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1

Looser, Jens. Identification of two novel CVC domain-containing homeobox genes. Ottawa: National Library of Canada, 1995.

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2

Vanti, William B. Identification of a null mutation in a trace amine receptor gene and nine novel G-protein-coupled receptor genes. Ottawa: National Library of Canada, 2003.

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3

Tomlekova, N. B., M. I. Kozgar, and M. R. Wani, eds. Mutagenesis: exploring novel genes and pathways. The Netherlands: Wageningen Academic Publishers, 2014. http://dx.doi.org/10.3920/978-90-8686-787-5.

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4

To, Minh Dong. Identification of transcriptionally deregulated genes in breast cancer. Ottawa: National Library of Canada, 1998.

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5

King, Kathryn Elizabeth. Identification and analysis of genes expressed during chondrocyte differentiation. Manchester: University of Manchester, 1997.

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6

Finelli, Antonio. Identification of genes important to Pseudomonas aeruginosa biofilm formation. Ottawa: National Library of Canada, 2001.

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7

Buchanan, Edna. Legally dead: A novel. New York: Simon & Schuster, 2008.

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8

Lee, Dennis K. Characterization of novel G protein-coupled receptor genes and the novel ligand apelin. Ottawa: National Library of Canada, 1999.

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9

Philbin, Tom. Blink: A novel. New York: Jove Books, 1994.

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10

Philbin, Tom. Blink: A novel. New York: Jove Books, 1994.

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11

Kagan, Elaine. Somebody's baby: A novel. New York: Wm. Morrow and Co., 1998.

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12

Bail, Murray. Eucalyptus: A novel. New York: Picador, 2007.

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13

Father found: A novel. New York: Washington Square Press, 2001.

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14

Sprowl, Jason A. Identification of PKCa-dependent genes associated with growth arrest in Saccharomyces cerevisiae. Sudbury, Ont: Laurentian University, 2004.

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15

Blood kin: A novel. New York: Morrow, 1992.

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16

Perry, Claire Louise. A search for novel MHC-encoded IDDM susceptibility genes using oriental haplotypes. Birmingham: University of Birmingham, 1997.

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17

See, Lisa. Dreams of joy: A novel. New York: Random House, 2011.

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18

Association, UBC Academic Women's, ed. Schools of sympathy: Gender and identification through the novel. Montreal: McGill-Queen's University Press, 1997.

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19

Michael, Ian. Epic to romance to novel: Problems of genre identification. Manchester: John RylandsUniversity Library of Manchester, 1986.

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20

Nancy, Roberts. Schools of sympathy: Gender and identification through the novel. [Vancouver]: University of British Columbia, Academic Women's Association, 1997.

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21

Lorenzen, Angela. Identification and characterization of Ah receptor in novel specimens. Ottawa: National Library of Canada, 1990.

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22

Hingley-Wilson, Suzanne Maria. The detection and identification of macrophage genes induced by intracellular infection with mycobacterium tuberculosis. Birmingham: University of Birmingham, 1998.

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23

Hagens, Olivier. An investigation of two novel genes associated with Wnt signalling in Drosophila melanogaster. Brighton, UK: University of Sussex, 2000.

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24

Sawzdargo, Marek. Discovery of novel G protein-coupled receptor genes including human GALR3 receptor gene. Ottawa: National Library of Canada, 1999.

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25

Lutman, Mark E. Novel methods for early identification of noise-induced hearing loss. Sudbury: HSE Books, 2000.

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26

Barnes, Ruth C. Identification and characterisation of a novel human serpin gene: Leupin. Dublin: University College Dublin, 1998.

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27

Eucalyptus: A novel. San Diego: Harcourt Brace, 1999.

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28

Bail, Murray. Eucalyptus: A novel. London: Harvill Press, 1998.

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29

Eucalyptus: A novel. New York: Farrar, Straus, and Giroux, 1998.

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30

El-Aggoury, Abdelgader K. Youssef. Identification of genes that are differently expressed with retinoic acid treatment in early Xenopus embryos. [s.l.]: typescript, 1997.

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31

Whittaker, Catherine Jill. Identification and cloning of Streptococcus gordonii LGR2 genes encoding adhesins for saliva-coated hydroxyapatite (SHA). Manchester: University of Manchester, 1993.

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32

Docherty, John Martin. The cloning and characterization of three novel human genes encoding G protein-coupled receptors. Ottawa: National Library of Canada, 1994.

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33

Barondes, Samuel H. Mood genes: Hunting for origins of mania and depression. London: Penguin, 1999.

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34

Bowman, John Alfred Leng. Identification and characterization of a novel RNA-binding domain in SRM160. Ottawa: National Library of Canada, 2001.

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35

Foussias, George. Identification, characterization, and mapping of novel members of the siglec family. Ottawa: National Library of Canada, 2001.

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36

Chang, Albert. Identification and characterization of a novel kallikrein gene Klk-L4/KLK13. Ottawa: National Library of Canada, 2001.

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37

Subarnas, Anas. Identification of novel anticancer compounds from primates-consumed plant: Final report. Jakarta]: Kementerian Pendidikan Nasional, 2010.

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38

Subarnas, Anas. Identification of novel anticancer compounds from primates-consumed plant: Final report. Jakarta]: Kementerian Pendidikan Nasional, 2010.

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39

Cao, Chenglong. Immunological screening of a rat brain cDNA library for genes encoding potential novel glutamate receptors. Ottawa: National Library of Canada, 1993.

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40

Oleksiak, Marjorie Frances. Diversity and characterization of novel Cytochrome P450 2 genes in the marine teleost Fundulus Heteroclitus. Woods Hole, Mass: Massachusetts Institute of Technology, Woods Hole Oceanographic Institution, Joint Program in Oceanography/Applied Ocean Science and Engineering, 1998.

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41

The V.I.P.s: A novel. New York: Broadway Books, 2011.

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42

Hardy, Robin. The wicker man: A novel. London: Pan, 2000.

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43

Cerullo, Dante. Identification of a novel diagnostic marker for viral myocarditis using cDNA microarrays. Ottawa: National Library of Canada, 2003.

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44

Keyes, Feenagh Anne. An approach to the identification of novel eukaryotic transcription intermediary factorsfrom S.cerevisiae. Manchester: University of Manchester, 1995.

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45

Mood genes: Hunting for origins of mania and depression. New York: W.H. Freeman, 1998.

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46

The Peculiars: A novel. New York: Amulet Books, 2012.

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47

Obinwa, Ngozika Kanayo. Identification and cloning of Streptococcus gordonii LGR2 and Streptococcus crista CR311 genes encoding their coaggregations with other oral bacteria. Manchester: University of Manchester, 1996.

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48

Feio, Maria José Faria. Characterisation and identification of two novel species of sulphate-reducing bacteria from marine environments. Portsmouth: University of Portsmouth, 2000.

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49

Chang, Michael. Identification of novel DNA damage response genes using functional genomics. 2005.

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50

Pezzini, Alessandro. Genetics. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198722366.003.0011.

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Ischaemic stroke is a heterogeneous multifactorial disorder. Although epidemiological data from twin and family studies provide substantial evidence for a genetic basis for stroke, the contribution of genetic factors identified so far is small. Large progress has been made in single-gene disorders associated with ischaemic stroke, particularly at young age. By contrast, little is known about the genes associated with multifactorial stroke. The reported genome-wide association studies of ischaemic stroke have shown that no single common genetic variant imparts major risk, but data on early-onset disease are scarce in this regard. Larger studies with samples numbering in the thousands are ongoing to identify common variants with smaller effects on risk. This approach, in addition with new analytic techniques, will likely contribute to the identification of additional genes, novel pathways, and eventually novel therapeutic approaches to cerebrovascular disorders in the near future. The aims of this review are to summarize data on clinical, genetic, and epidemiologic aspects of monogenic conditions associated with juvenile ischaemic stroke, to discuss recent findings and methodological limitations regarding the genetics of sporadic ischaemic stroke in this age category, and to provide a brief overview of the potential future approaches to stroke genetics.
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