Journal articles on the topic 'Human telomeric'
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Tommerup, H., A. Dousmanis, and T. de Lange. "Unusual chromatin in human telomeres." Molecular and Cellular Biology 14, no. 9 (September 1994): 5777–85. http://dx.doi.org/10.1128/mcb.14.9.5777-5785.1994.
Full textTommerup, H., A. Dousmanis, and T. de Lange. "Unusual chromatin in human telomeres." Molecular and Cellular Biology 14, no. 9 (September 1994): 5777–85. http://dx.doi.org/10.1128/mcb.14.9.5777.
Full textCook, Brandoch D., Jasmin N. Dynek, William Chang, Grigoriy Shostak, and Susan Smith. "Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres." Molecular and Cellular Biology 22, no. 1 (January 1, 2002): 332–42. http://dx.doi.org/10.1128/mcb.22.1.332-342.2002.
Full textMattern, Karin A., Susan J. J. Swiggers, Alex L. Nigg, Bob Löwenberg, Adriaan B. Houtsmuller, and J. Mark J. M. Zijlmans. "Dynamics of Protein Binding to Telomeres in Living Cells: Implications for Telomere Structure and Function." Molecular and Cellular Biology 24, no. 12 (June 15, 2004): 5587–94. http://dx.doi.org/10.1128/mcb.24.12.5587-5594.2004.
Full textBrault, Marie Eve, and Chantal Autexier. "Telomeric recombination induced by dysfunctional telomeres." Molecular Biology of the Cell 22, no. 2 (January 15, 2011): 179–88. http://dx.doi.org/10.1091/mbc.e10-02-0173.
Full textFernandes, Stina George, Rebecca Dsouza, Gouri Pandya, Anuradha Kirtonia, Vinay Tergaonkar, Sook Y. Lee, Manoj Garg, and Ekta Khattar. "Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential." Cancers 12, no. 7 (July 14, 2020): 1901. http://dx.doi.org/10.3390/cancers12071901.
Full textLin, Chih-Yi Gabriela, Anna Christina Näger, Thomas Lunardi, Aleksandra Vančevska, Gérald Lossaint, and Joachim Lingner. "The human telomeric proteome during telomere replication." Nucleic Acids Research 49, no. 21 (November 8, 2021): 12119–35. http://dx.doi.org/10.1093/nar/gkab1015.
Full textBoccardi, Virginia, Luigi Cari, Giuseppe Nocentini, Carlo Riccardi, Roberta Cecchetti, Carmelinda Ruggiero, Beatrice Arosio, Giuseppe Paolisso, Utz Herbig, and Patrizia Mecocci. "Telomeres Increasingly Develop Aberrant Structures in Aging Humans." Journals of Gerontology: Series A 75, no. 2 (November 2, 2018): 230–35. http://dx.doi.org/10.1093/gerona/gly257.
Full textGroff-Vindman, Cindy, Anthony J. Cesare, Shobhana Natarajan, Jack D. Griffith, and Michael J. McEachern. "Recombination at Long Mutant Telomeres Produces Tiny Single- and Double-Stranded Telomeric Circles." Molecular and Cellular Biology 25, no. 11 (June 1, 2005): 4406–12. http://dx.doi.org/10.1128/mcb.25.11.4406-4412.2005.
Full textCalado, Rodrigo T., Solomon A. Graf, and Neal S. Young. "Telomeric Recombination in Lymphocytes Implicates ALT, an Alternative Mechanism for Telomere Length Maintenance, in Normal Human Hematopoietic Cells." Blood 110, no. 11 (November 16, 2007): 1332. http://dx.doi.org/10.1182/blood.v110.11.1332.1332.
Full textHsieh, Yi-Ching, Pei-Jung Tu, Ying-Yuan Lee, Chun-Chen Kuo, Yi-Chien Lin, Chi-Fang Wu, and Jing-Jer Lin. "The U3 small nucleolar ribonucleoprotein component Imp4p is a telomeric DNA-binding protein." Biochemical Journal 408, no. 3 (November 28, 2007): 387–93. http://dx.doi.org/10.1042/bj20070968.
Full textLi, Bibo, and Titia de Lange. "Rap1 Affects the Length and Heterogeneity of Human Telomeres." Molecular Biology of the Cell 14, no. 12 (December 2003): 5060–68. http://dx.doi.org/10.1091/mbc.e03-06-0403.
Full textCaslini, Corrado, James A. Connelly, Amparo Serna, Dominique Broccoli, and Jay L. Hess. "MLL Associates with Telomeres and Regulates Telomeric Repeat-Containing RNA Transcription." Molecular and Cellular Biology 29, no. 16 (June 15, 2009): 4519–26. http://dx.doi.org/10.1128/mcb.00195-09.
Full textMarchesini, M., R. Matocci, L. Tasselli, V. Cambiaghi, A. Orleth, L. Furia, C. Marinelli, et al. "PML is required for telomere stability in non-neoplastic human cells." Oncogene 35, no. 14 (June 29, 2015): 1811–21. http://dx.doi.org/10.1038/onc.2015.246.
Full textEsnault, Germain, Stefano Majocchi, Danielle Martinet, Nathalie Besuchet-Schmutz, Jacques S. Beckmann, and Nicolas Mermod. "Transcription Factor CTF1 Acts as a Chromatin Domain Boundary That Shields Human Telomeric Genes from Silencing." Molecular and Cellular Biology 29, no. 9 (March 9, 2009): 2409–18. http://dx.doi.org/10.1128/mcb.00779-08.
Full textYang, Qin, Yun-Ling Zheng, and Curtis C. Harris. "POT1 and TRF2 Cooperate To Maintain Telomeric Integrity." Molecular and Cellular Biology 25, no. 3 (February 1, 2005): 1070–80. http://dx.doi.org/10.1128/mcb.25.3.1070-1080.2005.
Full textWu, Guanhui, Luying Chen, Wenting Liu, and Danzhou Yang. "Molecular Recognition of the Hybrid-Type G-Quadruplexes in Human Telomeres." Molecules 24, no. 8 (April 22, 2019): 1578. http://dx.doi.org/10.3390/molecules24081578.
Full textVinayagamurthy, Soujanya, Akansha Ganguly, and Shantanu Chowdhury. "Extra-telomeric impact of telomeres: Emerging molecular connections in pluripotency or stemness." Journal of Biological Chemistry 295, no. 30 (May 22, 2020): 10245–54. http://dx.doi.org/10.1074/jbc.rev119.009710.
Full textSmogorzewska, Agata, Bas van Steensel, Alessandro Bianchi, Stefan Oelmann, Matthias R. Schaefer, Gisela Schnapp, and Titia de Lange. "Control of Human Telomere Length by TRF1 and TRF2." Molecular and Cellular Biology 20, no. 5 (March 1, 2000): 1659–68. http://dx.doi.org/10.1128/mcb.20.5.1659-1668.2000.
Full textHiga, Mitsunori, Yukihiro Matsuda, Jumpei Fujii, Nozomi Sugimoto, Kazumasa Yoshida, and Masatoshi Fujita. "TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress." Nucleic Acids Research 49, no. 21 (November 11, 2021): 12234–51. http://dx.doi.org/10.1093/nar/gkab1004.
Full textBritt-Compton, B., and D. M. Baird. "Intra-allelic mutation at human telomeres." Biochemical Society Transactions 34, no. 4 (July 21, 2006): 581–82. http://dx.doi.org/10.1042/bst0340581.
Full textGineitis, Arunas A., Irina A. Zalenskaya, Peter M. Yau, E. Morton Bradbury, and Andrei O. Zalensky. "Human Sperm Telomere–Binding Complex Involves Histone H2b and Secures Telomere Membrane Attachment." Journal of Cell Biology 151, no. 7 (December 25, 2000): 1591–98. http://dx.doi.org/10.1083/jcb.151.7.1591.
Full textAncelin, Katia, Michele Brunori, Serge Bauwens, Catherine-Elaine Koering, Christine Brun, Michelle Ricoul, Jean-Patrick Pommier, Laure Sabatier, and Eric Gilson. "Targeting Assay To Study the cis Functions of Human Telomeric Proteins: Evidence for Inhibition of Telomerase by TRF1 and for Activation of Telomere Degradation by TRF2." Molecular and Cellular Biology 22, no. 10 (May 15, 2002): 3474–87. http://dx.doi.org/10.1128/mcb.22.10.3474-3487.2002.
Full textHenderson, S., R. Allsopp, D. Spector, S. S. Wang, and C. Harley. "In situ analysis of changes in telomere size during replicative aging and cell transformation." Journal of Cell Biology 134, no. 1 (July 1, 1996): 1–12. http://dx.doi.org/10.1083/jcb.134.1.1.
Full textKelleher, Colleen, Isabel Kurth, and Joachim Lingner. "Human Protection of Telomeres 1 (POT1) Is a Negative Regulator of Telomerase Activity In Vitro." Molecular and Cellular Biology 25, no. 2 (January 15, 2005): 808–18. http://dx.doi.org/10.1128/mcb.25.2.808-818.2005.
Full textMajerska, Jana, Marianna Feretzaki, Galina Glousker, and Joachim Lingner. "Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1." Life Science Alliance 1, no. 4 (July 17, 2018): e201800121. http://dx.doi.org/10.26508/lsa.201800121.
Full textBechard, Laura H., Bilge D. Butuner, George J. Peterson, Will McRae, Zeki Topcu, and Michael J. McEachern. "Mutant Telomeric Repeats in Yeast Can Disrupt the Negative Regulation of Recombination-Mediated Telomere Maintenance and Create an Alternative Lengthening of Telomeres-Like Phenotype." Molecular and Cellular Biology 29, no. 3 (November 24, 2008): 626–39. http://dx.doi.org/10.1128/mcb.00423-08.
Full textIzumi, Hiroto, and Keiko Funa. "Telomere Function and the G-Quadruplex Formation are Regulated by hnRNP U." Cells 8, no. 5 (April 28, 2019): 390. http://dx.doi.org/10.3390/cells8050390.
Full textDe Vitis, Marco, Francesco Berardinelli, Elisa Coluzzi, Jessica Marinaccio, Roderick J. O’Sullivan, and Antonella Sgura. "X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells." Cells 8, no. 7 (July 12, 2019): 708. http://dx.doi.org/10.3390/cells8070708.
Full textColuzzi, Elisa, Stefano Leone, and Antonella Sgura. "Oxidative Stress Induces Telomere Dysfunction and Senescence by Replication Fork Arrest." Cells 8, no. 1 (January 3, 2019): 19. http://dx.doi.org/10.3390/cells8010019.
Full textCaslini, Corrado, and Jay L. Hess. "MLL Modulates Telomere Length in Mammalian Cells." Blood 108, no. 11 (November 1, 2006): 2209. http://dx.doi.org/10.1182/blood.v108.11.2209.2209.
Full textStock, Amanda, Kun Wang, Chengyu Liu, Ross McDevitt, Chongkui Sun, Yi Gong, and Yie Liu. "Age-Related Phenotypes Linked to Aberrant Expression and Localization of a Telomeric Protein." Innovation in Aging 5, Supplement_1 (December 1, 2021): 661–62. http://dx.doi.org/10.1093/geroni/igab046.2498.
Full textStock, Amanda, Kun Wang, Chongkui Sun, Chengyu Liu, Yi Gong, and Yie Liu. "A DNA Damage Response-Independent Mechanism for Telomere Shortening-Elicited Age-Related Pathologies." Innovation in Aging 4, Supplement_1 (December 1, 2020): 885. http://dx.doi.org/10.1093/geroni/igaa057.3268.
Full textAmato, Roberta, Martina Valenzuela, Francesco Berardinelli, Erica Salvati, Carmen Maresca, Stefano Leone, Antonio Antoccia, and Antonella Sgura. "G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells." Genes 11, no. 3 (March 13, 2020): 304. http://dx.doi.org/10.3390/genes11030304.
Full textBassham, Susan, Aaron Beam, and Janis Shampay. "Telomere Variation in Xenopus laevis." Molecular and Cellular Biology 18, no. 1 (January 1, 1998): 269–75. http://dx.doi.org/10.1128/mcb.18.1.269.
Full textDouglas, Max E., and John F. X. Diffley. "Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitro." Nucleic Acids Research 49, no. 10 (May 28, 2021): 5671–83. http://dx.doi.org/10.1093/nar/gkab416.
Full textStroik, Susanna, Kevin Kurtz, and Eric A. Hendrickson. "CtIP is essential for telomere replication." Nucleic Acids Research 47, no. 17 (August 5, 2019): 8927–40. http://dx.doi.org/10.1093/nar/gkz652.
Full textXu, Lifeng, and Elizabeth H. Blackburn. "Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules." Journal of Cell Biology 167, no. 5 (December 6, 2004): 819–30. http://dx.doi.org/10.1083/jcb.200408181.
Full textBryan, Christopher, Cory Rice, Michael Harkisheimer, David Schultz, and Emmanuel Skordalakes. "Structure of the Human Telomeric Stn1-Ten1 Complex." Acta Crystallographica Section A Foundations and Advances 70, a1 (August 5, 2014): C1587. http://dx.doi.org/10.1107/s2053273314084125.
Full textGupta, Aditi, Bor-Jang Hwang, Daniel Benyamien-Roufaeil, Sara Jain, Sophie Liu, Rex Gonzales, Robert A. Brown, Michal Zalzman, and A.-Lien Lu. "Mammalian MutY Homolog (MYH or MUTYH) is Critical for Telomere Integrity under Oxidative Stress." OBM Geriatrics 6, no. 2 (July 22, 2021): 1. http://dx.doi.org/10.21926/obm.geriatr.2202196.
Full textGu, Wei, Zihan Lin, Shengchao Zhao, Guanzhen Wang, Ziyi Shen, Wei Liu, Yi Cai, Kaibo Wang, Chunpeng Craig Wan, and Tingdong Yan. "Research Progress on G-Quadruplexes in Human Telomeres and Human Telomerase Reverse Transcriptase (hTERT) Promoter." Oxidative Medicine and Cellular Longevity 2022 (June 6, 2022): 1–11. http://dx.doi.org/10.1155/2022/2905663.
Full textCalado, Rodrigo T., Joshua A. Regal, Sachiko Kajigaya, and Neal S. Young. "Erosion of Telomeric Single-Stranded Overhang in Patients with Aplastic Anemia Carrying Telomerase Mutations." Blood 114, no. 22 (November 20, 2009): 1079. http://dx.doi.org/10.1182/blood.v114.22.1079.1079.
Full textPedram, Mehrdad, Carl N. Sprung, Qing Gao, Anthony W. I. Lo, Gloria E. Reynolds, and John P. Murnane. "Telomere Position Effect and Silencing of Transgenes near Telomeres in the Mouse." Molecular and Cellular Biology 26, no. 5 (March 1, 2006): 1865–78. http://dx.doi.org/10.1128/mcb.26.5.1865-1878.2006.
Full textBaumann, Peter, Elaine Podell, and Thomas R. Cech. "Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alternative Splicing." Molecular and Cellular Biology 22, no. 22 (November 15, 2002): 8079–87. http://dx.doi.org/10.1128/mcb.22.22.8079-8087.2002.
Full textKlingelhutz, A. J., S. A. Barber, P. P. Smith, K. Dyer, and J. K. McDougall. "Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells." Molecular and Cellular Biology 14, no. 2 (February 1994): 961–69. http://dx.doi.org/10.1128/mcb.14.2.961-969.1994.
Full textKlingelhutz, A. J., S. A. Barber, P. P. Smith, K. Dyer, and J. K. McDougall. "Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells." Molecular and Cellular Biology 14, no. 2 (February 1994): 961–69. http://dx.doi.org/10.1128/mcb.14.2.961.
Full textSmith, S., and T. de Lange. "Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomes." Journal of Cell Science 112, no. 21 (November 1, 1999): 3649–56. http://dx.doi.org/10.1242/jcs.112.21.3649.
Full textSoman, Aghil, Chong Wai Liew, Hsiang Ling Teo, Nikolay V. Berezhnoy, Vincent Olieric, Nikolay Korolev, Daniela Rhodes, and Lars Nordenskiöld. "The human telomeric nucleosome displays distinct structural and dynamic properties." Nucleic Acids Research 48, no. 10 (May 6, 2020): 5383–96. http://dx.doi.org/10.1093/nar/gkaa289.
Full textCesare, Anthony J., and Jack D. Griffith. "Telomeric DNA in ALT Cells Is Characterized by Free Telomeric Circles and Heterogeneous t-Loops." Molecular and Cellular Biology 24, no. 22 (November 15, 2004): 9948–57. http://dx.doi.org/10.1128/mcb.24.22.9948-9957.2004.
Full textCong, Yu-Sheng, Woodring E. Wright, and Jerry W. Shay. "Human Telomerase and Its Regulation." Microbiology and Molecular Biology Reviews 66, no. 3 (September 2002): 407–25. http://dx.doi.org/10.1128/mmbr.66.3.407-425.2002.
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