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Isdra, Záchia Eduardo. "Subsistent Parts: Aquinas on the Hybridism of Human Souls." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24114.
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In this dissertation, I argue for the philosophical consistency of Aquinas’ hybrid view of human souls - that is, the idea that human souls, and only human souls, are at once substantial forms and subsistent things. I contend that the best way to understand the ontological status of human souls according to Aquinas is by means of the concept of ‘subsistent parts’. Since Aquinas characterizes souls as parts of substances, I propose a mereological analysis of the different types of part in Aquinas, and I conclude that souls should be seen as metaphysical parts of substances. An influential contemporary view holds that Aquinas’ doctrine is inconsistent on the grounds that nothing could be an abstract (form) and a concrete (subsistent) at the same time. I respond to this view by denying the widespread notion that substantial forms are purely abstract entities. I hold that the best way to make sense of Aquinas’ twofold approach to human souls is by saying that substantial forms possess an element of
concreteness which is accounted for by the fundamental relationship between form and being. Finally, I address the question of taxonomy: how can we classify Aquinas’ view of the soul-body relation in light of the concepts that are currently used in philosophy of mind. I argue
that the notion of a subsistent part entails the concept of ‘part-dualism’, which I present as standing midway between substance-dualism and nonreductive materialism, and also as being ontologically richer than property-dualism. I conclude this dissertation with a refutation of the
idea championed by some prominent scholars that the existence of the soul is sufficient for the existence of the person.
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Merz, Sharon. "'Crocodiles are the souls of the community' : an analysis of human-animal relations in northwestern Benin and its ontological implications." Thesis, University of Exeter, 2018. http://hdl.handle.net/10871/32861.
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In this thesis I explore human-animal relations amongst the Bebelibe of the Commune of Cobly, in the northwest of the Republic of Benin, West Africa, with a focus on how they relate to their tikedimɔmɔnte (true totem(s), literally “interdict(s)-true”). I start with an historical review of totemism, the debates it generated and how these contributed to the recent ontological turn in anthropology. I then explore the theoretical ideas I use for my analysis, which include “presencing” and the “ontological penumbra” (J. Merz 2017b; J. Merz and S. Merz 2017). Presencing builds on semiotics by explaining how people make meaning present through their engagement in and with the world around them, whilst ontological penumbras are the shadowy spaces of limbo that affect our whole being and that people need to negotiate as part of making sense of their engagement with the world. As part of these theoretical frameworks, I examine the “onton”, as introduced by Johannes Merz (2017b). Ontons are experiential, agentive and relational entities that are the result of presencing processes. Ontons, however, cannot be divided into representations (signifiers) and represented (signified) as signs can. An engagement in the world between different entities in an ontonic and thus nonrepresentational sense necessitates my introducing further notions including shared “ontonity” (instead of shared humanity) and “ontonhood” (rather than personhood). I demonstrate how these theoretical ideas work with reference to human-animal relations primarily amongst the Bebelibe in the Commune of Cobly. In order to do this, I provide an in-depth, “thick description” (Geertz 1973) ethnography that explores how people perceive and relate to animals through hunting, domestication, attitudes to eating meat, animal commodification, reincarnation, shapeshifting and totemism. As part of my analysis I also examine the impact of Christianity on human-animal relations by exploring several incidents involving Christians and their tikedimɔmɔnte.
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Goodwin, Colin Robert, and res cand@acu edu au. "A Translation of The Quaestio Disputata de Spiritualibus Creaturis of St Thomas Aquinas, with Accompanying Notes." Australian Catholic University. School of Philosophy, 2002. http://dlibrary.acu.edu.au/digitaltheses/public/adt-acuvp18.16082005.
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Scope of the work - This research project involves two components. The first is a translation from Latin into English of St Thomas Aquinas’s Quaestio disputata de spiritualibus creaturis. This is an important, though largely neglected, work of St Thomas dating from 1267- 68, dealing with a range of issues relating to the two categories of created spirits recognised by Thomas, viz. angels and human souls. The perspective of the Angelic Doctor is principally, though not exclusively, that of philosophy rather than of theology. What is found in the disputed question is the development of a number of arguments, and the consequent taking up of a number of positions, that are the immediate source of what St Thomas has to say about angels and the human soul in the first part (prima pars) of his Summa Theologiae - a part which was completed by 1268. What he has to say about the Averroistic view that there is only one receptive intellect, and only one agent intellect, for all human beings (see Articles 9 and 10 of the disputed question) prepared the way for his crucially important polemical treatise of 1270, the De unitate intellectus contra Averroistas. The project provides a complete translation of the Quaestio disputata de spiritualibus creaturis which extends across eleven ‘articles’ addressing selected questions concerning angels and/or human souls, viz. matter/form composition, modes of union with (or separation from) matter, specific differences between angels, receptive intellect and agent intellect in human beings, and the distinction between the soul and its powers. Pages vi- vii of the Introduction to the project discuss the way in which the translation of the text of St Thomas has been approached. To cite one sentence: “An attempt has been made at all times to use a style of translation that is pleasantly readable, non-jarring, and non-pedantic” - but one that is subject to total fidelity to expressing the philosophical meaning of St Thomas. The second component of the project is eleven sets of notes (one hundred and seven pages in all), each set of which belongs to one or other of the eleven articles making up the text of St Thomas as translated. There is a degree of cross-referencing between some of the notes belonging to particular articles. The notes are of varying length and are concerned to facilitate an understanding of what the Angelic Doctor has to say in his Quaestio disputata de spiritualibus creaturis. Most of the notes fall into one or other of the following categories: biographical (providing information about a number of persons whose names appear in Thomas’s text), historical (giving information about institutions and events connected with the time, or life, of St Thomas), exegetical (explaining why a particular English translation of Thomas’s Latin has been used, or illustrating a point in the text by citations from other works of the Saint, or on occasion taking issue with some feature of the critical Latin text of Leo Keeler, S.J., on which the translation has been based), and ‘philosophical extension’ notes (seeking to amplify what St Thomas has been arguing in the disputed question on created spirits by considering related issues in other works of his, or by further exploration of a concept or notion used in the text but not dwelt on by Thomas). 2 Aim of the work - The aim of the project has been to make available an accurate, and attractive, English translation from thirteenth century Latin of an important work of Thomas Aquinas, and to support this activity with accompanying sets of notes. The achievement of appropriate scholarly standards has been a pervasive intention in all that has been undertaken.
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Cortez, Marc. "Embodied souls, ensouled bodies : an exercise in christological anthropology and its significance for the mind/body debate ; with special reference to Karl Barth's 'Church dogmatics' III/2 /." Thesis, St Andrews, 2006. http://hdl.handle.net/10023/145.
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Button, Mark. "Arsenic contaminated soils : human exposure and environmental toxicology." Thesis, University of Leicester, 2009. http://hdl.handle.net/2381/7797.
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Gupta, Kapil. "Dissection de TFIID, un facteur de transcription général humain : Études structurales etfonctionnelles des sous-ensembles du TFIID human." Thesis, Université Grenoble Alpes (ComUE), 2015. http://www.theses.fr/2015GREAV051/document.
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Les génomes eucaryotes sont très complexes et peuvent être très grands. Par exemple, le génome humain contient environ de 20 000 à 25 000 gènes codant pour des protéines. L'expression de ces gènes doit être strictement régulée à de nombreux niveaux (tels que l'organisation de la chromatine, la transcription des gènes, le traitement et l'exportation de l'ARN messager ainsi que la traduction) pour le bon fonctionnement de la machinerie cellulaire. De nombreuses protéines et complexes protéiques sont impliqués dans ces processus essentiels de régulation, tels que les remodeleurs de la chromatine, les activateurs, co-activateurs et répresseurs de la transcription et particulièrement la machinerie générale de transcription. Chez les eucaryotes, la transcription de gènes codant pour des protéines est appelée transcription génique de classe II, elle est catalysée par l'ARN polymérase II (Pol II). La transcription des gènes par la polymérase II nécessite l'interaction coopérative de plusieurs protéines et complexes protéiques afin de faciliter l'assemblage d'un complexe de pré-initiation (PIC) au promoteur de base. Le complexe de pré-initiation comprend l'ARN polymérase II et les facteurs de transcription généraux (GTFs) - TFIIA, TFIIB, TFIID, TFIIE, TFIIF et TFIIH ainsi que le complexe de Médiateur et une grande variété de co-activateurs transcriptionnels.Une étape fondamentale dans l'assemblage d'un complexe de pré-initiation est la reconnaissance du promoteur de base par le facteur de transcription général TFIID. TFIID est un complexe multi protéique d'environ 1,6 MDa. Chez l'homme, il comprend une vingtaine de sous-unités constituées de 14 protéines différentes - la protéine de liaison à la boite tata (TBP) et ses facteurs associés (TAFs 1 à 13). Une série d'études sur la TFIID humaine et ses sous-ensembles ont été réalisés depuis sa découverte il y a plus de 20 ans, cherchant à comprendre la structure et le mécanisme de ces facteurs de transcription général essentiel, cependant l'architecture de TFIID, ses activités, ses fonctions, ses rouages et ses mécanismes d'assemblage cellulaire reste largement incompris à ce jour.Cette thèse décrit les études biochimiques que nous avons effectuées sur trois sous-ensembles distincts de TFIID humain. Nous avons utilisé un certain nombre de techniques de biologie structurale : la cristallographie, la spectroscopie à résonance magnétique nucléaire (RMN) et la diffusion des rayons X aux petits angles (SAXs), pour étudier le complexe formé par les facteurs humains, associés à la protéine de liaison à la boite tata, TAF1 et TAF7. Ces études structurelles fournissent un aperçu détaillé sur l'interface d'interaction complexe de TAF1/TAF7, misent de concert avec des données disponibles dans la littérature, elles mettent en évidence la nature dynamique de l'interaction TAF1/TAF7 dans le complexe de TFIID humain.Dans une deuxième étude, nous avons analysé un complexe formé par TAF11, TAF13 et TBP en utilisant un panel de méthodes biophysiques et biochimiques : l'analyse électrophorétique de retard sur gel (EMSA), l'ultracentrifugation analytique (AUC), la chromatographie d'exclusion stérique (SEC) analyse, le pull-down, la spectrométrie de masse native et la spectrométrie de masse chimique à réticulation (CLMS). Ce complexe fait penser au complexe TAF1/TBP qui imite la boite tata.De plus, dans le cadre des efforts en cours au sein du laboratoire du Pr Imre Berger afin de déterminer la structure de l'holo-TFIID humaine, nous avons reconstitué un grand sous-ensemble de TFIID (900 KDa) appelé 9TAF, qui est composé de neuf différents facteurs associés de TBP. Nous avons effectué des études d'électro-microscopie par coloration négative sur le complexe 9TAF qui nous ont fourni des informations à faible résolution. Ces études ouvrent la voie à de futures études de cryo-EM sur le complexe 9TAF pour obtenir un modèle de plus haute resolutionEukaryotic genomes are highly complex and can be very large. For example, the human genome contains approximately 20,000-25,000 protein coding genes. Expression of these genes needs to be tightly regulated at many levels, including chromatin organization, gene transcription, mRNA processing and export and translation, for proper functioning of cellular machinery. Many proteins and protein complexes are involved in these essential regulatory processes, examples include chromatin remodelers, transcriptional activators and coactivators, transcriptional repressors and notably the general transcription machinery. Transcription of protein coding genes in eukaryotes is called Class II gene transcription, and is catalyzed by RNA polymerase II (Pol II). Gene transcription by Pol II requires the cooperative interaction of multiple proteins and protein complexes to facilitate the assembly of a preinitiation complex (PIC) at the core promoter. The PIC comprises Pol II and the General Transcription Factors (GTFs)- TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH, together with the Mediator complex and a large variety of transcriptional coactivators.A fundamental step in PIC assembly is recognition of the core promoter by GTF TFIID, a magdalton sized multiprotein complex. In humans, TFIID comprises about twenty subunits made up of 14 different proteins – the TATA box binding protein (TBP) and its associated factors (TAFs, numbered 1 to 13). A range of studies on human TFIID and its subassemblies have been carried out since its discovery more than two decades ago, to understand the structure and mechanism of this essential GTF, but the architecture of TFIID, its activities, its functions, its inner workings and the mechanisms of its cellular assembly have eluded detailed understanding to date.This thesis describes biochemical, biophysical, structural and functional studies carried out on three distinct human TFIID subassemblies. We used a number of structural biology techniques, including crystallization, nuclear magnetic resonance (NMR) spectroscopy and small angle X-ray scattering (SAXS) to analyse a complex formed by the human TBP associated factors TAF1 and TAF7. These structural studies provide detailed insights into the intricate interaction interface formed by TAF1 and TAF7, and, together with other data available from the literature, highlight the dynamic nature of the TAF1/TAF7 interaction in the human TFIID complex.In a second study, we analyzed a novel complex formed by TAF11, TAF13 and TBP using a range of biophysical and biochemical methods including electrophoretic mobility shift assay (EMSA), analytical ultracentrifugation (AUC), size exclusion chromatography (SEC) analysis, pull-down assay, native mass-spectroscopy and chemical cross-linking mass spectroscopy (CLMS). This complex is reminiscent of a so-called TATA-box mimicry discovered previously in a TAF1/TBP complex.As part of the ongoing efforts in the Berger laboratory to determine the structure of human holo-TFIID, we furthermore produced and purified a large (~900 kDa) TFIID subassembly called 9TAF, which is composed of nine different TBP associated factors. We carried out negative stain EM studies and random conical tilt (RCT) analysis on 9TAF to obtain low resolution structural information. These studies set the stage for future cryo-EM studies of this 9TAF complex to obtain a high(er) resolution model to decipher the inner workings of human TFIID
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Burgess, Scott Anthony. "The human body-soul complex in Plato's Timaeus." Thesis, University of Wales Trinity Saint David, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.683195.
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VELIATH, S. J. Cyril. "RAMANUJA'S CONCEPT OF THE INDIVIDUAL SOUL AND HUMAN FREEDOM." 名古屋大学印度哲学研究室 (Department of Indian Philosophy, University of Nagoya), 1991. http://hdl.handle.net/2237/19171.
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Al-Mustafa, W. A. "Phosphorus supply and plant growth in calcareous soils from south-east England and Saudi Arabia." Thesis, University of Essex, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356041.
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Willard, Robert. "The human soul of Christ in the christology of Athanasius." Theological Research Exchange Network (TREN), 1998. http://www.tren.com.
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Lang, Carol. "The hidden archive of historical human inhumations locked within burial soils." Thesis, University of York, 2014. http://etheses.whiterose.ac.uk/7427/.
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The study of soils within an archaeological context is often limited to the examination of landscapes and the environmental impact anthropogenic interactions have on their formation. Similarly, archaeological research into human inhumations has mainly focused on the rituals surrounding death, whilst determining socio-cultural practices and perceptions. The majority of research into the interactions of human interment and its effects on the surrounding soil has been limited to macromorphological investigation and elemental analysis. Historic human burials and their degradation products have not, to date, been investigated with regards to their impact on soil pedogenic processes. This research explores the hypothesis: soils and sediments immediately associated with the decomposition of human interment serve as valuable and under-utilised archaeological record. Grave soils were analysed using micromorphological and associated techniques to aid in the understanding of pedogenic processes and elemental composition of the grave soils incorporating burial remains. The analysis provided a comprehensive inventory of information regarding the archaeological inhumations within the burial soil through the spatial analysis of soil features in relation to the body. The analyses was undertaken on the undisturbed soil samples collected from around both single inhumations at sites in Mechelen, Belgium, Syningthwaite priory, England and South Leith, Edinburgh, and mass grave burials collected from Ridgeway, England and Fromelles, France, with control areas also being sampled, so effects of human decomposition of soil pedogenesis could be studies. Micromorphological analysis identified distinct patterns of pedality and depositional pedofeature development associated with the skull and pelvis sample regions around the burial, whilst also determining differences in pedogenesis to that of the control samples. SEM-EDS inorganic elemental analysis provided mapping of the degradation products emanating from the burials and migrating into the surrounding soil matrix, with elevated levels in depositional pedofeatures and fine material incorporated in all burials investigated, but particularly in soils from the skull and pelvic regions. Micromorphological analysis of soil thin sections from contexts of archaeological human inhumation can aid the detection of degradation products from the burial and identify artefacts derived from pre-burial treatment, some of which are no longer visible to the naked eye.
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Treash, Stephen Alden. "Jonathan Edwards' principles of awakening preaching." Thesis, University of Aberdeen, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294461.
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Jonathan Edwards is rightly titled America's first great theologian and philosopher, yet in terms of his historical influence he is foremost a preacher. This thesis links Edwards' philosophy to his preaching passion by demonstrating how his desire to establish a communication theory brought cohesion to his far-reaching philosophical interests. More specifically, this study shows how Edwards' speculative analysis on the composition of the human soul is motivated by his desire to configure a preaching strategy compatible with the soul's content and conduct. Jonathan Edwards' philosophy and its relation to his sermon writing is introduced in the first two chapters. The third chapter presents Edwards' conception of the human soul as an arrangement of mental powers which he calls "principles." Although the converted soul owns both natural and supernatural principles, Edwards' evangelistic preaching strategically targets the natural principles operating unaccompanied in the sinner. Focusing on Edwards' preaching to the unconverted, the next four chapters are devoted to an examination of the four natural principles: human reason; simple imagination; common affection and natural conscience. Each natural principle is placed within Edwards' communication theory while sermon extracts are called in to demonstrate the principle's function in Edwards' awakening preaching. The significance of this study is enhanced by the introduction of 100 unpublished sermons which are cited and used as background reference. These unpublished sermon portions offer a rare glimpse into Edwards' homiletic genius and in many cases appear in this study for the first time in print.
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Lazurca, Marius. "L'anthropologie du corps dans le monde romain sous le Haut-Empire." Lille : Atelier national de reproduction des thèses, 2004. http://catalog.hathitrust.org/api/volumes/oclc/56552922.html.
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Parise, Maria Cecilia Isatto [UNIFESP]. "As colorações da alma na análise da pessoa humana segundo Edith Stein." Universidade Federal de São Paulo (UNIFESP), 2014. http://repositorio.unifesp.br/handle/11600/39261.
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Neste trabalho, investigamos o conceito de alma e sua importância para a compreensão da pessoa humana segundo Edith Stein. Mostraremos, a partir de O problema da empatia (1916), A estrutura da pessoa humana (1932) e Ciência da cruz (1942), três obras de momentos distintos da vida da autora, um paralelo entre o modo como ela aprofunda a análise fenomenológica da alma, mantendo-se sempre vinculada ao método aprendido de Edmund Husserl, e sua vivência existencial de relação pessoal com Deus. Constatamos que em sua tese de 1916, O problema da empatia, Edith Stein já havia elaborado uma concepção estrutural da alma que passa a ser ampliada e aprofundada nas demais obras, sem sofrer grandes alterações. Desse modo, a análise fenomenológica do conceito de alma empreendida por Edith Stein nessas obras nos permite apontar para uma notável coerência e continuidade de seu pensamento nos diferentes períodos de sua vida, assim como sua estreita vinculação ao método fenomenológico de Edmund Husserl.
This study addresses the concept of the soul according to Edith Stein as a foundation for understanding her notion of human person. We will show through three studies published by the author at distinctly different moments: Zum Problem der Einfühlung (1916), Der Aufbau der menschlichen Person (1932) and Kreuzeswissenschaft (1942)], a parallel between the way she delves into the phenomenological analysis of the soul, very much influenced by the phenomenological method taught by Edmund Husserl, and her own existential experience in her intimate relation with God. We found that in her 1916 thesis, On the problem of Empathy, Edith Stein had already elaborated a structural concept of soul which, while enhanced and amplified, remained largely unaltered throughout her subsequent works. Thus, the phenomenological analysis of the concept of soul manifested in these three works, allows us to observe a profound coherence and continuity of thought throughout an significant period of her life, as well as her unswerving adherence to Edmund Husserl’s phenomenological method.
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Bouteneff, Peter C. "The theological value of Christ's human soul in the Cappadocian Fathers." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339779.
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Marturano, Eric. "Glory-Seeking: A Timeless and Puzzling Craving of the Human Soul." Thesis, Boston College, 2014. http://hdl.handle.net/2345/3865.
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Thesis advisor: Christopher ConstasPhilosophers throughout the ages have grappled with the concept of glory-seeking and have offered many different references, analyses, insights, and explanations. Three great thinkers in particular stand out above the rest: Plato, Thomas Hobbes, and Jean-Paul Sartre. While these three minds span from circa 420 BC all the way up to 1980 AD, they all would agree that glory-seeking certainly matters – they would most likely argue over the following: In what way? For Plato, glory-seeking is an inherent part of the human soul. It matters because it is an essential part of our being. Plato’s model for the soul found in The Republic as well as a comparable illustration in the Phaedrus expresses this claim most thoroughly. Additional support for the idea of glory-seeking being an existing precondition of humanity can be found in other ancient works as well, most notably Homer’s Iliad. A current example is professional athletes in the NFL risking their earning potential in order to play injured. For Hobbes, glory-seeking is a tool to be used for social advantage. It matters because it can be used it for advantage and power. Chapters X and XIII in The Leviathan most critically highlight this sentiment. Further support for the idea of glory-seeking being a weapon in the self-made man’s arsenal can be found in Jean-Jacques Rousseau’s Discourse on the Origin of Inequality. The largest modern-day example is celebrity culture: the news and entertainment factory so woven into current American culture, which is particularly embodied by the public behavior and lyrics of hip-hop artist Kanye West. For Sartre, glory-seeking provides an answer to existential angst. It matters because it helps us believe that we matter. The Sartre’s philosophical work, Being and Nothingness, as well as his existential novel, Nausea, provide ample evidence of this notion. More support for the idea of glory-seeking as a method of coping with the awareness one’s own existence can be found in Søren Kierkegaard’s The Present Age. Contemporary manifestations include the incessant self-promotion and self-presentation found on social media sites such as Twitter, Facebook, Instagram, and YouTube. The goal of this work is to first investigate glory-seeking for Plato, Hobbes, and Sartre and analyze what each thinker has to say on the matter. After that, modern examples and additional input from other relevant philosophers will be assessed within the overall context of glory-seeking for Plato, Hobbes, and Sartre. Finally, after everything has been considered, I will attempt to synthesize all that has been presented thus far while answering the question: Why does glory-seeking matter?
Thesis (BA) — Boston College, 2014
Submitted to: Boston College. College of Arts and Sciences
Discipline: College Honors Program
Discipline: Philosophy Honors Program
Discipline: Philosophy
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Opderbeck, David. "The end of the law : human evolution, neurolaw, and the soul." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/36118/.
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Lühe, Barbara von der [Verfasser]. "The fate of human decomposition products in soils / Barbara von der Lühe." Mainz : Universitätsbibliothek Mainz, 2016. http://d-nb.info/1104523078/34.
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Cotter-Howells, Jane. "Lead minerals in soils contaminated by mine-waste : implications for human health." Thesis, Imperial College London, 1991. http://hdl.handle.net/10044/1/8913.
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Silva, Sheila Paulino e. "O filosófo e a morte: um estudo sobre a Phroneis no Fédon de Platão." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/8/8133/tde-22032010-141911/.
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Em nossa leitura do diálogo Fédon, partiremos da análise dos motivos que Sócrates apresenta para não temer a morte, os quais se baseiam no discurso acerca da natureza da alma, para analisar os indícios que a racionalidade, mais precisamente a phronesis, oferece acerca dos limites entre o domínio supra-sensível e o domínio da vida humana. Tal reflexo, ao mesmo tempo em que denuncia sua natureza e orienta o homem verso ao exercício de filosofar, dá indicações acerca das limitações do intelecto para dizer sobre esse domínio, distinto do domínio da sensibilidade. Verificaremos a colaboração da phronesis na elaboração do discurso sobre a imortalidade, o qual justifica o destemor da morte, e os vários sentidos em que podemos compreendê-la no diálogo.In our searching of the dialogue Phaedo, we will start by analyzing the reasons that Socrates presents to not fear death, wich are based on discourse about the nature of the soul, to examine the evidence that rationality, specifically the phronesis, offers about the boundaries between the area of the super-sensitive and the human life´s area. Such reflection, while denouncing their nature and guides the man towards to the exercise of philosophy, also provides at same time references about the limitations of the intellect to say about this area, distinct of the area of sensitivity. We will check the collaboration of phronesis in the development of the discourse on immortality, wich justifies the fearlessness of the death, and the various ways in which we can understand it in dialogue.
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Yaldir, Hulya. "Ibn Sina (Avicenna) and Rene Descartes on the mind and body problem." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301933.
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You, Rui. "The occurrence of contaminants in crops grown under organic soil amendments and peri-urban soils: phytotoxicity and human health implications." Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/671348.
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L’agricultura moderna ha estat buscant contínuament mètodes efectius per satisfer la demanda d’aliments que augmenta exponencialment a nivell mundial. L’aplicació de residus orgànics com a fertilitzants o esmenes de sòl és una mesura molt utilitzada, ja que subministra nutrients de manera eficient i ràpida als cultius. De fet, des de 2015, la Comissió Europea ha proposat un pla d’economia circular que fomenta la utilització de biosòlids. No obstant això, la presència d’una àmplia gamma de contaminants com elements traça (ET), contaminants orgànics i contaminants emergents com antibiòtics (AB) i gens de resistència a antibiòtics (ARG), ha estat descrita en alguns fertilitzants orgànics. Les verdures poden incorporar els contaminants procedents de sòls fertilitzats amb residus orgànics, suposant així una amenaça per a la salut humana. Per aquesta raó, és necessària l’avaluació dels riscos que pot provocar la utilització d’aquests residus orgànics.
Els fertilitzants orgànics més emprats són les deixalles d’origen animal (fems), el compost (fonts vegetals o deixalles d’aliments) i les deixalles urbanes (llots de depuradora i residus domèstics). Actualment, no existeix cap estudi que avaluï la incorporació dels ET i AB per part de les plantes amb aquests tres tipus de fertilitzants orgànics, ni tampoc l’impacte de l’aplicació repetida de fertilitzants orgànics sobre les mateixes parcel·les. A més, aquesta aplicació repetida de llots de depuradora podria resultar en l’acumulació de Zn i Cu als sòls agrícoles, i la seva presència influiria en la incorporació d’altres contaminants.
Així doncs, en aquesta tesi doctoral s’aborden tres aspectes relacionats amb els contaminants en hortalisses en diferents activitats agrícoles: (1) aplicació de diferents dosis de diferents residus orgànics en sòls de cultiu, que té com a objectiu avaluar l’efecte d’aquesta fertilització en la incorporació de ET i AB en l’hortalissa, (2) aplicació reiterada de residus orgànics en sòls de cultiu i seguiment de la concentració de ET en hortalisses durant diferents cicles productius, amb l’objectiu d’avaluar l’impacte de la fertilització orgànica a llarg termini, i (3) aplicació de fangs de depuradora i diferents quantitats de Zn i Cu a sòls, amb l’objectiu d’avaluar l’efecte d’aquests metalls sobre l’acumulació d’altres contaminants com ET, AB i ARG en les hortalisses. A més d’això, en tots els casos s’ha avaluat el risc per a la salut humana associat al consum d’hortalisses.
En àrees periurbanes, el sòl agrícola pot rebre la contaminació potencial de contaminants procedents de sòls fertilitzats amb residus orgànics, però també els contaminants potencials derivats de les activitats urbanes. Aquests contaminants poden influir en el creixement i desenvolupament dels vegetals. En aquesta tesi, també s’ha desenvolupat un mètode simple i ràpid per tal d’avaluar la contaminació de sòls. Per a això, es van utilitzar dos índexs de creixement de plantes (taxa de germinació de llavors i allargament d’arrels en l’etapa inicial) en tres llavors de verdures per avaluar la contaminació química dels sòls en agricultura de proximitat.La agricultura moderna ha estado buscando continuamente métodos efectivos para satisfacer la demanda de alimentos que aumenta exponencialmente a nivel mundial. La aplicación de residuos orgánicos como fertilizante o enmienda de suelo es una medida ampliamente aceptada, ya que suministra nutrientes de manera eficiente y rápida a los cultivos. De hecho, desde 2015, la Comisión Europea ha propuesto un plan de economía circular que fomenta la enmienda del suelo con biosólidos. No obstante, la presencia de una amplia gama de contaminantes como elementos traza (ET), contaminantes orgánicos y contaminantes emergentes como antibióticos (AB) y genes de resistencia a antibióticos (ARG), ha sido reportada en algunos fertilizantes orgánicos. Las verduras pueden incorporar los contaminantes procedentes de suelos fertilizados con residuos orgánicos, amenazando la salud humana. Por esta razón, es necesaria la evaluación de los riesgos que puede provocar la aplicación de estos residuos orgánicos. Los fertilizantes orgánicos más utilizados son los desechos de origen animal (estiércol), el compost (fuentes vegetales o desechos de alimentos) y los desechos urbanos (lodos de depuradora y residuos domésticos). Actualmente, no existe ningún estudio que evalúe la incorporación de ET y AB por parte de las plantas con estos tres tipos de fertilizantes orgánicos, ni tampoco el impacto de la aplicación repetida de fertilizantes orgánicos sobre las mismas parcelas. Además, esta aplicación repetida de lodos de depuradora resultaría en la acumulación de Zn y Cu en el suelo modificado, y su presencia puede influir en la incorporación de otros contaminantes. Por tanto, en esta tesis doctoral se abordan tres aspectos relacionados con los contaminantes en hortalizas en diferentes actividades agrícolas: (1) aplicación de diferentes dosis de distintos residuos orgánicos a suelos de cultivo, que tiene como objetivo evaluar el efecto de esta fertilización en la incorporación de ET y AB en la hortaliza, (2) aplicación reiterada de residuos orgánicos en suelos de cultivo y seguimiento de la concentración de ET en hortalizas durante diferentes ciclos productivos, cuyo objetivo es evaluar el impacto de la fertilización orgánica a largo plazo, y (3) aplicación de lodos de depuradora y diferentes cantidades de Zn y Cu al suelo, con el objetivo de evaluar el efecto de estos metales sobre la acumulación de otros contaminantes como ET, AB y ARG en las hortalizas. Además, en todos los casos se evaluó el riesgo para la salud humana asociado al consumo de hortalizas. En áreas periurbanas, el suelo agrícola puede recibir la contaminación potencial de contaminantes procedentes de suelos fertilizados con residuos orgánicos, pero también los contaminantes potenciales derivados de las actividades urbanas. Estos contaminantes pueden influir en el crecimiento y desarrollo de los vegetales. En esta tesis, también se desarrolló un método simple y rápido para evaluar la contaminación del suelo. Para ello se utilizaron dos índices de crecimiento de plantas (tasa de germinación de semillas y alargamiento de raíces en la etapa inicial) en tres semillas de hortalizas para evaluar la contaminación química del suelo en agricultura de proximidad.
Modern agriculture has been continually searching for effective methods to meet the exponentially increasing food demand. Amending soil with fertilizers has been widely adopted, as it could efficiently and fast supply nutrients to vegetables. Since 2015, the European Commission has proposed a circular economy plan which encourages the soil amendment with biosolids. Nevertheless, the presence of a wide range of contaminants, such as trace elements (TEs), organic pollutants, and emerging pollutants such as antibiotics (ABs) and antibiotic resistance genes (ARGs), has been widely reported in many organic fertilizers. Vegetables can absorb the contaminants from the amended soil, and further threaten human health. For this reason, risk assessment of organic fertilizer applications is necessary. The most commonly used organic fertilizers are animal-based waste (manure), compost (plant sources or food waste), and urban waste (sewage sludge and household waste). Currently, no study evaluates the plant uptake of TEs and ABs under these three organic fertilizers, nor research evaluates the impact of repeated organic fertilization. Additionally, multiple application of sewage sludge might result in the accumulation of Zn and Cu in amended soil, and their presence would influence uptake of other contaminants. Therefore, in this doctoral thesis, three aspects related to the contaminants in vegetable under different agriculture activities are addressed: (1) amending soils with different doses of different organic fertilizers, which aims to assess the impact of organic fertilizers on the occurrence of TEs and ABs in vegetables, (2) repeated amending soil with organic fertilizers and monitoring the variation of TEs concentrations in vegetables of different productive cycles, which aims to assess the impact of long-term organic fertilization, and (3) amending soils with sludge and different amounts of Zn and Cu, which aims to assess the effect of Zn and Cu on the accumulation of TEs, ABs, and ARGs in vegetables. Furthermore, in every case the risk to human health associated with the consumption of vegetables was evaluated. In peri-urban area, the agricultural soil may receive the potential pollution from fertilizer, but also from potential contaminants due to urban activities. Those pollutants would influence the growth and development of vegetables. In this thesis, a simple and rapid method to assess soil pollution was also developed. Here, we use two plant growth indexes (seed germination rate and root elongation at the initial stage) for three vegetable seeds to assess soil chemical contamination on proximity agriculture.
Universitat Autònoma de Barcelona. Programa de Doctorat en Ciència i Tecnologia Ambientals
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Legge, David Dominic. "The individuation of the human soul after death Aquinas's Esse terminatum argument /." Online full text .pdf document, available to Fuller patrons only, 2004.
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Lundström, Johanna. "Innocence and Experience : Deconstructing Blake's “Two Contrary States of the Human Soul”." Thesis, Karlstads universitet, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-71478.
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This essay analyzes poems and deconstructs binary oppositions in William Blake's Songs of Innocence and of Experience. By analyzing a number of poems, the essay exemplifies how Blake not only creates binary oppositions, but how he also deconstructs them. The essay focuses on the central binary opposition of innocence and experience, but also shows different binary oppositions to further show how Blake is setting up and deconstructing binary oppositions. The essay will argue that Blake can be considered an early deconstructionist due to his use of binary oppositions, as well as Blake intentionally creates binary oppositions.
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Pilaev, Martin. "Développement de vaccins sous-unitaires contre le métapneumovirus humain." Master's thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/32639.
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Le métapneumovirus humain (hMPV) est un virus qui circule dans la population humaine depuis plus de70 ans et a été isolé pour la première fois en 2001. Il est la troisième cause mondiale en lien avec les hospitalisations d’enfants pour maladies aigües des voies respiratoires supérieures et inférieures. Il est responsable d’une multitude de complications chez les jeunes enfants, les personnes âgées ainsi que les personnes immunosupprimées. À ce jour, il n’existe aucun vaccin commercial contre le hMPV. Dans les récentes années, la protéine de fusion F, qui est le principal antigène viral, a fait l’objet d’une multitude d’essais principalement pré-cliniques en vaccination. La découverte que, chez le virus respiratoire syncytial (VRS), la protéine F stabilisée en forme pré-fusion est plus immunogène a fourni de nouvelles pistes pour le développement vaccinal. Pour ces raisons, l’objectif de ma maîtrise est le développement d’un vaccin sous-unitaire à base de protéine F-hMPV stabilisée en pré-fusion et son test chez le modèle de la souris BALB/C pour vérifier son potentiel protecteur. Nos études ont démontré qu’il n’y a pas de différence significative, en termes d’immunogénicité, entre la forme pré- et post-fusion de la protéine F chez le hMPV. Les essais d’immunogénicité ont également démontré la nécessité de l’ajout de l’adjuvant alum pour élucider une réponse immunitaire chez la souris BALB/C. Les immunisations par les protéines adjuvantées ont démontré le développement d’anticorps neutralisants. Suite à l’infection, la réplication virale pulmonaire a été diminuée sous le seuil de détection des techniques utilisées, mais l’inflammation pulmonaire a persisté. Les vaccins adjuvantés n’ont pas influencé la perte de poids chez la souris, mais ont amélioré les autres symptômes cliniques tels l’activité physique et le poil ébouriffé. Les vaccins F-hMPV sans alum présentent certaines caractéristiques de réponse immune exagérée (titres en anticorps neutralisants nuls; état physique détérioré) et devront être analysés davantage. Les vaccins F-hMPV avec alum n’ont pas démontré des signes de réponse immune exagérée, suite à l’infection par le hMPV, malgré une réponse immune de type Th2 plus forte. Globalement, malgré une réduction des titres viraux à un seuil indétectable, aucun des vaccins n’a protégé complètement le modèle murin contre l’infection par le hMPV. Les vaccins développés au cours de ces études ouvrent la voie à de nouvelles stratégies d’immunisation, de nouveaux essais de vaccination en combinaison avec d’autres adjuvants et peuvent servir de base pour le développement d’un vaccin efficace contre le hMPVThe human metapneumovirus has been first isolated in 2001 despite its circulation in the human population for more than 70 years. HMPV is the third leading cause of children hospitalisations associated with acute respiratory tract infections. Complications occur commonly in young children, the elderly and the immunocompromised. To this day, no vaccine has been licensed for use against hMPV. In recent years, the F protein, considered the most immunodominant antigen, has been the target of many pre-clinical vaccine trials. The discovery, for RSV, that a prefusion bound F protein is more immunogenic than post-fusion has encouraged new vaccination approaches. Based on this discovery, the aim of this project is the development of a prefusion bound F-hMPV subunit vaccine and testing its potency to protect the BALB/C model. Following challenge, no significant difference between potentially prefusion bound proteins and wild type protein was observed. Immunisation trials revealed the necessity of adding an adjuvant, alum in this case, to elicit an immune response in mice. Neutralizing antibodies were observed with F-hMPV vaccines containing the alum adjuvant. Post-immunisation challenge trials revealed reduction of lung viral replication below detection levels and persisting inflammation. Weight loss was not affected by vaccination, but animals immunised with adjuvanted F-hMPV proteins exhibited better physical condition and no signs of disease such as diminished activity and ruffed fur. F-hMPV vaccines without alum exhibited some characteristics of enhanced disease (no neutralizing antibodies; affected physical condition) and require further analysis. Enhanced disease was not observed in the F-hMPV adjuvanted groups despite higher Th2/Th1 ratios with adjuvanted proteins . None of the vaccines tested were able to fully protect the mouse model upon challenge. Vaccines developed in this study will be useful in future trials and could be tested with other adjuvants or vaccination strategies.
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Marques, Maria Janaina Brenga. "O livre-arbítrio em Agostinho." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/8/8133/tde-07122012-121726/.
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Para considerar o livre-arbítrio da vontade, Agostinho deve mobilizar concepções já estabelecidas sobre a natureza divina, sobre a natureza do mal e também sobre a natureza da alma humana. À medida que tais concepções se modificam, o livre-arbítrio da vontade assume contornos diversos até obter sua forma mais acabada, na qual se revela como raiz do mal moral sem nada referir à autoria divina e na qual se revela também como essencialmente viciado sem ter outra alternativa senão a de aceitar a ajuda divina. Assim, se de um lado o livre-arbítrio da vontade não exige relacionar Deus com a causa do mal, de outro lado exige relacionar Deus com a única forma de corrigir o mal. Nosso trabalho tem o objetivo de analisar as tramas conceituais supostas na concepção de livre-arbítrio, vendo nesta uma chave de leitura com força de evidenciar certa lógica interna no movimento envolvendo a conversão de Agostinho ao cristianismo.In order to consider the free choice of the will, Augustine has to mobilize concepts already established about the divine nature, the nature of evil and also the nature of the human soul. As such concepts change, the free choice of the will takes on different features until it reaches its most defined form, in which it is revealed as the origin of moral evil without reference to the divine authorship and in which it is also revealed as essentially vicious without any alternative but to accept divine aid. Therefore, if on the one hand the free choice of the will does not entail a relationship between God and the cause of evil, on the other hand it requires the relationship between God and the only way to stop evil. The objective of this work is to analyse the conceptual webs entailed in the concept of free choice, viewing it as a reading key capable of evidencing a certain internal logic in the movement involving Augustine\'s conversion to Christianity.
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Prima, Frank Joseph. "The human soul as form and Hoc aliquid according to St. Thomas Aquinas." Online full text .pdf document, available to Fuller patrons only, 2004. http://www.tren.com.
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Churchouse, Matthew John. "Renewing the soul : towards an enhanced Pentecostal philosophical theological doctrine of human constitution." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8009/.
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Having given a fresh historical overview of Pentecostal thought concerning the doctrine of human constitution, and so ascertained the trajectory Pentecostal theology is on concerning this doctrine, this thesis identifies Amos Yong and then Veli-Matti Kärkkäinen as significant voices towards the end and present of the trajectory, with the potential to influence its future direction. The thesis highlights both scholars’ assumption that any dualistic view of human constitution - specifically, understanding the soul as a distinct immaterial (and after death, separable) entity from the body - is theologically and philosophically problematic, and charts their alternative proposal(s) of an emergent monist view of human constitution. Responding to them, the thesis counters their theological and philosophical challenges, and further contends that their emergent monist proposals suffer much greater problems. It then argues for and constructs an enhanced Pentecostal view of human constitution - one more consistent with Pentecostal theological emphases, and also stronger philosophically than Yong’s and Kärkkäinen’s - proposing a new ‘Enspiritable Dualist’ view, by renewing the soul. Through giving it suitable prominence in Pentecostalism’s theology of constitution, and by establishing the centrality of the S/spirit in the new model, the soul is renewed, in turn, redirecting the trajectory’s future.
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Perez-Cespedes, Martin. ""A Journey from the Mind to the Soul" Museum of the Human Body." Thesis, Virginia Tech, 2010. http://hdl.handle.net/10919/42665.
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The inspiration for the development of this project - The Museum for the Human Body in Georgetown, Washington D.C. - was based on a study of the anatomy of movement and its Relationship to space. â A Journey from the mind to the soul’ is the connective experience linking the spaces of the project (body, mind and soul). This study is inspired by ideas from the early Chinese, Egyptian and Aristotelian philosophies as well as the drawings of Leonardo da Vinci in searching for the â sensus communis' as the location of the soul within the body.Master of Architecture
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Defoe, Phillip Peterson. "Urban brownfields to gardens : minimizing human exposure to lead and arsenic." Diss., Kansas State University, 2014. http://hdl.handle.net/2097/17584.
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Doctor of PhilosophyDepartment of Agronomy
Ganga M. Hettiarachchi
Urban gardens have been a popular re-use option in the transformation of brownfields—located in older industrialized cities and near peri-urban developments. They provide accessible, available, and affordable supplies of fresh fruits and vegetables, effectively reducing the enigma of “food deserts” across U.S. cities. However, direct (soil ingestion, inhalation) and indirect (soil-plant-human) human exposure concerns about real or perceived trace element contamination in urban soils persist due to previous use. Elevated lead (Pb) and/or arsenic (As) concentrations were found at two (Tacoma and Seattle, WA) urban gardens. The Tacoma site was contaminated with Pb (51 to 312 mg kg-1) and As (39 to 146 mg kg-1), whereas soil Pb at the Seattle site ranged from 506 to 2,022 mg kg-1, and As concentrations were < 20 mg kg-1. Experimental design at both sites was a randomized complete block with a split-plot arrangement (main plots: biosolids/compost vs. non-amended control; sub-plot: plant type). Tacoma site treatment included a Class A biosolids mix (TAGRO) with dolomite. The Seattle site was amended with Cedar-Grove Compost (CGC) plus dolomite. Efficacy of biosolids/compost amendment in reducing Pb and As concentrations was evaluated using root, leafy, and fruit vegetables. Soil Pb and As bioaccessibility were also evaluated. Food chain transfer of Pb and As in vegetables due to surface contamination of produce samples were evaluated on the basis of cleaning procedures. A laboratory incubation study and a controlled greenhouse experiment were conducted on soils collected from the Tacoma site. Effectiveness of addition of laboratory synthesized ferrihydrite (Fh: iron oxyhydroxide) and TAGRO mix, each alone or in combination were screened and tested on the Pb and As co-contaminated Tacoma soil. Extended X-ray Absorption Fine Structure (EXAFS) spectroscopy studies of Pb and As were conducted on incubation study samples to understand treatment-induced Pb- and As-speciation changes. Dilution of soil Pb (10 to 23%) and As (12 to 25%) were observed for biosolids amendment at the Tacoma site, while CGC amendment resulted in 20 to 50% dilution in soil Pb at the Seattle site. Biosolids and CGC amendments reduced Pb concentrations in the vegetables by 50% to 71%. At both sites, Pb concentrations of root vegetables exceeded the MLs established by the Food and Agriculture Organization (FAO) and the World Health Organization (WHO). Arsenic concentrations in vegetables were below an estimated ML and were reduced by 46% to 80% when grown on biosolids amended soils. Laboratory cleaning further reduced Pb and As food-chain transfer in vegetables grown in contaminated urban soils. Laboratory incubation and greenhouse studies showed dissolution of Pb in TAGRO plus Fh, and Pb concentrations in Fh amendments were significantly lower than the other amendments. Bioaccessible Pb and As were low. Significant reductions in bioaccessible As were observed when soils were amended with both TAGRO and Fh. X-ray absorption spectroscopy results indicated that chloropyromorphite-like (stable Pb phosphates) phases were the most dominant Pb species. Arsenic existed mainly as As5+, scorodite (FeAsO4•2H2O)-like species in all the treatments ranging from about 60% (control) to about 70% (TAGRO plus ferrihydrite). Amendments utilizing both biosolids and Fh significantly reduce human exposure risks present in urban soils contaminated with Pb and As.
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SALVETE, MARIE-JOSE. "Les infections a parvovirus humain b19 : une pathologie sous-estimee ?" Limoges, 1989. http://www.theses.fr/1989LIMO0133.
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Constantini, Marc. "Le virus respiratoire syncytial : identification des sous-groupes par immunofluorescence et étude de la gravité des infections en fonction du sous-groupe." Caen, 1991. http://www.theses.fr/1991CAEN3078.
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Hung, Chui-shan Bonnie, and 洪翠珊. "Human impact on the structure and water status of urban park soils in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31226103.
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Borau, Stephan A. "Soul mapping in the workplace, creating organizations that better reflect the whole human being." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0016/MQ45862.pdf.
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Gurr, Jens Martin. "The human soul as battleground : variation on dualism and the self in English literature /." Heidelberg : Universitätsverlag Winter, 2003. http://catalogue.bnf.fr/ark:/12148/cb392614894.
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Vanden, Bout Melissa Rovig. "Thomas Aquinas and the Generation of the Embryo: Being Human before the Rational Soul." Thesis, Boston College, 2013. http://hdl.handle.net/2345/bc-ir:104090.
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Thesis advisor: Peter KreeftThomas Aquinas is generally viewed as the chief proponent of the theory of delayed animation, the view that the human embryo does not at first have the rational soul proper to human beings. Thomas follows Aristotle's embryology, in which an embryo is animated by a succession of souls. The first is a nutritive soul, having the powers of growth, nutrition, and generation. The second is a sensitive soul, having the additional powers of locomotion and sensing. The third and final soul is the human, or rational soul, which virtually includes the nutritive and sensitive souls. Because Thomas holds that there is only one substantial form of a composite, none of these forms overlap to provide continuity. It is therefore exceedingly difficult to speak of the embryo as one enduring subject through the succession of souls. Moreover, because of the way that the nutritive soul is associated with plants, and the sensitive soul is associated with animals, interpreters generally hold that for Thomas the embryo is first a plant, then an animal, and with the advent of the rational soul, finally a human being. Those who write about the ontological status of the embryo assume that delayed animation necessarily entails delayed hominization, that is, that the embryo only becomes human at a later stage of its development, when it receives the rational soul. Those who hold a delayed animation view of the embryo often invoke Thomas' schedule of successive souls in the embryo as a model for viewing it as not yet human in early stages of development, linking hominization to the ability to perform intellectual operations. That Thomas specifies that a body must be sufficiently organized before the advent of the rational soul seems to them to solidify their view of the embryo as not sufficiently organized to be truly human. Additionally, even outside of an explicitly Thomist framework, Thomist metaphysical principles are often invoked in arguments that center on twinning and totipotency of blastomeres in the early embryo, and whether that early embryo is one individual if it is potentially many. Those who hold immediate animation views (i.e., the embryo receives the rational soul at once, with no mediate states) often adopt the strategy of importing modern data on the internal organization and self-directed development of the embryo, and argue that if only Thomas had known that the zygote was not unformed and undifferentiated, that it has within itself all it needs to become a mature adult human, he would have held that the embryo is immediately suited to receive the rational soul, and thus is human from conception. In this way they attempt to employ a change in scientific data to negate the need for a succession of forms in the embryo. The author identifies the being of the human embryo as a prior metaphysical problem within Thomas' work, and advances a different interpretation of his views: that the embryo, even before the advent of the rational soul, is human. To establish this claim, she traces the problems which emerge in the current debate about when the embryo becomes human, and argues that contrary to expectation, it is not necessary to equate immediate rational animation with immediate hominization, demonstrating that all other approaches yield results entirely untenable for Thomas. A survey of texts reveals that Thomas did in fact view the embryo as human before the rational soul, though he does not methodically work out the implications of that view in a number of areas. Moreover, a distinction based on a passage in Aristotle's Generation of Animals with regard to an additional meaning of generation may resolve the ambivalence in Thomas' account of the embryo as passive under the formative power of the father's semen. Finally, a third meaning of generation is offered to show that Thomas recognized and wished to resolve the difficulty of explaining the continuity and identify of the embryo in the succession of souls. What results is an immediate hominization view of the embryo that, because it accommodates Thomas' succession of souls and does not depend upon importing modern biological data on the embryo, is consistent with Thomas' account, and is thoroughly cognizant of the way Thomas viewed human nature and the final end of human being
Thesis (PhD) — Boston College, 2013
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Philosophy
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Panahpour, Darius Y. "An assessment of the human soul and its knowledge of God in the Neoplatonic thought of Marsilio Ficino." Theological Research Exchange Network (TREN), 2005. http://www.tren.com.
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Monfouilloux, Sylvaine. "Etude de la structure et de l'évolution d'une région de translocations sous télomériques chez l'homme." Rouen, 1997. http://www.theses.fr/1997ROUES065.
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Les extrémités des chromosomes comportent le télomère puis la région sous télomérique. Ces deux domaines se distinguent des autres régions chromosomiques car ils évoluent par des échanges entre les chromosomes hétérologues. Le télomère est une structure spécialisée constituant la fin des chromosomes et indispensable à leur stabilité. Il joue un rôle important dans l'organisation spatiale des chromosomes en particulier dans l'agglutination des extrémités chromosomiques en périphérie nucléaire. La région sous télomérique, adjacente au télomère est très redondante entre les chromosomes hétérologues et se termine avec les séquences uniques spécifiques à chaque chromosome. Sa fonction ainsi que sa structure ne sont pas bien connues. Plusieurs familles de séquences répétées y sont présentes. Certaines sont localisées uniquement à proximité du télomère, d'autres comme les minisatellites sont en majorité localisées dans les derniers mégabases des chromosomes. Nous avons étudié en détail une région sous télomérique présente sur une dizaine de chromosomes chez tous les individus. Nous montrons qu'elle s'est propagée par des translocations successives de domaines chromosomiques terminaux de 80 a 200 Kb, impliquant des processus de recombinaison divers. Ces translocations se sont produites après la séparation de l'homme et du chimpanzé. La stabilité de la région apparaît variable suivant les chromosomes ce qui se traduit par un polymorphisme des localisations de la région entre les individus. Cette région sous télomérique a évolué de façon très différente entre l'homme et le chimpanzé. Nous proposons que cette évolution pourrait être conditionnée par la présence de gènes adjacents à la région sous télomerique. Nous avons en effet montré que des gènes ubiquitaires se trouvent à quelques dizaines de Kb en aval de la région sous télomérique. Leur expression pourrait être influencée par la chromatine adjacente, c'est à dire par la nature de la région sous télomérique. Nous proposons enfin que l'évolution de la région sous télomérique constitue un modèle pour l'étude de l'évolution du génome humain.
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Kwast-Greff, Chantal. "Distorted bodies and suffering souls : women in Australian fiction, 1984-1994." Toulouse 2, 2001. http://www.theses.fr/2001TOU20031.
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Ma thèse étudie l'image de la femme dans la fiction contemporaine australienne écrite par des femmes, en se concentrant sur la distorsion des corps et la souffrance psychique. Les outils forgés par la psychanalyse et l'humanisme, et les théories féministes, me permettent de construire un sens de ces histoires d'anorexie, de boulimie, d'auto-mutiliation et de meurtre d'enfant, une mise en relation du corps et de l'âme. Ma thèse est que le corps déformé fonctionne comme un signe, à la fois réaction et langage, qui est interprété socialement comme folie. Les personnages féminins opprimés inscrivent leur souffrance psychique sur le canevas de leur corps. La stratégie mise en place pour “guérir” la femme considérée folle fonctionne davantage comme une stratégie pour la soumettre et la faire taire. Les écrivains-femmes que je considère constuisent le corps de leur texte comme palimpseste, de la même façon que le corps de la femme, mutilé, scarifié ou affamé est un palimpseste. Ces textes fonctionnent à la fois comme un discours de rébellion et d'acceptation du discours patriarcal en vigueur. Je propose de lire cette fiction comme une représentation d'un réel. La problématique centrale est alors celle du téléscopage de la fiction et du réel. L'identification-miroir des lecteurs transmuent ces narrations en “Bildungsroman”, le risque inhérent étant dans l'acceptation et le renforcement des stéréotypes sexistes et des comportements patriarcaux oppressifs. Je considère que le corps féminin dans les oeuvres considérées et dans le monde du réel reflété porte les marques et cicatrices de l'histoire des femmes, l'histoire de femmes qui se battent, l'histoire de femmes qui survivent. Et que les femmes qui se battent seront les femmes qui gagnentThis thesis is looking at female bodies and suffering in contemporary Australian fiction written by women. I am using the tools forged by psycho-analysis and humanism, and the feminist theories to work my way through the meanders of these narratives of anorexia, bulimia, and self-mutilation and baby-murder towards a deeper layer of meaning of body and soul, and offer an interpretation of this fiction in relation to the world of “real” women in contemporary white Australia. My thesis is that the body distorted functions as a sign, both reaction and language, which is interpreted as madness. The oppressed female characters inscribe the suffering of their souls on the canvass of their bodies. Ths strategies to cure “mad” women appear more as strategies to tame them than to heal them. The female writers I am looking at construct the body of their text as a palimpsest, in the same way as the body of the woman, mutilated, scarred or starved, is a palimpsest. These texts function as a discourse of defiance and acceptance of the discourses of patriarchy in force. The central issu is the conflation of fiction and reality. The mirror-identification of the reader transmutes these narratives into potential Bildungsromane. The risk lies then in the acceptance and re-inforcement of sexist / gender stereotypes. I argue that the female body bears the marks and scars of the history of women, the history of fighters and survivors. And that women who fight can become women who win
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Lazurca, Marius. "L'anthropologie du corps dans le monde romain sous le Haut-Empire." Paris 4, 2003. http://www.theses.fr/2002PA040227.
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Dans ce travail, nous analysons les significations les plus importantes du corps humain, telles qu'elles sont apparues dans le monde romain sous le Haut-Empire. Notre analyse prend en compte des textes philosophiques, religieux, juridiques et médicaux. Dans la période choisie, l'hermeneutique du corps est appelée à fournir des réponses à des questionnements très divers, comme : la définition d'une éthique du pouvoir pour l'aristocratie romaine par les moyens de la philosophie stoïcienne, la transposition du droit conjugal, la formation des communautés religieuses. Notre objectif est d'analyser la fonction des interprétations de la corporalité dans la constitution de ces phénomènes culturels de l'époqueIn this thesis, we analyse the most important meanings assumed by the human body, as they appear in the roman world of the Early Empire. Our analysis is based on the philosophical, religious, juridical and medical texts. In the period chosen for analysis, the hermeneutics of the human body is called to furnish the answers to a variety of questions, such as the definition of an ethics of power for the roman aristocracy given by the stoic philosophy, the transformation of the connubial law, or the setting up of the religious communities. Our objective is to analyse the fonction of the interpretations given to corporality within the making of these cultural phenomena of the epoch
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Schnabl, Ruth. "Gravity-bound the articulation of the body in art and the possibility of community /." Diss., Online access via UMI:, 2008.
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Martinez, Cingolani Carolina. "Differential Effects of the Cytokine Thymic Stromal Lymphopoietin on Human Dendritic Cell Subsets." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA11T083/document.
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Une fois activées, les cellules dendritiques (DCs) migrent dans les organes lymphoïdes ou elles exercent leur rôle de cellules présentatrices d’antigène professionnelles. Elles sont capables d’activer et d’induire la différenciation des lymphocytes T naïfs en différentes sous-populations de lymphocytes T auxiliaires. L’ajustement de la réponse lymphocytaire T au type d’inflammation est assuré par les DCs à deux niveaux. Premièrement, grâce à leur plasticité, les DCs adaptent leur comportement en fonction de la combinaison de signaux issus du microenvironnement inflammatoire. Deuxièmement, il existe différentes sous-populations de cellules dendritiques ayant de différentes spécialisations fonctionnelles.Mon travail de thèse s’est concentré sur l’étude de la diversité des réponses des sous-populations de cellules dendritiques humaines suite à la stimulation par la cytokine lymphopoïetine stromale thymique (TSLP). Cette cytokine est secrétée par les cellules épithéliales et la peau au cours de l’inflammation. La TSLP active principalement les DCs myéloïdes, induisant celles-ci à secréter les chimiokines inflammatoires CCL17 et CCL22. Les DCs activées par la TSLP (TSLP-DCs) induisent une réponse inflammatoire de type Th2, et sont impliquées dans le développement de l’allergie. La comparaison systématique de la réponse à la TSLP par les sous-populations de DCs du sang, BDCA1+ et BDCA3+, nous a permis de montrer que ces deux sous-populations sont activées par la TSLP. Toutefois, nos résultats montrent que la TSLP, en synergie avec le TGF-β, induit la différenciation des DCs BDCA-1+ en cellules de Langerhans, mais pas celle des DCs BDCA-3+. De plus, la TSLP induit la migration cellulaire et la sécrétion de chimiokines seulement chez la sous-population de DCs BDCA-1+. Des analyses complémentaires des mécanismes impliqués dans la migration des DCs BDCA-1+ en réponse à la TSLP révèlent que, d’une part la TSLP est indispensable à l’induction de la migration et d’autre part, qu’un récepteur de chimiokines, sensible à la Toxine Pertussique serait impliqué. Au final, nos résultats révèlent (i) de nouvelles capacités des DCs en tant que cellules précurseurs, (ii) de différentes propriétés fonctionnelles des sous-populations de DCs en réponse à la stimulation par la TSLP, (iii) et démontrent la complexité des mécanismes impliqués dans la migration des DCs induite par la TSLPOnce activated, Dendritic Cells (DCs) migrate to the lymphoid organs and exert their role as professional antigen presenting cells. They are able to induce the activation and differentiation of naïve T cells into different types of T helper cells. The T cell response must be suited to the type of inflammation. This is ensured by DCs at two levels. First DCs are functionally plastic. This means that their behavior is subdued to the integrated signals coming from the inflammatory microenvironment. Secondly, the DC population is diverse. Indeed, different DC subsets have different functional specializations. My thesis was focused on the differential response of human DC subsets to Thymic stromal lymphopoietin (TSLP). This cytokine is secreted by inflamed skin and epithelia, and strongly activates myeloid DCs. The TSLP-activated DCs secrete the inflammatory chemokines CCL17 and CCL22, prime an inflammatory Th2 response, and have been involved in the pathogenesis of allergic inflammation. By systematically comparing the response of human blood BDCA-1+ and BDCA-3+ DCs to TSLP stimulation we found that both of these DC subsets get activated by TSLP. However TSLP synergizes with TGF-β to induce the differentiation of blood BDCA-1+ and not BDCA-3+ DCs into Langerhans Cells. Moreover, TSLP induces cell migration and chemokine secretion only on the blood BDCA-1+ subset. Further analysis of the mechanisms implicated in TSLP-induced DC migration revealed that TSLP is required to induce DC migration, but this effect is dependent on the expression of a PTX-sensitive chemokine receptor. Overall our results reveal new precursor capacities of blood DC subsets, different functional properties of blood DC subsets stimulated by TSLP and highlight intricate mechanisms underlying TSLP-induced DC migration
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Galyas, Éva. "Concentrations of lead, copper and zinc in forest soils near industrial areas." Thesis, Högskolan i Halmstad, Akademin för ekonomi, teknik och naturvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-40363.
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Environmental contamination with heavy metals, especially of soils, has been a continuousproblem worldwide since the beginning of the industrial revolution. Heavy metal emissionshave increased continuously since 1900 and the metals accumulate in the environment. Pulpand paper mill factories, and factories which produce sulphuric acid emit heavy metals,among others lead (Pb), copper (Cu) and zinc (Zn). Results from previous studies showedthat the soils near factories had higher concentrations of these pollutants than the controlplace. In this study I want to determine the effects of industrial heavy metal emissions of onehistoric and one present industry on nearby soil heavy metal concentrations.Samples were taken near one historically heavily contaminated site, the old sulphite factoryin Rydöbruk (1897-1944) and near the present Stora Enso paper mill in Hyltebruk. As acontrol site, I compared these with Rocknen nature reserve area.At each site I took 6 soil samples, representing the top 15-20 cm of soil and organic material.Samples were analysed with an Atomic Absorption Spectrometer and the concentrations oflead, copper and zinc were determined per ashed dry material.I analyzed the samples at the laboratory using the guideline from the Swedish StandardInstitute for water analysis.The concentrations of the soil samples showed no significant difference between the naturereserve area and the industrial sites (One-way ANOVA). This was due to very variableorganic content within and between the sites.Organic content of the samples has a significantly effect on the metal concentrations for Pband Cu (Linear Regression test). In conclusion, metals can accumulate in the vegetation, andin case of Pb and Cu there is a correlation between their concentration and the amount oforganic matter. Therefore in future studies it is best if soil with very high organic content orvegetation is used to determine if forest soil near industries are affected by past or presentindustrial emissions of heavy metals.
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Juan, Cécile. "Compléxité de l'intégration multisensorielle chez le primate humain et non-humain : du comportement à l'électrophysiologie corticale et sous-corticale." Thesis, Toulouse 3, 2017. http://www.theses.fr/2017TOU30186/document.
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Dans notre environnement, nous sommes constamment exposés à de multiples stimuli sensoriels que notre cerveau doit analyser. Afin d'interagir avec le monde qui nous entoure, nous devons intégrer ces différentes sources d'informations sensorielles. L'étude des processus d'intégration multisensorielle est essentielle pour comprendre comment le cerveau intègre les éléments séparés d'un objet défini par plusieurs composantes sensorielles pour former un percept unifié. Il est maintenant couramment admis que la présentation conjointe de plusieurs informations sensorielles de modalités différentes d'un même stimulus peut faciliter la perception. Cette facilitation multisensorielle semble être soumise à des règles particulières puisque certains facteurs l'influencent. Parmi eux, nous avons étudié, dans notre première étude, l'impact de trois facteurs que sont la saillance, la congruence sémantique et le changement de modalité sur les performances de détection de stimuli naturels chez l'homme et le singe. L'utilisation de stimuli naturels nous a permis de mettre en lumière l'influence des paramètres physiques des stimuli sur l'intégration multisensorielle. De plus, nous avons montré que les effets de ces facteurs sur des stimuli naturels diffèrent de ceux retrouvés avec des stimuli simples. Ces résultats convergent vers des effets multifactoriels sur la facilitation multisensorielle dont la force, les interdépendances et l'ordre varieraient en fonction de la tâche comportementale et de ce fait, de la charge cognitive. D'un point de vue anatomique et plus précisément au niveau cortical, les processus d'intégration multisensorielle paraissaient être jusqu'à récemment une caractéristique que seules possédaient les aires associatives situées au sommet de la hiérarchie du traitement de l'information. On sait maintenant que des aires corticales de bas niveau, pensées jusque-là comme étant unisensorielles, sont impliquées dans les processus multisensoriels, soulevant ainsi la question des aires sous-corticales. Des études anatomiques ont mis en évidence l'existence de noyaux thalamiques qui, par leurs connexions, pourraient permettre un transfert rapide et même une intégration des informations sensorielles. Cette nouvelle littérature témoigne de la grande complexité des réseaux cérébraux de la multisensorialité. Dans deux études électrophysiologiques chez le singe, nous avons examiné les propriétés multisensorielles de deux structures, le gyrus cingulaire postérieur et le pulvinar médian, qui n'avaient jamais été explorées auparavant dans un contexte multisensoriel. Nous avons montré que ces structures sont non seulement multisensorielles mais également intégratives et qu'elles pourraient appartenir à un même système fonctionnel. Ces travaux de thèse ont apporté des éléments supplémentaires quant à notre compréhension des processus d'intégration multisensorielle au niveau comportemental et des réseaux cérébraux sous-jacents et particulièrement ceux liés à l'intégration de stimuli naturelsIn our environment, we are constantly exposed to multiple sensory stimuli that our brain has to analyze. To interact with the surrounding world, we have to integrate these different sources of sensory information. The study of the processes of multisensory integration are essential in understanding how our brain integrates the individual parts of an object defined by several sensory components to arrive at a unified percept. It is now widely accepted that the concurrent presentation of several sensory information about the same stimulus in different modalities can facilitate its perception. This multisensory facilitation seems to be subjected to specific rules since some factors influence it. Amongst them, we have studied, in our first experiment, the impact of three factors, namely saliency, semantic congruency and modality switch, on the detection of natural stimuli in humans and monkeys. Using natural stimuli enabled us to highlight the influence of the physical parameters of stimuli on multisensory integration. Moreover, we showed that the effect of these factors on natural stimuli are different from those found with simple stimuli. These results point toward multifactorial effects on multisensory facilitation, of which the force, the interdependency and the order would vary as a function of the behavioral task, and, thus as a function of the cognitive load. From an anatomical point of view and more specifically at the cortical level, the integration mechanism appeared to be, until recently, a characteristic possessed only by associative areas at the top of the hierarchy of information processing. We now know that low level cortical areas, thought up to then to be only unisensory, are implicated in multisensory processes, thus raising the question about subcortical areas. Anatomical studies have shown the existence of thalamic nuclei which, through their connectivity, could allow for a rapid transfer and even an integration of sensory information. This new literature demonstrates the high complexity of the multisensory cerebral networks. In two electrophysiological studies in the monkey, we examined the multisensory properties of two structures, the posterior cingulate gyrus and the median pulvinar, which had never been explored before in a multisensory context. We not only showed that these structures are multisensory, but also integrative and that they could be part of the same functional network. This thesis has brought additional elements towards a better understanding of multisensory integration processes at the behavioral level and about the underlying brain networks, in particular those linked with the integration of natural stimuli
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Harb, Shaban Ramadan Mohamed. "On the human radiation exposure as derived from the analysis of natural and man-made radionuclides in soils." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971237573.
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Robson, Thomas. "Weathering of sulfide ores in model soils, potentially toxic element release and bioavailability." Thesis, University of Plymouth, 2013. http://hdl.handle.net/10026.1/2859.
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The exploitation of metallic sulfide ores produces vast quantities of fine-grained wastes hosting potentially toxic elements (PTEs). There are concerns that, if improperly disposed of and managed, waste mineral particles can behave as vectors that disperse PTEs via aeolian and fluvial transport, subsequently contaminating soils and crops used to support human populations. The importance of these particles, as sources and influencers of PTE biogeochemistry in productive soils, has received limited research. Long-term (365 d) batch incubation experiments, field weathering experiments and phytoavailability trials, were performed to establish the rate, patterns and factors limiting PTE (Cd, As, Hg) release from grains of sphalerite (Zn(Fe,Cd)S), arsenopyrite (FeAsS) and cinnabar (HgS) into soil matrices (0.1 % mineral:soil m/m), and the bioavailability of the liberated PTEs to important food crops (Tricitum aestivum, wheat and Oryza sativa, rice). All three of the ores underwent chemical weathering in oxic agricultural soils of both temperate and sub-tropical provenance, during which nonessential PTEs (cadmium, mercury, arsenic) were released in bioavailable forms, at rates relevant to agricultural production. Sphalerite weathered at a rate of 0.6 to 1.2 % a-1 (Cd basis) in the experimental soils, releasing 0.5 to 1 μmol Cd g-1 ZnS a-1 into the soil matrix. Cinnabar weathering reached a maximum of 12.0 – 13.5 % (Hg basis) after 90 days exposure in oxic soils, whereas arsenopyrite weathering was rapid and extensive, reaching 56 to 66 % (S basis) after 180 days. The PTE concentrations accumulated in edible grains of wheat and rice grown in the sulfide-contaminated soils were higher than international food safety limits by factors of 8 (Cd in rice), 10 – 30 (Hg in wheat and rice) and 8 – 12 (As in wheat and rice). The primary geochemical factors controlling PTE release and bioavailability were solid-phase associations (i.e. PTEs complexed by clays, metal oxyhydroxides and organic matter) and the precipitation of secondary mineral phases. Weathering arsenopyrite grains were passivated from further oxidation by secondary iron-arsenate phases, which also co-precipitated arsenic liberated from the ore. Secondary phase formation was identified as the cause of decreasing extractable Hg (liberated from cinnabar) after mercury release from cinnabar peaked (≤ 90 days exposure). For sphalerite, the evidence indicates that secondary sulfide phases formed under flooded (sulfate-reducing) soil conditions (paddy rice), limited the bioavailability of cadmium previously liberated under oxic conditions. These key findings demonstrate a potential human health hazard relating to the dispersal of PTE-hosting sulfide ore particles produced by mining activities into soils supporting human populations via crop contamination. This work also highlights differences in ore geochemistry, showing the need for additional research on different ore minerals and their alteration products.
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Vinet, Jonathan. "Neurogénèse post-natale, étude de la zone sous-ventriculaire dans le cerveau humain adulte." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0018/MQ49056.pdf.
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Marguerie, Dominique. "Evolution de la végétation sous l'impact humain en Armorique du Néolithique aux périodes historiques /." Rennes : Université de Rennes 1, 1992. http://catalogue.bnf.fr/ark:/12148/cb355716755.
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Ancelin, Magali. "Etude du facteur VEGF 189 produit dans l'endomètre humain sous l'influence de la progestérone." Paris 6, 2002. http://www.theses.fr/2002PA066011.
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Jacq, Xavier. "Clonage et caracterisation de htaf#i#i30, une sous-unite du complexe tfiid humain." Université Louis Pasteur (Strasbourg) (1971-2008), 1997. http://www.theses.fr/1997STR13146.
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La regulation de l'expression des genes de classe ii (i. E. Les genes transcrits en arn messagers) est assuree chez les eucaryotes superieurs par trois familles de facteurs de transcription. La premiere est constituee des facteurs de transcription dits generaux qui, associes a l'arn pol ii constituent la machinerie transcriptionnelle de base. La seconde categorie comprend les facteurs regulateurs specifiques de tissus ou de cellules qui permettent une regulation fine et precise de l'expression spatio-temporelle des genes : ce sont les activateurs/represseurs transcriptionnels. Le troisieme groupee comprend les coactivateurs : ces facteurs permettent de faire le lien entre les modulateurs et la machinerie transcriptionnelle de base. Le facteur general de transcription tfiid, implique dans la transcription des genes par l'arn pol ii, est compose de la proteine de liaison a la boite tata (tbp) et de facteurs associes (facteurs associes a tbp ou taf#i#is). La proteine tbp lie la sequence tata et initie la formation du complexe de preinitiation. Les taf#i#is ont etes initialement caracterises comme des coactivateurs essentiels a l'activation de la transcription in vitro car la proteine tbp seule est incapable de permettre l'activation de la transcription dans un systeme in vitro. Les taf#i#is ne jouent pas uniquement un role dans l'activation de la transcription mais possedent aussi certaines fonctions de facteurs generaux comme la reconnaissance du promoteur minimal. La presente etude concerne la caracterisation de l'heterogeneite des complexes tfiid. Ce projet a aboutit au clonage de l'adnc et du gene codant pour un facteur humain associe a tbp dans le complexe tfiid, htaf#i#i30, qui n'est present que dans certaines sous-populations de complexes tfiid. La caracterisation de htaf#i#i30 a permis la separation physique et fonctionnelle de differents complexes tfiid. Dans un systeme de transcription in vitro, l'activation de la transcription par le recepteur des strogenes est dependante de la presence des complexes tfiid qui contiennent htaf#i#i30. Les complexes tfiid qui ne contiennent pas htaf#i#i30 permettent toujours l'activation de la transcription par le domaine d'activation de la transcription de la proteine vp16 du virus herpes simplex. Des etudes d'interactions in vitro ont montre que htaf#i#i30 interagit avec le domaine de liaison de l'hormone du recepteur des strogenes.