Relevant bibliographies by topics / Huntington's disease Magnetic resonance imaging

Academic literature on the topic 'Huntington's disease Magnetic resonance imaging'

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Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Huntington's disease Magnetic resonance imaging"

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Sethi, Kapil D. "Magnetic resonance imaging in huntington's disease." Movement Disorders 6, no. 2 (1991): 186. http://dx.doi.org/10.1002/mds.870060223.

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Singh, Paramdeep, and Rupinderjeet Kaur. "Magnetic resonance imaging findings in case of Huntington's disease." Journal of Clinical Sciences 17, no. 1 (2020): 9. http://dx.doi.org/10.4103/jcls.jcls_46_19.

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Klöppel, S., S. M. Henley, N. Z. Hobbs, R. C. Wolf, J. Kassubek, S. J. Tabrizi, and R. S. J. Frackowiak. "Magnetic resonance imaging of Huntington's disease: preparing for clinical trials." Neuroscience 164, no. 1 (November 2009): 205–19. http://dx.doi.org/10.1016/j.neuroscience.2009.01.045.

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Wolf, Robert Christian, Fabio Sambataro, Nenad Vasic, Nadine Donata Wolf, Philipp Arthur Thomann, G. Bernhard Landwehrmeyer, and Michael Orth. "Longitudinal functional magnetic resonance imaging of cognition in preclinical Huntington's disease." Experimental Neurology 231, no. 2 (October 2011): 214–22. http://dx.doi.org/10.1016/j.expneurol.2011.06.011.

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Domínguez, Juan F., Julie C. Stout, Govinda Poudel, Andrew Churchyard, Phyllis Chua, Gary F. Egan, and Nellie Georgiou-Karistianis. "Multimodal imaging biomarkers in premanifest and early Huntington's disease: 30-month IMAGE-HD data." British Journal of Psychiatry 208, no. 6 (June 2016): 571–78. http://dx.doi.org/10.1192/bjp.bp.114.156588.

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BackgroundThe discovery of potential disease-modifying therapies in a neurodegenerative condition like Huntington's disease depends on the availability of sensitive biomarkers that reflect decline across disease stages and that are functionally and clinically relevant.AimsTo quantify macrostructural and microstructural changes in participants with premanifest and symptomatic Huntington's disease over 30 months, and to establish their functional and clinical relevance.MethodMultimodal magnetic resonance imaging study measuring changes in macrostructural (volume) and microstructural (diffusivity) measures in 40 patients with premanifest Huntington's disease, 36 patients with symptomatic Huntington's disease and 36 healthy control participants over three testing sessions spanning 30 months.ResultsRelative to controls, there was greater longitudinal atrophy in participants with symptomatic Huntington's disease in whole brain, grey matter, caudate and putamen, as well as increased caudate fractional anisotropy; caudate volume loss was the only measure to differ between premanifest Huntington's disease and control groups. Changes in caudate volume and fractional anisotropy correlated with each other and neurocognitive decline; caudate volume loss also correlated with clinical and disease severity.ConclusionsCaudate neurodegeneration, especially atrophy, may be the most suitable candidate surrogate biomarker for consideration in the development of upcoming clinical trials.
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Bohanna, India, Nellie Georgiou-Karistianis, Anthony J. Hannan, and Gary F. Egan. "Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease." Brain Research Reviews 58, no. 1 (June 2008): 209–25. http://dx.doi.org/10.1016/j.brainresrev.2008.04.001.

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Starkstein, S. E., J. Brandt, F. Bylsma, C. Peyser, M. Folstein, and S. E. Folstein. "Neuropsychological correlates of brain atrophy in Huntington's disease: a magnetic resonance imaging study." Neuroradiology 34, no. 6 (1992): 487–89. http://dx.doi.org/10.1007/bf00598956.

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Aylward, Elizabeth H. "Magnetic resonance imaging striatal volumes: A biomarker for clinical trials in Huntington's disease." Movement Disorders 29, no. 11 (August 27, 2014): 1429–33. http://dx.doi.org/10.1002/mds.26013.

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Wolf, Robert C., Georg Grön, Fabio Sambataro, Nenad Vasic, Nadine D. Wolf, Philipp A. Thomann, Carsten Saft, G. Bernhard Landwehrmeyer, and Michael Orth. "Magnetic resonance perfusion imaging of resting-state cerebral blood flow in preclinical Huntington's disease." Journal of Cerebral Blood Flow & Metabolism 31, no. 9 (May 11, 2011): 1908–18. http://dx.doi.org/10.1038/jcbfm.2011.60.

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Magnetic resonance imaging (MRI) of the brain could be a powerful tool for discovering early biomarkers in clinically presymptomatic carriers of the Huntington's disease gene mutation (preHD). The aim of this study was to investigate the sensitivity of resting-state perfusion MRI in preHD and to identify neural changes, which could serve as biomarkers for future clinical trials. Differences in regional cerebral blood flow (rCBF) in 18 preHD and 18 controls were assessed with a novel MRI method based on perfusion images obtained with continuous arterial spin labeling. High-resolution structural data were collected to test for changes of brain volume. Compared with controls, preHD individuals showed decreased rCBF in medial and lateral prefrontal regions and increased rCBF in the precuneus. PreHD near to symptom onset additionally showed decreased rCBF in the putamen and increased rCBF in the hippocampus. Network analyses revealed an abnormal lateral prefrontal pattern in preHD far and near to motor onset. These data suggest early changes of frontostriatal baseline perfusion in preHD independent of substantial reductions of gray matter volume. This study also shows the feasibility of detecting neural changes in preHD with a robust MRI technique that would be suitable for longitudinal multisite application.
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Harris, Gordon J., Godfrey D. Pearlson, Carol E. Peyser, Elizabeth H. Aylward, Joy Roberts, Patrick E. Barta, Gary A. Chase, and Susan E. Folstein. "Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington's disease." Annals of Neurology 31, no. 1 (January 1992): 69–75. http://dx.doi.org/10.1002/ana.410310113.

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Dissertations / Theses on the topic "Huntington's disease Magnetic resonance imaging"

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Richards, Jennifer Margaret Jane. "Magnetic resonance imaging in cardiovascular disease." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/8079.

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Background Superparamagnetic particles of iron oxide (SPIO) are part of a novel and exciting class of ‘smart’ magnetic resonance imaging (MRI) contrast agents that are taken up by inflammatory cells. Ultrasmall SPIO (USPIO; ~30 nm diameter) can be used to assess cellular tissue inflammation and SPIO (80-150 nm) have the potential to be used to label cells ex vivo for in vivo cell tracking studies. Objectives The aims of the thesis were therefore (i) to develop and validate quantitative MRI methodology for assessing SPIO uptake within tissues, (ii) to demonstrate USPIO accumulation within the aortic wall and its implications in patients with abdominal aortic aneurysms (AAA), and (iii) to develop and apply a Good Manufacturing Practice (GMP) compliant method of SPIO cell labelling in healthy volunteers. Methods Patients with asymptomatic AAA >4.0 cm in diameter were recruited. Imaging sequences were optimised in eight patients using a 3 tesla MRI scanner. Data were analysed using the decay constant for multi echo T2* weighted (T2*W) sequences (T2*) or its inverse (R2*) and the repeatability of these measurements was established. A further twenty-nine patients underwent MRI scanning before and 24- 36 hours after administration of USPIO. T2 and multi echo T2*W sequences were performed and ultrasound-based growth rate data were collected. Operative aortic wall tissue samples were obtained from patients undergoing open surgical aneurysm repair. A GMP compliant protocol was developed for labelling cells with SPIO for clinical cell tracking studies. The effects of SPIO-labelling on cell viability and function were assessed in vitro. A phased-dosing protocol was used to establish the safety of intravenous administration of SPIO-labelled cells in healthy volunteers. The feasibility of imaging cells at a target site in vivo following local or systemic administration was assessed. Tracking of SPIO-labelled cells to a target site was investigated by inducing an iatrogenic inflammatory focus in the skin of the anterior thigh of healthy volunteers, following which autologous SPIO-labelled cells were administered and their accumulation was assessed using MRI scanning and histology of skin biopsies. Results Robust and semi-quantitative data acquisition and image analysis methodology was developed for the assessment of SPIO accumulation in tissues. In patients with AAA, histological analysis of aortic wall tissue samples confirmed USPIO accumulation in areas of cellular inflammation. USPIO-enhanced MRI detected aortic wall inflammation and mural USPIO uptake was associated with a 3-fold higher aneurysm expansion rate. Human mononuclear cells were labelled with SPIO under GMP compliant conditions without affecting cell viability or function. Both local and intravenous administration of SPIO-labelled cells was safe and cells were detectable in vitro and in vivo using a clinical MRI scanner. SPIO-labelled cells tracked to a focal iatrogenic inflammatory focus following intravenous administration in humans and were detectable on MRI scanning and histological examination of skin biopsies. Conclusions SPIO contrast agents have an extensive range of potential clinical applications. USPIO uptake in the wall of AAA appears to identify cellular inflammation and predict accelerated aneurysm expansion. This is therefore a promising investigative tool for stratifying the risk of disease progression in patients with AAA, and may also be considered as a biomarker for response to novel pharmacological agents. The ability to label cells for non-invasive cell tracking studies would facilitate the further development of novel cell-based therapies and would enable assessment of dynamic inflammatory processes through inflammatory cell tracking.
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Manners, David Neil. "Magnetic resonance imaging and magnetic resonance spectroscopy of skeletal muscle." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269250.

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Fox, Charles Nicholas Ilya. "Magnetic resonance imaging of atrophy in Alzheimer's disease." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400512.

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Hochbergs, Peter. "Magnetic resonance imaging in Legg-Calvé-Perthes disease." Lund : Depts. of Diagnostic Radiology and Orthopedics, University Hospital, 1998. http://catalog.hathitrust.org/api/volumes/oclc/40178137.html.

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Watson, Paul J. "A magnetic resonance imaging study of degenerative joint disease." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338026.

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U-King-Im, Jean Marie Kim Sin. "Evaluation of carotid atherosclerotic disease by Magnetic Resonance Imaging." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612046.

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Shereen, Ahmed D. "Diffusion Tensor Magnetic Resonance Imaging Applications to Neurological Disease." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1300393032.

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Shalabi, Adel. "Magnetic resonance imaging in chronic achilles tendinopathy /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-811-4/.

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Cheng, Adrfian Seng Hung. "Functional assessment of coronary artery disease using magnetic resonance imaging." Thesis, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542949.

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Moore, Elizabeth Anne. "Quantitative magnetic resonance imaging in arthritis and diabetic microvascular disease." Thesis, University of Exeter, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278798.

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Books on the topic "Huntington's disease Magnetic resonance imaging"

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Magnetic resonance imaging of congenital heart disease. London: Springer, 2012.

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Syed, Mushabbar A., and Raad H. Mohiaddin, eds. Magnetic Resonance Imaging of Congenital Heart Disease. London: Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-4267-6.

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van der Wall, Ernst E., and Albert de Roos, eds. Magnetic Resonance Imaging in Coronary Artery Disease. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3772-0.

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Magnetic resonance imaging of CNS disease: A teaching file. St. Louis: Mosby, 2002.

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Yock, Douglas H. Magnetic resonance imaging of CNS disease: A teaching file. St. Louis: Mosby, 1995.

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Moseley, I. F. Diagnostic imaging in neurological disease. Edinburgh: Churchill Livingstone, 1986.

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Moseley, I. F. Diagnostic imaging in neurological disease. Edinburgh: Churchill Livingstone, 1986.

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Paul, Tofts, ed. Quantitative MRI of the brain: Measuring changes caused by disease. Chichester, West Sussex: Wiley, 2003.

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B, Higgins Charles, Ingwall Joanne S, and Pohost Gerald M, eds. Current and future applications of magnetic resonance in cardiovascular disease. Armonk, NY: Futura Pub. Co., 1998.

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Atlas of cardiovascular magnetic resonance imaging: An imaging companion to Braunwald's heart disease. Philadelphia, PA: Saunders Elsevier, 2010.

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Book chapters on the topic "Huntington's disease Magnetic resonance imaging"

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Gregory, Sarah, Rachael I. Scahill, Geraint Rees, and Sarah Tabrizi. "Magnetic Resonance Imaging in Huntington’s Disease." In Methods in Molecular Biology, 303–28. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7825-0_16.

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Underwood, S. R., and R. H. Mohiaddin. "Magnetic Resonance Imaging." In Epidemiology of Peripheral Vascular Disease, 55–66. London: Springer London, 1991. http://dx.doi.org/10.1007/978-1-4471-1889-3_5.

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Baker, Edward J. "Magnetic resonance imaging." In Congenital heart disease in adolescents and adults, 79–89. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-015-8082-3_5.

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Bittersohl, Bernd, and Christoph Zilkens. "Labral Disease." In Hip Magnetic Resonance Imaging, 149–60. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1668-5_11.

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Fogel, Mark A. "Magnetic Resonance Imaging." In Ventricular Function and Blood Flow in Congenital Heart Disease, 124–46. Malden, Massachusetts, USA: Blackwell Publishing, 2007. http://dx.doi.org/10.1002/9780470994849.ch8.

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Ariyarajah, Vignendra, and Raymond Y. Kwong. "Valvular Heart Disease." In Cardiovascular Magnetic Resonance Imaging, 491–503. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-306-6_23.

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Wald, Rachel M., and Andrew J. Powell. "Congenital Heart Disease." In Cardiovascular Magnetic Resonance Imaging, 537–65. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-306-6_25.

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Heeswijk, Ruud B. van, Christine Gonzales, and Juerg Schwitter. "Chapter 7 Cardiac Disease." In Fluorine Magnetic Resonance Imaging, 191–220. Pan Stanford Publishing Pte. Ltd. Penthouse Level, Suntec Tower 3, 8 Temasek Boulevard, Singapore 038988: Pan Stanford Publishing, 2016. http://dx.doi.org/10.1201/9781315364605-8.

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Nezafat, Reza, Susie N. Hong, Peng Hu, Mehdi Hedjazi Moghari, and Warren J. Manning. "Noninvasive Imaging for Coronary Artery Disease." In Magnetic Resonance Angiography, 337–49. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-1686-0_24.

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Al-Mallah, Mouaz, and Raymond Y. Kwong. "Assessing Pericardial Disease by CMR." In Cardiovascular Magnetic Resonance Imaging, 467–89. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-306-6_22.

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Conference papers on the topic "Huntington's disease Magnetic resonance imaging"

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Guerreiro, Carla, Leonor Correia Guedes, Madalena Rosário, Giulia Galati, David Berhanu, Rita Moiron Simões, Joaquim J. Ferreira, and Sofia Reimão. "E09 Magnetic resonance imaging visual analysis of neuromelanin and nigrosome-1 for the assessment of striatonigral disfunction in huntington’s disease." In EHDN Abstracts 2021. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/jnnp-2021-ehdn.43.

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Hellem, Marie N., Tua Vinther-Jensen, Christian Hansen, Lasse Anderberg, Esben Budtz-Jørgensen, Lena E. Hjermind, Vibeke A. Larsen, Ian Law, and Jørgen E. Nielsen. "E09 Hybrid brain positron emision tomography – magnetic resonance imaging using flurodeoxyglucose (FDG – PET/MRI) in premanifest huntingtons disease gene-expansion." In EHDN 2018 Plenary Meeting, Vienna, Austria, Programme and Abstracts. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/jnnp-2018-ehdn.103.

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Carvalho, Nichollas de Lorenzi. "Huntington’s disease in a young patient: case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.027.

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Context: Huntington’s disease (HD) is characterized by a progressive, autosomal neurodegenerative disease dominant, characterized by motor, psychiatric manifestations and cognitive decline due to a genetic alteration with 36 to 121 CAG repetitions on chromosome 4, which leads to the mutation of the huntingtin protein and its nuclear accumulation with formations of cytoplasmic inclusions of the affected neurons. It being more common between the third and fifth decade of life. The aim of this study was to report the case of a young patient with HD. Case report: Female patient, 6 years old. Mother reports seizures for 3 years, associated with abnormal lower limb posture, as well as rapid shock-like limbs, lasting a few minutes, eye upwards, loss of consciousness, difficulties in swallowing and loss of ability to walk at 5 years of age. Mother reports family history of involuntary motor shocks. The neurological examination showed a vigil, global epasticity; Global hyperreflexia; Bilateral aquilean inexhaustible clonus; Plantar skin reflex in bilateral extension. Upon examination of the cranial nerves, presented isochoric and photoreactive pupils, preserved extrinsic ocular motricity, symmetrical face, tongue and palate symmetrical, trophism and neurovegetative functions without changes. Magnetic resonance imaging was requested, showing atrophy of the caudate nucleus, and research for Huntington’s disease, confirming the diagnosis. Conclusions: the reported case brings to light the rarity of the disease manifestation in younger patients and supposed correlation with family history, corroborating with the evidence of the factor disease as the main risk factor for the development of HD.
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Cai, Zifan, Qian Di, Kewei Chen, Eric M. Reiman, Liang Wang, Kuncheng Li, Jie Tang, Li Yao, and Xiaojie Zhao. "Automated diagnosis and prediction of Alzheimer disease using magnetic resonance image." In Medical Imaging, edited by Maryellen L. Giger and Nico Karssemeijer. SPIE, 2007. http://dx.doi.org/10.1117/12.708376.

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Adams Bornemeier, Renee, Kenneth E. Fellows, Mark A. Fogel, and Paul M. Weinberg. "Anatomical delineation of congenital heart disease using 3D magnetic resonance imaging." In Medical Imaging 1994, edited by Eric A. Hoffman and Raj S. Acharya. SPIE, 1994. http://dx.doi.org/10.1117/12.174392.

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Grunz, J. P., A. Kunz, C. Gietzen, H. Huflage, N. Hesse, and R. Schmitt. "Staging of Preiser's Disease Using Contrast-Enhanced Magnetic Resonance Imaging." In 28th Annual Scientific Meeting of the European Society of Musculoskeletal Radiology (ESSR), Virtual Edition, June 2021. Thieme Medical Publishers, Inc., 2021. http://dx.doi.org/10.1055/s-0041-1731556.

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Ziselman, Yaniv, Faten Hajali Shinnawi, Mary-Louise Greer, Gili Focht, Dan Turner, and Moti Freiman. "Gadolinium-Free Crohn’s Disease Assessment from Magnetic Resonance Enterography Data." In 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI). IEEE, 2022. http://dx.doi.org/10.1109/isbi52829.2022.9761473.

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Ziselman, Yaniv, Faten Hajali Shinnawi, Mary-Louise Greer, Gili Focht, Dan Turner, and Moti Freiman. "Gadolinium-Free Crohn’s Disease Assessment from Magnetic Resonance Enterography Data." In 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI). IEEE, 2022. http://dx.doi.org/10.1109/isbi52829.2022.9761473.

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Liu, Xi, Yu Wang, Changyang Fu, Hongbing Xiao, and Suxia Xing. "Aided Diagnosis of Alzheimer's Disease Based on Structural Magnetic Resonance Imaging." In 2019 6th International Conference on Systems and Informatics (ICSAI). IEEE, 2019. http://dx.doi.org/10.1109/icsai48974.2019.9010118.

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Fogel, Mark A. "Evaluation of ventricular geometry and performance in congenital heart disease utilizing magnetic resonance imaging." In Medical Imaging 1994, edited by Eric A. Hoffman and Raj S. Acharya. SPIE, 1994. http://dx.doi.org/10.1117/12.174393.

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Reports on the topic "Huntington's disease Magnetic resonance imaging"

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Wu, Xin. The efficacy and safety of anti-CD20 antibody treatments in relapsing multiple sclerosis: a systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0075.

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Review question / Objective: The objectives of this systematic review were to evaluate the efficacy and safety of the three existing anti-CD20 antibodies for the treatment of relapsing multiple sclerosis and to aid clinicians in choosing medications. Eligibility criteria: We set the inclusion criteria as follows: (1) study type: RCT; (2) language restriction: only available in English; (3) participants: patients ≥18 years of age diagnosed with relapsing MS, whether with a relapsing–remitting course or a secondary progressive course; (4) intervention: anti-CD20 antibody treatments including ocrelizumab, ofatumumab, rituximab, and corresponding control including placebo and active treatments; (5) outcomes: clinical outcomes including annualized rate of relapse (ARR), the number of patients free of relapse, and the number of patients with confirmed disease progression (CDP); magnetic resonance imaging(MRI) outcomes including gadolinium-enhancing lesion change in T1, change in the volume of lesions on T2, the number of patients with no new or newly enlarged lesions in T2 and the brain volume change (BVC); safety outcomes including adverse events (AEs) and serious adverse events (SAEs). Included RCTs were not requested to supply all the outcomes mentioned above. We set the exclusion criteria as follows: (1) study type: retrospective studies, cohort studies, case reviews and case reports; (2) patients diagnosed with primary progressive MS.
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