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1

Li, Rui, and Zhi Peng Ge. "Intersection Safety Evaluation Model Based on Traffic Conflict and Accident Data." Advanced Materials Research 1065-1069 (December 2014): 3320–24. http://dx.doi.org/10.4028/www.scientific.net/amr.1065-1069.3320.

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The severity of accidents can show the dangerous of intersections directly, however, the safety of intersections which have not accident data could not be evaluated easily. This paper introduced “Intersection Dangerous Parameter (IDP)” model to quantify intersections’ safety. Because IDP is calculated based on Intersection Conflict Dangerous Parameter (ICDP) and Intersection Accident Dangerous Parameter (IADP), IDP model can help to evaluate the safety of intersections which have not accident data. Rely on Chinese and American data, IDP model is calibrated and the safeties of three type intersections are evaluated using this method.
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Gogoi, Rakhi Moni. "Contextualizing IDP." Asian Journal of Research in Social Sciences and Humanities 11, no. 2 (2021): 1–4. http://dx.doi.org/10.5958/2249-7315.2021.00003.4.

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3

Baum, Jean. "Modulating Alpha-Synuclein Aggregation through IDP-IDP Interactions." Biophysical Journal 116, no. 3 (February 2019): 4a. http://dx.doi.org/10.1016/j.bpj.2018.11.049.

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4

Goswami, U. "IDP LIVELIHOODS: Enabling Idp Livelihoods in Western Assam: Nobody's Responsibility." Refugee Survey Quarterly 25, no. 2 (January 1, 2006): 60–68. http://dx.doi.org/10.1093/rsq/hdi0125.

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Bibang Bi Obam Assoumou, Stahel Serano, Li Zhu, and Christopher Khayeka-Wandabwa. "Invigorating Health Strategy in an Integrated Design Process." Smart Cities 5, no. 3 (July 27, 2022): 819–31. http://dx.doi.org/10.3390/smartcities5030042.

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Healthy buildings are gaining crucial significance in construction and one health setting for promoting occupants’ health. However, the traditional design process for healthy buildings presents limitations with no specific guidelines. In contrast, the integrated design process (IDP) has proven to be effective in realizing high-performance buildings. However, the IDP shortfall of not having robust health strategy (HS) capability is a concern of interest. Thus, we posit further advancement of IDP in the context of incorporating HS in the prevailing IDP guidelines with a sequential iterative procedure. Moreover, a conceptual framework aimed at invigorating the implementation of HS in all IDP stages is proposed. The strategies within IDP that would reinforce achieving healthy building by addressing building process implementation are highlighted. The (IDP + HS) iterative framework herein advanced is intended to aid neophyte and experienced building professionals to reflect about the process of achieving healthy building while optimizing IDP for one’s health invigoration in construction industry.
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B, Vignesh, and Dr J. Krithika. "An Overview on IDP and Its Significance in Business." International Journal for Research in Applied Science and Engineering Technology 10, no. 10 (October 31, 2022): 381–86. http://dx.doi.org/10.22214/ijraset.2022.47001.

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Abstract: The practice of intelligently acquiring specific information and expediting document processing processes is known as intelligent data processing. The surge of SaaS industry has led to a great demand for automation especially for Intelligent Document processing (IDP) solution, IDP industry is expected to raise to a greater extent amid increased use of AI and OCR technologies and software. This article discusses about Global Automation Industrial Market with a special focus on IDP, the further chapters of the papers focus on IDP solutions and the significance of IDP. The middle part of the article discusses the global market of the IDP and its future scope in India. The author could able to find some relevant findings and recommended some plan of actions. The complete report provides a detailed overview of the SaaS – IDP industry and also about integration in India business.
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Bradley, Miriam. "Unintended Consequences of Adjacency Claims." Global Governance: A Review of Multilateralism and International Organizations 25, no. 4 (December 10, 2019): 620–44. http://dx.doi.org/10.1163/19426720-02504002.

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Abstract This article examines the role of adjacency claims in the development of a norm for the international protection of internally displaced persons (IDP s). Consistent with existing scholarship on adjacency claims, the construction of analogies between refugee protection and IDP protection was instrumental in garnering broad international acceptance of the IDP protection norm. However, these same analogies had an impact beyond the abstract acceptance of the norm. They were used to justify the expansion of the mandate of the UN Refugee Agency (UNHCR) to encompass IDP s, and they shaped the way UNHCR understands and implements IDP protection. UNHCR replicated its policy approach from refugees to IDP s, generating a dysfunctional approach to IDP protection. Therefore, adjacency claims can have an effect beyond garnering support for new norms, and may result in suboptimal governance arrangements for implementing those norms.
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Lee, Myongjae, Yoo-Seong Jeong, Min-Soo Kim, Kyung-Mi An, and Suk-Jae Chung. "Prediction of Pharmacokinetics of IDP-73152 in Humans Using Physiologically-Based Pharmacokinetics." Pharmaceutics 14, no. 6 (May 28, 2022): 1157. http://dx.doi.org/10.3390/pharmaceutics14061157.

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IDP-73152, a novel peptide deformylase inhibitor with an antibacterial effect against Gram-positive bacteria, is in phase I development. The objective of this study was to develop a physiologically-based pharmacokinetic model (PBPK) for IDP-73152 in animals, and to extend the model to humans. Biopharmaceutical properties of IDP-73152 are determined using in vitro/in vivo experimentations for the PBPK model. A transit model consisting of gastrointestinal segments is applied for an estimation of the intestinal absorption kinetics. The PBPK model of IDP-73152 in rats is able to appropriately predict the plasma concentration–time profiles after the administration of IDP-73152 at different doses and by different routes (combined absolute average fold error (cAAFE), 1.77). The model is also found to be adequate in predicting the plasma concentration–time profiles of IDP-73152 in mice (cAAFE 1.59) and dogs (cAAFE 1.42). Assuming the oral administration of IDP-73152 to humans at doses of 640 and 1280 mg, the model is able to reproduce the concentration–time profiles obtained in humans (cAAFE 1.38); therefore, these observations indicate that the PBPK model used for IDP-73152 is applicable to animal species and humans. This model may be useful in predicting efficacious doses of IDP-73152 for the management of infectious disease in humans.
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Rosborough, Stephanie. "Tent Community in Kashmir, 2005: To IDP or Not to IDP?" Disaster Medicine and Public Health Preparedness 3, no. 2 (June 2009): 63. http://dx.doi.org/10.1097/dmp.0b013e3181a846c7.

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Clark, Sarah A., Nathan Jespersen, Clare Woodward, and Elisar Barbar. "Multivalent IDP assemblies: Unique properties of LC8-associated, IDP duplex scaffolds." FEBS Letters 589, no. 19PartA (July 29, 2015): 2543–51. http://dx.doi.org/10.1016/j.febslet.2015.07.032.

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Facó, Olivardo, Raimundo Nonato Braga Lôbo, Raimundo Martins Filho, Gabrimar Araújo Martins, Sônia Maria Pinheiro de Oliveira, and Danielle Maria Machado Ribeiro Azevêdo. "Efeitos genéticos aditivos e não-aditivos para características produtivas e reprodutivas em vacas mestiças Holandês × Gir." Revista Brasileira de Zootecnia 37, no. 1 (January 2008): 48–53. http://dx.doi.org/10.1590/s1516-35982008000100006.

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A partir de registros de genealogia e controle leiteiro e reprodutivo fornecidos pela Associação Brasileira dos Criadores de Girolando, foram estimados os efeitos de diferença genética aditiva entres as raças Holandesa e Gir, de dominância e de recombinação, além das herdabilidades e repetibilidades, para as características produção de leite por lactação (PL), produção de leite até os 305 dias de lactação (PL305), duração da lactação (DL), intervalo de partos (IDP), idade ao primeiro parto (IPP) e produção de leite por dia de intervalo de partos (PL/IDP). Foram utilizados 4.805 registros de PL, PL305 e DL e 2.222, 1.408 e 2.363 registros de IDP, IPP e PL/IDP, respectivamente. Análises unicaracterísticas foram realizadas considerando os efeitos de diferença genética aditiva entre as raças, de dominância e de recombinação como covariáveis. As estimativas para a diferença genética aditiva entre as duas raças foram significativas para todas as características, exceto para o IDP, e foram estimadas em 3.115 ± 273 kg, 2.574 ± 226 kg, 98 ± 13 dias, -236 ± 67 dias e 7,5 ± 0,9 kg/dia para PL, PL305, DL, IPP e PL/IDP, respectivamente. Os efeitos de dominância (heterose) também foram significativos para todas as características, exceto para a DL. Foi verificada significativa perda por recombinação para PL e PL305. As estimativas de herdabilidade foram de 0,25 ± 0,05, 0,21 ± 0,04, 0,12 ± 0,04, 0,05 ± 0,05, 0,33 ± 0,09 e 0,21 ± 0,07 para PL, PL305, DL, IDP, IPP e PL/IDP, respectivamente, enquanto as estimativas de repetibilidade foram de 0,49 ± 0,05; 0,47 ± 0,04; 0,18 ± 0,04; 0,09 ± 0,06; e 0,37 ± 0,07 para PL, PL305, DL, IDP e PL/IDP, respectivamente.
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Kaaba, Imran, Fadly Achmad, and Frice L. Desei. "UJI DURABILITAS DAN PENUAAN CAMPURAN BERASPAL LAPIS AUS (AC-WC) DENGAN BAHAN TAMBAH LIMBAH BOTOL PLASTIK TERHADAP VARIASI LAMA RENDAMAN." FROPIL (Forum Profesional Teknik Sipil) 10, no. 1 (August 28, 2022): 32–39. http://dx.doi.org/10.33019/fropil.v10i1.2852.

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Penambahan plastik polimer ke dalam aspal dapat dilakukan dengan cara basah atau cara kering, stabilitas campuran aspal beton yang dicampur plastik PET terbukti dapat meningkatkan nilai stabilitas. Pengujian durabilitas dan penuaan digunakan untuk mengetahui nilai Indeks Kekuatan Sisa (IKS), Indeks Durabilitas Pertama (IDP), dan Indeks Durabilitas Kedua (IDK). Pembuatan benda uji STOA dilakukan dengan cara memasukkan benda uji dalam keadaan curah ke dalam oven selama 4 jam dengan suhu 135°C, sedangkan untuk LTOA benda uji di oven dalam keadaan padat selama 2 hari dengan suhu 85°C, kemudian direndam pada waterbatch dengan suhu 60°C dengan variasi lama rendaman 0,5 jam, 24 jam, 48 jam, 72 jam, 96 jam. Parameter keawetan campuran dilihat dari IKS, IDP, dan IDK. Berdasarkan hasil penelitian nilai kadar aspal yang diperoleh melalui hasil penelitian sebelumnya sebesar 6,75%. Nilai stabilitas untuk benda uji normal, STOA, dan LTOA secara berturut-turut sebesar 1.178,97 kg, 1.057,68 kg, dan 955,79 kg. Nilai IKS pada benda uji normal, STOA, dan LTOA secara berturut-turut sebesar 95,88%, 93,58%, 91,88%. IDP dengan nilai kelandaian (r) untuk benda uji normal, STOA dan LTOA secara berturut-turut sebesar 0,64%, 0,88%, dan 0,98%. IDK benda uji normal, STOA, dan LTOA untuk nilai (a) secara berturut-turut sebesar 7,35%, 10,76%, dan 12,29%. KAO pada pemeriksaan Marshall Test kali ini merupakan campuran aspal dengan plastik sebanyak 1,2% campuran wet process memiliki nilai durabilitas tertinggi yaitu 95,88 %. Semakin lama rendaman maka semakin rendah nilai stabilitas yang didapatkan.
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13

Rahwan, Talal, Tomasz Michalak, and Nicholas Jennings. "A Hybrid Algorithm for Coalition Structure Generation." Proceedings of the AAAI Conference on Artificial Intelligence 26, no. 1 (September 20, 2021): 1443–49. http://dx.doi.org/10.1609/aaai.v26i1.8265.

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The current state-of-the-art algorithm for optimal coalition structure generation is IDP-IP — an algorithm that combines IDP (a dynamic programming algorithm due to Rahwan and Jennings, AAAI'08) with IP (a tree-search algorithm due to Rahwan et al., JAIR'09). In this paper we analyse IDP-IP, highlight its limitations, and then develop a new approach for combining IDP with IP that overcomes these limitations.
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Hadži, San, Remy Loris, and Jurij Lah. "The sequence–ensemble relationship in fuzzy protein complexes." Proceedings of the National Academy of Sciences 118, no. 37 (September 9, 2021): e2020562118. http://dx.doi.org/10.1073/pnas.2020562118.

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Intrinsically disordered proteins (IDPs) interact with globular proteins through a variety of mechanisms, resulting in the structurally heterogeneous ensembles known as fuzzy complexes. While there exists a reasonable comprehension on how IDP sequence determines the unbound IDP ensemble, little is known about what shapes the structural characteristics of IDPs bound to their targets. Using a statistical thermodynamic model, we show that the target-bound ensembles are determined by a simple code that combines the IDP sequence and the distribution of IDP–target interaction hotspots. These two parameters define the conformational space of target-bound IDPs and rationalize the observed structural heterogeneity of fuzzy complexes. The presented model successfully reproduces the dynamical signatures of target-bound IDPs from the NMR relaxation experiments as well as the changes of interaction affinity and the IDP helicity induced by mutations. The model explains how the target-bound IDP ensemble adapts to mutations in order to achieve an optimal balance between conformational freedom and interaction energy. Taken together, the presented sequence–ensemble relationship of fuzzy complexes explains the different manifestations of IDP disorder in folding-upon-binding processes.
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Adeeva, Tatiana, Inna Tikhonova, Svetlana Khazova, Ulyana Sevastyanova, and Natalia Shipova. "Variants of inward disorder pattern among adolescents with different dysontogenesis." SPECIALUSIS UGDYMAS / SPECIAL EDUCATION 1, no. 42 (December 30, 2021): 61–97. http://dx.doi.org/10.15388/se.v1i42.558.

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Adolescence is one of the key stages of personality development. That of adolescents with disabilities follows a non-disabled pattern. However, the process is affected by dysontogenesis, which is considered a factor that significantly affects personality development. Inward disorder pattern (IDP) is considered a complex integrative construct; a system of one’s sensations, knowledge, emotional experiences, motivation shifts caused by a disorder. IDP is considered a component of I-concept, a factor affecting its development and crucial for an individual’s functioning. Aim of the research: to identify the IDP variants of adolescents with disabilities. The sample consisted of 109 adolescents with disabilities. Their average age is 14. High indices on one or several IDP components serve to distinguish the IDP variants among adolescents. Each IDP variant is marked by respondents’ specific personal traits and I-concept features. The analysis of the ratio reveals an individual’s general behavioral pattern and attitude to their disorder. We introduce four IDP variants in the adolescent group for the moment: cognitive-emotional (tense), sensitive-cognitive (sensitive-autistic), sensitive-emotional (anxious-hypochondriac), and balanced.
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Borowicz, Aleksandra. "Evaluation of the Investment Development Path concept in selected Baltic Sea Region states: Where are we?" Rocznik Instytutu Europy Środkowo-Wschodniej 19, no. 3 (December 2021): 77–100. http://dx.doi.org/10.36874/riesw.2021.3.4.

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In the European Union (EU), there are four Baltic Sea Region (BSR) states – Estonia, Latvia, Lithuania, and Poland – which are interlinked by the following facts: the common moment of obtaining EU membership, a common historical path from communism to democracy, and being part of the BSR. Although the selected countries share common roots, it seems that, in terms of the economic development, they may follow a different path. Investment development path (IDP), a concept developed by J.H. Dunning, stresses that the development of a country is a result of being an active exporter of capital. This paper aims to evaluate the progress of the four selected economies in terms of their IDP. The analysis takes into consideration their peculiar economic determinants. The methods used include quantitative and qualitative methods. Among the qualitative methods, a literature review briefly presents Dunning’s IDP paradigm. The review of existing empirical research highlights the contributions of the paper. The quantitative methods cover the statistical data illustrating the progress of the selected countries in terms of the IDP. The data were obtained from United Nations Conference on Trade and Development (UNCTADStat) and Eurostat. The BSR states under investigation differ in terms of their economic growth. However, they share a common denominator of maintaining the role of importer of capital. The highest dynamics of the growth of the outward stock of Foreign Direct Investment (FDI) was observed in Poland and Lithuania. It is Poland and Estonia, however, that seemingly will climb on the ladder of IDP faster than Latvia and Lithuania. In all cases, these countries deal with higher dynamics of annual growth of Outward Foreign Direct Investment (OFDI) than Inward Foreign Direct Investment (IFDI), which suggests that all are at the third stage of IDI. However complex analysis reveals differences that shed new light on the progress of development paths of these BSR states.
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SANTOS, Eliane Barbosa, and Luiz Carlos Baldicero MOLION. "Um índice climático obtido da TSM do oceano pacífico e a variabilidade da precipitação em Alagoas." Revista Ambientale 2, no. 1 (December 23, 2017): 12. http://dx.doi.org/10.17648/ambientale.v2i1.87.

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Foi determinado um índice climático obtido da TSM do Pacífico, denominado Índice de Oscilação Interdecadal do Pacífico (IDP), com o objetivo de estudar a inter-relação entre o fenômeno El Niño-Oscilação Sul (ENOS) e a Oscilação Decadal do Pacífico (ODP), nas suas respectivas fases, e sua influência na variabilidade da precipitação no Estado de Alagoas. Para esse fim, foram utilizados dados da precipitação das estações meteorológicas de Alagoas, obtidas no site da Hidroweb. A série temporal do IDP foi correlacionada com a da ODP e do Índice de Oscilação Sul (IOS), mostrando relação direta entre IDP e ODP, e inversa entre IDP e IOS. A precipitação também foi empregada nas análises de correlação com IDP, ODP e IOS, mostrando que esses índices foram mais representativos na fase quente da ODP, e o IDP foi o que apresentou os maiores coeficientes de correlação nas duas fases da ODP.
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Shafiei, Nasir Ahmad, and K. Puttanna. "An investigation into the factors causing international development project failure in developing countries: Focus on Afghanistan." Journal of Project Management 6, no. 3 (2021): 157–70. http://dx.doi.org/10.5267/j.jpm.2021.2.002.

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This study aims to identify and evaluate the perception of major stakeholders on factors causing International Development Project (IDP) failure in the context of Afghanistan. The study adopts a quantitative cross-sectional survey research design. Thirty significant IDP failure factors included in the questionnaire were identified and shortlisted through literature reviews and validated by experts and IDP management practitioners. The survey was conducted using a structured questionnaire to investigate the most significant IDP failure factors, and various statistical tools were employed to evaluate the perception of the survey respondents. RII was used to examine the relative importance index of each failure factor. The failure factors were then grouped into five categories: Financial constraints, Ineffective recruitment, External forces, Project leadership, and Project management practices using EFA. The findings of the study will help the international development community and their IDP implementing partners, INGs and project management practitioners manage IDPs proactively and mitigate the risks of project failure. It will also contribute to the IDP management body of knowledge. The research is the first of its kind to examine the possible factors causing IDP failure in Afghanistan.
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Wrighton, Katharine H. "Phosphorylation regulates IDP folding." Nature Reviews Molecular Cell Biology 16, no. 2 (January 21, 2015): 66. http://dx.doi.org/10.1038/nrm3942.

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Kountchev, Roumen, Stuart Rubin, Mariofanna Milanova, and Roumiana Kountcheva. "Comparison of Image Decompositions Through Inverse Difference and Laplacian Pyramids." International Journal of Multimedia Data Engineering and Management 6, no. 1 (January 2015): 19–38. http://dx.doi.org/10.4018/ijmdem.2015010102.

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In this work, the Inverse Difference Pyramid (IDP) and its modification – the Reduced IDP (RIDP), are compared and evaluated with the famous Laplacian Pyramid (LP) for multi-level decomposition of digital images. The comparison comprises: the structures of LP and IDP, the image representation through LP and IDP in the pixel space and in the spectrum space of the Fourier transform, the efficiency of both transforms for the aims of the progressive image transfer, the LP and the IDP computation graphs and the evaluation of the computational complexity of the algorithms for the 3-level reduced LP and the 3-level reduced IDP. The influence of the quantization noise on both decompositions is also analyzed. On the basis of the comparison are outlined the basic advantages of the RIDP for pipeline image processing. The results obtained could be used for the design of coders for image compression, aimed at real-time applications, etc.
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Corre, Kevin, Olivier Barais, Gerson Sunyé, Vincent Frey, and Jean-Michel Crom. "Why can’t users choose their identity providers on the web?" Proceedings on Privacy Enhancing Technologies 2017, no. 3 (July 1, 2017): 75–89. http://dx.doi.org/10.1515/popets-2017-0029.

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Abstract Authentication delegation is a major function of the modern web. Identity Providers (IdP) acquired a central role by providing this function to other web services. By knowing which web services or web applications access its service, an IdP can violate the enduser privacy by discovering information that the user did not want to share with its IdP. For instance, WebRTC introduces a new field of usage as authentication delegation happens during the call session establishment, between two users. As a result, an IdP can easily discover that Bob has a meeting with Alice. A second issue that increases the privacy violation is the lack of choice for the end-user to select its own IdP. Indeed, on many web-applications, the end-user can only select between a subset of IdPs, in most cases Facebook or Google. In this paper, we analyze this phenomena, in particular why the end-user cannot easily select its preferred IdP, though there exists standards in this field such as OpenID Connect and OAuth 2? To lead this analysis, we conduct three investigations. The first one is a field survey on OAuth 2 and OpenID Connect scope usage by web sites to understand if scopes requested by websites could allow for user defined IdPs. The second one tries to understand whether the problem comes from the OAuth 2 protocol or its implementations by IdP. The last one tries to understand if trust relations between websites and IdP could prevent the end user to select its own IdP. Finally, we sketch possible architecture for web browser based identity management, and report on the implementation of a prototype.
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Johnson, A. L., Morgan J. Haugen, and Dori C. Woods. "Role for Inhibitor of Differentiation/Deoxyribonucleic Acid-Binding (Id) Proteins in Granulosa Cell Differentiation." Endocrinology 149, no. 6 (March 6, 2008): 3187–95. http://dx.doi.org/10.1210/en.2007-1659.

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Recent studies in the hen ovary have linked the initiation of granulosa cell differentiation at follicle selection to the alleviation of inhibitory MAPK signaling. The present studies assessed a role for individual inhibitor of differentiation (Id) protein isoforms as modulators of key transcriptional events occurring within granulosa cells at or immediately subsequent to differentiation. Findings from freshly collected granulosa cells collected at different stages of follicle development demonstrated a negative association between expression levels for Id2 mRNA compared with levels of Id1, Id3, and Id4. Elevated levels of Id2 are related to a differentiating/differentiated phenotype, whereas elevated Id1, Id3, and Id4 are associated with an undifferentiated phenotype. This negative relationship extends to cell signal transduction, because factors that promote inhibitory MAPK signaling (TGF-α and betacellulin) block expression of Id2 mRNA but increase levels of Id1, Id3, and Id4. Furthermore, overexpression of Gallus Id2 in cultured granulosa was found to significantly decrease levels of Id1, Id3, and Id4 mRNA but facilitate FSHR mRNA expression and, importantly, initiate LHR mRNA expression plus LH-induced progesterone production. Finally, knockdown studies using small interfering RNA specific for Id2 revealed reduced expression of FSHR and LHR mRNA and attenuated FSH- and LH-induced levels of StAR and p450 cholesterol side-chain cleavage enzyme mRNA plus progesterone production. Collectively, these data demonstrate that Id2 expression is both sufficient and necessary for increasing LHR expression and, as a result, promoting gonadotropin-induced differentiation in hen granulosa cells subsequent to follicle selection.
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SOUSA, Gioto Ghiarone Terto e., Karina Rodrigues dos SANTOS, José Elivalto Guimarães CAMPELO, Marcelo Richelly Alves de OLIVEIRA, Luanna Chácara PIRES, Rodrigo Junqueira PEREIRA, Rogério Paes Ribeiro de SOUSA, and Severino Cavalcante de SOUSA JÚNIOR. "Fatores ambientais e parâmetros genéticos para características reprodutivas de fêmeas Nelore na região meio norte do Brasil." Revista Brasileira de Saúde e Produção Animal 16, no. 2 (June 2015): 290–99. http://dx.doi.org/10.1590/s1519-99402015000200003.

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O estudo foi conduzido para avaliar a idade ao primeiro parto (IPP) e o intervalo de partos (IDP) em fêmeas da raça Nelore utilizando 23.066 registros de IPP e IDP de fêmeas criadas em regime de pasto nos estados do Maranhão e Piauí no período de 1976 a 2012. As análises foram realizadas utilizando modelo animal uni e bicaracterísticas para IPP e IDP. As médias obtidas e os coeficientes de variação para as características de idade ao primeiro parto foram 1252,77±125 dias (41,76 meses) a 10,56%; intervalo de partos 591,729±149,91 dias (19,72 meses) a 38,74%, respectivamente. Foram estimados parâmetros genéticos em análise unicaracterística, sendo obtidos valores de herdabilidade em torno de 0,026 e 0,006 para IPP e IDP, respectivamente. A estimativa de repetibilidade para as características IDP em análise unicaracterística apresentou-se, de forma geral, com baixa magnitude 0,025. Na mesma ordem, para análise bicaracterística, as herdabilidades foram de 0,03 e 0,06 para IPP e IDP, e o coeficiente de repetibilidade estimado de 0,14, respectivamente. As correlações genéticas entre as características reprodutivas (IPP e IDP) observadas neste trabalho foram iguais a 0,06. O desempenho reprodutivo do rebanho estudado, para as condições de clima tropical, pode ser considerado satisfatório, estando em acordo com os parâmetros encontrados por outros autores em diferentes regiões.
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Kashirina, Alena, Alena Gavrina, Artem Mozherov, Dmitriy Kozlov, Daria Kuznetsova, Ekaterina Vorotelyak, Elena Zagaynova, Ekaterina Kalabusheva, and Aleksandra Kashina. "FLIM for Evaluation of Difference in Metabolic Status between Native and Differentiated from iPSCs Dermal Papilla Cells." Cells 11, no. 17 (September 1, 2022): 2730. http://dx.doi.org/10.3390/cells11172730.

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iPSCs and their derivatives are the most promising cell sources for creating skin equivalents. However, their properties are not fully understood. In addition, new approaches and parameters are needed for studying cells in 3D models without destroying their organization. Thus, the aim of our work was to study and compare the metabolic status and pH of dermal spheroids created from dermal papilla cells differentiated from pluripotent stem cells (iDP) and native dermal papilla cells (hDP) using fluorescence microscopy and fluorescence lifetime imaging microscopy (FLIM). For this purpose, fluorescence intensities of NAD(P)H and FAD, fluorescence lifetimes, and the contributions of NAD(P)H, as well as the fluorescence intensities of SypHer-2 and BCECF were measured. iDP in spheroids were characterized by a more glycolytic phenotype and alkaline intra-cellular pH in comparison with hDP cells. Moreover, the metabolic activity of iDP in spheroids depends on the source of stem cells from which they were obtained. So, less differentiated and condensed spheroids from iDP-iPSDP and iDP-iPSKYOU are characterized by a more glycolytic phenotype compared to dense spheroids from iDP-DYP0730 and iDP-hES. FLIM and fluorescent microscopy in combination with the metabolism and pH are promising tools for minimally invasive and long-term analyses of 3D models based on stem cells.
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Vanderford, Nathan L., Teresa M. Evans, L. Todd Weiss, Lindsay Bira, and Jazmin Beltran-Gastelum. "Use and effectiveness of the Individual Development Plan among postdoctoral researchers: findings from a cross-sectional study." F1000Research 7 (October 25, 2018): 1132. http://dx.doi.org/10.12688/f1000research.15610.2.

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The individual development plan (IDP) is a career planning tool that aims to assist PhD trainees in self-assessing skills, exploring career paths, developing short- and long-term career goals, and creating action plans to achieve those goals. The National Institutes of Health and many academic institutions have created policies that mandate completion of the IDP by both graduate students and postdoctoral researchers. Despite these policies, little information exists regarding how widely the tool is used and whether it is useful to the career development of PhD trainees. Herein, we present data from a multi-institutional, online survey on the use and effectiveness of the IDP among a group of 183 postdoctoral researchers. The overall IDP completion rate was 54% and 38% of IDP users reported that the tool was helpful to their career development. Positive relationships with one’s advisor, confidence regarding completing training, trainees’ confidence about their post-training career, and a positive experience with institutional career development resources are associated with respondents’ perception that the IDP is useful for their career development. We suggest that there is a need to further understand the nuanced use and effectiveness of the IDP in order to determine how to execute the use of the tool to maximize trainees’ career development.
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Thompson, Sheri. "VOCATIONAL ASSESSMENT AND INDIVIDUAL DEVELOPMENT PLANNING IN DIVERSITY-FOCUSED UNDERGRADUATE MENTORSHIP." Innovation in Aging 6, Supplement_1 (November 1, 2022): 859. http://dx.doi.org/10.1093/geroni/igac059.3074.

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Abstract The UC San Diego MADURA Mentorship Program, funded the National Institute on Aging, strives to improve diversity in Aging/Alzheimer’s Disease and Related Dementias (ADRD) research and clinical practice. Goals include improved academic success of undergraduate URM trainees, and facilitating graduate/medical school applications and entry into Aging/ADRD research or clinical careers. Mentees receive paid research experience, training, Program and lab-based faculty supervision, peer support, seminars, and professional development opportunities. To enhance educational and career planning, MADURA incorporated Individual Development Plan (IDP) use, in 2022. IDP training by a Career Services presenter was followed by interactive IDP completion during small group break-outs, with ongoing revisions occurring throughout the quarter. Further, all trainees were offered formal vocational assessment (Strong Interest Inventory®, College Edition). 21 trainees participated and some engaged in individual 30-minute feedback sessions. All mentors were asked to incorporate IDP and vocational assessment discussions into year-end professional development meetings with mentees. Data to be presented includes: Student evaluation of IDP training; prior vocational assessment access; student and mentor ratings of IDP and vocational assessment feasibility, utility and satisfaction; and cohort vocational profile characteristics. Discussion includes implementation challenges, benefits and limitations of IDP and vocational assessment use, and future research suggestions.
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Vanderford, Nathan L., Teresa M. Evans, L. Todd Weiss, Lindsay Bira, and Jazmin Beltran-Gastelum. "A cross-sectional study of the use and effectiveness of the Individual Development Plan among doctoral students." F1000Research 7 (July 5, 2018): 722. http://dx.doi.org/10.12688/f1000research.15154.2.

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Background: The Individual Development Plan (IDP) was introduced as a tool to aid in career planning for doctoral trainees. Despite the National Institutes of Health and academic institutions creating policies that mandate the use of IDPs, little information exists regarding the use and effectiveness of the career planning tool. Methods: We conducted a multi-institutional, online survey to measure IDP use and effectiveness. The survey was distributed to potential respondents via social media and direct email. IDP survey questions were formatted using a five-point Likert scale (strongly agree, agree, neutral, disagree and strongly disagree). For data analysis purposes, responses were grouped into two categories (agree versus does not agree/disagree). The data were summarized as one-way frequencies and the Pearson chi-square test was used to determine the statistical significance of univariate associations between the survey variables and an outcome measure of the effectiveness of the IDP. Results: Among all respondents, fifty-three percent reported that they are required to complete an IDP while thirty-three percent reported that the tool is helpful to their career development. Further, our data suggests that the IDP is most effective when doctoral students complete the tool with faculty mentors with whom they have a positive relationship. Respondents who are confident about their career plans and who take advantage of career development resources at their institution are also more likely to perceive that the IDP is useful for their career development. Conclusion: Given the nuanced use and effectiveness of the IDP, we call for additional research to characterize the overall use and effectiveness of the IDP and to determine whether there are unintended negative consequences created through the use of the tool. Furthermore, we recommend an enhancement of career development infrastructure that would include mentorship training for faculty in order to provide substantially more career planning support to trainees.
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Vanderford, Nathan L., Teresa M. Evans, L. Todd Weiss, Lindsay Bira, and Jazmin Beltran-Gastelum. "Use and effectiveness of the Individual Development Plan among postdoctoral researchers: findings from a cross-sectional study." F1000Research 7 (July 25, 2018): 1132. http://dx.doi.org/10.12688/f1000research.15610.1.

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The individual development plan (IDP) is a career planning tool that assists PhD trainees in self-assessing skills, exploring career paths, developing short- and long-term career goals, and creating action plans to achieve those goals. The National Institutes of Health and many academic institutions have created policies that mandate completion of the IDP by both graduate students and postdoctoral researchers. Despite these policies, little information exists regarding how well the tool is used and whether it is useful to the career development of PhD trainees. Herein, we present data from a multi-institutional, online survey on the use and effectiveness of the IDP among a group of 183 postdoctoral researchers. The overall IDP completion rate was 54% and 38% of IDP users reported that the tool was helpful to their career development. Positive relationships with one’s advisor, confidence regarding completing training, one’s confidence about their post-training career, and a positive experience with institutional career development resources are associated with respondents’ perception that the IDP is useful for their career development. We suggest that there is a need to further understand the nuanced use and effectiveness of the IDP in general, to determine how to execute the use of the tool to maximize trainees’ career development, and to generally enhance the career development support for PhD trainees.
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Knell, Sebastian C., Brian Park, Benjamin Voumard, and Antonio Pozzi. "Ex vivo study of the intradiskal pressure in the C6-7 intervertebral disk after experimental destabilization and distraction-fusion of the C5-C6 vertebrae in canine cadaveric specimens." American Journal of Veterinary Research 82, no. 12 (December 2021): 1003–12. http://dx.doi.org/10.2460/ajvr.20.12.0218.

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Abstract OBJECTIVE To evaluate intradiskal pressure (IDP) in the C6-7 intervertebral disk (IVD) after destabilization and distraction-fusion of the C5-C6 vertebrae. SAMPLE 7 cadaveric C4-T1 vertebral specimens with no evidence of IVD disease from large-breed dogs. PROCEDURES Specimens were mounted in a custom-made 6 degrees of freedom spinal loading simulator so the C5-C6 and C6-C7 segments remained mobile. One specimen remained untreated and was used to assess the repeatability of the IDP measurement protocol. Six specimens underwent 3 sequential configurations (untreated, partial diskectomy of the C5-6 IVD, and distraction-fusion of the C5-C6 vertebrae). Each construct was biomechanically tested under neutral, flexion, extension, and right-lateral bending loads. The IDP was measured with a pressure transducer inserted into the C6-7 IVD and compared between the nucleus pulposus and annulus fibrosus and across all 3 constructs and 4 loads. RESULTS Compared with untreated constructs, partial diskectomy and distraction-fusion of C5-C6 decreased the mean ± SD IDP in the C6-7 IVD by 1.3 ± 1.3% and 0.8 ± 1.3%, respectively. During motion, the IDP remained fairly constant in the annulus fibrosus and increased by 3.8 ± 3.0% in the nucleus pulposus. The increase in IDP within the nucleus pulposus was numerically greatest during flexion but did not differ significantly among loading conditions. CONCLUSIONS AND CLINICAL RELEVANCE Distraction-fusion of C5-C6 did not significantly alter the IDP of healthy C6-7 IVDs. Effects of vertebral distraction-fusion on the IDP of adjacent IVDs with degenerative changes, such as those in dogs with caudal cervical spondylomyelopathy, warrant investigation.
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Gudavalli, M. R., T. Potluri, G. Carandang, R. M. Havey, L. I. Voronov, J. M. Cox, R. M. Rowell, et al. "Intradiscal Pressure Changes during Manual Cervical Distraction: A Cadaveric Study." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/954134.

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The objective of this study was to measure intradiscal pressure (IDP) changes in the lower cervical spine during a manual cervical distraction (MCD) procedure. Incisions were made anteriorly, and pressure transducers were inserted into each nucleus at lower cervical discs. Four skilled doctors of chiropractic (DCs) performed MCD procedure on nine specimens in prone position with contacts at C5 or at C6 vertebrae with the headpiece in different positions. IDP changes, traction forces, and manually applied posterior-to-anterior forces were analyzed using descriptive statistics. IDP decreases were observed during MCD procedure at all lower cervical levels C4-C5, C5-C6, and C6-C7. The mean IDP decreases were as high as 168.7 KPa. Mean traction forces were as high as 119.2 N. Posterior-to-anterior forces applied during manual traction were as high as 82.6 N. Intraclinician reliability for IDP decrease was high for all four DCs. While two DCs had high intraclinician reliability for applied traction force, the other two DCs demonstrated only moderate reliability. IDP decreases were greatest during moving flexion and traction. They were progressevely less pronouced with neutral traction, fixed flexion and traction, and generalized traction.
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Silva-Arias, Adriana Carolina, Jaime Andrés Sarmiento-Espinel, and Laura Victoria González-Cogollos. "Gender Inequalities in Academic Achievement among Internally Displaced children in Colombia." Revista Latinoamericana de Ciencias Sociales Niñez y Juventud 18, no. 2 (May 14, 2020): 1–19. http://dx.doi.org/10.11600/1692715x.18213.

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Using 2015 data of the Colombia Demographic and Health Survey, we investigated the incidence of belonging to a household with an Internally Displaced Person (IDP) on the likelihood of grade retention by sex. Particularly, a bivariate logistic regression was used to identify the correlation between families with IDP and children’s gender on the probability of repeating a school year. Boys’ were negatively affected when they live in an IDP household. Also, boys had a higher likelihood of repeating a grade. We need to know how to act upon the social determinants that create social gaps and disadvantages across IDP, but also, to align with Sustainable Development Goals to eliminate gender inequalities.
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Sané, Seydou, and Pascaline Abo. "Transactional leadership and success of international development projects (IDP): mediating effects of cooperative style to conflict resolution and team potency." Management Research Review 44, no. 12 (October 11, 2021): 1623–38. http://dx.doi.org/10.1108/mrr-09-2020-0575.

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Purpose This study aims to examine the mediating role of cooperative style to conflict resolution and team potency in the relationship between transactional leadership style and the success of international development projects (IDP). The study draws on full range leadership theory and contextualizes transactional leadership style to the IDP environment. Design/methodology/approach A questionnaire survey was administered to a convenience sample of 111 IDP managers in Benin. The data obtained from the survey were subjected to principal component analysis using the SPSS and confirmatory factor analysis using XLSTAT-PLSM. The research hypotheses are tested according to the partial least squares method. Findings The hypothesis test shows that transactional leadership has a direct and indirect positive influence (through team potency) on the success of IDP. Contrary to the cooperative style of conflict resolution, team potency plays a partial mediating role in the relationship between transactional leadership and the success of IDP. Also, considering the effect of the specific dimensions of transactional leadership on the success of IDP, only the “active management by exception” dimension influences directly and indirectly (through team potency) on the latter. Practical implications As a result, this research is of great value to IDP managers who are aware of the positive consequences associated with transactional leadership without knowing the role played by its dimensions. Indeed, it provides them with information necessary to identify the appropriate transactional leadership behaviors to improve the success of projects. Originality/value The relevance of this study is to consider team potency as intermediary mechanisms between transactional leadership and the success of IDP and examine the effect of the dimensions of transactional leadership on the success of IDP by integrating the mediating action of team potency. Besides, this research highlights a mechanism through which transactional leadership influences the success of IDPs and shows that the use of the construct of transactional leadership rather than its specific dimensions does not capture the specificities of the mechanism that links transactional leadership and its consequences.
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Cheah, Jonathan W., Grant H. Cabell, Nicholas A. Bonazza, and Dean C. Taylor. "Use of an Individualized Development Plan to Identify Career Development Needs in Prospective Orthopaedic Sports Medicine Fellows." Orthopaedic Journal of Sports Medicine 9, no. 12 (December 1, 2021): 232596712110591. http://dx.doi.org/10.1177/23259671211059125.

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Background: Mentorship is a key aspect of leadership development for orthopaedic surgeons, but there are few formalized mentorship programs in medical training. The individualized development plan (IDP) is a tool that potentially improves mentorship opportunities through identifying specific competency deficiencies and facilitating communication with mentors. Purpose: To assess the views of prospective orthopaedic surgery sports medicine fellows on the skills necessary for career development and the utility of an IDP for longitudinal career mentorship during a sports medicine fellowship. Study Design: Cross-sectional study. Methods: Candidates who interviewed for an orthopaedic surgery sports medicine fellowship voluntarily completed an anonymous IDP as well as a survey to assess their perceptions of the IDP tool to define their career goals and its use for longitudinal mentorship. The IDP included quantitative and qualitative responses for the self-assessment of multiple skill domains (general research, teaching, professional, interpersonal, leadership, and management) using a 5-point Likert scale (1 = needs improvement, 5 = highly proficient). Quantitative results were analyzed using analysis of variance and Student t test. Results: A total of 25 candidates completed the IDP and survey. The mean ± standard deviation composite score of all skill domains was 3.62 ± 0.91. The candidates’ greatest deficit was in grant writing (2.28 ± 0.94; P < .01), while their greatest strength was getting along with others (4.52 ± 0.65; P < .01). Candidates identified, as short-term goals, obtaining a fellowship training position, completion of research/academic projects, and improvement of surgical skills; their common long-term goals included having a role in an academic institution, professional society, and/or research and innovation environment. The majority of participants agreed that the IDP is a valuable tool to characterize career and personal goals (74%) and facilitate longitudinal fellowship mentorship (83.3%). Conclusion: The majority of candidates valued the IDP for their short- and long-term goals. Program implementation of an IDP could be beneficial in allowing trainees to effectively identify areas of weakness and strengths while facilitating efficient communication of these needs to mentors.
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Li, Jia-Qi, Wai-Hang Kwong, Yuk-Lam Chan, and Masato Kawabata. "Comparison of In Vivo Intradiscal Pressure between Sitting and Standing in Human Lumbar Spine: A Systematic Review and Meta-Analysis." Life 12, no. 3 (March 20, 2022): 457. http://dx.doi.org/10.3390/life12030457.

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Background: Non-specific low back pain (LBP) is highly prevalent today. Disc degeneration could be one of the causes of non-specific LBP, and increased intradiscal pressure (IDP) can potentially induce disc degeneration. The differences in vivo IDP in sitting and standing postures have been studied, but inconsistent results have been reported. The primary objective of this systematic review is to compare the differences in vivo IDP between sitting and standing postures. The secondary objective of this review is to compare effect size estimates between (1) dated and more recent studies and (2) healthy and degenerated intervertebral discs. Methods: An exhaustive search of six electronic databases for studies published before November 2021 was conducted. Articles measuring in vivo IDP in sitting and standing postures were included. Two independent researchers conducted the screening and data extraction. Results: Ten studies that met the inclusion criteria were included in the systematic review, and seven studies with nine independent groups were included in meta-analyses. The sitting posture induces a significantly higher IDP on the lumbar spine (SMD: 0.87; 95% CI = [0.33, 1.41]) than the standing posture. In studies published after 1990 and subjects with degenerated discs, there are no differences in vivo IDP between both postures. Conclusions: Sitting causes higher loads on the lumbar spine than standing in the normal discs, but recent studies do not support this conclusion. Furthermore, the degenerated discs showed no difference in IDP in both postures.
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Hill, R. "IDP LIVELIHOODS: Idp Livelihoods and Personal Security: Case Studies from Colombia and Sudan." Refugee Survey Quarterly 25, no. 2 (January 1, 2006): 40–59. http://dx.doi.org/10.1093/rsq/hdi0124.

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Chang, Ming-Jin. "The Bcl-2—IP3 Receptor Interaction As a Novel Target for Therapeutics in Myeloma." Blood 120, no. 21 (November 16, 2012): 4011. http://dx.doi.org/10.1182/blood.v120.21.4011.4011.

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Abstract Abstract 4011 The anti-apoptotic Bcl-2 (B-cell lymphoma 2) protein was first identified in follicular lymphoma, where the Bcl-2 gene was dysregulated as a result of chromosomal translocation. The anti-apoptotic activity of Bcl-2 can be attributed to two mechanisms conferred by structurally distinct domains. First, the BH domains 1–3 of Bcl-2 dimerize with pro-apoptotic members of the Bcl-2 family, such as Bax and Bak, and maintain mitochondrial integrity. Small molecules targeting these domains on Bcl-2 (e.g. ABT-737 and ABT-263/Navitoclax®) are under clinical evaluation. A less explored activity of Bcl-2 is that its BH4 domain functionally interacts with the IP3 receptor located on the endoplasmic reticulum (ER) membrane, the major organelle involved in regulating calcium homeostasis. Through this interaction, Bcl-2 inhibits IP3 receptor channel opening and prevents excessive calcium release from ER that can be harmful to cells. Our strategy is to disrupt the Bcl-2—IP3 receptor interaction to induce cell death in lymphoid malignant cells. Previously, our group has shown that an IP3 receptor derived peptide, or IDP, blocks the Bcl-2—IP3 receptor interaction and thereby induces elevation of cytosolic calcium in lymphoma cell lines. A modified version of the peptide—IDP-DD/AA, with an asparaginase cleavage site removed, is more potent in inducing calcium elevation as well as apoptosis in primary chronic lymphocytic leukemia (CLL) cells. Concentrations of the IDP-DD/AA peptide that killed CLL cells did not affect the viability of normal lymphocytes, suggesting a therapeutic window. We further exploited the cytotoxic activities in a panel of leukemia/lymphoma/myeloma cell lines and found that over 60% of myeloma cell lines tested were sensitive to the IDP-DD/AA peptide but not to the control peptide. Furthermore, in the sensitive myeloma cell lines treated with the IDP-DD/AA peptide, high amplitude cytosolic calcium elevation preceded caspase-3 activation and apoptotic morphology, suggesting the involvement of a calcium-mediated intrinsic apoptotic pathway. The in vivo anti-tumor activity of the IDP peptide was assessed in a myeloma xenograft model. Subcutaneous tumors were established in nude mice using the human myeloma cell line, NCI-H929. Randomly grouped mice treated by in-tumor injection of the IDP-DD/AA peptide showed prominent inhibition of tumor growth compared to saline-injected control. One of three mice treated with the IDP-DD/AA peptide showed no visible sign of tumor at the end of treatment. The data proffer promise of therapeutic use of the IDP peptide in myeloma disease. The effect of combinatory treatment of the IDP-DD/AA peptide and current anti-myeloma drugs (Bortezomib/Valcade®, doxorubicin/Adriamycin®, melphalan) were evaluated. Co-treatment of the myeloma cell line NCI-H929 cells with the IDP-DD/AA peptide and each one of the three anti-myeloma drugs induced synergistic cytotoxicity with combinatory indices (CI) less than 1. The data suggest that the IDP-DD/AA peptide augments cell killing activity of current chemotherapy drugs. In conclusion, the IDP-DD/AA peptide represents a novel anti-cancer agent that targets the anti-apoptotic Bcl-2 protein. The peptide exhibits both in vitro and in vivo anti-myeloma activity. Moreover, the IDP-DD/AA peptide can function as a single agent (in myeloma or CLL) as well as in combination with current anti-myeloma chemotherapy drugs. Disclosures: No relevant conflicts of interest to declare.
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Vanderford, Nathan L., Teresa M. Evans, L. Todd Weiss, Lindsay Bira, and Jazmin Beltran-Gastelum. "A cross-sectional study of the use and effectiveness of the Individual Development Plan among doctoral students." F1000Research 7 (June 11, 2018): 722. http://dx.doi.org/10.12688/f1000research.15154.1.

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Background: The Individual Development Plan (IDP) was introduced as a tool to aid in career planning for doctoral trainees. Despite the National Institutes of Health and academic institutions creating policies that mandate the use of IDPs, little information exists regarding the actual use and effectiveness of the career planning tool. Methods: We conducted a multi-institutional, online survey to measure IDP use and effectiveness. The survey was distributed to potential respondents via social media and direct email. IDP survey questions were formatted using a five-point Likert scale (strongly agree, agree, neutral, disagree and strongly disagree). For data analysis purposes, responses were grouped into two categories (agree versus does not agree/disagree). The data were summarized as one-way frequencies and the Pearson Chi-square test was used to determine statistical significance. Results: Usage of the IDP among doctoral students was low and the tool produces minimal effectiveness with regard to the perception of whether it is helpful to one’s career development. Further, our data suggests that the IDP is most effective when doctoral students complete the tool with faculty mentors with whom they have a positive relationship. Respondents who are confident about completing their doctoral training and their post-training career plans, and who take advantage of career development resources at their institution are also more likely to perceive that the IDP is useful for their career development. Conclusion: Given the nuanced use and effectiveness of the IDP, we call for more research to determine why IDP use and effectiveness is low, exactly how IDPs are being used, and whether there are unintended negative consequences created through the use of the tool. Furthermore, we recommend an enhancement of career development infrastructure that would include mentorship training for faculty in order to provide substantially more career planning support to doctoral trainees.
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Mamokhere, John. "Leaving no one behind in a participative integrated development planning process in South Africa." International Journal of Research in Business and Social Science (2147- 4478) 11, no. 10 (December 31, 2022): 277–91. http://dx.doi.org/10.20525/ijrbs.v11i10.2238.

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The purpose of this study is to explore the IDP process for improved public participation and thereafter assess the barriers to the design and implementation of the IDP. The IDP process was developed to improve strategic planning and ensure that no one is left behind at the grassroots. This was done by promoting public participation in municipal affairs. Many South African municipalities have been struggling to use the IDP process to improve public participation. A mixed-methods approach to investigate the participative IDP process and barriers, using the Greater Tzaneen Municipality (GTM) as a case study was adopted. The methodology included 400 respondents who were chosen through a probability sampling technique and probed to complete the online survey using a closed-ended questionnaire guide, and 10 respondents were also chosen through a non-probability sampling technique and were face-to-face interviewed using a semi-structured interview guide. The key results revealed that poor public participation exists in the study area due to a lack of encouragement from responsible authorities. Many barriers hinder the effective design and implementation of the participative IDP process, such as protests, working in silos, a lack of institutional resources to address the competing needs of communities, and a lack of transparency, accountability, and consultation. Lastly, the lack of oversight by the municipality in the adoption of e-participation has been discovered as a barrier to the design and implementation of participative IDP process during the COVID-19 pandemic. The study concludes by providing a few recommendations to enhance participative IDP process. The GTM should at all times uphold democratic principles by ensuring active and effective public participation, transparency, and accountability in municipal affairs. South African municipalities, especially GTM, should develop innovative institutional and organizational skills to make better use of their resources, solve socioeconomic barriers, and enhance service delivery.
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Resnick, Michael B., Fonda Davis Eyler, Robert M. Nelson, Donald V. Eitzman, and Richard L. Bucciarelli. "Developmental Intervention for Low Birth Weight Infants: Improved Early Developmental Outcome." Pediatrics 80, no. 1 (July 1, 1987): 68–74. http://dx.doi.org/10.1542/peds.80.1.68.

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This prospective longitudinal study was designed to evaluate the effects of a multidisciplinary infant development program (IDP) on the mental and physical development of low birth weight infants (&lt;1,800 g). Infants in the neonatal intensive care were randomly assigned to the IDP or to traditional care (control group). IDP infants received developmental interventions in the hospital and at home through the first 2 years of life. Counseling and parenting education were provided to their parents during this same period. The control group received all the postnatal care and referrals customarily given in traditional care. Both IDP and control infants were enrolled in an independent follow-up program, which used the Bayley Scales of Infant Development in a blind evaluation design. The IDP group had a significantly lower incidence of developmental delay (P &lt; .05) and scored significantly higher than the control group (P &lt; .05) on mean mental and physical indices at 12 and 24 months of adjusted age.
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Adeeva, Tatiana, Inna Tikhonova, and Svetlana Khazova. "VARIANTS OF INWARD DISORDER PATTERN AND SELF-AWARENESS FEATURES AMONG ELEMENTARY SCHOOL CHILDREN WITH DIFFERENT DYSONTOGENESIS FORMS." SOCIAL WELFARE: INTERDISCIPLINARY APPROACH 1, no. 9 (December 9, 2019): 120. http://dx.doi.org/10.21277/sw.v1i9.456.

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<p>This study explored variants of inward disorder pattern (IDP) among elementary school children with different dysontogenesis forms. IDP is considered a complex integrative construct that affects I-concept development and is significant for an individual’s successful social adaptation. The sample consisted of 84 participants – elementary school children with visual, hearing, speech impairments, and mental development disorder. Their average age is 9. The interview was conducted individually.</p><p>We identified a number of specificities in IDP components content depending on a dysontogenesis form. These features are determined by both an impairment itself and component ratios where those between the physical-sensitive, cognitive, and motivational ones are of the greatest significance. Other IDP determinants are such complex self-awareness indices as a level of one’s traits awareness and self-perception in a context of social relationships. The study results suggest three variants of IDP for the moment.</p>
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Craven, Rachel, and Lyn Shelton. "Emotional problems and intellectual disability: comparing groups with and without forensic involvement." Journal of Intellectual Disabilities and Offending Behaviour 11, no. 4 (September 21, 2020): 239–48. http://dx.doi.org/10.1108/jidob-05-2020-0010.

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Purpose Individuals with intellectual disability (ID) are known to experience increased emotional and behavioural concerns. The study aims to assess whether detained ID patients with a forensic history (IDPF) have increased difficulty managing their impulse control in comparison to detained ID patients without a forensic history (IDP). Using the externalising behaviour problems (EBP) subscale of the EPS, the study aims to compare the differences between the IDFP and IDP groups. Design/methodology/approach A total of 60 patients with ID detained under the Mental Health Act 1983 (Revised 2007) were assessed using the behaviour rating scale of the EPS. The outcome scores of the EBP were used to examine any observed differences between the scores of forensically involved patients [n = 34] and those without a forensic history [n = 26]. It was hypothesised that patients with a forensic history would display higher scoring on externalised behavioural problems (EBP) than patients without such a history. Findings Non-parametric testing revealed that there were no significant differences in EBP scoring between the two sample groups. These findings indicate that, for patients in the present study, no differences were detected in the presentation of these two distinct groups. In fact, with the exception of the verbal aggression subscale of the EBP, the other three subscales (physical aggression, non-compliance and hyperactivity) show that actually the IDP group displayed the higher ranked means in these subscales when compared with the forensically involved group. Originality/value These results indicate possible increased treatment needs within the IDP group and question whether offending history is necessarily a reliable predictor of ongoing hostility and behavioural concerns within similar inpatient services.
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Wang, Jian, and Guoliang Lin. "A New Concept of Intensity Data Area and Its Effect on the Parameter Determination of Historical Earthquakes." Seismological Research Letters 91, no. 5 (July 8, 2020): 2685–94. http://dx.doi.org/10.1785/0220200071.

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Abstract In ancient China, the government annals provided abundant historical earthquake records, which lasted more than 2000 yr. In some cases, the earthquake damage descriptions from the high-tier government annals are so concise that the specific place names were omitted, even the names of towns where the damage might have actually occurred. The intensity data point (IDP) was assigned to the capital town of the high-tier government, which might lead to large uncertainties in the historical earthquake parameters. A new concept of intensity data area (IDA) is proposed specifically to deal with this issue. An approach on how to convert the IDA to an IDP, based on nonseismological information, is described. In this process, we emphasize the effectiveness of field trips to investigate local features, such as natural environment, population distribution, historical administration zoning, and so forth. As case examples, two historical earthquakes in the Ming Dynasty are analyzed. The documentations of both earthquakes have a common problem, in that some damage was described with the name of the highest-tier local government (Fu); this led to the dispute about the parameter of historical earthquakes. With the proposed method, the IDA for Fu is successfully converted to an IDP at the suitable site. This is the key step to solve the dispute and reduce the parameter uncertainty. Our results have revealed that the parameters of both case earthquakes in the latest edition of the catalog (“The Catalog of Chinese Historical Strong Earthquakes (2300 B.C.–A.D. 1911)”) were wrong (Min et al., 1995). It is noteworthy that the latest edition of the catalog is currently in common use. To avoid the misuse of the catalog, it is better that the parameters in the catalog be restudied, especially for those labeled with large uncertainties.
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43

Чернятин and S. Chernyatin. "Conceptual Framework for Methodology of Vertically Integrated Company’s Innovation Development Program Formation." Administration 3, no. 4 (December 10, 2015): 75–83. http://dx.doi.org/10.12737/16700.

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The large businesses role in the current Russian and world’s innovation activity practice is considered in this paper. Priority guidelines for the improvement of innovation development programs (IDP) technology relating to vertically integrated companies have been identified in the frame of Russian partially governmentowned companies’ IDP analysis. In particular, key principles for corporate IDP formation, which defined requirements to this document, as well as methods for their accounting, have been presented. An integrating stage of the corporate IDP formation process, consisting in the development of a specific methodological approach to the implementation of the above principles and requirements in the frame of selected methods for their accounting has been considered in details.
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44

Fedorenko, O. "THE THEORETICAL MODEL OF SOCIAL INTEGRATION OF INTERNALLY DISPLACED PERSONS IN THE COMMUNITY." Bulletin of Taras Shevchenko National University of Kyiv. Social work, no. 3 (2018): 17–22. http://dx.doi.org/10.17721/2616-7786.2018/3-1/4.

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The article is devoted to the problem of social integration of internally displaced persons into the host community. Despite the numerous studies currently being conducted in Ukraine: sociological, psychological, demographic, etc., the conditions for the integration of internally displaced persons to host communities remain insufficiently learned. In our opinion, this impedes the systematic solution and forecasting of social integration problems at the national, regional and local levels, as well as the process of developing an optimal social policy in relation to the migrating person. Therefore, the purpose of the article is to analyze scientific research in this area and develop a theoretical model for the integration of internally displaced persons in the community. We have considered the last researches on the stated problems and have specified the content and the structure of the process of integration of IDP. On the basis of methodological analysis, the theoretical model of social integration of internally displaced persons in the community has been developed. The theoretical model of social integration of the IDP in the community is developed, which consists of four components: sociopsychological, cultural and communicative, socio-economic and socio-political. These components affect the degree of social integration of IDP and their social well-being. The scheme of the IDP integration process into the community is specified. The scheme has three levels of structure: the level of community-based IDP, the level of perception of the IDP community population and their adoption, and the administrative political level of creating the necessary conditions for successful social integration of the IDP.
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45

Hoyos-Bachiloglu, Rodrigo, Cristian Sotomayor F., and Cecilia Poli H. "Inmunodeficiencia combinada severa: es tiempo de su detección precoz." Andes Pediatrica 90, no. 6 (December 11, 2019): 581. http://dx.doi.org/10.32641/andespediatr.v90i6.1310.

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Las inmunodeficiencias primarias (IDP) son un conjunto de cerca de 350 enfermedades genéticas que afectan el funcionamiento del sistema inmunológico. Los avances en diagnóstico genético han permitido describir nuevos defectos en el sistema inmune, ampliando el espectro de manifestaciones de las IDP más allá de la susceptibilidad a infecciones. Aunque la mayoría de las IDP se presentan con infecciones recurrentes u oportunistas, un subgrupo puede presentarse por el desarrollo precoz de fenómenos autoinflamatorios, tumorales y, paradojalmente, la coexistencia de autoinmunidad e inmunodeficiencia en un mismo paciente. Al igual que sus manifestaciones clínicas, la severidad de las IDP es variable. La inmunodeficiencia combinada severa (IDCS), caracterizada por una falla en la respuesta humoral y celular, es una de las formas más graves de IDP y el único tratamiento curativo disponible en Latino-América es el trasplante de precursores hematopoyéticos. La IDCS es 100% letal durante los dos primeros años de vida si no se diagnostica y trata oportunamente. Por el contrario, si se trasplantan precozmente, estos pacientes pueden alcanzar una sobrevida normal. Pese a los avances en el diagnóstico de IDP que se han observado en nuestro país en los últimos años, los recursos diagnósticos no se encuentran disponibles en todas las regiones, lo que dificulta el reconocimiento temprano de la IDCS y otras IDP en grandes áreas del país. El objetivo de esta actualización es revisar conceptos generales sobre la fisiopatología de la IDCS, diagnóstico, manejo inicial y plantear la necesidad de la implementación del tamizaje neonatal de IDCS en Chile.
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46

Martina, Camille A., Janice L. Gabrilove, Naomi Luban, and Cecilia M. P. Sutton. "2502 The need for an evidence-based CTS specific IDP for early career training and for a long-term and sustainable career in clinical translational sciences." Journal of Clinical and Translational Science 2, S1 (June 2018): 61–62. http://dx.doi.org/10.1017/cts.2018.230.

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OBJECTIVES/SPECIFIC AIMS: To establish a conceptual framework to develop a CTS-IDP with data analytics, and an e-Learning Faculty Development Guide on best practices and use of the IDP over the CTS academic life-course. METHODS/STUDY POPULATION: To accomplish our goal, we propose the following methods: (1) an online survey, using a convenience sample of the 24 KL2 CTSA IDP Collaborative members (conducted in 2017), to assess perceived needs for a universal CTS-IDP, current IDP practices, barriers to IDP use, and to discern and align each CTSA Hub’s interests, expertise and commitment to specific areas of the study; (2) A scoping narrative literature review, utilizing the Arksey and O’Malley framework covering the time period corresponding to the initiation of funding (1999) of the original K30 Clinical Research Curriculum Awards through to the present CTSA funding period, incorporating Medical Subject Heading (MeSH) keywords (career development; career development plan; employee plan; mentoring plans; compacts; research contracts; career planning; mentor guide), initially delineated by USC reference librarian and to be expanded by reference librarian services from the Icahn School of Medicine at Mount Sinai and University of Rochester, and performed on NIH searchable databases including NCBI PubMed, Central and Medline & Worldwide Science; Web of Science, ProQuest, ProQuest Abi/Inform, Google Scholar, Cochrane, Ovid MEDLINE databases, as well as Google for published papers in English and Spanish. For this portion of the work, we will describe and characterize (1) research career development or progression constructs, domains, and milestones; (2) establish the presence or absence of defined and/or pre-specified timed milestone objectives and inclusion of SWOT analytics (strengths, weaknesses, opportunities, and threats) and/or Gantt chart approaches; (3) delineate IDPs structure, toolkits and their key features (competencies, skills acquisition and processes utilized); (4) and identify specific gaps to best address the need for personalized career development education. Based on this review, we will synthesize CTS milestones, develop a time frame for meeting RCD expectations, and establish RCD benchmarks for achieving these milestones, all in consensus with the IDP Collaborative Workgroup. RESULTS/ANTICIPATED RESULTS: Seventy-seven percent of the IDP CTSA’s responded to the online survey, led by University of Rochester, and the results can be summarized as follows: (1) 100% agreed that the IDP process is important and should be considerably improved to optimize effectiveness; (2) a range of diverse IDP formats are utilized, making comparisons across programs difficult; (3) 50% of CTSA hubs report only fair to good compliance with the IDP process; (4) a major barrier to the IDP process is lack of instruction regarding how best to utilize; (5) poor alignment of currently available IDPs designed for basic science PhDs with CTS investigators; (6) an absence of a CTS specific IDP to best foster RCD for this specific career trajectory. When asked: What are the barriers to writing a detailed and thoughtful IDP, responses in order of agreement from greatest to least were: No verification of acquired competencies, beyond self-report (56%), Static platform (38%), Not constructed for clinical and translational researcher (31%), No analytical or documentation on use (31%), No instruction given to scholars on how to use it effectively and efficiently (31%), The IDP we are using is more constructed for PhD students and postdoctoral fellows (25%), No instruction given to the scholars on why it is important as adult learners (19%), and Not constructed for early career physicians/scientist (13%). Additional progress has been made on our Scoping review: An initial ABI/Inform and PubMed USC research librarian conducted search using Author names yielded 72 articles, of which only 2 were relevant to the topic at hand. A ProQuest™ search yielded 19 potentially relevant articles, 11 of which were of relevance to the topic of IDPs; and a Google Scholar search yielded 18 and 25 on career development and self-management, respectively. This has enabled us to put forth an initial model of factors that impact the purpose and design of IDPs that includes? DISCUSSION/SIGNIFICANCE OF IMPACT: Discussion: Our initial data suggests that many CTSA institutions see the need to further enhance the mentoring process with a more informed and personalized IDP template and process. Furthermore, our initial scoping review suggests a framework upon which to build specific components of a more ideal and useful IDP to best guide mentored research career development of CTS trainees. Significance: Developing and evaluating collaborative evidence-based CTS IDP and corresponding e-Learning Guide could potentially prevent or reduce important delays in RCD, a common roadblock for the translation of clinical interventions. Ultimately, the CTS-IDP serves not only to support and frame a scholar’s RCD “habits of mind” during training and early career development but to also to achieve a sustainable long-term career at a CTS researcher equipped to meet the ever challenging and dynamic research landscape.
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47

Petrosian, Ovanes, and Victor Zakharov. "IDP-Core: Novel Cooperative Solution for Differential Games." Mathematics 8, no. 5 (May 4, 2020): 721. http://dx.doi.org/10.3390/math8050721.

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IDP-core is a new cooperative solution for dynamic and differential games. A novel approach of constructing solutions for dynamic and differential games was employed in which the time consistency property was used as the main axiom property for the cooperative solution. Another new and important approach used for constructing IDP-core is the IDP dominance, which allows to select undominated imputation distribution procedures and construct the cooperative solution or imputation set. This approach shows the potential of using the time consistency property as the main axiom for solutions in various fields such as Social Choice and Mechanism Design. The overall procedure for defining the cooperative solution is also new since IDP-core was constructed using imputation distribution procedures but not by using imputations directly.
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48

Mugo, Samuel M., Weihao Lu, and Scott V. Robertson. "Molecularly Imprinted Polymer-Modified Microneedle Sensor for the Detection of Imidacloprid Pesticides in Food Samples." Sensors 22, no. 21 (November 4, 2022): 8492. http://dx.doi.org/10.3390/s22218492.

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A portable, molecularly imprinted polymer (MIP)-based microneedle (MN) sensor for the electrochemical detection of imidacloprid (IDP) has been demonstrated. The MN sensor was fabricated via layer-by-layer (LbL) in-tube coating using a carbon nanotube (CNT)/cellulose nanocrystal (CNC) composite, and an IDP-imprinted polyaniline layer co-polymerized with imidazole-functionalized CNCs (PANI-co-CNC-Im) as the biomimetic receptor film. The sensor, termed MIP@CNT/CNC MN, was analyzed using both cyclic voltammetry (CV) and differential pulse voltammetry (DPV) and showed excellent electrochemical performance for the detection of IDP. The CV detection range for IDP was 2.0–99 µM, with limits of detection (LOD) of 0.35 µM, while the DPV detection range was 0.20–92 µM with an LOD of 0.06 µM. Additionally, the MIP@CNT/CNC MN sensor showed excellent reusability and could be used up to nine times with a 1.4 % relative standard deviation (% RSD) between uses. Lastly, the MIP@CNT/CNC MN sensor successfully demonstrated the quantification of IDP in a honey sample.
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49

Chang, Chi-Ning, Clinton A. Patterson, Nathan L. Vanderford, and Teresa M. Evans. "Modeling individual development plans, mentoring support, and career preparedness relationships among Doctor of Philosophy (Ph.D.) trainees in the life sciences." F1000Research 10 (December 17, 2021): 626. http://dx.doi.org/10.12688/f1000research.53705.2.

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Background: As greater career development support for doctoral students and postdoctoral researchers has been emphasized, the individual development plan (IDP) has become a recommended mentoring tool. However, little is known about the effect of IDPs on mentoring and career development. This study proposed two conceptual models to examine the interrelationships among the use of IDPs, mentoring support, and career preparedness with a diverse sample of doctoral students and postdoctoral researchers in the life sciences. Methods: The data leveraged for this study was collected over a three-month period, March 2016 to June 2016, as part of a cross-sectional, online survey. The survey was distributed through social media and direct email to participants enrolled in life/biological/medical or physical/applied doctoral programs at U.S. institutions. To test the proposed conceptual models, this study employed the design-based multilevel structural equation modeling. Results: The analytic sample comprised 660 doctoral students and postdoctoral researchers in the life sciences from 91 institutions. The results suggested that 1) using the IDP could enhance mentoring support and career preparedness of doctoral students and postdoctoral researchers; 2) greater mentoring support and career preparedness would motivate mentees to continue utilizing the IDP with their principal investigator (PI) or advisor; and 3) females, postdoctoral researchers, and international scholars might need more support throughout the mentoring and career development process. Conclusions: This research offered empirical evidence for how an IDP, mentorship, and career preparedness interact. Findings revealed the IDP enhances mentoring support and career preparedness, as well as mentoring support and career preparedness predict IDP use. We conclude the IDP is an important mentorship tool that enhances trainees’ overall career preparation.
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50

Fagen, P. W. "Peace Processes and IDP Solutions." Refugee Survey Quarterly 28, no. 1 (January 1, 2009): 31–58. http://dx.doi.org/10.1093/rsq/hdp004.

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