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1

Frykman, Erik, Catherine Sandbach-Dahlström, Sybil Oldfield, Nicholas Shakespeare, Marianne Levander, Rolf Lundén, Lars-Olof Nyhlén, et al. "Reviews and notices." Moderna Språk 85, no. 2 (December 1, 1991): 196–223. http://dx.doi.org/10.58221/mosp.v85i2.10339.

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Includes the following reviews: pp. 196-197. Erik Frykman. Eccles, C., The Rose Theatre. pp. 197-198. Catherine Sandbach-Dahlström. Blain, V., Clements, P. & Grundy, I. (eds.), The Feminist Companion to Literature in English. pp. 198-199. Sybil Oldfield. Pritchard, R.E., Poetry by English Women, Elizabethan to Victorian. + Zahava, I., My Father's Daughter - Stories by a Woman. pp. 199-200. Sybil Oldfield. Åhmansson, G., A Life and Its Mirrors: A Feminist Reading of L.M. Montgomery's Fiction. Vol. 1. pp. 200-201. Nicholas Shakespeare. Schirmer, G.A., William Trevor: A Study of His Fiction. pp. 201-202. Marianne Levander. Imhof, R. (ed.), Contemporary Irish Novelists. pp. 202-203. Rolf Lundén. Franklin V, B. (ed.), Geer, G. & Haig, J., Dictionary of American Literary Characters. pp. 204-205. Lars-Olof Nyhlén. Homberger, D., Sachwörterbuch zur deutschen Sprache und Grammatik. pp. 206-208. Magnus Nordén & Klaus Rossenbeck. Schottmann, H. & Petersson, R., Wörterbuch der schwedischen Phraseologie in Sachgruppen. pp. 209-211. Gustav Korlén. Lehnert, M., Anglo-Americanisches im Sprachgebrauch der DDR. + Dieter Schlosser, H., Die deutsche Sprache in der DDR zwischen Stalinismus und Demokratie. Historische, politische und kommunikative Bedingungen. pp. 212-213. Uta Schuch. Palm, C., "Wir graben den Schacht von Babel" oder Kafkas "Urteil". Versuch einer semasiologisch-textlinguistischen Analyse. pp. 214-215. Johann Holzner. Sternberg, C., Ein treuer Ketzer. Studien zu Manès Sperbers Romantrilogie "Wir eine Träne im Ozean". pp. 216-218. Göran Bornäs. Actes du colloque franco-danois de lexicographie. pp. 218-220. Göran Fäldt. Cabanis, J., Mauriac, le roman et Dieu. pp. 220-222. Mats Forsgren. Eriksson, O. & Tegelberg, E., Svensk-franska strukturövningar med facit. p. 223. A Message from the Editors.
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2

Karim, MR, MM Rahman, and AKM Quamruzzaman. "Genetic divergence in eggplant (Solanum melongena L.) genotypes." Bangladesh Journal of Agricultural Research 41, no. 3 (September 24, 2016): 433–39. http://dx.doi.org/10.3329/bjar.v41i3.29715.

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Multivariate analysis of twenty six genotypes of eggplant were done to estimate the genetic diversity and to select the potential parents for a successful hybridization program. As per PCA, D2 and cluster analysis, the genotypes were grouped into five clusters. The highest inter-cluster distance was between Cluster II and Cluster III (37.82) and the lowest between Cluster I and Cluster III (4.39). Cluster III showed the maximum intra-cluster distance (1.58), whereas Cluster II showed the lowest intra-cluster distance (0.48). Considering the magnitude of genetic distance and agronomic performance, the genotypes SM 208 and SM 209 from Cluster II and SM 201, SM 218 and SM 227 from Cluster III might be suitable for efficient hybridization program. On the other hand the genotypes of Cluster I (SM 206, SM 210, SM 211, SM 212, SM 213, SM 215, SM 216, SM 217, SM 221, SM 224, SM 225 and SM 226) possess all the superior characters in respect of yield and yield related component. Thus the genotypes SM 206, SM 216, SM 217, SM 224 and SM 225 from this Cluster could be selected to develop high yielding eggplant varieties.Bangladesh J. Agril. Res. 41(3): 433-439, September 2016
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3

Deckhut, A. M., and S. S. Tevethia. "Effect of point mutations in the native simian virus 40 tumor antigen, and in synthetic peptides corresponding to the H-2Db-restricted epitopes, on antigen presentation and recognition by cytotoxic T lymphocyte clones." Journal of Immunology 148, no. 10 (May 15, 1992): 3012–20. http://dx.doi.org/10.4049/jimmunol.148.10.3012.

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Abstract The effects on CTL recognition of individual amino acid substitutions within epitopes I, II, and III of SV40 tumor Ag (T Ag) were examined. Epitope I spans amino acids 207 to 215, and epitope II/III is within residues 223 to 231 of SV40 T Ag. An amino acid substitution at position 207 (Ala----Val) or 214 (Lys----Glu) of SV40 T Ag expressed in transformed cells resulted in loss of epitope I, recognized by CTL clone Y-1. The amino acid substitution at residue 214 in the corresponding synthetic peptide, LT207-215(214-Lys----Glu), also led to loss of recognition by CTL clone Y-1. The recognition, by CTL clone Y-1, of peptides LT207-215 and LT207-217 with an Ala----Val substitution at position 207 was severely affected. Peptides LT205-215 and LT205-219 with the Ala----Val substitution at residue 207 were, however, recognized by CTL clone Y-1, suggesting that residues 205 and 206 may be involved in presentation of site I. Alteration of residue 224 (Lys----Glu) in the native T Ag resulted in loss of recognition by both CTL clones Y-2 and Y-3. However, a peptide corresponding to epitope II/III with an identical amino acid substitution at residue 224 provided a target for CTL clone Y-3 but not clone Y-2. A change of Lys----Gln at residue 224 in both the native protein and a synthetic peptide caused loss of recognition by CTL clone Y-2 but not CTL clone Y-3. Further, an amino acid substitution of Lys----Arg at position 224 of the native T Ag decreased recognition of epitope II/III by CTL clones Y-2 and Y-3 but had no effect on recognition of a synthetic peptide bearing the same substitution. These results indicate that the mutagenesis approach, resulting in identical amino acid substitutions in the native protein and in the synthetic peptides, may provide insight into the role of individual residues in the processing, presentation, and recognition of CTL recognition epitopes.
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4

Roda, Jean-Marc. "Form function for the `I-214' poplar merchantable stem (Populus � euramericana (Dode) Guinier cv cultivar `I-214')." Annals of Forest Science 58, no. 1 (January 2001): 77–87. http://dx.doi.org/10.1051/forest:2001108.

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5

VERONESI, Vanni. "Note sui carmi 210-214 R (= 201-205 Sh. B.) dell’Anthologia Salmasiana." AL. Rivista di studi di Anthologia Latina 1 (January 2010): 147–61. http://dx.doi.org/10.1484/j.alat.5.130583.

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6

Ferdous, J., N. Sharmin, A. Begum, and A. Begum. "Airborne Radioactivity in Hot Lab of Nuclear Medicine." Journal of Scientific Research 9, no. 2 (April 20, 2017): 159–66. http://dx.doi.org/10.3329/jsr.v9i2.29873.

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In this study, identification and measurement of gamma emitting radionuclides contaminant in air inside the hot lab at the Institute of Nuclear Medicine have been carried out. Air particulate collection has been performed by suction of indoor air through filter paper using Staplex air sampler. The radioactivities of Pb-212, Pb-214, Ac-228, Bi-214, K-40, I-131 and Tc-99m captured by the filter paper were assessed using gamma-ray spectrometry. The observed activities of natural radionuclides in air samples ranged from 0.59 to 295 mBq/m3 with average 143±0.003 mBq/m3 for Pb-212; 13.55 to 1911 mBq/m3 with average 402±0.007 mBq/m3 for Pb-214; 0.69 mBq/m3 to 571 mBq/m3 with average 57.33±0.009 mBq/m3 for Ac-228; 7.85 to 2192 mBq/m3 with average 543±0.014 mBq/m3 for Bi-214 and from 9.89 mBq/m3 to 256 mBq/m3 with average 92.9±0.052 mBq/m3 for K-40. The activities of artificial radionuclides in air filter ranged from 0.19 to 60.67 mBq/m3 with average 6.4±0.0 mBq/m3 for I-131; 0.25 to 40.27 mBq/m3 with average 4.17±0.0 mBq/m3 for Tc-99m. The activity of I-131 is compared with the reported values of other countries of the world. This demonstrated that the work place condition is satisfactory and the level of protection provided to the worker is sufficient.
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7

TANAHASHI, Hiroshi, and Takeshi TABIRA. "Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domains." Biochemical Journal 367, no. 3 (November 1, 2002): 687–95. http://dx.doi.org/10.1042/bj20020562.

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Human Fe65L2 is a member of the Fe65 protein family, which interacts with amyloid precursor protein (APP). Fe65L2 contains an N-terminal WW (Trp-Trp) domain followed by two phosphotyrosine-interaction domains, and consists of 486 amino acids. In the present study, we cloned and characterized two novel isoforms of Fe65L2, designated I-214 and I-245, which are produced by alternative splicing of the RNA. The splicing events disrupt the ability to bind with APP and low-density-lipoprotein-receptor-related protein. Fe65L2 was highly expressed in the brain, whereas I-214 and I-245 were expressed in various tissues. In HEK-293 cells, Fe65L2 was expressed in the nucleus and cytosol, whereas I-245 and I-214 were localized exclusively to the nucleus. The ratio of I-214 to Fe65L2 mRNA was increased by apoptotic stimuli. Although the overexpression of either Fe65L2 or I-214 did not significantly affect the half-life and maturation of APP, or the secretion of secreted APP, the secretion of β-amyloid peptide (Aβ)40 and Aβ42 was increased by overexpression of Fe65L2, but not by that of I-214. These results suggest that Fe65L2 affects Aβ production and a possible regulation of Fe65L2 function by alternative splicing.
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8

Bellido Díaz, José Antonio. "Estacio, Tebaida I 214-218: una oculta alusión al cíclope Pyracmon." Emerita 82, no. 2 (December 30, 2014): 291–312. http://dx.doi.org/10.3989/emerita.2014.05.1325.

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9

Parker, Alex, Catherine Rees, Jane Clarke, Walker H. Busby, and David R. Clemmons. "Binding of Insulin-like Growth Factor (IGF)–Binding Protein-5 to Smooth-Muscle Cell Extracellular Matrix Is a Major Determinant of the Cellular Response to IGF-I." Molecular Biology of the Cell 9, no. 9 (September 1998): 2383–92. http://dx.doi.org/10.1091/mbc.9.9.2383.

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Insulin-like growth factor–binding protein-5 (IGFBP-5) has been shown to bind to fibroblast extracellular matrix (ECM). Extracellular matrix binding of IGFBP-5 leads to a decrease in its affinity for insulin-like growth factor-I (IGF-I), which allows IGF-I to better equilibrate with IGF receptors. When the amount of IGFBP-5 that is bound to ECM is increased by exogenous addition, IGF-I’s effect on fibroblast growth is enhanced. In this study we identified the specific basic residues in IGFBP-5 that mediate its binding to porcine smooth-muscle cell (pSMC) ECM. An IGFBP-5 mutant containing alterations of basic residues at positions 211, 214, 217, and 218 had the greatest reduction in ECM binding, although three other mutants, R214A, R207A/K211N, and K202A/R206N/R207A, also had major decreases. In contrast, three other mutants, R201A/K202N/R206N/R208A, and K217N/R218A and K211N, had only minimal reductions in ECM binding. This suggested that residues R207 and R214 were the most important for binding, whereas alterations in K211 and R218, which align near them, had minimal effects. To determine the effect of a reduction in ECM binding on the cellular replication response to IGF-I, pSMCs were transfected with the mutant cDNAs that encoded the forms of IGFBPs with the greatest changes in ECM binding. The ECM content of IGFBP-5 from cultures expressing the K211N, R214A, R217A/R218A, and K202A/R206N/R207A mutants was reduced by 79.6 and 71.7%, respectively, compared with cells expressing the wild-type protein. In contrast, abundance of the R201A/K202N/R206N/R208A mutant was reduced by only 14%. Cells expressing the two mutants with reduced ECM binding had decreased DNA synthesis responses to IGF-I, but the cells expressing the R201A/K202N/R206N/R208A mutant responded well to IGF-I. The findings suggest that specific basic amino acids at positions 207 and 214 mediate the binding of IGFBP-5 to pSMC/ECM. Smooth-muscle cells that constitutively express the mutants that bind weakly to ECM are less responsive to IGF-I, suggesting that ECM binding of IGFBP-5 is an important variable that determines cellular responsiveness.
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10

Petráš, R., J. Mecko, and V. Nociar. "Models of assortment yield tables for poplar clones." Journal of Forest Science 54, No. 5 (May 22, 2008): 227–33. http://dx.doi.org/10.17221/3/2008-jfs.

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The results of research on the production of raw timber assortments for the stands of poplar clones Robusta and I-214 in Slovakia are presented in this paper. Models of assortment yield tables were constructed, separately for each clone, in dependence on the yield class and stand age. The construction was based on the models of yield tables, stand assortment tables, models of external quality and damage to stems. Robusta clone produces by about 15–20% higher proportions of the highest quality assortments than I-214 clone. I-214 clone produces faster and higher proportions of average- and below-average quality assortments.
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11

IULIETTO, Maria Nicole. "Allusioni al mito di Didone nel Carme del pescatore sacrilego (21 R = 8 SB, vv. 212-214)." AL. Rivista di studi di Anthologia Latina 2 (January 2011): 43–56. http://dx.doi.org/10.1484/j.alat.5.130545.

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12

MARKÓ, Gábor, László BEJÓ, and Péter TAKÁTS. "The applicability of I-214 hybrid poplar as Cross-Laminated Timber raw material." Wood Science = Faipar 63, no. 2 (October 30, 2015): 36–41. http://dx.doi.org/10.14602/woodsci.2015.2.42.

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<p class="p1">A többrétegű keresztirányú ragasztott tömörfa szerkezeti panel (CLT) a könnyűszerkezetes építés viszonylag új alapanyaga, mely hazánkban még nem elterjedt. Elterjedését segítené, ha ezt az építőelemet hazai alapanyagokból is gyártani lehetne. Kutatásunk célja a CLT elemek hazai nemesnyár alapanyagból való gyárthatóságának vizsgálata volt. Ennek érdekében egy háromrétegű panel gyártására és hajlítóvizsgálatára került sor, olasz nyár alapanyagból, poliuretán ragasztóanyaggal. A vizsgálati eredmények azt mutatják, hogy az olasz nyár CLT szilárdsági tulajdonságai megfelelőek az alacsonyabb szilárdsági kategóriájú fenyő faanyagnak, azonban a rugalmassági modulusz értékei elmaradnak a kívánalmaktól. A nyár alapanyag alkalmas lehet CLT gyártásra, de csak a lamellák előzetes roncsolásmentes minősítésével, és a jobb anyagok kiválogatásával, vagy másodlagos nyersanyagként a fenyő faanyag mellett.</p>
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13

Cañete-Salinas, Paulo, Francisco Zamudio, Marco Yañez, Héctor Valdés-Gómez, Cristian Espinosa, Jaime Venegas, Luis Retamal, Javier Gyenge, and César Acevedo-Opazo. "Water consumption and preliminary crop coefficients of two Populus ×canadensis clones (‘I-214’ and ‘I-488’) grown at low planting density." Forest Systems 30, no. 1 (March 9, 2021): eSC01. http://dx.doi.org/10.5424/fs/2021301-17276.

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Aim of study: The productivity of poplar plantations in Mediterranean climates might be reduced due to lower precipitations in a climate change scenario. Therefore, understanding the water consumption in these plantations is essential for their management. The objective of this study was to estimate water consumption and preliminary crop coefficients (kc) of two universally used poplar clones (Populus x Canadensis ‘I-214’ and ‘I-488’).Area of study: Central Chile (36º 05 'LS; 72º 47' LW; 470 m.a.s.l.).Materials and methods: Commercial stands of poplar clones established in 2009 and 2010 at low density (6×6 m) were used to experiment during the 2016-2017 growing season. In each of them, water balance was measuring, by determining evaporation using micro lysimeters and transpiration using the sap flow. Additionally, the water status and the leaf area index (LAI) were measured to understand the behaviour of both clones.Main results: Although the water supplied to both clones was the same, the transpiration (T) was higher for ‘I-488’ than ‘I-214’, at those moments in which the evapotranspiration (ETr) and the vapour pressure deficit (VPD) was higher. On the other hand, differences were observed in plant water status, ‘I-488’ had more negative xilematic water potential (Ψx) compared to ‘I-214’. In turn, I-214 proved to have a higher Leaf Area Index (LAI) than I-488 and grew more during the season, refuting its greater efficiency.Research highlights: These results allow characterizing the water behaviour of both clones in Mediterranean climate condition, but it is necessary to extend the study to more seasons and different age ranges.Keywords: Crop coefficient; water consumption; water balance; poplar.
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14

Petráš, R., J. Mecko, and V. Nociar. "Quality of wood in the stands of poplar clones." Journal of Forest Science 54, No. 1 (January 17, 2008): 9–16. http://dx.doi.org/10.17221/791-jfs.

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The results obtained in research on the quality of raw timber by means of the structure of assortments for the stands of poplar clones Robusta and I-214 are presented in the paper. Models for an estimation of the structure of basic assortments of poplar stands were constructed separately for each clone in dependence on mean diameter, quality of stems, and damage to stems in the stand. The clone Robusta has higher proportions of higher-quality assortments than the clone I-214. The accuracy of models was determined on empirical material. It was confirmed by statistical tests that the models did not have a systematic error. The relative root mean-square error for main assortments of the clone I-214 is 15–27% and Robusta 13–24%.
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15

Kouns, WC, B. Steiner, TJ Kunicki, S. Moog, J. Jutzi, LK Jennings, JP Cazenave, and F. Lanza. "Activation of the fibrinogen binding site on platelets isolated from a patient with the Strasbourg I variant of Glanzmann's thrombasthenia." Blood 84, no. 4 (August 15, 1994): 1108–15. http://dx.doi.org/10.1182/blood.v84.4.1108.1108.

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Abstract One proposed ligand binding site on platelet integrin alpha IIb beta 3 is the region of the beta 3 subunit encompassing amino acids 211–221. However, we recently showed that synthetic peptides corresponding to amino acids 211–221 inhibit fibrinogen binding to alpha IIb beta 3 by binding to alpha IIb beta 3 and not to fibrinogen. In this study, we show that AP6, a monoclonal antibody (MoAb) directed against amino acids 214–221 of beta 3, bound to immobilized active alpha IIb beta 3 but did not inhibit fibrinogen binding to the complex. We then determined whether nonfunctional alpha IIb beta 3 on platelets with a beta 3 Arg-214-->Trp mutation (Strasbourg I variant of Glanzmann's thrombasthenia or GTV) could be induced to aggregate after treatment with dithiothreitol (DTT). DTT has been shown to expose the fibrinogen receptor on normal platelets. DTT treatment of GTV platelets did result in the formation of the fibrinogen binding site as indicated by the binding of pI-55, an MoAb that only binds to the activated form of alpha IIb beta 3. Furthermore, DTT-treated GTV platelets aggregated in the presence of fibrinogen and divalent cations. This aggregation was inhibited by EDTA, RGDS, and the selective alpha IIb beta 3 antagonist, Ro 43–5054. These data show that Arg-214 of beta 3 is not required for fibrinogen binding or for platelet aggregation. However, this amino acid appears to be critical for the formation and for the maintenance of the correct tertiary structure of the fibrinogen binding site on alpha IIb beta 3.
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16

Kouns, WC, B. Steiner, TJ Kunicki, S. Moog, J. Jutzi, LK Jennings, JP Cazenave, and F. Lanza. "Activation of the fibrinogen binding site on platelets isolated from a patient with the Strasbourg I variant of Glanzmann's thrombasthenia." Blood 84, no. 4 (August 15, 1994): 1108–15. http://dx.doi.org/10.1182/blood.v84.4.1108.bloodjournal8441108.

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One proposed ligand binding site on platelet integrin alpha IIb beta 3 is the region of the beta 3 subunit encompassing amino acids 211–221. However, we recently showed that synthetic peptides corresponding to amino acids 211–221 inhibit fibrinogen binding to alpha IIb beta 3 by binding to alpha IIb beta 3 and not to fibrinogen. In this study, we show that AP6, a monoclonal antibody (MoAb) directed against amino acids 214–221 of beta 3, bound to immobilized active alpha IIb beta 3 but did not inhibit fibrinogen binding to the complex. We then determined whether nonfunctional alpha IIb beta 3 on platelets with a beta 3 Arg-214-->Trp mutation (Strasbourg I variant of Glanzmann's thrombasthenia or GTV) could be induced to aggregate after treatment with dithiothreitol (DTT). DTT has been shown to expose the fibrinogen receptor on normal platelets. DTT treatment of GTV platelets did result in the formation of the fibrinogen binding site as indicated by the binding of pI-55, an MoAb that only binds to the activated form of alpha IIb beta 3. Furthermore, DTT-treated GTV platelets aggregated in the presence of fibrinogen and divalent cations. This aggregation was inhibited by EDTA, RGDS, and the selective alpha IIb beta 3 antagonist, Ro 43–5054. These data show that Arg-214 of beta 3 is not required for fibrinogen binding or for platelet aggregation. However, this amino acid appears to be critical for the formation and for the maintenance of the correct tertiary structure of the fibrinogen binding site on alpha IIb beta 3.
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17

Hsu, Cheng-En, Chao-Ping Chen, Shun-Ping Wang, Jen-Ting Huang, Kwok-Man Tong, and Kui-Chou Huang. "Validation and modification of the Coronal Plane Alignment of the Knee classification in the Asian population." Bone & Joint Open 3, no. 3 (March 1, 2022): 211–17. http://dx.doi.org/10.1302/2633-1462.33.bjo-2022-0001.r1.

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Aims The Coronal Plane Alignment of the Knee (CPAK) classification is a simple and comprehensive system for predicting pre-arthritic knee alignment. However, when the CPAK classification is applied in the Asian population, which is characterized by more varus and wider distribution in lower limb alignment, modifications in the boundaries of arithmetic hip-knee-ankle angle (aHKA) and joint line obliquity (JLO) should be considered. The purposes of this study were as follows: first, to propose a modified CPAK classification based on the actual joint line obliquity (aJLO) and wider range of aHKA in the Asian population; second, to test this classification in a cohort of Asians with healthy knees; third, to propose individualized alignment targets for different CPAK types in kinematically aligned (KA) total knee arthroplasty (TKA). Methods The CPAK classification was modified by changing the neutral boundaries of aHKA to 0° ± 3° and using aJLO as a new variable. Radiological analysis of 214 healthy knees in 214 Asian individuals was used to assess the distribution and mean value of alignment angles of each phenotype among different classifications based on the coronal plane. Individualized alignment targets were set according to the mean lateral distal femoral angle (LDFA) and medial proximal tibial angle (MPTA) of different knee types. Results A very high concentration, 191 from 214 individuals (89.3%), were found in knee types with apex distal JLO when the CPAK classification was applied in the Asian population. By using aJLO as a new variable, the high distribution percentage in knee types with apex distal JLO decreased to 125 from 214 individuals (58.4%). The most common types in order were Type II (n = 70; 32.7%), Type V (n = 55; 25.7%), and Type I (n = 46; 21.5%) in the modified CPAK classification. Conclusion The modified CPAK classification corrected the uneven distribution when applying the CPAK classification in the Asian population. Setting individualized TKA alignment targets according to CPAK type may be a practical method to recreate optimal LDFA and MPTA in KA-TKA. Cite this article: Bone Jt Open 2022;3(3):211–217.
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18

Paniagua, Sergio, Alba Prado-Guerra, Ana Isabel Neto, Teresa Nunes, Luís Tarelho, Célia Alves, and Luis Fernando Calvo. "Influence of Varieties and Organic Fertilizer in the Elaboration of a New Poplar-Straw Pellet and Its Emissions in a Domestic Boiler." Energies 13, no. 23 (November 30, 2020): 6332. http://dx.doi.org/10.3390/en13236332.

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Pollutants resulting from domestic combustion would have harmful effects on public health, causing disturbances in the atmosphere chemistry and the climate. In this work, the emissions from the combustion of pellets made of 80% poplar (organically fertilized) and 20% cereal straw (Triticum aestivum) have been analysed. Poplar wood from I-214 and AF-8 clones was obtained from fertilized and non-fertilized plots (CONTROL). Dairy wastewater treatment (MUD) and dehydrated sewage sludge (BIOSOLIDS) were the fertilizers employed. BIOSOLIDS-I214 pellets had lower quality standards, so its combustion was omitted. A flue gas sample was sampled together with the particles emitted. The I-214 MUD sample had the highest emitted CO value (1505 mg/MJ). Regarding HCl emission factors, there was a homogeneity in the results linked with the Cl content present in the raw material. A higher particle emission was associated with pellets with higher ash content. Particles were composed mainly for elemental carbon (26–80 mg/MJ), except I-214 MUD. I-214 pellets had the indicators of incomplete combustion and, therefore, major contaminants emission and major environmental impact. Thus, both the poplar clone and the organic fertilizer influenced the parameters and emissions analysed. Therefore, special attention must be paid to both characteristics.
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19

Casado, Milagros, Luis Acuña, Luis-Alfonso Basterra, Gemma Ramón-Cueto, and Daniel Vecilla. "Grading of structural timber of Populus × euramericana clone I-214." Holzforschung 66, no. 5 (July 1, 2012): 633–38. http://dx.doi.org/10.1515/hf-2011-0153.

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Abstract Grading tests were performed on 338 poplar wood samples (Populus × euramericana I-214) with dimensions of 150×50 mm2, 150×80 mm2, and 200×100 mm2 prepared for structural utilization. The non-destructive testing methods included ultrasound (Sylvatest) and induced vibrations (Portable Lumber Grader) combined with visual grading criteria. Additionally, screw withdrawal resistance was tested by the instrument Fakopp. These results were compared with those obtained by a four-point bending test according to the EN 408 (2004) standard. Ultrasound and induced vibrations overestimated the quality of this type of wood. Correlation equations are proposed to determine the true characteristics for each testing method. It can be concluded that poplar timber from clone I-214 has acceptable flexural strength, but a comparatively low elastic modulus, whereby it is not graded within a high strength class according to the EN 338 (2009) standard.
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20

Rescalvo, Francisco J., Leandro Morillas, Ignacio Valverde-Palacios, and Antolino Gallego. "Acoustic emission in I-214 poplar wood under compressive loading." European Journal of Wood and Wood Products 78, no. 4 (May 22, 2020): 723–32. http://dx.doi.org/10.1007/s00107-020-01536-7.

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21

De Pascale, F., R. Muscariello, G. Zampa, G. De Filippo, D. Rendina, and P. Strazzullo. "Caratteristiche cliniche dei pazienti con sindrome metabolica e nefrolitiasi recidivante da ossalato di calcio." Giornale di Clinica Nefrologica e Dialisi 24, no. 4 (January 26, 2018): 19–23. http://dx.doi.org/10.33393/gcnd.2012.1168.

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La sindrome metabolica è un fattore di rischio per nefrolitiasi. Questo studio è stato effettuato per valutare il profilo clinico e biochimico di pazienti con nefrolitiasi recidivante da ossalato di calcio e sindrome metabolica. Sono stati arruolati un totale di 526 calcolotici, 184 dei quali con sindrome metabolica, e 214 controlli. I calcolotici con sindrome metabolica hanno mostrato un'escrezione di sodio superiore [media (95% intervallo di confidenza), 196 (176-218) vs 160 (150-168) mmol/24h; p
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Zumalde, Imanol. "Santos Zunzunegui, <em>Imagen sobre imagen. Mis Historias del Cine I</em>." EU-topías. Revista de interculturalidad, comunicación y estudios europeos 22 (December 30, 2021): 201. http://dx.doi.org/10.7203/eutopias.22.22944.

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Polak, Maurice V. "Case C-214/89, Powell Duffryn PLC v. Wolfgang Petereit, Judgment of 10 March 1992." Common Market Law Review 30, Issue 2 (April 1, 1993): 406–19. http://dx.doi.org/10.54648/cola1993022.

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Hollifield, Ian E., Natalya I. Motyka, Sydney R. Stewart, Michelle D. Blyth, Kaylynn A. Fernando, Kristen L. Clement, and Jacob P. Bitoun. "Heat-Stable Enterotoxin Secretions Assessed via ICP-MS Reveal Iron-Mediated Regulation of Virulence in CFA/I- and CS6-Expressing ETEC Isolates." Cells 12, no. 4 (February 10, 2023): 567. http://dx.doi.org/10.3390/cells12040567.

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Enterotoxigenic Escherichia coli (ETEC) are a significant cause of childhood diarrhea in low-resource settings. ETEC are defined by the production of heat-stable enterotoxin (ST) and/or heat-labile enterotoxin (LT), which alter intracellular cyclic nucleotide signaling and cause the secretion of water and electrolytes into the intestinal lumen. ETEC take cues from chemicals (e.g., glycans, bile salts, and solutes) that may be liberated following enterotoxin activity to recognize entrance into the host. ETEC then alter the expression of surface adhesins called colonization factors (CFs) to attach to the intestinal epithelium, proliferate, and cause disease. Here, we used an in vivo model of oral ST intoxication to determine its impact on luminal ion concentrations via ICP-MS. We also used functional assays, including Western blots, qPCR, and toxin activity assays, to assess the impact of luminal ion flux on CF and toxin expression. Finally, we assessed ETEC strains with CFs CFA/I or CS6 in a streptomycin mouse model of ETEC colonization. ST causes rapid and significant increases in luminal chloride but significant decreases in luminal magnesium and iron. We confirmed that increased sodium chloride suppresses CFA/I production in ETEC H10407 but does not affect CS6 production in ETEC 214-4. CFA/I production in ETEC H10407 is increased when magnesium becomes limiting, although it does not affect CS6 production in ETEC 214-4. Iron restriction via deferoxamine induces CFA/I expression in ETEC H10407 but not CS6 expression in ETEC 214-4. We demonstrate that ST production is suppressed via iron restriction in H10407, 214-4, and over 50 other ETEC clinical isolates. Lastly, we demonstrate that the iron restriction of mice using oral deferoxamine pre-treatment extends the duration of ETEC H10407 (CFA/I+) fecal shedding while accelerating ETEC 214-4 (CS6+) fecal shedding. Combined, these data suggest that enterotoxins modulate luminal ion flux to influence ETEC virulence including toxin and CF production.
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Galić, Zoran, Alen Kiš, Irina V. Andreeva, Zoran Novačić, Anđelina Gavranović, Miljan Samardžić, and Radenko Ponjarac. "Prostorna analiza tala i utjecaj na produktivnost u gospodarskoj jedinici Mužljanski rit." Šumarski list 145, no. 9-10 (October 26, 2021): 456–57. http://dx.doi.org/10.31298/sl.145.9-10.3.

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The paper presents analysis of soil spatial distribution and productivity of Populus x euramericana I-214 forest cultures in forest management unit (hereinafter: FMU) Muzljanski rit. Soil cover in the FMU is heterogeneous in relation to position and altitude in floodplain. Analysis were conducted on eugley and humogley soil types. Eugley, soil type, was delineated according to physiologically active soil depth as &#945;, &#946; or &#946;/&#947; gley soils and humogley was delineated as one soil unit. Cultures of the poplar clones Populus x euramericana I-214 are found on at least two but usually more different site types within the same forest management section (18.43 %). Single forest management section is a by definition a single forest spatial unit having similar ecologic factors. Aim of our research was to enable consistent forest section delineation, based on the interaction of soil productivity properties and distribution as well as Populus x euramericana I-214 productivity dataset. Based on our anaysis (spatial analysis of raster layers of soil systematic unit distribution-soil subunit, digital elevation model and productivity according to inner delineation of FMU Muzljanski rit), the resuts show eugley share in lower systematic soil unit. The results show contribution of lower systematic units of eugley in forest managemet section/culture. We found a raising trend of &#945; and &#946;-gley, as well as humogley. On one side the higher contribution of this sistematic units indicates reduction in the forest culture yield. On the other side higher contribution of &#946;/&#947; gley indicates an increase of culture yeald. The Populus x euramericana I-214 cultures are spatialy concentrated, extending over soil units with different characteristics, pointing in alternative economicaly justified section delineation, based on the soil types.
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Molina, R., X. Filella, M. D. Torres, A. M. Ballesta, P. Mengual, A. Cases, and A. Balaque. "SCC antigen measured in malignant and nonmalignant diseases." Clinical Chemistry 36, no. 2 (February 1, 1990): 251–54. http://dx.doi.org/10.1093/clinchem/36.2.251.

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Abstract SCC antigen was measured in the serum of 214 patients with benign diseases and in 251 patients with various cancers. With 2.5 micrograms/L as the upper normal limit for serum, values were positive in 2.9% of 69 healthy subjects (I), 29.0% of 214 patients with benign pathologies (II), and 41% of 217 patients with active cancer (III). The highest values in group II were for patients in renal failure (64%) or with lung diseases (40%) or head-and-neck diseases (21.2%). Specificity of SCC increased (91.1%) when we excluded patients in renal failure or with creatinine values greater than 133 mumol/L. In group III, SCC values were abnormal in 57.7% of patients with squamous cell carcinoma, but in only 9.3% of those with other histological types (P less than 0.001). In squamous cell carcinoma of the lung, cervix, or head and neck, SCC values were related to tumor stage, values being highest in patients with metastases.
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Ismail, Asaad Hamid, and Mohamad S. Jaafar. "Impact Deposition of Radon Progeny (218Po ,214Po and 210Po) on the Surface of Human Blood: In Vitro Study." Applied Mechanics and Materials 110-116 (October 2011): 2004–9. http://dx.doi.org/10.4028/www.scientific.net/amm.110-116.2004.

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This work presented new irradiation technique to estimate the impact of radon's progeny deposition on the human blood surface on some blood diseases, using CR-39Nuclear Track Detectors (NTDs). The results show that the present design has good efficiency and the loss rate of radon concentration was a little. Amount of the loss of radon concentration during the process of mixing blood component did not affect on the efficiency of exposure technique. Therefore, method of mixing blood component process was successful. As well as, human blood exposure to radon gas (2210±5.1Bq/m3) make thrombocytopenia, and no effect on red blood cell. And rate of radon absorbed dose into the human blood samples is high at 20 minutes.
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Avtzis, N. D. "Development of Leucoma salicis (L.) (Lepidoptera: Lymantriidae) on Populus alba (L.) and Poplar Clone “I-214”." ENTOMOLOGIA HELLENICA 8 (June 1, 2017): 25. http://dx.doi.org/10.12681/eh.13977.

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Tests were made to determine if the phytophagous insect Leucoma salicis (L.) (Le­pidoptera: Lymantriidae), preferred Populus alba (L.) or Poplar Clone “I-214” as its host. These tests were based on field observations in experimental plots at the nursery of the Forest Research Institute in Thessaloniki, N. Greece. The observations which continued for a two-year period (1984, 1985) corroborated the high resistance of P. alba to L. salicis. Rearing on this host-plant caused retarded growth, produced lower number of eggs, caused higher larval mortality and generally showed reduced development always, in comparison with the rearing of this insect on leaves of Clone “I-214”.
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McDermott, David F., Toni K. Choueiri, Robert J. Motzer, Osvaldo Rudy Aren, Saby George, Thomas Powles, Frede Donskov, et al. "CheckMate 214 post-hoc analyses of nivolumab plus ipilimumab or sunitinib in IMDC intermediate/poor-risk patients with previously untreated advanced renal cell carcinoma with sarcomatoid features." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 4513. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.4513.

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4513 Background: Patients (pts) with advanced renal cell carcinoma with sarcomatoid features (sRCC) have poor prognosis and suboptimal outcomes with anti-VEGF targeted therapy. Nivolumab plus ipilimumab (N+I) demonstrated superior objective response rate (ORR) and overall survival (OS) vs sunitinib (S) in previously untreated pts with International Metastatic RCC Database Consortium (IMDC) intermediate/poor (I/P)-risk, clear-cell, advanced RCC in the phase 3 CheckMate 214 trial. Methods: We performed a post-hoc exploratory analysis of N+I vs S in CheckMate 214 sRCC pts. The presence of sarcomatoid features was assessed by keyword search for “sarcomatoid” in pts with available local pathology reports accompanying pretreatment tumor samples. Results: 842 (77%) of 1096 intention-to-treat pts had local pathology reports available, including 112 randomized pts with I/P-risk sRCC (N+I, n = 60; S, n = 52). Baseline characteristics of sRCC pts were balanced between arms. Notably, 47% vs 53% of I/P-risk sRCC pts in the N+I and S arms had tumor PD-L1 expression ≥1% at baseline, which was higher than in all I/P-risk pts (N+I, 26% vs S, 29%). In descriptive analyses performed at a minimum follow-up of 30 months, confirmed ORR and complete response rate per investigator (RECIST v1.1), OS, and progression-free survival (PFS) per investigator were improved with N+I vs S in I/P-risk pts with sRCC (Table). No new safety signals were seen in sRCC pts. Conclusions: In this post-hoc descriptive subgroup analysis of CheckMate 214, N+I demonstrated promising efficacy and prolonged survival vs S, with consistent safety, in previously untreated, I/P-risk, advanced clear-cell RCC with sarcomatoid features. Prospective studies of N+I that include pts with sRCC are ongoing. Clinical trial information: NCT02231749. [Table: see text]
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Vasin, Goran. "Kosta Nikolić, A lost history – Serbia in the 20th century, Službeni glasnik, Beograd, 2016, pp. 418." ИСТРАЖИВАЊА, no. 28 (December 27, 2017): 212–14. http://dx.doi.org/10.19090/i.2017.28.212-214.

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Zlatković, Milica, Imola Tenorio-Baigorria, Tamás Lakatos, Tímea Tóth, András Koltay, Predrag Pap, Miroslav Marković, and Saša Orlović. "Bacterial Canker Disease on Populus × euramericana Caused by Lonsdalea populi in Serbia." Forests 11, no. 10 (October 9, 2020): 1080. http://dx.doi.org/10.3390/f11101080.

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Populus × euramericana (Dode) Guinier clone (cl.) “I-214” is a fast-growing interspecific hybrid between Eastern cottonwood (P. deltoides Bartr. ex Marsh) and European black poplar (Populus nigra L.). Populus × euramericana was introduced into Serbia in the 1950s and has become one of the most widely grown poplar species. In September 2019, cankers were observed on stems and branches of P. × euramericana cl. “I-214” trees in a two-year-old poplar plantation in the province of Vojvodina, Serbia. The canker tissue was soft and watery, and a colorless fluid that smelled rotten flowed from the cracks in the bark, suggesting possible bacterial disease. After two weeks, diseased trees experienced crown die-back and oozing of foamy, odorous exudates and this study aimed to identify the causal agent of the disease. Canker margins and exudates were collected from 20 symptomatic trees. The associated bacterium was isolated and identified using biochemical characteristics, phylogenetic analyses based on 16S rRNA gene sequences, and multilocus sequence analyses (MLSA) based on partial sequencing of three housekeeping genes (gyrB, infB, and atpD). The pathogen was identified as Lonsdalea populi. Pathogenicity tests were conducted on rooted cuttings of P. × euramericana cl. “I-214” in an environmental test chamber and demonstrated that the isolated bacterial strain was able to reproduce symptoms of softened, water-soaked cankers and exudation. To the best of our knowledge, this is the first report of L. populi causing bacterial canker disease on P. × euramericana cl. “I-214” in Serbia and in southeastern Europe (SEE). It is also the first report of a bacterial disease on hybrid poplars, including P. × euramericana in this country and in SEE. If the disease spreads into new areas, selection for L. populi resistance may need to be integrated into future poplar breeding programs.
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Bertozo, Luiza, Ernesto Tavares Neto, Leandro Oliveira, and Valdecir Ximenes. "Oxidative Alteration of Trp-214 and Lys-199 in Human Serum Albumin Increases Binding Affinity with Phenylbutazone: A Combined Experimental and Computational Investigation." International Journal of Molecular Sciences 19, no. 10 (September 21, 2018): 2868. http://dx.doi.org/10.3390/ijms19102868.

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Human serum albumin (HSA) is a target for reactive oxygen species (ROS), and alterations of its physiological functions caused by oxidation is a current issue. In this work, the amino-acid residues Trp-214 and Lys-199, which are located at site I of HSA, were experimentally and computationally oxidized, and the effect on the binding constant with phenylbutazone was measured. HSA was submitted to two mild oxidizing reagents, taurine monochloramine (Tau-NHCl) and taurine dibromamine (Tau-NBr2). The oxidation of Trp-214 provoked spectroscopic alterations in the protein which were consistent with the formation of N′-formylkynurenine. It was found that the oxidation of HSA by Tau-NBr2, but not by Tau-NHCl, provoked a significant increase in the association constant with phenylbutazone. The alterations of Trp-214 and Lys-199 were modeled and simulated by changing these residues using the putative oxidation products. Based on the Amber score function, the interaction energy was measured, and it showed that, while native HSA presented an interaction energy of −21.3 kJ/mol, HSA with Trp-214 altered to N′-formylkynurenine resulted in an energy of −28.4 kJ/mol, and HSA with Lys-199 altered to its carbonylated form resulted in an energy of −33.9 kJ/mol. In summary, these experimental and theoretical findings show that oxidative alterations of amino-acid residues at site I of HSA affect its binding efficacy.
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Andrasev, Sinisa, Savo Roncevic, Milivoj Vuckovic, Martin Bobinac, Milorad Danilovic, and Gojko Janjatovic. "Elements of structure and productivity of clone I-214 (Populus×euramericana (Dode) Guinier) plantations on the river Sava alluvium." Bulletin of the Faculty of Forestry, no. 101 (2010): 7–24. http://dx.doi.org/10.2298/gsf1001007a.

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Two experimental plantations of Euramerican poplar (Populus?euramericana (Dode) Guinier) - clone I-214 were researched on the river Sava alluvium in Srem. Three sample plots were established in each of the plantations, aged 31 years. The soil type was humofluvisol (alluvial semigley), planting space 6?6 m. The plantations were established with 278 rooted cuttings per hectare, and the number of trees at the age of 31 accounted for 46.5-60.6%. The constructed height curves, mean stand height (hg) and upper (hg20%) heights show that the study plantations were established on different site classes, which was significantly reflected on other plantation growth elements and productivity. However, there was no significant effect of site class on the variability (sd and cv) and shape of diameter structure (?3 and ?4). The constructed models of diameter structure for each site class (by Weibull function) differ by location parameter (a), and do not differ by parameter of scale (b) and shape (c). The tree and plantation growth elements show a high production potential of the clone I-214 which indicates that, on optimal soils and with the provided technological measures in the stage of nursery production and in the stage of plantation establishment, clone I-214 presents the good base for high production effects.
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Ištok, Iva, Tomislav Sedlar, Bogoslav Šefc, Tomislav Sinković, and Tomica Perković. "Physical Properties of Wood in Poplar Clones ’I-214’ and ’S1-8’." Drvna industrija 67, no. 2 (2016): 163–70. http://dx.doi.org/10.5552/drind.2016.1604.

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Vuckovic, Milivoj, Sinisa Andrasev, Savo Roncevic, and Martin Bobinac. "Effect of planting density on the development of tree and plantation volume of Populus x euramericana (Dode) Guinier cl. I-214." Bulletin of the Faculty of Forestry, no. 91 (2005): 77–87. http://dx.doi.org/10.2298/gsf0591077v.

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The effect of plantation density on the stem volume development phases of mean trees of Populus x euramericana (Dode) Guinier, cl. I-214 were studied in the test plantation aged 25 years with two different planting densities 4.25x4.25 m (treatment A) and 6.00x6.00 m (treatment B). The modeling of stem volume growth of mean trees enabled the identification of development phases based on biological laws. Different growth dynamics of mean trees of the clone I-214, depending on plantation density, had a clear effect on the beginning and the end of individual phases, i.e. subphases of development, as well as on the diameters, heights and volumes of mean trees at the end of each phase of volume development.
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Danilovic, Milorad, Dragan Rakovic, Dusan Isajev, and Slavica Antonic. "Comparative analysis of the assortment structure of poplar clones I-214 and Pannonia." Bulletin of the Faculty of Forestry, no. 122 (2020): 31–46. http://dx.doi.org/10.2298/gsf2022031d.

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Poplars occupy about 31.4 million ha in the world, while in Serbia poplars spread over the area of 48.000 ha. The subject of this research are artificially raised poplar plantations, consisting of poplar clone I-214 (Populus?euramericana (Dode) Guinier cl. I-214) and poplar clone Pannonia (Populus?euramericana (Dode) Guinier cl. Pannonia). Field activities of collecting data required for this research were conducted in two phases. The first phase of data collection included measurement of tree diameter. Also, the numbering, marking and recording of poplar rows, as well as each poplar in the row, was conducted. The second phase of data collection was conducted after the felling of trees that were selected for detailed measurement of the elements required for theoretical cross cutting. In accordance with the general principles of cross cutting, as well as the principles of maximum financial effect, the qualitative partition of trunks into several variants was performed. The classification of wood assortments was performed on the basis of SRPS wood standards. The share of technical wood for veneer (F and L class) in the analyzed poplar trees clone I-214 is 47.54% of the total volume of wood assortments. When it comes to the clone Pannonia, logs for cutting (quality class II), have the greatest share in total volume of wood assortments with 44.08. There is no statistically significant difference between the total volume and the value of the assortments of the two analyzed poplar clones, except when it comes to assortments for chemical exploitation where statistical differences exist.
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Hahn, Y. S., C. S. Hahn, V. L. Braciale, T. J. Braciale, and C. M. Rice. "CD8+ T cell recognition of an endogenously processed epitope is regulated primarily by residues within the epitope." Journal of Experimental Medicine 176, no. 5 (November 1, 1992): 1335–41. http://dx.doi.org/10.1084/jem.176.5.1335.

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Cytotoxic T lymphocytes (CTL) recognize short antigenic peptides associated with cell surface class I major histocompatibility complex (MHC) molecules. This association presumably occurs between newly synthesized class I MHC molecules and peptide fragments in a pre-Golgi compartment. Little is known about the factors that regulate the formation of these antigenic peptide fragments within the cell. To examine the role of residues within a core epitope and in the flanking sequences for the generation and presentation of the newly synthesized peptide fragment recognized by CD8+ CTL, we have mutagenized the coding sequence for the CTL epitope spanning residues 202-221 in the influenza A/Japan/57 hemagglutinin (HA). In this study over 60 substitution mutations in the epitope were tested for their effects on target cell sensitization using a cytoplasmic viral expression system. The HA202-221 site contains two overlapping subsites defined by CTL clones 11-1 and 40-2. Mutations in HA residues 204-213 or residues 210-219 often abolished target cell lysis by CTL clones 11-1 and 40-2, respectively. Although residues outside the core epitope did not usually affect the ability to be lysed by CTL clones, substitution of a Gly residue for Val-214 abolished lysis by clone 11-1. These data suggest that residues within a site that affect MHC binding and T cell receptor recognition appear to play the predominant role in dictating the formation of the antigenic complex recognized by CD8+ CTL, and therefore the antigenicity of the protein antigen presented to CD8+ T cells. Most alterations in residues flanking the endogenously expressed epitope do not appreciably affect the generation and recognition of the site.
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Huey, K. A., F. Haddad, A. X. Qin, and K. M. Baldwin. "Transcriptional regulation of the type I myosin heavy chain gene in denervated rat soleus." American Journal of Physiology-Cell Physiology 284, no. 3 (March 1, 2003): C738—C748. http://dx.doi.org/10.1152/ajpcell.00389.2002.

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Denervation (DEN) of rat soleus is associated with a decreased expression of slow type I myosin heavy chain (MHC) and an increased expression of the faster MHC isoforms. The molecular mechanisms behind these shifts remain unclear. We first investigated endogenous transcriptional activity of the type I MHC gene in normal and denervated soleus muscles via pre-mRNA analysis. Our results suggest that the type I MHC gene is regulated via transcriptional processes in the denervated soleus. Deletion and mutational analysis of the rat type I MHC promoter was then used to identify cis elements or regions of the promoter involved in this response. DEN significantly decreased in vivo activity of the −3,500, −2,500, −914, −408, −299, and −215 bp type I MHC promoters, relative to the α-skeletal actin promoter. In contrast, normalized −171 promoter activity was unchanged. Mutation of the βe3 element (−214/−190) in the −215 promoter and deletion of this element (−171 promoter) blunted type I downregulation with DEN. In contrast, βe3 mutation in the −408 promoters was not effective in attenuating the DEN response, suggesting the existence of additional DEN-responsive sites between −408 and −215. Western blotting and gel mobility supershift assays demonstrated decreased expression and DNA binding of transcription enhancer factor 1 (TEF-1) with DEN, suggesting that this decrease may contribute to type I MHC downregulation in denervated muscle.
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Spavento, Eleana, Mónica Murace, Luis Acuña, Silvia Estela Monteoliva, and Mª Teresa Troya. "Susceptibility of Populus x euramericana ‘I-214’ of Spanish origin to xylophagous attacks: durability tests for its possible inclusion in European standard." Forest Systems 28, no. 2 (August 5, 2019): e008. http://dx.doi.org/10.5424/fs/2019282-14660.

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Aim of study: to assess the natural durability of Populus x euramericana ‘I-214’ against xylophagous fungi and termites, and to carry out a macro-microscopic analysis of the alterations caused by each xylophagous agent in order to get the necessary information for its possible inclusion in existing European standards.Area of study: A 20-years-old commercial plantation Populus x euramericana‘I-214’ located in Quintanilla de Sollamas (42° 36′ 00″N - 05° 49′ 00″ W), Spanish community of Castile-LeonMaterial and methods: material sampling and selection was carried out following EN 350:2017 for commercial sawn timber. Poplar resistance to xylophagous basidiomycete, soft rot fungi and subterranean termites was determined according to CEN/TS 15083-1:2005, CEN/TS 15083-2:2005 and EN 117:2012, respectively. The durability and use classes were estimated according to EN 350:2016 and EN 335:2013, respectively. The anatomical studies were carried out with Optical and Scanning Electron Microscope. Material characterization was carried out by reference to Anagnost (1998) and Schwarze (2007).Main results: ‘I-214’ poplar wood proved to be “Not-durable” to the action of basidiomycetes, soft rot fungi and termites, use classes 1-2, and showed macro-microscopic evidence of these types of decay.Research highlights: the information obtained in this study would allow the inclusion of clone I-214 in the standard EN 350 and its explicit classification within it.Keywords: wood-decay fungi; termites; EN 350.Abbreviations used: TM: test material; RM: reference material; RH: relative humidity; ML: mass loss; mi: initial dry mass; mf: final dry mass; DC: durability class; OM: Optical Microscope; SEM: Scanning Electron Microscope; TS: transverse section samples; LS: longitudinal section samples; CI: robust confidence intervals; F: fibre; V: vessel; h: hole; t: erosion trough; R: radial parenchyma cell; ep: erosion pitting; Fc: fungal colonization; fr: fracture; c: cavity; b: bore hole; m: mycelium.
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Djukic, Matilda, Danijela Djunisijevic-Bojovic, Mihailo Grbic, Dragana Skocajic, Marija Markovic, and Sladjana Samuilov. "Ecophysiological properties of white and Canadian poplar in habitats with various water regimes." Bulletin of the Faculty of Forestry, no. 110 (2014): 73–85. http://dx.doi.org/10.2298/gsf1410073d.

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In this paper are presented the analyzes of some morphometric properties, leaves area stomata density and the intensity of leaves transpiration of white poplar, Populus alba L. and canadian poplar, Populus x canadensis Moench ?I 214? in populations at (1) flooded (wet) and (2) unflooded (dry) habitats on the Ada Ciganlija river island during the growing season. Six trees of each species from both habitats were selected, with similar height, age and physiological condition. The morphometric analysis of the analysed poplar species show that the type of habitat did not influence tree height and trunk as well as the leaves area. However, crown width and trunk diameter were greater in the wetter habitat. It was found that the intensity of transpiration of Populus x canadensis ?I 214? trees had higher average values (0,73 gH2Odm??h??) than white poplar (0,68 gH2Odm ??h??). Transpiration of both taxa was more intensive on the drier than on the flooded habitats. By analyzing the number and size of stomata on leaves of the investigated Populus x canadensis ?I 214? trees, it was found that stomata are more numerous but of smaller size on the leaves from drier habitats. It could be concluded that both species could have impact on microclimate conditions by increasing air moisture content and decreasing air temperature but Canadian comparing to white poplar, slightly greater. Increasing air temperature is a consequence of evident global climate change. Through transpiration plants reduce summer air temperature indirectly, by increasing its relative humidity.
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Huey, K. A., R. R. Roy, F. Haddad, V. R. Edgerton, and K. M. Baldwin. "Transcriptional regulation of the type I myosin heavy chain promoter in inactive rat soleus." American Journal of Physiology-Cell Physiology 282, no. 3 (March 1, 2002): C528—C537. http://dx.doi.org/10.1152/ajpcell.00355.2001.

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Chronic muscle inactivity with spinal cord isolation (SI) decreases expression of slow type I myosin heavy chain (MHC) while increasing expression of the faster MHC isoforms, primarily IIx. The purpose of this study was to determine whether type I MHC downregulation in the soleus muscle of SI rats is regulated transcriptionally and to identify cis-acting elements or regions of the rat type I MHC gene promoter involved in this response. One week of SI significantly decreased in vivo activity of the −3500-, −408-, −299-, −215-, and −171-bp type I MHC promoters. The activity of all tested deletions of the type I MHC promoter, relative to the human skeletal α-actin promoter, were significantly reduced in the SI soleus, except activity of the −171-bp promoter, which increased. Mutation of the βe3 element (−214/−190 bp) in the −215- and −408-bp promoters and deletion of this element (−171-bp promoter) attenuated type I downregulation with SI. Gel mobility shift assays demonstrated a decrease in transcription enhancer factor-1 binding to the βe3 element with SI, despite an increase in total binding to this region. These results demonstrate that type I MHC downregulation with SI is transcriptionally regulated and suggest that interactions between transcription enhancer factor-1 and the βe3 element are likely involved in this response.
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Walker, Joshua M., Annah S. Rolig, Deborah H. Charych, Ute Hoch, Melissa J. Kasiewicz, Daniel C. Rose, Michael J. McNamara, Ian F. Hilgart-Martiszus, and William L. Redmond. "NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8+T cell responses capable of curing multi-focal cancer." Journal for ImmunoTherapy of Cancer 8, no. 1 (May 2020): e000464. http://dx.doi.org/10.1136/jitc-2019-000464.

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BackgroundHigh-dose radiotherapy (RT) is known to be immunogenic, but is rarely capable of driving clinically relevant abscopal antitumor immunity as monotherapy. RT is known to increase antigen presentation, type I/II interferon responses, and immune cell trafficking to irradiated tumors. Bempegaldesleukin (NKTR-214) is a CD122-preferential interleukin 2 (IL-2) pathway agonist that has been shown to increase tumor-infiltrating lymphocytes, T cell clonality, and increase PD-1 expression. NKTR-214 has increased drug half-life, decreased toxicity, and increased CD8+T cell and natural killer cell stimulation compared with IL-2.MethodsAnimals bearing bilateral subcutaneous MCA-205 fibrosarcoma or CT26 colorectal tumors were treated with NKTR-214, RT, or combination therapy, and tumor growth of irradiated and abscopal lesions was assessed. Focal RT was delivered using a small animal radiation research platform. Peripheral and tumor-infiltrating immune phenotype and functional analyses were performed by flow cytometry. RNA expression profiling from both irradiated and abscopal lesions was performed using microarray.ResultsWe demonstrate synergy between RT of a single tumor and NKTR-214 systemic therapy resulting in dramatically increased cure rates of mice bearing bilateral tumors compared with RT or NKTR-214 therapy alone. Combination therapy resulted in increased magnitude and effector function of tumor-specific CD8+T cell responses and increased trafficking of these T cells to both irradiated and distant, unirradiated, tumors.ConclusionsGiven the increasing role of hypofractionated and stereotactic body RT as standard of care treatments in the management of locally advanced and metastatic cancer, these data have important implications for future clinical trial development. The combination of RT and NKTR-214 therapy potently stimulates systemic antitumor immunity and should be evaluated for the treatment of patients with locally advanced and metastatic solid tumors.
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43

Werner, Karel. "Lebensbilder deutscher Buddhisten. Ein bio-bibliographisches Handbuch. Band I: Die Gründer. Band II: Die Nachfolger. Edited by Hellmuth Hecker." Buddhist Studies Review 15, no. 1 (June 16, 1998): 129–31. http://dx.doi.org/10.1558/bsrv.v15i1.14832.

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Lebensbilder deutscher Buddhisten. Ein bio-bibliographisches Handbuch. Band I: Die Gründer. Band II: Die Nachfolger. Edited by Hellmuth Hecker. Universität Konstanz, Forschungsprojekt 'Buddhistischer Modernismus', Forschungsberichte 13-14, Konstanz 1996-7. 214 and 405 pp. No price given. ISBN 3-930959-09-7 and -10-0.
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44

Liu, Bin, You-Jun Tang, Lü-Ya Xing, Yu Xu, Shao-Qing Zhao, Yang Sun, and Jian Huang. "Triassic calc-alkaline lamprophyre dykes from the North Qiangtang, central Tibetan Plateau: evidence for a subduction-modified lithospheric mantle." Geological Magazine 159, no. 3 (November 24, 2021): 407–20. http://dx.doi.org/10.1017/s001675682100100x.

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AbstractPrimitive lamprophyres in orogenic belts can provide crucial insights into the nature of the subcontinental lithosphere and the relevant deep crust–mantle interactions. This paper reports a suite of relatively primitive lamprophyre dykes from the North Qiangtang, central Tibetan Plateau. Zircon U–Pb ages of the lamprophyre dykes range from 214 Ma to 218 Ma, with a weighted mean age of 216 ± 1 Ma. Most of the lamprophyre samples are similar in geochemical compositions to typical primitive magmas (e.g. high MgO contents, Mg no. values and Cr, with low FeOt/MgO ratios), although they might have experienced a slightly low degree of olivine crystallization, and they show arc-like trace-element patterns and enriched Sr–Nd isotopic composition ((87Sr/86Sr)i = 0.70538–0.70540, ϵNd(t) = −2.96 to −1.65). Those geochemical and isotopic variations indicate that the lamprophyre dykes originated from partial melting of a phlogopite- and spinel-bearing peridotite mantle modified by subduction-related aqueous fluids. Combining with the other regional studies, we propose that slab subduction might have occurred during Late Triassic time, and the rollback of the oceanic lithosphere induced the lamprophyre magmatism in the central Tibetan Plateau.
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Danilović, M., R. Sarić, V. Cirović, and V. Pudja. "The impact of pruning on tree development in poplar Populus × canadensis “I-214” plantations." iForest - Biogeosciences and Forestry 15, no. 1 (February 28, 2022): 33–37. http://dx.doi.org/10.3832/ifor3865-014.

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46

Danilovic, Milorad, and Gojko Janjatovic. "Assortment structure in poplar plantation Populus x euramerjcana I-214 based on European standard." Bulletin of the Faculty of Forestry, no. 91 (2005): 97–108. http://dx.doi.org/10.2298/gsf0591097d.

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Assortment structure in poplar plantation Populus x euramericana I-214 was obtained by European standard for round wood. Based on the data of theoretical cutting, the correlation between total volume of assortments and tree diameter at breast height was established. Model of the function representing the relation between total volume of assortments of superior quality and tree diameter is reciprocal. The relation between total volumes of normal-quality assortments can be represented by a logarithm model of the function, and the relation between total volume of assortments which cannot be classified into any quality class and tree diameter is best represented by a degree model. Knots up to the height of 6 m had a significant effect on the percentage of classes of superior quality. If the lower branches were pruned from standing trees up to the height of 6 m, the percentage of this class would increase averagely by 22.07%. This shows that pruning of lower branches is a very significant plantation tending measure and that it should be performed in time. Sweep also caused the decrease of percentage of superior assortments, but not to the expected degree, because the plantation is situated along the river Sava.
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47

Di Baccio, D., G. Galla, T. Bracci, A. Andreucci, G. Barcaccia, R. Tognetti, and L. Sebastiani. "Transcriptome analyses of Populus x euramericana clone I-214 leaves exposed to excess zinc." Tree Physiology 31, no. 12 (October 27, 2011): 1293–308. http://dx.doi.org/10.1093/treephys/tpr106.

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48

Čížková, L., V. Čížek, and H. Bajajová. "Growth of hybrid poplars in silviculture at the age of 6 years." Journal of Forest Science 56, No. 10 (September 30, 2010): 451–60. http://dx.doi.org/10.17221/26/2010-jfs.

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Growth and timber production of 28 poplar clones were evaluated. A set of clones was derived from<br />14 clones newly bred in Forestry and Game Management Research Institute in the Czech Republic, eight well-known cultivars of Populus &times; euroamericana planted in Europe and imported to the Czech Republic, two standard cultivars 'I-214' and 'Robusta' (Populus &times; euroamericana). Four clones of Populus deltoides were added to the test set. Tree spacing was 4 &times; 4 m. Stem diameter, tree height and stem volume production were evaluated in 6-years-old trees. Based on the results, it was concluded that the yield of four clones was higher than that of standard cultivar 'I-214'. Standing volume of two P. deltoides clones and one new Czech P. &times; euroamericana clone varied in the range of 77&ndash;121 m<sup>3</sup>&middot;ha&ndash;<sup>1</sup>.
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Livingston, Katherine. "In Search of Nature . Edward O. Wilson. Island/Shearwater, Washington, DC, 1996. x, 214 pp., illus. $19.95." Science 274, no. 5288 (November 1996): 734. http://dx.doi.org/10.1126/science.274.5288.734.d.

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50

Fisher, Laura. "Expression of concern: LncRNA CASC2 inhibits autophagy and promotes apoptosis in non-small cell lung cancer cells via regulating the miR-214/TRIM16 axis." RSC Advances 12, no. 10 (2022): 5890. http://dx.doi.org/10.1039/d2ra90006h.

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Expression of concern for ‘LncRNA CASC2 inhibits autophagy and promotes apoptosis in non-small cell lung cancer cells via regulating the miR-214/TRIM16 axis’ by Qian Li et al., RSC Adv., 2018, 8, 40846–40855, DOI: 10.1039/c8ra09573f.
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