Academic literature on the topic 'IB12'
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Journal articles on the topic "IB12"
Panigrahy, Rabi Narayan, Susanta Kumar Panda, and Prabhakar Reddy Veerareddy. "FORMULATION AND IN VITRO EVALUATION OF COMBINED FLOATING-BIOADHESIVE TABLETS OF IMATINIB MESYLATE." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (November 1, 2017): 27. http://dx.doi.org/10.22159/ijpps.2017v9i11.18894.
Full textLitaiff, Eleilza de Castro, Wanderli Pedro Tadei, Jorge Ivan Rebelo Porto, and Ila Maria de Aguiar Oliveira. "Analysis of toxicity on Bacillus sphaericus from amazonian soils to Anopheles darlingi and Culex quinquefasciatus larvae." Acta Amazonica 38, no. 2 (2008): 255–62. http://dx.doi.org/10.1590/s0044-59672008000200008.
Full textGrisaru, Dan A., Allan Covens, Edmee Franssen, William Chapman, Patricia Shaw, Terence Colgan, Joan Murphy, et al. "Histopathologic score predicts recurrence free survival after radical surgery in patients with stage IA2–IB12 cervical carcinoma." Cancer 97, no. 8 (April 15, 2003): 1904–8. http://dx.doi.org/10.1002/cncr.11269.
Full textPark, Nae Yoon, Gun Oh Chong, Dae Gy Hong, Young Lae Cho, Il Soo Park, and Yoon Soon Lee. "Oncologic Results and Surgical Morbidity of Laparoscopic Nerve-Sparing Radical Hysterectomy in the Treatment of FIGO Stage IB Cervical Cancer: Long-Term Follow-Up." International Journal of Gynecologic Cancer 21, no. 2 (January 2011): 355–62. http://dx.doi.org/10.1097/igc.0b013e31820731bb.
Full textSegaert, An, Koen Traen, Philippe Van Trappen, Frederik Peeters, Karin Leunen, Frédéric Goffin, and Ignace Vergote. "Robot-Assisted Radical Hysterectomy in Cervical Carcinoma: The Belgian Experience." International Journal of Gynecologic Cancer 25, no. 9 (November 2015): 1690–96. http://dx.doi.org/10.1097/igc.0000000000000536.
Full textWydra, D., S. Sawicki, S. Wojtylak, T. Bandurski, and J. Emerich. "Sentinel node identification in cervical cancer patients undergoing transperitoneal radical hysterectomy: a study of 100 cases." International Journal of Gynecologic Cancer 16, no. 2 (March 2006): 649–54. http://dx.doi.org/10.1136/ijgc-00009577-200603000-00030.
Full textMubarak, Fhahri, Wahyu Hendrarti, Hamdayani Lance Abidin, and Arfan Abu Bakar. "Identification of Antibiotic-Producing Isolates from the Soil of Pesantren Darul Aman Gombara, Makassar." Indonesian Journal of Pharmaceutical Science and Technology 9, no. 3 (December 29, 2022): 181. http://dx.doi.org/10.24198/ijpst.v9i3.32257.
Full textSchoorlemmer, Jon, and Mitchell Goldfarb. "Fibroblast Growth Factor Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-activated Protein Kinase." Journal of Biological Chemistry 277, no. 51 (September 18, 2002): 49111–19. http://dx.doi.org/10.1074/jbc.m205520200.
Full textSandadi, Samith, Edward J. Tanner, Fady Khoury-Collado, Alessandra Kostolias, Vicky Makker, Dennis S. Chi, Yukio Sonoda, Kaled M. Alektiar, Richard R. Barakat, and Nadeem R. Abu-Rustum. "Radical Surgery With Individualized Postoperative Radiation for Stage IB Cervical Cancer: Oncologic Outcomes and Severe Complications." International Journal of Gynecologic Cancer 23, no. 3 (March 2013): 553–58. http://dx.doi.org/10.1097/igc.0b013e3182849d53.
Full textLea, Jayanthi Sivasothy, Steven Holloway, Wenxin Zheng, Hao Chen, and Glorimar Rivera. "Significance of degree of destructive stromal invasion in early stage endocervical adenocarcinoma." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e17023-e17023. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e17023.
Full textDissertations / Theses on the topic "IB12"
Jennings, Jason Samuel Robert. "Candidate inflammatory bowel disease gene analysis at the IBD2 locus." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445947.
Full textMoore, Joel M. "Investigating the DNA binding properties of the initiator binding protein 2 (IBP2) in maize (Zea mays)." Tallahassee, Florida : Florida State University, 2009. http://etd.lib.fsu.edu/theses/available/etd-11092009-115855/.
Full textAdvisor: Hank W. Bass, Florida State University, College of Arts and Sciences, Dept. of Biological Science. Title and description from dissertation home page (viewed on May 3, 2010). Document formatted into pages; contains vi, 23 pages. Includes bibliographical references.
Moes, Michèle. "Interaction of the cytoskeletal protein talin with the integrin beta3 subunit cytoplasmic tail: characterization of the talin rod IBS2 integrin binding site." Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210658.
Full textIn the first part of this study, we used a combination of three different experimental approaches to define the minimal structure of talin IBS2: 1) an in silico bioinformatics approach to analyse sequence conservation of talin IBS2, 2) an in vivo cell biology approach to study the subcellular localization of recombinant talin fragments covering IBS2 in CHOáIIbâ3 cells, and 3) an in vitro biochemical approach consisting in protein overlay, pull down and Surface Plasmon Resonance (SPR) assays, to study the direct interaction between talin IBS2 and the integrin â3 subunit. We delineated IBS2 to a single amphipathic á-helical repeat of 23 residues within the talin rod domain. We further provided evidence that a two amino acid mutation(L2094I2095/AA) was sufficient to inactivate the IBS2 site, due to a disruption of the á helix structure, as demonstrated by infrared spectroscopy. In addition, we identified 2 lysine residues (K2085, K2089) exposed on the solvent face of á helix 50, which are directly involved in the talin IBS2-integrin interaction.
In the second part of this study, we investigated the functional role of talin IBS2 in spreading defective talin (-/-) cells and showed that in contrast to full-length wild type talin, an IBS2 LI/AA mutant talin was unable to fully rescue the spread phenotype of these cells. These results provide the first direct evidence that IBS2 in the talin rod is essential to link integrins to the actin cytoskeleton.
Doctorat en Sciences
info:eu-repo/semantics/nonPublished
Alleyne-Mike, Kellie. "A retrospective study of patients with Stage IB2 cervical cancer treated at Groote Schuur Hospital 1993-2008." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/2854.
Full textGroßmann, Mona [Verfasser], S. [Akademischer Betreuer] Zierz, G. [Akademischer Betreuer] Stoltenburg-Didinger, and R. [Akademischer Betreuer] Horstkorte. "Die C57BL/6 GNE+/-Maus als Modell für die hereditäre Einschlusskörpermyopathie Typ 2 (h-IBM2) / Mona Großmann. Betreuer: S. Zierz ; G. Stoltenburg-Didinger ; R. Horstkorte." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2016. http://d-nb.info/1089085214/34.
Full textTucher, von Simmelsdorf Elisabeth Maria [Verfasser]. "Therapieoptionen bei der Behandlung des invasiven Zervixkarzinoms FIGO IA1 L1- IB1 bei Patientinnen im fertilen Alter / Elisabeth Freifrau Tucher von Simmelsdorf." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1029848718/34.
Full textNascimento-Fonseca, Sandra Marques. "Outcomes of patients with stage IB1 and IB2 Cervical Cancer who have had Wertheim's Hysterectomies with or without adjuvant chemo-radiotherapy as primary treatment at Charlotte Maxeke Johannesburg Academic Hospital." Thesis, 2018. https://hdl.handle.net/10539/25267.
Full textBackground Cervical cancer is the 3rd most common female malignancy worldwide. It is classified and managed according to stage as defined by the FIGO Committee on Gynaecology Oncology classification of 2009. Stage specific treatment is tailored according to prognosis and risk of recurrence as determined by tumour type, tumour size, tumour grade, lymph node metastases, lymphovascular space involvement (LVSI), parametrial spread and presence of any other metastatic deposits at presentation. This study only concentrated on patients who presented with Stage IB1 and 1B2 tumours managed by Class III / Meig’s Radical / Wertheim’s hysterectomy and bilateral pelvic lymphadenectomy. Aims Primary Outcome 1. Assess disease free interval and overall survival 2 years post-operatively. Secondary Outcomes 1. Assess adequacy of patient selection 2. Assess risk factors for recurrence 3. Compare recurrence risk of HIV positive patients versus HIV negative patients. 4. Determine surgical and post-surgical complication rate. Materials and Methods This was a retrospective institutional cohort study conducted at the Charlotte Maxeke Johannesburg Academic Hospital. All patients with Stage IB1 or IB2 cervical cancer treated with Wertheim hysterectomies between 2002 and 2012 were included. Surgical records, histology records, further postoperative management records and gynaecological outpatient follow up records were used to collect data for the patients. Histological findings post-operatively determined further management. Surgical margins had to be 10mm clear of tumour with no positive lymph nodes otherwise external beam radiotherapy and brachytherapy or chemo-radiotherapy were recommended in addition to primary surgical management. Results Of the 72 patients initially identified, 69 patients were suitable for study inclusion. The mean age of the study population was 45 years. Study population racial distribution: 68.12% were Black, 26.09% were White, 2.9% were Coloured and 2.9% were Indian. Average parity and gravidity of patients alive at the end of the study was 2.86 and 3.56; while average parity and gravidity of patients deceased at the end of the study was 2.5 and 2.8 respectively. Study population ECOG status: 16% were ECOG 0, 83% were ECOG 1 and 1% were ECOG 2. Overall survival at the end of the study was 86% and patients were disease free postoperatively for an average of 5 years. Thirty three percent of the patients were disease free for more than 5 years. Preoperative clinical staging and postoperative histological staging correlated only in 61% of cases. Correct management by Wertheim’s hysterectomy was rendered to 75% of patients whereas the remainder were incorrectly managed and should have had either a simple hysterectomy with no pelvic lymphadenectomy or radiotherapy only as primary therapy. More advanced stages, tumours ≥ 4cm, adenomatous cell type, > 5mm depth of invasion, >7mm lateral spread, higher number of nodes positive for metastatic disease, surgical margins 10mm, positive lympohovascular space, parametrial and pouch of Douglas (POD) involvement were factors that had a poorer prognosis with regards overall survival, disease-free interval or both. Poorly differentiated tumours were more likely to recur but did not have a poorer prognosis compared with regards to overall survival or disease free interval at 2 or more years compared to well and moderately differentiated tumours. Mortality of HIV reactive patients was 16.7% compared to 12.5% for HIV non-reactive patients. This difference was not statistically significant at the 95% confidence level. HIV status also did not increase risk of recurrence. Lower CD4 counts were shown to have a lower disease-free period and overall survival. Intra-operative surgical complication rate was 6%. Immediate post-operative complication rate was 16%. Of the patients who required DXT or DXT and chemotherapy 33% had side-effects or complications from adjuvant therapy. Patients treated with DXT and chemotherapy had had more side-effects than those treated with DXT only. Conclusion The mean age of the study population was 45 years. This was lower compared to other larger studies possibly due to younger presentation related to HIV disease. HIV positive patients with lower CD4 counts were shown to have poorer prognosis with regards to survival. HIV status was not shown to be a risk factor for recurrence. The overall survival and disease-free period at 5 years was similar to that of other international studies. Only two thirds of the patients were adequately selected for surgery according to the institution’s criteria for a Wertheim’s hysterectomy and therefore it may be necessary to reconsider the pre-operative assessment of these patients. More advanced stages, tumours ≥ 4cm, adenomatous cell type, poor differentiation, > 5mm depth of invasion, >7mm lateral spread, higher number of nodes positive for metastatic disease, surgical margins ≤ 10mm, positive lympohovascular space, parametrial and pouch of Douglas involvement were factors that had a poorer prognosis with regards to recurrence, overall survival and disease-free interval. However, the rates of recurrence were not statistically significant at a 95% confidence level.
LG2018
Lin, Hsien-Ai, and 林仙艾. "Treatments for stage IB2 of cervical cancer –A study at medical center in central area of Taiwan." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/s3ubp5.
Full text東海大學
工業工程與經營資訊學系
103
Cervical cancer is the third leading cause of female cancer worldwide. It is estimated to be responsible for 530,000 new cases of cancer in 2008 (nearly one in ten (9%) of all cancers diagnosed in women). From the FIGO annual repot the average 5 year survival rate drop dramatically from 90% to 75% for stage IB1 and IB2, respectively. The treatment policy for stage IB2 is more controversial than other stages and including concomitant chemoradiation, primary radical hysterectomy with retroperitoneal lymph dissection, and concomitant chemoradiation followed by hysterectomy. Each method has their benefits and shortcomings. In treatment stage IB2 cervical cancer, neoadjuvant chemotherapy followed by radical hysterectomy will improve survival compare to operation alone. Intensity modulated radiotherapy (IMRT) and concomitant chemotherapy was found to have good efficacy at the same time favorable acute and late toxicities. Now that these two treatment strategies both offer benefits to stage IB2 cervical cancer patients, which one should be the first choice, including: radical hysterectomy, neoadjuvant chemotherapy followed by radical hysterectomy, radiotherapy, or concomitant chemoradiation therapy should be determined by clinical trials. However, from Pubmed search, there were only few studies involving the comparison of these four methods of treatment. Therefore , we hope that through this retrospective study to explore ways for the treatment of cervical cancer IB2.
洪懿慈. "Discovery of Novel RAD 51 and NF-kB Inhibitors : IBR2 Analogues and Aminofuran fused Benzimidazole and Synthesis of Phosphonyl Pyrazole fused Benzimidazole." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/9dfyeg.
Full text國立交通大學
應用化學系碩博士班
100
In this thesis, we used multicomponent reactions for synthesis of different main architecture of small organic molecules and did the biological screening for anticancer activity, in order to identify the high inhibition of drug leads. This thesis can be divided into three parts: The first part reported the improvement of the synthetic approach for the assembling of IBR2 analogues. The original two steps synthetic route was improved to one pot tandem reaction and the reaction time was reduced to 30 minutes from 20 hours. Based on this efficient synthetic approach, a series of IBR2 derivatives were prepared and these IBR2 analogues were subjected to biological screening. The second part informed that the used of 2-cyanomethylbenzimidazole and 2-bromoacetophenone for cyclization reaction to synthesis the molecular library which conformation has the furan structure as well as studied the structure-activity relationship. The third part used 2-cyanomethylbenzimidazole as a starting material through condensation reaction and cyclization reaction with aldehyde and Bestmann-Ohira reagent for synthesis the molecular library which conformation has the pyrazole structure.
Books on the topic "IB12"
Learning to Use Office 2000 (Clait Ibt2). Heinemann Educational Publishers, 2000.
Find full textKemeny, John G., and Thomas E. Kurtz. True Basic: The Structured Language System for the Future (07-Ibm2/L, Version 2.1). 2nd ed. True Basic, 1987.
Find full textBook chapters on the topic "IB12"
Wang, H. Hau, and Jack M. Williams. "Ambient-Pressure Superconducting Synthetic Metals β-(Bedt-TTF)2 X, X = I3 - , IBr2 - , and AuI2 -." In Inorganic Syntheses, 41–50. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132609.ch14.
Full textDachir, Shlomit, Izhak Barness, Eliezer Fishbine, Jacob Meshulam, Rita Sahar, Arik Eisenkraft, Adina Amir, and Tamar Kadar. "Dermostyx (IB1): High Efficacy and Safe Topical Skin Protectant Against Percutaneous Toxic Agents." In Skin Decontamination, 183–98. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-24009-7_11.
Full textSong, Chaohong. "Prediction of Bacterial Toxins by Feature Representation of Position Specific Scoring Matrix and IB1 Classifier Fusion." In Communications in Computer and Information Science, 645–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19853-3_95.
Full textWhangbo, Myung-Hwan, Jack M. Williams, Arthur J. Schultz, and Mark A. Beno. "Importance of Intermolecular Hydrogen — Hydrogen and Hydrogen — Anion Contacts for the Lattice Softness and the Superconductivity of β-(ET)2X (X− = I3−, AuI2−, IBr2−." In Organic and Inorganic Low-Dimensional Crystalline Materials, 333–36. New York, NY: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4899-2091-1_29.
Full text"Repair of bridge IB42 over the Limpopo river at Stockpoort border post." In Concrete Repair, Rehabilitation and Retrofitting II, 297–98. CRC Press, 2008. http://dx.doi.org/10.1201/9781439828403-113.
Full textHumphries, W., and E. Kruger. "Repair of bridge IB42 over the Limpopo river at Stockpoort border post." In Concrete Repair, Rehabilitation and Retrofitting II, 279–80. CRC Press, 2008. http://dx.doi.org/10.1201/9781439828403.ch101.
Full textVEITH, H., F. GROSS, C. P. HEIDMANN, K. ANDRES, H. FUCHS, and E. AMBERGER. "MEISSNER EFFECT UNDER PRESSURE IN ORGANIC SUPERCONDUCTORS OF THE β-(BEDT-TTF)2X FAMILY (X = I3, IBr2, AuI2)." In Proceedings of the Yamada Conference XV on Physics and Chemistry of Quasi One-Dimensional Conductors, 360–62. Elsevier, 1986. http://dx.doi.org/10.1016/b978-1-4832-2812-9.50107-5.
Full textMarchocki, Zibi, and Allan Covens. "Is Radical Surgery or Parametrectomy Needed for Early-stage FIGO IA2 and Microscopic IB1 Cervical Cancer?" In 50 Big Debates in Gynecologic Oncology, 262–64. Cambridge University Press, 2023. http://dx.doi.org/10.1017/9781108935579.086.
Full textNam, Joo-Hyun, and Jeong-Yeol Park. "Is Radical Surgery or Parametrectomy Needed for Early-stage FIGO IA2 and Microscopic IB1 Cervical Cancer?" In 50 Big Debates in Gynecologic Oncology, 259–61. Cambridge University Press, 2023. http://dx.doi.org/10.1017/9781108935579.085.
Full textPlante, Marie. "What is the Best Management Option for Young Women with Stage IB2 Cervical Cancer Who Wish to Preserve Fertility?" In 50 Big Debates in Gynecologic Oncology, 268–71. Cambridge University Press, 2023. http://dx.doi.org/10.1017/9781108935579.088.
Full textConference papers on the topic "IB12"
Meschini, Tommaso, Valeria Artuso, Gabriella Schivardi, Luigi Antonio De Vitis, Francesco Multinu, Nerea Martin-Calvo, Luis Chiva, Fabio Ghezzi, and Jvan Casarin. "#466 Adjuvant radiation therapy for surgically staged FIGO 2018 IB1-IB2 cervical cancer: is it time for a change?" In ESGO 2023 Congress. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/ijgc-2023-esgo.146.
Full textLim, Hyunji, Se Ik Kim, Hee Seung Kim, Hyun Hoon Chung, Jae-Weon Kim, Noh Hyun Park, Yong-Sang Song, Chel Hun Choi, and Maria Lee. "EP075/#714 Survival outcomes from laparoscopic radical hysterectomy without preoperative cervical conization in 2018 FIGO stage IB1-IB2 cervical cancer." In IGCS 2022 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-igcs.166.
Full textH., Oswin Rahadiyan, Gloria Virginia, and Antonius Rachmat C. "Sentiment Classification of Film Reviews Using IB1." In 2016 7th International Conference on Intelligent Systems, Modelling and Simulation (ISMS). IEEE, 2016. http://dx.doi.org/10.1109/isms.2016.38.
Full textHurtado Estrada, G. "180 Modified radical hysterectomy for cervical cancer IB1." In IGCS Annual 2019 Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-igcs.180.
Full textFerguson, Peter J., Morgan Black, Rene Figueredo, Mark D. Vincent, and James Koropatnick. "Abstract 3057: Synergistic antiproliferative activity between anticancer drugs and RAD51 inhibitors IBR2 and IBR120." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3057.
Full textFerguson, Peter J., Morgan Black, Rene Figueredo, Mark D. Vincent, and James Koropatnick. "Abstract 3057: Synergistic antiproliferative activity between anticancer drugs and RAD51 inhibitors IBR2 and IBR120." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3057.
Full textVranes, B. "P45 Pathology review of stage IA2 microinvasive and small diameter stage IB1 cervical cancer." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.107.
Full textPanchbhaya, N., E. Marchand, C. Mimoun, AS Leveau Vallier, V. Place, and M. Mezzadri. "EP377 Total laparoscopic radical trachelectomy with uterine arteries preservation for stage IB2 cervical cancer." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.436.
Full textKim, Sang Il, and Jisu Yun. "Robot-assisted versus conventional laparoscopic radical hysterectomy in cervical cancer stage IB1 (FIGO 2018)." In KSGO 2023. Korea: Korean Society of Gynecologic Oncology, 2023. http://dx.doi.org/10.3802/jgo.2023.34.s1.c03.
Full textMandic, A., M. Davidovic Grigoraki, B. Gutić, N. Prvulović Bunović, and N. Šolajić. "EP353 Fertility sparing surgery following neoadjuvant chemotherapy of cervical cancer figo stage IB2 – case report." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.412.
Full textReports on the topic "IB12"
Cheng, Jing, BeiBei Liu, Lin Xu, Biao Wang, XC Long, ZH Li, and RT Wu. Effectiveness comparisons of various therapies for FIGO stage IB2/IIA2 cervical cancer: a Bayesian network meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2020. http://dx.doi.org/10.37766/inplasy2020.10.0069.
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