsverbands IFK in Bochum stattfand.
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10

Cho, Chong-Man. "Spaces of compact operators which areM-ideals inL(X,Y)." International Journal of Mathematics and Mathematical Sciences 15, no. 3 (1992): 617–19. http://dx.doi.org/10.1155/s0161171292000802.

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SupposeXandYare reflexive Banach spaces. IfK(X,Y), the space of all compact linear operaters fromXtoYis anM-ideal inL(X,Y), the space of all bounded linear operators fromXtoY, then the second dual spaceK(X,Y)**ofK(X,Y)is isometrically isomorphic toL(X,Y).
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11

Oldenburg, Elke. "IFK-Modellvorhaben für mehr Autonomie – Die Zeit für Modellvorhaben zum Direktzugang ist reif!" physiopraxis 16, no. 05 (May 2018): 10–12. http://dx.doi.org/10.1055/s-0043-124921.

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Es gibt Krankenkassen, die ein großes Interesse daran haben, dass ihre Versicherten bei bestimmten Erkrankungen direkt zum Physiotherapeuten gehen können und nicht den Umweg über den Arzt nehmen müssen. Eine davon ist die BIG direkt gesund. Sie und der Berufsverband IFK haben jüngst in einem Modellvorhaben belegt: Physiotherapeuten gehen verantwortlich mit Entscheidungsfreiheit um.
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12

Baumann, Elke. "IFK-Modellversuch für Mehr Autonomie - „Wir sind bereit für den Direktzugang“." physiopraxis 9, no. 05 (May 2011): 10–11. http://dx.doi.org/10.1055/s-0031-1280574.

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13

DUDEK, ANDRZEJ, ALAN FRIEZE, ANDRZEJ RUCIŃSKI, and MATAS ŠILEIKIS. "Loose Hamilton Cycles in Regular Hypergraphs." Combinatorics, Probability and Computing 24, no. 1 (September 24, 2014): 179–94. http://dx.doi.org/10.1017/s0963548314000406.

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We establish a relation between two uniform models of randomk-graphs (for constantk⩾ 3) onnlabelled vertices: ℍ(k)(n,m), the randomk-graph with exactlymedges, and ℍ(k)(n,d), the randomd-regulark-graph. By extending the switching technique of McKay and Wormald tok-graphs, we show that, for some range ofd = d(n)and a constantc> 0, ifm~cnd, then one can couple ℍ(k)(n,m)and ℍ(k)(n,d)so that the latter contains the former with probability tending to one asn→ ∞. In view of known results on the existence of a loose Hamilton cycle in ℍ(k)(n,m), we conclude that ℍ(k)(n,d)contains a loose Hamilton cycle whend≫ logn(or justd⩾Clogn, ifk= 3) andd=o(n1/2).
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14

BUGEAUD, YANN, ANDREJ DUJELLA, and MAURICE MIGNOTTE. "ON THE FAMILY OF DIOPHANTINE TRIPLES {k− 1,k+ 1, 16k3− 4k}." Glasgow Mathematical Journal 49, no. 2 (May 2007): 333–44. http://dx.doi.org/10.1017/s0017089507003564.

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AbstractIt is proven that ifk≥ 2 is an integer anddis a positive integer such that the product of any two distinct elements of the setincreased by 1 is a perfect square, thend= 4kord= 64k5−48k3+8k. Together with a recent result of Fujita, this shows that all Diophantine quadruples of the form {k− 1,k+ 1,c,d} are regular.
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15

Awass, Omer. "Authenticating the Sīrah Literature: A Case Study of Ibn Isḥāq’s Ifk Report." Muslim World 109, no. 3 (July 2019): 327–42. http://dx.doi.org/10.1111/muwo.12304.

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16

SMEETS, ARNE. "Principes locaux-globaux pour certaines fibrations en torseurs sous un tore." Mathematical Proceedings of the Cambridge Philosophical Society 158, no. 1 (December 8, 2014): 131–45. http://dx.doi.org/10.1017/s0305004114000577.

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AbstractLetkbe a number field andTak-torus. Consider a family of torsors underT, i.e. a morphismf:X→ ℙ1kfrom a projective, smoothk-varietyXto ℙ1k, the generic fibreXη→ η of which is a smooth compactification of a principal homogeneous space underT⊗kη. We study the Brauer–Manin obstruction to the Hasse principle and to weak approximation forX, assuming Schinzel's hypothesis. We generalise Wei's recent results [21]. Our results are unconditional ifk=Qand all non-split fibres offare defined overQ. We also establish an unconditional analogue of our main result for zero-cycles of degree 1.
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17

Walker, P. M., G. D. Dracoulis, A. P. Byrne, B. Fabricius, T. Kibedi, A. E. Stuchbery, and N. Rowley. "Multi-quasiparticle and rotational structures in 179W: Fermi alignment, the ifK-selection rule and blocking." Nuclear Physics A 568, no. 2 (February 1994): 397–444. http://dx.doi.org/10.1016/0375-9474(94)90209-7.

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18

Crestani, Eleonora, Giovanni De Franceschi, and Andrea Lucchini. "Probability and Bias in Generating Supersoluble Groups." Proceedings of the Edinburgh Mathematical Society 59, no. 4 (December 22, 2015): 899–909. http://dx.doi.org/10.1017/s0013091515000504.

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AbstractWe discuss some questions related to the generation of supersoluble groups. First we prove that the number of elements needed to generate a finite supersoluble groupGwith good probability can be quite a lot larger than the smallest cardinality d(G) of a generating set ofG. Indeed, ifGis the free prosupersoluble group of rankd⩾ 2 and dP(G) is the minimum integerksuch that the probability of generatingGwithkelements is positive, then dP(G) = 2d+ 1. In contrast to this, ifk–d(G) ⩾ 3, then the distribution of the first component in ak-tuple chosen uniformly in the set of all thek-tuples generatingGis not too far from the uniform distribution.
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19

Wilkins, Dave. "The strongWCDproperty for Banach spaces." International Journal of Mathematics and Mathematical Sciences 18, no. 1 (1995): 67–70. http://dx.doi.org/10.1155/s0161171295000081.

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In this paper, we introduce weakly compact version of the weakly countably determined (WCD) property, the strongWCD(SWCD) property. A Banach spaceXis said to beSWCDif there s a sequence (An) of weak∗compact subsets ofX∗∗such that ifK⊂Xis weakly compact, there is an(nm)⊂Nsuch thatK⊂⋂m=1∞Anm⊂X. In this case, (An) is called a strongly determining sequence forX. We show thatSWCG⇒SWCDand that the converse does not hold in general. In fact,Xis a separableSWCDspace if and only if (X, weak) is anℵ0-space. Usingc0for an example, we show how weakly compact structure theorems may be used to construct strongly determining sequences.
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20

Moch Arifin. "PANDANGAN AL-QUR`AN DALAM MERESPONS FENOMENA HOAX." AL ITQAN: Jurnal Studi Al-Qur'an 4, no. 1 (February 20, 2016): 91–111. http://dx.doi.org/10.47454/itqan.v4i1.681.

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Abstract One of the social problems in the world, especially in Indonesia today, is the prevalence of hoax reported in various mass media. The emergence of this news not only confuses various levels of society, but even defames the reputation of certain parties. This article aims to explain how the view of the Qur'an in responding to the hoax phenomenon. By using the thematic interpretation approach initiated by al-Farmāwī, the author aims to describe the verses of the al-Qur`an which are related to the issue of news and the story of ḥadīts al-ifk that afflicted 'Āisyah. Key words;hoax, thematic interpretation, verses of the Qur'an.
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Hou, Hailong, Rui Gu, and Mengdi Tong. "Pretty good state transfer on 1-sum of star graphs." Open Mathematics 16, no. 1 (December 27, 2018): 1483–89. http://dx.doi.org/10.1515/math-2018-0119.

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AbstractLetAbe the adjacency matrix of a graphGand supposeU(t) = exp(itA). We say that we have perfect state transfer inGfrom the vertexuto the vertexvat timetif there is a scalarγof unit modulus such thatU(t)eu=γ ev. It is known that perfect state transfer is rare. So C.Godsil gave a relaxation of this definition: we say that we have pretty good state transfer fromutovif there exists a complex numberγof unit modulus and, for each positive realϵthere is a timetsuch that ‖U(t)eu–γ ev‖ <ϵ. In this paper, the quantum state transfer on 1-sum of star graphsFk,lis explored. We show that there is no perfect state transfer onFk,l, but there is pretty good state transfer onFk,lif and only ifk=l.
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22

Abdul-Ghafour, Abdul-Qader Khaleel Mohammed, Yasser Alrefaee, Sameer Boset, and Morshed S. Al-Jaro. "Investigating the meaning of Al-'ifk and Al-kadhib (Lie) and their English Translation by Abdullah Yusuf Ali." ELS Journal on Interdisciplinary Studies in Humanities 2, no. 2 (June 30, 2019): 182–92. http://dx.doi.org/10.34050/els-jish.v2i2.6304.

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This study investigates the meaning of the Qur'ānic near-synonyms الإفك al-'ifk and الكذب al-kadhib (lie) and their English translation. It aims to identify the contextual meaning of these Qur'ānic near-synonyms based on the exegeses of the Holy Qur'ān. Then, it explains the nuances that exist between these two lexical items in terms of denotative meaning. This study also examines how the semantic differences between these Qur'ānic near-synonyms are reflected in the English translation of the Holy Qur'ān by Ali (2006). This study adopts the RC-S approach by Murphy (2003) as a theoretical framework for data analysis. It also employs the qualitative approach to collect and analyze the data of the study. The exegeses of the Holy Qur'ān are consulted to identify the semantic differences between the Qur'ānic near-synonyms. The findings reveal that there exist some differences in meaning between these Qur'ānic near-synonyms in terms of denotative meaning and that the semantic differences between these Qur'ānic near-synonyms are not reflected in Ali's English translation of the Holy Qur'ān. The study provides recommendations for readers and translators especially the translators of the Holy Qur'ān.
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23

Heine, M. "Modellvorhaben BIG direkt gesund und IFK e.V.: Welche Heilmittel wählen Physiotherapeuten bei Unabhängigkeit von der ärztlichen Verordnung? 1." Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin 28, no. 04 (August 2018): 243. http://dx.doi.org/10.1055/s-0038-1668270.

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24

Dieter, Heiko, Ajay R. Bidwe, Glykeria Varela-Duelli, Alexander Charitos, Craig Hawthorne, and Günter Scheffknecht. "Development of the calcium looping CO2 capture technology from lab to pilot scale at IFK, University of Stuttgart." Fuel 127 (July 2014): 23–37. http://dx.doi.org/10.1016/j.fuel.2014.01.063.

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25

Mahanti, Mina Ketan, Amandeep Singh, and Lokanath Sahoo. "Real Zeros of a Class of Hyperbolic Polynomials with Random Coefficients." International Journal of Mathematics and Mathematical Sciences 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/261370.

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We have proved here that the expected number of real zeros of a random hyperbolic polynomial of the formy=Pnt=n1a1cosh⁡t+n2a2cosh⁡2t+⋯+nnancosh⁡nt, wherea1,…,anis a sequence of standard Gaussian random variables, isn/2+op(1). It is shown that the asymptotic value of expected number of times the polynomial crosses the levely=Kis alson/2as long asKdoes not exceed2neμ(n), whereμ(n)=o(n). The number of oscillations ofPn(t)abouty=Kwill be less thann/2asymptotically only ifK=2neμ(n), whereμ(n)=O(n)orn-1μ(n)→∞. In the former case the number of oscillations continues to be a fraction ofnand decreases with the increase in value ofμ(n). In the latter case, the number of oscillations reduces toop(n)and almost no trace of the curve is expected to be present above the levely=Kifμ(n)/(nlogn)→∞.
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M., Hasbi, Hasbullah Hasbullah, and Jamaluddin Jamaluddin. "The Motive Of Wearing A Face Veil In The Early Islam: Two Narratives Of Prophetic Traditions." Mutawatir : Jurnal Keilmuan Tafsir Hadith 8, no. 2 (December 21, 2018): 254–74. http://dx.doi.org/10.15642/mutawatir.2018.8.2.254-274.

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This article discusses the motives for wearing a face veil in early Islam. With the lens of prophetic historical reflection, it focuses on two narratives of the hadith on veil: the Arab women who sold in the market of Bani Qaynuqa‘ and ‘Aishah on hadith al-ifk. This article argues that the motives of covering their faces has close related to the situation and conditions occurred at the time. Historically, the two stories explained that wearing a face veil as a protection of dignity and self-esteem from an uncomfortable milieu. Sociologically, the face veil was cultural habits in guarding women from any social disorders and negative treatment. While psychologically, wearing a face veil symbolized the purity of an honor and the high value of personality embedded in the dignity of women so as not to invite a slander.
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Wirdiyana, Salwa Sofia. "HOAKS DAN ALQURAN: UPAYA MEMBANGUN PERADABAN KRITIS DALAM MENERIMA BERITA DAN ADAB DALAM BERKOMUNIKASI." Islamic Communication Journal 4, no. 2 (December 27, 2019): 146. http://dx.doi.org/10.21580/icj.2019.4.2.4014.

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<p><em>This paper seeks to parse the solution to the problem of hoax from the perspective of Quranic interpretation holistically and comprehensively. This study is a qualitative research by reading the relationship (munasabah) between verses about hoax in the Holy Quran that are represented by the terms ifk, fa&gt;siq, muna&gt;fiq, murjifu&gt;n, and tabayyun. After reading the verses related to the term, it was concluded that hoax news can be minimized by critical thinking, having emotional maturity, performing tabayyun, and broadening insight. In addition, the Holy Quran also teaches good communication ethics, namely qaulan sadi&gt;dan (correct speech), qaulan bali&gt;gan (good words that leave an imprint on the soul), qaulan maisu&gt;ran (proper speech), qaulan layyinan (soft words), qaulan kari&gt;man (noble words), and qaulan ma'ru&gt; fan (good words).</em></p><p> </p>
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Štulanović, Muharem. "POTVORA, OBJEDA ZA NEMORAL: BEZAZLENA BIZARNOST, TRIVIJALNOST ILI TEŠKI GRIJEH U ISLAMU." Zbornik radova Islamskog pedagoškog fakulteta u Bihaću 6, no. 6 (December 20, 2013): 73–99. http://dx.doi.org/10.52535/27441695.2013.6.73-99.

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Uzvišeni Allah, dž. š., šaljući Poslanike na zemlju, odgajao ih je, kao i njihove sljedbenike kroz upečatljive događaje i iskušenja iza kojih je davao odgojne mjere i koristi koje se nikada neće zaboraviti. Nije poslao ni jednog od poslanika, a da ga nisu optužili da je luđak, ludi pjesnik, čarobnjak, prorok i sl., pa su tako i nevjernici, politeisti, idolopoklonici Kurejša, na koncu svih poslaničkih misija, govorili za Muhammeda, a. s., čekajući priliku da mu na bilo koji način mogu naštetiti, napakostiti fizički ili moralno: njegovom ugledu i moralu ili njegovoj porodici. Samo jedan u nizu od tih napada jeste događaj ,,ifka-a“ (hadisetul-ifk) u kojem su htjeli da Allahovog Poslanika, a. s., degradiraju moralno i psihički sa potvorom i objedom na njegovu ženu, majku muslimana, Aišu, r. a., kćerku Ebu-Bekra es-Siddika Istinoljubivog. Nakon mjesec dana strahovitih muka i neprijatnosti, koje su se odrazile ne samo na Allahova Poslanika i Aišu, r. a., njenu porodicu, nego i na čitavo novoformirano muslimansko društvo i ashabe, Uzvišeni Allah će poslati Objavu kojom dokazuje nevinost Aiše, r. a., i kojom daje odgojne mjere i smjernice kojima će dalje kročiti muslimansko društvu nakon ovih strašnih događaja, ali će ukazati i na koristi svih ovih događanja kroz obznanjivanje i otkrivanje nečega što muslimani nisu znali, a to je da među njima ima prikrivenih licemjera koji su u njihovoj blizini i među njima. Dakle, ima onih koji nisu iskreni vjernici. Ovaj događaj će raslojiti muslimansko društvo na dvije kategorije: na iskrene vjernike koji su se držali istine i na one koji nisu, nego su se pretvarali da su vjernici i svoj prikriveni munafikluk i licemjerstvo koristili za napade na vjeru i vjernike.
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Nast, Irina, Andrea Mischker, Ute Repschläger, Michael Heine, Mandy Scheermesser, Markus Wirz, and Astrid Schämann. "Das Modellvorhaben Physiotherapie der BIG direkt gesund und des IFK e. V.: Welche Heilmittel wählen Physiotherapeuten bei Unabhängigkeit von der ärztlichen Verordnung?" physioscience 14, no. 02 (June 2018): 69–79. http://dx.doi.org/10.1055/a-0602-0947.

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Zusammenfassung Hintergrund In Ländern mit Direktzugang zur Physiotherapie wählen Physiotherapeuten autonom das bevorzugte Heilmittel zur Behandlung ihrer Patienten. Anders gestaltet sich die Situation in Deutschland: Hier verordnen die Ärzte das zu verwendende Heilmittel. Ziel Im Rahmen des Modellvorhabens Physiotherapie gemäß § 63 Abs. 3b SGB V wird (unter anderem) evaluiert, welche Heilmittel bei Behandlungsautonomie in welcher Frequenz und Dauer angewendet werden und welche Auswirkungen diese Wahl auf die Behandlungsergebnisse der Patienten hat. Methode Eine randomisierte kontrollierte Studie vergleicht die herkömmliche Behandlung nach ärztlicher Verordnung mit der Behandlung im neuen Versorgungsmodell hinsichtlich Wahl der Heilmittel, Behandlungsdauer und -frequenz sowie den Behandlungsergebnissen Patientenzufriedenheit (Fragebogen ZUF-8), Schmerz (visuelle Analogskala, VAS), gesundheitsbezogene Lebensqualität (Fragebogen EuroQol) und Funktion (Back Performance Scale [BPS], Roland-Morris Disability Questionnaire [RMDQ], Lower Extremity Functional Scale [LEFS]). Ergebnisse Am Modellvorhaben nahmen 630 Patienten teil, davon 296 in der Kontroll- (KG) und 334 in der Modellgruppe (MG). In der MG wendeten die Physiotherapeuten häufiger (in 33 % der Fälle) Allgemeine Krankengymnastik (AKG) und/oder Manuelle Therapie (MT) zusammen mit einem ergänzenden Heilmittel (z. B. Wärmetherapie-Fango) an (vs. 10 % in der KG; x2 = 51,525, p < 0,001) sowie häufiger eine Kombination aus AKG mit MT (in 32 % der Fälle vs. 3 % in der KG, x2 = 100,455, p < 0,001). Die Behandlungsdauer war in der MG mit 9,7 Wochen (Standardabweichung [SD] = 13,2) kürzer als in der KG mit 11,8 Wochen (SD = 5,4; T = 2,542, p < 0,05). Weitgehend unabhängig von ihrer Zugehörigkeit zur KG oder MG, berichteten die Patienten eine hohe Zufriedenheit und signifikante Verbesserungen hinsichtlich Schmerz, Lebensqualität und Funktion (Back Performance Scale [BPS], Roland-Morris Disability Questionnaire [RMDQ], Lower Extremity Functional Scale [LEFS]). Schlussfolgerung Bei Behandlungsfreiheit entschieden sich Physiotherapeuten vermehrt für eine Kombination von aktiven und passiven Behandlungstechniken, ohne die Behandlungsdauer auszudehnen. Dieses Vorgehen ist mit international anerkannten Behandlungsleitlinien konform.
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Day, J. Michael, and Gary R. Janssen. "Isolation and Characterization of Ribosomes and Translation Initiation Factors from the Gram-Positive Soil Bacterium Streptomyces lividans." Journal of Bacteriology 186, no. 20 (October 15, 2004): 6864–75. http://dx.doi.org/10.1128/jb.186.20.6864-6875.2004.

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ABSTRACT A primer extension inhibition (toeprint) assay was developed using ribosomes and ribosomal subunits from Streptomyces lividans. This assay allowed the study of ribosome binding to streptomycete leaderless and leadered mRNA. Purified 30S subunits were unable to form a ternary complex on aph leaderless mRNA, whereas 70S ribosomes could form ternary complexes on this mRNA. 30S subunits formed ternary complexes on leadered aph and malE mRNA. The translation initiation factors (IF1, IF2, and IF3) from S. lividans were isolated and included in toeprint and filter binding assays with leadered and leaderless mRNA. Generally, the IFs reduced the toeprint signal on leadered mRNA; however, incubation of IF1 and IF2 with 30S subunits that had been washed under high-salt conditions promoted the formation of a ternary complex on aph leaderless mRNA. Our data suggest that, as reported for Escherichia coli, initiation complexes with leaderless mRNAs might use a novel pathway involving 70S ribosomes or 30S subunits bound by IF1 and IF2 but not IF3. Some mRNA-ribosome-initiator tRNA reactions that yielded weak or no toeprint signals still formed complexes in filter binding assays, suggesting the occurrence of interactions that are not stable in the toeprint assay.
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Palubinskas, Edgaras, Narimantas Evaldas Samalavičius, and Lina Gudelytė. "Išangės fistulės kamščio metodo taikymas sudėtingai išangės fistulei gydyti." Lietuvos chirurgija 8, no. 4 (January 1, 2010): 0. http://dx.doi.org/10.15388/lietchirur.2010.4.2095.

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Edgaras Palubinskas1, Narimantas Evaldas Samalavičius2, Lina Gudelytė1 1 Vilniaus universiteto Medicinos fakultetas, M. K. Čiurlionio g. 21, LT-03101 Vilnius2 Vilniaus universiteto Onkologijos instituto Chirurgijos klinika ir Vilniaus universiteto Medicinos fakulteto Vidaus ligų, šeimos medicinos ir onkologijos klinika,Santariškių g. 1, LT-08406 VilniusEl. paštas: narimantas.samalavicius@vuoi.lt Tikslas: Tyrimo tikslas buvo įvertinti išangės fistulės kamščio (IFK) efektyvumą, gydant aukštas išangės fistules. Metodai: Į apžvalgą iš viso įtraukta 19 darbų iš 31, išspausdinto 2006–2010 m. Iš įtrauktųjų 8 yra retrospektyvinės studijos, 9 prospektyvinės, viena dvigubai akla randomizuota studija ir viena prospektyvinė nerandomizuota kontrolinė studija. Bendras į šias studijas įtrauktų ligonių, gydytų išangės fistulės kamščio metodu, skaičius yra 551. Rezultatai: Pooperacinio stebėjo laikas buvo nuo 3 iki 24 mėnesių. Gydymo išangės fistulės kamščiu sėkmingumas – nuo 15,6 % iki 88 %. Iš 551 IFK gydytų ligonių 300 (54,4 %) pasveiko. Kriptoglanduliarinės kilmės (K) fistulės buvo sėkmingai išgydytos 55,1 % atvejų, o įvairios kilmės (I) – 54,9 %. Neaptikome patikimo ryšio tarp sėkmingo gydymo rezultatų ir paciento lyties, amžiaus, fistulės ilgio ar kilmės. Išvados: Išangės fistulės kamščio metodas yra patikimas gydyti sudėtingas fistula-in-ano. Ateities tyrimai turėtų padėti aiškiau apibrėžti gydymo išangės fistulės kamščiu metodo vietą išangės fistulių chirurgijoje. Reikšminiai žodžiai: fistula-in-ano, išangės fistulės kamštis, ligos atkrytis, tiesiosios žarnos lopas. Anal fistula plug for the treatment of complex fistula-in-ano Edgaras Palubinskas1, Narimantas Evaldas Samalavičius2, Lina gudelytė1 1 Vilnius University Medical Faculty, M. K. Čiurlionio str. 21, LT-03101 Vilnius, Lithuania2 Vilnius University, Institute of Oncology, Clinic of Surgery,Santariškių str. 1, LT-08406 Vilnius, LithuaniaE-mail: narimantas.samalavicius@vuoi.lt Purpose: The aim of the study was to evaluate the efficacy of the anal fistula plug (AFP) for the treatment of fistula-in-ano. Methods: A total of 31 studies, published since 2006 to 2010 were extracted and 19 of them were finally included in this systematic review. 8 were retrospective case series, 9 prospective studies, 1 prospective non-randomized controlled trial and 1 randomized controlled trial. In these 19 studies, a total of 551 patients were included, who were treated with anal fistula plug. Results: The follow-up period ranged from 3–24 months. The AFP procedure had a success rate ranging from 15.6–88 %. From 551 patients treated with AFP, 300 (54.4 %) were cured. The success rate in patients with cryptoglandular origin (K) was 55.1 % and the success rate in patients with fistulas of other origin was 54.9 %. We did not notice difference in success rate between age, gender, fistula anatomy and etiology. Conclusion: The anal fistula plug method is a reliable method in treat of complex fistula-in-ano. Future studies should help to clarify the place of anal fistula plug in anal fistula surgery. Key words: Fistula-in-ano, anal plug, recurrence, advancement flap.
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Setiyanto, Danu Aris. "Hoax: Teks dan Konteks dalam Al-Quran." Indonesian Journal of Religion and Society 1, no. 1 (May 23, 2019): 1–11. http://dx.doi.org/10.36256/ijrs.v1i1.5.

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The development of technology has been shifted human’s way from the manual era to the digital era. Humans have been able to communicate without border and time. However, information in the modern era is not always true and many of them are false or hoaxes. Al Qur’an as a guide for humans has actually explained the hoax. Some words in the Al Qur'an illustrated the context of hoaxes such as ifk, kaẑaba, fitnah, khud'a, qaul al-zūr, buhtan, iftara, tahrif, and garur. In this paper, it will discuss the text of the hoax in the Al Qur’an in its text and textual verses when the verse is revealed. Furthermore, the context of the hoax in the Al Qur’an is explained in the context of the current issues with a semantic approach. This paper concludes that the meaning of the hoax in the Al Qur'an is in accordance with the recent context but only the media and problems are more complex. Furthermore, the Qur'an has provided solution to the issues of hoax such as checking the correctness of the data before sharing (Q. S Al-Hujurat: 6, Q. S Isra: 36), increasing the culture of literacy (Q. S Al-Qalam: 1 -2), awareness of prejudice (Q. S Al-Hujurat: 12), and so on.
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السندي, مسعود أحمد. "الفوائد والآثار الإيجابية لحادثة الإفك في ضوء السنة النبوية = Benefits and Positive Effects of the Incident of Ifk in the Light of Prophetic Sunnah." البصيرة 5, no. 2 (December 2016): 209–21. http://dx.doi.org/10.12816/0042409.

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Khan, Liakot A., Gholamali Jafari, Nan Zhang, Edward Membreno, Siyang Yan, Hongjie Zhang, and Verena Gobel. "A tensile trilayered cytoskeletal endotube drives capillary-like lumenogenesis." Journal of Cell Biology 218, no. 7 (June 25, 2019): 2403–24. http://dx.doi.org/10.1083/jcb.201811175.

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Unicellular tubes are components of internal organs and capillaries. It is unclear how they meet the architectural challenge to extend a centered intracellular lumen of uniform diameter. In an RNAi-based Caenorhabditis elegans screen, we identified three intermediate filaments (IFs)—IFA-4, IFB-1, and IFC-2—as interactors of the lumenal membrane-actin linker ERM-1 in excretory-canal tubulogenesis. We find that IFs, generally thought to affect morphogenesis indirectly by maintaining tissue integrity, directly promote lumenogenesis in this capillary-like single-cell tube. We show that ERM-1, ACT-5/actin, and TBB-2/tubulin recruit membrane-forming endosomal and flux-promoting canalicular vesicles to the lumen, whereas IFs, themselves recruited to the lumen by ERM-1 and TBB-2, restrain lateral vesicle access. IFs thereby prevent cystogenesis, equilibrate the lumen diameter, and promote lumen forward extension. Genetic and imaging analyses suggest that IFB-1/IFA-4 and IFB-1/IFC-2 polymers form a perilumenal triple IF lattice, sandwiched between actin and helical tubulin. Our findings characterize a novel mechanism of capillary-like lumenogenesis, where a tensile trilayered cytoskeletal endotube transforms concentric into directional growth.
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Amriarni, A., Budi Hendrarto, and Agus Hadiyarto. "BIOAKUMULASI LOGAM BERAT TIMBAL (Pb) DAN SENG (Zn) PADA KERANG DARAH (Anadara granosa L.) dan KERANG BAKAU (Polymesoda bengalensis L.) DI PERAIRAN TELUK KENDARI." Jurnal Ilmu Lingkungan 9, no. 2 (October 28, 2012): 45. http://dx.doi.org/10.14710/jil.9.2.45-50.

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Perkembangan wilayah pesisir Teluk Kendari cukup pesat dengan berbagai macam aktivitas baik berupa jasa kelautan seperti pelabuhan untuk pelayaran dan perikanan maupun kegiatan-kegiatan di sekitar pantai seperti pemukiman, industri, usaha dan pertambakan. Adanya logam berat di perairan, berbahaya baik secara langsung terhadap kehidupan kerang darah (Anadara. granosa) dan kerang bakau (Polymesoda bengalensis), maupun efeknya secara tidak langsung terhadap kesehatan manusia. Penelitian ini bertujuan untuk menganalisis kandungan logam berat Pb dan Zn pada air, sedimen, dan jaringan kerang dan mengkaji faktor bioakumulasi logam berat Pb dan Zn pada dua jenis kerang. Sampel air, sedimen dan kerang diambil pada kedua lokasi pengambilan kerang, tiap lokasi 3 titik pengambilan dengan 3 kali ulangan analisis. Hasil Penelitian menunjukkan bahwa logam Pb dan Zn di air pada tiap lokasi telah melampau baku mutu, kadar tertinggi masing-masing 0,018 mg/L dan 0,793 mg/L, sedangkan pada sedimen tertinggi masing-masing 0,823 mg/Kg dan 6,919 mg/Kg, dan pada jaringan kerang menunjukan hasil bahwa kerang ukuran besar mengandung logam Pb dan Zn lebih tinggi, masing-masing 1,750 dan 9,863 mg/Kg. (sedimen dan kerang belum melampau baku mutu). Nilai BCFo-w logam Pb tertinggi 119,20 pada kerang bakau dan Zn tertinggi 35,99 pada kerang darah. Berdasarkan kategori nilai IFK (BCF) untuk logam Pb dan Zn termasuk dalam kategori rendah hingga sedang.
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Syakur, Abdul, Christyana Sandra, and Candra Bumi. "Evaluasi Cold Chain Management Vaksin di Puskesmas Kabupaten Jember." Jurnal Manajemen Kesehatan Indonesia 9, no. 1 (April 28, 2021): 21–27. http://dx.doi.org/10.14710/jmki.9.1.2021.21-27.

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Immunization is the most cost-effective health prevention method to suppress the incidence of vaccine-preventable disease. Immunization Program in Jember district is still not optimal with many vaccine-preventable disease cases found. Another problem found in Jember is the management of logistics vaccine that is still not optimal. Based on the activity plan report of ORI Difteri 2018, it is known that the logistics needs of some vaccines do not comply with the allocation received by Jember regency of the province. This condition This was a descriptive study using questionaire and observations data as well as the documentation study of the annual Report of Health Pharmacy Installation (IFK) year 2019. Respondent to this study were immunization officers at primary health care of Jember District. The result of cold chain management evaluation is known that the most are good enaugh. In some primary health care are still hampered insufficient means so that the maintenance of vaccine is still not optimalBased on the result that cold chain management evaluation, the knowledge officer on cold chain management is still lacking good. In the some primary health care, it is known that the equipment canstraints are unavailable. While in the conformity of temperature only one primary helath care is not recommended. And stirage activities are mostly in accordance with SOP.
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Muhammad Yusram and Azwar Iskandar. "Cadar dan Hukumnya: Bantahan Terhadap Penolakan Pensyariatannya." NUKHBATUL 'ULUM: Jurnal Bidang Kajian Islam 6, no. 1 (June 12, 2020): 1–21. http://dx.doi.org/10.36701/nukhbah.v6i1.92.

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This study aimed to examine and explain the passages or propositions for the inquiry of veil use, some opinions of leading scholars, and to correct or refute some weak and controversial statements and interpretations related to veil and its law. This research employed qualitative-descriptive approach with content analysis technique and library research. The result shows that the veil is prescribed in Islam. This is based on the word of Allah in the Quran surah Al-Ahzab verse 59 which is interpreted by commentators among the companions and tabi'in as a command to cover the face. In the long story of ‘ifk, it is also mentioned that Aisyah covered her face. The scholars of schools (Hanafiyyah, Malikiyyah, Syafiiyyah, and Hanabilah), even though they disagree whether covering the face is obligatory or sunnah, they agree that veil is something recommended, specifically at the time when it is feared of triggering tribulation in society due to showing off the faces of women. Some commentators also hold that they must cover their faces as they emphasize in their commentaries. Some interpretations or statements related to veil as well as its law are weak. For example, the interpretation that the use of veil that prevailed in Arab societies was a tradition for certain societies is such a fallacious statement. Considering the existing history, the previous Arab communities which were commonly called the jahiliyyah community were ignorant about covering, let alone the veil.
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Franceschi, Piero, Massimo Malacarne, Paolo Formaggioni, Michele Faccia, and Andrea Summer. "Quantification of the Effect of the Cattle Breed on Milk Cheese Yield: Comparison between Italian Brown Swiss and Italian Friesian." Animals 10, no. 8 (August 1, 2020): 1331. http://dx.doi.org/10.3390/ani10081331.

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Milk from different cattle breeds can present different casein and fat contents, which are reflected in different cheese yields (CY). However, CY is also related to some breed-related molecular characteristics. The aim of the present work was to quantify the effect of these characteristics by comparing a series of Parmigiano Reggiano (PR) cheese-making trials made with milks from Italian Brown (IB) and Italian Friesian (IF) cattle herds. Twelve trials were carried out in a cheese factory in one year (one trial per month), each one consisting of four vats processed in parallel: three vats contained milk from three different IF cattle herds (IF1, IF2 and IF3) and one contained milk from a single IB cattle herd. A 24-h CY prediction formula was developed with data from IF1, IF2 and IF3 trials (calibration) and successively validated by applying it to 12 PR trials made with IF milk in six different cheese factories (external validation). The predicted values of 24-h CY were no different to the actual ones in both calibration and external validation. Finally, the formula was tested on trials made with IB milk. In this case, the predicted values were lower than the actual ones. The quantity of IF milk casein necessary to give the same CY of IB milk was 0.20 g/100 g.
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Liu, Qi, and Kurt Fredrick. "Roles of helix H69 of 23S rRNA in translation initiation." Proceedings of the National Academy of Sciences 112, no. 37 (August 31, 2015): 11559–64. http://dx.doi.org/10.1073/pnas.1507703112.

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Initiation of translation involves the assembly of a ribosome complex with initiator tRNA bound to the peptidyl site and paired to the start codon of the mRNA. In bacteria, this process is kinetically controlled by three initiation factors—IF1, IF2, and IF3. Here, we show that deletion of helix H69 (∆H69) of 23S rRNA allows rapid 50S docking without concomitant IF3 release and virtually eliminates the dependence of subunit joining on start codon identity. Despite this, overall accuracy of start codon selection, based on rates of formation of elongation-competent 70S ribosomes, is largely uncompromised in the absence of H69. Thus, the fidelity function of IF3 stems primarily from its interplay with initiator tRNA rather than its anti-subunit association activity. While retaining fidelity, ∆H69 ribosomes exhibit much slower rates of overall initiation, due to the delay in IF3 release and impedance of an IF3-independent step, presumably initiator tRNA positioning. These findings clarify the roles of H69 and IF3 in the mechanism of translation initiation and explain the dominant lethal phenotype of the ∆H69 mutation.
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Laursen, Brian Søgaard, Hans Peter Sørensen, Kim Kusk Mortensen, and Hans Uffe Sperling-Petersen. "Initiation of Protein Synthesis in Bacteria." Microbiology and Molecular Biology Reviews 69, no. 1 (March 2005): 101–23. http://dx.doi.org/10.1128/mmbr.69.1.101-123.2005.

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SUMMARY Valuable information on translation initiation is available from biochemical data and recently solved structures. We present a detailed description of current knowledge about the structure, function, and interactions of the individual components involved in bacterial translation initiation. The first section describes the ribosomal features relevant to the initiation process. Subsequent sections describe the structure, function, and interactions of the mRNA, the initiator tRNA, and the initiation factors IF1, IF2, and IF3. Finally, we provide an overview of mechanisms of regulation of the translation initiation event. Translation occurs on ribonucleoprotein complexes called ribosomes. The ribosome is composed of a large subunit and a small subunit that hold the activities of peptidyltransfer and decode the triplet code of the mRNA, respectively. Translation initiation is promoted by IF1, IF2, and IF3, which mediate base pairing of the initiator tRNA anticodon to the mRNA initiation codon located in the ribosomal P-site. The mechanism of translation initiation differs for canonical and leaderless mRNAs, since the latter is dependent on the relative level of the initiation factors. Regulation of translation occurs primarily in the initiation phase. Secondary structures at the mRNA ribosomal binding site (RBS) inhibit translation initiation. The accessibility of the RBS is regulated by temperature and binding of small metabolites, proteins, or antisense RNAs. The future challenge is to obtain atomic-resolution structures of complete initiation complexes in order to understand the mechanism of translation initiation in molecular detail.
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Nakamoto, Jose A., Wilfredo Evangelista, Daria S. Vinogradova, Andrey L. Konevega, Roberto Spurio, Attilio Fabbretti, and Pohl Milón. "The dynamic cycle of bacterial translation initiation factor IF3." Nucleic Acids Research 49, no. 12 (June 23, 2021): 6958–70. http://dx.doi.org/10.1093/nar/gkab522.

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Abstract Initiation factor IF3 is an essential protein that enhances the fidelity and speed of bacterial mRNA translation initiation. Here, we describe the dynamic interplay between IF3 domains and their alternative binding sites using pre-steady state kinetics combined with molecular modelling of available structures of initiation complexes. Our results show that IF3 accommodates its domains at velocities ranging over two orders of magnitude, responding to the binding of each 30S ligand. IF1 and IF2 promote IF3 compaction and the movement of the C-terminal domain (IF3C) towards the P site. Concomitantly, the N-terminal domain (IF3N) creates a pocket ready to accept the initiator tRNA. Selection of the initiator tRNA is accompanied by a transient accommodation of IF3N towards the 30S platform. Decoding of the mRNA start codon displaces IF3C away from the P site and rate limits translation initiation. 70S initiation complex formation brings IF3 domains in close proximity to each other prior to dissociation and recycling of the factor for a new round of translation initiation. Altogether, our results describe the kinetic spectrum of IF3 movements and highlight functional transitions of the factor that ensure accurate mRNA translation initiation.
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Riis, Søren. "Count(ifq) does not imply Count(ifp)." Annals of Pure and Applied Logic 90, no. 1-3 (December 1997): 1–56. http://dx.doi.org/10.1016/s0168-0072(97)00029-8.

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43

Schuster, Gunnar, and Heinrich Nemeczek. "IFR, IFD und WpIG – Neuer Rechtsrahmen für Wertpapierfirmen." Zeitschrift für Bankrecht und Bankwirtschaft 33, no. 2 (April 14, 2021): 121–31. http://dx.doi.org/10.15375/zbb-2021-0207.

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Zusammenfassung Der folgende Beitrag setzt den ersten Teil, der in ZBB 2021, 35 erschienen ist, fort und behandelt die neuen Kapital- und Liquiditätsanforderungen an Wertpapierfirmen, die Aufsichtsanforderungen an Konzentrationsrisiken, die Änderungen bei der aufsichtlichen Konsolidierung sowie die Vorgaben zur internen Unternehmensführung und zur Vergütung.
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Cruz, Gustavo Henrique Miguel da, Fernando França da Cunha, Epitácio José de Souza, Andrisley Joaquim da Silva, and Roberto Filgueiras. "IRRIGATION FREQUENCIES FOR Eucalyptus grandis SEEDLINGS." REVISTA ENGENHARIA NA AGRICULTURA - REVENG 28 (November 26, 2020): 364–74. http://dx.doi.org/10.13083/reveng.v29i1.9669.

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One of the bottlenecks in relation to the production of forest seedlings is irrigation, especially in less-tech nurseries. The small volumes of substrate, where the seedlings develop, lead to low water storage. This fact can lead to water deficit and significant losses in the production of seedlings, generating even mortality. The objective of this study was to determine the best irrigation frequencies for Eucalyptus grandis seedling production in less-tech nurseries. The experiment was conducted between 2013/08/04 and 2013/23/07 (106 days) and conducted in Chapadão do Sul county, Brazil. The experiment was set up in a randomized complete block design, with five replications. Four irrigation frequencies were tested: IF1 (one daily irrigation - 11:00 a.m.), IF2 (two daily irrigations - 11:00 a.m. and 7:00 p.m.), IF3 (three daily irrigations - 07:00 a.m., 11:00 a.m. and 7:00 p.m.) and IF4 (four daily irrigations - 07:00 a.m., 11:00 a.m., 3:00 p.m. and 7:00 p.m.). The sample units were composed of eight seedlings in 50 cm3 conical tubes filled with soil and vermiculite in a volume ratio of 1:1. The irrigation depth was estimated by reference evapotranspiration (Penman-Monteith) multiplied by a crop coefficient equal to two. Plant height, number of definitive leaves, shoot dry mass (root and total), seed quality index, survival and efficiency of water use by eucalyptus seedlings were evaluated. The average daily irrigation depth in the experimental period was 5.2 mm. Based on the results, it is recommended for eucalyptus seedling producers, in less-tech nursery, irrigation management twice per days. (11:00 a.m. and 7:00 p.m.).
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Chu, Rose S., Oleg S. Targoni, Arthur M. Krieg, Paul V. Lehmann, and Clifford V. Harding. "CpG Oligodeoxynucleotides Act as Adjuvants that Switch on T Helper 1 (Th1) Immunity." Journal of Experimental Medicine 186, no. 10 (November 17, 1997): 1623–31. http://dx.doi.org/10.1084/jem.186.10.1623.

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Synthetic oligodeoxynucleotides (ODN) that contain unmethylated CpG motifs (CpG ODN) induce macrophages to secrete IL-12, which induces interferon (IFN)-γ secretion by natural killer (NK) cells. Since these cytokines can induce T helper 1 (Th1) differentiation, we examined the effects of coadministered CpG ODN on the differentiation of Th responses to hen egg lysozyme (HEL). In both BALB/c (Th2-biased) and B10.D2 (Th1-biased) mice, immunization with HEL in incomplete Freund's adjuvant (IFA) resulted in Th2-dominated immune responses characterized by HEL-specific secretion of IL-5 but not IFN-γ. In contrast, immunization with IFA-HEL plus CpG ODN switched the immune response to a Th1-dominated cytokine pattern, with high levels of HEL-specific IFN-γ secretion and decreased HEL-specific IL-5 production. IFA-HEL plus CpG ODN also induced anti-HEL IgG2a (a Th1-associated isotype), which was not induced by IFA-HEL alone. Control non–CpG ODN did not induce IFN-γ or IgG2a, excepting lesser increases in B10.D2 (Th1-biased) mice. Thus, CpG ODN provide a signal to switch on Th1-dominated responses to coadministered antigen and are potential adjuvants for human vaccines to elicit protective Th1 immunity.
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Rolain, J. M., F. Gouriet, M. Enea, M. Aboud, and D. Raoult. "Detection by Immunofluorescence Assay of Bartonella henselae in Lymph Nodes from Patients with Cat Scratch Disease." Clinical Diagnostic Laboratory Immunology 10, no. 4 (July 2003): 686–91. http://dx.doi.org/10.1128/cdli.10.4.686-691.2003.

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ABSTRACT Laboratory diagnosis of Bartonella henselae infections can be accomplished by serology or PCR assay on biopsy samples. The purpose of our work was to assess immunofluorescence detection (IFD) in lymph node smears using a specific monoclonal antibody directed against B. henselae and a commercial serology assay (IFA) compared with PCR detection. Among 200 lymph nodes examined from immunocompetent patients, 54 were positive for B. henselae by PCR, of which 43 were also positive by IFD. Among the 146 PCR-negative lymph nodes, 11 were positive by IFD. Based on PCR results, the specificity of this new technique was 92.5%, the sensitivity was 79.6%, and the positive predictive value was 79.6%. At a cutoff titer of 64, the sensitivity of the IFA was 86.8% and the specificity was 74.1%. Diagnosis of cat scratch disease (CSD) may be improved, with a specificity of 100%, when the two tests (IFD and IFA) were negative; the sensitivity was 97.4% if one of the two tests was positive. Since PCR-based detection with biopsy samples is available only in reference laboratories, we suggest using IFD coupled with the commercial serology test for the diagnosis of CSD.
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47

Karabinos, Anton. "Intermediate filament (IF) proteins IFA-1 and IFB-1 represent a basic heteropolymeric IF cytoskeleton of nematodes: A molecular phylogeny of nematode IFs." Gene 692 (April 2019): 44–53. http://dx.doi.org/10.1016/j.gene.2018.12.069.

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48

Pediconi, Dario, Roberto Spurio, Anna La Teana, David Jemiolo, Claudio O. Gualerzi, and Cynthia L. Pon. "Translational regulation of infC operon in Bacillus stearothermophilus." Biochemistry and Cell Biology 73, no. 11-12 (December 1, 1995): 1071–78. http://dx.doi.org/10.1139/o95-115.

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A Bacillus stearothermophilus in vitro translational system has been developed to study the expression of the three cistrons (infC, rpmI, and rplT) constituting the infC operon of this bacterium. When directed by homologous in vitro transcribed infC tricistronic mRNA, this system, which consists of partially purified and purified components of the B. stearothermophilus translational apparatus, synthesizes with high efficiency and specificity the three gene products (IF3, L35, and L20) in a ratio similar to that found in vivo (i.e., about 1:6:6). The three cistrons are translationally coupled and expressed in a specific temporal order: a low level of IF3 synthesis stimulates the expression of L35 which, in turn, greatly stimulates the synthesis of L20 and IF3. Protein L20 and an excess of IF3 were found to act as translational feedback inhibitors of the entire operon. The synthesis of IF3 displayed a strong dependence on IF2. This dependence as well as the repressibility by excess IF3 were found to be due to the presence of the rare AUU initiation triplet at the beginning of infC.Key words: translational coupling, IF3, IF2, L35, L20.
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Soffientini, A., R. Lorenzetti, L. Gastaldo, J. H. Parlett, R. Spurio, A. Lateana, and K. Islam. "Purification Procedure for Bacterial Translational Initiation Factors IF2 and IF3." Protein Expression and Purification 5, no. 2 (April 1994): 118–24. http://dx.doi.org/10.1006/prep.1994.1018.

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50

Schuster, Gunnar, and Heinrich Nemeczek. "IFR, IFD und WpIG – Neuer Rechtsrahmen für Wertpapierfirmen (Teil 1)." Zeitschrift für Bankrecht und Bankwirtschaft 33, no. 1 (February 15, 2021): 35–47. http://dx.doi.org/10.15375/zbb-2021-0105.

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Zusammenfassung Wertpapierfirmen müssen sich auf ein neues, komplexes Aufsichtsregime einrichten, das am 26. 6. 2021 in Kraft tritt. Es soll den besonderen Risiken, die von Wertpapierfirmen für die Finanzstabilität ausgehen, besser Rechnung tragen als das bisher für sie maßgebliche Aufsichtsregime für Kreditinstitute. Lediglich die größten Wertpapierfirmen sollen weiterhin als CRR-Kreditinstitute beaufsichtigt werden. Der Beitrag behandelt in vorliegendem ersten Teil die ausdifferenzierte Kategorisierung der Wertpapierfirmen. In einem zweiten Teil des Beitrags, der in der kommenden Ausgabe der ZBB erscheint, werden die Kapital- und Liquiditätsanforderungen, die Aufsichtsanforderungen an Konzentrationsrisiken, die Änderungen zur aufsichtlichen Konsolidierung sowie die Vorgaben zur internen Unternehmensführung und zur Vergütung behandelt.
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