Academic literature on the topic 'Hydroxyapatite/carbon composite'

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Journal articles on the topic "Hydroxyapatite/carbon composite"

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Yang, Li, and Zuli Mao. "Effect of SiC Particle Contents and Size on the Microstructure and Dissolution of SiC-Hydroxyapatite Coatings." Coatings 11, no. 10 (September 27, 2021): 1166. http://dx.doi.org/10.3390/coatings11101166.

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Carbon/carbon composites, when used as bone implant materials, do not adhere well to the bone tissues because of their non-bioactive characteristics. Therefore, we electro-deposited SiC-hydroxyapatite coatings (with an ultrasound-assisted step) on carbon/carbon composites. We analyzed how the content and size of the SiC particles affected the structure, morphology, bonding strength and dissolution of the SiC-hydroxyapatite coatings. The hydroxyapatite coating dissolution properties were assessed by the released Ca2+ and the weight loss. The SiC-hydroxyapatite coating on naked carbon/carbon composites showed a more compact microstructure in comparison to the hydroxyapatite coating on carbon/carbon composites. The reasons for the changes in the microstructure and the improvement in the adhesion of the coatings on C/C were discussed. Moreover, the addition of SiC particles increased the binding strengths of the hydroxyapatite coating on C/C composite, as well as reduced the dissolution rate of the hydroxyapatite coating.
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Kealley, Catherine S., Bruno A. Latella, Arie van Riessen, Margaret M. Elcombe, and Besim Ben-Nissan. "Micro- and Nano-Indentation of a Hydroxyapatite-Carbon Nanotube Composite." Journal of Nanoscience and Nanotechnology 8, no. 8 (August 1, 2008): 3936–41. http://dx.doi.org/10.1166/jnn.2008.188.

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The mechanical properties of pure synthetic hydroxyapatite and hydroxyapatite-carbon nanotube composites were examined. Vickers microhardness and nanoindentation using a Berkovich tipped indenter were used to determine the hardness, fracture toughness and Young's modulus of the pure hydroxyapatite matrix and the composite materials. Microscopy showed that for the composites produced the carbon nanotubes were present as discrete clumps. These clumps induced a detrimental effect on the hardness of the materials, while the fracture toughness values were not affected. This would be undesirable in terms of using the material for biomedical implant applications. It should be noted that the carbon nanotubes used contained free graphite. As the properties of the composite materials studied were not greatly improved over the matrix, it is speculated that if the graphite phase were removed from the reagent, this could in-turn enhance the properties of the material.
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Figueroa-Rosales, Edna X., Javier Martínez-Juárez, Esmeralda García-Díaz, Daniel Hernández-Cruz, Sergio A. Sabinas-Hernández, and Maria J. Robles-Águila. "Photoluminescent Properties of Hydroxyapatite and Hydroxyapatite/Multi-Walled Carbon Nanotube Composites." Crystals 11, no. 7 (July 17, 2021): 832. http://dx.doi.org/10.3390/cryst11070832.

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Hydroxyapatite (HAp) and hydroxyapatite/multi-walled carbon nanotube (MWCNT) composites were obtained by the co-precipitation method, followed by ultrasound-assisted and microwave radiation and thermal treatment at 250 °C. X-ray diffraction (XRD) confirmed the presence of a hexagonal phase in all the samples, while Fourier-transform infrared (FTIR) spectroscopy elucidated the interaction between HAp and MWCNTs. The photoluminescent technique revealed that HAp and the composite with non-functionalized MWCNTs present a blue luminescence, while the composite with functionalized MWCNTs, under UV-vis radiation shows an intense white emission. These findings allowed presentation of a proposal for the use of HAp and HAp with functionalized MWCNTs as potential materials for optoelectronic and medical applications.
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Li, Ying Hua, Li Yun Cao, Jian Feng Huang, and Xie Rong Zeng. "Preparation of Hydroxyapatite/Chitosan Biological Coatings on Carbon/Carbon Composites." Key Engineering Materials 434-435 (March 2010): 502–5. http://dx.doi.org/10.4028/www.scientific.net/kem.434-435.502.

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Hydroxyapatite/Chitosan (HAp/CS) bio-coatings were prepared on the surface of carbon/ carbon (C/C) composites by hydrothermal electrophoretic deposition, using sonochemical process resulted HAp nanoparticles, isopropyl alcohol and chitosan as raw materials. The influences of hydro- thermal conditions and deposition voltage on the microstructures and morphologies of the as-prepared coatings were investigated. It was shown that homogenous and dense HAp/CS coatings on C/C composites are obtained by hydrothermal electrophoretic deposition. With the increase of deposition voltage, density and homogeneity of the as-prepared HAp/CS composite coatings are well improved. Due to the growth of HAp nanoparticles in the hydrothermal condition, the subsequent heat treatment of the HAp/CS coatings is not needed.
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Kealley, Catherine, M. Elcombe, A. van Riessen, and Besim Ben-Nissan. "Neutron Characterisation of Hydroxyapatite Bioceramics." Key Engineering Materials 309-311 (May 2006): 61–64. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.61.

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This paper reports neutron diffraction data and its analysis that characterise a biocompatible hydroxyapatite composite material. The neutron data has elucidated the crystal structure, and enabled the positions of the hydrogen atoms to be determined. The data also shows the improvement of crystallinity during the heat treatment process. An extension of the work involved looking at a hydroxyapatite – carbon nanotube composite material, and neutron diffraction has shown that the retention of the carbon nanotubes in the composite material has been successful. The nanotubes have had no affect on the hydroxyapatite structure.
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Lu, Zhi Hua, Kang Ning Sun, and Dong Mei Zhao. "Reinforcement of Hydroxyapatite with Multi-Walled Carbon Nanotubes." Advanced Materials Research 306-307 (August 2011): 72–75. http://dx.doi.org/10.4028/www.scientific.net/amr.306-307.72.

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Multi-walled carbon nanotubes (MWNTs) reinforced hydroxyapatite (HA) composite was fabricated by in-situ method and followed by hot-pressing sintering; the influence of MWNTs’ content on the mechanical and microstructure properties was explored. The results show that adding MWNTs within a certain range could enhance the mechanical properties of HA matrix significantly. The maximal increment of the bending strength and fracture toughness of the composites, compared with the pure HA, were 157% and 171% respectively. XRD and TEM showed that the primary crystal phase of the composite was HA together with the diffraction peaks of carbon nanotube. By SEM, we found that MWNTs are homogeneously dispersed within grains or at grain boundaries of the HA matrix in composites which MWNTs’ content was not more than 15vol%, otherwise MWNTs tended to be agglomerated. The reinforcement mechanism was discussed based on the microstructure investigation. The broken nanotubes and pullout of MWNTs at interfaces were efficient in transferring the load from the HA matrix to the nanotubes, leading to the improvement of the mechanical properties.
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White, Ashley A., Alan H. Windle, Ian Kinloch, and Serena Best. "Preparation and Properties of Carbon Nanotube-Reinforced Hydroxyapatite." Key Engineering Materials 361-363 (November 2007): 419–22. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.419.

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Composites of hydroxyapatite (HA) and multiwalled carbon nanotubes (CNTs) have been prepared and characterised for potential application in major load-bearing medical devices. We have studied the effect of nanotube surface chemistry, composite preparation methods, and heat treatment conditions on the microstructure of the composites, dispersion of CNTs, and interaction between the HA and CNTs. The samples were characterised using SEM, XRD, FTIR, and BET surface area. It was found that, compared with pure HA, the composites had lower densities and higher surface areas. Additionally, functionalisation improved the dispersion of CNTs in the HA matrix and the interaction between the two phases.
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Ustundag, Cem Bulent. "Fabrication of porous hydroxyapatite-carbon nanotubes composite." Materials Letters 167 (March 2016): 89–92. http://dx.doi.org/10.1016/j.matlet.2015.12.135.

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Lee, Hae-Hyoung, Ueon Sang Shin, Jong-Eun Won, and Hae-Won Kim. "Preparation of hydroxyapatite–carbon nanotube composite nanopowders." Materials Letters 65, no. 2 (January 2011): 208–11. http://dx.doi.org/10.1016/j.matlet.2010.10.012.

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Liu, Jin Song, and Xiao Li Ji. "Hydroxyapatite–Carbon Nanotubes Composite Coatings on Ti Substrate." Advanced Materials Research 424-425 (January 2012): 86–89. http://dx.doi.org/10.4028/www.scientific.net/amr.424-425.86.

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Carboxyl multi-walled carbon nanotubes (MWCNTs) as the second phase in the hydroxyapatite(HA) composite coatings on Ti substrate, produced by a sol–gel route, were developed for biomedical applications. The crystallization of hydroxyapatite phase was investigated with X-ray diffraction(XRD) and the microstructure of the obtained composite coatings were studied by scanning electron microscopy (SEM). Bonding strength between coating and substrate were also investigated. The surface of the composite coatings were dense and uniform. The coatings had good adhesion to the substrate. As-prepared HA-MWCNTs composite coatings combining the osteconductive property of HA and the excellent mechanical property of MWCNTs will provide a promising material for potential bone replacements.
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Dissertations / Theses on the topic "Hydroxyapatite/carbon composite"

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Bell, Bryan Frederick. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-06072004-131058/unrestricted/bell%5Fbryan%5Ff%5F200405%5Fms.pdf.

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Bell, Bryan Frederick Jr. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/7962.

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FERRI, MICHELE. "HYDROXYAPATITE-BASED MATERIALS FOR ENVIRONMENTAL PROCESSES." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/815634.

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In this dissertation, hydroxyapatite-based and hydroxyapatite with carbon composite materials have been rationally designed, synthesized, characterized and applied to processes of environmental concern, namely wastewater remediation (as sorbents) and electrochemical CO2 reduction reaction, CO2RR (as electrocatalysts). Pristine hydroxyapatite (HAP, Ca10(PO4)6(OH)2) and composite HAP/carbon materials have been synthesized according to a simple wet co-precipitation route. Composition, structure and morphology of samples have been investigated by a plethora of physical-chemical techniques (i.e. ICP/OES elemental analyses, N2 adsorption/desorption isotherms, XRD, TEM (and STEM) imaging, TEM/EDX mapping, transmittance FT-IR and Raman spectroscopies, and XPS). Since adsorption onto materials’ surface is crucial in both sorption and catalytic applications, a special attention has been devoted to surface properties, determined by means of zeta potential measurements, gas-solid calorimetric/volumetric titrations, and liquid-solid volumetric titrations, thus assessing the amphoteric nature of HAP-based surfaces. At first, pristine pristine HAP has been studied as sorbent for the remediation of inorganic pollution in wastewater (i.e. heavy metal cations such as Cu(II), Pb(II), Cr(III), Ni(II) and Co(II)). Stirred batch adsorption tests and collection of adsorption isotherms in solutions containing both individual and mixtures of heavy metal cations allowed to quantitatively assess HAP sorption ability. Ad-hoc experiments (i.e. microcalorimetric adsorption isotherms) and physical-chemical investigation of metal-loaded samples shed light on the adsorption mechanisms of several polluting species onto HAP surface. Eco-friendly HAP/carbon composites from renewable resources have been instead applied to the remediation of more complex effluents, where simultaneous organic and inorganic pollution may occur. Thanks to their dual nature, HAP/carbon composites exerted outstanding adsorption performances towards both class of polluting species. Both in the form of pristine HAP and HAP/carbon composites, the sorbents exhibited a strict retention of adsorbed pollutants when undergoing leach testing, therefore ensuring no secondary pollution issues. In an exploratory study, HAP/carbon composites have been also implemented as modifiers in self-standing and mechanically stable electrodes for the electrochemical detection of heavy metal cations traces in waterbodies. Benefitting from the pronounced HAP affinity towards such species, encouraging results have been obtained on the detection of some benchmark pollutants, although the registered limits of detection (ca. one order of magnitude improvement to match legislative requirements) and linearity ranges currently limit HAP/carbon modified electrodes applications. Finally, during a 6-months stay at University of California Irvine (UCI), hosted by Prof. Plamen Atanassov group, HAP has been applied as dopant in CO2RR electrocatalysts. The peculiar ability of HAP amphoteric surface to adsorb and destabilize CO2 (i.e. breakage of its linearity) has been exploited in composite electrocatalysts, composed by copper nanoparticles (active phase) and HAP (dopant), supported on N-doped 3D assembly of graphene nanosheets (3D-GNS, carbonaceous support). When tested in a lab scale CO2 electrolyzer, HAP-doped electrocatalysts displayed a faradic efficiency (FE) towards CO2RR ≥ 80% throughout the whole potential range under investigation, minimizing parasitic Hydrogen Evolution Reaction (HER). Interestingly, HAP doping actually altered CO2RR product distribution: in particular, small quantities of C2+ products were produced under low applied overpotential while at higher voltage formate production was boosted. Product distribution alteration has been rationalized taking into account the ability of HAP acid-basic surface groups to stabilize CO2 reduction intermediate species, directing the the selectivity of electrochemical CO2RR processes. Overall, the present study demonstrates that the unique features of HAP make it a versatile material which may be applied for the protection of the environment at 360 degrees, from water to air remediation, as pristine and/or composite material, as sorbent and/or catalysts’ dopant.
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Oubenali, Mustapha. "Synthèse par dépôt chimique en phase vapeur catalytique (C-CVD) de nanostructures de carbone et leurs applications en catalyse et pour des matériaux composites." Thesis, Toulouse, INPT, 2011. http://www.theses.fr/2011INPT0058/document.

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Dans ce travail, nous décrivons les différentes formes, la structure, les propriétés et la croissance catalytique de nanotubes et nanofibres de carbone (Chapitre I). L'hydroxyapatite a été utilisée comme support de la phase active pour la synthèse de nanotubes de carbone multi-feuillet (MWCNTs) et de nanofibres de carbone (CNFs-H) par la technique de dépôt chimique en phase de vapeur catalytique (C-CVD) en lit fluidisé (Chapitre II). Après l'élimination du support par un simple lavage à l'acide chloridrique dilué, une étude théorique et expérimentale de l'oxydation de la surface de nanotubes de carbone par un traitement à l'acide nitrique a permis d'une part d'identifier et de quantifier les groupes formés à la surface de nanostructures carbonées et d'autre part de proposer un mécanisme pour la formation de ces groupes (Chapitre III). Les matériaux résultants après génération des fonctions carboxyliques de surface ont été utilisés comme support de catalyseur. L'hydrogénation du p-halogénonitrobenzène a été choisit comme réaction modèle pour comparer les performances catalytiques de catalyseurs à base de ruthénium en fonction de la nature du support utilisé, MWCNTs ou CNFs-H. L'influence de certains paramètres tels que la température, la nature du substrat et un traitement thermique du catalyseur (activation) est présentée. Une explication des performances catalytiques est proposée après caractérisation du catalyseur par MET, TPD, TPR et PZC (Chapitre IV). Les nanostructures carbonnées produites et caractérisées ont été utilisées comme charge de renforcement d'hydroxyapatites connue comme biomatériaux. Nous avons étudié en particulier la capacité de germination du phosphate octocalcique par la méthode de croissance cristalline à composition constante (C4) (Chapitre V)
In this work, we describe the different forms, the catalytic growth, the structure and properties of carbon nanotubes and nanofibres (Chapter I). Hydroxyapatite was used as catalyst support for the synthesis of multi-walled carbon nanotubes (MWCNTs) and nanofibres (CNFs) by catalytic chemical vapour deposition (C-CVD) in a fluidized bed reactor (Chapter II). After support removal by washing with diluted hydrochloric acid, a theoretical and experimental study of surface oxidation of carbon nanotubes by nitric acid treatment has been performed. It allows to identify and quantify the groups formed on the surface of carbon nanostructures and also to propose a mechanism for the formation of these groups (Chapter III). The functionalized nanotubes and nanofibers have been used as supports for heterogeneous catalysis. The hydrogenation of p-halonitrobenzene was used as model reaction to compare the catalytic performances of ruthenium supported on MWCNTs or CNFs-H catalysts. The influence of experimental parameters such as temperature, nature of the substrate and prior heat treatment (activation) of the catalyst on the catalytic activity and selectivity is presented. The catalytic performances have been correlated to the structure of the catalyst as determined from TEM, TPD, TPR and PZC analysis (Chapter IV). The carbon nanostructures produced have also been used as reinforcement fillers for hydroxyapatite-nanotube composites. We have studied in particular, the germination of octacalcium phosphate crystals under conditions of constant solution composition on the surface of the composite (Chapter V)
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White, Ashley Ann. "Production and characterisation of hydroxyapatite/multi-walled carbon nanotube composites." Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/224760.

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Hydroxyapatite (HA) is a biologically active ceramic that is used in surgery to replace bone. While HA promotes bone growth along its surface, its mechanical properties are not sufficient for major load-bearing medical devices. Carbon nanotubes (CNTs), as one of the strongest and stiffest materials available, have the potential to strengthen and toughen HA, thus expanding the range of clinical uses for the material. Furthermore, studies have suggested that the nanotubes themselves possess some bioactive properties. This work sought to develop and characterise HA-CNT composites in four main areas: 1) production and characterisation of green materials, 2) investigation of appropriate sintering atmospheres, 3) evaluation of mechanical properties, and 4) assessment of biological response to in vitro cell culture. HA was synthesised by a precipitation reaction between Ca(OH)2 and H3PO4, and multi-walled CNTs were produced by chemical vapour deposition. Composites were produced by adding the CNTs to the Ca(OH)2 solution as the HA was precipitating. Both as-made (nfCNTs) and acid-treated CNTs (fCNTs) were used to make composites with loadings of 0.5-5 wt.% CNTs. The resulting slurry was shear mixed and then processed to make a powder. The powder was then uniaxially pressed into tablets of ~45% theoretical density. Characterisation of the green material with XRD and FTIR found that the primary phase was HA which was well hydroxylated. The powder particles were found to have a bimodal size distribution, and all materials had similar surface areas, as determined by BET. Composites made with fCNTs were found to have a better dispersion of CNTs in the HA matrix and better interaction between the HA and CNTs compared with nfCNT composites. CNTs oxidise at the high temperatures needed to sinter HA, yet water is necessary to prevent dehydroxylation and decomposition of the HA. Using 5 wt.% fCNT composite, fourteen sintering atmospheres were investigated to determine their effect on phase purity, hydroxylation, sintered density, and remaining CNT content after sintering. An atmosphere of CO + H2 bubbled through ice water resulted in optimal properties. Additionally, it was found that increasing the gas flow rate and the number of samples sintered in one batch increased CNT retention. However, this came at the expense of the density of the sintered samples, as composites with a higher CNT content were more porous. To optimise the composite microstructure for mechanical studies, six different sintering time/temperature profiles were examined to determine their effect on density (balanced with CNT retention) and grain size. HA and both nfCNT and fCNT composites with CNT loadings of 0.5, 1, 2 and 5 wt.% were produced using the optimised atmosphere and profile, and then tested to determine tensile strength (using diametral compression) and hardness, and to look for evidence of toughening. It was found that CNTs had little reinforcing effect; instead, mechanical behaviour results were mainly attributed to differences in porosity, due at least in part to the CNTs' presence. The in vitro cellular response to the materials was examined by culturing human osteoblast-like cells on HA and nfCNT (0.88 wt.%) and fCNT (3.3 wt.%) composites for 12 days. Cells were found to attach and grow well on HA and the nfCNT composite, with slightly enhanced response on the composite. The fCNT composite, on the other hand, showed a decrease in cell viability between days 1 and 12. These results were mainly attributed to the effects of a lower local pH due to remnant acid on the fCNTs and differences in material characteristics, such as CNT loading and surface roughness. This systematic study of the production and properties of HA-CNT composites has resulted in improved understanding of the production and processing of these materials and the effects of a wide range of sintering atmospheres on their characteristics. Additionally, it has yielded interesting preliminary results of their mechanical reinforcement potential and biological behaviour.
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Lahiri, Debrupa. "Hydroxyapatite-Nanotube Composites and Coatings for Orthopedic Applications." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/444.

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Hydroxyapatite (HA) has received wide attention in orthopedics, due to its biocompatibility and osseointegration ability. Despite these advantages, the brittle nature and low fracture toughness of HA often results in rapid wear and premature fracture of implant. Hence, there is a need to improve the fracture toughness and wear resistance of HA without compromising its biocompatibility. The aim of the current research is to explore the potential of nanotubes as reinforcement to HA for orthopedic implants. HA- 4 wt.% carbon nanotube (CNT) composites and coatings are synthesized by spark plasma sintering and plasma spraying respectively, and investigated for their mechanical, tribological and biological behavior. CNT reinforcement improves the fracture toughness (>90%) and wear resistance (>66%) of HA for coating and free standing composites. CNTs have demonstrated a positive influence on the proliferation, differentiation and matrix mineralization activities of osteoblasts, during in-vitro biocompatibility studies. In-vivo exposure of HA-CNT coated titanium implant in animal model (rat) shows excellent histocompatibility and neobone integration on the implant surface. The improved osseointegration due to presence of CNTs in HA is quantified by the adhesion strength measurement of single osteoblast using nano-scratch technique. Considering the ongoing debate about cytotoxicity of CNTs in the literature, the present study also suggests boron nitride nanotube (BNNT) as an alternative reinforcement. BNNT with the similar elastic modulus and strength as CNT, were added to HA. The resulting composite having 4 wt.% BNNTs improved the fracture toughness (~85%) and wear resistance (~75%) of HA in the similar range as HA-CNT composites. BNNTs were found to be non-cytotoxic for osteoblasts and macrophages. In-vitro evaluation shows positive role of BNNT in osteoblast proliferation and viability. Apatite formability of BNNT surface in ~4 days establishes its osseointegration ability.
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Deshpande, Himani D. "Bioactive polycaprolactone/carbon nanofiber scaffolds for bone tissue regeneration." Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2009r/deshpande.pdf.

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Wu, Yung-Lin, and 吳勇霖. "Research of the electrolytic deposited Hydroxyapatite/Carbon nanotube composite coating." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/39279838338662973872.

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碩士
國立交通大學
機械工程系所
93
In this research, Hydroxyapatite/Carbon nanotube composite coating were deposited on titanium alloy by electrolytic method. CNT coating was processed by immersing the titanium alloy plate as electrode in carbon nanotube suspension and then the titanium alloy electrode was placed in a mixing solution of Ca(NO3)2.H2O and NH4H2PO4 to form the HAp layer. After heat-treatment, the samples were characterized by SEM、XRD、FTIR、Micro hardness test、Adhesion test and cell culture were followed. The hardness of the HAp layer was found increased when a CNT layer was added between titanium plate and HAp layer but the adhesion strength of HAp coatings on titanium alloys were decreased when the intermediate CNT coating were existed. In addition, the CNT coating affect the phase transformation after heat-treatment of the HAp. SEM observation of cell culture revealed the better extension of osteoblast-like cell on CNT coated specimens then on those uncoated. The result indicate that coating of CNT intermediate layer promote better biocompatibility.
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鄒沛雯. "On the growth of hydroxyapatite on polyurethane / carbon nanotubes composite." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/34281210496907674795.

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Ravikumar, K. "Development of Multifunctional Biomaterials and Probing the Electric Field Stimulated Cell Functionality on Conducting Substrates : Experimental and Theoretical Studies." Thesis, 2015. http://hdl.handle.net/2005/3197.

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Materials with appropriate combinations of multifunctional properties (strength, toughness, electrical conductivity and piezoelectricity) together with desired biocompatibility are promising candidates for biomedical applications. Apart from these material properties, recent studies have shown the efficacy of electric field in altering cell functionality in order to elicit various cell responses, like proliferation, differentiation, apoptosis (programmed cell death) on conducting substrates in vitro. In the above perspective, the current work demonstrates how CaTiO3 (CT) addition to Hydroxyapatite (HA) can be utilised to obtain an attractive combination of long crack fracture toughness (up to 1.7 MPa.m1/2 measured using single edge V-notch beam technique) and a flexural strength of 155 MPa in addition to moderate electrical conductivity. The enhancement of fracture toughness in HA-CT composites has been explained based on the extensive characterization of twinned microstructure in CT along with the use of theoretical models for predicting the enhancement of toughening through crack tip tilt and twist mechanisms. Subsequent in vitro studies on HA-CT composites with human Mesenchymal Stem cells (hMSCs) in the presence of electric field has shown enhanced differentiation towards bone like cells (osteogenic lineage) as evaluated by ALP activity, Collagen content and gene expression analyses through Polymerase Chain Reaction (PCR) at the end of two weeks. he extracellular matrix mineralization analysis at the end of 4 weeks of hMSC culture further substantiated the efficacy of electric field as a biochemical cue that can influence the stem cell fate processes on conducting substrates. The electric field stimulation strategy was also implemented in in vitro studies with C2C12 mouse myoblast (muscle) cells on elastically compliant poly(vinylidene difluoride) (PVDF)-multiwall carbon nanotube (MWNT) composite substrates. PVDF is a piezoelectric polymer and the addition of MWNTs makes the composite electrically conducting. Upon, electric field stimulation of C2C12 mouse myoblast cells on these composites, has been observed that in a narrow window of electric field parameters, the cell viability was enhanced along with excellent cell alignment and cell-cell contact indicating a potential application of PVDF-based materials in the muscle cell regeneration. In an effort to rationalise such experimental observations, a theoretical model is proposed to explain the development of bioelectric stress field induced cell shape stability and deformation. A single cell is modelled as a double layered membrane separating the culture medium and the cytoplasm with different dielectric properties. This system is linearized by invoking Debye-Huckel approximation of the Poisson-Boltzmann equation. With appropriate boundary conditions, the system is solved to obtain intracellular and extracellular Maxwell stress as a function of multiple parameters like cell size, intracellular and extracellular permittivity and electric field strength. Based on the stresses, we predict shape changes of cell membrane by approximating the deformation amplitude under the influence of electric field. Apart from this, the shear stress on the membrane has been used to determine the critical electric field required to induce membrane breakdown. The analysis is conducted for a cell in suspension/on a conducting substrate and on an insulating substrate to illustrate the effect of substrate properties on cell response under the influence of external electric field.
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Book chapters on the topic "Hydroxyapatite/carbon composite"

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White, Ashley A., Serena M. Best, and Ian A. Kinloch. "Hydroxyapatite-Carbon Nanotube Composites for Biomedical Applications: A Review." In Progress in Nanotechnology, 57–69. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9780470588260.ch9.

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Zhu, Guang Yan, Jian Feng Huang, Li Yun Cao, Min Zhou, and Jian Peng Wu. "Preparation of Hydroxyapatite Coatings on Carbon/Carbon Composites by a Hydrothermal Electrodeposition Process." In High-Performance Ceramics V, 1238–40. Stafa: Trans Tech Publications Ltd., 2008. http://dx.doi.org/10.4028/0-87849-473-1.1238.

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Ling, Siu Jin, Li Mu Sen, and Lu Yu Peng. "The Bond Strength and Fracture Behaviors of Hydroxyapatite Coatings on Carbon/Carbon Composites." In Key Engineering Materials, 233–36. Stafa: Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-978-4.233.

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Parwez, Khalid, Arun A. Bhagwath, Asif Zawed, Bhagwan Rekadwad, and Suman V. Budihal. "Carbon Nanotubes Integrated Hydroxyapatite Nano-Composite for Orthopaedic and Tissue Engineering Applications." In Sol Gel and other Fabrication Methods of Advanced Carbon Materials [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97428.

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The reassessment of the literature stipulates that an increasing amount of research in exploring the Hydroxyapatite Carbon Nanotubes (HA-CNT) system for orthopedic application. Chemical precipitation, CNT functionalization, and spray drying are the routinely used methods for CNT dispersal in HA matrix for the application such as bone tissue engineering, nanostructured scaffolds, dental regeneration, myocardial regeneration, and skin regeneration. Although mechanical strength and biocompatibility is a substantial concern for the fabrication of structures. Developing composite and bioceramic scaffolding with different natural and synthetic biomaterials are the futuristic approach in the biomedical engineering field. The problems such as biocompatibility, biodegradability, and mechanical resistance can be solved by combining natural, and artificial biomaterials. The natural biomaterials, such as collagen, cellulose, chitosan, have a close resemblance to the natural extracellular matrix (ECM). These materials are biocompatible, biodegradable. The artificial biomaterials, such as Poly Vinyl Pyrrolidone (PVP), Poly Capro Lactone (PCL), Poly Ethylene Glycol (PEG), and Poly Lactic Acid (PLA) are also the material of choice for the fabrication of the composite materials. Additional effort is necessary to fabricate biocompatible composite scaffolding for tissue engineering. Moreover, vascularization, differentiation, cellular proliferation, and cells to scaffold interaction are the foremost challenges in the area of tissue engineering that remains to overcome.
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Conference papers on the topic "Hydroxyapatite/carbon composite"

1

Rezvanova, A. E., M. S. Barabashko, M. V. Tkachenko, A. N. Ponomarev, A. A. Neiman, and A. A. Belosludtseva. "Experimental measurements and calculation of fracture toughness coefficient of a hydroxyapatite composite with small concentrations of additives of multi-walled carbon nanotubes." In PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON PHYSICAL MESOMECHANICS. MATERIALS WITH MULTILEVEL HIERARCHICAL STRUCTURE AND INTELLIGENT MANUFACTURING TECHNOLOGY. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0034534.

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2

Narayan, R. J. "Novel Nanostructural Biomaterial Composites." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-39374.

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Hydrogen-free diamondlike carbon (DLC), with hardness values close to that of diamond, possess many desirable biocompatible properties for a variety of biomedical applications. The DLC coatings can be applied to joints prostheses, heart valves, and other medical devices. Unfortunately, hydrogen-free DLC coatings have a large compressive stresses which result in poor adhesion and wear characteristics. In this paper, we present results on silver doping of DLC to alleviate internal stresses as well as create DLC-Ag nanocomposites where Ag is in the form of nanoparticles. The Ag nanoparticles are expected to impart antimicrobial properties by providing sources of electrons. In the second part of the paper, we have created DLC and nanotube composites where nanotubes grow normal to the surface. This novel architecture not only alleviates internal stresses, but DLC + Nanotube composites have enhanced hardness and unique antimicrobial properties. Finally, we discuss novel multilayer DLC and hydroxyapatite (HA) composite where HA and DLC films are deposited sequentially at room temperature. The HA films with composites close to that of bone is considered very desirable for biocompatibility and integration with base structures. We discuss novel processing, characterization, hardness and bioeompatible properties of all these composites in detail.
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3

Tanaka, Masa-aki. "Mechanical Properties of Carbon Nanotubes / Hydroxyapatite Composites Prepared by Spark Plasma Sintering." In FLOW DYNAMICS: The Second International Conference on Flow Dynamics. AIP, 2006. http://dx.doi.org/10.1063/1.2204536.

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